Methods for predicting drug responsiveness

ABSTRACT

The present invention provides drug response predictors and biomarkers useful for assessing the responsiveness of a subject to treatment with one or more target drugs of interest, such as 5-fluorouracil (5-FU), irinotecan, and/or oxaliplatin. In particular, the invention provides methods useful in determining whether a subject is sensitive or resistant to a target drug by, e.g., measuring the expression level of one or more biomarkers of sensitivity and/or resistance to the drug in a biological sample obtained from the subject. The invention further features devices and kits for assessing target drug responsiveness in a subject, for example, by determining the expression level of such biomarkers.

FIELD OF THE INVENTION

The invention features methods, devices, and kits for assessing cancer patient responsiveness to chemotherapy drugs.

BACKGROUND

Gene expression analysis can reveal the presence of a disease, such as cancer, in a patient, its type, stage, and origin, and whether genetic mutations are involved. Gene expression analysis can also be used to predict the efficacy of a therapy. For example, the National Cancer Institute (NCI) has tested compounds, including chemotherapy agents, for their effect in limiting the growth of 60 human cancer cell lines. NCI has also measured gene expression in those 60 cancer cell lines using DNA microarrays. Various studies have explored the relationship between gene expression and compound effect using the NCI datasets.

The antimetabolite 5-flourouracil (5-FU) is the standard of care in systemic treatment of primary and metastatic colorectal cancer, with further activity in a wide range of solid tumors, including other gastrointestinal malignancies, breast cancer, head and neck cancers, and ovarian carcinomas. It is manufactured not only as 5-FU, but also as an oral agent, capecitabine, and as a prodrug, tegafur (DeVita et al., DeVita, Hellmann, and Rosenberg's Cancer: Principles and Practice of Oncology, 8^(th) ed., Philadelphia, Lippincott Williams and Wilkins, 2005). 5-FU treatment results in a survival benefit in the adjuvant setting of colorectal cancer (Rougier et al., Ann Oncol. 1993;4 Suppl 2:21-8). Response rates for 5-FU monotherapy in metastatic colorectal cancer are low (10-15%) (Longley et al., Nat. Rev. Cancer 3: 330-338, 2003), therefore it is currently combined with either topoisomerase-1 inhibitor irinotecan as FOLFIRI regimen or platinum-based oxaliplatin as a FOLFOX regimen and targeted EGFR-inhibitor cetuximab according to KRAS-status. Many rivaling factors at the level of both tumor cell characteristics and patient variability may impact the efficacy of 5-FU (Longley et al., supra). After three decades of examining potential predictive biomarkers, the results are mostly far from any clinical realization.

Adjuvant treatment of stage II to III colorectal cancer patients has stagnated, even with many attempts at introducing new drugs in the past decade (Venook et al., Am. Soc. Clin. Oncol. 83-89, 2014). Biomarkers to assist physicians with respect to prognosis, prediction of treatment efficacy, and expected severe toxicities to antineoplastic treatment of colon cancer are and have long been eagerly awaited. Although research on prognostic biomarkers in colon cancer began as early as 1981, few prognostic biomarkers have been implemented clinically except for carcinoembryonic antigen (CEA) (Ichiki et al., Oncology 38: 27-30, 1981) and microsatellite instability (MSI) (Reimers et al., supra), even though many have been examined (Roth et al., Natl. Cancer Inst. 104: 1635-1646, 2012; Bezulier et al., J. Clin. Pharm. Ther. 28: 403-408, 2003; Watanabe et al., N. Engl. J. Med. 344: 1196-1206, 2001; Allegra et al., J. Clin. Oncol. 20: 1735-1743, 2002).

Furthermore, during chemotherapy for cancers, critical time is often lost due to a trial and error approach to finding an effective therapy. In addition, cancer cells often develop resistance to a previously effective therapy. In such situations, patient outcome would be greatly improved by early detection of such resistance. Thus, there is a need in the art for proven methods, kits, and devices that can be used to predict the sensitivity or resistance of cancer patients to treatment with chemotherapeutic drugs.

SUMMARY OF THE INVENTION

The invention enables the assessment of responsiveness of a subject to treatment with a target drug of interest, e.g., by determining the expression level of one or more biomarkers of sensitivity or resistance to the drug, such as the biomarkers disclosed herein. Exemplary target drugs for which a subject's responsiveness can be assessed by the methods of the present invention include 5-fluorouracil (5-FU), capecitabine, tegafur, irinotecan, oxaliplatin, and derivatives, analogs, and prodrugs thereof.

In a first aspect, the invention features a method of assessing the responsiveness of a subject to treatment with 5-fluorouracil (5-FU) by:

(a) determining a level of expression of one or more biomarkers of resistance selected from, e.g., the biomarkers of Table 2 in one or more biological samples obtained from the subject; or

(b) determining a level of expression of one or more biomarkers of sensitivity selected from, e.g., the biomarkers of Table 1 in one or more biological samples obtained from the subject;

in which the levels of expression of the biomarker of resistance or the biomarker of sensitivity indicates whether the subject is responsive to the treatment.

In some embodiments, the method further includes, prior to the determining of (a) or (b), providing the one or more biological samples obtained from the subject.

In certain embodiments, the method includes:

(a) determining a level of expression of one or more biomarkers of sensitivity selected from, e.g., the biomarkers of Table 1 in one or more biological samples obtained from the subject; and

(b) determining a level of expression of one or more biomarkers of resistance selected from, e.g., the biomarkers of Table 2 in one or more biological samples obtained from the subject.

In particular embodiments, the difference between the levels of expression of the one or more biomarkers of sensitivity and the one or more biomarkers of resistance indicates whether the subject is responsive to the treatment.

In some embodiments, the method further includes: (c) if the levels of expression of the one or more biomarkers of sensitivity or the one or more biomarkers of resistance indicate that the subject is responsive to 5-FU, administering an effective amount of the 5-FU to the subject.

In a second aspect, the invention features a method of treating a subject by:

(a) determining a level of expression of one or more biomarkers of resistance selected from, e.g., the biomarkers of Table 2 in one or more biological samples obtained from the subject; or

(b) determining a level of expression of one or more biomarkers of sensitivity selected from, e.g., the biomarkers of Table 1 in one or more biological samples obtained from the subject; and

(c) if the levels of expression of the one or more biomarkers of sensitivity or the one or more biomarkers of resistance indicate that the subject is responsive to 5-FU (e.g., according to the methods of the invention), administering an effective amount of 5-FU to the subject.

In some embodiments, the method includes:

(a) determining a level of expression of one or more biomarkers of sensitivity selected from, e.g., the biomarkers of Table 1 in one or more biological samples obtained from the subject; and

(b) determining a level of expression of one or more biomarkers of resistance selected from, e.g., the biomarkers of Table 2 in one or more biological samples obtained from the subject.

In a third aspect, the invention features a method of treating a subject, the subject having previously been determined to be responsive to treatment with 5-FU by:

(a) determining a level of expression of one or more biomarkers of sensitivity selected from, e.g., the biomarkers of Table 1 in one or more biological samples obtained from the subject; or

(b) determining a level of expression of one or more biomarkers of resistance selected from, e.g., the biomarkers of Table 2 in one or more biological samples obtained from the subject;

in which the levels of expression of the biomarker of sensitivity or the biomarker of resistance indicates whether the subject is responsive to the treatment;

the method including administering an effective amount of 5-FU to the subject.

In some embodiments of any of the above aspects, the method further includes administering one or more additional therapies to the subject.

In some embodiments, the one or more additional therapies is administered concurrently with the administration of 5-FU. In other embodiments, the one or more additional therapies is administered separately from the administration of 5-FU. In certain embodiments, the one or more additional therapies is administered prior to the administration of 5-FU. In alternate embodiments, the one or more additional therapies is administered after the administration of 5-FU. In particular embodiments, the one or more additional therapies is administered within 1 week of the administration of 5-FU (e.g., within about 15 minutes, 30 minutes, 1 hour, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours, 8 hours, 10 hours, 12 hours, 24 hours, 36 hours, 2 days, 3 days, 4 days, 5 days, 6 days, or 1 week of the administration of 5-FU).

In some embodiments, the one or more additional therapies includes one or more additional therapeutic agents, surgery, or radiation therapy. In certain embodiments, the one or more additional therapies includes one or more additional therapeutic agents. In particular embodiments, the 5-FU is administered alone or in admixture with the one or more additional therapeutic agents.

In some embodiments, the one or more additional therapeutic agents is selected from the group consisting of: irinotecan, oxaliplatin, cetuximab, leucovorin, SN-38, everolimus, temsirolimus, bleomycin, lomustine, depsipeptide, carboplatin, bortezomib, erlotinib, gemcitabine, mitoxantrone, cisplatin, busulfan, epirubicin, arsenic trioxide, bendamustine, vincristine, fulvestrant, teniposide, adriamycin, decitabine, estramustine, other chemotherapeutic agents known in the art, and combinations thereof. In certain embodiments, the one or more additional therapeutic agents includes everolimus, temsirolimus, bleomycin, or lomustine. In particular embodiments, the one or more therapeutic agents includes leucovorin and at least one of irinotecan or oxaliplatin.

In some embodiments, the one or more additional therapeutic agents is administered to the subject intravenously, orally, intraperitoneally, intramuscularly, topically, rectally, cutaneously, subcutaneously, nasally, intracerebroventricularly, intraparenchymally, intrathecally, intracranially, ocularly, via inhalation, or through the skin. In various embodiments, the one or more additional therapeutic agents is administered in dosage form.

In some embodiments, the 5-FU is administered to the subject intravenously, orally, intraperitoneally, intramuscularly, topically, rectally, cutaneously, subcutaneously, nasally, intracerebroventricularly, intraparenchymally, intrathecally, intracranially, ocularly, via inhalation, or through the skin. In certain embodiments, the 5-FU is administered to the subject intravenously.

In some embodiments, the method further includes one or more additional administrations of an effective amount of 5-FU to the subject. In certain embodiments, the 5-FU is administered to the subject once daily. In particular embodiments, the 5-FU is administered to the subject once daily for up to four days. In specific embodiments, the administration of 5-FU is repeated 30 days after the completion of the previous administration. In certain embodiments, the administration of 5-FU is repeated for at least 12 to 60 months (e.g., at least 12 months, 13 months, 14 months, 15 months, 16 months, 17 months, 18 months, 19 months, 20 months, 24 months, 25 months, 30 months, 36 months, 40 months, 48 months, 50 months, or 60 months).

In various embodiments, the 5-FU is administered in dosage form. In certain embodiments, the 5-FU is administered in daily doses of up to 800 mg (e.g., about 50 mg, 100 mg, 150 mg, 200 mg, 250 mg, 300 mg, 400 mg, 500 mg, 600 mg, 700 mg, or 800 mg).

In some embodiments, the determining step (a) or (b) occurs prior to the administration. In alternate embodiments, the determining step (a) or (b) occurs concurrent with the administration. In certain embodiments, the determining step (a) or (b) occurs after the administration. In various embodiments, the determining step (a) or (b) occurs multiple times.

In some embodiments, the administration occurs multiple times. In certain embodiments, each of the determining step (a) or (b) occurs prior to each of the administrations. In other embodiments, each of the determining step (a) or (b) occurs concurrent with each of the administrations. In specific embodiments, each of the determining step (a) or (b) occurs after each of the administrations.

In some embodiments of any of the above aspects, the biomarker of resistance is NT5E. In certain embodiments, the expression level of the NT5E indicates the resistance of the subject to the treatment.

In some embodiments of any of the above aspects, one or more of the biomarkers of resistance is selected from the group consisting of: NT5E, CNN3, ACTN1, FLNA, ATP2B4, CYR61, LGALS1, RHOC, RAB32, and TMEM158; and/or one or more of the biomarkers of sensitivity is selected from the group consisting of: APRT, GSR, TUFM, MRPS2, MTHFD2, WDR59, ANP32B, PMM2, STOML2, and NDUFAB1.

In some embodiments of any of the above aspects, one or more of the biomarkers of resistance is selected from the group consisting of: NT5E, CNN3, ACTN1, FLNA, and ATP2B4; and/or one or more of the biomarkers of sensitivity is selected from the group consisting of: APRT, GSR, TUFM, MRPS2, and MTHFD2.

In certain embodiments, the difference between the expression levels of the one or more biomarkers of sensitivity and the one or more biomarkers of resistance indicates the sensitivity of the subject to the treatment. In various embodiments, the expression levels of the one or more biomarkers of sensitivity in the subject having a statistically significant difference from the expression levels of the one or more biomarkers of sensitivity in a control indicates the sensitivity of the subject to the treatment. In particular embodiments, the expression levels of the one or more biomarkers of resistance in the subject having a statistically significant difference from the expression levels of the one or more biomarkers of resistance in a control indicates the resistance of the subject to the treatment. In specific embodiments, the expression level in the subject is significantly higher than in the control. In alternate embodiments, the expression level in the subject is significantly lower than in the control.

In a fourth aspect, the invention features a method of assessing the responsiveness of a subject to treatment with irinotecan by:

(a) determining a level of expression of one or more biomarkers of sensitivity selected from, e.g., the biomarkers of Table 3 in one or more biological samples obtained from the subject; or

(b) determining a level of expression of one or more biomarkers of resistance selected from, e.g., the biomarkers of Table 4 in one or more biological samples obtained from the subject;

in which the levels of expression of the biomarker of sensitivity or the biomarker of resistance indicates whether the subject is responsive to the treatment.

In some embodiments, the method includes, prior to the determining step (a) or (b), providing the one or more biological samples obtained from the subject.

In certain embodiments, the method includes:

(a) determining a level of expression of one or more biomarkers of sensitivity selected from, e.g., the biomarkers of Table 3 in one or more biological samples obtained from the subject; and

(b) determining a level of expression of one or more biomarkers of resistance selected from, e.g., the biomarkers of Table 4 in one or more biological samples obtained from the subject.

In particular embodiments, the difference between the levels of expression of the one or more biomarkers of sensitivity and the one or more biomarkers of resistance indicates whether the subject is responsive to the treatment.

In specific embodiments, the method further includes: (c) if the levels of expression of the one or more biomarkers of sensitivity or the one or more biomarkers of resistance indicate that the subject is responsive to irinotecan, administering an effective amount of the irinotecan to the subject.

In a fifth aspect, the invention features a method of treating a subject by:

(a) determining a level of expression of one or more biomarkers of sensitivity selected from, e.g., the biomarkers of Table 3 in one or more biological samples obtained from the subject; or

(b) determining a level of expression of one or more biomarkers of resistance selected from, e.g., the biomarkers of Table 4 in one or more biological samples obtained from the subject; and

(c) if the levels of expression of the one or more biomarkers of sensitivity or the one or more biomarkers of resistance indicate that the subject is responsive to irinotecan, administering an effective amount of irinotecan to the subject.

In some embodiments, the method includes:

(a) determining a level of expression of one or more biomarkers of sensitivity selected from, e.g., the biomarkers of Table 3 in one or more biological samples obtained from the subject; and

(b) determining a level of expression of one or more biomarkers of resistance selected from, e.g., the biomarkers of Table 4 in one or more biological samples obtained from the subject.

In a sixth aspect, the invention features a method of treating a subject, the subject having previously been determined to be responsive to treatment with irinotecan by:

(a) determining a level of expression of one or more biomarkers of sensitivity selected from, e.g., the biomarkers of Table 3 in one or more biological samples obtained from the subject; or

(b) determining a level of expression of one or more biomarkers of resistance selected from, e.g., the biomarkers of Table 4 in one or more biological samples obtained from the subject;

in which the levels of expression of the biomarker of sensitivity or the biomarker of resistance indicates whether the subject is responsive to the treatment;

the method including administering an effective amount of irinotecan to the subject.

In some embodiments of any of the above aspects, the method further includes administering one or more additional therapies to the subject.

In some embodiments, the one or more additional therapies is administered concurrently with the administration of irinotecan. In other embodiments, the one or more additional therapies is administered separately from the administration of irinotecan. In certain embodiments, the one or more additional therapies is administered prior to the administration of irinotecan. In alternate embodiments, the one or more additional therapies is administered after the administration of irinotecan. In particular embodiments, the one or more additional therapies is administered within 1 week of the administration of irinotecan (e.g., within about 15 minutes, 30 minutes, 1 hour, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours, 8 hours, 10 hours, 12 hours, 24 hours, 36 hours, 2 days, 3 days, 4 days, 5 days, 6 days, or 1 week of the administration of irinotecan).

In some embodiments, the one or more additional therapies includes one or more additional therapeutic agents, surgery, or radiation therapy. In certain embodiments, the one or more additional therapies includes one or more additional therapeutic agents. In particular embodiments, the irinotecan is administered alone or in admixture with the one or more additional therapeutic agents.

In some embodiments, the one or more additional therapeutic agents is selected from the group consisting of: 5-FU, oxaliplatin, cetuximab, leucovorin, SN-38, everolimus, temsirolimus, bleomycin, lomustine, depsipeptide, carboplatin, bortezomib, erlotinib, gemcitabine, mitoxantrone, cisplatin, busulfan, epirubicin, arsenic trioxide, bendamustine, vincristine, fulvestrant, teniposide, adriamycin, decitabine, estramustine, other chemotherapeutic agents known in the art, and combinations thereof. In certain embodiments, the one or more additional therapeutic agents includes everolimus, temsirolimus, bleomycin, or lomustine. In particular embodiments, the one or more therapeutic agents includes 5-FU and leucovorin.

In some embodiments, the one or more additional therapeutic agents is administered to the subject intravenously, orally, intraperitoneally, intramuscularly, topically, rectally, cutaneously, subcutaneously, nasally, intracerebroventricularly, intraparenchymally, intrathecally, intracranially, ocularly, via inhalation, or through the skin. In various embodiments, the one or more additional therapeutic agents is administered in dosage form.

In some embodiments, the irinotecan is administered to the subject intravenously, orally, intraperitoneally, intramuscularly, topically, rectally, cutaneously, subcutaneously, nasally, intracerebroventricularly, intraparenchymally, intrathecally, intracranially, ocularly, via inhalation, or through the skin. In certain embodiments, the irinotecan is administered to the subject intravenously.

In some embodiments, the method further includes one or more additional administrations of an effective amount of irinotecan to the subject. In certain embodiments, the irinotecan is administered to the subject once weekly, once every other week, or once every three weeks. In particular embodiments, the irinotecan is administered to the subject in six week cycles (e.g., every six weeks). In various embodiments, the administration of irinotecan is repeated for at least 12 to 60 months (e.g., at least 12 months, 13 months, 14 months, 15 months, 16 months, 17 months, 18 months, 19 months, 20 months, 24 months, 25 months, 30 months, 36 months, 40 months, 48 months, 50 months, or 60 months).

In some embodiments, the irinotecan is administered in dosage form. In certain embodiments, the irinotecan is administered in doses of up to 125 mg/m², 180 mg/m², or 350 mg/m². (e.g., about 10 mg/m², 20 mg/m², 30 mg/m², 40 mg/m², 50 mg/m², 100 mg/m², 125 mg/m², 150 mg/m², 175 mg/m², 180 mg/m², 200 mg/m², 250 mg/m², 300 mg/m², or 350 mg/m²).

In some embodiments, the determining step (a) or the determining step (b) occurs prior to the administration. In other embodiments, the determining step (a) or the determining step (b) occurs concurrent with the administration. In various embodiments, the determining step (a) or the determining step (b) occurs after the administration. In certain embodiments, the determining step (a) or the determining step (b) occurs multiple times.

In some embodiments, the administration occurs multiple times. In certain embodiments, each of the determining step (a) or the determining step (b) occurs prior to each of the administrations. In alternate embodiments, each of the determining step (a) or the determining step (b) occurs concurrent with each of the administrations. In further embodiments, each of the determining step (a) or the determining step (b) occurs after each of the administrations.

In some embodiments, the biomarker of sensitivity is PRF1. In certain embodiments, the expression level of the PRF1 indicates the sensitivity of the subject to the treatment.

In some embodiments, one or more of the biomarkers of sensitivity is selected from the group consisting of: PRF1, GZMB, PTPRC, PTPRC, PTPRCAP, PDE4DIP, ACAP1, PTPRC, S1PR1, and DOCK2; and/or one or more of the biomarkers of resistance is selected from the group consisting of: CCND1, LGALS3, INPP4B, TMEM97, TCF7L2, SFN, LAPTM4B, LSR, SFN, and TMEM97.

In some embodiments, one or more of the biomarkers of sensitivity is selected from the group consisting of: PRF1, GZMB, PTPRC, PTPRC, and PTPRCAP; and/or one or more of the biomarkers of resistance is selected from the group consisting of: CCND1, LGALS3, INPP4B, TMEM97, and TCF7L2.

In various embodiments, the difference between the expression levels of the one or more biomarkers of sensitivity and the one or more biomarkers of resistance indicates the sensitivity of the subject to the treatment. In certain embodiments, the expression levels of the one or more biomarkers of sensitivity in the subject having a statistically significant difference from the expression levels of the one or more biomarkers of sensitivity in a control indicates the sensitivity of the subject to the treatment. In particular embodiments, the expression levels of the one or more biomarkers of resistance in the subject having a statistically significant difference from the expression levels of the one or more biomarkers of resistance in a control indicates the resistance of the subject to the treatment. In specific embodiments, the expression level in the subject is significantly higher than in the control. In alternate embodiments, the expression level in the subject is significantly lower than in the control.

In a seventh aspect, the invention features a method of assessing the responsiveness of a subject to treatment with oxaliplatin by:

(a) determining a level of expression of one or more biomarkers of sensitivity selected from, e.g., the biomarkers of Table 5 in one or more biological samples obtained from the subject; or

(b) determining a level of expression of one or more biomarkers of resistance selected from, e.g., the biomarkers of Table 6 in one or more biological samples obtained from the subject;

in which the levels of expression of the biomarker of sensitivity or the biomarker of resistance indicates whether the subject is responsive to the treatment.

In some embodiments, the method includes, prior to the determining of (a) or (b), providing the one or more biological samples obtained from the subject.

In some embodiments, the method includes:

(a) determining a level of expression of one or more biomarkers of sensitivity selected from, e.g., the biomarkers of Table 5 in one or more biological samples obtained from the subject; and

(b) determining a level of expression of one or more biomarkers of resistance selected from, e.g., the biomarkers of Table 6 in one or more biological samples obtained from the subject.

In certain embodiments, the difference between the levels of expression of the one or more biomarkers of sensitivity and the one or more biomarkers of resistance indicates whether the subject is responsive to the treatment.

In some embodiments, the method further includes: (c) if the levels of expression of the one or more biomarkers of sensitivity or the one or more biomarkers of resistance indicate that the subject is responsive to oxaliplatin, administering an effective amount of the oxaliplatin to the subject.

In an eighth aspect, the invention features a method of treating a subject by:

(a) determining a level of expression of one or more biomarkers of sensitivity selected from, e.g., the biomarkers of Table 5 in one or more biological samples obtained from the subject; or

(b) determining a level of expression of one or more biomarkers of resistance selected from, e.g., the biomarkers of Table 6 in one or more biological samples obtained from the subject;

(c) if the levels of expression of the one or more biomarkers of sensitivity or the one or more biomarkers of resistance indicate that the subject is responsive to oxaliplatin, administering an effective amount of oxaliplatin to the subject.

In some embodiments, the method includes the determining of (a) and the determining of (b).

In a ninth aspect, the invention features a method of treating a subject, the subject having previously been determined to be responsive to treatment with oxaliplatin by:

(a) determining a level of expression of one or more biomarkers of sensitivity selected from, e.g., the biomarkers of Table 5 in one or more biological samples obtained from the subject; or

(b) determining a level of expression of one or more biomarkers of resistance selected from, e.g., the biomarkers of Table 6 in one or more biological samples obtained from the subject;

in which the levels of expression of the biomarker of sensitivity or the biomarker of resistance indicates whether the subject is responsive to the treatment;

the method including administering an effective amount of oxaliplatin to the subject.

In some embodiments, the method further includes administering one or more additional therapies to the subject. In certain embodiments, the one or more additional therapies is administered concurrently with the administration of oxaliplatin. In alternate embodiments, the one or more additional therapies is administered separately from the administration of oxaliplatin. In particular embodiments, the one or more additional therapies is administered prior to the administration of oxaliplatin. In other embodiments, the one or more additional therapies is administered after the administration of oxaliplatin. In certain embodiments, the one or more additional therapies is administered within 1 week of the administration of oxaliplatin.

In some embodiments, the one or more additional therapies includes one or more additional therapeutic agents, surgery, or radiation therapy. In certain embodiments, the one or more additional therapies includes one or more additional therapeutic agents. In particular embodiments, the oxaliplatin is administered alone or in admixture with the one or more additional therapeutic agents. In various embodiments, the one or more additional therapeutic agents is selected from the group consisting of: 5-FU, irinotecan, capecitabine, tegafur, cetuximab, leucovorin, SN-38, everolimus, temsirolimus, bleomycin, lomustine, depsipeptide, carboplatin, bortezomib, erlotinib, gemcitabine, mitoxantrone, cisplatin, busulfan, epirubicin, arsenic trioxide, bendamustine, vincristine, fulvestrant, teniposide, adriamycin, decitabine, and estramustine. In certain embodiments, the one or more additional therapeutic agents includes everolimus, temsirolimus, bleomycin, or lomustine. In particular embodiments, the one or more additional therapeutic agents includes 5-FU and leucovorin.

In some embodiments, the one or more additional therapeutic agents is administered to the subject intravenously, orally, intraperitoneally, intramuscularly, topically, rectally, cutaneously, subcutaneously, nasally, intracerebroventricularly, intraparenchymally, intrathecally, intracranially, ocularly, via inhalation, or through the skin. In some embodiments, the one or more additional therapeutic agents is administered in dosage form.

In various embodiments, the oxaliplatin is administered to the subject intravenously, orally, intraperitoneally, intramuscularly, topically, rectally, cutaneously, subcutaneously, nasally, intracerebroventricularly, intraparenchymally, intrathecally, intracranially, ocularly, via inhalation, or through the skin. In specific embodiments, the oxaliplatin is administered to the subject intravenously.

In some embodiments, the method further includes one or more additional administrations of an effective amount of oxaliplatin to the subject. In certain embodiments, the oxaliplatin is administered to the subject once every two weeks. In particular embodiments, the oxaliplatin is administered to the subject once every two weeks for up to six months. In various embodiments, the administration of oxaliplatin is repeated for at least 12 to 60 months (e.g., at least 12 months, 13 months, 14 months, 15 months, 16 months, 17 months, 18 months, 19 months, 20 months, 24 months, 25 months, 30 months, 36 months, 40 months, 48 months, 50 months, or 60 months).

In some embodiments, the oxaliplatin is administered in dosage form. In certain embodiments, the oxaliplatin is administered in doses of up to 85 mg/m². (e.g., about 10 mg/m², 20 mg/m², 30 mg/m², 40 mg/m², 50 mg/m², 60 mg/m², 70 mg/m², 80 mg/m², or 86 mg/m²).

In some embodiments, the determining of (a) or the determining of (b) occurs prior to the administration. In alternate embodiments, the determining step (a) or the determining step (b) occurs concurrent with the administration. In various embodiments, the determining step (a) or the determining step (b) occurs after the administration. In certain embodiments, the determining step (a) or the determining step (b) occurs multiple times.

In some embodiments, the administration occurs multiple times. In certain embodiments, each of the determining step (a) or the determining step (b) occurs prior to each of the administrations. In alternative embodiments, each of the determining step (a) or the determining step (b) occurs concurrent with each of the administrations. In various embodiments, each of the determining step (a) or the determining step (b) occurs after each of the administrations.

In some embodiments of any of the above aspects, the biomarker of sensitivity is selected from MRPL16 and at least a second biomarker of sensitivity selected from the biomarkers of Table 5. In certain embodiments, the second biomarker of sensitivity is selected from the group consisting of: ANP32A, SRSF2, PDSS1, PRIM1, HNRNPA1, NDUFAB1, GLTSCR2, RNPS1, and ICAM2. In particular embodiments, the second biomarker of sensitivity is selected from the group consisting of: ANP32A, SRSF2, PDSS1, and PRIM1. In specific embodiments, the second biomarkers of sensitivity is ANP32A.

In some embodiments, the biomarker of sensitivity is selected from MRPL16 and the biomarker of resistance is selected from one or more of the biomarkers of Table 6. In certain embodiments, the biomarker of resistance is selected from the group consisting of: LPP, RHOC, CAPN2, FLNA, WDR1, FLNA, ACTN1, CNN3, FLNA, and ACTN1. In particular embodiments, the biomarker of resistance is selected from the group consisting of: LPP, RHOC, CAPN2, FLNA, and WDR1. In specific embodiments, the biomarker of resistance is LPP.

In some embodiments, one or more of the biomarkers of sensitivity is selected from the group consisting of: MRPL16, ANP32A, SRSF2, PDSS1, PRIM1, HNRNPA1, NDUFAB1, GLTSCR2, RNPS1, and ICAM2; and/or one or more of the biomarkers of resistance is selected from the group consisting of: LPP, RHOC, CAPN2, FLNA, WDR1, FLNA, ACTN1, CNN3, FLNA, and ACTN1.

In some embodiments, one or more of the biomarkers of sensitivity is selected from the group consisting of: MRPL16, ANP32A, SRSF2, PDSS1, and PRIM1; and/or one or more of the biomarkers of resistance is selected from the group consisting of: LPP, RHOC, CAPN2, FLNA, and WDR1.

In some embodiments, the difference between the expression levels of the one or more biomarkers of sensitivity and the one or more biomarkers of resistance indicates the sensitivity of the subject to the treatment.

In some embodiments, the method further involves predicting sensitivity of the subject to combination treatment with oxaliplatin and 5-FU, and the method further includes: (c) determining a level of expression of one or more biomarkers of resistance to 5-FU selected from the biomarkers of Table 2 in one or more biological samples obtained from the subject; in which the biomarker of sensitivity is MRPL16. In certain embodiments, the one or more biomarkers of resistance to 5-FU is selected from the group consisting of: NT5E, CNN3, ACTN1, FLNA, ATP2B4, CYR61, LGALS1, RHOC, RAB32, and TMEM158. In particular embodiments, the one or more biomarkers of resistance to 5-FU is selected from the group consisting of: NT5E, CNN3, ACTN1, FLNA, and ATP2B4. In a specific embodiment, the biomarker of resistance to 5-FU is NT5E.

In particular embodiments, the expression level of NT5E is determined using a probe capable of detecting a nucleic acid having the sequence of, e.g., SEQ ID NO. 94, 1015, 1016, 1683, 2064, 2207, 2316, 2446, 2714, or 2778. In specific embodiments, the probe includes a sequence having at least 5 continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence complementary to, e.g., SEQ ID NO. 94, 1015, 1016, 1683, 2064, 2207, 2316, 2446, 2714, or 2778.

In certain embodiments, the difference between the expression levels of the MRPL16 and the one or more biomarkers of resistance to 5-FU indicate the sensitivity of the subject to the combination treatment with oxaliplatin and 5-FU.

In various embodiments, the expression levels of the one or more biomarkers of sensitivity in the subject having a statistically significant difference from the expression levels of the one or more biomarkers of sensitivity in a control indicates the sensitivity of the subject to the treatment. In some embodiments, the expression levels of the one or more biomarkers of resistance in the subject having a statistically significant difference from the expression levels of the one or more biomarkers of resistance in a control indicates the resistance of the subject to the treatment. In certain embodiments, the expression level in the subject is significantly higher than in the control. In alternate embodiments, the expression level in the subject is significantly lower than in the control.

In some embodiments of any of the aspects of the invention, the method further includes determining the expression level of one or more additional biomarkers (e.g., biomarkers of cancer, e.g., colon cancer or breast cancer). In some embodiments, the one or more additional biomarkers is selected from the group consisting of: carcinoembryonic antigen (CEA), BRAF, KRAS, Fas-ligand, p53, Ki-67, thymidylate-synthase, dihydropyrimidine dehydrogenase, thymidine phosphorylase, microsatellite instability (MIS), and 18q allelic loss of heterozygosity (LOH18q). In certain embodiments, an elevated level of the one or more additional biomarkers indicates that the subject is responsive to the treatment.

In some embodiments of any of the aspects of the invention, the method further includes, prior to the determining of (a) or (b), amplification of the biomarkers from the one or more biological samples. In some embodiments, the method further includes, prior to the determining of (a) or (b), reverse transcription of the biomarkers from the one or more biological samples. In certain embodiments, the product of the amplification or the reverse transcription is cDNA.

In some embodiments of any of the aspects of the invention, the one or more biological samples includes cDNA.

In some embodiments of any of the aspects of the invention, the levels of expression are determined using a microarray or sequencing. In some embodiments, the microarray includes a plurality of nucleic acid probes. In certain embodiments, one or more of the nucleic acid probes (e.g., each of the nucleic acid probes) are configured to hybridize to a target RNA molecule or a target cDNA molecule (e.g., an RNA or DNA (e.g., cDNA) molecule corresponding to one or more of the biomarkers of sensitivity and/or resistance of any one or more of Tables 1-12). In particular embodiments, the one or more of the nucleic acid probes (e.g., each of the nucleic acid probes) includes a sequence having at least, e.g., 75%, 85%, 90%, 95%, 98%, 99%, or 100% sequence identity to a continuous sequence (e.g., a sequence of at least 5, 10, 15, 20, or more nucleic acids in length; such as, e.g., 15 nucleic acids in length) within the target nucleic acid molecule (e.g., a target RNA or DNA (e.g., cDNA) molecule, such as a molecule having the sequence of one or more of the biomarkers of sensitivity and/or resistance of of any one or more of Tables 1-12). In other embodiments, the one or more of the nucleic acid probes (e.g., each of the nucleic acid probes) includes a sequence having at least, e.g., 75%, 85%, 90%, 95%, 98%, 99%, or 100% sequence identity to the complement of a continuous sequence (e.g., a sequence of at least 5, 10, 15, 20, or more nucleic acids in length; such as, e.g., 15 nucleic acids in length) within the target nucleic acid molecule (e.g a target RNA or DNA (e.g., cDNA) molecule, such as a molecule having the sequence of one or more of the biomarkers of sensitivity and/or resistance of any one or more of Tables 1-12). In specific embodiments, each of the target RNA molecules includes at least one of the biomarkers (e.g., an RNA molecule encoding a biomarker protein or transcribed from a biomarker gene). In alternate embodiments, each of the target cDNA molecules is derived from at least one of the biomarkers (e.g., a cDNA reverse-transcribed from a biomarker RNA molecule or having a substantially identical nucleotide sequence to the coding sequence of a biomarker gene).

In some embodiments, each of the nucleic acid probes has a length of, e.g., about 5 nucleotides (nt), 10 nt, 15 nt, 20 nt, 25 nt, 30 nt, 50 nt, 75 nt, 100 nt, 150 nt, or 200 nt (e.g., at least 15 nt). In various embodiments, the nucleic acid probes are single-stranded. In certain embodiments, the nucleic acid probes include DNA, cDNA, RNA, a nucleic acid analog, or a combination thereof.

In some embodiments, the nucleic acid probes are labeled. In certain embodiments, each of the nucleic acid probes is labeled with at least one of a dye molecule, fluorescent molecule, small molecule, nucleic acid barcode, or polypeptide. In particular embodiments, the label is a non-naturally occurring label.

In some embodiments, the microarray is an Almac array. In alternate embodiments, the microarray is an Affymetrix array.

In some embodiments, the sequencing is performed by RNA-Seq. In certain embodiments, the sequencing is performed by 454 pyrosequencing, Illumina sequencing by synthesis, SOLiD sequencing, Ion Torrent sequencing, or PacBio RS sequencing. In particular embodiments, the sequencing includes labeling the one or more biological samples with a plurality of non-naturally occurring labels. In specific embodiments, each of the non-naturally occurring labels are selected from the group consisting of a dye molecule, fluorescent molecule, small molecule, nucleic acid barcode, and polypeptide.

In some embodiments of any of the aspects of the invention, the levels of expression of the one or more biomarkers of sensitivity and/or the levels of expression of the one or more biomarkers of resistance are determined using a NanoString nCounter system.

In some embodiments of any of the aspects of the invention, the determining step (a) and the determining step (b) are performed using the same biological sample. In some embodiments, the determining step (a) and the determining step (b) are performed using different biological samples. In various embodiments, one or more of the biological samples is formalin-fixed paraffin embedded (FFPE) tissue. In some embodiments, one or more of the biological samples is fresh frozen tissue. In certain embodiments, the one or more of the biological samples is obtained from a tumor. In particular embodiments, the one or more of the biological samples includes a tumor biopsy.

In some embodiments of any of the aspects of the invention, the level of expression of the biomarkers of sensitivity and/or the biomarkers of resistance is determined using a device or a kit (e.g., a device or a kit as described herein).

In some embodiments of any of the aspects of the invention, the subject is suffering from cancer or has a predisposition to cancer. In certain embodiments, a cancer has been resected from the subject.

In some embodiments, the cancer is selected from the group consisting of: colorectal cancer, leukemia (e.g., acute myeloid leukemia, acute lymphoid leukemia, chronic myeloid leukemia, chronic lymphocytic leukemia, acute myeloblastic leukemia, acute promyelocytic leukemia, acute myelomonocytic leukemia, acute monocytic leukemia, acute erythroleukemia, or chronic leukemia), myeloma (e.g., multiple myeloma), myelodysplastic syndrome, lymphoma (e.g., diffuse large B-cell lymphoma, cutaneous T-cell lymphoma, peripheral T-cell lymphoma, Hodgkin's lymphoma, non-Hodgkin's lymphoma, Waldenstrom's macroglobulinemia, or lymphocytic lymphoma), cervical cancer, prostate cancer, esophageal cancer, melanoma, glioma (e.g., oligodendroglioma), pancreatic cancer (e.g., adenosquamous carcinoma, signet ring cell carcinoma, hepatoid carcinoma, colloid carcinoma, islet cell carcinoma, or pancreatic neuroendocrine carcinoma), ovarian cancer (e.g., ovarian adenocarcinoma or embryonal carcinoma), gastrointestinal stromal tumor, sarcoma (e.g., fibrosarcoma, myxosarcoma, liposarcoma, chondrosarcoma, osteogenic sarcoma, angiosarcoma, endotheliosarcoma, lymphangiosarcoma, lymphangioendotheliosarcoma, leiomyosarcoma, Ewing's sarcoma, or rhabdomyosarcoma), breast cancer, ER-positive cancer, bladder cancer, head and neck cancer (e.g., squamous cell carcinoma of the head and neck), lung cancer (e.g., non-small cell lung carcinoma, large cell carcinoma, bronchogenic carcinoma, or papillary adenocarcinoma), metastatic cancer, oral cavity cancer, uterine cancer, testicular cancer (e.g., seminoma or embryonal carcinoma), skin cancer (e.g., squamous cell carcinoma or basal cell carcinoma), thyroid cancer (e.g., papillary carcinoma or medullary carcinoma), brain cancer (e.g., astrocytoma or craniopharyngioma), stomach cancer, intra-epithelial cancer, bone cancer, biliary tract cancer, eye cancer, liver cancer (e.g., hepatocellular carcinoma or hepatoma), larynx cancer, kidney cancer (e.g., renal cell carcinoma or Wilms tumor), gastric cancer, blastoma (e.g., nephroblastoma, medulloblastoma, hemangioblastoma, neuroblastoma, or retinoblastoma), polycythemia vera, chordoma, synovioma, mesothelioma, adenocarcinoma, sweat gland carcinoma, sebaceous gland carcinoma, cystadenocarcinoma, bile duct carcinoma, choriocarcinoma, epithelial carcinoma, ependymoma, pinealoma, acoustic neuroma, schwannoma, meningioma, pituitary adenoma, nerve sheath tumor, cancer of the small intestine, cancer of the endocrine system, cancer of the penis, cancer of the urethra, cutaneous or intraocular melanoma, a gynecologic tumor, solid tumors of childhood, and neoplasms of the central nervous system.

In certain embodiments, the cancer is colorectal cancer. In particular embodiments, the colorectal cancer is colon cancer or rectal cancer. In specific embodiments, the colon cancer is selected from the group consisting of: adenocarcinoma, gastrointestinal carcinoid tumor, primary colorectal lymphoma, leiomyosarcoma, colorectal melanoma, and squamous cell carcinoma. In one embodiment, the colon cancer is adenocarcinoma. In particular embodiments, the colon cancer is Stage 0, Stage I, Stage II, Stage III, or Stage IV colon cancer. In one embodiment, the colon cancer is Stage II colon cancer. In another embodiment, the colon cancer is Stage III colon cancer.

In certain embodiments, the cancer is breast cancer. In particular embodiments, the breast cancer is medullary carcinoma. In specific embodiments, the breast cancer is Stage 0, Stage I, Stage II, Stage III, or Stage IV breast cancer.

In a tenth aspect, the invention features a method of assessing the responsiveness of a subject to treatment with 5-FU, irinotecan, or oxaliplatin by:

(a) determining a level of expression of one or more biomarkers of sensitivity in one or more biological samples obtained from the subject; or

(b) determining a level of expression of one or more biomarkers of resistance in one or more biological samples obtained from the subject; in which the one or more biomarkers of sensitivity includes a gene determined to have at least a 0.25 Pearson correlation between the mRNA expression level of the gene and growth inhibition of a cultured cell exposed to the drug, and/or the one or more biomarkers of resistance includes a gene determined to have at least a −0.25 Pearson correlation between the mRNA expression level of the gene and growth inhibition of a cultured cell exposed to the drug; and

in which the levels of expression of the biomarker of sensitivity or the biomarker of resistance indicate whether the subject is responsive to the treatment.

In some embodiments of any of the aspects of the invention, responsiveness (e.g., sensitivity or resistance) to treatment with 5-FU also indicates responsiveness to treatment with a 5-FU analog (e.g., a prodrug, derivative, metabolite, or enantiomer of 5-FU). In certain embodiments, if a subject is determined to be sensitive to 5-FU, then the subject is also determined to be sensitive to a 5-FU analog. In other embodiments, if a subject is determined to be resistant to 5-FU, then the subject is also determined to be resistant to a 5-FU analog. In particular embodiments, the 5-FU analog is a 5-FU prodrug (e.g., capecitabine or tegafur).

In some embodiments of any of the aspects of the invention, responsiveness (e.g., sensitivity or resistance) to treatment with irinotecan also indicates responsiveness to treatment with an irinotecan analog (e.g., a prodrug, derivative, metabolite, or enantiomer of irinotecan). In certain embodiments, if a subject is determined to be sensitive to irinotecan, then the subject is also determined to be sensitive to an irinotecan analog. In other embodiments, if a subject is determined to be resistant to irinotecan, then the subject is also determined to be resistant to an irinotecan analog.

In some embodiments of any of the aspects of the invention, responsiveness (e.g., sensitivity or resistance) to treatment with oxaliplatin also indicates responsiveness to treatment with an oxaliplatin analog (e.g., a prodrug, derivative, metabolite, or enantiomer of oxaliplatin). In certain embodiments, if a subject is determined to be sensitive to oxaliplatin, then the subject is also determined to be sensitive to an oxaliplatin analog. In other embodiments, if a subject is determined to be resistant to oxaliplatin, then the subject is also determined to be resistant to an oxaliplatin analog.

In an eleventh aspect, the invention features a device for detecting the level of expression of one or more biomarkers (e.g., biomarkers of sensitivity and/or resistance to a target drug, e.g., 5-FU, irinotecan, or oxaliplatin, or derivatives, analogs, or prodrugs thereof), which includes:

at least one single-stranded nucleic acid having at least 75% sequence identity (e.g., 75%, 85%, 90%, 95%, 98%, 99%, or 100% sequence identity) to a nucleic acid sequence complementary or identical to at least 5 consecutive nucleotides of one or more biomarkers selected from the biomarkers of Table 1 or 2;

in which at least one single-stranded nucleic acid is sufficient for the detection of the level of expression of the one or more biomarkers, and the device allows for specific hybridization between the single-stranded nucleic acid and the one or more biomarkers or complementary nucleic acids thereof.

In a twelfth aspect, the invention features a device configured to perform a method (e.g., a method of assessing the responsiveness of a subject to treatment with, e.g., 5-FU, irinotecan, or oxaliplatin; or a method of treating a subject) described herein.

In a thirteenth aspect, the invention features a kit including:

(i) reagents for collecting nucleic acids from a biological sample, for example, a biological sample obtained from a subject (e.g., a subject suffering from or susceptible to cancer, e.g., colon cancer or breast cancer);

(ii) reagents for amplifying the nucleic acids to produce an amplified sample; and/or

(iii) at least one device of the present invention.

In a fourteenth aspect, the invention features a method for identifying biomarkers of sensitivity or resistance to a target drug by:

(i) contacting a first cell with an effective amount of the target drug;

(ii) incubating the first cell and a second cell not contacted with an effective amount of the target drug under identical conditions in parallel;

(iii) measuring the growth inhibition values (G150) for the first cell and the second cell;

(iv) obtaining the gene expression profiles (e.g., using a microarray, sequencing, and/or a NanoString nCounter system) for the first cell and the second cell; and

(v) determining a correlation (e.g., a Pearson correlation) comparing the gene expression profiles for the first cell and the second cell with respect to their G150 values;

in which the correlation between the expression level of a gene from the gene expression profiles of the first cell and the second cell and the G150 values for the first cell and the second cell being, e.g., at least 0.25 indicates that the gene is a biomarker of sensitivity, and the correlation between the expression level of a gene from the gene expression profiles of the first cell and the second cell and the G150 values for the first cell and the second cell being, e.g., −0.25 or less indicates that the gene is a biomarker of resistance.

In all aspects of the invention, the level of expression of the biomarkers of sensitivity to 5-FU can be determined using a probe capable of detecting a nucleic acid having the sequence of at least one of SEQ ID NOs. 1-93 and the sequences listed in Table 7. In some embodiments, the probe includes a sequence including at least 5 (e.g., at least 15) continuous nucleotides and at least 75% identity (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) to a sequence identical to or complementary to at least one of SEQ ID NOs. 1-93 and the sequences listed in Table 7.

In all aspects of the invention, the level of expression of the biomarkers of resistance to 5-FU can be determined using a probe capable of detecting a nucleic acid having the sequence of at least one of SEQ ID NOs. 94-208 and the sequences listed in Table 8. In some embodiments, the probe includes a sequence including at least 5 (e.g., at least 15) continuous nucleotides and at least 75% identity (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) to a sequence identical to or complementary to at least one of SEQ ID NOs. 94-208 and the sequences listed in Table 8.

In all aspects of the invention, the level of expression of the biomarkers of sensitivity to irinotecan can be determined using a probe capable of detecting a nucleic acid having the sequence of at least one of SEQ ID NOs. 209-353 and the sequences listed in Table 9. In some embodiments, the probe includes a sequence including at least 5 (e.g., at least 15) continuous nucleotides and at least 75% identity (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) to a sequence identical to or complementary to at least one of SEQ ID NOs. 209-353 and the sequences listed in Table 9.

In all aspects of the invention, the level of expression of the biomarkers of resistance to irinotecan can be determined using a probe capable of detecting a nucleic acid having the sequence of at least one of SEQ ID NOs. 354-398 and the sequences listed in Table 10. In some embodiments, the probe includes a sequence including at least 5 (e.g., at least 15) continuous nucleotides and at least 75% identity (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) to a sequence identical to or complementary to at least one of SEQ ID NOs. 354-398 and the sequences listed in Table 10.

In all aspects of the invention, the level of expression of the biomarkers of sensitivity to oxaliplatin can be determined using a probe capable of detecting a nucleic acid having the sequence of at least one of SEQ ID NOs. 399-578 and the sequences listed in Table 11. In some embodiments, the probe includes a sequence including at least 5 (e.g., at least 15) continuous nucleotides and at least 75% identity (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) to a sequence identical to or complementary to at least one of SEQ ID NOs. 399-578 and the sequences listed in Table 11.

In all aspects of the invention, the level of expression of the biomarkers of resistance to oxaliplatin can be determined using a probe capable of detecting a nucleic acid having the sequence of at least one of SEQ ID NOs. 579-826 and the sequences listed in Table 12. In some embodiments, the probe includes a sequence including at least 5 (e.g., at least 15) continuous nucleotides and at least 75% identity (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) to a sequence identical to or complementary to at least one of SEQ ID NOs. 579-826 and the sequences listed in Table 12.

In all aspects of the invention, the expression level of NT5E can be determined using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 94, 1015, 1016, 1683, 2064, 2207, 2316, 2446, 2714, and 2778, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to, or complementary to, e.g., SEQ ID NO. 94, 1015, 1016, 1683, 2064, 2207, 2316, 2446, 2714, or 2778.

In all aspects of the invention, the expression level of CNN3 can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 95, 1157, 1476, or 1847, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to, or complementary to, e.g., SEQ ID NO. 95, 1157, 1476, or 1847.

In all aspects of the invention, the expression level of ACTN1 can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 96, 934, 2203, 2469, 2737, 2816, or 2817, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to, or complementary to, e.g., SEQ ID NO. 96, 934, 2203, 2469, 2737, 2816, or 2817.

In all aspects of the invention, the expression level of FLNA can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 97, 1387, 1490, 1542, 1621, 1773, 1867, 1902, 1960, 2048, 2051, 2347, or 2348, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 97, 1387, 1490, 1542, 1621, 1773, 1867, 1902, 1960, 2048, 2051, 2347, or 2348.

In all aspects of the invention, the expression level of ATP2B4 can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 98, 1498, 1845, 2056, 2284, 2285, 2523, or 2627, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 98, 1498, 1845, 2056, 2284, 2285, 2523, or 2627.

In all aspects of the invention, the expression level of APRT can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 1 or 1201, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 1 or 1201.

In all aspects of the invention, the expression level of GSR can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 2, 907, 1148, 1722, or 2750, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 2, 907, 1148, 1722, or 2750.

In all aspects of the invention, the expression level of TUFM can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 3 or 1146, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 3 or 1146.

In all aspects of the invention, the expression level of MRPS2 can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 4 or 839, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 4 or 839.

In all aspects of the invention, the expression level of MTHFD2 can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 5 or 1189, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 5 or 1189.

In all aspects of the invention, the expression level of PRF1 can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 209, 2314, 2315, or 2881, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 209, 2314, 2315, or 2881.

In all aspects of the invention, the expression level of GZMB can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 210, 1681, or 1682, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 210, 1681, or 1682.

In all aspects of the invention, the expression level of PTPRC can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 211, 212, 1020, 1632, 1675, 1998, 1999, 2535, 2636, or 2797, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 211, 212, 1020, 1632, 1675, 1998, 1999, 2535, 2636, or 2797.

In all aspects of the invention, the expression level of PTPRCAP can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 213, 1645, or 1646, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 213, 1645, or 1646.

In all aspects of the invention, the expression level of CCND1 can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 354, 1592, 1593, 1679, 1727, 1752, 1817, 2013, or 2640, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 354, 1592, 1593, 1679, 1727, 1752, 1817, 2013, or 2640.

In all aspects of the invention, the expression level of LGALS3 can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 355, 1299, 1334, 1335, or 2069, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 355, 1299, 1334, 1335, or 2069.

In all aspects of the invention, the expression level of INPP4B can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 356, 919, 1453, 1616, 1617, 2199, 2386, 2625, or 2626, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 356, 919, 1453, 1616, 1617, 2199, 2386, 2625, or 2626.

In all aspects of the invention, the expression level of TMEM97 can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 357, 966, 2532, or 2566, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 357, 966, 2532, or 2566.

In all aspects of the invention, the expression level of TCF7L2 can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 358, 955, 1536, 1852, 2081, 2099, 2171, 2192, 2219, 2539, 2575, 2665, or 2880, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 358, 955, 1536, 1852, 2081, 2099, 2171, 2192, 2219, 2539, 2575, 2665, or 2880.

In all aspects of the invention, the expression level of MRPL16 can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 399 or 1144, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 399 or 1144.

In all aspects of the invention, the expression level of ANP32A can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 400, 1921, 2357, 2358, 2736, 2799, or 2800, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 400, 1921, 2357, 2358, 2736, 2799, or 2800.

In all aspects of the invention, the expression level of SRSF2 can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of, e.g., SEQ ID NO. 401, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 401.

In all aspects of the invention, the expression level of PDSS1 can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 402, 862, or 2058, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 402, 862, or 2058.

In all aspects of the invention, the expression level of PRIM1 can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 403, 2266, or 2267, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 403, 2266, or 2267.

In all aspects of the invention, the expression level of LPP can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 579, 984, 1031, 1437, 1693, 1731, 1828, 1831, 1872, 2040, 2063, 2104, 2109, 2119, 2123, 2160, 2197, 2400, 2401, 2618, 2784, 2852, or 2853, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 579, 984, 1031, 1437, 1693, 1731, 1828, 1831, 1872, 2040, 2063, 2104, 2109, 2119, 2123, 2160, 2197, 2400, 2401, 2618, 2784, 2852, or 2853.

In all aspects of the invention, the expression level of RHOC can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of, e.g., SEQ ID NO. 580, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 580.

In all aspects of the invention, the expression level of CAPN2 can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 581, 1521, 1552, 1900, 1965, 2154, 2233, 2234, or 2826, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 581, 1521, 1552, 1900, 1965, 2154, 2233, 2234, or 2826.

In all aspects of the invention, the expression level of FLNA can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 582, 584, 587, 1387, 1490, 1542, 1621, 1773, 1867, 1902, 1960, 2048, 2051, 2347, or 2348, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 582, 584, 587, 1387, 1490, 1542, 1621, 1773, 1867, 1902, 1960, 2048, 2051, 2347, or 2348.

In all aspects of the invention, the expression level of WDR1 can be determined, e.g., using a probe capable of detecting a nucleic acid having the sequence of any one or more of, e.g., SEQ ID NO. 583, 894, 1135, 1136, 1390, 2194, 2335, 2506, 2839, or 2862, or a complement thereof. In some embodiments, the probe includes a sequence having at least 5 (e.g., at least 15) continuous nucleotides and at least 75% (e.g., 75%, 80%, 85%, 90%, 95%, 99%, or 100%) identity to a sequence identical to or complementary to, e.g., SEQ ID NO. 583, 894, 1135, 1136, 1390, 2194, 2335, 2506, 2839, or 2862.

Definitions

As used herein, “5-fluorouracil,” “fluorouracil,” and “5-FU” refer to a compound having the structure of Formula (I), or to formulations containing such a compound.

A “5-FU analog” means any therapeutic agent having a structure similar to the compound of Formula (I) and/or biological activity the same or similar to that of the compound of Formula (I), for example, prodrugs (e.g., capecitabine and tegafur), derivatives, metabolites, and enantiomers of Formula (I). If a specific formulation of 5-FU or a 5-FU analog is meant, that formulation is referenced by its specific name.

The term “irinotecan,” as used herein, refers to a compound having the structure of Formula (II), or to formulations containing such a compound.

An “irinotecan analog” means any therapeutic agent having a structure similar to the compound of Formula (II) and/or biological activity the same or similar to that of the compound of Formula (II), for example, prodrugs, derivatives, metabolites, and enantiomers of Formula (II). If a specific formulation of irinotecan or an irinotecan analog is meant, that formulation is referenced by its specific name.

By “oxaliplatin” is meant a compound having the structure of Formula (III), or to formulations containing such a compound.

An “oxaliplatin analog” means any therapeutic agent having a structure similar to the compound of Formula (III) and/or biological activity the same or similar to that of the compound of Formula (III), for example, prodrugs, derivatives, metabolites, and enantiomers of Formula (III). If a specific formulation of oxaliplatin or an oxaliplatin analog is meant, that formulation is referenced by its specific name.

The terms “capecitabine” and “Xeloda,” as used herein, mean a compound having the structure of Formula (IV), or to formulations containing such a compound.

Capecitabine compounds can be, e.g., metabolized into 5-FU in the body and can thus be used as a prodrug for 5-FU, such as for the treatment of cancers, e.g., colon cancer or breast cancer.

The term “tegafur,” as used herein, means a compound having the structure of Formula (V), or to formulations containing such a compound.

Tegafur compounds can be, e.g., metabolized into 5-FU in the body and can thus be used as a prodrug for 5-FU. Tegafur can be used according the methods of the invention, for example, as a component of the combination drug tegafur/uracil for the treatment of, e.g., cancers (e.g., colon cancer or breast cancer).

The terms “responsive” and “responsiveness,” as used herein with respect to a subject's responsiveness to a treatment, e.g., treatment with a compound, such as an anti-cancer agent (e.g., 5-FU, irinotecan, or oxaliplatin), or treatment with radiation, refer to the likelihood that the treatment has (e.g., induces) a desired effect, or alternatively refers to the strength of a desired effect caused or induced by the treatment in a cell, a tumor, or subject (e.g., a mammal, such as a human). For example, the desired effect can include inhibition of the growth of a cell, e.g., a cancer cell, in vitro or in a tumor, person, or living organism by more than 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, or 100% relative to the growth of a cell not exposed to the treatment. The desired effect can also include reduction in tumor mass by, e.g., about 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, or 100%. Responsiveness to treatment may be determined by a cell-based assay that measures the growth of treated cells as a function of the cells' absorbance of an incident light beam as used to perform the NCI60 assays described herein. In this example, lesser absorbance indicates lesser cell growth, and thus, sensitivity to the treatment. A greater reduction in growth indicates more sensitivity to the treatment. According to the present invention, “responsiveness” is a measure of the sensitivity or resistance of a subject to a treatment, e.g., for cancer, for example, by treatment with a target drug (e.g., 5-FU, irinotecan, and oxaliplatin). A “sensitive” or “responsive” subject is one in which the treatment will produce the desired effect (e.g., as defined above), for example, as compared to a control subject (e.g., the population median). A “resistant” subject is one in which the treatment will have no effect, will produce an effect less than that observed in a control subject (e.g., the population median), or will produce an effect only if the treatment is administered in an amount greater than would be applied to a control subject (e.g., the population median).

A “sensitivity biomarker” and “biomarker of sensitivity” to a target drug, as used herein, mean a gene or gene product for which the expression level (e.g., mRNA expression level or protein expression level) has been correlated to higher subject sensitivity to treatment with the target drug (e.g., 5-FU, irinotecan, oxaliplatin, or combinations thereof). In certain embodiments, an increased level of expression of the sensitivity biomarker in a biological sample obtained from a subject, relative to a control subject (e.g. the population median), indicates that the subject is sensitive to the treatment. For example, biomarkers of sensitivity to 5-FU include those listed in Table 1, biomarkers of sensitivity to irinotecan include those listed in Table 3, and biomarkers of sensitivity to oxaliplatin include those listed in Table 5.

A “resistance biomarker” and “biomarker of resistance ” to a target drug, as used herein, mean a gene or gene product for which the expression level (e.g., mRNA expression level or protein expression level) has been correlated to reduced subject sensitivity to treatment with the target drug (e.g., 5-FU, irinotecan, oxaliplatin, or combinations thereof). In certain embodiments, an increased level expression of the resistance biomarker in a biological sample obtained from a subject, relative to a control subject (e.g. the population median), indicates that the subject is resistant to the treatment. For example, biomarkers of resistance to 5-FU include those listed in Table 2, biomarkers of resistance to irinotecan include those listed in Table 4, and biomarkers of resistance to oxaliplatin include those listed in Table 6.By “gene” is meant, e.g., a coding or noncoding gene whose activity can be determined by measuring the produced RNA. Examples include protein coding genes, microRNAs, small nuclear RNAs and other RNAs with catalytic, regulatory or coding properties.

“Compound” as used herein means a chemical or biological substance, e.g., a drug, a protein, an antibody, or an oligonucleotide, which may be used to treat a disease or which has biological activity in vivo or in vitro. Compounds may or may not be approved by the U.S. Food and Drug Administration (FDA). Compounds of the invention include, e.g., anti-cancer agents (e.g., chemotherapy agents) that may inhibit cancer growth. Anti-cancer agents (chemotherapy agents) include 5-FU, capecitabine, tegafur, irinotecan, oxaliplatin, fulvestrant (also known under the name FASLODEX®), gefitinib (IRESSA®), ERLOTINIB (TARCEVA®), tamoxifen, trastuzumab (HERCEPTIN®), cisplatin, belinostat, and vincristine.

By “target drug” is meant a drug or combination of drugs that can be used to treat a subject, e.g., a patient suffering from or susceptible to a disease, disorder, or condition of interest (e.g., a cancer, such as colon cancer). Different subjects may have varying responsiveness (e.g., sensitivity and/or resistance) to a target drug, which can be assessed according to the methods and/or using the devices of the invention. Exemplary target drugs include 5-FU, irinotecan, and oxaliplatin, as well as prodrugs, derivatives, metabolites, enantiomers, analogs, and combinations thereof.

By “biomarker” and “biomarker gene” is meant a gene (e.g., a protein-coding DNA, mRNA, microRNA, or noncoding RNA) in a cell, the expression of which correlates to responsiveness (e.g., sensitivity or resistance) of the cell (and thus the patient containing the cell or from which the cell was obtained) to a treatment (e.g., exposure to a compound of the invention).

The terms “expression level” and “level of expression,” as used herein, refer to the amount of a gene product in a cell, tissue, biological sample, organism, or subject, e.g., amounts of DNA, RNA, or proteins, amounts of modifications of DNA, RNA, or protein, such as splicing, phosphorylation, acetylation, or methylation, or amounts of activity of DNA, RNA, or proteins associated with a given gene.

“Microarray” as used herein means a device employed by any method that quantifies one or more subject oligonucleotides, e.g., DNA or RNA, or analogs thereof, at a time. One exemplary class of microarrays consists of DNA probes attached to a glass or quartz surface. For example, many microarrays, including those made by Affymetrix, use several probes for determining the expression of a single gene. The DNA microarray may contain oligonucleotide probes that may be, e.g., full-length cDNAs complementary to an RNA or cDNA fragments that hybridize to part of an RNA. Exemplary RNAs include mRNA, miRNA, and miRNA precursors. Exemplary microarrays also include a “nucleic acid microarray” having a substrate-bound plurality of nucleic acids, hybridization to each of the plurality of bound nucleic acids being separately detectable. The substrate may be solid or porous, planar or non-planar, unitary or distributed. Exemplary nucleic acid microarrays include all of the devices so called in Schena (ed.), DNA Microarrays: A Practical Approach (Practical Approach Series), Oxford University Press (1999); Nature Genet. 21(1)(suppl.):1-60 (1999); Schena (ed.), Microarray Biochip: Tools and Technology, Eaton Publishing Company/BioTechniques Books Division (2000). Additionally, exemplary nucleic acid microarrays include substrate-bound plurality of nucleic acids in which the plurality of nucleic acids are disposed on a plurality of beads, rather than on a unitary planar substrate, as is described, inter alia, in Brenner et al., Proc. Natl. Acad. Sci. USA 97(4):1665-1670 (2000). Examples of nucleic acid microarrays may be found in U.S. Pat. Nos. 6,391,623, 6,383,754, 6,383,749, 6,380,377, 6,379,897, 6,376,191, 6,372,431, 6,351,712 6,344,316, 6,316,193, 6,312,906, 6,309,828, 6,309,824, 6,306,643, 6,300,063, 6,287,850, 6,284,497, 6,284,465, 6,280,954, 6,262,216, 6,251,601, 6,245,518, 6,263,287, 6,251,601, 6,238,866, 6,228,575, 6,214,587, 6,203,989, 6,171,797, 6,103,474, 6,083,726, 6,054,274, 6,040,138, 6,083,726, 6,004,755, 6,001,309, 5,958,342, 5,952,180, 5,936,731, 5,843,655, 5,814,454, 5,837,196, 5,436,327, 5,412,087, 5,405,783, the disclosures of which are incorporated herein by reference in their entireties. Exemplary microarrays may also include “peptide microarrays” or “protein microarrays” having a substrate-bound plurality of polypeptides, the binding of a oligonucleotide, a peptide, or a protein to each of the plurality of bound polypeptides being separately detectable. Alternatively, the peptide microarray, may have a plurality of binders, including but not limited to monoclonal antibodies, polyclonal antibodies, phage display binders, yeast 2 hybrid binders, aptamers, which can specifically detect the binding of specific oligonucleotides, peptides, or proteins. Examples of peptide arrays may be found in WO 02/31463, WO 02/25288, WO 01/94946, WO 01/88162, WO 01/68671, WO 01/57259, WO 00/61806, WO 00/54046, WO 00/47774, WO 99/40434, WO 99/39210, WO 97/42507 and U.S. Pat. Nos. 6,268,210, 5,766,960, 5,143,854, the disclosures of which are incorporated herein by reference in their entireties.

“Complement” of a nucleic acid sequence or a “complementary” nucleic acid sequence as used herein refers to an oligonucleotide which is in “antiparallel association” when it is aligned with the nucleic acid sequence such that the 5′ end of one sequence is paired with the 3′ end of the other. Nucleic acids are referred to as being “complementary” if they contain nucleotides or nucleotide homologues that can form hydrogen bonds according to Watson-Crick base-pairing rules (e.g., G with C, A with T or A with U) or other hydrogen bonding motifs such as for example diaminopurine with T, 5-methyl C with G, 2-thiothymidine with A, inosine with C, pseudoisocytosine with G, etc. Anti-sense RNA may be complementary to other oligonucleotides, e.g., mRNA. A complementary nucleic acid sequence may include non-naturally-occurring bases, e.g., inosine and 7-deazaguanine. When complementary nucleic acid sequences form a stable duplex, they are said to be “hybridized.” “Complementarity” may not be perfect; stable duplexes of complementary nucleic acids may contain mismatched base pairs or unmatched bases. Those skilled in the art of nucleic acid technology can determine duplex stability empirically considering a number of variables including, for example, the length of the oligonucleotide, percent concentration of cytosine and guanine bases in the oligonucleotide, ionic strength, and incidence of mismatched base pairs.

To “inhibit growth” and “inhibition of growth,” as used herein, mean causing a reduction in cell growth in vivo or in vitro by about, e.g., 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, 95%, or 99% or more, as evident by a reduction in the size or number of cells exposed to a treatment (e.g., exposure to a compound), relative to the size or number of cells in the absence of the treatment. Growth inhibition may be the result of a treatment that induces apoptosis in a cell, induces necrosis in a cell, inhibits cell proliferation and/or cell cycle progression, disrupts cellular metabolism, induces cell lysis, or induces some other mechanism that reduces the size or number of cells.

By “NCI60” is meant a panel of 60 cancer cell lines from lung, colon, breast, ovarian, leukemia, renal, melanoma, prostate and brain cancers including the following cancer cell lines: NSCLC_NCIH23, NSCLC_NCIH522, NSCLC_A549ATCC, NSCLC_EKVX, NSCLC_NCIH226, NSCLC_NCIH332M, NSCLC_H460, NSCLC_HOP62, NSCLC_HOP92, COLON_HT29, COLON_HCC-2998, COLON_HCT116, COLON_SW620, COLON_COL0205, COLON_HCT15, COLON_KM12, BREAST_MCF7, BREAST_MCF7ADRr, BREAST_MDAMB231, BREAST_HS578T, BREAST_MDAMB435, BREAST_MDN, BREAST_BT549, BREAST_T47D, OVAR_OVCAR3, OVAR_OVCAR4, OVAR_OVCAR5, OVAR_OVCAR8, OVAR_IGROV1, OVAR_SKOV3, LEUK_CCRFCEM, LEUK_K562, LEUK_MOLT4, LEUK_HL60, LEUK_RPMI8266, LEUK_SR, RENAL_UO31, RENAL_SN12C, RENAL_A498, RENAL_CAKI1, RENAL_RXF393, RENAL_7860, RENAL_ACHN, RENAL_TK10, MELAN_LOXIMVI, MELAN_MALME3M, MELAN_SKMEL2, MELAN_SKMEL5, MELAN_SKMEL28, MELAN_M14, MELAN_UACC62, MELAN_UACC257, PROSTATE_PC3, PROSTATE_DU145, CNS_SNB19, CNS_SNB75, CNS_U251, CNS_SF268, CNS_SF295, and CNS_SF539.

The terms “biological sample” and “sample,” as used herein, refer to any specimen (e.g., cells, tissue (e.g., a tissue sample obtained by biopsy, such as a tumor biopsy), blood, serum, plasma, urine, sputum, cerebrospinal fluid, lymph tissue or fluid, or pancreatic fluid) taken from a subject. In certain embodiments, the biological sample is taken from a portion of the body affected by a cancer (e.g., a biopsy). Biopsy (e.g., colorectal cancer biopsy, breast cancer biopsy, gastrointestinal malignancy biopsy, head and neck cancer biopsy, or ovarian cancer biopsy) may involve fine needle aspiration biopsy, core needle biopsy (e.g., stereotactic core needle biopsy, vacuum-assisted core biopsy, or magnetic resonance imaging (MRI) guided biopsy), or surgical biopsy (e.g., incisional biopsy or excisional biopsy). In certain embodiments, the biological sample is obtained from a tumor (e.g., a tumor biopsy). The sample may undergo additional purification and processing, for example, to remove cell debris and other unwanted molecules. Additional processing may further involve amplification, e.g., using PCR (RT-PCR). The standard methods of sample purification, such as removal of unwanted molecules, are known in the art.

The terms “effective amount,” “amount effective to,” and “therapeutically effective amount,” as used interchangeably herein, refer to an amount of an anti-cancer agent (e.g., 5-FU, irinotecan, or oxaliplatin) sufficient to produce a desired result, such as complete response (CR) of the patient having a cancer, partial response (PR) of the patient having a cancer, or stable disease (SD) in the patient having a cancer. The desirable response criteria (CR, PR, or SD) are well-known in the art, see, e.g., Response Evaluation Criteria in Solid Tumors (RECIST).

The terms “patient” and “subject,” as used interchangeably herein, refer to any animal (e.g., a mammal, e.g., a human). A subject to be treated or tested for responsiveness to an anti-cancer agent according to the methods described herein may be one who has been diagnosed with a cancer (e.g., colorectal cancer, breast cancer, gastrointestinal malignancy, head and neck cancer, or ovarian cancer). Diagnosis may be performed by any method or technique known in the art, such as self-exam, x-ray (e.g., mammogram), MRI, or biopsy. Non-limiting example of a subject include a human having colon cancer or rectal cancer, or a female (e.g., a postmenopausal female) having a breast cancer (e.g., a hormone receptor positive breast cancer). A subject may have been identified using techniques and methods known in the art. To minimize exposure of a subject to drugs that may not be useful, the subject may be determined as either responsive or non-responsive to a specific anti-cancer agent (e.g., 5-FU, irinotecan, or oxaliplatin) according to the methods of the invention. A “control” or “control subject” refers, for example, to a subject not suffering from or not susceptible to a disease, disorder, or condition treatable or diagnosable with the methods, devices, and/or kits described herein, or to a population median (e.g., a median level measured in a set of subjects not suffering from or not susceptible to a disease, disorder, or condition treatable or diagnosable with the methods, devices, and/or kits described herein).

“Treatment,” “medical treatment,” to “treat,” and “therapy” mean administering or exposing a subject, a cell, or a tumor to, e.g., a compound, such as an anti-cancer agent (e.g., a drug, a protein, an antibody, a nucleic acid, a chemotherapeutic agent, or a radioactive agent), or to some other form of medical intervention used to treat or prevent a disease, disorder, or condition (e.g., surgery, cryotherapy, radiation therapy, or combinations thereof). In certain embodiments, the disease to be treated is cancer or symptoms of cancer. Radiation therapy includes the administration of a radioactive agent to a subject, or exposure of a subject to radiation. The radiation may be generated from sources such as particle accelerators and related medical devices or agents that emit, e.g., X-radiation, gamma radiation, or electron (Beta radiation) beams. A treatment may further include surgery, e.g., to remove a tumor from a subject or living organism.

The terms “cancer” and “cancerous” refer to or describe the physiological condition in mammals that is typically characterized by unregulated cell growth. Included in this definition are benign and malignant cancers. A cancer may include a solid or liquid tumor. By “early stage cancer” or “early stage tumor” is meant a cancer that is not invasive or metastatic or is classified as a Stage 0, I, or II cancer. Exemplary cancers include colorectal cancer (e.g., colon cancer and rectal cancer), leukemia (e.g., acute myeloid leukemia, acute lymphoid leukemia, chronic myeloid leukemia, chronic lymphocytic leukemia, acute myeloblastic leukemia, acute promyelocytic leukemia, acute myelomonocytic leukemia, acute monocytic leukemia, acute erythroleukemia, and chronic leukemia), myeloma (e.g., multiple myeloma), myelodysplastic syndrome, lymphoma (e.g., diffuse large B-cell lymphoma, cutaneous T-cell lymphoma, peripheral T-cell lymphoma, Hodgkin's lymphoma, non-Hodgkin's lymphoma, Waldenstrom's macroglobulinemia, and lymphocytic lymphoma), cervical cancer, prostate cancer, esophageal cancer, melanoma, glioma (e.g., oligodendroglioma), pancreatic cancer (e.g., adenosquamous carcinoma, signet ring cell carcinoma, hepatoid carcinoma, colloid carcinoma, islet cell carcinoma, and pancreatic neuroendocrine carcinoma), ovarian cancer (e.g., ovarian adenocarcinoma or embryonal carcinoma), gastrointestinal stromal tumor, sarcoma (e.g., fibrosarcoma, myxosarcoma, liposarcoma, chondrosarcoma, osteogenic sarcoma, angiosarcoma, endotheliosarcoma, lymphangiosarcoma, lymphangioendotheliosarcoma, leiomyosarcoma, Ewing's sarcoma, and rhabdomyosarcoma), breast cancer (e.g., medullary carcinoma), ER-positive cancer, bladder cancer, head and neck cancer (e.g., squamous cell carcinoma of the head and neck), lung cancer (e.g., non-small cell lung carcinoma, large cell carcinoma, bronchogenic carcinoma, and papillary adenocarcinoma), metastatic cancer, oral cavity cancer, uterine cancer, testicular cancer (e.g., seminoma and embryonal carcinoma), skin cancer (e.g., squamous cell carcinoma, and basal cell carcinoma), thyroid cancer (e.g., papillary carcinoma and medullary carcinoma), brain cancer (e.g., astrocytoma and craniopharyngioma), stomach cancer, intra-epithelial cancer, bone cancer, biliary tract cancer, eye cancer, liver cancer (e.g., hepatocellular carcinoma or hepatoma), larynx cancer, kidney cancer (e.g., renal cell carcinoma and Wilms tumor), gastric cancer, blastoma (e.g., nephroblastoma, medulloblastoma, hemangioblastoma, neuroblastoma, and retinoblastoma), polycythemia vera, chordoma, synovioma, mesothelioma, adenocarcinoma, sweat gland carcinoma, sebaceous gland carcinoma, cystadenocarcinoma, bile duct carcinoma, choriocarcinoma, epithelial carcinoma, ependymoma, pinealoma, acoustic neuroma, schwannoma, meningioma, pituitary adenoma, nerve sheath tumor, cancer of the small intestine, cancer of the endocrine system, cancer of the penis, cancer of the urethra, cutaneous or intraocular melanoma, a gynecologic tumor, solid tumors of childhood, and neoplasms of the central nervous system.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 is a graph grouping predicted sensitivity to 5-FU by indication. Each gray circle represents the predicted 5-FU sensitivity of one patient. Patients are grouped according to indication, and the relative mean predicted sensitivity (black cross) for an indication is related to the relative response rate for that indication. The predictions can only be used for relative comparisons: comparing indications to each other. It cannot be used for absolute predictions of response rate for a given indication. The predictions are normalized to a scale of 0-100 for all 3522 patients in this plot.

FIG. 2 is a graph showing predicted sensitivity to 5-FU in 226 Japanese non-small cell lung cancer (NSCLC) adenocarcinomas according to mutation status. Boxes represent first and third quartiles, and whiskers indicate minimum and maximum values. The dark line indicates the median value.

FIG. 3 is a graph showing predicted sensitivity to 5-FU in 243 breast cancer patients according to receptor status. Boxes represent first and third quartiles, and whiskers indicate minimum and maximum values. The dark line indicates the median value.

FIG. 4 is a graph comparing predicted sensitivity to 5-FU and Afinitor (everolimus) in 243 breast cancer patients.

FIG. 5 is a graph showing disease-free survival of patients predicted sensitive to 5-FU (gray) and patients predicted resistant to 5-FU (black). HR=hazard ratio.

FIG. 6 is a graph showing the predicted sensitivity of colorectal cancer patients to FOLFIRI. CR=complete responders, PR=partial responders, SD=stable disease, PD=progressive disease, CC=correlation coefficient. Boxes represent first and third quartiles, and whiskers indicate minimum and maximum values. The dark line indicates the median value.

FIG. 7 is a graph showing the predicted sensitivity of colorectal cancer patients (responders and non-responders) to FOLFOX. Boxes represent first and third quartiles, and whiskers indicate minimum and maximum values. The dark line indicates the median value.

DETAILED DESCRIPTION OF THE INVENTION

Drug response predictors are assays that, based on a biological sample from a subject, can predict whether the subject will respond to a specific drug or drug combination. The present invention provides drug response predictors and biomarkers useful for assessing the responsiveness of subjects to treatment with one or more specified target drugs of interest, e.g., 5-fluorouracil (5-FU), irinotecan, and/or oxaliplatin, as well as analogs thereof, such as prodrugs (e.g., capecitabine or tegafur), derivatives, metabolites, enantiomers, and combinations thereof. In particular, the invention provides methods useful in determining whether a subject is, e.g., sensitive or resistant to a target drug by, e.g., measuring the expression level (e.g., mRNA or protein expression level) of one or more biomarkers of sensitivity and/or resistance to the drug in a biological sample obtained from the subject. The expression levels of sensitivity biomarkers can then be compared to the expression of, for example, (i) other sensitivity biomarkers, (ii) resistance biomarkers, or (iii) biomarker expression levels in control subjects, to assess the subject's responsiveness to treatment with the target drug. Conversely, the expression levels of resistance biomarkers can be compared to the expression of, for example, (i) other resistance biomarkers, (ii) sensitivity biomarkers, or (iii) biomarker expression levels in control subjects, to assess the subject's responsiveness to treatment with the drug. In certain embodiments, the target drug includes 5-FU (or a prodrug thereof, e.g., capecitabine or tegafur), irinotecan, and/or oxaliplatin. Pre-clinical and clinical validation of drug response predictors have been developed by the present inventors for a number of other drugs (see, e.g., U.S. Pat. No. 8,445,198; PCT Publication No. WO2011/135459; PCT Publication No. WO2012163541; Chen et al., Mol. Cancer Ther. 11(1): 34-44, 2012; Bullinger et al., 2013, presented at ESMO conference 2012; Wang et al., J. National Cancer Inst. 105(17): 1284-91, 2013; Knudsen et al., PLOS ONE, 9(2): e87415, 2014; each of which is incorporated herein in its entirety).

The invention further features devices and kits for determining the expression level of such biomarkers, e.g., arrays of oligonucleotide probes suitable for hybridization to and detection of the biomarkers (e.g., biomarkers of sensitivity or resistance to, for example, 5-FU, irinotecan, and oxaliplatin). Also featured are methods of identifying biomarkers of sensitivity or resistance to a drug based on the correlation of biomarker expression to treatment efficacy, e.g., the growth inhibition of cancer cells. As such, the methods, devices, and kits described herein provide novel and effective means to, e.g., diagnose and/or monitor patient responsiveness to particular drug regimens of interest. Moreover, the methods, devices, and kits of the invention can be used to identify subject subpopulations that are responsive to a drug previously thought to be ineffective for treating disease (e.g., cancer, such as colorectal cancer) in the general population.

Methods of Diagnosis and Monitoring

The invention features diagnostic methods useful for assessing a subject's likely responsiveness to treatment with one or more target drugs (e.g., 5-FU, irinotecan, or oxaliplatin). Such methods can also be used to monitor a subject's responsiveness to such target drugs during or after treatment. In some embodiments, the subject is suffering from or at risk of developing a disease or condition (in particular, cancer, e.g., colorectal cancer), such as a disease or condition treatable with one or more target drugs, such as those described herein.

Indications

The methods, devices, and kits of the invention can be used for diagnosing, prognosing, monitoring, treating, and/or preventing cancer in a subject suffering from, diagnosed with, or susceptible to cancer. Non-limiting examples of cancers that can be diagnosed, prognosed, monitored, treated, or prevented using the present invention include colorectal cancer (e.g., colon cancer and rectal cancer), leukemia (e.g., acute myeloid leukemia, acute lymphoid leukemia, chronic myeloid leukemia, chronic lymphocytic leukemia, acute myeloblastic leukemia, acute promyelocytic leukemia, acute myelomonocytic leukemia, acute monocytic leukemia, acute erythroleukemia, and chronic leukemia), myeloma (e.g., multiple myeloma), myelodysplastic syndrome, lymphoma (e.g., diffuse large B-cell lymphoma, cutaneous T-cell lymphoma, peripheral T-cell lymphoma, Hodgkin's lymphoma, non-Hodgkin's lymphoma, Waldenstrom's macroglobulinemia, and lymphocytic lymphoma), cervical cancer, prostate cancer, esophageal cancer, melanoma, glioma (e.g., oligodendroglioma), pancreatic cancer (e.g., adenosquamous carcinoma, signet ring cell carcinoma, hepatoid carcinoma, colloid carcinoma, islet cell carcinoma, and pancreatic neuroendocrine carcinoma), ovarian cancer (e.g., ovarian adenocarcinoma or embryonal carcinoma), gastrointestinal stromal tumor, sarcoma (e.g., fibrosarcoma, myxosarcoma, liposarcoma, chondrosarcoma, osteogenic sarcoma, angiosarcoma, endotheliosarcoma, lymphangiosarcoma, lymphangioendotheliosarcoma, leiomyosarcoma, Ewing's sarcoma, and rhabdomyosarcoma), breast cancer (e.g., medullary carcinoma), ER-positive cancer, bladder cancer, head and neck cancer (e.g., squamous cell carcinoma of the head and neck), lung cancer (e.g., non-small cell lung carcinoma, large cell carcinoma, bronchogenic carcinoma, and papillary adenocarcinoma), metastatic cancer, oral cavity cancer, uterine cancer, testicular cancer (e.g., seminoma and embryonal carcinoma), skin cancer (e.g., squamous cell carcinoma, and basal cell carcinoma), thyroid cancer (e.g., papillary carcinoma and medullary carcinoma), brain cancer (e.g., astrocytoma and craniopharyngioma), stomach cancer, intra-epithelial cancer, bone cancer, biliary tract cancer, eye cancer, liver cancer (e.g., hepatocellular carcinoma or hepatoma), larynx cancer, kidney cancer (e.g., renal cell carcinoma and Wilms tumor), gastric cancer, blastoma (e.g., nephroblastoma, medulloblastoma, hemangioblastoma, neuroblastoma, and retinoblastoma), polycythemia vera, chordoma, synovioma, mesothelioma, adenocarcinoma, sweat gland carcinoma, sebaceous gland carcinoma, cystadenocarcinoma, bile duct carcinoma, choriocarcinoma, epithelial carcinoma, ependymoma, pinealoma, acoustic neuroma, schwannoma, meningioma, pituitary adenoma, nerve sheath tumor, cancer of the small intestine, cancer of the endocrine system, cancer of the penis, cancer of the urethra, cutaneous or intraocular melanoma, a gynecologic tumor, solid tumors of childhood, and neoplasms of the central nervous system.

In certain embodiments, the cancer is a colon cancer, such as colorectal cancer (e.g., adenocarcinoma, gastrointestinal carcinoid tumor, primary colorectal lymphoma, leiomyosarcoma, colorectal melanoma, and squamous cell carcinoma). The colon cancer can be, for example, a Stage 0, Stage I, Stage II, Stage III, or Stage IV colon cancer. In certain embodiments, the colon cancer is Stage II or Stage III colon cancer. In alternate embodiments, the cancer is a breast cancer, such as medullary carcinoma. The breast cancer can be, for example, a Stage 0, Stage I, Stage II, Stage III, or Stage IV breast cancer.

Target Drugs

The present invention features drug response predictors for drugs of interest (“target drugs”), in which the expression level of one or more of a panel of biomarkers is used to determine a subject's responsiveness (e.g., sensitivity or resistance) to a target drug. A target drug can be useful for treating or preventing a condition, disease, or disorder such as those described herein (e.g., colon cancer). In certain embodiments, the target drug is one previously thought to be ineffective for treating or preventing a condition, disease, or disorder, such as those described herein, in a patient or subpopulation of patients, but which may be effective in certain subject subpopulations (e.g., a subpopulation identifiable by the methods, devices, or kits of the invention). Exemplary target drugs include, but are not limited to, 5-fluorouracil (5-FU), irinotecan, and/or oxaliplatin, as well as analogs thereof, such as prodrugs, derivatives, metabolites, enantiomers, and combinations thereof.

Biomarkers of Drug Responsiveness

Particular subsets of a patient population may be sensitive or resistant to a particular target drug. The present invention provides a set of biomarker genes, the expression levels of which (e.g., as detected in biological samples obtained from a subject, such as a patient in need of treatment) are indicative of sensitivity or resistance to certain target drugs (e.g., 5-FU, irinotecan, or oxaliplatin). Such biomarkers can be identified using methods such as those the inventors have previously described in, e.g., Chen et al. (Mol. Cancer Ther. 11:34-33, 2012), Wang et al. (J. Nat. Cancer Inst. 105: 1284-1291, 2013), and Knudsen et al. (PLoS One, 9: e87415, 2014), each of which are incorporated by reference herein in their entirety. In certain embodiments, an algorithm based on growth inhibition values (GI50) of a cell line (e.g., NCI60 cells) is subjected to treatment with a target drug and gene expression is determined (e.g., by microarray analysis, next generation sequencing, or NanoString). After normalization, genes with, e.g., a Pearson correlation greater than 0.25 or below —0.25 can be classified as biomarkers of sensitivity or resistance, respectively.

Biomarkers of responsiveness identified as described above can be used to predict drug responsiveness in subjects, e.g., patients suffering from or susceptible to a disease, disorder, or condition (e.g., colon cancer) treatable with the drug, by measuring their expression level in a biological sample obtained from the subject. For example, the expression level of one or more biomarkers of 5-FU resistance, such as those shown in Table 2 (e.g., NT5E), or biomarkers of 5-FU sensitivity, such as those shown in Table 1, can be measured in a biological sample obtained from the subject, and the resultant measurement can be used to assess the subject's responsiveness to 5-FU treatment. The expression level of a biomarker can be measured in a biological sample, e.g., using a device or method of the present invention. For example, a microarray containing probes directed to one or more such biomarkers can be used to measure the mRNA expression level of the biomarkers. Each probe can have, e.g., at least 5, 10, 15, 20, or 25 or more contiguous nucleic acid residues (e.g., at least 10) that are complementary to a nucleic acid sequence of a selected biomarker; the probe sequence can be at least 85% (e.g., 90%, 95%, 99%, or 100%) identical to the sequence of the biomarker. In some embodiments, subjects showing elevated expression of a biomarker, e.g., relative to the population median, are predicted to be resistant to treatment with the drug, while subjects showing reduced expression of a biomarker, e.g., relative to the population median, are predicted to be sensitive to treatment with the drug. In one embodiment, subjects with an elevated level of NT5E expression relative to the population median are predicted to be resistant to treatment with 5-FU, while subjects with an NT5E expression level below the population median are predicted to be sensitive to 5-FU treatment. In some embodiments, subjects showing elevated expression of a biomarker, e.g., relative to the population median, are predicted to be sensitive to treatment with the drug, while subjects showing reduced expression of a biomarker, e.g., relative to the population median, are predicted to be resistant to treatment with the drug.

The expression level of multiple biomarkers (e.g., biomarkers of sensitivity and/or resistance to a target drug) in a biological sample (e.g., a biological sample obtained from a subject) can be compared to: (i) each other, (ii) a predetermined cutoff level (for example, the expression level in a control, a median expression level observed in a population of controls, or the median expression level in the overall population), or (iii) an expression level in patients that are sensitive and/or resistant to a target drug (e.g., 5-FU, irinotecan, and oxaliplatin). Such comparisons can be used to determine a subject's responsiveness to a target drug, such as 5-FU, irinotecan, and oxaliplatin. For example, the difference in expression level between a biomarker of sensitivity and a biomarker of resistance can be used to predict responsiveness (e.g., sensitivity or resistance) to the target drug.

In some embodiments, a minimum difference in expression level between a biomarker of sensitivity and a biomarker of resistance in the subject is required to classify a subject as responsive (e.g., sensitive and/or resistant) to a target drug. In alternate embodiments, a minimum difference in expression level of a biomarker of sensitivity and/or a biomarker of resistance between a subject and a control (e.g., a population median) is required to classify the subject as responsive (e.g., sensitive and/or resistant) to a target drug. In certain embodiments, the minimum difference is a statistically significant difference (e.g., as determined according to statistical methods well known in the art, such as a t-test). In various embodiments, the minimum difference is at least about 1%, 5%, 10%, 15%, 20%, 25%, 30%, 35%, 40%, 50%, 60%, 70%, 80%, 90%, or 100%.

In other embodiments, a maximum difference in expression level of a biomarker of sensitivity and/or a biomarker of resistance between a subject and the median expression level of the biomarker in a population that is sensitive or resistant, respectively, to the target drug, is required to classify the subject as sensitive or resistant, respectively, to the target drug. In certain embodiments, the maximum difference is a statistically significant difference (e.g., as determined according to statistical methods well known in the art, such as a t-test). In various embodiments, the maximum difference is at least about 1%, 5%, 10%, 15%, 20%, 25%, 30%, 35%, 40%, 50%, 60%, 70%, 80%, 90%, or 100%.

The following tables list biomarkers of responsiveness (sensitivity or resistance) to 5-FU, irinotecan, and oxaliplatin. Each AffyID probeset can match several genes or isoforms, and one gene can be matched by several probesets. Sequences for Almac probes to one or more of the biomarkers of sensitivity or resistance to 5-FU, irinotecan, or oxaliplatin, can also be found in the sequences listed in Tables 7-12, which list probesets, including Almac IDs and probe sequences, which can be used to detect the listed biomarkers.

5-FU

Biomarkers identified as indicative of sensitivity or resistance to 5-FU are shown in Tables 1 and 2, respectively, below.

TABLE 1 Genes predicting sensitivity to 5-FU ranked in order of correlation coefficient (CC). Affymetrix IDs listed are publically available online at the Affymetrix NetAffx ™ Analysis Center. The probe sequence shows the sequence of one (median) of 11 probes listed by Affymetrix for that Affymetrix ID. Gene Affymetrix ID CC Affymetrix Probe sequence SEQ ID NO. APRT 203219_s_at 0.442 CTCTCCTGCAGTATGAGTGACCACA SEQ ID NO. 1 GSR 205770_at 0.408 GCAATAGCTGCTGGCCGAAAACTTG SEQ ID NO. 2 TUFM 201113_at 0.407 GAACATGGCCTGTCGGATTATCCTG SEQ ID NO. 3 MRPS2 218001_at 0.402 GTTACTTACTCAGCTGATGTCACAG SEQ ID NO. 4 MTHFD2 201761_at 0.386 GCTGTCCTTTTGAGGCTTAGTCAGT SEQ ID NO. 5 WDR59 218505_at 0.378 AAGTGCCGGTGACAAGCTGTCTGTC SEQ ID NO. 6 ANP32B 201305_x_at 0.374 GACTGCTCATGGATTTTGTAGCTGT SEQ ID NO. 7 PMM2 203201_at 0.366 AGGAAACGGTTCATGTGTCACTTTT SEQ ID NO. 8 STOML2 215416_s_at 0.366 GGACCCGAGAGTCGGCCATCAATGT SEQ ID NO. 9 NDUFAB1 202077_at 0.364 GAATAAAGTATCAGACCCTTTGGCT SEQ ID NO. 10 ANP32A 201051_at 0.361 TTTGGAGTTCTCTTACGTTTCCTGG SEQ ID NO. 11 IL27RA 222062_at 0.361 GAATGACTGCATGGATAGAACCACT SEQ ID NO. 12 MIR3658 209825_s_at 0.359 GTCAGGAGGCACTGCTCATCTGTAC SEQ ID NO. 13 UCK2 USH1C 211184_s_at 0.358 ACACACACCAGATGGCATCCTTGGG SEQ ID NO. 14 APRT 213892_s_at 0.351 TGCGTGCTCATCCGAAAGCGGGGGA SEQ ID NO. 15 SERPINB1 212268_at 0.347 ACAGCAGGCATCGCAACTTTCTGCA SEQ ID NO. 16 RUVBL1 201614_s_at 0.345 GGACCATGCTGTATACTCCACAGGA SEQ ID NO. 17 HSPD1 200806_s_at 0.341 GAAGCTCTAAGTACACTCGTCTTGA SEQ ID NO. 18 RBM47 218035_s_at 0.338 CTACTGAGGCCTTTAAGCACCGCTA SEQ ID NO. 19 KBTBD11 204301_at 0.336 GTGAGATCAAAGCTCCTCCAAAGCC SEQ ID NO. 20 GCLC 202923_s_at 0.335 TACTCTGGAGCAACCTACTGTCTAA SEQ ID NO. 21 S100A14 218677_at 0.335 CATGTGGGGAGAGGACCAGCTGGGT SEQ ID NO. 22 HMGB1 200679_x_at 0.333 CAAAGGAGAACATCCTGGCCTGTCC SEQ ID NO. 23 MYC 202431_s_at 0.326 GCTAAAACGGAGCTTTTTTGCCCTG SEQ ID NO. 24 HSD17B7 220081_x_at 0.325 TCAGGCCAGGCTCAGTGGCTCATGC SEQ ID NO. 25 FABP5 202345_s_at 0.324 AATGAGCAAATCTCCATACTGTTTC SEQ ID NO. 26 PRIM1 205053_at 0.323 GACAAATATGGACCCTGGCTGGAGT SEQ ID NO. 27 HSPE1 205133_s_at 0.323 GTCGCTGTTGGATCGGGTTCTAAAG SEQ ID NO. 28 MRPS35 217942_at 0.323 TTTCCCCACAAGCTGGCATTTCAGT SEQ ID NO. 29 SLC19A1 211576_s_at 0.32 GCTGGGGAAGTACGTCCCAGCGGCC SEQ ID NO. 30 PGD 201118_at 0.319 TAAGGCAGGCAGCCACCGAGTTTGG SEQ ID NO. 31 LGALS4 204272_at 0.319 CGCTGTGGCTTGGATCGCTTCAAGG SEQ ID NO. 32 PRR13 217794_at 0.319 CCCAGCAGGCCTTTTGTTGGTTGCA SEQ ID NO. 33 EEF1B2 200705_s_at 0.316 GTCTGGGGCTCATCTAAACTAGTTC SEQ ID NO. 34 SNORA41 GTF2E1 205930_at 0.314 GAACTTTCACACAAGGGTCTGTAAC SEQ ID NO. 35 INSIG1 201625_s_at 0.313 GATGACTTACCCTGAAGTCTTCCCT SEQ ID NO. 36 ZFP36 201531_at 0.311 ATATATTGGGTCGTCTGCTTCCCTT SEQ ID NO. 37 SLC9A3R1 201349_at 0.31 GGAAGGTGAATGTGTTCCCGTCCTC SEQ ID NO. 38 PTGES2 218083_at 0.309 GCGCCTGGCGATACTGGTTGGGGGC SEQ ID NO. 39 RNPS1 200060_s_at 0.308 GGTGGTCTTTCAGGTTATCTTGGCA SEQ ID NO. 40 GCNT3 219508_at 0.307 AACCATCACCTGTTGGCCAACAAGT SEQ ID NO. 41 CALML4 221879_at 0.307 CGACCTGCGGTCAAAACTCACGAGT SEQ ID NO. 42 DDC 205311_at 0.306 AATAAATATCATCCTGCCTTCATGG SEQ ID NO. 43 INSIG1 201627_s_at 0.305 AACCAATCTGAGCCTTGTATCTCTT SEQ ID NO. 44 USH1C 205137_x_at 0.305 TGACGATGAGCTGACCTTCTTGCTG SEQ ID NO. 45 GPX2 202831_at 0.304 CAAGACTTGGGTAAGCTCTGGGCCT SEQ ID NO. 46 GCN1L1 216232_s_at 0.304 TAAGAACACCGTGGTCAGGGCCTAC SEQ ID NO. 47 AGMAT 221648_s_at 0.304 GTACCCTCTATGACTGTAATTCCTG SEQ ID NO. 48 TSPAN8 203824_at 0.303 GGTTTGGTGTTTTCTATGGTCCTGT SEQ ID NO. 49 GCSH 213129_s_at 0.303 AATGCCCTTTAACTTTCTAATGATT SEQ ID NO. 50 RPL3 215963_x_at 0.302 GATTGGCCAGGGCTACCTTATCAAG SEQ ID NO. 51 CYBA 203028_s_at 0.3 ACTTTGGTGCCTACTCCATTGTGGC SEQ ID NO. 52 PPRC1 203737_s_at 0.297 GTTCTGCAAGAGGAGCTATTCTGAT SEQ ID NO. 53 HRSP12 203790_s_at 0.297 AAAGCTGCAGGCTGTGACTTCACTA SEQ ID NO. 54 FASN 212218_s_at 0.296 ACACCAGAGCTGCCGACTTGGAGAC SEQ ID NO. 55 CALML4 64408_s_at 0.294 CACCCTTCCTGGACGGGACTATTGA SEQ ID NO. 56 CLDN3 203954_x_at 0.293 AGAAGAAGTACACGGCCACCAAGGT SEQ ID NO. 57 RPL13A 200715_x_at 0.29 TCCTCCATTGTTGCCCTGGAATGTA SEQ ID NO. 58 SNORD32A SNORD33 SNORD34 SNORD35A SEL1L3 212314_at 0.29 GTAGTCTTCTCCATGAATTACACGT SEQ ID NO. 59 MRPL16 217980_s_at 0.289 CTGTGAGCCGCGGGACTCTAGAGAA SEQ ID NO. 60 MUC13 218687_s_at 0.289 GGAGTAAGAGCCTTAGGTCAGTTTG SEQ ID NO. 61 RPL13 212933_x_at 0.288 AAGCACTGTTGGTTGTTTGGTTAGT SEQ ID NO. 62 SNORD68 TPT1 216520_s_at 0.288 GACTCGCTCATTGGTGGAAATGCCT SEQ ID NO. 63 TXN 208864_s_at 0.287 CAGATCGAGAGCAAGACTGCTTTTC SEQ ID NO. 64 TPK1 221218_s_at 0.286 TGGCCCGCGTGATTGTGGCATTTAA SEQ ID NO. 65 TMPO 203432_at 0.285 AGTAATTTTATTTGTTGTCTTCTGA SEQ ID NO. 66 HSP90AB1 214359_s_at 0.284 ATCTCTGTCAGAGTATGTTTCTCGC SEQ ID NO. 67 SHMT2 214437_s_at 0.284 CCTTAACTTCTCGACAGTTCCGTGA SEQ ID NO. 68 SEL1L3 212311_at 0.283 GGAAGGTACGATAATCCCACACCAT SEQ ID NO. 69 ANK3 206385_s_at 0.281 TTACTGTATTGTGTACTGGCTATAA SEQ ID NO. 70 ALG5 218203_at 0.281 GACCTACTTTTTATACGACTTCGAT SEQ ID NO. 71 HMGB1 200680_x_at 0.28 CCTGTCCATTGGTGATGTTGCGAAG SEQ ID NO. 72 CCT3 200910_at 0.28 GGTGAGACGGGTACTTTGGTGGACA SEQ ID NO. 73 TSR3 213105_s_at 0.279 AAAATCTAGAGACATGAGGGACATA SEQ ID NO. 74 ANP32B 201306_s_at 0.275 GTAGCGTGGATAGCTGTGATTGGTG SEQ ID NO. 75 ETS2 201329_s_at 0.273 GGTTCTGGCTGTTTGAGATTCTCAA SEQ ID NO. 76 ATIC 208758_at 0.273 TCAGTCTAACTCTGTGTGCTACGCC SEQ ID NO. 77 RPL13 212191_x_at 0.273 GACCATCGGCATTTCTGTGGATCCG SEQ ID NO. 78 SNORD68 FBXL14 213145_at 0.271 AAAAGGTCACACAGTGCGGCTTCCT SEQ ID NO. 79 LPCAT4 40472_at 0.268 TGGCCAATGGGACTGTGCAAGCACC SEQ ID NO. 80 NUP37 218622_at 0.267 AAGTGTTTTCTGTACCTTAGATTCA SEQ ID NO. 81 WBSCR22 207628_s_at 0.266 GTGTTCACCAATGAGAGGTTCCCAT SEQ ID NO. 82 PDSS1 220865_s_at 0.266 GGTGTGCAACAAACAACCTACCTCG SEQ ID NO. 83 SLX1A- 209607_x_at 0.265 TGAGCGCTTCGATGCGGACTATGCG SEQ ID NO. 84 SULT1A3 SLX1B- SULT1A4 SULT1A3 SULT1A4 GTF3A 215091_s_at 0.265 TATGTCGCTGTCCAAGAGAAGGCTG SEQ ID NO. 85 ATHL1 219359_at 0.265 CAGGTGTGCATGGGTCCAAGGCCCT SEQ ID NO. 86 MIR4680 212593_s_at 0.264 TTTTGTAAGTGCCATGTTTATTATC SEQ ID NO. 87 PDCD4 CNOT1 200860_s_at 0.263 TGCTGTACCTTTTTGCAGAGGCCAA SEQ ID NO. 88 DUSP2 204794_at 0.263 CTCAGCTGACATTTAACACTTCCTC SEQ ID NO. 89 EPCAM 201839_s_at 0.262 ACTTGGACTCCATCGTTAAAATTAT SEQ ID NO. 90 CASP7 207181_s_at 0.261 GAAATGGATGTAAGCCTGGCCCATA SEQ ID NO. 91 RPL13 208929_x_at 0.26 AGCTGACCGGACCGGTCATGCCCGT SEQ ID NO. 92 SNORD68 RPL13 214351_x_at 0.258 TGAAGGAGTACCGCTCCAAACTCAT SEQ ID NO. 93 SNORD68

TABLE 2 Genes predicting resistance to 5-FU ranked in order of correlation coefficient (CC). Affymetrix IDs listed are publically available online at the Affymetrix NetAffx ™ Analysis Center. The probe sequence shows the sequence of one (median) of 11 probes listed by Affymetrix for that Affymetrix ID. Gene Affymetrix ID CC Affymetrix Probe sequence SEQ ID NO. NT5E 203939_at −0.478 GTCACTGTAAATCATTCTTAAGCCC SEQ ID NO. 94 CNN3 201445_at −0.474 GAGCTCAGTATTTAGTCCTTTGTTT SEQ ID NO. 95 ACTN1 208637_x_at −0.44 CTTCCTTCAAGATCCTGGCTGGGGA SEQ ID NO. 96 FLNA 200859_x_at −0.422 GAGGGAGCCATTTGGTGGCGCTGCT SEQ ID NO. 97 ATP2B4 212135_s_at −0.42 CACCTTTCATATCTAGGGACCACCC SEQ ID NO. 98 CYR61 210764_s_at −0.417 TTGTGAGGTGCGGCCTTGTGGACAG SEQ ID NO. 99 ACTN1 208636_at −0.414 AAATCCCCTCAGAGGTGTGACTAGT SEQ ID NO. 100 LGALS1 201105_at −0.411 ATCATGGCTTGTGGTCTGGTCGCCA SEQ ID NO. 101 RHOC 200885_at −0.41 GGCCCCTGGAGTTGTTTCTGCAGGG SEQ ID NO. 102 RAB32 204214_s_at −0.41 GGCTTTGCCGGATGGTTTGAAACCT SEQ ID NO. 103 TMEM158 213338_at −0.409 CACCGATATATTGTTACCGCTGAAA SEQ ID NO. 104 CYR61 201289_at −0.404 GCTTTTATTCGTCCTTTGACAAAAG SEQ ID NO. 105 FLNA 214752_x_at −0.4 AATGGGGGGACGAGCACATCCCAGG SEQ ID NO. 106 SNAPC1 205443_at −0.398 GGTCAAGGGCAAGTCAAAGCAACTA SEQ ID NO. 107 CCND1 208712_at −0.396 CCCGGTCATCTAGCAAGCTGCCGAA SEQ ID NO. 108 FLNA 213746_s_at −0.396 AAAGCAGGCAACAACATGCTGCTGG SEQ ID NO. 109 FYN 210105_s_at −0.384 CCTATGTGATTTTAACTCTGTCTTC SEQ ID NO. 110 TRAM2 202369_s_at −0.376 GCACTCTAGAGCTACTTGTTCACGT SEQ ID NO. 111 DNAJB6 209015_s_at −0.37 GTTGAACTCATGTTTCAGTTCGCGA SEQ ID NO. 112 CD44 212063_at −0.37 TACTTTGACTTTTCAGAGCACACCC SEQ ID NO. 113 PEA15 200787_s_at −0.369 CACCCACCTGTACTCTGGAGAGACT SEQ ID NO. 114 F3 204363_at −0.369 AAAGCTTCTATGGTTGACATTGTAT SEQ ID NO. 115 GRB10 209409_at −0.366 TTCTCTTTTCTGCACTTAATACCTG SEQ ID NO. 116 CD59 200985_s_at −0.363 GGTAGGATATCTTGGCTTTGCCACA SEQ ID NO. 117 PRNP 201300_s_at −0.363 AGGTCTTTGAAATATGCATGTACTT SEQ ID NO. 118 LOC100506032 201103_x_at −0.361 GAGGACAGGTCAGCTGTCTGGCTCA SEQ ID NO. NBPF10 119 NBPF11 NBPF12 NBPF15 NBPF16 NBPF24 NBPF7 NBPF8 NBPF9 VIM 201426_s_at −0.359 GCAGTCCCTCACCTGTGAAGTGGAT SEQ ID NO. 120 CD44 204489_s_at −0.357 TTGAATGGGTCCATTTTGCCCTTCC SEQ ID NO. 121 DKK1 204602_at −0.356 GAGTCTAGAACGCAAGGATCTCTTG SEQ ID NO. 122 MARCKS 201670_s_at −0.353 TGCATACTTTGCATCTTTATTCAAA SEQ ID NO. 123 PPAP2B 212226_s_at −0.352 GCACCATCCCAGTGATGTTCTGGCA SEQ ID NO. 124 IL6ST 212195_at −0.351 GATGGGTCGTGTGATGAGATGCATT SEQ ID NO. 125 CAV1 212097_at −0.35 CAGAAAGCTGCCTGGTATATCCAAA SEQ ID NO. 126 PURA 204020_at −0.346 AGGATTTCCATGTAGCTGTGGTGCT SEQ ID NO. 127 STK17A 202693_s_at −0.345 GTTACTTCATATACTCTAGGACAAT SEQ ID NO. 128 LOX 204298_s_at −0.344 GTTGTGCGCTGTGACATTCGCTACA SEQ ID NO. 129 NR3C1 201865_x_at −0.337 GAACTACGCTTGCTCATTTTTTCTT SEQ ID NO. 130 PPAP2B 212230_at −0.336 GATTATAAACTGTGTCTCGACCTGT SEQ ID NO. 131 MARCKS 201669_s_at −0.333 CGATCATAGTCTTAGGAGTTCATTT SEQ ID NO. 132 LOC100506032 213612_x_at −0.332 TTTACTGTGCCTTTGTTTTTACTAG SEQ ID NO. NBPF10 133 NBPF11 NBPF12 NBPF15 NBPF16 NBPF24 NBPF7 NBPF8 NBPF9 FAM50A 203262_s_at −0.329 GCGCTCGAGATCCTTCGGAAAGACT SEQ ID NO. 134 CAV1 203065_s_at −0.326 ATCTGGGGCATTTACTTCGCCATTC SEQ ID NO. 135 QKI 212636_at −0.322 GTATTTGCAGAGTATTAGCTTTGAA SEQ ID NO. 136 IL6ST 212196_at −0.321 GTACACCTGCCCTAAGGAGAAAATA SEQ ID NO. 137 LEPRE1 220750_s_at −0.321 GAGTCTCTCTCAGGCAGTGAATCGA SEQ ID NO. 138 EMP3 203729_at −0.317 GAGGGGGCAGCTTCGGATACTGCTT SEQ ID NO. 139 GRB10 210999_s_at −0.316 AACGACGATTTGCTGCTGTGAACCC SEQ ID NO. 140 ZNHIT6 218932_at −0.315 TATGTAACTTACCCTTGTGAGACAA SEQ ID NO. 141 CALU 200757_s_at −0.31 GGTATAATGTAACTTCACCCCAGCC SEQ ID NO. 142 PTPRK 203038_at −0.31 ATGCTCCACGTAGCTGTAACTTCAC SEQ ID NO. 143 PSMD2 200830_at −0.309 GGCCACTGAGGAGTTTCTTCCTGTT SEQ ID NO. 144 PCMT1 205202_at −0.309 AACATGCTGTGTAAGCTGTGTCCTA SEQ ID NO. 145 CD59 200983_x_at −0.306 AAAACAGTTCTTCTGCTGGTGACTC SEQ ID NO. 146 THY1 208850_s_at −0.305 CCTCGGCAGGCATGGCTGGTGCCTG SEQ ID NO. 147 CD44 210916_s_at −0.303 GAGTCGTCAGAAACTCCAGACCAGT SEQ ID NO. 148 TRIB2 202478_at −0.302 GTTCGGATTTGACTGCCTGTATATG SEQ ID NO. 149 NR3C1 211671_s_at −0.301 GGACGTAATCTCCACAGTCAAAGAA SEQ ID NO. 150 FTSJ1 205324_s_at −0.3 TGAGTTGTTCACCTTAACCCATTAC SEQ ID NO. 151 CALU 200755_s_at −0.298 GAACCTGCCATTACCTGGGCAAGGA SEQ ID NO. 152 KIF2C 209408_at −0.296 AGGAGCTCTTAGTTACCCTTTTGTG SEQ ID NO. 153 LEPROT 202378_s_at −0.295 GATAACGCTGAAGCAGGCCTCTCAT SEQ ID NO. 154 AAK1 205434_s_at −0.295 CCGCTGCGCGATTGACACGCATATT SEQ ID NO. 155 MAP7D1 217943_s_at −0.295 CCTTGGATCCGGGCACAGTTGTGAG SEQ ID NO. 156 C19orf10 221739_at −0.294 ATCGCAGATCCGGGGCACAAAGAGG SEQ ID NO. 157 CENPF 207828_s_at −0.292 TACCCCTGGGAGGTGCCAGTCATTG SEQ ID NO. 158 CAPN2 208683_at −0.29 AATCGTTCTCCTTACAATCAAGTTC SEQ ID NO. 159 CD44 209835_x_at −0.288 AGCAAACACAACCTCTGGTCCTATA SEQ ID NO. 160 ATM 210858_x_at −0.287 TGCTCATACAGCAGGCCATAGACCC SEQ ID NO. 161 MXRA7 212509_s_at −0.286 GAGCTATCTAGGTTTGTCTGGAAAG SEQ ID NO. 162 THY1 213869_x_at −0.286 CCCTAACGAGACACATTTGCCCAAA SEQ ID NO. 163 FHL2 202949_s_at −0.285 CTCACCCAGGCAATCTTGCCTTCTG SEQ ID NO. 164 RND3 212724_at −0.285 GCAGCCAAGGTCTGTGTTCAGCACT SEQ ID NO. 165 AXL 202686_s_at −0.283 GTTGGACACCTTTAGGTTCTTTGCT SEQ ID NO. 166 LOXL2 202998_s_at −0.281 GACAGGTTGTCATCAGCTTGTCCCA SEQ ID NO. 167 CTNNAL1 202468_s_at −0.28 GATCCATGATGGCTCTCTTAGTCCA SEQ ID NO. 168 CD44 204490_s_at −0.28 GGACACCCCAAATTCCAGAATGGCT SEQ ID NO. 169 TFE3 212457_at −0.28 GCCAGGCCCCATGGAGGGTATACTG SEQ ID NO. 170 SPTAN1 215235_at −0.28 ATCATCATGTCACTGTGGGGACCCA SEQ ID NO. 171 LIMA1 217892_s_at −0.28 AGAACTGTCTTACACCACTTGAGCT SEQ ID NO. 172 MSN 200600_at −0.279 TTATTATTACTGTTTGTCTTCTCCC SEQ ID NO. 173 NR2F2 209121_x_at −0.279 GTTTGTTTGCTTAATTTCCTTCTGT SEQ ID NO. 174 PTPLA 219654_at −0.279 AGAGAGTGTGGTGCTTTTTCTGGTC SEQ ID NO. 175 FHL1 201540_at −0.278 GGATCACCTACTTACTGTATTCTAC SEQ ID NO. 176 C20orf3 206656_s_at −0.278 ATAACGTGCGGTCATACCTTTCTTC SEQ ID NO. 177 OXSR1 202696_at −0.276 GAGATTCCTCCTTATGATGTATGCT SEQ ID NO. 178 TIMP2 203167_at −0.276 GAACCACAGGTACCAGATGGGCTGC SEQ ID NO. 179 OSBPL3 209626_s_at −0.276 ATAACATTAGTGTATTTCTCCTGTG SEQ ID NO. 180 ZNF331 219228_at −0.276 TTCATTTATGGATCGAGCCTCGTGA SEQ ID NO. 181 SEPT7 213151_s_at −0.275 GAAATGGGAATCATGGCCTCTTGAA SEQ ID NO. 182 JUN 201466_s_at −0.274 ATCTATATGGAATTGCTTACCAAAG SEQ ID NO. 183 IFRD1 202146_at −0.274 GCTGTATGAGACTTTGTGCATTTTA SEQ ID NO. 184 CDH11 207173_x_at −0.273 TTTCGCCTTAAACTCTGGACACTCT SEQ ID NO. 185 USP33 214843_s_at −0.273 TGAAGACCTGGTTTTGATGCTGCCT SEQ ID NO. 186 LPP 202822_at −0.272 ACTGATGTAACCTCAAAGCCTCTCA SEQ ID NO. 187 LHFPL2 212658_at −0.27 TTTAAGGGCTAATCTCACACCTCCT SEQ ID NO. 188 PURA 204021_s_at −0.269 GGCGTGTTTATGCGAGTGAGCGAGG SEQ ID NO. 189 FKBP9 212169_at −0.269 TCAACAGAGTATTTCCCTTGGCCGA SEQ ID NO. 190 SOGA2 213358_at −0.269 AATTTGCACTGTTACATTTTGGTTC SEQ ID NO. 191 TUBB 211714_x_at −0.268 CAAGCGCATCTCGGAGCAGTTCACT SEQ ID NO. 192 PTRF 208789_at −0.267 TGATTCTGTTCGGACTGGGTTCTCA SEQ ID NO. 193 PMP22 210139_s_at −0.267 AACTGCTTTTGTACCTAGCTAGGCT SEQ ID NO. 194 RAB31 217762_s_at −0.267 AGGACATTAGGATTGGTGCTCAGAA SEQ ID NO. 195 RAB31 217763_s_at −0.267 GAGTGAGCACACTGGCTTTGCATCC SEQ ID NO. 196 MAP4K4 206571_s_at −0.266 GGAATTCCTTGTAACTGGAGCTCGG SEQ ID NO. 197 CRIM1 202552_s_at −0.264 GGTAATTAATCCATTCCTGGCATAA SEQ ID NO. 198 SVIL 202565_s_at −0.264 GCATTAGGTATGACTTGTTCTGAGT SEQ ID NO. 199 ROBO1 213194_at −0.261 GTTGTGGCCAATGTCGAAACCTACA SEQ ID NO. 200 EMC3 217882_at −0.261 AGACCTCCACTTCGAAGGCATGTTC SEQ ID NO. 201 ULK2 204062_s_at −0.26 GTGGAGTTCCTACATGCAGTGAGTG SEQ ID NO. 202 SCRN1 201462_at −0.259 TCATGTGCACATGCCGTTGCAGCAC SEQ ID NO. 203 RAB31 217764_s_at −0.258 TAAAGAGCTTCCATCTGGGCTGGAC SEQ ID NO. 204 FOXN3 218031_s_at −0.258 ACCGATGTGTCTATGGTGCTGCACC SEQ ID NO. 205 RPF1 218462_at −0.258 AACGGGATTACATATTCTTCAGATT SEQ ID NO. 206 EBNA1BP2 201323_at −0.254 GCCTCAAGAGGCCTGGCAAGAAAGG SEQ ID NO. 207 ATM 212672_at −0.254 AGAATCTGGGGTTTGCCAGTCAGTT SEQ ID NO. 208

In some aspects of the invention, one or more biomarkers of sensitivity and/or resistance to 5-FU are measured in a biological sample obtained from a subject (e.g., a subject suffering from or susceptible to a disease, disorder, or condition treatable with 5-FU, such as cancer, e.g., colon cancer) using, e.g., a microarray, sequencing, NanoString, a protein array, or PCR-based methods, such as those described herein. In certain embodiments, the microarray includes probes capable of recognizing the one or more biomarkers of sensitivity and/or resistance to 5-FU, such as probes at least about 15 nt in length that have, e.g., a sequence with at least 5 (e.g., at least 10) contiguous nucleotides that are complementary to or identical to the sequence(s) of the biomarker(s). In some embodiments of any of the above aspects, any one of the biomarkers from Tables 1 and 2 can be used to assess a subject's sensitivity and/or resistance to treatment with 5-FU. Alternatively, a combination of any of the biomarkers of Tables 1 and 2 may be used. For example, combinations that include the top 5, 10, 15, or 20 biomarkers from Tables 1 and/or 2 may be used. In some embodiments, one or more biomarkers of resistance to 5-FU is selected from the group consisting of NT5E, CNN3, ACTN1, FLNA, ATP2B4, CYR61, LGALS1, RHOC, RAB32, and TMEM158, and/or one or more biomarkers of sensitivity to 5-FU is selected from the group consisting of APRT, GSR, TUFM, MRPS2, MTHFD2, WDR59, ANP32B, PMM2, STOML2, and NDUFAB1. In certain embodiments, the one or more biomarkers of resistance to 5-FU include NT5E, CNN3, ACTN1, FLNA, and/or ATP2B4, and/or the biomarkers of sensitivity to 5-FU include GSR, TUFM, MRPS2, and/or MTHFD2. In particular embodiments, one or more biomarkers of resistance includes NT5E.

Furthermore, a combination of any of the biomarkers of Tables 1-4 can be used to assess a subject's sensitivity and/or resistance to treatment with the combination of 5-FU and irinotecan, and a combination of any of the biomarkers of Tables 1, 2, 5, and 6 can be used to assess a subject's sensitivity and/or resistance to treatment with the combination of 5-FU and oxaliplatin.

Irinotecan

Biomarkers identified as indicative of sensitivity or resistance to irinotecan are shown in Tables 3 and 4, below.

TABLE 3 Genes predicting sensitivity to irinotecan ranked in order of correlation coefficient (CC). Affymetrix IDs listed are publically available online at the Affymetrix NetAffx ™ Analysis Center. The probe sequence shows the sequence of one (median) of 11 probes listed by Affymetrix for that Affymetrix ID. Gene Affymetrix ID CC Affymetrix Probe sequence SEQ ID NO. PRF1 214617_at 0.552 GAGGTGGCTGGGTTTACACGCTAAT SEQ ID NO. 209 GZMB 210164_at 0.527 TGCGAATCTGACTTACGCCATTATT SEQ ID NO. 210 PTPRC 207238_s_at 0.479 GAAGGTTCTGAACCCACGAGTGGCA SEQ ID NO. 211 PTPRC 212587_s_at 0.464 TGGCTGAATTTCAGAGCATCCCGCG SEQ ID NO. 212 PTPRCAP 204960_at 0.462 AGCAATGTGGAGAGGCGTCCAGCCC SEQ ID NO. 213 LOC728802 213388_at 0.46 CCTCTTTCTCAATCTATAACCTTTG SEQ ID NO. PDE4DIP 214 ACAP1 205213_at 0.459 CCCTGCTACGACTGGCAAAGATGAG SEQ ID NO. 215 PTPRC 212588_at 0.459 ATTGCATATGCATAGTTCCCATGTT SEQ ID NO. 216 S1PR1 204642_at 0.456 ACTTTTAAGTCCAGCTATTCATTAG SEQ ID NO. 217 DOCK2 213160_at 0.42 GATTCCTGAACTCAAGGTACCAGCA SEQ ID NO. 218 ARHGEF6 209539_at 0.416 TAACCATGCTTACACACTAAACTAT SEQ ID NO. 219 CD3D 213539_at 0.415 GGAATGACCAGGTCTATCAGCCCCT SEQ ID NO. 220 CYTIP 209606_at 0.414 GTTGTGTTATAGTTTATGCTTCTTA SEQ ID NO. 221 ATF3 202672_s_at 0.412 CTCTCCACTCAATGTCTTAGGTCAG SEQ ID NO. 222 SERPINA1 202833_s_at 0.412 GCATGTTTAACATCCAGCACTGTAA SEQ ID NO. 223 FAM129A 217967_s_at 0.408 GGTAATCTTCTATGTCAGAGCTAGT SEQ ID NO. 224 HSD17B7 220081_x_at 0.408 TGCATACCTTCTGTACATTCTGGGG SEQ ID NO. 225 HCLS1 202957_at 0.405 GAACATTTCTCTTGTGTTCCTGACT SEQ ID NO. 226 CD247 210031_at 0.4 TGATTCACTTCACGCTTTCAGCGAA SEQ ID NO. 227 KBTBD11 204301_at 0.396 AGTGGCCACATCATTTCCACGTTTT SEQ ID NO. 228 LOC728802 214129_at 0.395 GAAAGATCCTTGTCTGATTTTGGCA SEQ ID NO. PDE4DIP 229 FAM129A 217966_s_at 0.393 TACTCATCCTGCTATCAATTTCTTA SEQ ID NO. 230 PHF11 221816_s_at 0.393 ATCACTCTTTGCACACTCTTGTGTT SEQ ID NO. 231 PNMA2 209598_at 0.389 GGATTTTCACGATGTTCCTGTCTGC SEQ ID NO. 232 DDX23 201440_at 0.387 CCAAGGGGTGCTGTATGCTCTAGGC SEQ ID NO. 233 TRIM14 203148_s_at 0.387 AGGGTTACTGATCACTTACCTTCTT SEQ ID NO. 234 CD53 203416_at 0.385 TCTAAATAATGCCCAGTCTTCTCCC SEQ ID NO. 235 ITGA4 213416_at 0.382 GTACTATGGTTGTCCAACACAGGCC SEQ ID NO. 236 NFIL3 203574_at 0.378 GATAGTCCATGCGAAGGCTGTATAT SEQ ID NO. 237 ZAP70 214032_at 0.377 ATCACCAGAATAAACCCAGCTTCCC SEQ ID NO. 238 IL6R 205945_at 0.376 AATATCCAATATTCGCTGTGTCAGC SEQ ID NO. 239 IFI16 208965_s_at 0.373 GGTTAAGTCCTTACTGAGCAACGAT SEQ ID NO. 240 PTPRE 221840_at 0.371 GACACCTGTGTTTCAGCATTTGGAG SEQ ID NO. 241 RAC2 213603_s_at 0.369 GCCAGTCAGGACTTTTGCTATTGCA SEQ ID NO. 242 PSMB9 204279_at 0.368 GTGGACCATCGAGTCATCTTGGGCA SEQ ID NO. 243 PSMD11 208776_at 0.368 GCTGTCCAATATGTAGCCGCTAGCC SEQ ID NO. 244 CCDC109B 218802_at 0.367 AGGATTATACTTACTCAGCTGTTAA SEQ ID NO. 245 GOS2 213524_s_at 0.366 GCCTGACTCCGCTGGGAGAGTGCAG SEQ ID NO. 246 RFTN1 212646_at 0.365 GCTGATTGTCTTGACCAAACCCACA SEQ ID NO. 247 PTPN7 204852_s_at 0.362 GACAGCTGCCTTGATACCAGCTCTC SEQ ID NO. 248 SERPINA1 211429_s_at 0.362 ACCTATGATCTGAAGAGCGTCCTGG SEQ ID NO. 249 ADD2 205268_s_at 0.358 TAAATGCCAACACTGTCTTCTCATG SEQ ID NO. 250 KIAA0226L 44790_s_at 0.357 TTCACTGATGCTGAGCCAGTTTGTA SEQ ID NO. 251 PSMB8 209040_s_at 0.356 GTCATGGACAGTGGCTATCGGCCTA SEQ ID NO. 252 CD93 202878_s_at 0.355 TCAGCAGATTTTGCCCACTATTCCT SEQ ID NO. 253 N4BP2L1 213375_s_at 0.353 ACATGTGTAATTAGTCGGCAGCTCA SEQ ID NO. 254 TPK1 221218_s_at 0.353 TCTGTGTGCCCTGAAAATGTTACCA SEQ ID NO. 255 SELPLG 209879_at 0.348 TCCATCTAGTGACAAGTGACCCCCA SEQ ID NO. 256 WDR59 218505_at 0.348 GCTGATGGACAGTGGCCTTCTAAAA SEQ ID NO. 257 NARF 219862_s_at 0.348 CGGAGAGGTGGTGTTACGCTTTGCT SEQ ID NO. 258 PPRC1 203737_s_at 0.347 GACACATTGTTGAAACAGGCCCAGA SEQ ID NO. 259 HNRNPA1 222040_at 0.346 ATTCCCAGTAGTGACAGTGGATATA SEQ ID NO. 260 SEC31B 209889_at 0.345 GCCTCTGACTTGGTATTTCCAGGTC SEQ ID NO. 261 IKZF1 205038_at 0.344 CCCATATCCCTTCTGTAATTTGTAC SEQ ID NO. 262 IL27RA 222062_at 0.341 CATATGCCAACACGGGGTCTGGGTG SEQ ID NO. 263 STAT3 208991_at 0.339 ACATACTCCTGGCATTGCACTTTTT SEQ ID NO. 264 BATF 205965_at 0.337 ATGCTCAAGTCCCATGGCACAGAGC SEQ ID NO. 265 ARHGAP15 218870_at 0.337 GCCTTTCAAGCGACAGATGCCTCAT SEQ ID NO. 266 SLA 203761_at 0.336 TAAGCATTCCGTCCATCTAAGCTCA SEQ ID NO. 267 LAT 211005_at 0.33 GTGCGAGTCTGAGTCAGAGATTTGG SEQ ID NO. 268 MIR3658 UCK2 209825_s_at 0.328 TGATGTGATCATCCCTAGAGGTGCA SEQ ID NO. 269 NAP1L1 208752_x_at 0.327 GATGAACCTATTCTGAAGCACTTGA SEQ ID NO. 270 CBFB 202370_s_at 0.326 AGAGCTCCTTGGTTTTTTACTTCTG SEQ ID NO. 271 TM6SF1 219892_at 0.325 AAATATTACTTCATGTTCCTCCTTT SEQ ID NO. 272 FMNL1 204789_at 0.324 TCAAGGAAGGTGGTCCTCAGCTCGG SEQ ID NO. 273 INSIG1 201626_at 0.321 GAACAAAATTTGCACTCTACCAGAT SEQ ID NO. 274 IFI16 208966_x_at 0.32 GAAACTTCACCAGACTTTTTCTTCT SEQ ID NO. 275 PRKCQ 210038_at 0.315 CCATTCTCAGCAGACTCCAGTATTG SEQ ID NO. 276 FSCN1 210933_s_at 0.315 GACTCCACAGGCAAATACTGGACGG SEQ ID NO. LOC100653350 277 TRIM22 213293_s_at 0.315 GACTATATCTAATTCCTCTGATCAC SEQ ID NO. 278 TACC3 218308_at 0.315 GACCAACTTACCACAGATCTGAACT SEQ ID NO. 279 SLC35G2 219569_s_at 0.314 CCTTGGACAAATTCCATCCAGCTTT SEQ ID NO. 280 TAF1A 206613_s_at 0.313 GTGAGAAAGCTTTTGTGGCTGGTTT SEQ ID NO. 281 RHOH 204951_at 0.312 CACAACACTTATGTATGCACCCCAA SEQ ID NO. 282 NAP1L1 212967_x_at 0.311 GGGTTGTACAGGGTGCCAGATAGAT SEQ ID NO. 283 JUNB 201473_at 0.308 CTGCTGGAAACAGACTCGATTCATA SEQ ID NO. 284 PTPN2 213137_s_at 0.308 GTGCTCTACGGAAACGTATTCGAGA SEQ ID NO. 285 MCL1 200797_s_at 0.307 GCTGTACTTTTGATAGCTGTGCCAG SEQ ID NO. 286 GNA15 205349_at 0.307 CAGACCGCTGGAAAACACTGTCACT SEQ ID NO. 287 EIF4A1 214805_at 0.307 CTTTTTCCTGGGTCATGCTGCAACA SEQ ID NO. 288 CXorf57 219355_at 0.306 TATTCTTGCTGTACTCATTGGTAGT SEQ ID NO. 289 SAMSN1 220330_s_at 0.305 TGGACACATTTTATCCTGATCCACA SEQ ID NO. 290 INSIG1 201627_s_at 0.302 AGACCATACCAGACCTAATTTGCAA SEQ ID NO. 291 HNRNPR 208765_s_at 0.302 ACCCTCCAGATTACTACGGCTATGA SEQ ID NO. 292 FAM216A 204521_at 0.301 TGGAGAGAGAGGACTCGGGGTCTTC SEQ ID NO. 293 SRSF7 213649_at 0.298 AGATCTACTAGACCATGGGCCAAAG SEQ ID NO. 294 MFNG 204153_s_at 0.295 GCCTTTCTTGCTGTTAGGGGCTACC SEQ ID NO. 295 GPR183 205419_at 0.295 GCAGGACTTCCCTTATAAAGCAAAA SEQ ID NO. 296 BCAT1 214452_at 0.295 GATTTCTTTGGCTACCTGTGCATAA SEQ ID NO. 297 PLAGL1 209318_x_at 0.293 AATAACTTTATGTGGCACTGCCTAG SEQ ID NO. 298 BIRC3 210538_s_at 0.293 CAGGGACACATTTCTCTGTCTTTTT SEQ ID NO. 299 CUTC 218970_s_at 0.293 ACAGAATTCCACTGTTCTGCTCGGT SEQ ID NO. 300 UBE2L6 201649_at 0.292 GTTTGCAGTTACAGGCCAGTTCTCC SEQ ID NO. 301 SLA 203760_s_at 0.292 GTCTGGGTTTGCAGATGGGTGCCCT SEQ ID NO. 302 CYTH4 219183_s_at 0.292 TCTGTCACCTCATTGGTCCATGAAG SEQ ID NO. 303 FAN1 203678_at 0.291 GAGCCAACATCACGTTTTGTTAGCT SEQ ID NO. 304 ANP32B 201305_x_at 0.29 GACTGCTCATGGATTTTGTAGCTGT SEQ ID NO. 305 GMFG 204220_at 0.288 AGCTGAGGAAATTCCGCTTCCGAAA SEQ ID NO. 306 LOC100288366 213646_x_at 0.288 AAATGTGACCCTCGCCATGGTAAAT SEQ ID NO. TUBA1B 307 — 222315_at 0.288 CTGCACCATTCAAACTAGCCAACCC SEQ ID NO. 308 SLC19A1 211576_s_at 0.287 GGCCTCAGGGTCTAAGGAGCGCTAG SEQ ID NO. 309 PMAIP1 204286_s_at 0.285 AGGCAGCTATTTTACCATCTGGTAT SEQ ID NO. 310 EIF1 212225_at 0.285 TAGGCCTAATTCGTTTTCCTTTGTG SEQ ID NO. 311 TRBC1 211796_s_at 0.284 CCGAGGCCTGGGGTAGAGCAGACTG SEQ ID NO. 312 LARS2 34764_at 0.284 CCCCTGCAGTTCAGCAGTTAACAGA SEQ ID NO. 313 SRRT 222047_s_at 0.282 GTATGGTGCTGGTCGAGGGAACTAT SEQ ID NO. 314 CTCF 202521_at 0.281 GATTCTTGCACATGAACTGTCACAT SEQ ID NO. 315 ITK 211339_s_at 0.281 CATGTGACGTTTTGACTGGCTTGAG SEQ ID NO. 316 AKAP2 202759_s_at 0.28 GCCGTATATAGATCAATGTCCACAT SEQ ID NO. PALM2-AKAP2 317 TAP1 202307_s_at 0.279 TGGTGGAGCAGGCTGACCACATCCT SEQ ID NO. 318 TIAM1 213135_at 0.279 CTCCAGTGCAACACATCCATCTGAA SEQ ID NO. 319 CD99 201028_s_at 0.278 TGGAGAAAATGACGACCCACGACCA SEQ ID NO. 320 CSDA 201161_s_at 0.277 ACTGATAGGCAGTTCTCTGGGGCCC SEQ ID NO. 321 IL4R 203233_at 0.277 CCACCAGATCATGGCCCACGTGGAG SEQ ID NO. 322 C1orf114 206721_at 0.277 AAACAGAGATCCACAACAAGCTTTT SEQ ID NO. 323 SLC16A3 202855_s_at 0.276 TGTTCGTGGTGAGCTACGCCAAGGA SEQ ID NO. 324 USP7 201498_at 0.275 GAGGGCATGCTCACTAGTGGTTAGT SEQ ID NO. 325 PAPD7 202466_at 0.275 GTAGGCCTGTACTAATCTCTACGCA SEQ ID NO. 326 RFX5 202963_at 0.275 TGGCAGCATCTTGTCATACGTGTCA SEQ ID NO. 327 MAP4K1 214219_x_at 0.274 CCAGCAACCTCTACATCCAGGAATG SEQ ID NO. 328 WHSC1 209053_s_at 0.272 GATTCCTCGAAACTGCCATTGTGAT SEQ ID NO. 329 CYFIP2 215785_s_at 0.271 ATGGCCGACCGGATCAGGAAGTATC SEQ ID NO. 330 FHOD1 218530_at 0.271 GGTGTGAAGGTGCTGTATCCCGGAA SEQ ID NO. 331 TGFB1 203085_s_at 0.269 TGGATCCACGAGCCCAAGGGCTACC SEQ ID NO. 332 LARP4B 208954_s_at 0.267 AGTGAGTGTCTTGACATTTTCACCC SEQ ID NO. 333 SP110 209762_x_at 0.267 GAGGCTCACCTTAGAGCTTCTGAGT SEQ ID NO. 334 DPY19L1 212792_at 0.266 GGTAGCAGGTTCCATAGGCGTACAA SEQ ID NO. 335 CSDA 201160_s_at 0.265 GATGCTGGTGCTAAACCTCCAAGTG SEQ ID NO. 336 ANP32E 221505_at 0.265 TAATGCTCTTTGTATGGCAGTATGT SEQ ID NO. 337 FLI1 204236_at 0.264 TGACCTCGGTCACAAAAGCAGTTTT SEQ ID NO. 338 ARHGAP19 212738_at 0.263 GCTAATGCCGAGATCTTCTACCAGC SEQ ID NO. 339 POM121 213360_s_at 0.263 CCTTATGTAAGGTAGACCCTCCTAG SEQ ID NO. POM121C 340 LOC100506390 200833_s_at 0.262 GATTGTGTGTCTATCCAACAGGGAG SEQ ID NO. RAP1B 341 PSMB10 202659_at 0.262 CCACGTGGGTGCATCGCTGATCGTG SEQ ID NO. 342 RHOG 203175_at 0.262 TCCAGCTTTCCACACAGTTGTTGCT SEQ ID NO. 343 FNBP1 212288_at 0.262 GAGTTGCCTGTTTGTCTCTGGAGAT SEQ ID NO. 344 KIAA0226L 219471_at 0.262 CCCGGTGTGCGAGGATCACAGCGAG SEQ ID NO. 345 DNAJC2 213097_s_at 0.261 ATAGCAGAAGCGGTGCCTGGCAGGA SEQ ID NO. 346 ANP32B 201306_s_at 0.259 CTTCCATGTAGTCCCTCTTGGTAAT SEQ ID NO. 347 TRIP13 204033_at 0.259 ATAGGTCAGTTACTGGTCTCTTTCT SEQ ID NO. 348 SP140 207777_s_at 0.259 GGGAAGGATGTTGGCAGCGACACCA SEQ ID NO. 349 PRPF3 202251_at 0.258 GACCTTGCGCTGAGTGAATCTGTGT SEQ ID NO. 350 ICOS 210439_at 0.257 CAGGTGTTCCCTGAGTTGTTTGCAG SEQ ID NO. 351 CORO1A 209083_at 0.256 TATCTCTCCATGTTCAGTTCCAAGG SEQ ID NO. 352 TRBC1 210915_x_at 0.255 AAAGGCCACACTGGTGTGCCTGGCC SEQ ID NO. 353

TABLE 4 Genes predicting resistance to irinotecan ranked in order of correlation coefficient (CC). Affymetrix IDs listed are publically available online at the Affymetrix NetAffx ™ Analysis Center. The probe sequence shows the sequence of one (median) of 11 probes listed by Affymetrix for that Affymetrix ID. Gene Affymetrix ID CC Affymetrix Probe sequence SEQ ID NO. CCND1 208712_at −0.406 ATCTCAATGAAGCCAGCTCACAGTG SEQ ID NO. 354 LGALS3 208949_s_at −0.404 TGATTGTGCCTTATAACCTGCCTTT SEQ ID NO. 355 INPP4B 205376_at −0.38 GAATGGTATTCGTTTCACCTGTTGT SEQ ID NO. 356 TMEM97 212281_s_at −0.344 TACAGCCAGGCATAACATATCCACT SEQ ID NO. 357 TCF7L2 212761_at −0.332 GTTTTATGCTCTTATTCCAAGTTCA SEQ ID NO. 358 SFN 33323_r_at −0.33 GCATGTCTGCTGGGTGTGACCATGT SEQ ID NO. 359 LAPTM4B 214039_s_at −0.327 CCAAGTATGTCTAGTCACCTTTTAA SEQ ID NO. 360 LSR 208190_s_at −0.323 GTCGTCTGATCTGACGTTTTCTACG SEQ ID NO. 361 SFN 209260_at −0.323 CCTGCTGCCTCTGATCGTAGGAATT SEQ ID NO. 362 TMEM97 212282_at −0.317 GTCTAGCATCTCAAGGCTGATCTGG SEQ ID NO. 363 SFN 33322_i_at −0.313 ATGTCTGCTGGGTGTGACCATGTTT SEQ ID NO. 364 C19orf21 212925_at −0.303 TGAAATGGGACCCCTGCTGATTCTT SEQ ID NO. 365 SERPINB6 211474_s_at −0.302 AGGCAGACTTCTCTGGAATGTCCCA SEQ ID NO. 366 NR2F2 209120_at −0.3 AGACACATGCTGAGGTTTTGAATAA SEQ ID NO. 367 CTBP2 210835_s_at −0.299 ATTGAAGACAGTACAGGCTGCTGTA SEQ ID NO. 368 LAPTM4B 208767_s_at −0.298 TCTGTTCCCTCTCTTTTGAAAATGT SEQ ID NO. 369 SQLE 209218_at −0.297 TCTCCTAACCCTCTAGTTTTAATTG SEQ ID NO. 370 SORL1 203509_at −0.292 GAATATCACAGCTTACCTTGGGAAT SEQ ID NO. 371 GPX4 201106_at −0.29 ATCTGCGTGAACGGGGACGACGCCC SEQ ID NO. 372 JUP 201015_s_at −0.286 TCTCTGGGTCTGATTTTCTCACTGA SEQ ID NO. 373 LAPTM4B 208029_s_at −0.286 AAGACCATTAGAAAGCACCAGGCCG SEQ ID NO. 374 ACTN1 208636_at −0.279 ATATTCCATCCTTTTTACTGATTTT SEQ ID NO. 375 CPNE3 202119_s_at −0.277 AAATTACCCATATTGACTTTCACAC SEQ ID NO. 376 TJP1 202011_at −0.274 ATGCGTGCATACCACTTTTGTTCTT SEQ ID NO. 377 KRT18 201596_x_at −0.272 GAGCTGCTGAGACGACGCTCACAGA SEQ ID NO. 378 KDELR3 204017_at −0.271 GATACCTGCCTTGTACTTAGTACCT SEQ ID NO. 379 DSG2 217901_at −0.27 AAGTTGGTCTTAAGCTTCCACCTTG SEQ ID NO. 380 LRP5 209468_at −0.268 GAAAGTCCATGATGAGCTCCGTGAG SEQ ID NO. 381 SUV420H1 218242_s_at −0.268 TCCCTTCACTTATCAGCATACTATT SEQ ID NO. 382 CTBP2 201220_x_at −0.267 ATAGAGCTTTTTCCTTTATCAGTCC SEQ ID NO. 383 RRBP1 201204_s_at −0.266 AGAGCCCCAGTTTGTAAATGAACCT SEQ ID NO. 384 EPCAM 201839_s_at −0.266 ACTTGGACTCCATCGTTAAAATTAT SEQ ID NO. 385 LAD1 203287_at −0.266 GCTGTGGATCTGTTTGGCCAGGGTC SEQ ID NO. 386 PPAP2B 212226_s_at −0.266 GAAATCCTTTCACCTGTGGACATTA SEQ ID NO. 387 SORL1 212560_at −0.266 ATCGTCACAGCCAAGTAATAACCCA SEQ ID NO. 388 LITAF 200704_at −0.265 GACCTTCAAGGGTCCTCGTTTTGAT SEQ ID NO. 389 ACTN1 208637_x_at −0.265 CCCTGCCCGCGAAGTGACAGTTTAC SEQ ID NO. 390 APOBEC3B 206632_s_at −0.263 AGCAATGTGCTCCTGATCAAGTAGA SEQ ID NO. 391 LITAF 200706_s_at −0.262 TTCTCTGTGCCAGATCTTCAGTGCC SEQ ID NO. 392 ASAH1 213702_x_at −0.262 CAAGACCGTTTGTCCACTTCATTTT SEQ ID NO. 393 MLPH 218211_s_at −0.262 TTCACTCTTGGCTTTCTTATGTTGC SEQ ID NO. 394 LAMB1 201505_at −0.261 ATAGCACATGCTTGTAACAGAGGAG SEQ ID NO. 395 TGFBR3 204731_at −0.26 GAATAGTGTCACCAATTCCACCAAG SEQ ID NO. 396 TMEM97 212279_at −0.259 ATACTCTCCACATTTCTGTTTGAGG SEQ ID NO. 397 SLC25A1 210010_s_at −0.256 TCATGTTCTGTGTCACGTGACCCTG SEQ ID NO. 398

In some aspects of the invention, one or more biomarkers of sensitivity and/or resistance to irinotecan are measured in a biological sample obtained from a subject (e.g., a subject suffering from or susceptible to a disease, disorder, or condition treatable with irinotecan, such as cancer, e.g., colon cancer) using, e.g., a microarray, sequencing, NanoString, a protein array, or PCR-based methods, such as those described herein. In certain embodiments, the microarray includes probes capable of recognizing the one or more biomarkers of sensitivity and/or resistance to irinotecan, such as probes at least about 15 nt in length that have, e.g., a sequence with at least 5 (e.g., at least 10) contiguous nucleotides that are complementary to or identical to the sequence(s) of the biomarker(s). In embodiments of any of the above aspects, any one of the biomarkers from Tables 3 and 4 can be used to assess a subject's sensitivity and/or resistance to treatment with irinotecan. Alternatively, a combination of any of the biomarkers of Tables 3 and 4 may be used. For example, combinations that include the top 5, 10, 15, or 20 biomarkers from Tables 3 and/or 4 may be used. In some embodiments, one or more biomarkers of sensitivity to irinotecan is selected from the group consisting of PRF1, GZMB, PTPRC, PTPRC, PTPRCAP, PDE4DIP, ACAP1, PTPRC, S1PR1, and DOCK2, and/or one or more biomarkers of resistance to irinotecan are selected from the group consisting of CCND1, LGALS3, INPP4B, TMEM97, TCF7L2, SFN, LAPTM4B, LSR, SFN, and TMEM97. In certain embodiments, the one or more biomarkers of sensitivity include PRF1, GZMB, PTPRC, PTPRC, and/or PTPRCAP, and the one or more biomarkers of resistance include CCND1, LGALS3, INPP4B, TMEM97, and/or TCF7L2. In particular embodiments, one or more biomarkers of sensitivity include PRF1.

Furthermore, a combination of any of the biomarkers of Tables 1-4 can be used to assess a subject's sensitivity and/or resistance to treatment with the combination of 5-FU and irinotecan, and a combination of any of the biomarkers of Tables 3-6 can be used to assess a subject's sensitivity and/or resistance to treatment with the combination of irinotecan and oxaliplatin.

Oxaliplatin

Biomarkers identified as indicative of sensitivity and resistance to oxaliplatin are shown in Tables 5 and 6, below.

TABLE 5 Genes predicting sensitivity to oxaliplatin ranked in order of correlation coefficient (CC). Affymetrix IDs listed are publically available online at the Affymetrix NetAffx ™ Analysis Center. The probe sequence shows the sequence of one (median) of 11 probes listed by Affymetrix for that Affymetrix ID. Gene Affymetrix ID CC Affymetrix Probe sequence SEQ ID NO. MRPL16 217980_s_at 0.444 ACGTGACACCTGTGAAGGCTGGCCG SEQ ID NO. 399 ANP32A 201051_at 0.432 TCACATGATGATACCTGCTTTTCTC SEQ ID NO. 400 SRSF2 214882_s_at 0.428 AGAGTCCTTGGAACAAGCAACTGGC SEQ ID NO. 401 PDSS1 220865_s_at 0.413 CTGTTCTTTCTGGCAGCTATCTTAC SEQ ID NO. 402 PRIM1 205053_at 0.411 CGCATCTCTGTGCCTATTGATTTGC SEQ ID NO. 403 HNRNPA1 222040_at 0.409 TAGTCATTCACCTCTGCTTATATGA SEQ ID NO. 404 NDUFAB1 202077_at 0.407 GAGGACACATTTTGGCATTCTTGCT SEQ ID NO. 405 GLTSCR2 217807_s_at 0.393 GTTGTAGCTGCCATCAGATGCCGGA SEQ ID NO. 406 RNPS1 200060_s_at 0.389 CCCCGATGACCTGGGATGGTGGCCA SEQ ID NO. 407 ICAM2 213620_s_at 0.388 GTGTCGGACAGCCAGATGGTCATCA SEQ ID NO. 408 DENND2D 221081_s_at 0.388 TTCTCACTTTTCATCCAGGAAGCCG SEQ ID NO. 409 LCP1 208885_at 0.383 GGAGTCCCAAATGTCATCAGGTTTT SEQ ID NO. 410 SEPT6 213666_at 0.383 GAACCAGCACTGTTTAGCCTGATAC SEQ ID NO. 411 NUP210 213947_s_at 0.383 TAAATAGGAGCCTTTCTACTGGTTT SEQ ID NO. 412 CORO1A 209083_at 0.379 GCTCCAGAAGCGCTTGGACAGGCTG SEQ ID NO. 413 SHMT2 214437_s_at 0.379 TGAAGAGCAAGACTGCCAAGCTCCA SEQ ID NO. 414 USP7 201498_at 0.378 GCCTTGGCAGACTTACGATCTCAAC SEQ ID NO. 415 GLYR1 SEPT6 212414_s_at 0.376 AATCATTTGGCATTCACATGTGGCT SEQ ID NO. 416 TUFM 201113_at 0.375 TAGAGAAAGGCCAGCGTTTCACCCT SEQ ID NO. 417 RPL13A 200715_x_at 0.374 TCCTCCATTGTTGCCCTGGAATGTA SEQ ID NO. SNORD32A 418 SNORD33 SNORD34 SNORD35A MYB 204798_at 0.374 GCTGCTATGGTCTTAGCCTGTAGAC SEQ ID NO. 419 ICAM2 204683_at 0.37 TGAGACTCTGCACTATGAGACCTTC SEQ ID NO. 420 CYFIP2 215785_s_at 0.365 CAGCCTGCCATAGGATCCAACTGGA SEQ ID NO. 421 BCL11A 210347_s_at 0.362 GTGGAAATGCGCATGAGTCCCCAAC SEQ ID NO. 422 EZH2 203358_s_at 0.358 TTTTGCCAAGAGAGCCATCCAGACT SEQ ID NO. 423 SEPT6 212415_at 0.358 AGAAAATAGCAGACGTTTCCCCTCT SEQ ID NO. 424 MRPS2 218001_at 0.356 GTGAGCGACATGTGCAGAACGGCCC SEQ ID NO. 425 HCLS1 202957_at 0.355 GGTTTGCCTCATTGTGCTATTTGCC SEQ ID NO. 426 HNRNPA1 214280_x_at 0.355 TGTTCTGCAGCTCAAATTCCATTTT SEQ ID NO. 427 CYFIP2 220999_s_at 0.353 GAGTTGATAAACATTTCCATCTTCA SEQ ID NO. 428 MYC 202431_s_at 0.351 GCAACCTCACAACCTTGGCTGAGTC SEQ ID NO. 429 NCKAP1L 209734_at 0.35 TGCCTATCGGGAGGTGTCTCGGGCC SEQ ID NO. 430 REPIN1 219041_s_at 0.349 GATGGAGGGCCAGCTGAGGGGAAGT SEQ ID NO. 431 MTHFD2 201761_at 0.348 GTATGTTACCCTTCAGTAAGTTCTC SEQ ID NO. 432 EWSR1 209214_s_at 0.345 CAGTGTCCCAATCCGGGTTGTGGAA SEQ ID NO. 433 GCH1 204224_s_at 0.344 TTCATATCCATGATCTTGAGTCCAT SEQ ID NO. 434 SRSF7 213649_at 0.343 CCTAGCTTCACCTTATTCTTTAAAG SEQ ID NO. 435 HNRNPA2B1 205292_s_at 0.341 GAGGATGAGAGCCCAGAGGTAACAG SEQ ID NO. 436 MZB1 221286_s_at 0.341 AAGACCAGATCTATGAAGCCCACCA SEQ ID NO. 437 ALDH5A1 203608_at 0.339 GAGCTGATCTGCATCTGTTTATCCA SEQ ID NO. 438 PPRC1 203737_s_at 0.339 TGAAACAGAGGTTCTCCGTTTTTGG SEQ ID NO. 439 PCCB 212694_s_at 0.339 AGCTTCTCTACGCATTTGCTGAGGC SEQ ID NO. 440 PSMB10 202659_at 0.338 CTCACCCACAGAGCCCGTGAAGAGG SEQ ID NO. 441 ATHL1 219359_at 0.338 GCCTCTGCTACAGCGTGGAGTGGGA SEQ ID NO. 442 SLC9A3R1 201349_at 0.336 GGAAGGTGAATGTGTTCCCGTCCTC SEQ ID NO. 443 RHOH 204951_at 0.335 TGTTTTCTCTGGGTACACCCCAAGC SEQ ID NO. 444 SKAP1 205790_at 0.335 GGGCCTATGGGATTGCCATGGTGAC SEQ ID NO. 445 GTF3A 215091_s_at 0.334 TACAACTGTGTTTAATCTCCAAAGC SEQ ID NO. 446 MIR1292 200875_s_at 0.333 TCCAAAGAGGAGCCGGTCAGCAGTG SEQ ID NO. NOP56 447 SNORD110 SNORD57 SNORD86 MFNG 204153_s_at 0.331 ATCTTCCTGCTATAAATGTGGGTGT SEQ ID NO. 448 SHMT2 214096_s_at 0.331 GTGCCCTTCAGAGCCAGTAGCAGGC SEQ ID NO. 449 PRKX PRKY 204060_s_at 0.33 CTTAGTTTGATCTTCCATGGTGGAC SEQ ID NO. 450 CNBP 206158_s_at 0.33 GTCTGACCTCAGTAGCTATTAAATA SEQ ID NO. 451 CD8B 207979_s_at 0.33 GAGTAAGAAATGCTGCCCATGCCAC SEQ ID NO. 452 RPS3A 200099_s_at 0.328 GACCCGAGAGGTGCAGACAAATGAC SEQ ID NO. SNORD73A 453 PAICS 201014_s_at 0.328 GAACACTGCATATCCAGTTATCAGC SEQ ID NO. 454 CXCR4 209201_x_at 0.327 GTTGGCTGCCTTACTACATTGGGAT SEQ ID NO. 455 AKAP1 201675_at 0.324 GTAACCATTTTCTATTTGTGCAAAC SEQ ID NO. 456 LOC100506248 211921_x_at 0.324 GAGGATGACGATGTCGATACCAAGA SEQ ID NO. LOC728026 457 MIR1244-1 MIR1244-2 MIR1244-3 PTMA FABP5 202345_s_at 0.321 GCATTGGTTCAGCATCAGGAGTGGG SEQ ID NO. 458 RNF44 203286_at 0.319 CTAGGCATGACAGTGGGCACCTTCC SEQ ID NO. 459 RNU86 RPL3 211666_x_at 0.318 GCCTGCGCAAGGTGGCCTGTATTGG SEQ ID NO. SNORD83B 460 CXCR4 217028_at 0.318 GTTTTTCCTGTTCTTAAGACGTGAT SEQ ID NO. 461 GTF3A 201338_x_at 0.317 TTGGCCTCTCATCTCAGTGGATATA SEQ ID NO. 462 GMFG 204220_at 0.317 AAGACCGGCAGATGGTGGTGCTGGA SEQ ID NO. 463 WDR59 218505_at 0.317 GGGCCAGTGTTACAGTGTTACCCTG SEQ ID NO. 464 NASP 201970_s_at 0.316 GAGAGTCCCCGGAAAGATGATGCAA SEQ ID NO. 465 TRIM14 203148_s_at 0.313 CATGCCAGGATTTATCAGCATTCCC SEQ ID NO. 466 CALML4 221879_at 0.311 AGAAATTCTTCTAGCCATGTTGATG SEQ ID NO. 467 HNRNPM 200072_s_at 0.309 GCCGAGAGAGCCTGCCGGATGATGA SEQ ID NO. 468 HMGB1 200679_x_at 0.309 GAGAGGTGGAAGACCATGTCTGCTA SEQ ID NO. 469 TTF1 204771_s_at 0.309 ATTACAGAACTACCAGCATCTGCTC SEQ ID NO. 470 TSR3 213105_s_at 0.309 ACATAAATGGGCCTGGCAGCCTCGG SEQ ID NO. 471 ADA 204639_at 0.307 TGGTTGAATCTGAAACCCTCCTTCT SEQ ID NO. 472 GCN1L1 216232_s_at 0.307 AACCTCCTCAAGATGCGGCAGGGTG SEQ ID NO. 473 PTMA 208549_x_at 0.306 ACGCCCCTGCTGACGAGGAAAATGG SEQ ID NO. 474 DAZAP1 218443_s_at 0.306 GAGCCTTTTGTTTTACGGTATATTG SEQ ID NO. 475 THUMPD1 206555_s_at 0.305 GTTCAGAAATCACCTTTAGTCAAAA SEQ ID NO. 476 MDN1 212693_at 0.305 GTGCTCTGTTCTACTTAATGTTCTG SEQ ID NO. 477 CD53 203416_at 0.301 GCATCTTCCCATTGTCGAATTAGTC SEQ ID NO. 478 RPL13 212933_x_at 0.301 AATTTCAAAGCCTTCGCTAGTCTCC SEQ ID NO. SNORD68 479 ADA 216705_s_at 0.301 ATCAATGCGGCCAAATCTAGTTTCC SEQ ID NO. 480 CD247 210031_at 0.3 AAATTTGGCTTCTGTTGTCACCTTC SEQ ID NO. 481 FBXL14 213145_at 0.3 GTAGGATGTATATTTTCGTTGGATT SEQ ID NO. 482 TMEM177 218897_at 0.3 CGAATCAAACATTTACCCTACACCA SEQ ID NO. 483 PCBP2 204031_s_at 0.298 GATGCATCTGCTCAGACTACTTCTC SEQ ID NO. 484 UTP3 209486_at 0.297 GATCAACAAGCTGTCCGTTGTGGAT SEQ ID NO. 485 RUVBL1 201614_s_at 0.296 GTAACTGTTCCTGTGGTTGCTTTGA SEQ ID NO. 486 LGALS9 203236_s_at 0.296 ATGTGCAGACATAGGCGGCTTCCTG SEQ ID NO. 487 CXCR4 211919_s_at 0.296 GTGGTCTATGTTGGCGTCTGGATCC SEQ ID NO. 488 CD3D 213539_at 0.296 GAAGCAGCCATTACCAACTGTACCT SEQ ID NO. 489 AQP3 39248_at 0.296 CTGTCATAATGCAGGCATGAAGGGT SEQ ID NO. 490 CBFA2T3 208056_s_at 0.294 GAAATTCATGCTTGCACCGAGTACA SEQ ID NO. 491 SH2D1A 211210_x_at 0.294 GCTTGCCACTGGGCTGGATGGCAGC SEQ ID NO. 492 HSPD1 200807_s_at 0.292 GAAGTTAAGCAGCCTTTCTGTGGAG SEQ ID NO. 493 NAP1L1 212967_x_at 0.292 ATCCTTGCTGCAGACTTCGAAATTG SEQ ID NO. 494 PTPN2 213137_s_at 0.292 GTGCTCTACGGAAACGTATTCGAGA SEQ ID NO. 495 CDK5RAP3 218740_s_at 0.292 GCAACACCTGTTTATGATCCTGGCC SEQ ID NO. 496 CHD7 218829_s_at 0.292 GCATTACCTCAGCTCTAAACTAGCC SEQ ID NO. 497 EEF1B2 200705_s_at 0.291 GTCTGGGGCTCATCTAAACTAGTTC SEQ ID NO. SNORA41 498 ITGB7 205718_at 0.291 GACAGTCCCACTCTCTGAAGGAGGG SEQ ID NO. 499 BIN2 219191_s_at 0.291 TCTTTGACTTACGACCCATTTTGCA SEQ ID NO. 500 BLM 205733_at 0.29 GAGGAAATACCCGTATCTTCCCACT SEQ ID NO. 501 SHMT2 214095_at 0.29 CAAACAGTGATTTGTCTCCCTCAAT SEQ ID NO. 502 RPS6 209134_s_at 0.289 TCCTGGACTGACTGATACTACAGTG SEQ ID NO. 503 TRBC1 210915_x_at 0.288 TGACTCCAGATACTGCCTGAGCAGC SEQ ID NO. 504 LOC100506248 200772_x_at 0.286 CACCATGTCAGACGCAGCCGTAGAC SEQ ID NO. LOC728026 505 MIR1244-1 MIR1244-2 MIR1244-3 PTMA ATP5G2 208764_s_at 0.284 CTCTTTTGTCTGATGGTAGCCTTTC SEQ ID NO. 506 TOP1 208901_s_at 0.284 GCATTCGCTGTACCCTTTAAGATAT SEQ ID NO. 507 MX2 204994_at 0.283 TACTCCCTCAGCATCAGAGCATGCA SEQ ID NO. 508 MAP4K1 206296_x_at 0.283 TACAGGAGCTGAGAGACCCTACCCT SEQ ID NO. 509 SH2D1A 211211_x_at 0.283 AGAGAAGATCCTGATGTCTGCCTGA SEQ ID NO. 510 HSPD1 200806_s_at 0.282 TAGTATCCAGTCCATTGTACCTGCT SEQ ID NO. 511 ITM2A 202747_s_at 0.282 GAGCTCTTTGGCAAACTGGCGAGTG SEQ ID NO. 512 ATIC 208758_at 0.282 TGTGATTGAGGCCTGCGACGAACTG SEQ ID NO. 513 RPL10A 200036_s_at 0.281 GACCAGCAGCACTGTGACGAGGCTA SEQ ID NO. 514 UBE2L6 201649_at 0.28 GTTTGCAGTTACAGGCCAGTTCTCC SEQ ID NO. 515 RAD51C 209849_s_at 0.28 GCTGCTACAATACGGCTAATCTTTC SEQ ID NO. 516 ABCA7 219577_s_at 0.28 GGAAGGACGAGGACACCGAAGAGCA SEQ ID NO. 517 TMEM176B 220532_s_at 0.28 GGGTACAGATGGATGCGGCGAAGTC SEQ ID NO. 518 MSH2 209421_at 0.279 AGCCCTGGAACTTGAGGAGTTTCAG SEQ ID NO. 519 ATP2A3 213036_x_at 0.279 AATGGGCTCCATGTTCTGTAGCCCC SEQ ID NO. 520 IFITM1 214022_s_at 0.278 TTCTTGAACTGGTGCTGTCTGGGCT SEQ ID NO. 521 SNRNP70 201221_s_at 0.277 CCATCTGCTGTGTTTGGACGCGTTC SEQ ID NO. 522 IMPDH2 201892_s_at 0.277 TCATATTGCGAAAGCCTTGGCCCTT SEQ ID NO. 523 SNRPG 205644_s_at 0.277 GATGGCGACTAGTGGACAACAGAAC SEQ ID NO. 524 MAP4K1 214219_x_at 0.277 TCCCCCAGGCCTGTAGTGGTGGAGA SEQ ID NO. 525 TRA2B 200892_s_at 0.276 TACTCACCTCGTCGCTATTAAAGCA SEQ ID NO. 526 RPL3 215963_x_at 0.276 TGGTGCAGATGAAACGGCAGGCTCT SEQ ID NO. 527 TRIAP1 218403_at 0.276 GTGAACACCATTTCAGAGCTCTCAG SEQ ID NO. 528 ARHGAP15 218870_at 0.275 ACGTTCACATCTGTCTTGATGCCTA SEQ ID NO. 529 PTPN2 213136_at 0.274 GATTACTTTGTATTGTACTGCCATT SEQ ID NO. 530 — 216380_x_at 0.274 CAGCCACGTGCAGCCTATCAAGCTG SEQ ID NO. 531 TPT1 216520_s_at 0.274 GATATTGTCATGAACCATCACCTGC SEQ ID NO. 532 PVRIG 219812_at 0.274 AGGACCCTTAGGAGTTCGATGAGAG SEQ ID NO. 533 SRSF5 203380_x_at 0.273 TAAACTGTAAATAACTTGCCCTGGG SEQ ID NO. 534 IQGAP2 203474_at 0.273 ACTGTGATATAGGTACTCTGATTTA SEQ ID NO. 535 PIM2 204269_at 0.273 TATCCCAAGTGCTCTTATTCTGGTG SEQ ID NO. 536 CALML4 64408_s_at 0.273 CTTCTAGCCATGTTGATGGTGGACA SEQ ID NO. 537 IL2RG 204116_at 0.272 GGTGTGTCTAAGGGACTGGCTGAGA SEQ ID NO. 538 PTPN7 204852_s_at 0.272 ACCTCAGGTCTACCTCAGGACTGAA SEQ ID NO. 539 ATP2A3 207522_s_at 0.272 AGGAAGATGGCCTCTGATGGACAGA SEQ ID NO. 540 NFATC3 210555_s_at 0.272 GAGCCTAACTTTGCAACCATTGGTC SEQ ID NO. 541 CD3G 206804_at 0.269 TGGAGTTCGCCAGTCGAGAGCTTCA SEQ ID NO. 542 CD1C 205987_at 0.268 AATATAGTGATGCCATCCCGTCGAC SEQ ID NO. 543 SLC19A1 211576_s_at 0.268 GTGGGCGCTGGGGAAGTACGTCCCA SEQ ID NO. 544 IRF7 208436_s_at 0.267 CAACAGCCTCTATGACGACATCGAG SEQ ID NO. 545 FYB 211795_s_at 0.267 ATGTCCTTCGGAGTTACCTAGCGGA SEQ ID NO. 546 ITM2A 202746_at 0.266 CATCCTGACAATAAATTCCATCCGT SEQ ID NO. 547 TRBC1 211796_s_at 0.266 TCGGAGAATGACGAGTGGACCCAGG SEQ ID NO. 548 BCL11B 219528_s_at 0.266 TAAGGAAATCAGCCTTTCATCCCGG SEQ ID NO. 549 HMGB1 200680_x_at 0.265 GTCTATAAAGCATTTAACCCCCCTG SEQ ID NO. 550 RPL27A 203034_s_at 0.265 TACCACTTAAAGAGGAACCAGAGCT SEQ ID NO. SNORA3 551 PFDN5 210908_s_at 0.265 GCGCAGTCTATTAACATCACGGAGC SEQ ID NO. 552 IKZF1 205038_at 0.264 CCCATATCCCTTCTGTAATTTGTAC SEQ ID NO. 553 CD28 206545_at 0.264 AACAATGTCATTTGCTGCTATTATT SEQ ID NO. 554 RNU86 RPL3 212039_x_at 0.264 GATCAAGAACAATGCCTCCACTGAC SEQ ID NO. SNORD83B 555 SRSF3 208672_s_at 0.263 GAAACACAGGCCATCAGGGAAAACG SEQ ID NO. 556 ANP32B 201305_x_at 0.262 AAGACCCCAGATGACCTGCAGAAAC SEQ ID NO. 557 P2RX5 210448_s_at 0.262 GGGAATAGCATTGTGCGTGTCCGGA SEQ ID NO. 558 TMPO 203432_at 0.261 ATCTCTTCATTGACTGGTAGCAACC SEQ ID NO. 559 LCP2 205269_at 0.261 AAAAGATTATTTAATGCCCATTTCA SEQ ID NO. 560 HNRPDL 209067_s_at 0.261 CAATAGTGCCTATGGTGGTGATCAA SEQ ID NO. 561 TFB1M 219169_s_at 0.261 TCACTCCCTTGATACAGCCCAAGAT SEQ ID NO. 562 RNU86 RPL3 211073_x_at 0.26 TACCATCACCGCACTGAGATCAACA SEQ ID NO. SNORD83B 563 TRAF3IP3 213888_s_at 0.26 GAGGCAGCGGGATGGACTACATGAC SEQ ID NO. 564 LRMP 204674_at 0.259 TCCAGAAGTCTGTGGATGCCGCTCC SEQ ID NO. 565 SRSF5 212266_s_at 0.259 GCAAGTCCCGTTCTGTTAGTAGGTC SEQ ID NO. 566 TAPBPL 218747_s_at 0.259 CAGAGACGGCAAGCACCTACAGGAC SEQ ID NO. 567 LBR 201795_at 0.258 AAAGTGGTGGCGTTTTCTGTACTGG SEQ ID NO. 568 SP110 208392_x_at 0.258 ATGACCCTAGGAGAGCTGCTGAAGC SEQ ID NO. 569 RGPD3 210676_x_at 0.258 AGGAGCCTCCATTATGGCATGCTGA SEQ ID NO. RGPD4 570 RGPD5 RGPD6 RGPD8 CBWD1 220175_s_at 0.257 GATTGTCCAGGGTGTCCATGAGCTC SEQ ID NO. CBWD2 571 CBWD3 CBWD5 CBWD6 CBWD7 LOC100653334 ATP5D 203926_x_at 0.255 GATCCAGATCCGAATCGAGGCCAAC SEQ ID NO. 572 IGJ 212592_at 0.255 AAACATGTTCTAGAACTAGTTACAA SEQ ID NO. 573 RPLP0 214167_s_at 0.255 CCAGCCCAGAACACTGGTCTCGGGC SEQ ID NO. 574 USH1C 211184_s_at 0.254 ACACACACCAGATGGCATCCTTGGG SEQ ID NO. 575 PTPRCAP 204960_at 0.253 CCTCCATGTCACCGCACTGTAGAGG SEQ ID NO. 576 AARSD1 222064_s_at 0.252 ACCTGAATCTGCTCAGAGACCTGGC SEQ ID NO. PTGES3L- 577 AARSD1 SH2D1A 210116_at 0.251 ATGGGTGGTTTACCATTTCTTGAGG SEQ ID NO. 578

TABLE 6 Genes predicting resistance to oxaliplatin ranked in order of correlation coefficient (CC). Affymetrix IDs listed are publically available online at the Affymetrix NetAffx ™ Analysis Center. The probe sequence shows the sequence of one (median) of 11 probes listed by Affymetrix for that Affymetrix ID. Gene Affymerix ID CC Affymetrix Probe sequence SEQ ID NO. LPP 202822_at −0.51 CATTTCTTGGGATCGCTCGTTTGGT SEQ ID NO. 579 RHOC 200885_at −0.495 AGAACAAGCGTCGGAGGGGCTGTCC SEQ ID NO. 580 CAPN2 208683_at −0.483 AATCAAGTTCTTGACCCTATTCGGC SEQ ID NO. 581 FLNA 200859_x_at −0.469 TCTCGGCTTTCACTTGGGCAGAGGG SEQ ID NO. 582 WDR1 200609_s_at −0.467 AGTGTGTGACTCACACCTTGTGGCT SEQ ID NO. 583 FLNA 214752_x_at −0.465 CCCCCTGCGAGGAGATCCTGGTGAA SEQ ID NO. 584 ACTN1 208637_x_at −0.458 GGCGCTGTACGGCGAGAGTGACCTC SEQ ID NO. 585 CNN3 201445_at −0.457 TCTTCCCTCAATAGTTGCCTTTTAG SEQ ID NO. 586 FLNA 213746_s_at −0.456 GAGCAGCTTCACAGTAGACTGCAGC SEQ ID NO. 587 ACTN1 208636_at −0.455 AAATCCCCTCAGAGGTGTGACTAGT SEQ ID NO. 588 ALCAM 201952_at −0.44 TTCGGCTCTCCAATTTAACTCTTTG SEQ ID NO. 589 CD44 212063_at −0.438 TGTCTCCTGAAGACTTCCCTTAAAA SEQ ID NO. 590 CAV2 203323_at −0.437 GATGAGCAGACTTCTCGGAATTCAT SEQ ID NO. 591 PRSS23 202458_at −0.435 AACGTGGCTGTCAGAATCACTCCTC SEQ ID NO. 592 F3 204363_at −0.427 GACATTGGTATTCTGGGCAGCTTCC SEQ ID NO. 593 RAB31 217763_s_at −0.425 GTGCCATCGTGGTTGAGACAAGTGC SEQ ID NO. 594 ACTN4 200601_at −0.423 GAGGAGCTGAGTTGGCAGACCGGGC SEQ ID NO. 595 CAV2 203324_s_at −0.423 GAGAATATACAATGATCCTGGAAAT SEQ ID NO. 596 CYR61 210764_s_at −0.423 GCCAATGAAGCAGCGTTTCCCTTCT SEQ ID NO. 597 LMNA 212086_x_at −0.422 CAGTGACTGTGGTTGAGGACGACGA SEQ ID NO. 598 PSMD2 200830_at −0.419 CAGTGTTGTTGGCCCACGGGGAACG SEQ ID NO. 599 FKBP9 212169_at −0.415 AATAACCACATGGCTACCTTCTATC SEQ ID NO. 600 CYR61 201289_at −0.414 GCATTCCATCCCTTCCTGAAGGGGG SEQ ID NO. 601 WDR1 200611_s_at −0.413 AGGAGTGGACAATCACCTACTGAGG SEQ ID NO. 602 CAV1 203065_s_at −0.413 GGTGCCAATTTCAAGTTCCAAGTTG SEQ ID NO. 603 CAV1 212097_at −0.41 AATTTTTTATCATGCATGTCCTGTA SEQ ID NO. 604 CYP1B1 202436_s_at −0.409 GTGCTTGGAGTTTACCTGGCTTATT SEQ ID NO. 605 CD44 204489_s_at −0.408 GTGTGCTATGGATGGCTTCTAACAA SEQ ID NO. 606 COTL1 221059_s_at −0.408 GCACATTTGATATAGCTCTTTTTCT SEQ ID NO. 607 EPAS1 200878_at −0.407 CCAAGCTTCATATTAACCCTACCTG SEQ ID NO. LOC100652809 608 RAB31 217762_s_at −0.406 AACTGTTAGCAAGCGGCATTTGGAT SEQ ID NO. 609 RAB31 217764_s_at −0.406 AGACCCTGTAGTCCAGTGGTGCTGC SEQ ID NO. 610 RRBP1 201206_s_at −0.405 GACCCCGTTCAGCTGAAGACGCAGC SEQ ID NO. 611 CKAP4 200999_s_at −0.404 GGGAATGCAGGCCAAGTCCTTTTAT SEQ ID NO. 612 RND3 212724_at −0.404 ATAGCTGGCGAGTGCTTTCTGTATT SEQ ID NO. 613 CD44 209835_x_at −0.403 GGACACCCCAAATTCCAGAATGGCT SEQ ID NO. 614 LOXL2 202998_s_at −0.402 GTGTAAGTGACTCATCTTCCTGTTG SEQ ID NO. 615 LEPROT 202378_s_at −0.401 ACATGTGCACATGCGGCATTTTACT SEQ ID NO. 616 ATP2B4 212135_s_at −0.4 GTGGAAAAGCCTCTAAATGCATCCC SEQ ID NO. 617 TMEM158 213338_at −0.399 AAAGCAAGGTTTGTGCTGCGCTTCC SEQ ID NO. 618 ANXA2 210427_x_at −0.398 ACCAGCTTGCGAATAACAGTCCCCG SEQ ID NO. 619 S100A11 200660_at −0.397 AATACAGAACTAGCTGCCTTCACAA SEQ ID NO. 620 SDC4 202071_at −0.397 CAGCGAGAGCATGTCCATCTGTTGG SEQ ID NO. 621 PEA15 200787_s_at −0.396 CACCCACCTGTACTCTGGAGAGACT SEQ ID NO. 622 CD44 212014_x_at −0.395 GAGTCGTCAGAAACTCCAGACCAGT SEQ ID NO. 623 FNDC3B 218618_s_at −0.395 CAACACAGACTACAGGTTCCGCGTA SEQ ID NO. 624 LOX 204298_s_at −0.394 TCATGCGTATGCCTCAGGCTGCACA SEQ ID NO. 625 ANXA2 213503_x_at −0.394 CAGAAAGCGCTGCTGTACCTGTGTG SEQ ID NO. 626 COL4A1 211980_at −0.393 CATTAGTATTCCTCATTCTGCATCC SEQ ID NO. 627 YPEL5 217783_s_at −0.389 AACTGTACTTTGTACCCTCACATAC SEQ ID NO. 628 TNFRSF12A 218368_s_at −0.384 AACACTAGGGGCTGGCCCACTAGGA SEQ ID NO. 629 PDLIM7 203370_s_at −0.382 CAAGACGCCCATCCGGAACAGGGCC SEQ ID NO. 630 CD44 204490_s_at −0.382 GGGAGCTGGGACACTTAACAGATGC SEQ ID NO. 631 ANXA2 201590_x_at −0.381 GCTGATCGGCTGTATGACTCCATGA SEQ ID NO. 632 MAP1B 212233_at −0.381 GTGGCAGTTCAGAGACACGCTTTTC SEQ ID NO. 633 EXT1 201995_at −0.38 ATACCGAGACATTGAGCGACTTTGA SEQ ID NO. 634 IL6ST 212195_at −0.379 TTTCTTGAACACAGGCTTTGTCTGA SEQ ID NO. 635 CAST 212586_at −0.379 AAGCAGCCCTTTTTACAGTCTAGTT SEQ ID NO. 636 SGCE 204688_at −0.378 CTTGCTTATATCATGTGCTGCCGAC SEQ ID NO. 637 LEPRE1 220750_s_at −0.378 GATGAGCTATGACAGCGTCCAGGTC SEQ ID NO. 638 CYP1B1 202437_s_at −0.376 CTCATTACTTATACTGGGACACCAT SEQ ID NO. 639 CALU 200757_s_at −0.375 GGTATAATGTAACTTCACCCCAGCC SEQ ID NO. 640 BHLHE40 201170_s_at −0.375 GGCATATGGAGTGTCCTTATTGCTA SEQ ID NO. 641 MAP1LC3B 208786_s_at −0.372 GTACTTGCATGGGGTTCACTATTTA SEQ ID NO. 642 MYOF 201798_s_at −0.37 GGCTTCATTTCAAGAGTCATCCAGC SEQ ID NO. 643 PTRF 208790_s_at −0.368 CCCCGCTTGGACACAGTCCGAGTGG SEQ ID NO. 644 TRAM2 202369_s_at −0.367 GTCACTCTGCCTAAAAGCACTCTAG SEQ ID NO. 645 C20orf3 206656_s_at −0.365 GCTCCTTGCACTTGGAACAGGGCTC SEQ ID NO. 646 TPM4 209344_at −0.364 GTCATAACCCACAGATAGATCAACC SEQ ID NO. 647 S100A10 200872_at −0.362 TCAAAAAGACCCTCTGGCTGTGGAC SEQ ID NO. 648 FAM50A 203262_s_at −0.362 GCGCTCGAGATCCTTCGGAAAGACT SEQ ID NO. 649 PTRF 208789_at −0.362 CCAGGTTCTCAAGACACGAGTCCCC SEQ ID NO. 650 ACTB ACTB AFFX- −0.362 GAAGGATTCCTATGTGGGCGACGAG SEQ ID NO. LOC100505829 HSAC07/X00351_5_at 651 LRP12 219631_at −0.361 TGGACCCTAGGGATTTGCACTAAAA SEQ ID NO. 652 PPIC 204517_at −0.357 GAACTTAAATATATCCCCTTCCTCA SEQ ID NO. 653 MYOF 211864_s_at −0.357 TACCAAATCGACCAGAAACCTCCTT SEQ ID NO. 654 LGALS1 201105_at −0.355 GCTTCGTGCTGAACCTGGGCAAAGA SEQ ID NO. 655 LAMB1 201505_at −0.355 AAGAGTCAGCTGATGCCAGAAGGAA SEQ ID NO. 656 FAM171A1 212771_at −0.355 GTGTAACGTGGGTTCTGTTTAGCGA SEQ ID NO. 657 PTPRK 203038_at −0.354 CCTGTGGCCCAGCACTGGTCAAGAA SEQ ID NO. 658 GRB10 209409_at −0.353 AACCTTTATTCCATGTGCTTTGCTT SEQ ID NO. 659 GALNT2 217788_s_at −0.352 GACTTACTGCGGTTGCGTTAGTTTC SEQ ID NO. 660 CDH11 207173_x_at −0.351 AGTTCTGAGCTGTAATTTCGCCTTA SEQ ID NO. 661 LOXL2 202997_s_at −0.35 TCTCAGGGCTGCAACCACGAGGAGG SEQ ID NO. 662 MAPK1 212271_at −0.348 GTGGAGTTGACTCGGTGTTCTGTCC SEQ ID NO. 663 LDLR 202068_s_at −0.347 TTGTTCAGTGACTATTCTCGGGGCC SEQ ID NO. 664 CD44 210916_s_at −0.347 AAAATGGTCGCTACAGCATCTCTCG SEQ ID NO. 665 MXRA7 212509_s_at −0.347 GATCAGTCTCAAATGGGTTTCTTGG SEQ ID NO. 666 PLOD2 202620_s_at −0.346 TTATCAAGTGTCAAGATCAGCAAGT SEQ ID NO. 667 C19orf10 221739_at −0.345 CATCCTTCATGAGCCTGCAGAACTG SEQ ID NO. 668 CD59 200983_x_at −0.344 GTCTTCTGCCATTCAGGTCATAGCC SEQ ID NO. 669 EGFR 201983_s_at −0.344 GTGTCAACAGCACATTCGACAGCCC SEQ ID NO. 670 PLAU 205479_s_at −0.342 AGCAGCTGAGGTCTCTTGAGGGAGC SEQ ID NO. 671 TUBB6 209191_at −0.342 GATCACACCATGGAGACTTTCTACT SEQ ID NO. 672 MPRIP 214771_x_at −0.34 GACTTCCTGTTGTCTTCATCAAAGC SEQ ID NO. 673 RAB32 204214_s_at −0.339 GGAGAAGTATCCCTGCTAGTGGCTC SEQ ID NO. 674 MDFIC 211675_s_at −0.339 GTTACAGGCGGTGTCCTTTTAAATG SEQ ID NO. 675 PLAU 211668_s_at −0.336 GGAATTGTGAGCTGGGGCCGTGGAT SEQ ID NO. 676 CORO1C 221676_s_at −0.336 CCACCGCTCTCATTTCATGGAGTCT SEQ ID NO. 677 JAK1 201648_at −0.335 CTTTGGGGCAAGCTATTCCAGCACT SEQ ID NO. 678 TMBIM1 217730_at −0.335 CCTACTGTGGTACTGAAGACTTCTG SEQ ID NO. 679 VCAN 221731_x_at −0.335 GAAATGGTTTCACTTGCTCTTTGAC SEQ ID NO. 680 EPHA2 203499_at −0.334 AGGGACCGGTGCTGCAGGAGTGTCC SEQ ID NO. 681 EHD2 221870_at −0.334 TATTTAAGTGGAGCCCCTACGTAGA SEQ ID NO. 682 CRIM1 202552_s_at −0.333 GGTAATTAATCCATTCCTGGCATAA SEQ ID NO. 683 ULK2 204062_s_at −0.333 GTGGAGTTCCTACATGCAGTGAGTG SEQ ID NO. 684 KDELR3 204017_at −0.332 AGTAATCAGTCAATCCAATATCCCC SEQ ID NO. 685 RRAS 212647_at −0.332 GACGAGGCTTTTGAGCAGCTGGTGC SEQ ID NO. 686 CD59 200985_s_at −0.331 GGTAGGATATCTTGGCTTTGCCACA SEQ ID NO. 687 EHD2 45297_at −0.331 CTGAACGGAACAGTGTCCCCACAGA SEQ ID NO. 688 MYL9 201058_s_at −0.33 GCGTGCCGAGCTGAGGCAGATGTTC SEQ ID NO. 689 P4HA1 207543_s_at −0.33 GGGTGGTAATATTGGCATTCTGATT SEQ ID NO. 690 LAMB3 209270_at −0.33 AATGCTTTCCATCTCCAGGAGACTT SEQ ID NO. 691 PTPLA 219654_at −0.328 GACAGAGATCACTCGCTATTCCTTC SEQ ID NO. 692 NT5E 203939_at −0.327 ATAGGAAGTATGTTTGTTTCTTAGT SEQ ID NO. 693 OPTN 202074_s_at −0.326 GGAATATTCCGATTCATTCCTGCCC SEQ ID NO. 694 COL4A2 211966_at −0.326 TGTGGATCGGATATTCCTTCCTCAT SEQ ID NO. 695 CALU 200755_s_at −0.325 GGCAAGGAAAGATCCCTTTGCTCTA SEQ ID NO. 696 — 208540_x_at −0.325 GACTGAGCGGTGCATTGAGTCCCTG SEQ ID NO. 697 NR3C1 211671_s_at −0.325 ACCAGTGCCCAAAGTCTGTGTGATG SEQ ID NO. 698 NR3C1 201865_x_at −0.324 GAACTACGCTTGCTCATTTTTTCTT SEQ ID NO. 699 KDELR2 200699_at −0.323 TAACCTTGGCTATGTTACCACCGTT SEQ ID NO. 700 SEPT7 213151_s_at −0.323 TAATGACCAACCTGTTTCTACCTAT SEQ ID NO. 701 NFIB 209289_at −0.322 TGCACGAAGATATAATGTCCACATT SEQ ID NO. 702 AHNAK 211986_at −0.321 CAGACGGAGGTCAGGTCTTCCTCTT SEQ ID NO. 703 IL6ST 212196_at −0.321 GACAAAACTAGTTCACTCACTGCTT SEQ ID NO. 704 VCAN 204620_s_at −0.32 GGCTGGAAATGGTTTCACTTGCTCT SEQ ID NO. 705 SCRN1 201462_at −0.319 AGCACAAGCTTATGCTTCCCGTAGC SEQ ID NO. 706 MARCKS 201670_s_at −0.319 CTTTGTCAATCTATGGACATGCCCA SEQ ID NO. 707 TPM4 212481_s_at −0.319 TGCCATCTTCGCTTTGCTGGAAATG SEQ ID NO. 708 ANXA2P2 208816_x_at −0.317 CAGAAAGCGCTGCTGTACCTGTGTG SEQ ID NO. 709 MECOM 221884_at −0.317 AGTCCAAATCGCAGGCATATGCTAT SEQ ID NO. 710 MVP 202180_s_at −0.316 AGACAACCACGTGGTGCCTGTACTG SEQ ID NO. 711 NFIB 209290_s_at −0.316 GAATCACTATTCCTGGTTATCTCAC SEQ ID NO. 712 FAM190B 209379_s_at −0.316 GTGGGCACCAATCTACAACTATGTC SEQ ID NO. 713 FOSL1 204420_at −0.315 AGGGCAGCTGCTATTTATTTTCCTA SEQ ID NO. 714 PLAUR 210845_s_at −0.314 TCTCCTCTGGACCTAAACCTGAAAT SEQ ID NO. 715 GRB10 210999_s_at −0.314 GAACTCTTGCCCTGGAATAATCTTG SEQ ID NO. 716 TAGLN2 200916_at −0.312 AGCTGTGGCTGCAGGAACTTAATTT SEQ ID NO. 717 COL6A1 212091_s_at −0.312 TCACAGCGGGCAGGACGGACCCCGC SEQ ID NO. 718 RRBP1 201204_s_at −0.309 GCCCCAGTTTGTAAATGAACCTGTG SEQ ID NO. 719 TXNRD1 201266_at −0.309 TGGCATTTAGGCAGCAGAGCCCCTG SEQ ID NO. 720 AURKA 204092_s_at −0.309 TTTTTTCTCTGGTGGCATTCCTTTA SEQ ID NO. 721 RRAS2 212589_at −0.309 TCAAGTGTGTACAACAGTCCCATGA SEQ ID NO. 722 LRP12 220253_s_at −0.308 CCTGATACTGTAGTTCACTGTAGAA SEQ ID NO. 723 NPC1 202679_at −0.306 TCTTCACAGTGTTCCCCTAGAAAGG SEQ ID NO. 724 AXL 202686_s_at −0.306 AGATTCTAACGGTCTGTTCTGTTTC SEQ ID NO. 725 GATA6 210002_at −0.306 GCGTTGCAGCAATCAGTGTTAAATC SEQ ID NO. 726 CAMSAP2 212765_at −0.305 GAGCATTGCTTACAGGTTTTTTGTT SEQ ID NO. 727 ZDHHC7 218606_at −0.305 GTCTGAGGGTCTTCCTTTATGCTTG SEQ ID NO. 728 HK1 200697_at −0.304 AATCGTGTGTCCGTGGAACCAGTCC SEQ ID NO. 729 MARCKS 201668_x_at −0.303 TGCTTTTTGATCTCTTCGACTAAAA SEQ ID NO. 730 NFIB 213032_at −0.303 GAAGTATGGCTTTTTATGCATCCTT SEQ ID NO. 731 ATP1B1 201242_s_at −0.302 ATATGCTTTACACTAGCTTTCTGCA SEQ ID NO. 732 BASP1 202391_at −0.302 AGTGACAAACATTCTCTCATCCTAC SEQ ID NO. 733 BCL6 203140_at −0.301 AAACTGCGTTAAAGGCTCGATTTTG SEQ ID NO. 734 ID3 207826_s_at −0.301 GTGGCCTGAAGAGCCAGAGCTAGCT SEQ ID NO. 735 RRAS2 212590_at −0.301 AATGATCACCATGTTAGCCTTAGAC SEQ ID NO. 736 SPATS2L 222154_s_at −0.301 TTTTCACTCAGTTTTGGTTCCCTGC SEQ ID NO. 737 PMP22 210139_s_at −0.3 GACCGTGAGTTCCTAGAGCTTGGCT SEQ ID NO. 738 CDC14B 221556_at −0.3 ATCCGATGATAGTACTGCAGTTTTC SEQ ID NO. 739 FHL2 202949_s_at −0.299 CTCACCCAGGCAATCTTGCCTTCTG SEQ ID NO. 740 PRNP 201300_s_at −0.298 AGCAGTTAACATCTGAAGTGTCTAA SEQ ID NO. 741 MARCKS 201669_s_at −0.298 AAATCTTGATATCCAGAAGCACATG SEQ ID NO. 742 ADAMTS1 222162_s_at −0.298 GACACAATGAGCTTAGTACCTCCAA SEQ ID NO. 743 KCMF1 217938_s_at −0.296 CTCTCCTAATACTCCACATTCAAAC SEQ ID NO. 744 CTSA 200661_at −0.295 TCCCGCAGCAGTTCCTGAATGGGGT SEQ ID NO. 745 TPBG 203476_at −0.295 AGGGGATTTGCTTCCTTGTTATGTA SEQ ID NO. 746 CCND1 208712_at −0.295 CGCAAGTCTGAGGGTCTGGGCGGCG SEQ ID NO. 747 CASK 211208_s_at −0.294 AATGTGATACTGTCTCTTTGAAGCA SEQ ID NO. 748 ZYX 200808_s_at −0.293 CTGACCCAGGACCCAACATGGTCTA SEQ ID NO. 749 VEGFA 210512_s_at −0.293 TCTACATACTAAATCTCTCTCCTTT SEQ ID NO. 750 HBXIP 202300_at −0.292 TTGATGCTCATATCTGTTCTTCAGC SEQ ID NO. 751 ZCCHC14 212655_at −0.292 ATTGCTCCACTGTTCACCAAGGAAG SEQ ID NO. 752 CDC42BPA 214464_at −0.292 TCCCACCTCACTGGATCTTGATGTT SEQ ID NO. 753 CD63 200663_at −0.29 CCCGACTCCTGCTGCATTAATGTTA SEQ ID NO. 754 ADAM9 202381_at −0.29 AAATATGTTGATTCATGGCTATAAT SEQ ID NO. 755 LIF 205266_at −0.29 GATGGTACAGATGTTCCTGCCTTAG SEQ ID NO. 756 SPTBN1 200671_s_at −0.289 ATGACAGTTTCACAACCTGCATTGA SEQ ID NO. 757 RBPMS 209488_s_at −0.289 AAGCTCACATCTAAACAGCCTGTAG SEQ ID NO. 758 DKK1 204602_at −0.288 TTACCCCATTTAATTCTAGAGTCTA SEQ ID NO. 759 TGFBR2 208944_at −0.288 TAGAGGCGCCTAGAAATTCCACTTG SEQ ID NO. 760 POFUT2 209578_s_at −0.288 AGGGCAACGCTAGACACAGAATCCG SEQ ID NO. 761 ARID5B 212614_at −0.288 GTGAGACCCATACCATTGCAATGAT SEQ ID NO. 762 PYGL 202990_at −0.287 GGAACGTGGAACCTTCAGATCTAAA SEQ ID NO. 763 LDOC1 204454_at −0.287 CACTTCTTTTTTCCTATGCACTGGT SEQ ID NO. 764 PPAP2B 212226_s_at −0.287 GCACCATCCCAGTGATGTTCTGGCA SEQ ID NO. 765 FTH1 214211_at −0.287 GCCGTTGTTCAGTTCTAATCACACT SEQ ID NO. 766 SVIL 202565_s_at −0.286 AGCTCTGCCACCAATATGTATCTTC SEQ ID NO. 767 PLEC 201373_at −0.285 CAGGTGGAGGTGTCAGGCTGCTGGC SEQ ID NO. 768 PHACTR2 204048_s_at −0.285 GTCAAAGCAACCATACTTCACCTAG SEQ ID NO. 769 FLNB 208613_s_at −0.285 GCCAGCGTCTAGTTAGCCCTGGCTC SEQ ID NO. 770 ZYX 215706_x_at −0.283 ACTGCTAGAGCCCAGACCTGAGTGA SEQ ID NO. 771 GJA1 201667_at −0.282 CTACGGTCATGTTCAGCTTCATTGC SEQ ID NO. 772 KCTD12 212192_at −0.282 CAGGCATCTGAAAACCTTATCTGCT SEQ ID NO. 773 RABAC1 203136_at −0.281 GGAGTCCAAGCTTGTGCTCTTTGGC SEQ ID NO. 774 SLC39A7 202667_s_at −0.28 ACATCAATCGTGTGTCCTGATTTGG SEQ ID NO. 775 ELF4 31845_at −0.28 AGTGCCTGAGGACCTTTGCTGTGTC SEQ ID NO. 776 SERPINH1 207714_s_at −0.278 TGGGGGGGAGGTGAGGTACCAGCCT SEQ ID NO. 777 MALT1 210017_at −0.277 TCGGCACTACTTCTATTCAGCATTG SEQ ID NO. 778 PPAP2B 212230_at −0.277 CCTTCTACTGAACCTTTGAGGAAAG SEQ ID NO. 779 NPC2 200701_at −0.276 GCATCTGGCCAATGAGTCTGCTGAG SEQ ID NO. 780 CD55 201925_s_at −0.276 GATCTGTAATGTTATTTCCACTTAT SEQ ID NO. 781 SYNJ2 212828_at −0.276 TGGTAGGATTCCCAGGTCAGCAGCA SEQ ID NO. 782 MICALL1 55081_at −0.276 TGCCCAGCAGCTCTTGGTCAAAGCA SEQ ID NO. 783 ITGA5 201389_at −0.275 GAAGCCAGGAATTTCCCAGGACCTG SEQ ID NO. 784 TFE3 212457_at −0.275 ATAAAAGCTAGGCGTGTTTGATGCG SEQ ID NO. 785 CREB3L1 213059_at −0.275 GCCGCTGGGCCTTTTTAATTGCCAA SEQ ID NO. 786 SOGA2 213358_at −0.275 ATGTGACTCAGTCTGTTCCACTGTA SEQ ID NO. 787 COL5A2 221729_at −0.275 GGTGCTATGCTTCTGTTATTATTCC SEQ ID NO. 788 TIMP1 201666_at −0.274 GACCACCTTATACCAGCGTTATGAG SEQ ID NO. 789 COL6A2 209156_s_at −0.274 TCACGGGCAACGACAGTCTGCACGA SEQ ID NO. 790 RYBP 201846_s_at −0.273 GAATTTCGCACCCTGACGATTACTC SEQ ID NO. 791 WNT5A 205990_s_at −0.273 ACATCCCCTCAGTTGCAGTGAATTG SEQ ID NO. 792 SEC61A1 217716_s_at −0.273 GGACTGTCACTGTGGACGCCAAAAT SEQ ID NO. 793 SNAPC1 205443_at −0.272 GGTCAAGGGCAAGTCAAAGCAACTA SEQ ID NO. 794 LAPTM4B 214039_s_at −0.272 TTTTTACCTTGACTACCTGAATTGC SEQ ID NO. 795 FOXN3 218031_s_at −0.272 CGTGAGATGCTCACGAGTACCCTTC SEQ ID NO. 796 PPP4R1 201594_s_at −0.271 CCAGCCCTGTGTGTGAATCGTTTGT SEQ ID NO. 797 YES1 202932_at −0.271 GACACTCTCTACCAAGAGGGTCTTC SEQ ID NO. 798 HABP4 209818_s_at −0.271 AGAGGCTCGAGAGCAGGCCATTTCC SEQ ID NO. 799 HSBP1 200941_at −0.27 GTGACTTAGGCAGGAGTCGACCTCC SEQ ID NO. 800 RCN1 201063_at −0.27 TATCAGATTCTTTCTTTTCGACTTT SEQ ID NO. 801 YWHAZ 200640_at −0.269 CAAGATTACCTTCCTGTTTTAGCCT SEQ ID NO. 802 VIM 201426_s_at −0.268 TGTGGATGTTTCCAAGCCTGACCTC SEQ ID NO. 803 ID1 208937_s_at −0.268 GTGCGCTGTCTGTCTGAGCAGAGCG SEQ ID NO. 804 ZNF264 205917_at −0.267 TTATTGACCTTCCATGGTCCTCACT SEQ ID NO. 805 CD55 201926_s_at −0.266 GTTGACAGGTTTGCTTGGGACGCTA SEQ ID NO. 806 CTNNAL1 202468_s_at −0.266 ACGGATGGGTCTCAGTTACAAATAA SEQ ID NO. 807 JUN 201466_s_at −0.265 AGGTGCTTATTCTCAAAGCAGGAAT SEQ ID NO. 808 VOPP1 208091_s_at −0.265 GACAACTGCGTGGGTCCAAACACTC SEQ ID NO. 809 IL8 202859_x_at −0.264 GCTGTGTTGGTAGTGCTGTGTTGAA SEQ ID NO. 810 AMOTL2 203002_at −0.264 TATCGTTTTTAGGTTTGGTATGTGT SEQ ID NO. 811 CETN2 209194_at −0.264 GCATTTCCACATATCCACAAACACA SEQ ID NO. 812 KRT14 209351_at −0.264 AAGGTCATGGATGTGCACGATGGCA SEQ ID NO. 813 IGFBP3 210095_s_at −0.264 GAGTCATTCTCATGCTTTTCTTTAT SEQ ID NO. 814 ZFP36L1 211962_s_at −0.264 GGACTGCAAATTGAGTTTCTTTCTC SEQ ID NO. 815 MAP7D1 217943_s_at −0.264 CTCAGTGCATTCGTGTGCTCGCACG SEQ ID NO. 816 DNAJB1 200664_s_at −0.263 GGACCTTTCTACCAGTTGTGGACCA SEQ ID NO. 817 RNH1 206050_s_at −0.263 CTGGTCCTGTACGACATTTACTGGT SEQ ID NO. 818 AMIG02 222108_at −0.263 GAGTAACTTCTTAAATCCCTGTTCT SEQ ID NO. 819 SPTBN1 212071_s_at −0.261 GTGCTCAGTCGTACGACCTGTACCT SEQ ID NO. 820 FHL1 201540_at −0.26 CAGGGCTGTCATCAACATGGATATG SEQ ID NO. 821 TUBB3 213476_x_at −0.26 GTGAAGGTGGCCGTGTGTGACATCC SEQ ID NO. 822 MGAT1 201126_s_at −0.258 TGAAGGGGGCAAGCAAGACCTCTCC SEQ ID NO. 823 KIF2C 209408_at −0.257 AGTGACATGGGACACTCCTTTTCTG SEQ ID NO. 824 SLC20A1 201920_at −0.256 AGAGCATGCTCTGCGTTGTTGGTTT SEQ ID NO. 825 TSPAN4 209263_x_at −0.256 ATATTTACGTATTCTCCAAAGCAGT SEQ ID NO. 826

In some aspects of the invention, one or more biomarkers of sensitivity and/or resistance to oxaliplatin are measured in a biological sample obtained from a subject (e.g., a subject suffering from or susceptible to a disease, disorder, or condition treatable with oxaliplatin, such as cancer, e.g., colon cancer) using, e.g., a microarray, sequencing, NanoString, a protein array, or PCR-based methods, such as those described herein. In certain embodiments, the microarray includes probes capable of recognizing the one or more biomarkers of sensitivity and/or resistance to oxaliplatin, such as probes at least about 15 nt in length that have, e.g., a sequence with at least 5 (e.g., at least 10) contiguous nucleotides that are complementary to or identical to the sequence(s) of the biomarker(s). In embodiments of any of the above aspects, any one of the biomarkers from Tables 5 and 6 can be used to assess a subject's sensitivity and/or resistance to treatment with oxaliplatin. Alternatively, a combination of any of the biomarkers of Tables 5 and 6 may be used. For example, combinations that include the top 5, 10, 15, or 20 biomarkers from Tables 5 and/or 6 may be used. In some embodiments, one or more biomarkers of sensitivity to oxaliplatin is selected from the group consisting of MRPL16, ANP32A, SRSF2, PDSS1, PRIM1, HNRNPA1, NDUFAB1, GLTSCR2, RNPS1, and ICAM2. In certain embodiments, the biomarkers include MRPL16 and one or more of the biomarkers selected from the group consisting of ANP32A, SRSF2, PDSS1, PRIM1, HNRNPA1, NDUFAB1, GLTSCR2, RNPS1, and ICAM2 (preferably ANP32A, SRSF2, PDSS1, and/or PRIM1). In some embodiments, one or more biomarkers of resistance to oxaliplatin is selected from the group consisting of LPP, RHOC, CAPN2, FLNA, WDR1, FLNA, ACTN1, CNN3, FLNA, and ACTN1 (preferably LPP, RHOC, CAPN2, FLNA, and/or WDR1). In particular embodiments, one or more biomarkers of resistance includes LPP.

Furthermore, a combination of any of the biomarkers of Tables 1, 2, 5, and 6 can be used to assess a subject's sensitivity and/or resistance to treatment with the combination of 5-FU and oxaliplatin, and a combination of any of the biomarkers of Tables 3-6 can be used to assess a subject's sensitivity and/or resistance to treatment with the combination of irinotecan and oxaliplatin. In some embodiments, a subject's sensitivity to combination treatment with oxaliplatin and 5-FU is assessed by determining an expression level (e.g., mRNA or protein expression) of one or more biomarkers of sensitivity and/or resistance to 5-FU (e.g., the biomarkers shown in Tables 1 and 2, respectively), and one or more biomarkers of sensitivity and/or resistance to oxaliplatin. In certain embodiments, the one or more biomarkers of resistance to 5-FU are selected from the group consisting of NT5E, CNN3, ACTN1, FLNA, ATP2B4, CYR61, LGALS1, RHOC, RAB32, and TMEM158, and the biomarker of sensitivity to oxaliplatin is MRPL16. In particular embodiments, the biomarkers of resistance to 5-FU include NT5E, CNN3, ACTN1, FLNA, and/or ATP2B4. In one embodiment, the biomarker of resistance to 5-FU is NT5E.

Biomarker Expression Analysis Methods, Devices, and Kits

The methods, devices, and kits of the invention can be used to predict the responsiveness (e.g., sensitivity or resistance) of a subject to a target drug of interest based on the expression levels (e.g., mRNA expression level or protein expression level) of one or more biomarkers of sensitivity and/or resistance in a biological sample obtained from the subject. The biological sample can include, for example, cells, tissue (e.g., a tissue sample obtained by biopsy), blood, serum, plasma, urine, sputum, cerebrospinal fluid, lymph tissue or fluid, or pancreatic fluid. In certain embodiments, the biological sample is fresh frozen or formalin-fixed paraffin embedded (FFPE) tissue obtained from the subject, such as a tumor sample (e.g., a biopsy). Numerous methods of determining biomarker expression levels, or expression profiling, are known in the art, including, but not limited to, polymerase chain reaction (PCR), reverse transcriptase PCR (RT-PCR), quantitative real-time PCR (qPCR), Northern blots, Western blots, Southern blots, microarrays, NanoString nCounter technologies (e.g., those described in U.S. Patent Application Nos. US 2011/0201515, US 2011/0229888, and US 2013/0017971, each of which is incorporated by reference in its entirety), next generation sequencing (e.g., RNA-Seq techniques), and proteomic techniques (e.g., mass spectrometry or protein arrays).

PCR-Based Techniques

Tissue or cell samples from mammals can be conveniently assayed for mRNA levels using Northern, dot blot or PCR analysis. For example, qPCR assays are well known in the art. In some embodiments, an mRNA corresponding to a biomarker of sensitivity or resistance can be detected in a biological sample by (a) producing cDNA from the sample by reverse transcription using at least one primer; (b) amplifying the cDNA so produced using a target polynucleotide as sense and antisense primers to amplify target cDNAs therein; and (c) detecting the presence of the amplified target cDNA using polynucleotide probes. In certain embodiments, primers and probes comprising the sequences described herein are used to detect expression of one or more genes, as described herein. In addition, such methods can include one or more steps that allow one to determine the levels of target mRNA in a biological sample (e.g., by simultaneously examining the levels a comparative control mRNA sequence of a “housekeeping” gene such as an actin family member or GAPDH). Optionally, the sequence of the amplified target cDNA can be determined. The primers for these assays may be labeled for detection according to methods known in the art.

Microarrays

Expression levels of biomarkers of sensitivity or resistance may be determined using high-throughput expression profiling platforms, such as microarrays. Microarray technology offers high resolution quantification of mRNA expression levels at a genomic or transcriptomic scale. In certain embodiments, a microarray for use in the methods of the invention for assessing the responsiveness of a subject to treatment with a target drug (e.g., 5-FU, oxaliplatin, and/or irinotecan, as well as analogs thereof, such as prodrugs, derivatives, metabolites, enantiomers, and combinations thereof) contains or is produced by generating oligonucleotide probes (e.g., DNA, cDNA, or RNA probes) capable of hybridizing to one or more biomarkers of sensitivity or resistance to a target drug of interest (e.g., one or more of the biomarkers of Tables 1-6) or their complement sequences (preferably the probe sequence is complementary to all or a portion of the biomarker sequence). For example, such biomarkers can include one or more (e.g., at least 5, 10, 15, or 20 or more (e.g., all)) 5-FU markers of Tables 1 and/or 2, one or more (e.g., at least 5, 10, 15, or 20 or more (e.g., all)) irinotecan markers of Tables 3 and/or 4, or one or more (e.g., at least 5, 10, 15, or 20 or more (e.g., all)) oxaliplatin markers of Tables 5 and/or 6. An oligonucleotide probe can be complementary or identical to a portion (e.g., at least 5, 10, 15, or 20 or more nucleic acid residues; preferably at least 15 contiguous nucleic acid residues) or the entirety of a biomarker sequence, or may have, e.g., about 75%, 80%, 85%, 90%, 95%, 99%, or 100% sequence identity to a sequence complementary or identical to a portion (e.g., at least 5, 10, 15, or 20 or more nucleic acid residues; preferably at least 15 contiguous nucleic acid residues) or the entirety of a biomarker sequence. A probe can have a length of, for example, about 5 nucleotides (nt), 10 nt, 15 nt, 20 nt, 25 nt, 30 nt, 50 nt, 75 nt, 100 nt, 150 nt, or 200 nt (preferably at least 15 nt). In certain embodiments, a probe is between 20-24 nt in length and/or has at least 85% sequence identity to a sequence complementary to a biomarker sequence. In other embodiments, a probe is between 20-24 nt in length and/or has at least 85% sequence identity to a sequence identical to a biomarker sequence.

In some embodiments, a microarray for use in the methods of assessing responsiveness to 5-FU includes probes about 15 nt in length, which are complementary to at least 5 contiguous nucleotides of the following biomarkers of resistance to 5-FU: NT5E, CNN3, ACTN1, FLNA, ATP2B4, CYR61, LGALS1, RHOC, RAB32, and TMEM158; and/or probes about 15 nt in length, which are complementary to at least 5 contiguous nucleotides of the following biomarkers of sensitivity to 5-FU: APRT, GSR, TUFM, MRPS2, MTHFD2, WDR59, ANP32B, PMM2, STOML2, and NDUFAB1. In certain embodiments, the biomarkers of resistance include NT5E, CNN3, ACTN1, FLNA, and ATP2B4; and/or the biomarkers of sensitivity include APRT, GSR, TUFM, MRPS2, and MTHFD2. In particular embodiments, the biomarker of resistance is NT5E.

In some embodiments, a microarray for use in the methods of assessing responsiveness to irinotecan includes probes about 15 nt in length, which are complementary to at least 5 contiguous nucleotides of the following biomarkers of resistance to irinotecan: CCND1, LGALS3, INPP4B, TMEM97, TCF7L2, SFN, LAPTM4B, LSR, SFN, and TMEM97; and/or probes about 15 nt in length, which are complementary to at least 5 contiguous nucleotides of the following biomarkers of sensitivity to irinotecan: PRF1, GZMB, PTPRC, PTPRC, PTPRCAP, PDE4DIP, ACAP1, PTPRC, S1PR1, and DOCK2. In certain embodiments, the biomarkers of resistance include: CCND1, LGALS3, INPP4B, TMEM97, and TCF7L2; and/or the biomarkers of sensitivity include: PRF1, GZMB, PTPRC, PTPRC, and PTPRCAP. In particular embodiments, the biomarker of sensitivity is PRF1.

In some embodiments, a microarray for use in the methods of assessing responsiveness to oxaliplatin includes probes about 15 nt in length, which are complementary to at least 5 contiguous nucleotides of the following biomarkers of resistance to oxaliplatin: LPP, RHOC, CAPN2, FLNA, WDR1, FLNA, ACTN1, CNN3, FLNA, and ACTN1; and/or probes about 15 nt in length, which are complementary to at least 5 contiguous nucleotides of the following biomarkers of sensitivity to oxaliplatin: MRPL16, ANP32A, SRSF2, PDSS1, PRIM1, HNRNPA1, NDUFAB1, GLTSCR2, RNPS1, and ICAM2. In certain embodiments, the biomarkers of resistance include: LPP, RHOC, CAPN2, FLNA, and WDR1. MRPL16, ANP32A, SRSF2, PDSS1, and PRIM1. In particular embodiments, the biomarker of sensitivity is MRPL16. In some embodiments, a microarray for predicting responsiveness (e.g., sensitivity) of a subject to combination treatment with oxaliplatin and 5-FU includes probes about 15 nt in length, which are complementary to at least 5 contiguous nucleotides of one or more biomarkers of resistance to 5-FU selected from the biomarkers of Table 2, and one or more probes about 15 nt in length, which are complementary to at least 5 contiguous nucleotides of MRPL16. In certain embodiments, the biomarkers of resistance to 5-FU are NT5E, CNN3, ACTN1, FLNA, ATP2B4, CYR61, LGALS1, RHOC, RAB32, and TMEM158. In particular embodiments, the biomarkers of resistance to 5-FU are NT5E, CNN3, ACTN1, FLNA, and ATP2B4. In one embodiment, the biomarker of resistance to 5-FU is NT5E.

In certain embodiments, a probe is single-stranded or double-stranded. In some embodiments, a probe is labeled (e.g., detectably labeled with a fluorescent molecule, dye molecule, small molecule, epitope tag, barcode sequence, polypeptide, or any other detectable molecule). Probes can be detectably labeled and immobilized on a solid support to form a microarray. Probes can be either prefabricated and spotted to the surface or directly synthesized on to the surface (in situ). The microarray can be configured such that the sequence and position of each member of the array is known. For example, a selection of genes whose expression correlate with the presence of a disease (e.g., colon cancer), an increased likelihood of developing the disease, or increased severity of the disease can be arrayed on a solid support. Hybridization of a labeled probe with a particular target nucleic acid (e.g., an mRNA corresponding to a biomarker of responsiveness (e.g., sensitivity and/or resistance) to a target drug) indicates that the sample from which the mRNA was derived expresses that gene (e.g., the biomarker of responsiveness to the target drug).

Differential gene expression analysis of disease tissue can provide valuable information. Microarray technology utilizes nucleic acid hybridization techniques and computing technology to evaluate the mRNA expression profile of thousands of genes within a single experiment (see, e.g., PCT Publication WO 01/75166; U.S. Pat. No. 5,700,637; U.S. Pat. No. 5,445,934; U.S. Pat. No. 5,807,522; Lockart, Nat. Biotechnol. 14: 1675-1680, 1996; and Cheung et al., Nat. Genet. 21(Suppl): 15-19, 1999). Thousands of genes are typically represented in a single array. In some embodiments, a microarray assay for determining the expression level of one or more biomarkers of drug responsiveness involves the following steps: 1) preparation of fluorescently labeled target from RNA isolated from a sample, 2) hybridization of the labeled target to the microarray, 3) washing and scanning of the array, 4) analysis of the scanned image and 5) generation of gene expression profiles. Commercially available microarray systems can be used, such as an Affymetric array (e.g., an Affymetrix GeneChip® system) or an Almac array. Details of various microarray methods can be found in the literature. See, for example, U.S. Pat. No. 6,232,068 and Pollack et al., Nat. Genet. 23: 41-46, 1999. In alternate embodiments, a protein array can be used to measure the protein expression level of one or more biomarkers of responsiveness (e.g., sensitivity and/or resistance) to a target drug (e.g., 5-FU, irinotecan, and oxaliplatin), such as one or more of the biomarkers listed in Tables 1-6.

Exemplary probe sequences suitable for use in the methods of the invention are provided in Tables 7-12 below.

TABLE 7 Genes and corresponding Almac probesets predicting sensitivity to 5-FU. There can be multiple Almac IDs/probesets associated with a given gene. Almac SEQ ID Gene Probe ID Probe Sequence NO ALG5 ADXCRIH.469.C1_at TTCTAAATGAGCTCGAGATCCACATGCTATAGCCATTTGATTAGGCCAAGGCTGTAGATCATT SEQ ID TAGCCCCTTTTCTAATTTCTCAACATCTGGAAACTTTGTGGCTCCATCAGCATCTGCCATAAG NO: GATCTTTTCTCCTCGAGAACTGAATATACCCATTCTAATCGCTCCACCTTTTTCACGATTCTT 1166 CACCAGGGTTATCACACGTACTTTGTCACTTTCATATTTCTGGCAATTTTTAAAAGCTACCTT TGAGGTCTGATCT ALG5 ADXCRIHRC.469.C1_s_at GTTCTAAATTAGTTCCATTCTGGAGCTGGCTACAAATGGGTAAAGACCTACTTTTTATACGAC SEQ ID TTCGATATTTGACTGGTGCCTGGAGGCTTGAGCAAACTCGGAAAATGAATTAGGTTGTTTGCA NO: 1313 ALG5 ADXCRSS.Hs#S11048289_at GAATTTTAACATAACGCATGCCCCTTATATTTAGCTCTATTTAAGCAAAATTTAGTGTCCTCT SEQ ID TAGTATGATTAGGCTTCTCAAAGTTGTACATATTCTGAACTTTTCAATAAACCTTTAAAAGAT NO: TTTTAATGTCAACTTTTTTAAAATCAGTTTCTAAAAATGAGATATTCTCATTGAAAATAAATA 2082 TTTTTATTAGTGATATTTAAATATTGAAAAACTATCTCTGCTTTTTCCCTCAGAATCAAATGG CTATA ANK3 ADXCRAG_NM_001149_s_at GGCAGCACGCTGTAAAATTATTACTGTATTGTGTACTGGCTATAAGATGTAGACACCTTTCAG SEQ ID TAAGCCAATCATTTGTAACCATTCTAGCAGTGTCATATTAGGTTAATAAGGCTGCTGTGTTTT NO: AAAGGGCATTTTTATTTGGGTTTTGGTGAAATTCTTTAATTTGTTGATTATATTCACATAAAA 1008 TCAGCATTCATTGACACATAGCTCTAATGACATATGTATGAAAAACCATACACTGGATGACCT AGTCGATTATTTAAGCA ANK3 ADXCRSS.Hs#S1861798_at AAAATGAATCTACTGCCTCCTCCGAAGCTAGTCCTTCAGATACTAGAAGACAATTATGCCCTC SEQ ID TTTATCAAAGGCCCTACTTAAACCAGTTCAGTGATAATCTATCTTCTATACCCGTTTTTCATA NO: AATAGAACCATGTGTTGTTTCTTGCATAATTATAGAAGTGTTCAAGAGAAACGAAGAGAGTGA 2097 GTGGCAGGACCATGGTGTGATGCAGGAGGAAGAGCTCTTGGCTAGAATCTGCTCCCAACTCTC CAACTAACTGTGAATCATTGAATTGTTACTTAATGCCTCTATAA ANK3 ADXCRPD.11257.C1_at ATTTCCTCAATCTAAGCCTCTGGTTTTAAGACACCTTTGACACTGGTTGTTGTTTCTGCACGT SEQ ID GTTTTCAGAGCGGGCTAACACCACTGCATGTAGCTGCACATTACGATAATCAGAAAGTGGCCC NO: TTCTGCTTTTGGACCAAGGAGCCTCACCTCACGCAGCCGCAAAGGTACCTATAATTCCACAGC 2298 CTAAGGAGACTGATGGGTAAGGTCTATCAGTCTCTATCTGCACATCTACTTCTGCTTCAGCAG GAGCACCCTCCTAGTTTAGCCACGACATGCCGG ANK3 ADXCRAD_BX092880_at TGTGAATGAGCAAAGATTCTGTCTTGGTGACACAGTAGTTCATATCAAATGAAATGTTTAATT SEQ ID GAAACCTTAGAAACTGTAACAAGGTATGAGGCACGATAAAGAAGAAAGAGAATGAAAGAATTA NO: AAAGGCTTCCTTCTCAGTCTCAAATTCCTACTGCCTTAAGAATTTTTAAATTAAAACCAGTTC 2582 TTCATAAGCAATCAGTGGCTGAGAATTTGAGGTTATAACCTGGCATGGATATATGTGACACA ANP32A ADXCRPAGD.232.C2_s_at CTTCATTTTTGTTACCTGATAGAATAGCTTTTCTTATGAGATATATATAATGTGATACTATGT SEQ ID TTGGATATTTTTGGTCTTAAAGCAAGACTCAGTGGTGTATCTTCATTAAAAGCTTCCTTTAAA NO: AAAGTTACAGAGTTACTAAAAAAACAAGTACCCAAACAATCAAGTTGGGCCAACCTTGGAACC 1921 TTGTTTTGAATATCTTTCATTGTTTTGTTTGTCGTATTGTAAAAAGAATGTATGGTTGAAAAC TCAGGAA ANP32A ADXCRAAD_AL547157_s_at AAGAAGGTTATAACGATGGAGAGGTAGATGACGAGGAAGATGAAGAAGAGCTTGGTGAAGAAG SEQ ID AA NO: 2357 ANP32A ADXCRAD_AL547157_x_at GGAGGATGAAGAAGGTTATAACGATGGAGAGGTAGATGACGAGGAAGATGAAGAAGAGCTTGG SEQ ID TGAAGAAGAAAGGGGTCAGAAGCGAAAACGAGAACCTGAAGATGAGGGAGAAGATGATGACTA NO: AGTGGATAACCTATTTTGAA 2358 ANP32A ADXCRAD_CN349881_s_at TTGTAAATAGCAACCTAAAGGCGTATTTTGGCACTGGTCTGGGGACATTCCCCATCTCTCATC SEQ ID CCTTTTCCCCCTTCACAGATGGTGGTGGGCTTCGCTCTACAAAGAGGACTCTGATGTTACTCT NO: TGAGCTTATGAGCCAGAGAGCTGAAAACCGCAGGCTTGTTGTGTTAAGTTACAAGGAAAATGG 2736 ATTTGGTAATTAAAATTAGAAGAAACACACCTTCAAACTTCAACTTCTTTAAAAGAAAAAAAA AACTGTCCTATCTTGTTCTGTAAAATATTAGAACGCTTTGT ANP32A ADXCRAD_T67821_at TTTAATGAAGATACACCACTGAGTCTTGCTTTAAGACCAAAAATATCCAAACATAGTATCACA SEQ ID TTATATATATCTCATANGAAAAGCTATTCTATCAGGNAACAAAAATGAAGCTTCCCCCTCACC NO: TAGCAGTTCATCTGGGAATGCATCTTGGAAAAGATCCAATGGCCTGTTGGACTCAAAGAAGCC 2799 ATCCCCAAAAAAATTGTATAAAAGGGTTTATTGAAATTTATCCAATGACCAACCGG ANP32A ADXCRAAD_T67821_x_at TTTAATGAAGATACACCACTGAGTCTTGCTTTAAGACCAAAAATATCCAAACATAGTATCACA SEQ ID TTATATATATCTCATANGAAAAGCTATTCTATCAGGNAACAAAAATGAAGCTTCCCCCTCACC NO: TAGCAGTTCATCTGGGAATGCATCTTGGAAAAGATCCAATGGCCTGTTGGACTCAAAGAAGCC 2800 ATCCCCAAAAAAATTGTATAAAAGGGTTTATTGAAATTTATCCAATGACCAACCGG ANP32B ADXCRIH.2787.C1_s_at ACATTCCGCCTTCCTTCCATGTAGTCCCTCTTGGTAATCTACCACCAAGCTTGTGGACTTCAC SEQ ID TCCAACAAAATTGTAAGCGTTGTTAGGTTTTTGTGTAAGATTCTTGCTGTAGCGTGGATAGCT NO: GTGATTGGTGAGTCAACCGTCTGTGGCTACCAGTTACACTGAGATTGTAACAGCATTTTTACT 1143 TTCT APRT ADXCRIH.1533.C1_s_at GTGGAGCTGACCTCGCTTAAGGGCAGGGAGAAGCTGGCACCTGTACCCTTCTTCTCTCTCCTG SEQ ID CAGTATGAGTGACCACA NO: 1201 ATHL1 ADXCRIH.1963.C1_s_at GATGTTCGCAGGAAAAATCTGGAGATTTACGAGGCTGTGACGTCCCCCCAGGGCCCCGCCATG SEQ ID ACCTGGAGCATGTTTGCTGTGGGCTGGATGGAGCTGAAGGACGCAGTGCGGGCCCGGGGCCTC NO: CTGGACAGGAGCTTTGCCAACATGGCTGAACCCTTCAAGGTGTGGACGGAGAATGCAGACGGG 1222 TCAGCGCTGTGAACTTCCTGACAGGCATGGGGGGCTTCCTGCAGGCGGTGGTCTTCGGGTGCA CGGGGGTTCAGGGTCACCCGAGCGGGTGTGACCTTTGAC ATHL1 ADXCRAD_AJ708476_s_at AGTGGGATGGCTCTCTTCCCTCAGCCACGCCGCTTGTGAGGACAGAGGTGGGGGAGTGGGAAG SEQ ID TGGGAAGTCACCAGAGAACAGGAGAGGGATTTGAGGGCGCGACCCCAGCGCTCTCCACGGACC NO: AGCCAGAGGGACTGGAGCCAGGTGTGCATGGGTTCAAGGCCCTGGCCCTGCCCAGCCTCTGTC 1756 TTGGGAGCTCAGCCCCAGGGTTCGGTCGTCAGCAGTTTCCCAAGAACAAGATGTGATGGCATC TGCTGCTGAAACCCTGATGAGGACCAGGCCCC ATIC ADXCRAD_BU189824_at TCTTCCCTTTCCGAGATAACGTAGACAGAGCTAAAAGGAGTGGTGTGGCGTACATTGCGGCTC SEQ ID CCTCCGGTTCTGCTGCTGACAAAGTTGTGATTGAGGCCTGCGACGAACTGGGAATCATCCTCG NO: CTCATACGAACCTTCGGCTCTTCCACCACTGATTTTACCACACACTGTTTTTTGGCTTGCTTA 2723 TGTGTAGGTGAACAGTCACGCCTGAAACTTTGAGGATAACTTT CALML4 ADXCRAG_NM_033429_s_at TACAAACTGACATTGTCTACTATACATTTTTAAAAGCCATTTTACTGGTTTGGCATGCGGTAT SEQ ID GGAAATTCTAAGAGAGAAAGTTTTAAGGCAATGAATCACAGATTTAAGTTCATGGAATTTATG NO: GTAACTTTATCTGTTTATGTACATTTTCCCCTTTGTTAAACAATTAACAGCAGCACACTCTGG 1048 GACCACCAGCTATTTTCCCTCTCTTTCTGAAATCTAAGCTTTGT CALML4 RDCR490_C03_at GGGAGCAGCACGAACTCCTGAAGACTTGGGAGCGTCAGCAGCTTCTGCGGAAGGGGTGGGGCT SEQ ID GAGGGTGGAGAGAGGAAGGGAAGGAAGAAAAGGGGAGCCTTCCTGGCCAGGGTAACCGGCACT NO: AAGAGGCCTCACTCCAAGCCCCCGAGGAGCCTGTGGTGGGGCTGGAGACCCGGGCTCAGCCCC 1373 TCCACCACCCTTAAAGTCCTCAGAAGGTGGGAACTGAACTGGGCACAGGCTGGGAAACCGGCT GTGCGCTGGGCACTTGGAT CALML RDCR490_C03_x_at GAGCAGCACGAACTCCTGAAGACTTGGGAGCGTCAGCAGCTTCTGCGGAAGGGGTGGGGCTGA SEQ ID GGGTGGAGAGAGGAAGGGAAGGAAGAAAAGGGGAGCCTTCCTGGCCAGGGTAACCGGCACTAA NO: GAGGCCTCACTCCAAGCCCCCGAGGAGCCTGTGGTGGGGCTGGAGACCCGGGCTCAGCCCCTC 1374 CACCACCCTTAAAGTCCTCAGAAGGTGGGAACTGAACTGGGCACAGGCTGGGAAACCGGCTGT GCGCTGGGCACTTGGATTTTGCCAGCTGC CALML4 ADXCRAD_BX431388_s_at GAAGCAGATATCGAACCCAATGGCAAAGTGAAGTATGATGAATTTATCCACAAGATCACCCTT SEQ ID CCTGGACGGGACTATTGAAGGAGGAGAATGGGAGAGCCTCCCCTGGGCCTGAAAACTTGGAGC NO: AATTAATTTTTTTTAAAAAGTGTTCTTTTCACTTGGGAGAGATGGCAAACACAGTGGCAAGAC 1753 AACATTACCCAACTATAGAAGAGAGGCTAACTAGCAACAATAATAGATGATTTCAGCCATGGT ATGAGTAGATCTTTAA CALML4A ADXCRSS.Hs#S2988186_at ACGTCTTTCCCGCTCACTGTAGCTGCCACCCATTCTTTTTAATCCCCAGAGAGCATACAGATG SEQ ID AGCCCCAGTGGGCCATCTCAGCCACATAGGGGACAGGCCGGGGAGAGGATCTAGAGCTGGCCC NO: AGGAAAGGAGGCCCTTTTCATTTTGAGGGAGGCCTCCCATCAGAGAAGGGTCCAGTCCTGCCC 2163 CGACCCTGTCCTTCCCATGATACCCACAATCCCAGGGTGACCTGTCTCCAGGGCAGAAGTGAC AGACGAGGGCTAGGAGACTGGCTGAGGCCTAAGTCCTCTGCAAT CALML4 ADXCRAD_BQ928122_at CTGGCCTGCAGGAAAGGAGCGCCCAGCTGCGCGCCTGGGCCGCCCGTCGCTCCCAGTGCTGCC SEQ ID GCCCTCGCGTTGCCTCCATGGCTGCCCCGCAGGCCCCTCGGCCCTGCCTTTTCCGAGGAAAAA NO: CGGTTCAGCTCGGTG 2341 CALML4 ADXCRAD_BQ928122_x_at AGGTCGAGGTGGAAGGGAGCCGTGCGGGCAGCCTCATCAGCGCTCACAGAGCCATGCCTGGCC SEQ ID TGCAGGAAAGGAGCGCCCAGCTGCGCGCCTGGGCCGCCCGTCGCTCCCAGTGCTGCCGCCCTC NO: GCGTTGCCTCCATGGCTGCCCCGCAGGCCCCTCGGCCCTGCCTTTTCCGAGGAAAAACGGTTC 2342 AGCTCGGTG CALML4 ADXCRAD_AI348378_at AGATCTTGAAAGTTTTATGTGTTTAAAATTGAAATTGTCTAAAAAAATGCTCTTTCCACATTA SEQ ID ATTTAGTTAGGATATATTTTCACTCCATTTCAGACACTTGACTCA NO: 2835 CALML4 ADXCRAD_AW025529_at ACCGCAGGTCGGACGCCATGACGTAACCTTTCTTCTCCTTGTCCACCATCAACATGGCTAGAA SEQ ID GAATTTCTTTCTTTGGGTCTTCTTGTTTTATTTGCATGTGCATAATGGTCAGAAAAGTGGAGA NO: AATCCAGCTCTCCATTTCCGTCTATCCCGTGGGTCTGCAGGTGCCGCTGCACCTCCCCTGGCG 2902 TTGGGCTGGCCCCCAGGCACCTCATGGCCACCATGAGGTCGGGGGCTTTATCTTCCCCCTCTG CTGCTGTCATACAAGGAGAAGCATTTCTTGTCTCATTAATTT CASP7 ADXCRPD.1914.C1_at GATAGTCTATGTATGTGTAAAACAATCTGTTTTGGCTTTATGTGCAAAATCTGTTATAGCTTT SEQ ID AAAATATATCTGGAACTTTTTAGATTATTCCAAGCCTTATTTTGAGTAAATATTTGTTACTTT NO: TAGTTCTATAAGTGAGGAAGAGTTTATGGCAAAGATTTTTGGCACTTTGTTTTCAAGATGGTG 1529 TTATCTTTTGAATTCTTGATAAATGACTGTTTTTTTCTGCCTAATAGTAACTGGTTAAAA CASP7 ADXCRPD.1914.C1_x_at GATAGTCTATGTATGTGTAAAACAATCTGTTTTGGCTTTATGTGCAAAATCTGTTATAGCTTT SEQ ID AAAATATATCTGGAACTTTTTAGATTATTCCAAGCCTTATTTTGAGTAAATATTTGTTACTTT NO: TAGTTCTATAAGTGAGGAAGAGTTTATGGCAAAGATTTTTGGCACTTTGTTTTCAAGATGGTG 1530 TTATCTTTTGAATTCTTGATAAATGACTGTTTTTTTCTGCCTAATAGTAACTGGTTA CASP7 ADXCRSS.Hs#S3017613_at GTGAATATGCTTACATCCCAGAGACTACATATATGGCAACAAAGAAAACAAAGTCCTGGCCCT SEQ ID CAGGGAGCTTCTAATCCAGTAACCACAATTTGGTGGTATGTTCACGGCATACAAGAAACAGTG NO: GAAGGTCTGTCAAGGTTTACAACAATGAAAATTTCCCCCTAAATTCCTAGCAGGTCGCAAAGT 2181 GCTCATACGCAATTCAAAAGCAGCGACAACCTGGGGTATTAGGCTCTCTTTCTATGTCAGCAG GGATGCCCACATGGCAGATGCCCAA CCT3 ADXCRIH.1715.C1_at AGCTCTGTGAGGACATTATCCAACTGAAGCCCGATGTGGTCATCACTGAAAAGGGCATCTCAG SEQ ID ATTTAGCTCAGCACTACCTTATGCGGGCCAATATCACAGCCCATCCGCAGAGTCCGGAAGACA NO: GACAATAATCGCATTGCTAGAGCCTGTGGGGCCCCGGATAGTCGCCGACCAGAGGAACTGA 1125 CCT3 ADXCRIH.2536.C1_at AGGAATGACCTCTAGGGCCTGGGCAACAGCCCTGTATGGCCATTGTTCCACACCAGTCATGGC SEQ ID CTTGGATTTTTCTGTCAAGGCATGGGCCACAGCCATCTCGGAGGCCCCACCCCCTGGCACCAG NO: CTGAGGGTCCAGGAAACATTGCGACACACTTGCATGGCATCCTGAAGGTTGCGTTCTACTTCC 1209 GAGAAAATCTCTTTGCTA CCT3 ADXCRIRC.2536.C1_at HAGAAAGGCGATGACCAGAGCCGGCAAGGCGGGGCTCCTGATGCTGGCCAGGAGTGAGTGCTA SEQ ID GGCAAGGCTACTTCAATGCACAGAACCAGCAGAGTTTCCCCTTTTCCTGAGCCAGAGTGCCAG NO: GAACACTGTGGACGTCTTTGTTCAGAAGGGATCAGGTTGGGGGGCAGCCCCCAGTCCCTTTCT 1321 GTCCCAGCTCAGTTTTCCAAAAGACACTGACATGTAATTTTTCTC CLDN3 ADXCRIH.1252.C1_at TGCAGCCTTGCCTCGGAGGCCAGCCCACCCCCAGAAGCCAGGAAGCCCCCGCGCTGGACTGGG SEQ ID GCAGCTTCCCCAGCAGCCACGGCTTTGCGGGCCGGGCAGTCGACTTCGGGGCCCAGGGACCAA NO: CCTGCATGGACTGTGAAACCTCACCCTTCTGGAGCACGGGGCCTGGGTGACCGCCAATACTTG 2231 ACCACCCCGTCGAGCCCCATCGGGCCGCTGCCCCCATGCTCGCGCTGGGCAGGGACCGG CNOT1 ADXCRIH.3349.C1_at TTCCAGACAAAGGTTTTCTCTTTCATGTATTTACACAAGTTCAAAATGATATTCACAGCATCT SEQ ID TCTAAATTTTGGCCAAGAGTCAAAAAAATGCATTTAAACTTTGGAACGTGCCCACATAAGACA NO: GGAGGCTGATCCCAACAGTAGTTGGGGCAGATACCCACAAACCAAAGGGCTGGGAAAGTCAGG 1129 AAGAGTTGAAAGGATTCTTCAGTCAGTTTATGAACTCGGTGCAGTGAGACCTCTAGACTGACA CGTACAACAGAGATGCAGTTTCGTCTAACTGGCACCTGTCCCTTCGGA CNOT1 ADXCRIH.2766.C1_at TTTGTTGACAGATGCACCACCAGGGAATACTGACACCGATGATCTCATACCAAGGT SEQ ID NO: 1137 CNOT1 ADXCRIH.2766.C1_s_at GATTGCCCCAGCTGATGGAAGTAGTGCGATCCAACTATGAAGCAATGATTGATCGTGCTCATG SEQ ID GAGGCCCAAACTTTATGATGCAT NO: 1138 CNOT1 ADXCRIH.2766.C1_x_at GATTGCCCCAGCTGATGGAAGTAGTGCGATCCAACTATGAAGCAATGATTGATCGTGCTCATG SEQ ID GAGGCCCAAACTTTATGATGCATTCTGGGATCTCTCAAGCCTCAGAGTATGATGACCCTCCCA NO: GGCCTGAGGGAGAAGGCAGAGTATCTTCTGAGGGAATGGGTGAATCTCTACCATTTCAGCAGC 1139 AGCTGGCCGCGACAGTACCAAAGCTTTCTCTGCATTTGTTGACAGATGCACCACCAGGGAATA CTGACACCGATGATCTCATACCAAGGT CNOT1 ADXCRIHRC.3349.C1_s_at TAGGAAAGGGAACCAAATCTCATTAATTAATTGTTCTCCCCCATTACCCCACTGAATGAATGG SEQ ID CCATACAGGCTAAGCTGAATAATGACAAAGTTGAAAGGACCAATACAGCCCCTTTTATAAGGA NO: TTTTGAATGTTTTGCAAATGTATTGGTCCCTGTGTTGTATTTTGTAGCCTTTTCCTGGGCTTC 1309 AGCTCCCCTACTTCTTGTATGTGTATGCATACTGTAGCTAACCATTAAAGTCATG CNOT1 ADXCRPD.235.C1_at CCGGGACCACTGCAAACTGTCCGTATCCCTTTCCCTCCCCACAGAAAAACCCCGCGCCCAAAA SEQ ID ATCGGCCCTGTGCTGTCCC NO: 1502 CNOT1 ADXCRPD.6310.C1_s_at AGCTCCTGGCTTTGTATATGCCTGGCTTGAACTGATTTCCCATCGGATATTTATTGCAAGAAT SEQ ID GCTGGCACATACGCCACAGCAGAAGGGGTGGCCTATGTATGCACAGCTACTGATTGATCTTAT NO: TCAAATATTTAGCGCCTTTCCTTAGAAATGTGGAACTCACCAAACCTATGCAAATCCTCTACA 1741 AGGGCACTTCAAGAGTGCTGCTGGTTCTTTTGCATGAT CNOT1 ADXCRPD.12126.C1_at GGCCTGTCTGCAAGCATTAATGCAGGAGTGTTTTTCACGGAGCTAACAGAAAACATCTTCCAC SEQ ID TGTGTAAGTC NO: 2302 CNOT1 ADXCRPD.12126.C1_s_at ACTCCATTTGCCTTTGTTATTGACCTTGCTGCACTTGCTTCACGTCGTGAATACCTCAAACTT SEQ ID GATAAGTGGCTCACAGATAAAATTCGAGAGCATGGGGAGCCTTTTATCCAGGCGTGTATGACT NO: TTTTTAAAGAGACGGTGTCCTTCTATTTTGGGCGGACCTGCCCCAGAAAAAGACCAGCCCAAA 2303 AGTGCTCAACTTCCTCCAGAAACTTTGGCGACAATGTTGGCCTGT CNOT1 ADXCRPD.12126.C2_at CATGTTTCTTCCTTTCTCGTTAGGAAGAGCTTGGATTTGATTGAATCTCTGCTGAGGCTTGCA SEQ ID GAGGTTGGGCAGTATGAGCAAGTCAAACAGCTCTTCAGCTTCCCTATCAAACACTGTCCAGAC NO: ATGCTGGTATTGGCCTTACTACAAATTAACACCTCTCTGGCATACCTTGCGCCATGAACTTAT 2304 CTCCACTCTGATGCCAATTTTCCTTGGAACCATCCTAACTCAGCTATTATTTTGCACTATGCA TGGCATGGGCACGTAAGATGTGACACGTGGCATCTCTCAATACGG CNOT1 ADXCRPD.12126.C2_s_at GCTTGGATTTGATTGAATCTCTGCTGAGGCTTGCAGAGGTTGGGCAGTATGAGCAAGTCAAAC SEQ ID AGCTCTTCAGCTTCCCTATCAAACACTGTCCAGACATGCTGGTATTGGCCTTACTACAAATTA NO: ACACCTCTCTGGCATACCTTGCGCCATGAACTTATCTCCACTCTGATGCCAATTTTCCTTGGA 2305 ACCATCCTAACTCAGCTATTATTTTGCACTATGCATGGC CNOT1 ADXCRAD_NM_206999_at GGCTATTTCCTTGGTATAGGTACAAAACGTATTACTGCTTGTCTGTAATAATTTTTTTCTTTG SEQ ID TCTATATATGGCACTGGGCGTTACCACTTATTCTTAATAATCACCATATTTGTTTGATGTCTT NO: CCATCATTTTAGATTGTAATTCTGTGAGGCAAAGCATCATGTCTGTGTGTTTTTTTTTTTTTC 2757 TGTTATATTCTCAACACGATGTTTGACAGATAGTAGATACCCAA CYBA ADXCRIH.1394.C1_s_at ATTGCGAGCGGCATCTACCTACTGGCGGCTGTGCGTGGCGAGCAGTGGACGCCCATCGAGCCC SEQ ID AAGCCCCGGGAGCGGCCGCAGATCGGAGGCACCATCAAGCAGCCGCCCAGCAACCCCCCGCCG NO: CGGCCCCCGGCCGAGGCCCGCAAGAAGCCCAGCGAGGAGGAGGCTGCGGTGGCGGCGGGGGGA 1119 CCCCCGGGAGGTCCCCAGGTCAACCCCATCCCGGTGACCGACGAGGTCGTGTGACCTCGCCCC GGA DDC ADXCRAG_AY526322_at GATTATTCAGACTAATCTGTGGTCAATACAGAGCATCTTTATTTAAATACATATTCAAGTTAG SEQ ID TGTCAAAAAGAGTGCACAAAGTGCTGCTGGCACTGGAATTAGATGTTTCCTTACTGACCTCTG NO: GTATCTCCTGATAACAGGCCCCTCCTGCTTAGTGTTGGGAAAGTCCCAGATTGATCTAGACAC 910 AACTAACAGCTGATATGAAAGATTTGTCCTGGAATCACATGTCTCC DDC ADXCRAD_CD013938_s_at GAGGGTTGTGATTTTGTCTGCTTAGTATCTCATCAACAAAGAAATATTATTTGCTAATTAAAA SEQ ID AGTTAATCTTCATGGCCATAGCTTTTATTCATTAGCTGTGATTTTTGTTGATTAAAACATTAT NO: AGATTTTCATGTTCTTGCAGTCATCAGAAGTGGTAGGAAAGCCTCACTGATATATTTTCCAGG 1005 GCAATCAATGTTCACGCAACTTGAAATTATATCTGTGGTCTTCAAATTGTCTTTTGTCATGTG GCTAAATGCC DUSP2 ADXCRPD.6684.C1_s_at AGCTGTGACAACCAGGAGCCCTGTCTGTGGGTTCGTCTGCCCAGGGCCTGGAGCCCAAGCCCT SEQ ID GTGTTCCTGGGGAAGCTGGGGACTTGGGAAGTGATGGGTGTGTCATGTTGCGTGTGTCTGTCT NO: GTGAGCCTTTCACACCTGTGCTGGCGCTGGAAAATTATTTGTGCTCAGCTGACATTTAACACT 1779 CCCTCCCCCGCTTCCTCCTAGCCCTGTGGGCAGGGGTTGGAAACTTAGCACTTTATATTTATA EEF1B2 ADXCRIH.572.C1_s_at TAGATGTGAAACCTTGGGATGATGAGACAGATATGGCGAAATTAGAGGAGTGCGTCAGAAGCA SEQ ID TTCAAGCAGACGGCTTAGTCTGGGGCTCATCTAAACTAGTTCCAGTGGGATACGGAATTAAGA NO: AACTTCAAATACAGTGTGTAGTTGAAGATGATAAAGTTGGAACAGATATGCTGGAGGAGCAGA 2228 TCACTGCTTTTGAGGACTATGTGCAGTCCATGGATGTGGCTGCTTTCAACAAGATCTAAAATC CATCCTGG EEF1B2 ADXCRIH.572.C3_at GCTCTCGAAGTTTATCAGGATGTTCACATGACAAAACTGGACCCAGGCTACTTTAGTTTTGTT SEQ ID GGGATATTGTAAGCTAAATTTTTCTGTAACCTTAGAAGGCCAAGAGACTGAAGCCCTCCATTT NO: TTTCACAGAACAGGTAGAACATGGACAGCAGCAATTCAACTTTTCCCCACACTGCCCTGCCAA 2229 TGTGCCTCGACCTTGACCTGGGGGGCCCACCTCTGGGGTGAGAGGGTGGCTCATTCATTCAGT CCTTGGCCATTCTTCTGAAACTGCCAACAAGGGTG ETS2 ADXCRAG_AL832032_at CCCCCTTCAGTCGGCTCTCATTCTCCTTCCTGCTGCCCTGTGAAGAAGAACATATTTGCTTCC SEQ ID CCTTCTGCCATGAATGTAAGTTTCTTGAGGCGTCCCCAGCCATGCCAAACTGTG NO: 893 ETS2 ADXCRIH.651.C1_s_at GTATTTATCACTTGGACATCTGTTTATAATATAAACAGACATGTGACTGGGAACATCTTGCTG SEQ ID CCAAAAGAATCCTAGGCAGTGGCTCATTGTATGTGAGGTTGAACCACGTGAAATTGCCAATAT NO: TAGGCTGGCTTTTATCTACAAAGAAGGAGTTTCATGGGGTTCAGCCTAACAGTTATGGAAACT 1111 ACAGTCCTTATAAACCATTGGCATG ETS2 ADXCRPD.8805.C1_at ATTTGTCTGGCAAAATTAAGTTCTTTTTTCTTTAAAATGAACTTTTTTTCTTATTTCGAAGTG SEQ ID ATGTGTATGTAAAGAGGCAGTGTAGACTGGTGGTTAGGAGCACTCTGGAGTCAGAAGCCTGCT NO: TCAGAATCTTGGCTACCTCACTTACCAAGGATAGAGCTGTGGGGAGTTTACTTGTTCTCACTC 1449 TCTCTTCTTTTTTCCATCTGTAAAATGGCAAAAATAAACCACCTAAGTAAAATGGCCTCTGCG AGAGACCCATAAATTA ETS2 ADXCRPD.3556.C1_at GGTAAGATATGGCTACAAACAGATCAAAACTTCCACTTCAAGATGCTAGAAAGAAGC SEQ ID NO: 1597 ETS2 ADXCRPD.3844.C1_x_at CAACTTTATTTTGACTACTTTGATAACTTAAATAATTCTTTGTTACAGTGTTACTTCGTATTA SEQ ID GAGAGAATGTTTTTATTCTCAGGCGATAGATGCAAAAATATTTAAAGTGCAGCTCACTTTCAA NO: ACGGTTCAGCCAAATGTCGATGATTTTTGAATCTAAGTGGTGAGTATACAAATGTTCCTCGTA 1655 TTCATCTTTTATCTTTTTTGTATATTTGAAAATTTTTGGAATACAAAGTTGGAAAAAATAAAT CATGCCCAAAAGATTGCCAGTAG ETS2 ADXCRSS.Hs#S1228156_at ATTCTGCACATTTGGTTCTATGTCATTTGCCATAGTCTTAAGGACGTAGGTTCCATAATCATC SEQ ID CCTTATTCTGTAGAGGAGGCCCAAGGTTAGTGAGCAGAGGAAGGTTCCACTGTCGGGAACCGG NO: TGGTCTTCAAACTCCTGTGCTCCTCTTTTGATATCTTTCTGCTCATATATGTTGGAAACAGCC 2067 CAGCATGAGCAAAGCACCACCTCCTAGCCCCCAGCCTGTGCCAGCCCTGCAAAGAGGAAATAT GGCTCCACTCAGGGAGCCCATCAGCGACTCAGGGA ETS2 ADXCRSS.Hs#S2874408_at TTCCTCCTCAGCAACGGGCACAGGTCGTTCCAGTTTTGGCCAGGCGGTGGCGCTCGAGGCAAA SEQ ID CGGTGTCATGAAACGGTCACTGGATGCACTGACCCTGAAGATGCTCTCAAAGCACGAGTCCGT NO: TCATCAGAGAGTGGACTTGACACCCATCAGAAACATTCCCGGAGTGCGTTGGTGTGAAGGTGC 2072 GAGGAGAGTCGGGGAAGCATCCCGAAGCCCTGCTAGGCGAATGGGTACTGCTGAGATTACAGG GTCAGCACAAAGCA ETS2 ADXCRSS.Hs#S3746017_at CTCTTCTTATTTGAATACCCTTGACTTCCTCTCTTCCTATTTGAATACTCTTTCTTTCTCTTG SEQ ID CCTGATTGCTCTGGCCAGAACTTCCAGTACTGTGTTGAATAGGGGTGGTGAGAGAGAGCATCC NO: TTGTCCTTGTGCCGGTTTTCAAAGGGAATGCTTTCTGCTTTTACTCATTCGGTATGATACTGT 2200 CTATGGAT ETS2 ADXCRSS.Hs#S3746017_x_at ACAATTTGACCTTCTCTCTTCTTATTTGAATACCCTTGACTTCCTCTCTTCCTATTTGAATAC SEQ ID TCTTTCTTTCTCTTGCCTGATTGCTCTGGCCAGAACTTCCAGTACTGTGTTGAATAGGGGTGG NO: TGAGAGAGAGCATCCTTGTCCTTGTGCCGGTTTTCAAAGGGAATGCTTTCTGCTTTTACTCAT 2201 TCGGTATGATACTGTCTATGGAT ETS2 ADXCRSS.Hs#S3736200_at GGTTAATATCCATGCTATAAAGTTTTATTTTTTCATCAACAAAACTAATTGCATTGGCACTTT SEQ ID CAAAATGTTGTTTGCACATAAATGATTTATACTTAAGTATGAGTGTAACAATCTTGCCATCAG NO: GACCTGGTCTGTTGGGAGATATCAGTGAATGGAGCCTGGCTCTTCCAATGGGCAACCGTTGTT 2210 TGTTGGTGAAGCTGCCACCCTTGAGACCTGCCTGGTCTCCTTCCCACCTGTAGCTGGCTAAGT AGTGTCTCCCCACAATTCAC ETS2 ADXCRSS.Hs#S3738574_at CTTGCTCTAAGAATTGCCTGGACTAGCACTAACAGTGCTGACCTATGGAAGATCGTGTGAGCC SEQ ID ACTTAAGCAACTGCGAAAGTTCTAGTGGCCATATTAAAAAAGCAAAAAGAAACAGGTGAAGTT NO: AATTTTCTTATTTTACTTGGCCTCATATAGCAATTATCATTTCAATATGTAATCAATACATTA 2217 AAAATTATCAGGGAGACATTTTATATTCTCTGTTTCATACTAAGACTTCCAAATCTGGTGTGC ATGACTATACTCTGCTTGTCCTG ETS2 ADXCRIH.2576.C1_s_at GCAGGATTGAAAATGTCCAGGAAAGTGGCCAAGAAGCAGTGGCCTTATTGCATCCCAAACCAC SEQ ID GCCTCTTGACCGGCTGCCTCTCTTGTGGCAGCAACGGCACAGCTAATTCTACTCACAGTGCTT NO: TTAAGTGAAAATGGTCGAGAAAGAGGCACCAGGAAGCCGTCCTGGCGCCTGGCAGTCCGTGGG 2259 ACGGGATGGGTTCTGGCTGTTTGAGATTCTCAAAGGAGCGAGCATGTCGTGGACACACACAGA CTATTTTTAGAT ETS2 ADXCRIH.2576.C2_at ACAACCATGTCATTTCAGAAGTTAGTTTGTATATATTATAATAATCTTATAATTGTTCTCAGA SEQ ID ATCCCTTAACAGTTGTATTTAACAGAAATTGTATATTGTAATTTAAAATAATTATATAACTGT NO: ATTTGAAATAAGAATTCAGACATCTGAGGTTTTATTTCATTTTTCAATAGCACATATGGAATT 2260 TTGCAAAGATTTAATCTGCCAAGGGGCCGACTAAGAGACGTTGTAAAGTATGTATTATTCACA TTTAATAGACTTACAGGGATAACGCCTGTTGG ETS2 ADXCRAD_AI632259_x_at CTCCTGCTTCAGCCTGGGAGGCAGAGCTTGCAGTGAGCCGAGATTGCGCCACTGCACTCCAGC SEQ ID CTGGGAGACAGAGCGAGACTCCGTCTCAAAAAAACAAAACAAAACAAACAAACAAACAAAAAA NO: CAACAAAGCAATCAATACCAGANACATGAAAGAAAAATGCCAGTTCTCAGAGCTGTT 2831 ETS2 ADXCRAD_AV646177_at TGTAACCATTCTCAGCTGTTACATTTCTGCTCTTTATCCTTTTTTTTTTTTTTTTTGGTTTAA SEQ ID AAGCAGCGATCCATCAGCAACACCAAACTTGAAATTGATTTATGTGGAAAAACTTGGCTTGTC NO: TGCCATCTAACAAGCCCTGTTGAGTAAAATAAGCAAGCTTAAATTTGATTAGTTGTGTGTCTG 2847 CCTGAAACCATTTAGTAGAGCACTTTAATTCTGCATGGTTTTTA ETS2 ADXCRAD_AK023838_x_at GAGGTATCAGGGAACCGAGATCGCACCGCTGTACTCCAGCCTGGGCGACAGAACAAGACTTCG SEQ ID TCTCAAAAATATATCTATACAAGCACAAGGTT NO: 2869 FABP5 ADXCRPD.277.C1_x_at GTGTGTTGGATTAATTAGGATCATCCCTTTGGTTAATAAATAAATGTGTTTGTGCTAANNNNN SEQ ID NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCNNNNNNNNNNNNNNNNNNNNNNNNNNN NO: NNAATATGTTCGGGCCGCCTCGGGCCCTTCAAAAAACTTTTTCAAGAACCATTTCGTTTTGGC 1504 CCCCGCGGGCCCCAATAGGGTAAAGTGAAAACTTGGCCCATACCTTGTTTTCCCATAGGAAAA TCCCCTGGGCCATTGAACAAAGG FASN ADXCRAG_NM_004104_s_at TACTGTAACTGTCAGTGTACACGTCTGGACCCCGTTTCATTTTTACACCAATTTGGTAAAAAT SEQ ID GCTGCTCTCAGCCT NO: 1025 FASN ADXCRAD_BQ188744_s_at ATTTCCCCGATGTCCCCTGCGGGCGCGGGCAGCCACCCAAGCCTGCTGGCTGCGGCCCCCTCT SEQ ID CGGCCAGGCATTGGCTCAGCCCGCTGAGTGGGGGGTCGTGGGCCAGTCCCCGAGGAGCTGGGC NO: CCCTGCACAGGCACACAGGGCCCGGCCACACCCAGCGGCCCCCCGCACAGCCACCCGTGGGGT 2528 GCTGCCCTTATGCCCGGCGCCGGGCACCAACTCCATGTTTGGTGTTTG FBXL14 ADXCRPD.4724.C1_s_at GGAGGAATAGATGACTTTCTTTCTTTTGGTGGGGGTTGGGACTTGTGGCTTTAAAGAAATCAC SEQ ID TTCTGAGTAGGATGTATATTTTCGTTGGATTTTTGTTGTTATTTCTTTAGAACCCTCCACAGC NO: AACATGCAAGACCATGGAGTTAAAGAAACCCAGAGACCTTTATCAATTAATTGTACTGTTTGT 1696 GAAT FBXL14 ADXCRPD.10538.C2_at AATCTCATTGGATTACTCCTCCTTACATTACTGCGTTTGGATTTGTAGTCTTAACAAGGCAAT SEQ ID AAATGGAAGGGGAAAGAAGGAATCAATTCATGGTAACTAGAATGTAATGAGCACTTGCATTAA NO: GTCACAATTTAATTTGTATACTTTCGGAAATTCTTTCCTGGTTGTAAGCCTAAAGGGGCCTGC 2297 CTAG GCLC ADXCRAG_BC022487_s_at AGCCTGACTGCTCTCAGTGCAAAGACCCAGAACCCAGCCTTCCTTCACCTGAAACAGCTGCAG SEQ ID CGTGCACACACACTTCTTGTGCATATATCTCTGGTCTATTTATTTTCAAAACTAAGTATAATC NO: CAAATTGAATGCTGGAATCAGATTTTTCCATTCTGAATGTGTTTAAATAACATGGCCAAGGAT 948 AATTTCTTTCTGTTTTCTTGACATTTATAGGTAGTATAAGATATGTGACTTCCAAATAAAC GCLC ADXCRAD_CR738919_s_at AAAAATGGCGTTCTTCTCTTGTGGCCTGTTATTCTGATTGCTGCTGTATACAGTTTTGTCACT SEQ ID CTTTAGTTTTTAGTTAAGCATACTGATAGACTTTCCTCTAAAAGCCATTCACTCCAGATTTTA NO: CCTGGGGAATATTCTACATACTGCTTACTTTCTCTATAAAACTCATCAATAAATCATGAAAGG 1010 CACTGAGTTTTGTAAATCAGGACCCTAAATGTTTAATTGTAAATAAGTTTCAGATAATTATTA TAGCTTTGCGTTGAAGTTTGTTGT GCLC ADXCRPD.5046.C1_s_at ATAACTCTGTATTGTAGATTATGCAGATCTTTACAGGCATAAATATTTAAACTGTAATATGCT SEQ ID AACTTGAAGAGATTGCAATAAAGCTGCTTCAGCTAACCCTGTTTATGTTTAAATACTAGGGTT NO: TGTTCTATATTTTATACATGCATTTTGGATGATTAAAGAATGCCTGGTTTTCGTTTGCAATTT 1638 GCTTGTGTAAATCAGGTTGTAAAAAGGCAGATAAATTGAAATGTTTGTGGTATGAGGAA GCLC ADXCRPD.8360.C1_s_at GTAATTGTACAATACTTGCATTCCAGAGTTAAAATGTTTACTGTAAATTTTTGTTCTTTTAAA SEQ ID GACTACCTGGGACCTGATTTATTGAAATTTTTCTCTTTAAAAACATTTTCTCTCGTTAATTTT NO: CCTTTGTCATTTCCTTTGTTGTCTACATTAAATCAAATGAATCCATTGAAAGTGCTTCAAGGG 1851 TAATCTTGGGTTTCTAGCCCCTTATCTATGATGTTTCTTTTGCAA GCN1L1 ADXCRAG_U88837_s_at TGATACTGCCCACCATACAGAAGTCCTTACTGAGGAGTCCAGAGAATGTTATTGAAACTATTT SEQ ID CTAGTCTGCTGGCATCAGTGACGCTTGACCTCAGCCAGTATGCCATGGACATCGTGAAAGGAC NO: TGGCTGGTCACCTGAAATCCAACAGTCCCCGCCTGATGGATGAAGCTGTGCTGGCACTGCGGA 1077 ACCTGGCACGCCAGTGCAGTGACTCTTCGGCCATGGAGTCCCTGACCAAGCACCTATTTGCTA TCCTCGGAGGCTCGGAAGGAAAACTAACTGTTGTAGCCCAGAA GCN1L ADXCRAG_XM_0457920_at TAAAGGCTTTGATTTAATCTTGATATAAACAGATTTTTAAAAATCTCCACCCATTAAACATGA SEQ ID AGCTTCCTGCATCAGGAA NO: 1085 GCN1L1 ADXCRAD_BU599568_s_at TCTTCTCCTGTGCTTGAGCTCTGGTTTGAGAGCTGGCGCTACCAACCTTTTTCCTATATCCCG SEQ ID AGTGGGGCACAGACGGTGGATCTCTGCCCAGTGTGGTGTGTCTGGCTTGGCTTTTCAATATTG NO: TGAGGTCTGAATGGATCTGATCCCTGTCAGATGAAAATGATTCACAGCTCTGGCAGTTCCCAA 1086 GTCTGGGGAGGGGTATAGGTTTGAAAGGCTGTTTGAA GCN1L1 ADXCRPD.13574.C1_at AAGCCTTAGGTTGGTAATCCGGCTGAACTCGGCTTGACGGCCTGAGGCCC SEQ ID NO: 1664 GCN1L1 ADXCRPD.13574.C1_s_at GATGCCCTAAATGCCATCACTAAGAAGCTGGATGCTGGCAACCAGTTGGCACTCATTGAAGAG SEQ ID CTGCACAAGGAAATCCGGCTCATAGGGAACGAGAGCAAAGGCGAGCATGTGCCAGGATTCTGC NO: CTCCCGAAGAAGGGAGTGACCTCCATCCTTCCAGTGTTGCGGGAAGGAGTCCTGACTGGCAGC 1665 CCTGAGCAGAAGGAGGAGGCAGCCAAAGCCTTA GCN1L ADXCRAD_BQ890025_at TCCAGTTTAGCCATGGCTAGGGTCCTGGAACTATAATAAGCAAGGGTCCAGACTGGTGGGGTT SEQ ID TCCTCCTTTCTCCTGTGGCTTGGAACCTCTTGGGTTTGAAAAGCTGGGCGCCTACCNAAACCC NO: TTTTTTTCCCTATAATCCCCGGAATTGGGGGGCAACAGAACGGTTGGGGAATCTCCTG 2576 GCNT3 ADXCRIH.1160.C1_s_at GATCTTTTGCCTTGCAAATTGCTGCCTGGGTGAATGCTGCTTGTTCTCTCACCCCTAACCCTA SEQ ID GTAGTTCCTCCACTAACTTTCTCACTAAGTGAGAATGAGAACTGCTGTGATAGGGAGAGTGAA NO: GGAGGGATATGTGGTAGAGCACTTGATTTCAGTTGAATGCCTGCTGGTAGCTTTTCCATTCTG 1183 TGGAGCTGCCGTTCCTAATAATTCCAGGTTTGGTAGCGTGGA GCNT3 ADXCRPD.15673.C1_at GAAGGTCAGGACTTTGTGAACATATAAAACTGCAGATGGCTATTAGATATCCAAGTAGAGATG SEQ ID CTGAAGAGATGAATGTATATAGAAGTCTGAATTTGGGAGAGAGATCTGGATAGGAGATACTTA NO: CCTGGTGTTTAACAGCTTACAGATTGTGTAAAGTCATGAAACGGATAAGAACCTTAAAAGAGA 1778 GAAAAGGGAATAGAGGTTACCAAATGAATTGCAGTTTCCAAATTGCAGAG GCNT3 ADXCRSS.Hs#S1924358_at GGTGTGAACCGCTGTATCCAGCCTCTTTTTCAACTAACATCTTATCTGAGGTATAATATCCGT SEQ ID ATGCAAAAATACAAAAATTCCAAATATCTAACTCAAGAATTTTACAAAGTGAGCACACCTGTG NO: TAACTAGAACACTGGTCAAGAAAGAGAACATTCCCAGCAACCCAGAGTATCTCTTGTGTTCCT 2112 TTCCGATGGCTTTCCAAAAATAACCATTGTTCTCACTTCTAACATCACAGATTATTTTGCCTG TT GCNT3 ADXCRSS.Hs#S2978009_at TACTCCTCATGGATCATACCTCGCTCTCCTCAGATGTTTTAATATATCCTTGAGATGGGGTCT SEQ ID TGCTGTGTCACCCAGGCTGAAGTATACTGAGTGGTACAATCATTGCTCACTGCTGGCCTTGAA NO: CTCCTGAGATAGGAGGCGATCCCCCCATCTCAGCCTCCTAAAGTGCCGGGATTACAGACGTGA 2136 GCCATCGCATCCAGCCTGGAAGTATTTTGAAGGTTCAGTGTGAGGATTTGCTGACAGATTGAG CTGGAG GPX2 ADXCRIH.789.C1_s_at AGGAGCCTTAGGATGCAGCATGCCTTCAGGAGACACTGCTGGACCTCAGCATTCCCTTGATAT SEQ ID CAGTCCCCTTCACTGCAGAGCCTTGCCTTTCCCCTCTGCCTGTTTCCTTTTCCTCTCCCAACC NO: CTCTGGTTGGTGATTCAACTTGGGCTCCAAGACTTGGGTAAGCTCTGGGCCTTCACAGAATGA 1147 TGGCACCTTCCTAAACCCTCATGGGTGGTGTCTGAGAGGCGTGAAGGGCCTGGAGCCACTCTG CTAGAAGA GPX2 ADXCRPD.10475.C1_at AGGCTATACTCAACACACGTGCAATTGAAAGCAGGCGAGGCAAAACCAGGGCAGAGGAAAGGA SEQ ID AAGGGGTGTGTGTGTAGGTATGGATTTATGGGTAGGTAGGTCGGTAGGTTAGTTGAAGAGGAG NO: GTTCTAAGCAGTATAACCTAAGCCTCTTTTCTCTTTCTTCTGCTTCAAACACCTTAAGAACTG 1419 CTCAGGGTAGACTGGAGACAAAAGCAACAGCTCAGAAGTGCTAAATCTTGAAGAGCAGCCAAA GCATGGGCAACA GSR ADXCRAG_AY338490_at TCACTTGAGCTTGGGTGAGGTGAGGCTGCAGTGAGTCCTGATCATGCTGCTGCACTCAATCTT SEQ ID GGACAACA NO: 907 GSR ADXCRIH.3783.C1_s_at GACATCACTGATGATACGGCATGATAAGGTACTTAGAAGTTTTGATTCAATGATCAGCACCAA SEQ ID CTGCACGGAGGAGCTGGAGAACGCTGGCGTGGAGGTGCTGAAGTTCTCCCAGGTCAAGGAGGT NO: TAAAAAGACTTTGTCGGGCTTGGAAGTCAGCATGGTTACTGCAGTTCCCGGTAGGCTACCAGT 1148 CATGACCATGATTCCAGATGTTG GSR ADXCRPD.5551.C1_at AGACCGGCAATTTATGAGGAGTAGTAGGCGCACGGTACGCATCGCTCGTACCCATGTGACGCA SEQ ID AGGTCGACGCGGCCTNACTTACTAGGTGACTGACAGCGGGATGGGTGTGTCGTCACCCGGTCC NO: GCGCCCCACCACGCCCATGGTGATATGACGTTTCACTATAGTCCTAGACAGACGTACTCGTAT 1722 TTGCCCACGGGTCTCTGATGCTANACACCCACGCTGTTGCTCCANCGTTATTACCCATACCAC AAGAATGACGAGNCNCCCCTCTATTTTATTACACAGCGACGCCACG GSR ADXCRAD_BM978758_at AGCCTCACCTCACCCAAGCTCAAGTGATCCTCTCACCTCAGCCTCCCAAGTAGCTGAGATTAC SEQ ID AGATGCACATCACCACACTCGGGTAATTTTTTTTACTCTCTGTAGAGATGCAGTCTTGCTATG NO: CTGTGCATGCTGGCCTCAAACTTGTAGGCTCAAGTAA 2750 GTF2E1 ADXCRAG_BC005917_at AGACTGCTGCAGACGGGAAAACCACTCGCCATAACTACTACTTCATCAATTATCGTACTCTTG SEQ ID TTAATGTGGTAAAATATAAACTGGACCACATGAGCAGAAGAATTGAGACCGATGAGAGAGATT NO: CGACCAACCGGGCTTCCTTCAAATGTCCTGTCTGTAGTAGTACTTTCACAGACTTAGAAGCTA 920 ATCAGCTCTTTGATCCTATGACAGGTGAGGTTTATCCAGTTTGT GTF2E1 ADXCRAD_BG571275_at TGAGCCTTGTATGGAGTGATGTTTCATTTACCTGGGTTGTGTTAATGACTGAATGTTGACCAT SEQ ID AAATCTGTTTTATACTGACTGAAGTTTGTCATTTTTAAGTTCCTTGTAACCATCTTGCGCGCA NO: TATTCACCATTGAACTATTCTTTCCCAATATAAAAATACACGAACACACACACTTTTTCTGGC 2449 CCTCTGGCCCCTCTAAAAAATTTTTTTGACACCAATCGTTGGGCGGCGGCCCCGTGTGTTTGG AACAAGTGTGAACAAGGTTCCAAA HMGB1 ADXCRAG_AL110194_s_at AAATCTATAATTAATTGGGCCAACTTTTAAAATGAAGATGCTTTTTAAAACTAATGAACTAAG SEQ ID ATGTATAAATCTTAGTTTTTTTGTATTTTAAAGATAGGCATATGGCATATTGATTAACGAGTC NO: AAATTTCCTAACTTTGCTGTGCAAAGGTTGAGAGCTATTGCTGATTAGTTACCACAGTTCTGA 888 TGATCGTCCCATCACAGTGTTGTTAATGTTTGCTG HMGB1 ADXCRAG_U51677_x_at ATGATGAATAAGTTGGTTCTAGCGCAGTTTTTTTTTTCTTGTCTATAAAGCATTTAACCCCCC SEQ ID TGTACACAACTCACTCCTTTTAAAGAAAAAAATTGAAATGTAAGGCTGTGTAAGATTTGTTTT NO: TAAACTGTACAGTGTCTTTTTTTGTATAGTTAACACACTACCGAATGTGTCTTTAGATAGCCC 1068 TGTCCTGGTGGTATTTTCAATAGCCACTAACCTTGCCTG HMGB1 ADXCRIH.157.C4_s_at TTTAGTAGGTACGTCATGACAACTACCATTTTTTTAAGATGTTGAGAATGGGAACAGTTTTTT SEQ ID TAGGGTTTATTCTTGACCACAGATCTTAAGAAAAT NO: 1289 HMGB1 ADXCRAD_CN401906_s_at AACTCATTCATTAGTCATGTTTATCTGCTTAGGAGTTTAGGGAACAATTTGGCAATTTTGTGG SEQ ID TTTTCGAGATTATCGTTTTCTTAAAGTGCCAGTATTTTAAAATAGCGTTCTTGTAATTTTACA NO: CGCTTTTGTGATGGAGTGCTGTTTTGTTATATAATTTAGACTTGGATTCTTTCCATTTGCATT 2402 TGTTTATGTAATTTCAGGAGGAATACTGAACATCTGAGTCCTGGATGATACTAATAAA HMGB1 ADXCRAD_BX429991_at GTATGGTCTAACCTTTACCATAGGACTTTATTCTTTAAACTCCATTACATGTAAGGGCCGTTA SEQ ID TATTTTGCAGCCTCCACATTAAGAATACTTGGTATGCTTTCTCCAAAGCGGTGAGCTTATATA NO: CAAGACTGGCATATTAAAATTTTCCGCTACACTTACTCCAAGAAAGCTTTGGAATAGCAGTCT 2572 TAT HMGB1 ADXCRAD_DN601918_x_at GATGCTTCAGTCAACTTCTCAGAGTTTTCTAAGAAGTGCTCAGAGAGGTGGAAGACCATGTCT SEQ ID GCTAAAGAGAAAGGAAAATTTGAAGATATGGCAAAAGCGGACAAGGCCCGTTATGAAAGAGAA NO: ATGAAAACCTATATCCCTCCCAAAGGGGAGACAAAAAAGAAGTTCAAGGATCCCAATGCACCC 2603 AAGAGGCCTCCTTCGGCCTTCTTCCTCTTCTGCTCTGAGTATCGCCCAAAAATCAAAGGAGAA CATCCTGGCCTGTCCATTGGTGATGTTGC HMGB1 ADXCRAD_CX757597_at GAAAAGCGCCCATGTAACACAAACTGCCATTCAACAGGTATTTCCCTTACTACCTAAGGAATT SEQ ID GTACCATTGCTCAGAATTGTAGGATTTACTATGTTGAAACTACAGGAGAGCCGGGCGCATGGT NO: CACCCTGTATCCAGCCTTTGGAGGCANGCGGCAATCACAGTCAGAATGAACATCTGCTACTGT 2620 GAACCGCTCATAAATCAAAATACACTGTGCTGCCTGATCATATCGAGTAGCGAATGTGACGAG GATCAGACATGCTGCCACGGA HRSP12 ADXCRIH.2614.C1_s_at TACACCTGTGTGCACCTGTATTACTGAATATAGGAAAGAGATACCCATTACATAGTTACTCAG SEQ ID TAAACAAAAAGAGAAATACCAGGTAGGAAAGAAGAGTTACTATTCCTGAGAAATAATCAAGAA NO: CATATTTAATTTAAACTAATGATGTGAACTATTTAGTTTTGATGTCCGTTATGTGATTCTGCT 1098 TTTACTTGAGTAAAAT HSP90AB1 200064_at AATAGACTTGTGTCTTCACCTTGCTGCATTGTGACCAGCACCTACGGCTGGACAGCCAATATG SEQ ID GAGCGGATCATGAAAGCCCAGGCACTTCGGGACAACTCCACCATGGGCTATATGATGGCCAAA NO: AAGCACCTGGAGATCAACCCTGACCACCCCATTGTGGAGACGCTGCGGCAGAAGGCTGAGGCC 833 GACAAGAATGATAAGGCAGTTAAGGACCTGGTGGTGCTGCTGTTTGAAACCGCCCTGCTATCT TCTGGCTTTTCCCTTGAGGATCCCCAGACCCACTCCAACCGCATCTATCGCATGATCAAGCTA GGTCTAGGTATTGATGAAGATGAAGTGGCAGCAGAGGAACCCAATGCTGCAGTTCCTGATGAG ATCCCCCCTCTCGAGGGCGATGAGGATGCGTCTCGCATGGAAGAAGTCGATTAGGTTAGGAGT TCATAGTTGGAAAACTTGTGCCCTTGTATAGTGTCCC HSP90AB1 ADXCRIH.3279.C1_x_at CTTGTATAGTGTCCCCATGGGCTCCCACTGCAGCCTCGAGTGCCCCTGTCCCACCTGGCTCCC SEQ ID CCTGCTGGTGTCTAGTGTTTTTTTCCCTCTCCTGTCCTTGTGTTGAAGGCAGTAAACTAAGGG NO: TGTCAAGCCCCATTCCCTCTCTACTCTTGACAGCAGGATTGGATGTTGTGTATTGTGGTTTAT 1100 TTTATTTTCTTCATTTTGTTCTGAAATTAAAGTATGCAAAAATAAAGAATATGCCGTTT HSP90AB1 ADXCRAD_DN602116_s_at GAAAGTGGTTGTGATCACAAAGCACAACGATGATGAACAGTATGCTTGGGAGTCTTCTGCTGG SEQ ID AGGTTCCTTCACTGTGCGTGCTGACCATGGTGAGCCCATTGGCAGGGGTACCAAAGTGATCCT NO: CCATCTTAAAGAAGATCAGACAGAGTACCTAGAAGAGAGGCGGGTCAAAGAAGTAGT 2329 HSPD1 ADXCRAG_AJ250915_at TTTGTACATTCCTGATACTGGGTACAAGAGCCATGTACCAGTGTACTGCTTTCAACTTAAATC SEQ ID ACTGAGGCATTTTTACTACTATTCTGTTAAAATCAGGATTTTAGTGCTTGCCACCACCAGATG NO: AGAAGTTAAGCAGCCTTTCTGTGGAGAGTGAGAATAATTGTGTACAAAGTAGAGAAGTATCCA 881 ATTATGTGACAACCTTTGTGTAA HSPD1 ADXCRAD_BM313583_s_at AACAGCATGATTGGGTTAGGAATTTGCATAGGATGAGTTCAGTGGTGAGACTTTTGAAACTAC SEQ ID ACACATCTACCTTGTTTTAGTCCTATTTTCAAAATTTTGGCATTGTGAGATTTTATTTACTGT NO: GTGAACCTAAAGTTACTGTTTAAGTACATGCCACGCAACTCTGTGTTATTAAGAAGCACTGTC 2588 TCAGAAGCTGTGTGTAAATTTAATATTAAGGCACTAAAGACCAAGCATAGGTACATGCCTGTA HSPD1 ADXCRAD_AW674195_at TTTTTATTACACAAAGGTTGTCACATAATTGGATACTTCTCTACTTTGTACACAATTATTCTC SEQ ID ACTCTCCACAGAAAGGCTGCTTAACTTCTCATCTGGTGGTGGCAAGCACTAAAATCCTGATTT NO: TAACAGAATAGTAGT 2850 HSPD1 ADXCRAD_AW674195_x_at AATGTTTTACACACATGCCAGCCTGCCCTTCAACTGGCTTTCAATTTTCAGTATCTTCTAATC SEQ ID ATGGAAATGCTAACACAATTATTAACTTTAAACAAATTTTTATTACACAAAGGTTGTCACATA NO: ATTGGATACTTCTCTACTTTGTACACAATTATTCTCACTCTCCACAGAAAGGCTGCTTAACTT 2851 CTCATCTGGTGGTGGCAAGCACTAAAATCCTGATTTTAACAGAATAGTAGT HSPE1 ADXCRIHRC.2093.C1_s_at GGACTGCAGCTAAGTGTCCACTCCCCAAAGTCTTCCTATTCCTAACTCCATGACAGCTCCTCA SEQ ID GTAGAGCTTTCCTCCTCAGAAGCAACTAGAACAATGCAGTTAACATTATTTGGCCCCAACGGC NO: GTTTACTGTGTATTTTGGCTGAGATCTTTAGAAGCCCGAGGCCTAAACAATTAACTGAGGAAC 1380 ATCTAA HSPE1 ADXCRIH.2093.C1_at TTCTAGATGACAAGGTGTGTAAACTTAATAATTCTAAAAAGAAGTCAGATATTTGCAATTAGT SEQ ID TGTCTTAACTAATGGTTTTTTTCACTTGCAGGATTATTTCCTATTTAGAGATGGTGACATTCT NO: TGGAAAGTACGTAGACTGAAATAAGTCACTATTGAAATGGCATCAACATGATGCTGCCCATTC 2247 CACTGAAGTTCTGAAATCTTTCGTCATGTAAATAATTTCCATATTTCTCTTTTATAATAAACT AATGATAAGTAATCCTCGTGC HSPE1 ADXCRIH.2093.C1_s_at GAATATGGAGGCACCAAAGTAGTTCTAGATGACAAGGTGTGTAAACTTAATAATTCTAAAAAG SEQ ID AAGTCAGATATTTGCAATTAGTTGTCTTAACTAATGGTTTTTTTCACTTGCAGGATTATTTCC NO: TATTTAGAGATGGTGACATTCTTGGAAAGTACGTAGACTGAAATAAGTCACTATTGAAATGGC 2248 ATCAACATGATGCTGCCCATTCCACTGAAGTTCTGAAATCTTTCGTCATGTAAATAATTTCC HSPE1 ADXCRIH.2093.C2_at TTCTAGATGACAAGGATTATTTCCTATTTAGAGATGGTGACATTCTTGGAAAGTACGTAGACT SEQ ID GAAATAAGTCACTATTGAAATGGCATCAACATGATGCTGCCCATTCCACTGAAGTTCTGAAAT NO: CTTTCGTCATGTAAATAATTTCCATATTTCTCTTTTATAATAAACTAATGATAACTAATGACA 2249 TCCAGTGTCTCCAAAATTGTTTCCTTGTACTGATATAAACACTTCCAAATAAA HSPE1 ADXCRI H.2093.C2_x_at TTCTAGATGACAAGGATTATTTCCTATTTAGAGATGGTGACATTCTTGGAAAGTACGTAGACT SEQ ID GAAATAAGTCACTATTGAAATGGCATCAACATGATGCTGCCCATTCCACTGAAGTTCTGAAAT NO: CTTTCGTCATGTAAATAATTTCCATATTTCTCTTTTATAATAAACTAATGATAACTAATGACA 2250 TCCAGTGTCTCCAAAATTGTTTCCTTGTACTGATATAAACACTTCCAAATA IL27RA ADXCRAD_BG756941_at GCAAGACCCTCAGTACAAAATAAACGTCAGAAACAAAAACAATTAGCTTGGGGCATTATGGCA SEQ ID CACACCTGTTATCCGAGCCACTTGGAAGCTGAGGGGGAGATCGGTTGAGCCAGGAGTTCGAAG NO: TGAGGACTCTGATTGCACATGGATCCAGGTGCGTACCAATGGACTTTTTCAAATA 2631 IL27RA ADXCRAD_NM_004843_at AACACTGCATTTGGGCACCATCTCAGCTCCCTTGCATCCAGGTGCAGCATGGACTGAGTTCTT SEQ ID GACAACAGAATGTGGTCAGAAGTGACATATGCCAACACGGGGTCTGGGTGGGGGCTCCCCCAC NO: ATCCTTTCCTTGCCTATGAGCTGGAACATAACACATGCCTATGATCCAGCTTTGGTCATACCC 2770 AAGGGGAAGGTGGAGCAAGAAATGAAAAGGAACCTGAATCCCTGAATGACTGCATGGATAGAA CCACT INSIG1 ADXCRIH.1510.C1_s_at GAATGACCCCCTTATATATTTTCTGAAAATGAAAACAGTTACATGAAAAAAATTTCCAATGAA SEQ ID GATGTCAGCATTTTATGAAAAACCAGAAGTTATTAGATGAAAGCAGCGAGTGAATCTTTAAAC NO: AGACTTGATCACGCACACACAATAAGTCTTTCTCTCC 1196 INSIG1 ADXCRAD_BU191559_at AATCTATTTAGATCGGGCTGACTGTACAAATGACTCCTGGAAAAAACTCTTCACCTAGTCTAG SEQ ID AATAGGGAGGTGGAGAATGATGACTTACCCTGAAGTCTTCCCTTGACTGCCCGCACTGGCGCC NO: TGTCTGTGCCCTGGAGCATTCTGCCCAGGCTACGTGGGTTCAGGCAGGTGGCAGCTTCCCAAG 2371 TATTCGATTTCATTCATGTGATTA INSIG1 ADXCRAD_BU570382_at GATTTTTTTGCCAATAGTTTATAGAAAATATATGAACCAAAGTGATTTGAGTTTGTAAAAATG SEQ ID TAAAATAGTATGAACAAAATTTGCACTCTACCAGATTTGAACATCTAGTGAGGTTCACATTCA NO: TACTAAGTTTTCAACATTGTGT 2372 INSIG1 ADXCRAD_BU570382_x_at GATTTTTTTGCCAATAGTTTATAGAAAATATATGAACCAAAGTGATTTGAGTTTGTAAAAATG SEQ ID TAAAATAGTATGAACAAAATTTGCACTCTACCAGATTTGAACATCTAGTGAGGTTCACATTCA NO: TACTAAGTTTTCAACATTGTGTTCTTTTTGCATTCATTTTTTA 2373 INSIG1 ADXCRAD_AL541939_s_at TTTTAAATTCTGTGAAAGTGGCTTGATTAAAAG SEQ ID NO: 2611 KBTBD11 ADXCRPD.18308.C1_at AGGCAGTCTCAGCAATGCCTCTGCCCTCCCTGCAGCAGTCCCAAAATGAACAGCCACACCTTG SEQ ID GAGGGTGTGGCTTTTCTGTTTCATGCGGTGCAAACCCTAGCGGCTCCACACCCCAGGGACTGG NO: CCCCCAAAAAGCAAAAACACTGCTCATGGCTTGGCAGGTCCTCTAGTATGTATTTTTATGTGA 1420 TATCACTATTCAGAACTGTGGTGTATACTATTCTATAAATTTCCACTATAGGTTGGCCGGACA TCCTTTAATGCTGGGTATTAATTCCTCTTATTCT KBTBD11 ADXCRPDRC.18308.C1_at GGTTCATGTGAGATGCAGAGGCAATGAGCTTGAGCCTTCCTACCTTTACTTCCGGCTGGATAC SEQ ID TTGCTCTGGGGAACAATCCCATCAATACCGCAGACGGCTTTGCCGGCCGCCTTCGCCAAAGCC NO: TGGGATTCGGAAACATACGGGGAAACGGGGCGCGGAATCCGAGGAGGGCCACGACAGCGACCA 1927 GGGAGAAAAACGGCAGGTGCGGGAAGAACCTGGGCCACACAACAAAAACACGGAAGTGAGAAC ACCTGGCCACACGAAGGAAGACATGAA KBTBD11 ADXCRAD_NM_014867_at CTTCAGACACGCCAAGTGGATGGATTTGGATTGAACGCATATGAAACAGGAGACGGGTTCTCA SEQ ID TGTGAGATCAAAGCTCCTCCAAAGCCTGTTCAAGCTCTAAGCGATTCTCAAATGTTACCATTT NO: ATTAAAGGTAAACTACACCTGTTGAAGGCCAAGTTCAGGGCAGCTGTTGTGATCTGTGTAGTT 2772 AATGTATTTATTAATGCTTGACTTTTAAAATCCTGGGCATAAATAGTGCAGAGCCTCGTATGT TTGTCAGTTCATGCCGAGATG LGALS4 ADXCRIH.255.C1_at AGAAGAAGATCACCCACAACCCATTTGGTCCCGGACAGTTCTTTGATCTGTCCATTCGCTGTG SEQ ID GCTTGGATCGCTTCAAGGTTTACGCCAATGGCCAGCACCTCTTTGACTTTGCCCATCGCCTCT NO: CGGCCTTCCAGAGGGTGGACACATTGGAAATCCAGGGTGATGTCACCTTGTCCTATGTCCAGA 1258 TCTAATCTATTCCTGGGGCCATAACTCATGGGAAAACAGAATTATCCCCTAGGACTCCTTT MRPL16 ADXCRIH.2001.C1_s_at ACATGCTGGGCATACGGAAAGTACTGAGCCCATATGACTTGACCCACAAGGGGAAATACTGGG SEQ ID GCAAGTTCTACATGCCCAAACGTGTGTAGTGAGTGTAGGAGATAACTGTATATAGGCTACTGA NO: AAGAAGGATTCTGCATTTCTATTCCCCTCAGCCTACCCACTGAAGTCTTTGGGTAGCTCTTAA 1144 GCCATAACTAAGGAGCAGCATTTGAGTAGATTTCTGAAA MRPS2 ADXCRAD_AL583494_s_at TTGGCTGCAGTTAGGACCTCAGTGGCTGGTATGGCCGAGCTGCTAGAAGATGCTGCTGTCCCT SEQ ID GTGATCCCAGCAGCCCTCCCTTCACCGTGACCCCTGACCTTTGTCAGGAAGGTGCAGTTTTTC NO: TTCTCAATCTAAATGCCTTTCAGGTGGGCCGCTTCCTTGGCTACCTGGTTCCAGGGGGCTGTT 839 TTGTAATGAGATGCTGCTGGCAGGCCACTCAGAGGCTCCCAGCTGGGTTGGTGGGACAGCCAG GCCAGATGACCTGATTCCAGCAAAAATAA MRPS35 ADXCRIH.1462.C1_at AAACTTGTAGGAGAGCGATACTGCAAGACCACAGATGTGCTTACCATCAAAACAGATAGGTGC SEQ ID CCTTTAAGGAGGCAGAATTACGATTATGCAGTGTATCTACTAACAGTGTTATACCATGAGTCT NO: TGGAATACTGAAGAATGGGAAAAAAGTAAGACTGAAGCAGACATGGAAGAGTATATATGGGAA 1155 AATAGCTCATCAGAAAGAAATATCCTGGAAACGCTCTCCAGATGAAAGCTG MRPS35 ADXCRIH.2579.C1_at AATGGGTTCTGGGCCTGCCTTCCCAGGTAACCAAAACCATTATTCAAAAGCAACTACTGAAAT SEQ ID GCCAGCTTGTGGGGAAAGAAATGGGAAAGGTGATAAAATCACAATTAAATGCATGTATATACA NO: TGAATACCAAAGCTATTATGTAGAAATAAAATCAAAACACTTTAGACCAAGAAGAAATCAGAG 1213 ACCTCCTAGTCTATTGCCCCCAGTGTAAAAATTAAAAAACTCTGGAGTAATCATTGCCATTAA GCATTAGTATG MRPS35 ADXCRIH.2579.C1_x_at AAGGAAATGGGTTCTGGGCCTGCCTTCCCAGGTAACCAAAACCATTATTCAAAAGCAACTACT SEQ ID GAAATGCCAGCTTGTGGGGAAAGAAATGGGAAAGGTGATAAAATCACAATTAAATGCATGTAT NO: ATACATGAATACCAAAGCTATTATGTAGAAATAAAATCAAAACACTTTAGACCAAGAAGAAAT 1214 CAGAGACCTCCTAGTCTATTGCCCCCAGTGTAAAAATTAAAAAACTCTGGAGTAATCATTGCC ATTAAGGATTAGTATG MRPS35 ADXCRIHRC.2579.C1_at GGCTCATTTTGCCAGGGCCAAGCTACCAGAAAAGTAGAAGTGGAGATTACCTGGTATGTATCT SEQ ID CTCTGGGTGCCCCAGTTAGAGCTGCCACAGCTCAGGAAAAAGATGAGGCATAACGACCTTGAA NO: TGTAATTGGAGTAAGTGACAAAATAAGAACTACCCTGGGAAACCCTGCATTCAATGTAGCTGT 1324 CAATTCAGTATTTTTAAGTACACCTGTCAGCTGTTTCTTACCACTTCGATGGTTGTGATTA MTHFD2 ADXCRI H.873.C1_s_at GCTGCAAAAAAGGTGCTGAGGCTTGAAGAGCGAGAAGTGCTGAAGTCTAAAGAGCTTGGGGGT SEQ ID AGCCACTAATTAACTACTGTGTCTTCTGTGTCACAAACAGCACTCCAGGCCAGCTCAAGAAGC NO: AAAGCAGGCCAATAGAAATGCAATATTTTTAATTTATTCTACTGAAATGGTTTAAATGATGCC 1189 TTGTATTTATTGAAAGCTTAAATGGGTGGGTGTTTCTGCACATACCTTCTGCAGTACCTCACC AGGGAGCAT MUC13 ADXCRIH.333.C1_s_at GGGTGTAGGTTTCTGAGGTGTGCCATTGGGGCCTCAGCCTTCTCTGGTGACAGAGGCTCAGCT SEQ ID GTGGCCACCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAATGGGGGCAACCACATCCA NO: GTACAAGCTTTTACAAATGTTATTAGTGTCCTTTTTTATTTCTAATGCCTTGTCCTCTTAAAA 1126 GTTATTTTATTTGTTATTATTATTTGTTCTTGACTGTTAATTGTGAATGGTAATGCAATAAAG TGCC MUC13 ADXCRIH.2577.C1_s_at AAGATCTGAAATGCGTGCTGATGACAAGTTTGTTAATGTAACAATAGTAACAATTTTGGCAGA SEQ ID AACCACAAGTGACAATGAGAAGACTGTGACTGAGAAAATTAATAAAGCAATTAGAAGTAGCTC NO: AAGCAACTTTCTAAACTATGATTTGACCCTTCGGTGTGATTATTATGGCTGTAACCAGACTGC 1212 GGATGACTGCCTCAATGGTTTAGCATGCGATTGCAAATCTGACCTGCAAAGGCCTAACCCACA GAGCCCTTTCTGCGTTGCTTCC MYC ADXCRIH.2640.C1_s_at TGATCAAATGCAACCTCACAACCTTGGCTGAGTCTTGAGACTGAAAGATTTAGCCATAATGTA SEQ ID AACTGCCTCAAATTGGACTTTGG NO: 1105 MYC ADXCRPD.8111.C1_at CAGTGTCCGTCTCCGGCTGTCAGAAATGCGGTGAGCCGAAATTTAAATGCCCTCCCGGAGACG SEQ ID GGGACAAGTCAGCGGCTGCGGAGCGATCTGGCTCACACAGGCGATATGCGGTCCCTACTCCAA NO: GGAGCTCAGGATGCAAGGGGCTTTCTGCCCACCGCAAAGCAACCCCCAGCCCCCCAAAACCCA 1806 GAGAGCAATTAACACAATAAAGCAGGAATGTCCGACCGGCCGGGAGTCAGCGTGAATATATTC ATAAGGCAGAAATCTCGAAAGGGTAGTCTT MYC ADXCRSS.Hs#S854806_at GGGAGGAGACTCAGCCGGGCAGCCGAGCACTCTAGCTCTAGGATGTAAACAGAGTAAGAGAGC SEQ ID CGCATGAATTAACTACGCGCGCCTACCATTTTCTTTTGCTCCCTCTCAAACCCTCTCCCTTTC NO: TCTGCTGCTCCTCCGTAGCAGTACTGTTTGACAAACCGCATCCTTGTCCTGTGAGTATAAATC 2226 ATCGCAGGCGGAACAGCTG MYC ADXCRAD_CA454569_at TAAATATTGGGCCATTAAATGGTAAATAAACTTTTAATAAAACCGTTTTATTAGCAAGTTACA SEQ ID CCAGAAATTTCAATCCCCTAGGTATATATAGTACCCTCAAGTATTTATTA NO: 2390 NDUFAB1 ADXCRIH.1103.C1_s_at TTGGGTTTGAAATTCCTGATATAGATGCTGAAAAGTTAATGTGTCCACAAGAAATTGTAGATT SEQ ID ACATTGCAGATAAGAAGGATGTATATGAATAAAGTATCAGACCCTTTGGCTTTGCTGAGAGAG NO: GACTCAGATGATAGTGACGAATGTCTGGCAGTGAGGACACATTTTGGCATTCTTGCTGACTCT 1172 GACAGAGTGATTCTGATGGACTTGTATTTAA NUP37 ADXCRIH.1894.C1_s_at AAATTCATCATTTAGGACACCCTCAGCCCATCCTCATGGGTTCTGTAGCCGTTGGATCTGGAC SEQ ID TGTCCTGGCATCGAACTCTCCCTCTGTGTGTAATTGGAGGAGACCACAAGCTGTTGTTTTGG NO: GTGACTGAAGTATAAAGTGTTTTCTGTACCTTAGATTCACAAACTTTGTATTTTTAGTACATA 1171 TTTTGAAGAATTTCTATAGTACATATTTTGAAGAATTTTTATATCAAATATACCGTATACTTT AGAAAATGTCTCAGTTGCTTTTATTA NUP37 ADXCRSS.Hs#S1923985_at AAGCAACAAGTAAACACACCTATGAAAGCAACTTGTTTGAGCTGTCTCAACTTCTCTGCAGCT SEQ ID GTTCTGGCTGTATCTGTATTCTAGTACTTCTTTGAACTCTAGAGAAAAGTTTGTTCATCAAAA NO: CCTCATGAAGTTTAAAGGTAGTCTATTGCCTTTTGTCCTTTTTCAAAAATCTTATTTCTTTAT 2111 TTAAATTGACAGGTAAAAATTGTATTTTTATGATGTACAACATGATGTTTTGATATATGAATA CATTGTGGAATGGCCAAACCAAGCAACC PDCD4 ADXCRAG_NM_014456_s_at CATTACTGGTGGGATCTGGTCACACAAGATAGCATTAAACGTGACATGGCACATAAAATTGGT SEQ ID TAAAAAATTTTGTTTTTTAATTACGTAATGTAAAAGCCCAACAAACACTTTATGCAAGATTGG NO: 1042 AATGTATCTTCAA PDCD4 ADXCRPD.13022.C1_s_at GAAATTCCGGACATTAATCTGGATGTCCCACATTCATACTCTGTGCTGGAGCGGTTTGTAGAA SEQ ID NO: GAATGTTTTCAGGCTGGATAATTTCCTTACAACTCAGAGATCTTTGTCCTTCAAG 1567 PDCD4 ADXCRPD.5572.C1_s_at TTCCAGGGAACATACTGATTGGTCTTAAAAGACTAGACAGTTAAGTAAAAGGTGGCTGGAACA SEQ ID TCTATTTTTCTACAAAACTGGAAAAATGAACCTGGTTCTAGAAGAATGTACACCAAAATAAAA NO: CATGTGAAGCAGTATTGATTCTTTATTGGGAGTACATTTTTTAGGTCTCTTAAACTTTAATTT 1724 CACACA PDCD4 ADXCRSS.Hs#S1435288_at TGTTCCCACGGAGGTTTCTGCTTGTTCCCAGTAAGTTGTGATTCTCTGTATCCACGTGTCTTT SEQ ID CTCCAATTTGGGGGGCTTCAGTTTGCTCTGTGACCTCCATTCTCTGATGGATCTAAGAAGAGT NO: TGTTGATTTTCAGTTTGTTTAGCTATTTGTTAGGACAGAGTGACAACTTTCAAGCTCCTTACA 2076 TGCTGCATCAGAAACCAGAA PDCD4 ADXCRAD_BE544684_at ATTTACTATGTATGTTTCACTTACAATTTGTAGGGAAAAAAAGTCTTCAAGGGAACACTAAGA SEQ ID TTAAATGACCTAGCGTTCAAATATGCTTCCTTATGAGATTCACAATTTACCTGTGTGAAATTA NO: ACGTTCTAAGAGACCTAAAAATGTTCTCCCCAATAAGAACTCATACT 1567 PDCD4 ADXCRAD_BE544684_x_at AAGTGATACCTGCATTTTTTCCCCAGGTAATCTTAATTTACTATGTATGTTTCACTTACAATT SEQ ID TGTAGGGAAAAAAAGTCTTCAAGGGAACACTAAGATTAAATGACCTAGCGTTCAAATATGCTT NO: CCTTATGAGATTCACAATTTACCTGTGTGAAATTAACGTTCTAAGAGACCTAAAAATGTTCTC 2548 CCCAATAAGAACTCATACT PDCD4 ADXCRAD_BM550622_at TCTGACCTAGAGCTTTATTTAAGTTTTAGAAATATGTAATACCTTTCATCATTCCATCATCC SEQ ID CTAAATTCTGNTACCCAAATAATGGCTAATGTTACAAAAAGTTATACTCCCAGAGACCCAA NO: AGCTTGACATTTACCTATTGTATTGAGAAATTATTCCCAATACCAATAAAGGAATGGTCCTA 2663 TTTTTTAACCCCTCTTTTAACTAGCCTAATACCTCCCGCAAGGCCCTCAACGTCCT GGGGCTA PDCD4 ADXCRAD_BM550622_x_at AATGCAGGTATCACTTTTACTCCATTGTTATCTGACCTAGAGCTTTATTTAAGTTTTAGAAAT SEQ ID ATGTAATACCTTTCATCATTCCATCATCCCTAAATTCTGNTACCCAAATAATGGCTAATGTTA NO: CAAAAAGTTATACTCCCAGAGACCCAAAGCTTGACATTTACCTATTGTATTGAGAAATTATTC 2664 CCAATACCAATAAAGGAATGGTCCTATTTTTTAACCCCTCTTTTAACTAGCCTAATACCTCCC GCAAGG PDCD4 ADXCRAD_BC043171_at CATTGGTAGGGAACTATCCAGTATTTATATTCCTATGTATGTATATCAGATTAATTTTGAGGC SEQ ID TTGGTATTCCTAAAAGATTTGGATGTGTGTATTTCTTTAACTTGACGTAAACATGTATCACAA NO: ACATATCTTTTAATTCCAATTAAAGGGGTGCTTTGGCACATGCTG 2781 PDCD4 ADXCRAD_BC043171_x_at CATTGGTAGGGAACTATCCAGTATTTATATTCCTATGTATGTATATCAGATTAATTTTGAGGC SEQ ID TTGGTATTCCTAAAAGATTTGGATGTGTGTATTTCTTTAACTTGACGTAAACATGTATCACAA NO: ACATATCTTTTAATTCCAATTAAAGGGGTGCTTTGGCACATGCTGAAATCTGGGATTTT 2782 PDSS1 ADXCRAD_BM824056_s_at AACTTCGACCATCCCCAGAAAGAGATGCCCTCATTCAGCTTTCAGAAATTGTACTCACAAGAG SEQ ID ATAAATGACAACTCTTTCTGTTCTTTCTGGCAGCTATCTTACCAGACTGTGCCTAAAGAATTT NO: TGTGGAATACACTTTGTTTGCTTCATGTGCAGATAACCAAAAATCATTTTAAAAGATATCAAA 862 CTTATTGATGGGCAAT PDSS1 ADXCRPDRC.11127.C1_at GCACACCATCACTCTGTAGTACATACTGTCGAGCTCTGTCTACATCTCCAGGCAAACTGAACC SEQ ID GTCGCATGATCATAGCATTCATTTCTGGGAACTGCTGACAGGCAAACAGGACAGGACCAGTGG NO: CTAACCCGAGCTTCAGATCAGCTGATGTTGGTTTGCCCATCTGGTCAGAACACGAGGTGAAGT 2058 CCAATACATCATCTATTAGCTGAAAAGCTATTCCTACATTTTTTCCGTACTGATAGGCGATCC CA PGD ADXCRAD_CX873763_s_at ACAGACCAGGACATTCCATGTGCCTCATGGCACTGCCACCTGGCCCCTTGCCCTATTTTCTGT SEQ ID TCAGTTTTTTAAAAGTGTTGTAAGAGACTCCTGAGGAAGACACACAGTTTATTTGTAAAGTAG NO: CTCTGTGAGAGCCACCATGCCCTCTGCCCTTGCCTCTTGGGACTGACCAGGAGCTGCTCATGT 912 GCGTGAGAGTGGGAACCATCTCCTTGCGGCAGTGGCTTCCGCGTGCCCCGTGTGCTGGTGCGG TTCCC PMM2 ADXCRPD.16616.C1_at SEQ ID CTGGCCAAGTGGGAGCAGACCCTAGGGAGTTTGCACCTCGGCTGGGCCGGATTCGGACCGGCT NO: CTGTGTTCACTACACTCAGAATAGCCTGGCTGCTTCTCTGTCTCCGAGACCGGAGGTAGTGGG 1826 AACCAACAGCTGGGCTGGAGAGTTGGTGCTGGCAAAACAGTCCTTGCCCTGGGGCCGGTTCTT ACCCAGGTCCAGAGAAACCAACGCGGGATGTCAGACTTCACCAAAAGGACTTTCTGGTTGCCC CTG PMM2 ADXCRAD_BE390153_at SEQ ID TGGGCACTTGCCGACCTGAGTCTGGGGCCAGGGAGCCCAGGCTGCCCTGCACTCCTGCCTCCC NO: AGCCCACAGCCAGGTGCTTTCATCACAGCTAAACCTGGTTCCCTCCAAACCTCCCAGCCACTC 2408 GGGCTTGTAACTGTCTGAGCCCCGGATCCGGTGGGGTGAAAGCAGCCAGCTCATCCCAGTGAC TCACAGGACACAGCCATCCAGCGGCATCTTTCCTTGTCGAATGATACTGTAATGACCTTCCAA AGTGAAGAGTAGCAC PPRC1 ADXCRPD.9220.C1_at CAGGTATTGAAACAAGTTAACTTGCATTCCTATGTAAGATAGGAGGGGCTGAGGGGATCCCCA SEQ ID NO: GTGTTTGGAACATAAGTCACTATGCAGACTAATAAACATCAACTAGAG 1398 PPRC1 ADXCRPD.9220.C1_x_at TCCCTGCTATCCTTTTTCTCCTTTGGAGGTGCNCCAACCTCCTCCACCCCCTTCCCCTACTCT SEQ ID AGGGGAGAGAGCTGCTAGTGAGATGACTGTTTTATAAAGAAATGGAAAAAAGTGAAATAAAAA NO: ATATGTTGAATCAGATTTTTTAAAAGGGGTATTTGTTTTTTTATAACAGGTATTGAAACAAGT 1399 TAACTTGCATTCCTATGTAAGATAGGAGGGGCTGAGGGGATCCCCAGTGTTTGGAACATAAGT CACTATGCAGACTAATAAACATCAACTAGAG PPRC1 ADXCRPD.16668.C1_at AGGGCTTCACTGCAGAGCTGTCTTCTTGGCTGGGGCTGGTGGGATGACAAGACAAGGGATGTC SEQ ID TGCCAGCCCTGTGGGAGTCTCTGGAAGGCTAGGCCACTTCCCAGTTGGGGGCTGTGGACTTCT NO: CTCTTCTGTTTCTGCTTGGCGTTGCTGCCTTCGTCGCCGGTACTCAGATAAGCTGAGAGGCCG 1832 AGGTCTGGCTTCATGGGTTGTAGCACTGGTACCACTTTCAATTTTCA PPRC1 ADXCRPDRC.16668.C1_at SEQ ID GAAGAGAGAAGTCCACAGCCCCCAACTGGGAAGTGGCCTAGCCTTCCAGAGACTCCCACAGGG NO: CTGGCAGACATCCCTTGTCTTGTCATCCCACCAGCCCCAGCCAAGAAGACAGCTCTGCAGTGA 2033 AGCCCTGAAACACCCCTTGAGATTTGCCTTGTGCCTATAGGTCCCAGCCCTGCTTCTCCTAGT CCTGAGCCACCTGTAAGCAAACCTGTGCCTCATCTCCCACTGAGCAGGTGCCATCCCAGAAGA TGCCACTGTTGGCGAGACCTT PRIM1 ADXCRPD.724.C1_at CCGTGAATTGGATGCCATTTCCACTAATGAAGAGGAAAAAGAGGAGAATGAAGCTGAATCTGA SEQ ID TGTCAAACATAGAACCAGAGATTATAAGAAGACCAGTCTAGCACCTTATGTGAAAGTTTTTGA NO: ACATTTTCTTGAAAATCTGGATAAATCCCGAAAAGGAGAACTTCTTAAGAAGAGTGATTTACA 2266 AAAAGATTTCTGAAGACAGAGCTCCTCAAACCATTGTGGATATCTTCTGCCTTCAACCACAGA TCAAATACTTCAAGAGCCATTTAATAAA PRIM1 ADXCRPD.724.C2_at GCCATTGCAACTGGCCGTATTAAGTCCTTTGTATCCTCACTGTTCCATACTAGCTCAGCCTAT SEQ ID GATGTGGACTTCAGCAAATGTGTAAGCAAATCTTTGTGCATGATGTGTGTTAAATAGAAGCAT NO: TAGGCAAAAAAGAATGTAAAAGTAAATGGGCTTTGTTTTGTTTCCTTTGCTGTTCTTCCATAT 2267 ATTATC PRR13 ADXCRIH.1445.C1_at TCCACTTATAATACTTGTGATTGGGGAGGTTTGTGGAAATTCAATTATGATGAAAAACCTATC SEQ ID TTTTTTGTAATGTTGGCATACTTGGGGAATTTAGTGGCAAATACATTCCCCAGCAGGCCTTTT NO: GTTGGTTGCACTAACTGCAAGGTTGCTGGGAAGTAGAGTCCATTTGGTTGATGAGCTTTGACT 1285 GCGGTTTTGGAACCTTACCTCTCCTCCTTAGCCCAATATGCTGTCTTGGGTCCT PTGES2 ADXCRIH.498.C1_s_at ACAGGACAGCAGGACGGTTTGTTTTCAGTGGA SEQ ID NO: 1170 RNPS1 200060_s_at CAGGGAAAAGTGAGGCTCTTGGGGGTGGTTTGACCCTGCTTACCTGGGAGCACACTTTTCCCT SEQ ID TCCCCGATGACCTGGGATGGTGGCCAGGCCGTGCCCTTGCTGTTGCTGGGCAGTGTCCTTTTG NO: GAAAGGGAGCTGCCCCAGGCTTTAGTGCAGCTGCCAACCCTGTTAGGCCTGGCCTCTCGAGGC 832 CTCTTCTGATCTCAAGGGTCACACCCCCTCAAAGATCCTCTCACCCATGGTAGTTGCTGCTCG TGGTTCTGTCTGTCCGTGCACCGATGCACACACCGCACCCCACCACTGTACTCTGAAATTGGC GAGTGAGTGGAGAGCCAGCTCTGCGGAGTCATCACGCAGCCATGGTTGTGCCTGCCGTTCATG GTGGTCTTTCAGGTTATCTTGGCAACATGTACATTGCTTTTATTTTTTTTCTTTTTTGCTTTC ATTGTACAGTCAGTACTATAAAATTTCTCTTTTGAGTTTTATACCTTTGTAGCATTTTAGATG ACATTGTGTTTGTACTTTGTTG RNPS1 ADXCRPD.500.C1_at ATGCATAGATATACACACCACGCCCCCACCGCGATGTTAACGACACCGCGAGATAATACTATT SEQ ID CCCCCCACACTGCGTCTCTGTTCTGTTTCTNAGCACACCTCTCACCTCTCCTCTTATCTCTGT NO: GGCGGTCGAGAACATTGCACTCACCCCACTATTTATCTCTATTCTTTCTCTATTACTGACCAA 1561 CATATCCTCTGTGCGCACCCTCGCGCGGAAACAACAACATCGTGTACACACCACAAGAAGTAA GCACATGATTGCTAGCCTGGGACACCGCGCCCTCATAATATATA RNPS1 ADXCRAD_CX785467_at GATCGGAATGCAAATCTAGTTCTGGGTTCACTGCCTTCTCACTT SEQ ID NO: 2688 RNPS1 ADXCRAD_CX785467_x_at GATCGGAATGCAAATCTAGTTCTGGGTTCACTGCCTTCTCACTTGTCCCCTCGCCCCTAGTAA SEQ ID NO: CTTTCTGTTCCTCACCA 2689 RNPS1 ADXCRAD_NM_006711_at AATAAACCCAAGATCATCTGAGATGAATATTAATTTTATTCTCATTTTATAGATGAGGAAATG SEQ ID GGAGTTTTAAAGACATTCAATAACTTTGGCCAAGGTCATTCAGCTATTAAATTTTAAGACCAT NO: AAACCAATTGGATTCCTGGAGGAATTC 2859 RPL13 ADXCRIH.350.C2_s_at GAATCAGTCGGCAGTCATGCTGGGTCTCCACGTGGTG SEQ ID NO: 1273 RPL13 ADXCRAD_BM907731_at TTTACACCACCCTCGTGGAATTGGCGAAAAAAACTGCCCGAGCTTGTGGGAAACTTTTTGTGG SEQ ID GAGAGGAACCCCTTACTTTTCGGGGGGGGGGCGCACAAATTTGGTGACCAACCTCCGCCCCCC NO: ACAGAATTTCGAGGCCCCCCGAGGGGACCAAAATAAACACTCTTCTCAGCCGACACATTGCGG 2637 CTAAAACAAACGCACCGACAAAATACCTTTCGCGCGCGGTTGAGAACCATTTTC RPL13 ADXCRAD_AI554467_at AGACAGGTTGTTAAACCCACATGCACCAAAGGGCAAGGGAACAACCAAGCGTCAGGAGAACCC SEQ ID GGAGGACCTCCCGGGGATTGGGGGTCAGGTTCGCTGCCATAAGTACTGCTGAAAAGCAACCCT NO: GAGTCAATCACCTTCCCTG 2882 RPL13 ADXCRAD_AI554467_x_at GCTTTCTCCTTCTTATAGACCTAGAAGAGAAAGACAGGTTGTTAAACCCACATGCACCAAAGG SEQ ID GCAAGGGAACAACCAAGCGTCAGGAGAACCCGGAGGACCTCCCGGGGATTGGGGGTCAGGTTC NO: GCTGCCATAAGTACTGCTGAAAAGCAACCCTGAGTCAATCACCTTCCCTGGGATTTA 2883 RPL13A ADXCRIH.613.C1_at SEQ ID AGCGGCCTGGCCTCGCTTGGTTTTGTGGGGCAGCATACCTCGCACGGTCCGCCAGAAGATGCG NO: GCTGGGGGCCCGGAAGTGGTAGGGGCCTCGGGAAGGGTTGGTGTTCATCCGCTTGCGGAGGAA 1280 AGCCAGGTACTTCAACTTGTTTCTGTAGAAATTGCCAGAAATGTTGATGCCTTCACAGCGTAC GACCACCACCTTCCGGCCCAGCAGTACCTGTTTAGCCACGATGGCCGCCAGGCGGCCCAGGAG ATGGCCTCGACCATCAAGCA RPL13A ADXCRIHRC.613.C1_x_at GCTGCCCTCAAGGTCGTGCGTCTGAAGCCTACAAGAAAGTTTGCCTATCTGGGGCGCCTGGCT SEQ ID CACGAGGTTGGCTGGAAGTACCAGGCAGTGACAGCCACCCTGGAGGAGAAGAGGAAAGAGAAA NO: GCCAAGATCCACTACCGGAAGAAGAAACAGCTCATGAGGCTACGGAAACAGGCCGAGAAGAAC 1331 GTGGAGAAGAAAATTGACAAATACACAGAGGTCCTCAAGACCCACGGACTCCTGGTCTGAGCC CAATAAAGACTGTTAATTCCTCGTGCCGAA RPL3 ADXCRIH.445.CB1_s_at CCTTGCTGGTGCAGACGAAGCGGCGGGCTCTGGAGAAGATTGACCTTAAGTTCATTGACACCA SEQ ID CCTCCAAGTTTGGCCATGGCCGCTTCCAGACCATGGAGGAGAAGAAAGCATTCATGGGACCAC NO: TGAAGAAAGACCGAATTGCAAAGGAAGAAGGAGCTTAATGCCAGGAACAGATTTTGCAGTTGG 1162 TGGGGTCTCAATAA RUVBL1 ADXCRAD_CN389613_s_at AAGAGCATGTCGAAGAGATCAGTGAACTTTTCTATGATGCCAAGTCCTCCGCCAAAATCCTGG SEQ ID CTGACCAGCAGGATAAGTACATGAAGTGAGATGGCTGAGGTTTTCAGCAGCAAGAGACTCCCC NO: AGGTGTGCCTGGCCTGGGTCCAGCCTGTGGGCGCTTGCCCCTGGGCTTGGGGCTGCCGTCCCC 918 ACTCAGGCGTGGGCTGCAGCGCTGTCAGTTCAGTGTGGAAAGCATTTCTTTTTAAGTTATCGT AACTGTTCCTGTGGTTGCTTTGAAAGAACCCTTC S100A14 ADXCRIH.2777.C1_s_at TGATTTGAATAATGGAGCTGGGAATATGGCTGGATATCTGGTACTAAAAAAGGGTCTTTAAGA SEQ ID ACCTACTTCCTAATCTCTTCCCCAATCCAAACCATAGCTGTCTGTCCAGTGCTCTCTTCCTGC NO: CTCCAGCTCTGCCCCAGGCTCCTCCTAGACTCTGTCCCTGGGCTAGGGCAGGGGAGGAGGGAG 1140 AGCAGGGTTGGGGGAGAGGCTGAGGAGAGTGTGACATGTGGGGAGAGGACCAGCTGGGTGCTT GGGCATTGACAGAATGATGGTTGTTTTGTATCATTTGATT SERPINB1 ADXCRIH.2353.C1_at TTTGGAAGCCACAAAATAGACAGACACCCTGACTGTTGAAGGGAGGTTTAAAAACAGATATTC SEQ ID AATTGAAATGTAAGAGAGCACCTCAATTGAGAGCCCAGGTTACGAAGACAAGCTTGCCTCGCC NO: TGACTTTTCTGTCCCTTGTTCTGCAGGATTAGTATTCTGTTACAGACTTCTAGTTTTAGACTC 1122 TTCATTAAAGGGCCAATGGTTATAACCTGC SERPINB1 ADXCRIH.2353.C1_s_at ATCTATAAAATTGCTATATCCTCCTGATAGCCATGGGAAAACATGATAAGATGGTCATTTATT SEQ ID TTGCAGTTAGAATTTTGGAAGCCACAAAATAGACAGACACCCTGACTGTTGAAGGGAGGTTTA NO: AAAACAGATATTCAATTGAAATGTAAGAGAGCACCTCAATTGAGAGCCCAGGTTACGAAGACA 1123 AGCTTGCCTCGCCTGACTTTTCTGTCCCTTGTTCTGCAGGATTAGTATTCTGTTACA SERPINB1 ADXCRAD_D11859_s_at GGGCTCTTGGACTGATATAAAACTTTGTNAAATGTAGTTCTTTGAATGGAGCTTGAAACGCCG SEQ ID CATATNCTTGCTCCCACAAGGATAGTGGGCATCATGAATTAATAAAACGTCCTAGGATTCTGC NO: A 2457 SERPINB1 ADXCRAD_W52010_s_at AAGGTGCAGCCTGGGATTCAAGTTCAAGGGGCTGCGAAACTTCTATTACTCATCACTTTAGAT SEQ ID ATGAAAGCATTTTAAATGTTTTTTTTAAATCCATTAAAAAAAAAAAACCTCTGTTACTAATTG NO: TTAGTTGCTTCTTGCAGGGTTATATCAGTTCCTAGCTTGAGGTTTTCCACGGGACTTTAAAAC 2834 CTCAGCA SHMT2 ADXCRAD_BP384660_s_at AACAAGACTTAGAAGGAGGGCCCAGGCACTTTCTGTTTGAACCCCTGTCATGATCACAGTGTC SEQ ID AGAGACGCGTCCTCTTTCTTGGGGAAGTTGAGGAGTGCCCTTCAGAGCCAGTAGCAGGCAGGG NO: GTGGGTAGGCACCCTCCTTCCTGTTTTTATCTAATAAAATGCTAACCTGCCCTGAGTTTCCAT 2559 TACTGTGGGT SHMT2 ADXCRAD_CX788770_at ACTGCCAAGCTCCAGGATTTCAAATCCTTCCTGCTTAAGGACTCAGAAACAAGTCAGCGTCTG SEQ ID GCC NO: 2669 SHMT2 ADXCRAD_CX788770_s_at TCAGCGTCTGGCCAACCTCAGGCAACGGGTGGAGCAGTTTGCCAGGGCCTTCCCCATGCCTGG SEQ ID TTTTGATGAGCATTGAAGGCACCTGGGAAATGAGGCCCACAGACTCAAAGTTACTCTCCTTCC NO: CCCTACCTGGGCCAGTGAAATAGAAAGCCTTTCTATTTTTTGGTGCGGGAGGGAAGACCTCTC 2670 ACTTAGGGCAAGAGCCA SLC19A1 ADXCRAG_U17566_s_at SEQ ID GAAGTACGTCCCAGCGGCCTCAGGGTCTAAGGAGCGCTAGTGCCTTGCCCACAGGTGCGGGAC NO: CATCTGATGTGATGTGAATACTCTTCCCACATACATTAAACACACTTA 1064 SLC19A1 ADXCRPD.7962.C1_s_at SEQ ID GCCGCGGGCTTCGTGAAGATCCGCTGGGCGCGCTGGTCCAAGCTGCTCATCGCGGGCGTCACG NO: GCCACGCAGGCGGGGNCTGGTCTTCCTTCTGGCGCACACGCGCCACCCGAGCAGCATCTGGCT 1389 GTGCTATGCGGCCTTCGTGCTGTTCCGCGGCTCCTACCAGTTCCTCGTGCCCATCGCCACCTT TCAGATTGCATCTTCTCTGTCTAAAGAGCTCTGTGCCCTGGTCTTCGGGGTCAACACGTTCTT TGCCACCATCGTCAAGACCATCATCACTTTCATTGTCTCGGACGTGC SLC9A3R1 ADXCRIH.2825.C1_s_at TTTTGTTAAGAGTGCAGTATTGCAGAGTCTAGAGGAATTTTTGTTTCCTTGATTAACATGATT SEQ ID TTCCTGGTTGTTACATCCAGGGCATGGCAGTGGCCTCAGCCTTAAACTTTTGTTCCTACTCCC NO: ACCCTCAGCGAACTGGGCAGCACGGGGAGGGTTTGGCTACCCCTGCCCATCCCTGAGCCAGGT 1169 ACCACCATTGTAAGGAAACACTTTCAG STOML2 ADXCRIH.3851.C1_at CTGCCTCCGTTATGAGATCAAGGATATCCATGTGCCACCCCGGGTGAAAGAGTCTATGCAGAT SEQ ID GCAGGTGGAGGCAGAGCGGCGGAAACGGGCCACAGTTCTAGAGTCTGAGGGGACCCGAGAGTC NO: GGCCATCAATGTGGCAGAAGGAAGAAACAGGCCCAGATCCTGGCCTCCGAAGCAGAAAAGGCT 1187 GAACAGATAAATCAGCAGCTGAGAGGCCAGTGCAGTTCTGGCGAAAGCCAAAGCTAAAGCTGA AGCTATTCGAATCCTGGCTGCAGCTCTGACACAACATAATGG TMPO ADXCRAD_CN272683_s_at CTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTC SEQ ID ATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAA NO: TTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACA 1061 AATTTTGCCGAGCTTTTTTTGCCCTATATTTCCCAGCATAATTTGATTAGAAAGT TMPO ADXCRIH.3127.C1_at GAAATTGTGAGAAGCTTCATTTAGTGTTTAAAAATGTGGGGAGATAAATCAGACTTAACATGT SEQ ID ATGTAAGATCAATTCACTTAAAAGTATGGTCCAAATAGCAAAAATAGGACCAGGTGAAACATG NO: TAGTCATTTTTTAAAAACATGTACTTGGTCTTTTGTGTGTGTCTGTTTTATTCCATTAGAATA 1197 AATGTGTCCTTGATGTAATGCAAAGCATTTCTTCCTGATTAAATTGTAGATGTAGACTTTAC TMPO ADXCRIH.3127.C1_x_at TCCCATACTGTTTTCAGCCTTTTGTTTATAATTAGAAATTGTGAGAAGCTTCATTTAGTGTTT SEQ ID AAAAATGTGGGGAGATAAATCAGACTTAACATGTATGTAAGATCAATTCACTTAAAAGTATGG NO: TCCAAATAGCAAAAATAGGACCAGGTGAAACATGTAGTCATTTTTTAAAAACATGTACTTGGT 1198 CTTTTGTGTGTGTCTGTTTTATTCCATTAGAATAAATGTGTCCTTGATGTAATGCAAAGCATT TCTTCCTGATTAA TMPO ADXCRIH.994.C1_s_at ATATCCTGGGATAGTGCATGTTCACCATCTATTTTGTCAGATAATGGGGCCTTTTAAAAAATA SEQ ID ATACTTTGCTTTCATGATATATTGTATTTTTGTGGAAAGTTAAGTTTAGCAATATATACTCTA NO: AAAGCAAATTTAATTTTTTTTAAGCCATAAAGAAATTATACTATATCCCAGTATCTGTATGTC 1247 TGTATAAAGCAGTGTATTATC TMPO ADXCRIHRC.3127.C1_at TGAAATCAAAATTGTGTGCTGGTCTAAATATACATCTTCGGCTTCTTCCTTTTTAGTAAGTAT SEQ ID TTTTATTTCAGATGTATTTAAAAATAACTTACATTTTTAGTGTGCTTTATGGTCAATGACTGT NO: AAAGTTGAAACTCAAATGAGTCAGTTTAAAATTTTTGTCTCATTTGATTCTATTGAAATTTTA 1320 ATCACCTACTACTTTAATCAAGTTATTCATGAGGTAAGTTTCAGCT TMPO ADXCRPD.3658.C1_at TTGTTCACAGTGTTGGCACATGGTAAGGGCTAAGACACTTGATTAGCATAATATTCAAAATTA SEQ ID GAAATTGTACACTATTGTACTCTCTTTCAAAAGGCAAACAGCCTAAAACTGTTTGGAAAAAAC NO: AGCTTGTACAGTATATTGTACACTTCCTGTGATAGACTAGTGGACTGATACACCCACTAATGC 1615 ACAGCAGTAATAGTCCACCTCTTTACACANTTATGCATGTTAAGTGACAAAAAAACTCACTTT AAAAGGCCAAATGATAAAAACATCAGCCTTGAGGCTCTTCGATATAGA TMPO ADXCRPD.12957.C1_at TAAACATGCAAACTCACTACCAAATTGGCTTATAGTAATATTAGGCCTTAGCAATTCCATTAA SEQ ID ATTAAGAGCAACTCATTATTGGAGAACACTTTCTAAGTTGAACTGTAATCATACAAACCGCAC NO: AGCCAAGCAAGTAACTTAAAGACATTGTTGTTAAAATAGTCCATTTTGGATTACCTATCTAAA 1676 TMPO ADXCRAD_BX482009_s_at AAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTT SEQ ID TGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATG NO: TTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTT 2649 CAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATT TCGCCTCAATAA TPK1 ADXCRAD_CD511474_at TAAAATGGAAGCGGTTGGACTGATGGTGTCTGAGGTTCTTTCCCACACTGAAATTCTAAATAT SEQ ID TGACACTTAGCAGTCATAGGGCTGATAATACACACAGTTACTGACTTAGCCTAAACAACCTGG NO: TGCATCGAAATGTAATCACCCTTTCTTTTGTAAAAGAGACCCATCTTCTATCTTCCTTTCCCA 2381 CCTTTTCTCTGTTTTTATGAAAACCCAACTGTTGGACATTCCAAACCATTGGATTTGA TPK1 ADXCRAD_CD511474_s_at ATTGACACTTAGCAGTCATAGGGCTGATAATACACACAGTTACTGACTTAGCCTAAACAACCT SEQ ID NO: GGTGCATCGAAATGTA 2382 TPK1 ADXCRAD_CD511474_x_at CATCCCAGTCTGATATTCACCTAAGTTTCCGGACCCTTTTCCTTAGCTGTAAAATGGAAGCGG SEQ ID TTGGACTGATGGTGTCTGAGGTTCTTTCCCACACTGAAATTCTAAATATTGACACTTAGCAGT NO: CATAGGGCTGATAATACACACAGTTACTGACTTAGCCTAAACAACCTGGTGCATCGAAATGTA 2383 ATCACCCTTTCTTTTGTAAAAGAGACCCATCTTCTATCTTCCTTTCCCACCTTTTCTCTGTTT TTATGAAAACCCAACTGTTGGACATTCCAAACCATTGGATTTG TPK1 ADXCRAD_CR745173_s_at TGGCCCGCGTGATTGTGGCATTTAAGGAGCAGTGGCCCATGTGACTGTGGCATTTTCGGCACT SEQ ID TTTCATTACTTTCTGCTTGACCGGAAGTTGAGGCTTAGCTATGTTTCCATCTTCAGTTTCTGA NO: AGACTAGTTATATATTCCTTACTAGAAATATATTCATAATATATAAAAGAAATATATCTGTGA 2592 TTTTAAAATTTTGCTACCAAAGAATGCATGTTCTGTGTGCCCTGAAAATGTTAC TPT1 ADXCRAD_NM_017627_s_at GGGACTGATGTCATCTTGAGCTCTTCATTTATTTTGACTGTGATTTATTTGGAGTGGAGGCAT SEQ ID TGTTTTTA NO: 1167 TPT1 ADXCRIH.18.CB1_x_at ACTCATCAATTAACTTCTACAGTGGAGACTACTTCTGGGACTGGAATATAAAAAAGAATCAAA SEQ ID GGTTCTGATTTTGAGTTGCAATAAAGGGAAAGACCATGCTCATAGCAGTGCCAACATCTGAAG NO: TGTGGAGCCTTACCCATTTCATCACCTACAACGGAAGTAGTTAACTGGAAGAGATTACCAAGA 1168 GAATAAAAAGAGACTCATTCAGTGGAACCAACCTCGTGCAGCCCGGG TPT1 ADXCRPD.14624.C1_at CCAGCTGGAGTTTTTGGGACGCTTTTGTGGGGGCACCGCTGAGTCCGGATAGTGGGACCCAAG SEQ ID TCGTCCTGCTCGGCCCCTGGGGAATAATCGTGTGGGGCGCAAGGTCTGTGGGAAGGGACTTGG NO: AGAGGAGGGAAGATGTCGCGGGAGTCTGCACAGGGTTTCCATGTGTTCCAATTCTTCGTCCCA 1733 TAATTCAAAGCTCGTGGCATTCTGTGGCCGACCGCTACCGAGCTAGCTCTTCCCTTTACTATT TCGCACTTGGTCTTGGAAAAGAT TPT1 ADXCRPDRC.14624.C1_at TTATGGGACGAAGAATTGGAACACATGGAAACCCTGTGCAGACTCCCGCGACATCTTCCCTCC SEQ ID TCTCCAAGTCCCTTCCCACAGACCTTGCGCCCCACACGATTATTCCCCAGGGGCCGAGCAGGA NO: CGACTTGGGTCCCACTATCCGGACTCAGCGGTGCCCCCACAAAAGCGTCCCAAAAACTCCAGC 2009 TGGGGCAGCCCTGGGGCCGATGCTGAAAAGTTGTCAGAGGCCCTCGGGCAGTCCCGAGATCTA CCCCAGGCCAGAGGGCCTGACCCTCCCTAAATGCGACGTTCT TPT1 ADXCRSS.Hs#S2979085_at GGGTGCAGCACAAGTTCCTTCATAGGACTTTAAGACTCTTTGGGATCTAGTCCCTGCGTATCT SEQ ID CTCCAGTTCTCCTTACCATTCTCCTGTATCTGCCTCTGGCTGCAGCTGTGCCACAGCCAGACT NO: CTGGAAGGAGCCTCTTGCTGTCAATTATCCAACAAGTGTTTACTGGGTACCCACTTCTGCCAG 2143 GCACTGGGTTAGAGGTTGGAGACATAGCAGTAAAGACTTGCTCTAGTGGAAGACAA TPT1 ADXCRSS.Hs#S3017795_at ACTACTCCAGATTTTTCACCTGCAAGTGGTAAGTCAGGCCAACTTCCGTTGGTGACCCGTTAT SEQ ID CTCTGCTTGAAAAAAGATAAGGAGATTCTCCACTTTGGCCTCAGCTCTTAGCTAGGTTCTTTA NO: GTCCAGCTAGGAGTTACTGAGCCTCCACCAAGAAGGTGAATCATTTGACCTCATTTAGCTCCT 2175 CCTCCTTATTTATCTTTATTAGAGCTTGCAGTGATGGAGAGTAAGTGATTGGGACCTCAAACT TCTAACACATAATTCTCTCAGGCGGGTTTGGAATGGTACTCTA TSPAN8 ADXCRIH.257.C1_at CTATGGTCCTGTATTGCCAGATCGGGAACAAATGAATCTGTGGATGCATCAACCTATCGTCAG SEQ ID TCAAACCCCTTTAAAATGTTGCTTTGGCTTTGTAAATTTAAATATGTAAGTGCTATATAAGTC NO: AGGAGCAGCTGTCTTTTTAAAATGTCTCGGCTAGCTAGACCACAGATATCTTCTAGACATATT 1298 GAACACATTTAAGATTTGAGGGATATA TSPAN8 RDCR023_G12_at AGTTGAGAGGCAGATACATTAAAAACCACTATAAATCACAATGAATTAATATTAATATCTATA SEQ ID ATACCCGAAGATTCTTTTCAATCTAGAAATGTTTTGGTTTAGTAACTGCTACTGAAAATAATT NO: TATAAAAGGAAATAGAAAGTATCTCAGGGGAAACTACCCTTTCCTTGACTACTGATCTTTTTC 1342 ACTGATCTTATCAAAATTAAAGAGGCTCTGCCCTGAAGGGGAATTGCTGTCATTAATACTTAA AGTATGTCGCTAAGATTTAAAGTAACTCAA TSPAN8 RDCR023_G12_x_at GAGGCAGATACATTAAAAACCACTATAAATCACAATGAATTAATATTAATATCTATAATACCC SEQ ID GAAGATTCTTTTCAATCTAGAAATGTTTTGGTTTAGTAACTGCTACTGAAAATAATTTATAAA NO: AGGAAATAGAAAGTATCTCAGGGGAAACTACCCTTTCCTTGACTACTGATCTTTTTCACTGAT 1343 CTTATCAAAATTAAAGAGGCTCTGCCCTGAAGGGGAATTGCTGTCATTAATACTTAAAGTATG TCGCTAAGATTTAAAGTAACTCAA TSPAN8 1_RDCR049_C08_at TTTTTATTCCTCTTGGAAATGCCTAAAACTACAGCAAGAGAAATTCTAGACTTCTGGATTTTT SEQ ID ATGCAGATGATTTAAACCAGATGATCATAACCTTTTTATGGAAGCAGTACGTATATTTAGCCC NO: CCAGGGACCTGAGATCCCCAGTGCTCCAGAGGAGACGCTCTGCAGAAGAATGTGTGTGTTCCA 1355 GAAAAGGGAGTAGGTCCTCTGGTGGCAGCTGCTACTGTGCAGTTTATATGGGGCCAGTTAGAT AGAGGCTGATTGGCC TUFM ADXCRIH.1094.C1_s_at TAGAGAAAGGCCAGCGTTTCACCCTGCGAGATGGCAACCGGACTATTGGCACCGGTCTAGTCA SEQ ID CCAACACGCTGGCCATGACTGAGGAGGAGAAGAATATCAAATGGGGTTGAGTGTGCAGATCTC NO: TGCTCAGCTTCCCTTGCGTTTAAGGCCTGCCCTAGCCAGGGCTCCCTCCTGCTTCCAGTACCC 1146 TCTCATGGCATAGGCTGCAACCCAGCAGAGGGCAGCTAGATGGACATTTCCCCTGCTCGGAAG GG TXN ADXCRIH.324.C1_s_at AGTCAAATGCATGCCAACATTCCAGTTTTTTAAGAAGGGACAAAAGGTGGGTGAATTTTCTGG SEQ ID AGCCAATAAGGAAAAGCTTGAAGCCACCATTAATGAATTAGTCTA NO: 1124 TXN ADXCRPD.10055.C1_at TTTTTCCTGTCTTACCTGGATCTTGCAATAAAGGATGCCTGGTTTAATTTTCTTGAAAATCAC SEQ ID ATTAGGGAAGGCTTTGAATGAAATTGATCTGGAACAATAAGTGATGATTTGGAAAAACAATTG NO: CTATACTTCTATGTAACCTGCTGCAGCTCTCCCCATGTCTCCACCTCTAGAGGTGGGGTTCAG 1842 GGATTTGCATAACTAAAAAATTTATGAAAGTGTTGTCCTACCTTTCTCAGGAACACCATTTGT GAATTATTTTCCCAAATATCGAGGGAGGTGATCTTCT UCK2 ADXCRPD.10643.C1_at AAGATTAGATTCCTGCCTCGGGCCAGGTGAAAGGAAGGCAGGAAAGAGATTCTGTTTCCTGAC SEQ ID CCAACATTATCACAAAAGACTGTAACAAGGGCTGTGGGAGTTATGGACCAGGAACCTGGTTGA NO: AAACCATTATAAATCATAACACCACAAGGACCTATATTTTGCTTTTTAGGACATTGTAGTAGG 1461 TGGGTAGTTTTCATCCTCTTGCTTTTTAAAATCTATCTTGCCCAGAAGTTTATTGGGCATTTC TATGGAAACACAACACCTCTCTTAAAT UCK2 ADXCRPD.9879.C1_s_at SEQ ID GCAGGCCGCATTGACCCGTCTCCATCGGACCCCAGCCCCTATCTCCAAGAGACAGAGGAGGGG NO: TCAGGAGGCACTGCTCATCTGTACATACTGTTTCCTATGACATTACTGTATTTAAGAAAACAC 1541 CATGGAGATGAAATGCCTTTGANNNNNNNNNNNNNNNNGTACTTTGGAACGACAAAATGAAAC A UCK2 ADXCRPD.5097.C1_s_at ACTGGCATTCCAGGTCAGCTTGGCTGTGGTCTTAGAGGCAGGGAGTGCCTACCCAGTCCTGCC SEQ ID TCAGGAGCAGGGTGAGTAGCTAAATACAGACTTAGGCTTTTTTTCCCCCCTTTTAAGATGCTT NO: GCTCCTCTCCCTTTTCTTTTTACCACCCTACCTTTATTGTTAGTGGTTACAAAGTGACCACAT 1651 ATTATGTACTTTGCTGTAA UCK2 ADXCRPD.14415.C1_s_at TAGCGGCAAGTCTTCCGTGTGTGCTAAGATCGTGCAGCTCCTGGGGCAGAATGAGGTGGACTA SEQ ID TCGCCAGAAGCAGGTGGTCATCCTGAGCCAGGATAGCTTCTACCGTGTCCTTACCTCGGAGCA NO: GAAGGCCAAAGCCCGGAAGGGCCAGTTCAACTTTGACCACCCGGATGCCTTTGACAATGAACT 1702 CATTCTCAAAACAC UCK2 ADXCRPD.15116.C1_at CCCCTCTGCCAGACAGTGGGTTGAACACACATGTACACCTGAGGAGGAGGGTCTGACGAGGGC SEQ ID TGCCTCAGAGTCAGAGGCAGCAGGACTAGCTCTGTATGTTCGACCTCATGTCTGGCCCATCTT NO: GAGTCCCAGGCTCATACAAAATCACCTGTGTTCAGATACAGATTCAACTCAGTATTTAATGAG 1715 CCAAGCACTACTTGAAGCATCTTGACAGTCCTTCTCTTCACATAAGCCCCGACAATCACATCT GCAAGGTACGTATCAAGTCCCTACGTTCCGAGACA UCK2 ADXCRPD.14599.C1_at TTAAACTCCACCAAGACCCAGCAAGAAGAGCCTCATGGCAGGCTAGGACTGAGTTCTTCCCAG SEQ ID AAGACAGGTCTAAAACACAAGCTTTTCCACCTTAACAATGGATGTCTCCTGACCCCTTCCTCC NO: AGAAATCAAATGGCCAATCTGATGCCCACTTCAGCTTCTGTCATCCCTCTGTAGTCAGACAAG 1728 GAGGGCTCGCTCAGCTTGCATTTCCTTCCTGAAGAGTATTCACTACCTCTCTTGTTCAAACAC TATGTATCACTCAAT UCK2 ADXCRPDRC.5097.C1_at GCAAAGTACATAATATGTGGTCACTTTGTAACCACTAACAATAAAGGTAGGGTGGTAAAAAGA SEQ ID AAAGGGAGAGGAGCAAGCATCTTAAAAGGGGGGAAAAAAAGCCTAAGTCTGTATTTAGCTACT NO: CACCCTGCTCCTGAGGCAGGACTGGGTAGGCACTCCCTGCCTCTAAGACCACAGCCAAGCTGA 1983 CCTGGAATGCCAGTCCCCGGTATGAGGAAGGCAGC UCK2 ADXCRPDRC.5097.C1_x_at GCCTTTTTGTCTGTCTTTATTTACAGCAAAGTACATAATATGTGGTCACTTTGTAACCACTAA SEQ ID CAATAAAGGTAGGGTGGTAAAAAGAAAAGGGAGAGGAGCAAGCATCTTAAAAGGGGGGAAAAA NO: AAGCCTAAGTCTGTATTTAGCTACTCACCCTGCTCCTGAGGCAGGACTGGGTAGGCACTCCCT 1984 GCCTCTAAGACCACAGCCAAGCTGACCTGGAATGCCAGTCCCCGGTATGAGGAAGGCAGCAGA ACGCCCAGAGACA USH1C ADXCRIH.2211.C1_s_at SEQ ID ACCAGGGCCAGATAAGGAACAGCTCGGGCCACTCTTCTGAAGGCCAACGTGGAGGAAAGGGAG NO: CAGCCAGCCATTTGGGAGAAGATCTCAAGGATCCAGACTCTCATTCCTTTCCTCTGGCCCAGT 1242 GAATTTGGTCTCTCCCAGCTCTGGGGGACTCCTTCCTTGAACCCTAATAAGACCCCACTGGAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAATTGCTGCCAGGATTGTCACTCCA USH1C ADXCRPD.18376.C1_s_at GTCCATCAAAGTGAGACACATCGGCCTGATCCCCGTGAAAAGCTCTCCTGATGAGCCCCTCAC SEQ ID TTGGCAGTATGTGGATCAGTTCGTGTCGGAATCTGGGGGCGTGCGAGGCAGCCTGGGCTCCCC NO: TGGAACATCGGGAAACCAAGGAGAAGAAGGTCTTCATCAGCCTGGTAGGCTCCCGAGGCCTTG 1421 USH1C ADXCRAD_NM_025034_at ACATGCACACATAGGATTTTACTTGAAAAAAATAATAAAGGAGACAGATATGTCAAATCTTTT SEQ ID TCAGGCACTAATAACATGTAAATGTAAAAGAACTAGAATCTTCTCCACATACCACCTCCCATC NO: AGAAATCATGTCCTTGAAAGTGCTGTTGATAAAGAAATAGGGTTGCCTTTCCCCTATTCCTTA 2848 ATCTAATTATTCCAGAAACAGCTGTCATTTTGGTTTTCATT WDR59 ADXCRPD.15558.C1_s_at CAGTGTTACCCTGTAAGGTGTTAGCCTTAAACCACCGAGCAGCGTTCTCTTGATGCCAGTGCA SEQ ID GAGACCAGAGTCAGATGCCCGAGGACAGTGGGTAGGAATTTCATCAACAAATGGACCTATGGC NO: ATCATGGCTTTAGAAGCTGGTACATTTACTGAGCTGATGGACAGTGGCCTTCTAAAATATGAC 1764 ACTTAAATTGTAAATATGCACTGTACTTAAGGATTCTTAAGATGTATTTTTTTGTTATTTCTC CTCCAGCTGCTATCCCTTGGCTAATAAA WDR59 ADXCRAD_AA393120_at CCCCTAGAAATCTCCTGGAAGAGAGGAAATCAGATCAACTGGGGCTGCCTCAGACCTTGCAGC SEQ ID AGGAATTCTCCCTGATCAATGTGCAAATCCGGAATGTCAATGTGGAGATGGATGCGGCAGACA NO: GGAGCTGCACAGTGTCTGTGCACTGCAGCAACCATCGTGTCAAGATGCTGGTGAAGTTCCCTG 2596 CACAGT ZFP36 ADXCRIH.2153.C1_s_at GGGAATCCTGGTGCTCAAATTACCCTCCAAAAGCAAGTAGCCAAAGCCGTTGCCAAACCCCAC SEQ ID CCATAAATCAATGGGCCCTTTATTTATGACGACTTTATTTATTCTAATATGATTTTATAGTAT NO: TTATATATATTGGGTCGTCTGCTTCCCTTGTA 1194

TABLE 8 Genes and corresponding Almac probesets predicting resistance to 5-FU. There can be multiple Almac IDs/probesets associated with a given gene. Almac SEQ ID Gene Probe ID Probe Sequence NO ACTN1 ADXCRAD_BM714793_at AAGAGAATTTATGTGGCTTCTCATTTTTAAATCCCCTCAGAGGTGTGACTAGTCTCTTTATC SEQ ID AGCACACACTTAAAAAATTTTTAATATTGTCTATTAAAAATAGGACAAACTTGGAGAGTATG NO: GACAACTTTGATATTGCTTGGCACAGATGGTATTAAAAAA 2737 ACTN1 ADXCRAD_CX871590_s_at TCTCCTGCCTGGGTTCGGTTTCAGCTCCCAGCCTCCACCCGGGTGAGCTGGGGCCCACGTGG SEQ ID CATCGATCCTCCCTGCCCGCGAAGTGACAGTTTACAAAATT NO: 2469 ACTN1 ADXCRAD_M95178_at GACGTCAGCCTGTACAGGCTCCCAGGGGTGGCGTCAAATGCTATTGAAATTGCGCTGAATCG SEQ ID TATGCTTTTTCC NO: 2816 ACTN1 ADXCRAD_M95178_x_at GTGCGCCGTGCCCACAGATGTGAAATGAATGTAATCTAATAGAAGCCTAATCAGCCCACCAT SEQ ID GTTCTCCACTGAAAAATCCTCTTTCTTTGGGGTTTTTCTTTCTTTCTTTTTTGATTTTGCAC NO: TGGACGGTGACGTCAGCCTGTACAGGCTCCCAGGGGTGGCGTCAAATGCTATTGAAATTGCG 2817 CTGAATCGTATGCTTTTTCCTTTTGA ACTN1 ADXCRAG_BC011987_s_at GGAAAGATTAACTATTTGCACCGAAATGTCTTGTTTTGTTGCGACATAGGAAAATAACCAAG SEQ ID CACAAAGTTATATTCCATCCTTTTTACTGATTTTTTTTTCTTCTATCTGTTCCATCTGCTGT NO: ATTCATTTCTCCAATCTCATGTCCATTTTGGTGTGGGAGTCGGGGTAGGGGGTACTCTTGTC 934 AAAAGGCACATTGGTGCATGTGTGTTTGCTAGCTCACTTGTCCATGAAAATATTT ACTN1 ADXCRSS.Hs#S3748482_at GGCACAGAGGAAACCCGCTGAGCCTGCTTCCTTAGTTCTGGCAGATGGGTCAGCCCCCACAG SEQ ID GACTCAGGATTCAATTTAGCCCGGGGTTCTGGCTCCATCTCCCACAGTGCCGGTGCCAGTGT NO: GCTCCTAAGTACTGTTTGTGCAAACCTGGCTCTGACTGAGACAAGGAGCCTTAGGAGTAGTA 2203 GGGACAGGAGACACAGCAAACTAGGGCTCAGA ATM ADXCRAD_BU501514_s_at ATACAGCAGGCCATAGACCCCAAAAATCTCAGCCGACTTTTCCCAGGATGGAAAGCTTGGGT SEQ ID GTGATCTTCAGTATATGAA NO: 2467 ATM ADXCRAD_N29457_at GCCAGTTCTCCGCAGTGAAATGCTAGGAAAATGTCTTTAGAAGACAGAATTCTTTCTGAATG SEQ ID CAAGTCTAAAATGCTTAAAAGAGATTAAAGGTTTTAAAGACCCAAATCAGAAATATCCATTA NO: GATACATCTCATTTGAATCCTAAGAGTTTAAACATAATAAACGCTGTATTTATTTATTTTAT 2812 TTCTTTTTTATTTTTTTGAGGCAGAGTCTCACTTTGTTGCCCAGGCTGGAGTGCAGTGGTGC AGTCTTGGCTCACTGCAGCCTGTCTTCTGGGTTAAAACGATTCTC ATM ADXCRAG_U67093_s_at TTGGTCATTATAGTATATGCCTAAAATGTATGCACTTAGGAATGCTAAAAATTTAAATATGG SEQ ID TCTAAAGCAAATAAAAGCAAAGAGGAAAAACTTTGGACATCGTAAAGACTAGAATAGTCTTT NO: TAAAAAGAAAGCCAGTATATTGGTTTGAAATATAGAGATGTGTCCCAATTTCAAGTATTTTA 1071 ATTGCACCTTAATGAAATTATCTATTTTCTATAGATTTTAGTACTATTGAATGTATTACTTT ACTGTTACCTGAATTTATTAT ATM ADXCRPD.14974.C1_at ATTTGTTAATCCTCCGCAGCTGGGATGAACATTTTCCTAAGGATGGAGAAGAGATAATACTC SEQ ID ACTAATACACGAGTCAGTAGTTTTACTTTCAGGTGGCTTTTAATCTGATGTTTATCTAATAT NO: GATGACAGCTGGGGGACAGAGAAATGTTCCACTTCTACCTATGTATCAAACTAGATACCTAA 1768 GCCCTTCC ATM ADXCRPD.3071.C1_s_at ATTTGGGACTCTGCCATATTCTTTCCGTCTATTTAAAAGGATTGGATTATGAAAATAAAGAC SEQ ID TGGTGTCCTGAACTAGAAGAACTTCATTACCAAGCAGCATGGAGGAATATGCAGTGGGACCA NO: TTGCACTTCCGTCAGCAAAGAAGTAGAAGGAACCAGTTACCATGAATCATTGTACAATGCTC 1493 TACAAT ATM ADXCRPDRC.14974.C1_s_at AACTACTGACTCGTGTATTAGTGAGTATTATCTCTTCTCCATCCTTAGGAAAATGTTCATCC SEQ ID CAGCTGCGGAGGATTAACAAATGGGTGATTGAGCTTTCTCCTCGTATTTGGACCTTGAAGGT NO: TATATAAATTTTTTTCTTATGAAGAGTTGGCATTTCTTTTTATTGCCAATGGCAGGCACTCA 2017 TTCATATATGATCTCCTCACCTTCCCCTCCCCTAAAACCAATCTCCAGAACTTTTTGGACTA TAAAT ATM ADXCRSS.Hs#S11049845_at CCTTGTTTGCCTTGGTATCATTCAGCGGAGGCTGCAGAACAGCAAAGATTGCTATCTGTTCC SEQ ID TTCCTCTGGAAGCTTCGTCCCAGAGGGGAATGCGCCAGATGCCTGCTGGAGCTCTCCTGTAT NO: GTGGTGTCTGTCGACCCCTGCTGGGAGGTGTCTCCCAGTCAGGAGGCACGGGGGTCAGGGAT 2084 CCACTTGAGGAGGCAGTCTGTCCCTTAGTAGAGCTTGAGCGCTGTGTTGGGAGATCCAA ATM ADXCRSS.Hs#S11049845_x_at CCTTGTTTGCCTTGGTATCATTCAGCGGAGGCTGCAGAACAGCAAAGATTGCTATCTGTTCC SEQ ID TTCCTCTGGAAGCTTCGTCCCAGAGGGGAATGCGCCAGATGCCTGCTGGAGCTCTCCTGTAT NO: GTGGTGTCTGTCGACCCCTGCTGGGAGGTGTCTCCCAGTCAGGAGGCACGGGGGTCAGGGAT 2085 CCACTTGAGGAGGCAGTCTGTCCCTTAGTAGAGCTTGAGCGCTGTGTTGGGAGATCCAAGGA GCTGGCAGGCAGGAACGTTTAAGTCTGTTGAGGCTGCACCC ATP2B4 ADXCRAD_BQ223439_s_at CCCCATTCAGGTCATGGTAGAATCTACTCCTTGGTAGTCACTTGTCATTTTTANAGAAATGA SEQ ID TGACAATCCTCTTGGCATCACCCCACCCCACATTCTCCCCGATGGTCCTCTCCTGAATTCTG NO: GATTTTGTCCTACAAGTCTGTGCCATTTATAA 2627 ATP2B4 ADXCRAD_CN299966_at ACAAATGGTGATATCAAAGCAACGTATACCCCAGTCCAGTGTGTGTTGCCATAATTTGCAAT SEQ ID TCAGCTTAACAGTGCACCCAATCTATATTTGCATTTTG NO: 2523 ATP2B4 ADXCRPD.10094.C1_at AGCCATCTTTATACTTAGGGAAGAAAAATTGTTGGGTTCTAGACTTTTTTAATATAAATTTT SEQ ID GTTGATATGGAATTAGGTAAGTTTAAGTGTCTATGTGCATATGTTTTTATATAAGTTTTTTC NO: TATTCAGTTTCACTGATCCAACTGGCAGTGGGTAAATATGGCATAAGTTAATAACACTTTTC 1845 CCCAAAATGGTGCTTTGGATTTGAAAAGGGTCTGATGGGGAGAAGGAGAACGTATCATCCTA GCTTCCTCTCTTATAAACCTAGAAAAACGGGTAGTAAACTGTGGATAGTCA ATP2B4 ADXCRPD.11491.C1_at TTCATTTTTCTTCCCCTCTGCTAGTTTGGAAGTTATATTATACCAAGTTTTTTAGTATTAGC SEQ ID CTAGAAATCTTAACATAAAGACTTCTAATAAGCAATATCTTTAATTTTTTTTNCCTACCCAA NO: TACTAGATCATGAGCATTTTCCCACATCATAAAGAATTGGTCACAAGTCAGCCCCAAACATA 1498 GTCCAGTGGAATCCAATGATA ATP2B4 ADXCRPD.5728.C2_at ATGGGAGCTCATCTCCTTCCATCTCTCCTAATCAAGAGCAAAGGGAACAGCAGGCCTAACAG SEQ ID CAGGGTTGGGAAGGCAAA NO: 2284 ATP2B4 ADXCRPD.5728.C2_x_at CAATAGTCAATCTTTGGTTTTTCTTTTTGGTACAAAAATACCAGTGCTTGTTATACTAGTTA SEQ ID CTAAAAGAAGAAGAAACTCAAAATTCCTATCTGCGTGCTAATTTGAAAAGAACAACGTAGAT NO: AGATTTGTTGGCACATATATATGGCATATTCACATATGGCATATATACATATGGGGAGAAAA 2285 CATGAACCAAAGGCCAATTCAGTTATGGGAGCTCATCTCCTTCCATCTCTCCTAATCAAGAG CAAAGGGAACAGCAGGCCTAACAGCAGGGTTGGGAAGGCAAA ATP2B4 ADXCRPDRC.5728.C1_s_at TGGAAGGAGATGAGCTCCCATAACTGAATTGGCCTTTGGTTCATGTTTTCTCCCCATATGTA SEQ ID TATATGCCATATGTGAATATGCCATATATATGTGCCCACAAATCTATCTACGTTGTTCTTTT NO: CAAATTAGCACGCAGATAGGAATTTTGAGTTTCTTCTTCTTTTAGTAACTAGTATAACAAGC 2056 ACTGGTATTTT AXL ADXCRAD_NM_021913_s_at GTTCTAACCCTATACTGTAGTATTCTTTGGGGTGCCCCTCTCCTTCTTAGCTATCATTGCTT SEQ ID CCTCCTCCCCAACTGTGGGGGTGTGCCCCCTTCAAGCCTGTGCAATGCATTAGGGATGCCTC NO: CTTTCCCGCAGGGGATGGACGATCTCCCACCTTTCGGGCCATGTTGCCCCCGTGAGCCAATC 1586 CCTCACCTTCTGAGTACAGAGTGTGGACTCTGGTGCCTCCAGAGGGGCTCAGGTCACATAAA ACTT C19orf10 ADXCRIH.3832.C1_s_at AGAGAACAGAGGGTCCAGGGCCCTCCTGGCTCCCAACAGCTTCTCAGTTCCCACTTCCTGCT SEQ ID GAGCTCTTCTGGACTCATGATCGCAGATCCGGGGCACAAAGAGGGTGGGGAACATGGGGGCT NO: ATGCTGGGGAAAGCAGCCATGCTCCCCCGACCTCCAGCCGAGCATCCTTCATGAGCCTGCAG 1178 AACTGCTTTCCTATGTTTACCCAGGG CALU ADXCRAD_BP380290_s_at GAATGCTGATGGTTTCATTGATCTAGAAGAGTATATTGGTGACATGTACAGCCATGATGGGA SEQ ID ATACTGATGAGCCAGAATGGGTAAAGACAGAGCGAGAGCAGTTTGTTGAGTTTCGGGATAAG NO: AACCGTGATGGGAAGATGGACAAGGAAGAGACCAAAGACTGGATCCTTCCCTCAGACTATGA 2344 TCATGCAGAGGCAGAAGCCAGGCACCTGGTCTATGAATCAGACCAAAACAAGGATGGCAAGC TTACCAAGGAGGAGATCGTTGACAAGTATGACTTAT CALU ADXCRAD_CN403921_s_at GATAATTTAATAATGCCACCAACTCTGGCTTAGTTAAGTGAGAGTGTGAACTGTGTGGCAAG SEQ ID AGAGCCTCACACCTCACTAGGTGCAGAGAGCCCAGGCCTTATGTTAAAATCATGCACTTGAA NO: AAGCAAACCTTAATCTGCAAAGACAGCAGCAAGCATTATACGGTCATCTTGAATGATCCCTT 1564 TGAAATTTTTTTTTTGTTTGTTTGTTTAAATCAAGCCTGAGGCTGGTGAACAGTAGCTACAC ACCCATATTGTGTGTTCTGTGAATGCTAGCTCTCTTGAATTTGGATATT CALU ADXCRAD_CX788634_s_at ATGTCATTGAAAGTGCCTTTAACGAAAGAAATGGTCACTGAATGGGAATTCTCTTAAGAAAC SEQ ID CCTGAGATTAAAAAAAGACTATTTGGATAACTTATAGGAAAGCCTAGAACCTCCCAGTAGAG NO: TGGGGATTTTTTTCTTCTTCCCTTTCTCTTTTGGACAATAGTTAAATTAGCAGTATTAGTTA 1218 TGAGTTTGGTTGCAGTGTTCTTATCTTGTGGGCTGATTTCCAAAACCACATGCTGCTGAATT TACCAGGGATCCTCATACCTCACAATGCAAACCACTTACTACCAG CALU ADXCRPD.558.C1_at GTAAACCAAGTTTTATATTCTGCAATGCGAACAGGTACCTATCTGTTTCTAAATA SEQ ID NO: 1563 CAPN2 ADXCRAD_AK023851_s_at AGAATGGCAGTTGTCAGTCCTGTCCGTGTAACAGAGGAGTGAAGTGGTGAGGAGGGCAGGTC SEQ ID TAAGGCACTGGCAGCTCTTTTCCATGGATTTTGAACTCTGGAGGAAGGCAGCAACTAAATAA NO: CTGTCTCATTCTGCTATTATGCATTGTATTAGCAAAGTGAAAATATAGTCTATCTGGTTACA 2826 AATAACACTAACTTGCTTAAAACTTTACATATCCTAGGAAATATCTCTACCCCTAGATTGCA ATGTAGAGTCAACCCCATCT CAPN2 ADXCRIH.1382.C1_at GTATCTGGACCTCAAAATTATGGGAACATTTACTTAAACGGATGATCATAGCTGAAAATAAT SEQ ID GATACTGTCAATTTGAGATAGCAGACGTTTCACACATCAAGTAAAAGATTTGCATATCATTA NO: TACTAAATGCAAATGAGTCGCTTAACCCTTGACCAGGTCAAAGAAAAGCTTT 2233 CAPN2 ADXCRIH.1382.C2_s_at TGGCTCTGTTTCTCAGTACTTTGAAGTTATAACTAATCTGCCTGAAGACTTCTCATGATGGA SEQ ID AAATCAGCCAAGGACTAAGCTTCCATAGAAATACACTTTGT NO: 2234 CAPN2 ADXCRPD.2526.C1_at GGCACGAGAATGTACTCTCCTGGCGGCAGCTTGAAGCGGTTGAGCACCTCCCGGAGGTTGAT SEQ ID GAAGGTGTCTGAGCGCTCCCTGGCGCGATTCGTCAGGAAGAAGTTTTTGCTGAGGTGGATGT NO: TGGTCTGCCCACTTAACTCCTCTGGAACCTCATAGATGCCAAAGCCGATGGTGTGCATGTCC 1521 TCGCCCATCTTCCTCTGCCGCCGTCGGTGCTTCTGAATGAG CAPN2 ADXCRPD.6630.C1_s_at TGCGCTTGATCAACTGAACCAGTATGCCAAAACCAGGCATCCAATTTGTAAACCAATTATGA SEQ ID TAAAGGACAAAATAAGCTGTTTGCCACCTCAAAACTTTATGAACTTCACCACCACTAGTGTC NO: TGTCCATGGAGTTAGAGGGGACATCACTTAGAAGTTCTTATAGAAAGGACACAAGTTTGTTT 1900 CCTGGCTTTACCTTGGGAAAATGCTAGCAACATTATAGAAATTTTGCCTTGTTGCCTTATCT TCTTCCAAATGTACTGTTAA CAPN2 ADXCRPD.9976.C1_at TCGGCTCCGGTGACCGAGTACGCGTGCCCCTTCACCAGCTTCTGAAACGTGAATGGCCTCCG SEQ ID AGTCCCCGGCGCTGGTGATGTCGATGGAGCAGCCAAGGAGAGAGCCTTTTTGCAGAGCTTTC NO: TGGATGATCTTGAACAGGTTGGGAGGGGGCTTCTTCAACTCATACCACTCAGCAATGCTCCG 1552 GTGAAGTCTTCGAAGCCCTCAGTGGTGGCACCCCCTGATAGTGCTTCATAGCATCCGTTGAT CTTGCGTATGCCTTC CAPN2 ADXCRPDRC.9976.C1_at ACGCGTACTCGGTCACCGGAGCCGAGGAGGTTGAAAGTAACGGAAGCCTACAGAAACTGATC SEQ ID CGCATCCGAAATCCCTGGGGAGAAGTGGAGTGGACAGGGCGGTGGAATGACAACTGCCCAAG NO: CTGGAACACTATAGACCCAGAGGAGAGGGAAAGGCTGACCAGACGGCATGAAGATGGAGAAT 1965 TCTGGATGTCTTTCAGTGACTTCCTGAGGCACTATTCCCGCCTGGAGATCTGTAACCTGCCG AAGACCCAGCTTGAG CAPN2 ADXCRSS.Hs#S2984172_at GAGCCACCACGGGTAGCAAAGTGAACTTCCCCCGAATCACGGTTAAGCCCCCTGGGCCACAT SEQ ID GGAGCTGTCATCTGCAGTTTTTCCCACCTCGGAGGCCTGACCCTGTGCTCTCCATAATCAAT NO: GAGTAGATGTGGCCCTTTATGTTCCCTGAGGCTTCCCTGACTGCTCATTAAAAGGATCTGCT 2154 CAGTCCTAGTGAATTGATTTACTTTGCCACAGTCCTTGAAGGATGCTACAGATCAAAAGGTG TCCAGGAAAGTGATCTTAAAGATGCTGACACTACTCCCAGTT CAV1 ADXCRIH.1095.C2_at TTTATTCCTCCTGCTCATATTGTGATTCTGCCTTTGGGGACTTTTCTTAAACCTTCAGTTAT SEQ ID GANNNNNNNNNCATACACTTATTGGAACTCTGCTTGATTTTTGCCTCTTCCAGTCTTCCTGA NO: CACTTTAATTACCAACCTGTTACCTACTTTGACTTTTTGCATTTAAAACAGACACTGGCATG 1272 GATATAGTTTTACTTTTAAACTGTGTACATAACTGAAAATGTGCTATACTGCATACTTTTTA A CAV1 ADXCRPD.1261.C1_s_at TCAAGTTCCAAGTTGCTAATACAGCAACAATTTATGAATTGAATTATCTTGGTTGAAAATAA SEQ ID AAAGATCACTTTCTCAGTTTTCATAAGTATTATGTCTCTTCTGAGCTATTTCATCTANNNNN NO: NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTGCATGTGGA 1881 TCAACCATCGCTTTATT CCND1 ADXCRAD_BM551840_x_at TGAGGGACGCTTTGTCTGTCGTGATGGGGCAAGGGCACAAGTCCTGGATGTTGTGTGTATCG SEQ ID AGAGGCCAAAGGCTGGTGGCAAGTGCACGGNGCACAGCGGAGTCTGTCCTGTGACGCGCAAG NO: TCTGAGGGTCTGGGCGGCGGGCGGCTGGGTCTGTGCATTTCTGGTTGCACCGCGGCGCTTCC 1593 CAGCACCAACATGTAACCGGCATG CCND1 ADXCRAD_BQ436873_at AAAAATAGTATTTGCATAACCCTGAACGGTGGGGGAAGAGGGGTGTGCTACANATGATAGAG SEQ ID GGATTTTATACCCCAATTATCAACTCCGTTTTTATATTAATG NO: 2640 CCND1 ADXCRPD.13939.C1_at TTCACATTGTTTGCTGCTATGTGGAGGATCAGTGTTTTGTGTTACAATGTCATATACTGCCA SEQ ID TGTACTAGTTTTAGTTTTCTCTTAGAACATTGTATTACAGATGCCNNNNNNNNNNNNNNNNN NO: NNNNNNNATGTGATCAATTTTGACTTAATGTGATTACTGCTCTATTCCAAAAAGGTTGCTGT 1727 TTCACAATACCTCATGCTTC CCND1 ADXCRPD.15960.C1_at TGCCCGACAAACCTCCACTGGATGGTTTGTCACTGGATGGTTTGTTGGGGTGGTGGTCACAG SEQ ID GCGCAAAGGACATGCACACGGCCACGCTACGCTACTGTAACCAAG NO: 1817 CCND1 ADXCRPD.16054.C1_at ACCAAGTAGCTGTGGGTTGAACCTGGACGTGAGCTGGTTGCAGGGCCGTTGGGTAGAAAACC SEQ ID AGCATCTCATAAACAGGTCACTACAAAAATAGGAAGAGTATAAAAATAGAATATATTATGTC NO: ACTATTTCGTCTTCTCTTTATAGTAGCGTATCGTAGGAGTGGGACAAGGTGGCCTTTCCCGA 1752 CACTGCTACGCTGGTCTGTGCCCGACAAACCTCACCTGATGTTGTACCTGAGTACGTTACTA AATCCTCAAGACCTTACACACAGC CCND1 ADXCRPD.3501.C1_s_at TCTGTCTGAACCACGCGGGGGCCTTGAGGGACGCTTTGTCTGTCGTGATGGGGCAAGGGCAC SEQ ID AAGTCCTGGATGTTGTGTGTATCGAGAGGCCAAAGGCTGGTGGCAAGTGCACGGGGCACAGC NO: GGAGTCTGTCCTGTGACGCGCAAGTCTGAGGGTCTGGGCGGCG 1592 CCND1 ADXCRPD.3980.C1_s_at GGAGGTGGACCTGGCTTGCACACCCACCGACGTGCGGGACGTGGACATCTGAGGGCGCCAGG SEQ ID CAGGCGGGCGCCACCGCCACCCGCAGCGAGGGCGGAGCCGGCCCCAGGTGCTCCCCTGACAG NO: TCCCTCCTCTCCGGAGCATTTTGATACCAGAAGGGAAAGCTTCATTCTCCTTGTTGTTGGTT 1679 GTTTTTTCCTTTGCTCTTTCCCCCTTCCATCTCTGACTTAAGCAAAAGA CCND1 ADXCRPDRC.16054.C1_at GTAGTGACCTGTTTATGAGATGCTGGTTTTCTACCCAACGGCCCTGCAACCAGCTCACGTCC SEQ ID AGGTTCAACCCACAGCTACTTGGTTTGTGTTCTTCTTCATATTCTAAAACCATTCCATTTCC NO: AAGCACTTTCAGTCCAATAGGTGTAGGAAATAGCGCTGTTTTTGTTGTGTGTGCAGGGAGGG 2013 CAGTTTTCTAATGGAATGGTTTGGGAATATCCATGTACTTGTTTGCAAGCAGGACTTTGAGG CAAGTG CD44 ADXCRAD_BM840380_s_at GAGATCACTTCCAGCCTAATGTGCATTTGGCTGGAATATGGTTGTCTCAGAATAACATCATG SEQ ID CACTCGGGCTTTTATACTTCTGCCTTTAGGGGACTGTGGCAGCATGGCATGGGTCAAGAAGT NO: ACTTCTCCTTCATCTTCCTTTGATGTCGGTAACTCATCCTTTCTGCACTGCGGGAGTTGTTA 2459 ATGCTTTTGTGTCCTCCAGTTCACATGCTGATTGCTAAGAAGAAAATGAGCATGAGTGAACC CAAAGCTGCTGAAACATTCTGCGTTTATGCAACTTCCTTG CD44 ADXCRAD_BP233968_at TGAATGGGTCCATTTTGCCCTTCCATAGCCTAATCCCTGGGCATTGCTTTCCACTGAGGTTG SEQ ID GGGGTTGGGGTGTACTAGTTACACATCTTCAACAGACCCCCTCTAGAAATTTTTCAGATGCT NO: TCTGGGAGACACCCAAAGGGTGAAGCTATTTATCTGTAGTAAACTATTTATCTGTGTTTTTG 2428 AAATATTAAACCCTGGATCAGTCCTTTGATCAGTATAAT CD44 ADXCRAD_CN347079_s_at TCAACAGTCGAAGAAGGTGTGGGCAGAAGAAAAAGCTAGTGATCAACAGTGGCAATGGAGCT SEQ ID GTGGAGGACAGAAAGCCAAGTGGACTCAACGGAGAGGCCAGCAAGTCTCAGGAAATGGTGCA NO: TTTGGTGAACAAGGAGTCGTCAGAAACTCCAGACCAGTTTATGACAGCTGATGAGACAAGGA 1104 ACCTGCAGA CD44 ADXCRAD_CV026388_at AATGCCTTTGATGGACCAATTACCATAACTATTGTTAACCGTGATGGCACCCGCTATGTCCA SEQ ID GAAAGGAGAATACAGAACGAATCCTGAAGACATCT NO: 2327 CD44 ADXCRAD_CV026388_x_at GTATGACACATATTGCTTCAATGCTTCAGCTCCACCTGAAGAAGATTGTACATCAGTCACAG SEQ ID ACCTGCCCAATGCCTTTGATGGACCAATTACCATAACTATTGTTAACCGTGATGGCACCCGC NO: TATGTCCAGAAAGGAGAATACAGAACGAATCCTGAAGACATCTACCCCAGC 2328 CD44 ADXCRIH.1441.C1_at CATCAAGAACAGACAAGGGTGTGTAGCGGTTTACAAATACAGCCATAAAAAAGTCAAACAGG SEQ ID ATCTACATGGCATCATCATTCCCCTTGGCCAATCCT NO: 2235 CD44 ADXCRIH.1441.C1_s_at AATCGGACACCCTGACTGATGAATAAATGCCACAAAGGACTTGCCAAGTGGGAGAAAATATG SEQ ID AGGTTAGAGGATAAAGCCAGTACTCTCTTGTTTGGTCATAAACTTGCCTATCTGGTGATAAG NO: ATTCCAATGATGGGAATCCCTTTAACCTTTTGAGGGACTCCCCAGGCACTTAACTCATCCTA 2236 AATAGCAACTGCATCAAGAACAGACAAGGGTGTGTAGCGGTTTACAAATACAGCCATAAAAA AGTCAAACAGGATCTACATGGCATCA CD44 ADXCRIH.1441.C2_s_at ATGGTCCATTCACCTTTATGTTATAGATATGTCTTTGTGTAAATCATTTGTTTTGAGTTTTC SEQ ID AAAGAATAGCCCATTGTTCATTCTTGTGCTGTACAATGACCACTGTTATTGTTACTTTGACT NO: TTTCAGAGCACACCCTTCCTCTGGTTTTTGTATATTTATTGATGGATCAATAATAATGAGGA 2237 AAGCATGATATGTATATTGCTGAGTTGAAA CD44 ADXCRIHRC.1441.C1_s_at GAAGAAGAAAAGCTCCTGACTAAATCAGGGCTGGGCTTAGACAGAGTTGATCTGTAGAATAT SEQ ID CTTTAAAGGAGAGATGTCAACTTTCTGCACTATTCCCAG NO: 1379 CD44 ADXCRPD.11577.C1_s_at AAACAGCATTGCTTTCTGAAATTAGGGCCCAATTAATAATCAGCAAGAATTTGATCGTTCCA SEQ ID GTTCCCACTTGGAGGCCTTTCATCCCTCGGGTGTGCTATGGATGGCTTCTAACAAAAACTAC NO: ACATATGTATTCCTGATCGCCAACCTTT 1527 CD44 ADXCRSS.Hs#S1228681_at TGCATTCCATTCCTTGTGTCTTAAAAGCAGACTGCAGTGTAGCTGAAGCAACCTTCTATTCA SEQ ID TGCCAAAGTGCTTTATTCTGTGACTATACCTTGTATTGAGCTCTAAAACCTCAGAGAGCTTT NO: AAACTGGTTTTGCCTTTATAGAAAGGTTAAGTCCATTTGTGCATTACAGCTTTTATTCTGTG 2068 TGTGTGTGCATACTTAAATTAAAATGGAAATTTATTTGTTAGGTTAGTTTCTCCCAGAATTG CTCCTGGCAAAGAG CD44 ADXCRSS.Hs#S3898008_at GTGAAACCAAAAGAACGCAGGCAAGAAACAGAACAGGAGGGGGAGGGCGACTAAAACATACA SEQ ID CTACCAGGGGAAGAAGAAAAAGTGGCCGCAGCCCCAGGAGGAAAATAAAGAAAAGGAACCCA NO: CCACCTAGAAGACAGACATAATAAAAAAGAACACGCCGAGCATGCACGCGTCAAAAACAAAA 2222 GAAGAAGGAGAAAACAAGCACCGCACGAGGTGAAGTCATTTGTGAAGGAAACGCACAACACA ATATGTGCGGGGAGGAAAAATAAGAGCGATACCACCCTCACG CD59 ADXCRAD_BP343697_s_at TGCTAACTCCTAGCTGACTCAGCATAGATTGTATAAAATACCTTTGTAACGGCTCTTAGCAC SEQ ID ACTCACAGATGTTTGAGGCTTTCAGAAGCTCTTCTAAAAAATGATACACACCTTTCACAAGG NO: GCAAACTTTTTCCTTTTCCCTGTGTATTCTAGTGAATGAATCTCAAGATTCAGTAGACCTAA 2355 TGACATTTGTATTTTATGATCTTGGCTGTATTTAATGGCATAGGCTGACTTTTGCAGATGGA GGAATTTCTTGATTAA CD59 ADXCRD_BP396775_s_at CCTCGTGGGTTTATTATTACCTCATAGGGACTTTGCCTCCTGACAGCAGTTTATGGGTGTTC SEQ ID ATTGTGGCACTTGAGTTTTCTTGCATGCTTGTTAGAGAAACCAAGTTTGTCATCAACTTCTT NO: ATTTAACCCCCTGGCTATAACTTCATGGATTATGTTATAATTAAGCCATCCAGAGTAAAATC 1004 TGTTTAGATTATCTTGGAGTAAGGGGGAAAAAATCTGTAATTTTTTCTCCTCAACTAG CD59 ADXCRAD_CN431378_s_at GATAGCAGGGCATGAAAACTTAGAGAGGTACAAGTGGCTGAAAATCGAGTTTTTCCTCTGTC SEQ ID TTTAAATTTTATATGGGCTTTGTTATCTTCCACTGGAAAAGTGTAATAGCATACATC NO: 2354 CD59 ADXCRAD_CX784253_s_at GAGCTAACGTACTACTGCTGCAAGAAGGACCTGTGTAACTTTAACGAACAGCTTGAAAATGG SEQ ID TGGGACATCCTTATCAGAGAAAACAGTTCTTCTGCTGGTGACTCCATTTCTGGCAGCAGCCT NO: GGAGCCTTCATCCCTAAGTCAACACCAGGAGAGCTTCTCCCAAACTCCCCGTTCCTGCGTAG 2353 TCCGCTTTCTCTTGCTGCCACATTCTAAAGGCTT CD59 ADXCRPD.15392.C1_at GGGCTATTGAGAGTCAGCACCAGCACTGATCATATATAGGATCAGCCTACTGGGGTTGGCCA SEQ ID CGTTGTATGTAGCTGCGAATAGCAAGGAGGGGAACAGCAACATCCCTAGGGAAACCGATCAC NO: AGAAAGGCAGCTCACTACCCCACAGTAAAAAGAACCTTGAGTTTCCCAGTTCAGTCCCCTGC 1745 TGGGTGCATGCTACCCCCCTCCTCTCCCAGAGGCTCTGGACCTACACAGCTGCTGAAAAAGA GAAAATGTCCTTACCTACAATGAACCATCACAGGCACCCA CD59 ADXCRPD.18131.C1_s_at GGCAAGCTCTTCACTATGACAGTAAAGGCTCTCTGCCTGCTGCCAAAGCCTGTGACTTTCTA SEQ ID ACCTGGCCTCACGCTGGGTAAGCTTAAGGTAGAGGTGCAGGATTAGCAAGCCCACCTGGCTA NO: CCAGGCCGACAGCTACATCCTCCAACTGAACCTGATCAACGAAGAGGGATTCATGTGTCTGT 1883 CTCAGTTGGTTCCAAATGAAACCAGGGAGCAGG CD59 ADXCRPD.5301.C1_s_at AACCCACTGGTGCAAGTCCTAGATTCCAAAGGCTGAAGAACCTGGAGTCTGATGTCCAAGAG SEQ ID CAGGAAGAGTGGAAGAAAGCCAGAAGACTCAGCAAACAAGGTAGACAGTGTCTACCACCACA NO: GTGGCCATACCAAAGAGGCTACCGATTCCTTCCTGCTACCTGGATCCCTGAAGTTGCCCTGG 1692 TCTCTGCACCTTCTAAACCTAGTTCTTAAGAGCTTTCCATTACATGAGCTGTCTCAAAGCCC TCCAATAAA CD59 ADXCRPDRC.15392.C1_at ATCTTTCCCCTTGCGGTACTAATCTATTGGCGCACAAGGAGGGCGTCACAGTGCT SEQ ID NO: 2011 CD59 ADXCRPDRC.15392.C1_s_at GTAGTGAGCTGCCTTTCTGTGATCGGTTTCCCTAGGGATGTTGCTGTTCCCCTCCTTGCTAT SEQ ID TCGCAGCTACATACAACGTGGCCAACCCCAGTAGGCTGATCCTATATATGATCAGTGCTGGT NO: GCTGACTCTCAATAGCCCCAC 2012 CDH11 ADXCRAD_BG435621_at ACAAACTAGTGGTGGGGGCACAGCAGAGCCCACGAAAAGAAGTTTTGT SEQ ID NO: 2458 CDH11 ADXCRAD_CX866982_s_at GGGTCCCTGAGCTCCCTAGAGTCGGCCACCACAGATTCAGACTTGGACTATGATTATCTACA SEQ ID GAACTGGGGACCTCGTTTTAAGAAACTAGCAGATTTGTATGGTTCCAAAGACACTTTTGATG NO: ACGATTCTAACAATAACGATACAAATTTGGCCTTAAGAACTGTGTCTGGCGTTCTCAAGAAT 2709 CTAGAA CDH11 ADXCRAG_D21254_s_at TTGTTACTGCTGATTCTTGTAAATCTTTTTGCTTCTACTTTCATCTTAAACTAATACGTGCC SEQ ID AGATATAACTGTCTTGTTTCAGTGAGAGACGCCCTATTTCTATGTC NO: 986 CENPF ADXCRAD_AU132621_at TCTTTCTCTTACAATCTGTTTTAGACATCTTTGCTTATGAAACCTGTACATATGTGTGTGTG SEQ ID GGTATGTGTTTATTTCCAGTGAGGGCTGCAGGCTTCCTAGAGGTGTGCTATACCATGCGTCT NO: GTCGTTGTGCTTTTTTCTGTTTTTAGACCAATTTTTTACAGTTCTTTGGTAAGCATTGTCGT 2490 ATCTGGTGATGGATTAACATATAGCCTTTGTTTTCTAATAAAATAGTCGCCTTCGTTTTCTG TAAGA CENPF ADXCRAG_AF118076_at TATGCCATATATAATATCCCAGAGGGATCTGCTATAATATTGCATAATCGAATTCATATTTC SEQ ID TGCAGCAAAATGTGTGGATACTCTCACAAGGCAGGATAAATAGAGACTATATATACTGGGCC NO: AGGTG 859 CENPF ADXCRAG_AF118076_x_at TGATGCCATATCAGATGGTTTTAGAATTCTGCACTTTAATAATGTAATGCATATGCCATATA SEQ ID TAATATCCCAGAGGGATCTGCTATAATATTGCATAATCGAATTCATATTTCTGCAGCAAAAT NO: GTGTGGATACTCTCACAAGGCAGGATAAATAGAGACTATATATACTGGGCCAGGTG 860 CENPF ADXCRPD.1656.C1_s_at GAAGGCACTTTGTGTGTCAGTACCCCTGGGAGGTGCCAGTCATTGAATAGATAAGGCTGTGC SEQ ID CTACAGGACTTCTCTTTAGTCAGGGCATGCTTTATTAGTGAGGAGAAAACAATTCCTTAGAA NO: GTCTTAAATATATTGTACTCTTTAGATCTCCCATGTGTAGGTATTGAAA 1464 CENPF ADXCRPD.17056.C1_at TCATCCTCTTGTGTGCCTGACAGCTCTAGTCTTAGCAGTTTGGGAGACTCCTCCTTTTACAG SEQ ID AGCTCTTTTAGAACAGACAGGAGATATGTCTCTTTTGAGTAATTTAGAAGGGGCTGTTTCAG NO: CAAACCAGTGCAGTGTAGATGAAGTATTTTGCAGCAGTCTGCAGGAGGAGAATCTGACCAGG 1788 AAAGAAATCCCTTCGGCCCCAGCGAAGGGTGTTGAAGAGCTTGAGTCCCTCTGTGAGGTGTA CCGGCAGTCCCTCGAGAAGCTAGAAGA CNN3 ADXCRIH.2427.C1_s_at GCATTTGTGATTATATGTGTACTCATTCTCTTACCTAGCGAACAAGATCTTTTCAAAGTGGT SEQ ID GTTTCTAAAAGAGCATGTACAAAAGTGGCCTGTGGACATTTAGGCCTGGGTGATGCATTTGC NO: TCTTCCTGTTTGTGCCAATGTATCAATGTAAAGTTGCTCTGTTTTCTTCAACTGTATTTATT 1157 GCTGCATTTCTCAGCATAAACTTATCCCATTGT CNN3 ADXCRPD.1098.C1_s_at AAGAGCAAATGCATCACCCAGGCCTAAATGTCCACAGGCCACTTTTGTACATGCTCTTTTAG SEQ ID AAACACCACTCTGAAAAGATCTTGTTCGCTAGGTAAGAGAATGAGTACACATATAATCACAA NO: ATGCACACTGATCATGACTTTATTTAAAAATTAGCAAACAATACTGTAGAAACATTGATATG 1847 TAAATTTCTAAAATGCTGCATCTTAAATTTAGTTGGCAAAGACCACATTTAGCAATAAGCAT GAGTTTAGTCTTCCATGTAGAAACCAGATA CNN3 ADXCRPD.2332.C1_at CATATCAAATGGTTTCTAACAGGTATTGGTTTGCCTAATTTTCAAAACAAACCTCCTTGATC SEQ ID CACGGGGGCCCTTTTGATGAATTACAATGGGGGAACCTCCATTTCCCCTTTACCCGACGGCG NO: GAACACCACAATTCTTTTTTCCCCAAGCGGGGTTGCTCTCTCTTTACCAAGCAATCCTTTGG 1476 TTACCCAATCACCGTGTGCGCCTTGTGTGGTAACACTTTTTCAACGCGCCCTCATGCGGAGA CGAAATCGCACTCTCTTTGCG CRIM1 ADXCRAD_AI651806_s_at ACATTTTCTTTTCACGTTAAGCATACTGGGTATCTGTGTCTTTCACAACAAGCATTTTTAAA SEQ ID AGAAAACTCAATGCACAAATGGGTTAATTAGTATAAAAGTGCTAAGGGCTGTTTGAAAAGTT NO: ACCACTATAGTATACAGTCAGTTATATTTGAGGCATACTACAACAAACTTCCAGCTTATTGT 2454 GGACAATATTCCAGTAGTTGTTTCAAACCATTGTTTGAAAAAAAAAAAAAAAAAATCCAGGA GCTGATTAGTGATGCAG CRIM1 ADXCRAD_BC016339_s_at AAGAATCTTCACTTGGGTGCAGCCTGTTATCTCTGTAATCTACCTGGAGGTGACCCATATCT SEQ ID AGGAGAAAAAAAATTATAAGCATTTATTACCTAAACCAGAATTGTTAAGGATTATTTTAATG NO: ACATTGCAAATAGAGATCAGCAACTTGGTTTTATTGCTTCCCAGTTTTTTGAGGCTAAAAAT 2786 GTGATTAAAATCTAATGTTGATCCAAAGAGCTCTTAGTAGAGAGCAGAGCGCTTA CRIM1 ADXCRAD_BG621095_s_at AAAAAATTGTAGATGCTTGCTTTTTGTTTTTTCAATCATGGCCATATTATGAAAATACTAAC SEQ ID AGGATATAGGACAAGGTGTAAATTTTTTTATTATTATTTTAACAGATATGATTTATCCTGAG NO: TGCTGTATCTATTACTCTTTTACTTTGGTTCCTGTTGTGCTCTTGTAAAAAGAAAAATATAA 1128 ATTTCCTGAAGAATAAAATAGATATATGGCACTTGGAGTGCATCATAGTTCTACAGTTTGTT T CRIM1 ADXCRAD_C16716_s_at CTTCTAGCCGTCAAACTCTGATCGACTTACACTTAAGACTGTGTCTTTGGTAGCCTACCCTA SEQ ID TTCCACTTTTATTACAAAGGCAGCTCTTAAGACATAAATCCATCTCTTCAGGCTCGAACTGC NO: AAAACACACGTCGAGAGGTGACAATGTTGGGACTGTCAAAAAGAACTTAAAGAGTGGGATAA 2751 CCAGCCGGGC CRIM1 ADXCRAD_CD101810_at AAATAGAATTGACCTCCAGCCCGGATTAGGCATAAATTTTG SEQ ID NO: 2396 CRIM1 ADXCRAD_CD101810_x_at GGTGTTCTACCTGTTTGCATCAAAGGAAAAAAAGATTTTTTTTCCAAGGGCCAATTTTTTTA SEQ ID TCTTTTCCCAAAAAAAATTTGTTAATGGAACATTTACAAAAATAGAATTGACCTCCAGCCCG NO: GATTAGGCATAAATTTTGGTTGGGA 2397 CRIM1 ADXCRAD_AA642418_s_at GACTTATACTCATGAGGTCTACCTACAGTCCATTCCCATTTAGGGGAAGAGAAAGGAGAGGA SEQ ID AATGGCCAAGAAGTCCATAAGAAGTGGACAGTGCTTTAACTTTTTCAAGTTTTGCTAACATA NO: TTTTATGTAAGTTATTCAATACCCCCATATTAAAGAGCAGCAGCTATTAAACACCAACATTT 2873 ATTAGCTGCTGGAAAGTAATAAATAACTTCAGCTAGTCCCCTTCAGTTTCCATAAAATTATA AAACCAACCATTTGACGTGAAAAAGCAGTTT CRIM1 ADXCRAG_AC007401_at GGGCAGAAAAGCCATGTCGCCATTTACTTGACACCTTTCAGTGCCACACACACCCTTCTGCC SEQ ID CCTCCCCTGCCTAGTCCAGGGCTTCACACTGAGCCTTCCTATGACAATAGGGGCCGAACTGC NO: CACTGGTTTCTGAGGCCTCAGTGTAAAGGGCAAATGCGACACCAATTCCAACAAACCTGTAA 842 ATGTCAATGGCTAAGTAGTAAAAGTTTCTGCAGAGGCCCCAGAGCTGGGATTGATTCAGTTC CACCTCAGGTTTTTTCCTGAGTGAGAGGGAGAGACGTAACTTTGGAAT CRIM1 ADXCRAG_AF168681_x_at ACTAATGATAATCCATCTCCCTTCGCTGACTCTCTTTTCGGACTCAGCCCGCCTGCATCCAG SEQ ID GTGAAATAAACAGCCGTGTTGCTCACACAAAGCCTGTTTGGTGGTCTCTTCACACGGACGCA NO: CATGAAATTTGGTGCCGTGACTCGGATCGGGGGACCTCCCTTGGGAGATCAATCCCCCTGTC 869 CTCCTGCTCTTTGCTCCATGAGAAAGATCCACCTACGACCTCAGGTCCTCAGACCGACCAGC CCAAAAAACAT CRIM1 ADXCRPD.11873.C1_at GTCCCTACTGCATAGAAGACACAATTCCAAAGAAGGTGGTGTGCCACTTCAGTGGGAAGGCC SEQ ID TATGCCGACGAGGAGCGGTGGGACCCTTGACAGCTGCACCCACTGCTACTGCCTGCAGGGCC NO: AGACCCTCTGCTCGACCGTCAGCTGCCCCCCTCTGCCTGTGTTAGCCCATCAACGTGGAAGG 1583 AAGTTGCTGCCCATGCGTCCATGTAAGG CRIM1 ADXCRPD.11873.C1_s_at TGCATTGATAGCGTAATTAGCTGTTTCTCTGAGTCCTGCCCTTCTGCATCCTGTGAAAGACC SEQ ID TGTCTTGAGAAAAGGCCAGTGATGTCCCTACTGCATAGAAGACACAATTCCAAAGAAGGTGG NO: TGTGCCACTTCAGTGGGAAGGCCTATGCCGACGAGGAGCGGTGGGACCCTTGACAGCTGCAC 1584 CCACTGCTACTGCCTGCAGGGCCAGACCCTCTGCTCGACCGTCAGCTGCCCCCCTCTGCCTG TGTTAGCCCATCAACGTGGAAGGAAGTTGCTGCCCA CRIM1 ADXCRPD.15616.C1_at ACAGATGTCACAGCCGTGCTTATTCTTCAGCAATCCAAGTGGACAATACTTGTCACAGATTA SEQ ID TGGGTCTGCACTTCTTGGGCCTTGGGCGGCACTCACAGATCTCACAGTTTTGGGCATCAGTA NO: AGGAAACCGAAGGGACAGTTCAAGGTGCAGCCTTGTTTACGTTCTGAACATAGTTCCTCGGT 1774 GTTTATGCACTCACAGGTCCGACAACCATTGTGATCGCGTTTGAAACCATTAATGCAGTCCT TCCCTGTCAGAGGCAGTTTGATACGGTCCCGAC CRIM1 ADXCRPDRC.15616.C1_s_at AGTGCAGACCCATAATCTGTGACAAGTATTGTCCACTTGGATTGCTGAAGAATAAGCACGGC SEQ ID TGTGACATCTGTCGCTGTAAGAAATGTCCAGAGCTCTCATGCAGTAAGATCTGCCCCTTGGG NO: TTTCCAGCAGGACAGTCACGGCTGTCTTATCTGCAAGTGCAGAGAGGCCTCTGCTTCAGCTG 2018 NGCCACCCATCCTGTCGGACACTTGTCTCACCGTGGATGGTCATCATCATAAAAATGAGGAG AGCTGGCACGATGNGTGCCGNGAATGCTACTGTCTCAATGGACGGG CRIM1 ADXCRSS.Hs#S1805720_s_at GAAGATGTTTGTCTGAGCATCCCATGAGGTAAGCAGCCCCATGGAAGGACCAGCTGCATCCA SEQ ID GCAAAGGGCTCCAGGTCCCTGACGTAGTTGACGGTGATGGCAGAAGTAAATCTTTGTATTCT NO: TGCAGAGACTTTGTTTTTCTGTCATTCCACAGCAGCTCAGCATACTCTAATAAACGTCCTCC 2065 TCTTCCCCTTCGTAGCATTCTGGGACTAATCAGGGTTTCATCTGCTCACATATTGTAGCGAT GGGTTC CTNNAL1 ADXCRPD.129.C1_at GACAGACACACTGGGAGTCGTGCTGCGCACCCCCCCTATTATTTTCGCGCACCCAATTTAAA SEQ ID GAGGTGGGCCGGCCGCGCCCACCCGTCCATCACCTCGATATGCACACTACCTCCGCCGTCGG NO: GGCCCTCGCGGCCCGCCATGCTGTTCGCAAACACTCACCGCCCGGCCGCGGGTCCGCGATGC 1484 TGCGCGTGTGTGAGAAGTATGGTGAGCGCGATATGGCGGCAACACCACTGTCGACTTGTCTC G CYR61 ADXCRIH.1579_C1_at TACCTAATATCTGAGTGTATGCCATTCGGTATTTTTAGAGGTGCTCCAAAGTCATTAGGAAC SEQ ID AACCTAGCTCACGTACTCAATTATTCAAACAGGACTTATTGGGATACAGCAGTGAATTAAGC NO: TATTAAAATAAGATAATGATTGCTTTTATACCTTCAGTAGAGAAAAGTCTTTGCATATAAAG 1207 TAATGTTTAAAAAACATGTATTGAACACGACATTGTATGAAGCACAA CYR61 ADXCRPD.10589.C1_at GGAACCGCATCTTCACAGTCCTGGTCAGCTGGGGCGTGCAGCATCGGCCGTCCACGCAGGAA SEQ ID CCGCAGTACTTGGGCCGGTATTTCTTCACACTCAAACATCCAGCGTAAGTAAACCTGACTGG NO: GTTCGGGGGATATCTTGGTACTTGCTGCATTTCTTGCCCTTCTGTAAGAGAAAGGCGAGAAG 1443 GCAAGTTAGGGGTGATATTTCTCTTTCTTCAAAAAGATGTTCACATCCCAACCACCTGCCAG GCAACAGTCTACACGTCCCTTAAGGAACTTACTTTCAGGCTGCTGT DKK1 ADXCRAG_AF177394_s_at GTTATCTTGACTGACAAATATTCTATATTGAACTGAAGTAAATCATTTCAGCTTATAGTTCT SEQ ID TAAAAGCATAACCCTTTACCCCATTTAATTCTAGAGTCTAGAACGCAAGGATCTCTTGGAAT NO: GACAAATGATAGGTACCTAAAATGTAACATGAAAATACTAGCTTATTTTCTGAAATGTACTA 870 TCTTAATGCTTAAATTATATTTCCCTTTAGGCTGTGATAGTTTTTG DNAJB6 ADXCRAD_BQ222360_at GGAAAAGGAGTGGTATTTGAATGCTTTCTGTGGGACAATGTACCCCCTAAACACATCATGTA SEQ ID TTTTTAAATTGCCACCCTACCTAAAATAAAACCATAAGCCATATTTGAAA NO: 2717 DNAJB6 ADXCRAD_BQ222360_s_at AAAATGCCAGCAATTTTAATCTAGCAGTGTTGAAGCTGGGAATTTTTTGGCGCAATCCATGT SEQ ID AGCAGTGACCCAGGCTTGGGAGCCAGAAACAAGTGTGACCT NO: 2718 DNAJB6 ADXCRIH.476.C2_at TTGTGTCTGAAATGTGAGCCACGTAGTGTCGGCCTGCTGTGAAGTTAACATTGCCAGGACGA SEQ ID TTCTTCTACAGAAATAATTTCAATTTTTTTCAGTATTTAGTAGTGAAAGATATTAATACATT NO: AATGGTAATACATTTCTGGTTTAATATAAATTAAGGATGTTTTCTAGTTGTGCATGAATGCT 1281 GGCAACTTAGTAAGTTTTGACAATTGTTTAAATATGTAATGTTAAGCTTAGGTTTAAAAAAG TAAAGCTGGTAAACTGGGTCTTTGTCATTTG DNAJB6 ADXCRPD.14111.C1_at GAGTGTGGCCTCGAGACAGTCCTGACCGACGCTGCTACCTAGCGCGTGTGCACGACCGCATG SEQ ID CCGAGCACGGTGGAGCGCCAGCGTCTGGGGGTGCACCGCGTGCCTCAAGTCCGGTCTAGTGA NO: TTGCCTTTGGTCGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN 1657 NNNNNNTTTCAATCCTGCTGCGGACGCGAGG DNAJB6 ADXCRPDRC.14111.C1_at TGAGTAACATTCATGCAATGAGCACTCAGTGG SEQ ID NO: 1986 DNAJB6 ADXCRPDRC.14111.C1_s_at AGGACTGTCTCGAGGCCACACTCGCTCGGCAGGATTATTCGATCACGGATCAGTCAGAGCAG SEQ ID GGTCAGGAGACGGGGCTGACGGCACGGGTGGCGGGGACAGACGTTTGGGACTTGGCCGCGAC NO: TCTCTGCTTCTCTCCAGCTCTCAATCTGCTGCATTTTCCTCTAGTGCTTCCGGATCCTCTTC 1987 ATTCTTTTCGGCATACTCAACCACTCCGCATGCTGCTGGAATATTTCTGGCTTTAGAAGTAC AGGAGGCGCAGATGGCTAACTGAGTAACATTCATG DNAJB6 ADXCRSS.Hs#S1921365_at GAAACAGTCTCGTACATCACGGTTCATTTTTAACCTTTTTTCTTAAATTTTAGAGATGGCAT SEQ ID CTCATTATTTTTCCCCAAGCTGGACTCGAACTCCTGGGCTCAAGGAATCTCCTACCTCAGCC NO: TCCCCAGTAGCTGGCATTACAGGGGTACACCACCATGCCTGGCTTAGTATGTGATGTTTTTA 2100 TGTGTATTTAAAAAAGACTCCTTAACTTCTTCTAAGTGACCTGTGTGTAGGTGTGCCTGTGT ATGAACTCTGTCCAA DNAJB6 RDCR166_G12_at TCTGGGGTGTTTTGCGCGTGTGTAAATACCGGCCCGTTTTTCTCCAGCATGGCCCCTAATCC SEQ ID ATGGGACACTAGGGAGGGGTGCCCTGAGCAAAAATTTTTTGGCTAAAATAATTAGCTAAATC NO: CCATGTAAAAATTAT 1360 DNAJB6 RDCR166_G12_s_at TGGGCGCATCTAGTTAGAATGAAGTGACTTTCGTAAGGAGTCAATGTTCGCGAACTGAAACA SEQ ID TGAGTTCAACCTCCTTGTGCCGGCCTCTGGGGTGTTTTGCGCGTGTGTAAATACCGGCCCGT NO: TTTTCTCCAGCATGGCCCCTAATCCATGGGACACTAGGGAGGGGTGCCCTGAGCAAAAATTT 1361 TTTGGCTAAAATAATTAGCTAAATCCCATGTAAAAATTATGGAATCTAGCAAAACCTACACC ATATTT EMP3 ADXCRPD.3976.C1_s_at TTGCACCAGCGTGGCGGTGTTTACTGGCGCCTTGATCTATGCCATTCACGCCGAGGAGATCC SEQ ID TGGAGAAGCACCCGCGAGGGGGCAGCTTCGGATACTGCTTCGCCCTGGCCTGGGTGGCCTTC NO: CCCCTCGCCCTGGTCAGCGGCATCATCTACATCCACCTACGGAAGCGGGAGTGAGC 1915 F3 ADXCRAD_BU941055_at GGAATTGTTACTGGTGTACTTATTCTATCTTCCATTTTATTATTTATGTACAATTTTGGTGT SEQ ID TTGTATTA NO: 2425 F3 ADXCRAD_BU941055_x_at GGAATTGTTACTGGTGTACTTATTCTATCTTCCATTTTATTATTTATGTACAATTTTGGTGT SEQ ID TTGTATTAGCTC NO: 2426 FAM50A ADXCRPD.13832.C1_s_at AATCCAACATTGACAAGAAGTTCTCTGCGCACTACGACGCGGTGGAGGCAGAGCTCAAGTCC SEQ ID AGCACCGTGGGTCTCGTGACCCTGAATGA NO: 1708 FAM50A ADXCRPD.6370.C1_at TGGGACAAGTACACGATCCGCTGAGCATCCAGGAGGCTGCGCGGCCCCGGCTCCTCAGCTCC SEQ ID CTCAGTGTGCCCCGTGGTGTCACCGGGACTCCAGGCACCCGCTCCCCTGCGACCATGCCAGG NO: CACGCTGGGAGGAGGACGGCAGCTGCTCGTGTCCTGCCCCTGCCACATCAGTGACTGCTTTA 1743 TTCTTTTCCAATAAAGAAGTGCACGTGTCAGAGCTGGAGCGCCTGCATTGTGAGAAACCAA FAM50A ADXCRPD.6370.C1_x_at GACAAGTACACGATCCGCTGAGCATCCAGGAGGCTGCGCGGCCCCGGCTCCTCAGCTCCCTC SEQ ID AGTGTGCCCCGTGGTGTCACCGGGACTCCAGGCACCCGCTCCCCTGCGACCATGCCAGGCAC NO: GCTGGGAGGAGGACGGCAGCTGCTCGTGTCCTGCCCCTGCCACATCAGTGACTGCTTTATTC 1744 TTTTCCAATAAAGAAGTGCACGTGTCAGAGCTGGAGCGCCTGCATTGTGAGAAACCAA FAM50A ADXCRPDRC.6370.C1_at ACTGCTGCATGGTGTTGCCCTTTCTCATCTTGACTGTCCGCCGGTGCCCAGAGCCATCCCAG SEQ ID TAGCTGAAGGTGATCTCGATCTCCTCACTCTTGATCTTCTCCTGCTTGGCTTCCCACTCCTG NO: CCGCAGCTCTTCCCGAAGCCGATTCTCCTCCTCCTCACGGTCTCGATCAGGCAAGAAGCTTG 2010 TGTCAACGTCTGGGT FHL1 ADXCRAD_BP325154_s_at GTGATTCCTAGGACTTTTCCTCAAGAGGAAATCTGGATTTCCACCTACCGCTTACCTGAAAT SEQ ID GCAGGATCACCTACTTACTGTATTCTACATTATTATATGACATAGTATAATGAGACAATATC NO: AAAAGTAAACATGTAATGACAATACATACTAACATTCTTGTAGGAGTGGTTAGAGAAGCTGA 1850 TGCCTCATTTCTACATTCTGTCATTAGCTATTATCATCTAACGTTTCAGTGTATCCTTACAG AAATAAAGCAGCA FHL1 ADXCRAD_BP361024_at GACTGTGTCAAGAGTGAGCCACCCAGTCTCTAAAGCTAGGAAGCCCCCAGTGTGCCACGGGA SEQ ID AACGCTTGCCTCTCACCCTGTTTCCCAGCGCCAACCTCCGGGGCAGGCATCCGGGTGGAGAG NO: AGGACTTGTCCCTCGTGGGTGGTGGTTCTTTATAGAA 2502 FHL1 ADXCRAD_CX872156_s_at CACTTACCAGGATCAGCCCTGGCATGCCGATTGCTTTGTGTGTGTTACCTGCTCTAAGAAGC SEQ ID TGGCTGGGCAGCGTTTCACCGCTGTGGAGGACCAGTATTACTGCGTGGATTGCTACAAGAAC NO: TTTGTGGCCAAGAAGTGTGCTGGATGCAAGAACCCCATCACTGGG 2369 FHL1 ADXCRPD.10038.C1_at TGCAGAAGAGTCAATCTACCTAAGTTTTCATTTTTAAATTGCAGCCGGACAGAAATTCACTT SEQ ID TGCTGCAGGGTTGCTTTTTGCTAAATGCTAATATGATCACTGTGTGCCCTTATTTGAGTAAT NO: ACTGTAAAATGGGAGAAAAGACGGAAGGAGAACTTTAAAGAAGGGAAGGACCACTCTTCCCC 1838 TATTGATGGTATAGGGCAGAAAGTAAGGACACAAAGAACGAGATTCAAATGCCATTTTACAG GACAGGAGCCCCTGTCAGTTTACAGCTTGAGACACGCGACGGGTACCGAG FHL1 ADXCRPD.11024.C1_s_at TGTGCTTTCAAATAACTAACACGAACTTCCAGAAAATTAACATTTGAACTTAGCTGTAATTC SEQ ID TAAACTGACCTTTCCCCGTACTAACGTTTGGTTTCCCCGTGTGGCATGTTTTCTGAGCGTTC NO: CTACTTTAAAGCATGGAACATGCAGGTGATTTGGGAAGTGTAGAAAGACCTGAGAAAACGAG 1409 CCTGTTTCAGAGGAACATCGTCACAACGAATACTTCTGGAAG FHL1 ADXCRPD.16965.C1_at GGGCCCTATGAACAGACCATTCCTGGGGACCGAATACCTTGCTTTCCACCTGCAAAAAAAGT SEQ ID CTCCCTGGGAAATCCTGGCCCAACAAAAGAGCTTTGTTNTTTCCCCCCAGCGAACAAAGGGT NO: ATTTGTCCCTGAATGTGTGCCAAAAAACACGTGTAAACACTAACAAGGAGGCTCTCTTGGAC 1388 CTTCGAAAAAAGGGCAATTGGAAATCTCCGGCCCCTTTTGAGGCCCTTGACTTTCATGGCCC TCATCCCCAGTCGATAAGGG FHL1 ADXCRPDRC.10038.C1_at AGTATTACTCAAATAAGGGCACACAGTGATCATATTAGCATTTAGCAAAAAGCAACCCTGCA SEQ ID GCAAAGTGAATTTCTGTCCGGCTGCAATTTAAAAATGAAAACTTAGGTAGATTGACTCTTCT NO: GCATGTTTCTCATAGAGCAGAAAAGTGCTAATCATTTAGCCACTTAGTGATGTAAGCAAGAA 2035 GCATAGGAGATAAAACCCCCACTGAGATGCCTCTCATGCCTCAGCTGGGACCCAGCTTGAGA CCCGCGA FHL1 ADXCRSS.Hs#S3747393_at TGCAGCTCCCTTTGCCAAGGCATTTCCTATAGAATCCTGCCACCCAAAAGGTACCAAATATG SEQ ID AGTTTCTATTAGCTTTCAACTTCTTTAAACATATGCTAATTTGTTCCTCTCCCCCGAAAAAG NO: AGATTTGCACGGGTAAATAGATAGCAATTATTTCATTTGTGCAGGAAATACAAGAATTGAGA 2193 CTACTTTCTAAAACTATCCACAAACATGGTTATTGTGCTAGCAAACTTCCAGCGTAATTTAG AGAGAAAGAATGAGAGAAAATAAATGAGCAGTTGCCTGGTACTCAC FHL2 ADXCRIH.1926.C1_at TTGTGATAGTTCAGTCCCAGGGAAAGAGAAAACTCGCCCTAGGCCCTAGGTGGGAAGATGGT SEQ ID TTGAAATTTTTGTAATCGAGTAAGGCACACCCAAATGTAAAAATCCTTTTGAATGATGCCTT NO: TATAAATCTTTCTCTCACTGTCTATTTAAGTGCAATTAACATATGTCACGAACTTGAAAGTT 2240 TTCTAAACTCAATAAGGTAATGACCAGTTGTTATTTACAGCTCTGTAACCTCCCGTTGCGTC AAGTCTAAACCAAGATTATGTGAC FHL2 ADXCRIH.1926.C1_s_at CGCCCTAGGCCCTAGGTGGGAAGATGGTTTGAAATTTTTGTAATCGAGTAAGGCACACCCAA SEQ ID ATGTAAAAATCCTTTTGAATGATGCCTTTATAAATCTTTCTCTCACTGTCTATTTAAGTGCA NO: ATTAACATATGTCACGAACTTGAAAGTTTTCTAAACTCAATAAGGTAATGACCAGTTGTTAT 2241 TTACAGCTCTGTAACCTCCCGTTGCGTCAAGTCTAAACCAAGATTATGTGACTTGCAATAAA GTTATTCAGA FHL2 ADXCRIH.1926.C2_at CGCTTCACAGCTCGCGATGACTTTGCCTACTGCCTGAACTGCTTCTGTGACTTGTATGCCAA SEQ ID GAAGTGTGCTGGGTGCACCAACCCCATCAGCGGACTTGGTGGCACAAAATACATCTCCTTTG NO: AGGAACGGCAGTGGGCATAACGACTGCTTTAACTGTAAGAAGTGCTCCCTCTCACTGGTGGG 2242 GCGTGGCTTCCTCACAGAGAGGGACGACATCCTTGTGCCCCGACTGTGGGAAAGACATCTGA ATCAACACAGAGAAGTTGCTGCTTGTGATCTCCCACACGAATTTTTATGTT FHL2 ADXCRIH.1926.C2_s_at TCAGCGGACTTGGTGGCACAAAATACATCTCCTTTGAGGAACGGCAGTGGGCATAACGACTG SEQ ID CTTTAACTGTAAGAAGTGCTCCCTCTCACTGGTGGGGCGTGGCTTCCTCACAGAGAGGGACG NO: ACATCCTTGTGCCCCGACTGTGGGAAAGACATCTGAA 2243 FKBP9 ADXCRAD_CD251162_s_at GCAGAGGCCAGCTGCCGCAAGACAGCAATGACAGTCCACCTGCCGACCTGATTCCTGCATCA SEQ ID TGGAATAACCACATGGCTACCTTCTATCCTCTGTTCCCAAATGGTGGTGGCACTTATCCTGA NO: AGTCGTCAATGATTTCCCTTTGAAACTACTTTATTTTACTAATTTAAACTATTTTGTACTGA 923 TGTAGCCCTGAGGTAGTTCATGAAAATGCTGTGCACTCATTCCATGGAATAAATGTTGGAAA GCTGATCTTTTCTGATATAA FKBP9 ADXCRPD.16135.C1_at GGGCCATCATCAGAATTTGCACAGGCTGCTGGGAAGAGCCATGGCTGTCTGCTGGGAACTCT SEQ ID GCTGGGGCAAGCAAGCCCTTTGACTCTCCTGCCCATCTCAAGAATATTT NO: 1762 FKBP9 ADXCRPD.16135.C1_x_at GGGCCATCATCAGAATTTGCACAGGCTGCTGGGAAGAGCCATGGCTGTCTGCTGGGAACTCT SEQ ID GCTGGGGCAAGCAAGCCCTTTGACTCTCCTGCCCATCTCAAGAATATTTCTAA NO: 1763 FKBP9 ADXCRPD.3075.C1_s_at AGAAGTTTGGGCTGATCGCCAGTGATAGTAAACAAAATCTGTGCAGAGGGCCTTAGCATGGG SEQ ID ATGTGTCCAGTATTGAAAAGGCTGCACTGCCAACCATGATTTGTGAGCCTTCTGGGAAATTT NO: TGTTATTAAAGGAATATATAGTGTCAGACGGAAGTTATAATCATCTTGGAGGAACCATAAGA 1918 AAAGGTGTCCAGGGTATCTATATAAA FLNA ADXCRAD_CN332899_at TGACCTCTCGGCTTTCACTTGGGCAGAGGGAGCCATTTGGTGGCGCTGCTTGTCTTCTTTGG SEQ ID TTCTGGGAGGGGTGAAGGATGGGGGTCCTGTACACAACCACCCA NO: 2347 FLNA ADXCRAD_CN332899_x_at TGACCTCTCGGCTTTCACTTGGGCAGAGGGAGCCATTTGGTGGCGCTGCTTGTCTTCTTTGG SEQ ID TTCTGGGAGGGGTGAAGGATGGGGGTCCTGTACACAACCAC NO: 2348 FLNA ADXCRPD.10169.C1_at TCAGGCAACCTGACGGAGACCTACGTTCAGGACCGTGGCGATGGCATGTACAAAGTGGAGTA SEQ ID CACGCCTTACGAGGAGGGACTGCACTCCGTGGACGTGACCTATGACGGCAGTCCCGTGCCCA NO: GCAGCCCCTTCCAGGTGCCCGTGACCGAGGGCTGCGACCCCTCCCGGGTGCGTGTCCACGGG 1867 CCAGGCATCCAAAGTGGCACCACCAAC FLNA ADXCRPD.13338.C1_at GGTAGGCGTCAATGTCACTTACTGGAGGGGATCCCAGCCCTAAGAGCCCTTTCTCAGTGGCA SEQ ID GTATCTCCAAGCCTGGACCTCAGCAAGATCAAGGTGTCTGGCCTGGGAGAGAAGGTGGACGT NO: TGGCAAAGACCAGGAGTTCACAGTCACAATCAAAGGGTGCTGGTGGTACAAGGCAAAGTGGC 1621 ATCCAAGTATTGTGGGCCCCTCGGGTGCAGCGGTGCCCTGCAAGGTGGAGCCAGGCCTGGGG GCTGACAACAGTGTGGTGCGCTTCCTGCCCCGTGAGGAAGGGCCCTATGA FLNA ADXCRPD.15612.C1_at GCTACACCATTATGGTCCTCTTTGCTGACCAGGCCACGCCCACCAGCCCCATCCGAGTCAAG SEQ ID GTGGAGCCCTCTCATGACGCCAGTAAGGTGAAGGCCGAGGGCCACTGGCACTCAGTCGCACT NO: GGTGTCGAGCTTGGCAAGCCCACCCACTTCACAGTAAATGCCAAAGCTGCTGGCAAAGGCAA 1773 GCTGGACGTCCAGTTCTCAGGACTCACCAAGGGGGATGCAGTGCGAGATGTGGACATCATCG ACCACCATGACAACACCTACACAGTCAAGTACACGCCTGTCCAGT FLNA ADXCRPD.16964.C1_at TGGGCTGTCACTTTTGCTGGCGTCACCCTGTGACTTATCCACGTACACCTCGAAGGGGCTCT SEQ ID TGGCGATGTGCTGGCCAGCAAAGAGCACAGTAACCTTATGAGTCCCCGTCAACTCGGGGACG NO: TACCAGACGGAGAAGGTGCGGTTCTTGTCGTTATTGGCGGTCACTTTTGCCTCCTCCTGGTG 1387 TCCGGCCGGGTCCTCCACGTACACCAGCACCTCTCCCTGGCCAGCACCTCTGGTCTCCACAG TGAACTCTACCCGCTTCTTCACAATGCACGTGATCAAATCCTGTAGAGTC FLNA ADXCRPD.3034.C1_at AGTACAATGAACAGCACGTCCCAGGCAGCCCCTTCACTGCTCGGGTCACAGGTGACGACTCC SEQ ID ATGCGTATGTCCCACCTAAAGGTCGGCTCTGCTGCCGACATCCCCATCAACATCTCAGAGAC NO: GGATCTCAGCCTGCTCGTACGGCCACTGTGGTCCCGCCCTCGGGCCGCGAGGAGCCCTGTCT 1490 GCTGAAGCGGCTGCGCAATGGCCACGTGCGCATTGCATTCGTGCCCAAGGAG FLNA ADXCRPD.3150.C3_at CTCATGGGTCTTGCCCGATGGGCTGGTCACCTGGGCTGTCATATCCTGGATGCTAATTTCAG SEQ ID GGATTTTCAGGCTGAGGTCACAATGACTACCAACGTTGGCCACTGAAGGAGCCCGACGCCTG NO: CGGGTGATGCTCTCTTTCACCCGGCCCTCGCCTGTCACCTTCACAGAGAAGGGGCTGCCAGG 1902 CACGTGCTGGTCGGCAAACTTGATGTTGATGATGTAGTTGCCTGGCTCTGTGGGGCAGTAGG TGACCCTGCACGTCC FLNA ADXCRPD.3227.C1_at TTCACCCTGTCTGGGTGGAAGTCCTGGGGCGCGTCACGGATGTCAGCCATGAAGGGGCTGAG SEQ ID GCGGATGTCTTCGCTGTTGCACAGCACGTGAACGGCATACTCGCCAGCCTCCTGCGGCCAGT NO: AGCGCACATCACAGGAGCCGTCGCCCTTGTCGTCACATTCGATCTTAGCCTGCGATGGCCCT 1542 TCCACCGAGAAGCCCAGCGTGCCCACGTCGTCCCCGATAGCCTCCACCACAAAGTCTGCTGA CTTGCCAACGACG FLNA ADXCRPDRC.16964.C1_at AAAAGTGACCGCCAATAACGACAAGAACCGCACCTTCTCCGTCTGGTACGTCCCCGAGTTGA SEQ ID CGGGGACTCATAAGGTTACTGTGCTCTTTGCTGGCCAGCACATCGCCAAGAGCCCCTTCGAG NO: GTGTACGTGGATAAGTCACAGGGTGACGCCAGCAAAAGTGACAGCCCAAGGTCCCGGCCTGG 2051 AGCCCAGTGGCAACATCGCCAACAAGACCACCTACTTTGAGATCTCCACGGCAGGAGCTGGC AC FLNA ADXCRPDRC.3150.C3_s_at GTCTCGTCAGCAACCACAGCCTCCACGAGACATCATCAGTGTTTGTAGACTCTCTGACCAAG SEQ ID GCCACCTGTGCCCCACAGCATGGGGCCCCGGGTCCTGGGCCTGCTGACGCCAGCAAGGTGGT NO: GGCCAAGGGCCTGGGGCTGAGCAAGGCCTACGTAGGCCAGAAGAGCAGCTTCACAGTAGACT 2048 GCAGCAAAGC FLNA ADXCRPDRC.3227.C1_at AGAAGACAGGTGTGGCCGTCAACAAGCCAGCAGAGTTCACAGTGGATGCCAAGCACGGTGGC SEQ ID AAGGCCCCACTTCGGGTCCAAGTCCAGGACAATGAAGGCTGCCCTGTGGAGGCGTTGGTCAA NO: GGACAACGGCAATGGCACTTACAGCTGCTCCTACGTGCCCAGGAAGCCGGTGAAGCACACAG 1960 CCATGGTGTCCTGGGGAGGCGTCAGCATCCCCAACAGCCCCTTCAGGGTGAATGTGGGAGCT GGCAGACACCCCAACAAGGTCAAAGTAT FOXN3 ADXCRAD_BM995629_s_at CCGTGTAGGTCTATTGGCCAGCCAAGGTCAGACGACCCTAAGCATCAATAGTAAACCTCTTG SEQ ID GTCTTCTGATTGCTTTATCACTTTTTTTTTTTTTCTGTAAAACAAAACAAAACTCAGAAATG NO: TTACAGAATCAGAGTATTAAAAAATGTACAAGTGTATATGCTTCCCAGACACACATGGATAC 2480 ATTTTTCCTCCACATTTTCACCATGGCAGTATTAAGTAGTGAGTGTGAATGACACAGCATGA AACTGGTTACTGAATCAGCTATGAGCTCAGATGGCCTCAAC FOXN3 ADXCRAD_BP254636_s_at CATCTTGTGGCTCCCCAGTGGTCAGCGGAGACCCCAAGGAGGATCACAACTACAGCAGTGCC SEQ ID AAGTCCTCCAACGCCCGGAGCACCTCGCCCACCAGCGACTCCATCTCCTCCTCCTCCTCCTC NO: AGCCGACGACCACTATGAGTTTGCCACCAAGGGGAGCCAGGAGGGCAGCGAGGGCAGCGAGG 2438 GGAGCTTTCGGAGCCACGAGAGCCCCAGCGACACGGAAGAGGACGACA FOXN3 ADXCRAD_CR735795_s_at TGGACGTTGGACTGTTCATGCGCATCGGGTGTCAGTGACTCATGGAGAAGAAATGGGGTAAA SEQ ID TTTTTAGTGATGTTGCTAATCATTGAATTCTGTTCTCTATTAAATTAAGAAAATGTTCCAAA NO: AGCCATAAGCCTGAAGATTGGCCCTGTGCACGCACGCACACACACACACACACACACACACA 1073 CACACACACACACGAAGGAGAGAGAGAGAAAACTGATGGGGAAAACAAGCTGTGTCTTCTTA ACTGCCCAAGTGAAAAGCAACCAAGTCCAGGAAATTACAATAGCTGTT FOXN3 ADXCRAG_AF138861_s_at GGTTCATTTTAGTTTCAGATAGATGGCTTCACCAAAGAACTCTTGAAAGAATACTGATTAGG SEQ ID GAGGGGCAGGGAAGTAGGAGCTTATGGTATATTATAAGGCTGGGAAAAATCTATGATGCAAA NO: CCCTTTCCACATAGTACT 865 FOXN3 ADXCRAG_U68723_at TTTTTCTGTCTATCAAAACTATTTGATCCAAGTGAAAAAAAAAAAAAAACTAGAAAGCTACGG SEQ ID AACCTGCAATGCGGCCG NO: 1072 FOXN3 ADXCRPD.10462.C1_s_at GTTCTGTTATGTTCATGTAAACCTAAAGAAACAGTGTGGAGGCAGGCGCGATCAGCCGAACT SEQ ID CTAGGGACTTGGTGTTGCTTGGAAGGCATCCATACCTGCATTTTGCATTCTTCGTATGTAAT NO: CATATTGCCAAAGACAAACTATTTCATCATTTATTGTAAATAACACTTTTCCCCAGACCTAC 1418 CATAAAGTTTCTGTGATGTATTGTCTTCCAGTTGCAAT FOXN3 ADXCRPD.12156.C1_at CCGAGCTGACGAGTCATAGATGCATAATTGCAAGATATAACCAGTAGGAGAGAGAGAATACAC SEQ ID AAGGAGTATAACCACCATCGGCGGTGCTCTCTCAAAAGGA NO: 1511 FOXN3 ADXCRPD.12156.C1_s_at AAGGTGCAGCACCATAGACACATCGGTTTCGGCTGTTAAAAGATGGATCGTTTTAAAAACTG SEQ ID TGTTTTCCTTCCTTAATTTTTGGTCAGTGAAGCTAGCACTTGTTTGCTGAACTGTGGAAGAA NO: CTGCAAGGTCACACACATTATTCATGATAAAGCAACCGAGCTGACGAGTC 1512 FOXN3 ADXCRPD.8652.C1_at TAATCGGATGTCAGGCAGAGAAAACGTCGAGGTCACTCGTCTTCCTGAAGGGCCTTGGAGAA SEQ ID ACCGCTGCCCCCGTAACACTGACTCAGTCCACTGGAGACACTAATTCCTGAGCTTTCTGGCT NO: TCTTACTGGGAGGCATGACTGGACCCATTTACGTGAAGGCTCCTGGCCGGAGCGGGGCACGG 1405 GGGTGCGGGGGCGCCGCTGCCCTTCAGCAGGAGCCGACAAACTTTCGCGGGCG FOXN3 ADXCRPD.8765.C1_at TCTTGAAGAAGGTACTGCCCGGCCAGATGGGTGGACCTGATGTGCTTTGATATGCCTGAGGA SEQ ID CAGGTGGGAGGTGTATTGAACACGTGTGGGTGTGGGTGATAAGGTGTCTTTTTCAAAGCCTG NO: AATTAGATTTTGTCTATACTCTGGGTCTATGCACCACAACGACCCTTTCCCAATACTCTGAC 1423 TCCTCTCTTTGTCCACTTTCTTAAAACACTTATTCAATGATAAATTGTGTCTCACTGAGTTT TTCCACCCAGTAGGTGCATTTGCAAAAT FOXN3 ADXCRPDRC.12156.C1_at GTGAACGATCATTTCTGACTTAACCGTGAGATGCTCACGAGTACCCTTCCTGTTGTTTTGTT SEQ ID AGCATTGAAATCGAGACTATTTATTTGGAATATATACAACAGTGTTTTTCCACTGTATTTCA NO: TTTGCAAAAGTTGAGAACTGCTTTCTCTACCCTTTGCCAAATTAATGAATATCCAATATGGG 1953 ATTTTCAAAGACTCCGATATGGTGAACCTATTAAACCTAGAAATTGTATTCATCCTTTCATG ACTGTGGCCTGAGTTCCCCAG FOXN3 ADXCRPDRC.8652.C1_s_at GAGCCTTCACGTAAATGGGTCCAGTCATGCCTCCCAGTAAGAAGCCAGAAAGCTCAGGAATT SEQ ID AGTGTCTCCAGTGGACTGAGTCAGTGTTACGGGGGCAGCGGTTTCTCCAAGGCCCTTCAGGA NO: AGACGAGTGACCTCGACGTTTTCTCTGCCTGACATCCGATTATAAGAAGGGGGCCATGGAAG 1924 ATGAAGAGCTGACCAACCTGAACTGGCTGCACGAGAGCAAGAACTTGCTGAAGAGCTTTG FOXN3 ADXCRPDRC.8765.C1_s_at AAAGGGTCGTTGTGGTGCATAGACCCAGAGTATAGACAAAATCTAATTCAGGCTTTGAAAAA SEQ ID GACACCTTATCACCCACACCCACACGTGTTCAATACACCTCCCACCTGTCCTCAGGCATATC NO: AAAGCACATCAGGTCCACCCATCTGG 1928 FTSJ1 ADXCRAG_BC023584_s_at GGGTAACCATGAACTTGATGGAAGAAAATGTTACATCTTTATTTTCAGCAATGAAACTGAAA SEQ ID TTTAGCCTTACTCCCAAGTTATAAATGCTGGCAACAAATCACAGTAGTAAAAGCAGTACCTG NO: GGATTTTCCCACCAATACAAACCAGTTACAGCAACTGTAATGTAACATAAAAAGGGCATCTT 949 GAAGTATTGTTCATATTTGTCACCTCTTGGAATGATAGCAGATCCTGTAAGTTGATGTATTA ATTAAAAAGCCCATATATTACTGCATCTCAA FTSJ1 ADXCRPD.6080.C1_at ATCCACACAGAAGTGCGGACACCGTTTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNTCCGAG SEQ ID TGGCCCACGCCCTTTGGTGGGGCCCCCTGGAGAATGGGGCAAACACCCCCGGATATATGTAC NO: CGCGTGTCCCCCCTCACCCCCACCTACGGTGTGGGCCAATTTGGCACCCCATTCTCCAAAAA 1704 CGGGCTCCAACGCGCACCGCAAAAAACCCGCCAATCTGTGATGATAGAACTTTCGGTCTCTA AAAGAATCCCACCAATTATACCGAGGGACCTTG FYN ADXCRAD_CB268908_s_at AAGAGTGCCATACCCAGGCATGAACAACCGGGAGGTGCTGGAGCAGGTGGAGCGAGGCTACA SEQ ID GGATGCCCTGCCCGCAGGACTGCCCCATCTCTCTGCATGAGCTCATGATCCACTGCTGGAAA NO: AAGGACCCTGAA 2574 FYN ADXCRPD.4372.C1_s_at CCCAAATCCGAACCTCCTCTGTGAAGCATTCGAGACAGAACCTTGTTATTTCTCAGACTTTG SEQ ID GAAAATGCATTGTATCGATGTTATGTAAAAGGCCAAACCTCTGTTCAGTGTAAATAGTTACT NO: CCAGTGCCAACAATCCTAGTGCTTTCCTTTTTTAAAAATGCAAATCCTATGTGATTTTAACT 1630 CTGTCTTCACCTGATTCAACTNNNNNNNNNNNNGTATTATTTTCCAAAAGTGGCCTCTTTGT CTA FYN ADXCRPD.8770.C1_at GCGCGTCGTTGCAGTTGCGCCATCTGTCAGGAGCGGAGCCGGCGAGGAGGGGGCTGCCGCGG SEQ ID GCGAGCAGCAGGGGTCGCCGCGAGCCGAAGGCCTTCGAGACCCGCCCGCCGGCCGGCGGCGA NO: GAGTAGAGGCGAGGTTGTTGTGCGAGCGGCGCGTCCTCTC 1426 GRB10 ADXCRAD_BG258819_at AAGATCAGCGGAAACGTTGAAAATAACTGGAATGATCATCTGGGGTGGGCCGCTACGAACAG SEQ ID AACCGCAAACAGGATGGCATGAATCTTGCCCTGGATATCTGACATTACACGGACTGTCACTA NO: ACGATGACACC 2496 GRB10 ADXCRAD_BI833263_at GGGCGCGGCGCCAAAAAGCAGACCCCGAAGAGAGAGCCGCATAGGCACAAGAGGCCACAGCC SEQ ID AGATACCAACGGACAACAAGCTGGGCAAACAAATGGCGACACGACCGACGGAAAAAACCACG NO: AGGAGACACAGCCAACCCAGACGACAAACCCGAGACACGCCGCCCACAAGACAGGGAACCAC 2507 AAGCACCCCGACCGGGAGGCACACTCAAAGGACGCCGCACCCACCCACACAGGCAGGAGAGC GCCGACCGCGGCAACAAGAGCACCCAGA GRB10 ADXCRAG_NM_001001549_s_at AAGCTGGCGGTAGATTTGTGATGTCACAGTGCAAACTGCAGTGACTGTAAATTGGCCTGGCG SEQ ID TGTATAAACGTTTTCAGGGAATGCAGAAGGTATTAATGAAGAGACAAAACCTTTATTCCATG NO: TGCTTTGCTTCATTCTGTACATAGCTCTTTGGCTCGTGAACCTAATTGTAAACTTTCAGGTA 1007 TTTTTGTACAAATAAGGGACTGATGTTCTGTTTCTTGTAATT GRB10 ADXCRPD.15300.C1_at CAGAGGTGTGAAGGCTCGCCATAGAGGAGGGCTTGTTGAGTGTCACTCCTGGAGCCTACGGA SEQ ID GTCGCAGGGAGGCCTGGCATGGTCAGGTAGACTTGGTAAGGCCTGACTGCTGGGGAATGTAT NO: CCTGCCAATAGATTCCTGGGCCTGGAACAGCTCTTCTTTGGACACATGCCATCCATCTTTGG 1740 AATAAGACAATCTGGCATTTATGTACCTGGTGGGTTACC IFRD1 ADXCRAD_BI823993_s_at TGTCGAGATAAGAGAGCAGATGTTGGAGAATTCTTCTAGATTTTCAGAACTTGAAGACTATT SEQ ID TTCTAATTTCTATTTTTTTTTCTATTTCAATGTATTTAAACTCTAGACACAGTTTTTATCCT NO: GGATTAACTTAGATAACTTTTGTAGCAGTGGTTATATTGCTT 2616 IFRD1 ADXCRPD.4641.C1_s_at CCTGTCACTGGCATCAACAAAAGGAATTATACCATGAGACCTTATAGCTGTACTTAAAAGCC SEQ ID ATTCAGTTCAGCTATTGGGAGTTCATGATGAATTAGCATATGCCAGAAAGGTTGCTAACCTT NO: AACATCTGAGAGCAGTAACAC 1690 IFRD1 RDCR181_H11_at CTGTCCGTGTTTATTGCAGTTCTCTGGTTTGTCTGGAGTGTTTGCAAGTCAGTCATCATAGT SEQ ID GGCAGCTTCCGCCTGCTACAGGATATTTATATATGGAAGCATACCATGGCAGGAGTGCTGGA NO: AAGGTGGTGTCAGCTAACAGTTGCTTCAGCCAGATAAGGACGGTAACTTCAGTCCAATAAAA 1352 AACCTCATCAGTTACCAACTAAATCAAGGCAT IFRD1 RDCR181_H11_x_at TGTCCGTGTTTATTGCAGTTCTCTGGTTTGTCTGGAGTGTTTGCAAGTCAGTCATCATAGTG SEQ ID GCAGCTTCCGCCTGCTACAGGATATTTATATATGGAAGCATACCATGGCAGGAGTGCTGGAA NO: AGGTGGTGTCAGCTAACAGTTGCTTCAGCCAGATAAGGACGGTAACTTCAGTCCAATAAAAA 1353 ACCTCATCAGTTACCAACTAAATCAAGGCAT IL6ST ADXCRAD_AU280467_s_at GATAACAGTTACTCCAGTATATGCTGATGGACCAGGAAGCCCTGAATCCATAAAGGCATACC SEQ ID TTAAACAAGCTCCACCTTCCAAAGGACCTACTGTTCGGACAAAAAAAGTAGGGAAAAACGAA NO: GCTGTCTTAGAGTGGGACCAACTTCCTGTTGATGTTCAGAATGGATTTATCAGAAATTATAC 2508 TATATTTTATAGAACCATCATTGGAAATGAAACTGCTGTGAATGTGGATTCTTCCCACACAG AATATACATTGTCCTCTTTGACTAGTG IL6ST ADXCRAD_AV662263_s_at CTGATGTAAGTGTTGTGGAAATAGAAGCAAATGACAAAAAGCCTTTTCCAGAAGATCTGAAA SEQ ID TCATTGGACCTGTTCAAAAAGGAAAAAATTAATACTGAAGGACACAGCAGTGGTATTGGGGG NO: GTCTTCATGCATGTCATCTTCTAGGCCAAGCATTTCTAGCAGTG 2434 IL6ST ADXCRAD_BQ887381_at AGGGATTTTTACCACATGAAAGTCATTCCAGTGGACCCTAACCTCCTTATTGGTGGAAGG SEQ ID TTAGTG NO: 2658 IL6ST ADXCRAD_BQ887381_s_at TTTTACTATGGATCAGTCGGCACTCGGGAACAGCAGCAAGGAAAAAAAGCAAATTTCATTC SEQ ID ACATGTTC NO: 2659 IL6ST ADXCRAD_BQ887381_x_at TTTTACTATGGATCAGTCGGCACTCGGGAACAGCAGCAAGGAAAAAAAGCAAATTTCATTCA SEQ ID CATGTTCTGGGTTCATACCTCTTCTCTACCTAATTGGTCATTTTAAATTTCCAGCCTTATTC NO: CCTGGATAAGGGATTTTTACCACATGAAAGTCATTCCAGTGGACCCTAACCTCCTTATTGGT 2660 GGAAGGTTAGTG IL6ST ADXCRAD_CN265168_s_at AACAGTTGGCATGGAGGCTGCGACTGATGAAGGCATGCCTAAAAGTTACTTACCACAGACTG SEQ ID TACGGCAAGGCGGCTACATGCCTCAGTGAAGGACTAGTAGTTCCTGCTACAACTTCAGCAGT NO: ACCTATAAAGTAAAGCTAAAATGATTTTATCTGTGAATTCAGATTTTAAAAAGTCTTCACTC 1054 TCTGAAGATGATCATTTGCCCTTAAGGACAAAAATGAACTGAAGTTTCACATGAGCTATTTC CATTCCAGAATATCTGGGATTCTACTTTAAGCACTA IL6ST ADXCRPD.11859.C1_at AAATGCTTGGCCTAGAAGATGACATGCATGAAGACCCCCCAATACCACTGCTGTGTCCTTCA SEQ ID GTATTAATTTTTTCCTTTTTGAACAGGTCCAATGATTTCAGATCTTCTGGAAAAGGCTTATT NO: GTCATTTGCTTCTATTTCCACAACACTTACATCAGTGAAATTGCCATCTGAATACATTTGAT 1581 CTTCCGAATTAAAATTGTGCCTTGGAGGAGTGTGAGGTGACCACTGGGCAATATGACTCTTT GAAGGATCTGGAACATTAGGCCAGATGTGTAAACAATTAGGTCTCGCTTAT IL6ST ADXCRPD.13648.C1_at GATAGACCATCTAAAGCACCAAGTTTCTGGTATAAAATAGATCCATCCCATACTCAAGGCTA SEQ ID CAGAACTGTACAACTCGTGTGGGAGACATTGCCTCCTTT NO: 1687 IL6ST ADXCRPD.13648.C1_x_at ATATGTGTATAGGATTCGCTGTATGAAGGAAGATGGTAAGGGATACTGGAGTGACTGGAGTG SEQ ID AAGAAGCAAGTGGGATCACCTATGAAGATAGACCATCTAAAGCACCAAGTTTCTGGTATAAA NO: ATAGATCCATCCCATACTCAAGGCTACAGAACTGTACAACTCGTGTGGGAGACATTGCCTCC 1688 TTTTGAAGCCAAT IL6ST ADXCRPD.14481.C1_s_at TGTTTACTAACATATATTGACCAAGTACATCAAGCAGGAGAGATCTTCCTTCATTCTGTTAT SEQ ID AGTCCACATCATTCTAATTTTGCTCAGTTGTTATTAAGAGCATATTCCTAAACCATACACTT NO: TTGTTTCAATAAAGTTTTATTTTGTTGAGATGAATAAAATAACAAAGTTATAAGCTGCATAA 1707 GACAAAAGTTCAATT IL6ST ADXCRPDRC.11859.C1_s_at ACACTTCGAGCACTGTCCAGTATTCTACCGTGGTACACAGTGGCTACAGACACCAAGTTCCG SEQ ID TCAGTCCAAGTCTTCTCAAGATCCGAGTCTACCCAGCCCTTGTTAGATTCAGAGGAGTGGCC NO: AGAAGATCTACAATTAGTAGATCATGTAGATGGCGGTGATGGTATTTTTCCCAGGCAACAGT 1971 ACTTCAAACAGTACTGCAGTCAGCATGAATCCAGTCCAGATATTTCACATTTTGAAAGGTCA AAGCAAGTTTCATCAGTCAATGAGG JUN ADXCRAD_AJ712294_s_at AGGAAGCGCATGAGGAACCGCATCGCTGCCTCCAAGTGCCGAAAAAGGAAGCTGGAGAGAAT SEQ ID CGCCCGGCTGGAGGAAAAAGTGAAAACCTTGAAAGCTCAGAACTCGGAGCTGGCGTCCACGG NO: CCAACATGCTCAGGGAACAGGTGGCACAGCTTAAACAGAAAGTCATGAACCACGTTAACAGT 2719 GGGTGCCAACTCATGCTAACGCAGCAGTTGCAAACATTTTGA JUN ADXCRAD_NM_002228_s_at CAGCCCACTGAGAAGTCAAACATTTCAAAGTTTGGATTGTATCAAGTGGCATGTGCTGTGAC SEQ ID CATTTATAATGTTAGTAGAAATTTTACAATAGGTGCTTATTCTCAAAGCAGGAATTGGTGGC NO: AGATTTTACAAAAGATGTATCCTTCCAATTTGGAATCTTCTCTTTGACAATTCCTAGATAAA 2694 AAGATGGCCTTTGCTTATGAATATTTATAACAGCATTCTTGTCACAATAAATGT JUN ADXCRIH.716.C2_at GATGAAAAGCTGATTACTGTTCAATAAACAGCTTCCTGCCTTT SEQ ID NO: 1287 JUN ADXCRIH.716.C2_s_at CAAACTGCAATAGAGACTGTAGATTGCTTCTGTAGTACTCCTTAAGAACACAAAGCGGGGGG SEQ ID AGGGTTGGGGAGGGGCGGCAGGAGGGAGGTTTGTGAGAGCGAGGCTGAGCCTACAGATGAAC NO: TCTTTCTGGCCTGCCTTCGTTAACTGTGTATGT 1288 JUN ADXCRPDRC.3805.C1_s_at AACTTGTGCGCGCAGCCCAAACTAACCTCACGTGAAGTGACGGACTGTTCTATGACTGCAAA SEQ ID GATGGAAACGACCTTCTATGACGATGCCCTCAACGCCTCGTTCCTCCCGTCCGAGAGCGGAC NO: CTTATGGCTACAGTAACCCCAAGATCCTGAAA 2045 KIF2C ADXCRAD_CV804054_at GCAGCCTGAAAAGCAGGCTAGCAGACAAATAAACAGCAAGAAAACGGCCCCATTGACGACTG SEQ ID GCAATAAAAAT NO: 2651 KIF2C ADXCRAD_CV804054_s_at CTGGAGACCTTTGTGAACAAAGCGGAATCTGCTCTGGCCCAGCAAGCCAAGCATTTCTCAGC SEQ ID CCTGCGAGATGTCATCAAGGC NO: 2652 KIF2C ADXCRPD.737.C1_s_at AGCATCCTGCCTGCGTGGACTGGCTGCTAATGGAGAGCTCCCTGGGGTTGTCCTGGCTCTGG SEQ ID GGAGAGAGACGGAGCCTTTAGTACAGCTATCTGCTGGCTCTAAACCTTCTACGCCTTTGGGC NO: CGAGCACTGAATGTCTTGTACTTTAA 1607 LEPRE1 ADXCRAD_CN309928_s_at AGACGGATGGGTGACTAGACCCATGGAGAGGAACTCTTCTGCACTCTGAGCTGGCCAGCCCC SEQ ID TCGGGGCTGCAGAGCAGTGAGCCTACATCTGCCACTCAGCCGAGGGGACCCTGCTCACAGCC NO: TTCTACATGGTGCTACTGCTCTTGGAGTGGACATGACCAGACACCGCACCCCCTGGATCTGG 1914 CTGAGGGCTCAGGACACAGGCCCAGCCACCCCCAGGGGCCTCCACAGGCCGCTGCATAACAG CGATACAGTACTTAAGTGTCTGTGTAGACAACCAAAGAATAA LEPROT ADXCRPD.1565.C1_at TTGCCTGCCAACACAAGGCCGCAGTCCCCATTTGATCACAGCCACACGAGCAAGAATAACAG SEQ ID GAAATCCAAAGGCAGAAACAACAATTCCAGTAGTGAAGAAATATGCCAGTTCCCGACAGGCA NO: CTACTGGTTGCATCTGAGTCATAGGTGACTCTTTTGGCAATGAAATGGGGGATGGGGGAGAT 1442 GGCGTGGAAAATCAGGACGAATAAGGGCCAGTAAACGCCATAATCCTCTAAGGCACATCCCA GCATAAGAAAAGTCAGTCCAATAGCCCCACTGAAGGATAATGGCCCGA LEPROT ADXCRPDRC.1565.C1_s_at CTGAAGCCCCACTCTGGACCCAGGACATTTTGATGAGATCCAAAGGAGTTGTATGCACATGA SEQ ID AAGTTTGAGAAGCATCATCATAGAGAAGTAAACATCACACCCAACTTCCTTATCTTTCCAGT NO: GGCTAAACCACTTAACCTCTCTGGGTGTTACCTGCTCATTTGTTT 1933 LGALS1 ADXCRIH.2899.C1_at GAAAGACAGCCTCCCGCTGCTCGGTCCCCCAGGCCCCGCCGTCCTTGCTGTTGCACACGATG SEQ ID GTGTTGGCGTCGCCGTGGGCGTTGAAGCGAGGGTTGAAGTGCAGGCACAGGTTGTTGCTGTC NO: TTTGCCCAGGTTCAGCACGAAGCTCTTAGCGTCAGGAGCCACCTCGCCTCGCACTCGAAGGC 1181 ACTCTCCAGGTTTGAGATTCAGGTTGCTGGCGACCAGACCACAAGCCATGATT LGALS1 ADXCRIHRC.2899.C1_at AACACCATCGTGTGCAACAGCAAGGACGGCGGGGCCTGGGGGACCGAGCAGCGGGAGGCTGT SEQ ID CTTTCCCTTCCAGCCTGGAAGTGTTGCAGAGGTGTGCATCACCTTCGACCAGGCCAACCTGA NO: CCGTCAAGCTGCCAGATGGATACGAATTCAAGTTCCCCAACCGCCTCAACCTGGAGGCCATC AACTACATGGCAGCTGACGGTGACTTCAAGATCAAATGTGTGGCCTTTGACTGAAATCAGCC AGCCCATGGC LHFPL2 ADXCRAG_AY309920_s_at CTGGGATTTCTTCTGAGACTGTGGTGAAACTCCTTCCAAGGCTGAGGGGGTCAGTAGGTGCT SEQ ID CTGGAGGGACTCGGCACCACTTGATATTCAACAGCCACTTGAGCCAAATATAAAATTGTATT NO: TACAGCTGATGGACTCAATTTGAGCCTTCAAACTTGTAGTTATCCTATTATATTGTAAACTA 905 ATACATTGTCTAGCATTGATTTGGTTCCTGTGCATATGTATTTTCACTATGTGCTCCCCTCC CCAGATCTTAATTAAACCAG LHFPL2 ADXCRPD.5554.C1_at AGAAGAAATCCCAGTCGTGCCTTTAACTCTTTTGGCCCTTGGGAGTCATTGCAACCCCAATA SEQ ID CAAATGCCGGCCCAGGGATTTCCAGTGGCCACAAGTTATTGCACAGAGAGGTCTGTTCTAAG NO: CCAGACTCTTACAGCTAAGGAGGTGTGAGATTAGCCCTTAAATACTGGTCTAGCATTAGCAT 1723 GGTCTATAAAAGCATGTTAAGAAATAGCTCCTCAGTGATTATGTACCAGCTACTAGTTATCC TACTAAGAGAAAAGGCAACATGGCAGCTTCACATTTC LHFPL2 ADXCRPDRC.5554.C1_at AAATATCTTGCGTTAGCGTGAAAGTATGTTGANTTAACACGGGGAGCCCGCCCCGAACTACC SEQ ID ATGCAAGAACCCCCGCCGAAAAACGAGACTTTTGTGTATCGCCGTGATGTCGGGGCGGTGGG NO: GAACACTCGCCGGCGGGTGGCANAGCGCGGGGGTGGCACAAAGATTGATTACCCCGCAATAA 2008 GACCGGCCCGATCGTGCAACACGGCGCGTCTTCATTCTCGCGCCACAACCCCTATATTATTG TTCTCATCAGCGACGGTTCTTTGTACGACAATGCACACGG LHFPL2 ADXCRSS.Hs#S1449485_at TACTTCCATGCATCAGATTTATGACAAAAGCAATTATATAAGCAGCAAAGGCAAAACCCCCA SEQ ID CGTGTCTGTCTCTGCTTTTCCTTTTATTGCTTTTTTTCATGTGGGCCTCTTTCACCCTCAAT NO: CATTGCTCACTTCCAAGAAGGCTGAGCCTGCATACACCAGGCCCTTCACCACCACTGCCAGC 2070 GCCATTCCCACGACCACACACCCTTCACCCCAGCCCTGCAGAGGCAGGGTTCAGCCCCAGGG CAATCTATCTGGTCAGACTGGTGG LIMA1 ADXCRAD_BP321052_s_at GACCATCCTCCTGCTGAAGTGACAAGCCACGCTGCTTCTGGAGCCAAAGCTGACCAAGAAGA SEQ ID ACAAATCCACCCCAGATCTAGACTCAGGTCACCTCCTGAAGCCCTCGTTCAGGGTCGATATC NO: CCCACATCAAGGACGGTGAGGATCTT 2752 LIMA1 ADXCRAD_BX365807_s_at TTTTATCACAGTATTCTCAGGGTGAAATTAAACCAACTATAGGCCTTTTTCTTGGGATGATT SEQ ID TTCTAGTCTTAAGGTTTGGGGACATTATAAACTTGAGTACATTTGTTGTACACAGTTGATAT NO: TCCAAATTGTATGGATGGGAGGGAGAGGTGTCTTAAGCTGTAGGCTTTTCTTTGTACTGCAT 1229 TTATAGAGATTTAGCTTTAATATTTTTTAGAGATGTAAAACATTCTGCTTTCTTAGTCTTAC CTAGTCTGAAACATT LIMA1 ADXCRAD_CD653165_at AACACAAAAACCTTCTAATCTAGAGATACTTACTAATCTCATTACATGAGAATGCTATGCTG SEQ ID TAGTGTACTGGGATATCACTGAATACCAATCATGATCCAAGATATAGA NO: 2337 LIMA1 ADXCRSS.Hs#S1914330_at CCTCGCTAACACTTGTCAAACTATATTTTAACTATACCCCACAATAAGAAATATTTTACATT SEQ ID CCTACTCAGTTTATACACATACAAATAACTGAAACAAAAACTTTAGAAAAAACCTACCTATA NO: CTATGTCTGATGCACTTTGACATTTTCGATTGCATTCTGTTCTTTTTCATCAAAACAAACAT 2087 GTTGCTTCTGATCGCTCAAGTTGCTTTTACA LIMA1 ADXCRSS.Hs#S3738155_at TTCTCTATGTTGCCTCACTTTATTTCTGAGAAAATAGTTGTTACATATCATTTCTTCCAAGT SEQ ID AACTCAAAGTGCAAATATAAATGTGACAAATCGGGGAAACATTCCAAATTAACTCATTTTAA NO: TCATAGAGTCTTACAGAAGGAAGTAACCAAGATGTCACTTTCTCCAGCTTTCCTTTCTGAGC 2105 AATCCTTCCTAAAATACTCTTGAAAGATGTTTTGGCATCTGTGTGACATTTCTAGCTATTAG ATAGCTCTAGCTAGACAGCTTCTCC LIMA1 ADXCRSS.Hs#S3738155_x_at TAGCCCCTGGAGAGCATGTCTTTTTCTCTATGTTGCCTCACTTTATTTCTGAGAAAATAGTT SEQ ID GTTACATATCATTTCTTCCAAGTAACTCAAAGTGCAAATATAAATGTGACAAATCGGGGAAA NO: CATTCCAAATTAACTCATTTTAATCATAGAGTCTTACAGAAGGAAGTAACCAAGATGTCACT 2106 TTCTCCAGCTTTCCTTTCTGAGCAATCCTTCCTAAAATACTCTTGAAAGATGTTTTGGCATC TGTGTGACATTTCTAGCTATTAGATAGCTCTAGCTAGACAGCTTCTCC LOX ADXCRAD_CV574618_s_at TAGAAGGCAAAGCAAAACTCCCAATGGATAAATCAGTGCCTGGTGTTCTGAAGTGGGAAAAA SEQ ID ATAGACTAACTTCAGTAGGATTTATGTATTTTGAAAAAGAGAACAGAAAACAACAAAAGAAT NO: TTTTGTTTGGACTGTTTTCAATAACAAAGCACATAACTGGATTTTGAACGCTTAAGTCATCA 1013 TTACTTGGGAAATTTTTAATGTTTATTATTTACATCACTTTGTGAATTAACACAGTGTTTCA ATTCTGTAATTACATATTTGACTCTT LOXL2 ADXCRAD_BI825165_at GGAATAACAAGAAAGATCTATGAACAGAACACAAACAAACACAGCAAGCTAACAAAA SEQ ID NO: 2695 LOXL2 ADXCRAD_CF619371_at CCATGGTGGGTCTGCCCGCCAGCTGGGCCTTGGGAATTCGCCCACCAAACGCCTTTCAAGAA SEQ ID AACCTTGGTTATTGGGCCCCGGAAGATGTTCAACAGCCCAACAA NO: 2405 LOXL2 ADXCRAG_AF117949_s_at GAAACTTGTCAGAAGGCATAGGAGTTGTGCGAGGGCTGGATGGGAAGTCTAGATTTAAACAG SEQ ID CCACCAGGCAGCTTATCAAAGCAAGAGGGCATCCGTTCACAGGACAGGGGCTCCCAGCAATT NO: CCCAGTGGCAGTGGGGGGTGGCTGGCCCAAGCCCCAAGTCACCCAGACACAGGGGACTTCCC 858 CTTGTGTCAACAGCATGCTAGGGCCCAGCAAACTAGAGGGTAGGTAGGACCACCTTGGCACC AA LOXL2 ADXCRAG_NM_002318_s_at CACCCCTTGTTTTTCAAGATACTATTATTATATTTTCACAGACTTTTGAAGCACAAATTTAT SEQ ID TGGCATTTAATATTGGACATCTGGGCCCTTGGAAGTACAAATCTAAGGAAAAACCAACCCAC NO: TGTGTAAGTGACTCATCTTCCTGTTGTTCCAATTCTGTGGGTTTTTGATTCAACGGTGCTAT 1014 AACCAGGGTCCTGG LOXL2 ADXCRPD.4590.C1_at GGGTTGCTCTGGCTTGTACGCTTTCCGGAATCTCGAGGGTCCGTCAGGGCTGAAGACCTGCC SEQ ID CAGGCACACAACTCACCACGGCCGGTAGCCCATTCTCGCAGGTGACATTCTTCATGGGGTCC NO: AGTGACACCTGGGGGCCCAGCTTGCAGCTGGAGATGTGGGCCTCTGTGCCGGTGCAGTCCAT 1674 GGAGAATGGCCAGTAGCGCTGCTTCCTCCGTGAAGCACACATTTTGTACACTTT LOXL2 ADXCRPDRC.4590.C1_s_at ACCGTCTGCGACGACAAGTGGGACCTGGTGTCGGCCAGTGTGGTCTGCAGAGAGCTGGGCTT SEQ ID TGGGAGTGCCAAAGAGGCAGTCACTGGCTCCCGACTGGGGCAAGGGATCGGACCCATCCACC NO: TCAACGAGATCCAGTGCACAGGCAATGAGAAGTCCATTATAGACTGCAAGTTCAATGCCGAG 1997 TCTCAGGGCTGCAACCACGAGGAGGATGCTGGTGTGAGATGCAACACCCCTGCCAT LPP ADXCRAD_AI079544_at GACCTAAAACTGTCTCCAGGACACAAGGCTATTCCAAGCAACATTAAGAGAGAGCTCTGTAG SEQ ID GAAAAGAGGGTCTTGTCAACACAATTCTCAGAATAA NO: 2852 LPP ADXCRAD_AI079544_s_at GGACTCACAAGTCATACCCTACTAAACACCCATCAGATGGACTTGTCTACTTTATTGAGAAA SEQ ID CAACAGAAGATAGACCTGCAAGTCCAGCTGTTCATCTACCTCCACCCCACAGCCCAAGCCAC NO: ATTCCCACCCTTTGTGGATGAAGCTCAGGGATGCAGATCCCATTCCAAGATCC 2853 LPP ADXCRAD_AL833171_at TTGGCCTATTCTGGACTGCAAATAGCATTGCCAAGCACTTCCCTTAAATAACTTCTCTTTTT SEQ ID TGCAGGACTATCCTCTCAGCCCTGCCAAAACCCCATCACCTACTCTTTCTTTACTACTTTGC NO: CTATTTAATGCTGGAATTTTTATTTAAACTGTAGCTGATTTACTGAAGGTAATTAAGTGCTT 2784 TCATGCTGTAGATCTCCTGCTAGACTACAGGCTGTACTTGGGAGTGAGAGTGAACCAAATGT AA LPP ADXCRAD_BM456598_at TTGTCTTGGAAGTATCTCATAGGTCTTTAAATGAGTAAAACATTTTTATGCCAGAAGGTGAT SEQ ID ATAATGGATGTTAGTGTTTTTTATTGGATTTTACAGGAGTTTTAGTCAGATAATGAGGACAG NO: AGACCTCCACTTGAATTCTTTACCACCATTTCAGCAATATTTTTTTAATGGCCTTTCACTTG 2400 GATTTTGGCTTAAATAAGGGCCCCGAACAAGATCCAAAACTTTGTGTCCTCAGGGAAGGGCC ATTAATA LPP ADXCRAD_BM456598_x_at TTGTCTTGGAAGTATCTCATAGGTCTTTAAATGAGTAAAACATTTTTATGCCAGAAGGTGAT SEQ ID ATAATGGATGTTAGTGTTTTTTATTGGATTTTACAGGAGTTTTAGTCAGATAATGAGGACAG NO: AGACCTCCACTTGAATTCTTTACCACCATTTCAGCAATATTTTTTTAATGGCCTTTCACTTG 2401 GATTTTGGCTTAAATAAGGGCCCCGAACAAGATCCAAAACTTTGTGTCCTCAGGGAAGGGCC ATTAATA LPP ADXCRAD_CX867590_at TCTTGATGGGCCTTTTGTCCCAGGACTTCCACATTT SEQ ID NO: 2618 LPP ADXCRAG_BX648297_s_at GTAGGGTATGACTTGTGAGTCCACAAGGCCAGCAGTATATATGCTGAATGGACTGCTTAGCA SEQ ID GTAACACACTGGAAAAATCCAAAAAGAATGGATTTCAAGTTGGCAAAAAATGCATTAGAAGT NO: CAGCAGTGTGATGTGGTCAGGAGAACAACCAGAGTGACTGTGGGATGAGGTCTTGGATAGCT 984 TTGTT LPP ADXCRAG_NM_005578_at AAATAAGTCATGTGTCCCAGCATAAGGCATCAGGTTGTTAGATGCTGGCATCTCTGCAGCTC SEQ ID AAAGATGTGGGTTCTTTTTCTTGTCATTAACACATTGTTATTTCTGTAGGACCAACTTCTCT NO: GATCAAAATTACTTTTCTGGGTATGTGCTGATTAAGGGGGTGGACTTATCAACACTATAATT 1031 GTTCCCTATGAAAGATTCCACAGAGATGTTTATGGTGA LPP ADXCRPD.11183.C1_at GAATGACCAACAATTTGGCTTTCCTAGAAAGAGAAGAGAATATCTGAATTCCCTGTAAACTG SEQ ID GTAAATCCTCTACCATCAGTCCTGAATTCTGAGGGGGCCTGATATTTAAGCAACAAAACTTA NO: GAAGGTTCCACCTGTTATTCCTAGCTCTGTCACTAAAAATCGTGTCCAAACAGAGGTAATAC 1437 GAATGTGTTACCCGTTCCCGAAATTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCC AGAGCACAGAATGGATCCAGTGTAGTAGTGCAGGTGACCA LPP ADXCRPD.14604.C1_at AATACCGAACTAATGGTCCTTGTCTCAATGACCTGCCTATCCTTTGTCCCTTCATGGGAATC SEQ ID TTCTCACAGATCAAGTTACTATGATCTACAAGGCCAGTTCCCATAGCCTCGTTCCACTTACA NO: CACGATCTTAACCATTTCTGTCCAGTGGGAGTCACCCACTCACCTCCTAAAACCTCTATGCA 1731 TGCCCCATACCCCTAGTCATAATACTCTTATACAAATGTTTAACACTTTGCAGTTGAAGACC CAAT LPP ADXCRPD.16626.C1_s_at CTAGATGATTCCAGTGCCCTTCCATCTATCTCTGGAAACTTTCCTCCTCCACCACCTCTTGA SEQ ID TGAAGAGGCTTTCAAAGTACAGGGGAATCCCGGAGGCAAGACACTTGAGGAGAGGCGCTCCA NO: GCCTGGACGCTGAGATTGACTCCTTGA 1828 LPP ADXCRPD.16635.C1_at TTAGTTAAGAACATGACCCGAAGAGTGAAAGGTATTTCCTGTTCCAAATAGGAGCCCAGTCT SEQ ID GCATTTTCTACTACATGATTTAGTAGAAAGACACATTGCATTTGAACCATATTTCTTCTGCT NO: AGCCAATTCCATCTTATCTACAACTTTTTGATAATTATTTTGAGAAATAGATCTAGATCACA 1831 GCCTTCCAATTCCTAGGCCAGGATACTT LPP ADXCRPD.5328.C1_s_at GAGCTATAGTACATGTGTGTTATGAATGAAATATGACAGCATGTTCCATACCCCTGCTTTAG SEQ ID CCATCTGTGGGAAACCAGCAAACTGAAAAAGACACCTCTGCAAAATGTGCCTCAAGTCCATT NO: TCTTGGGATCGCTCGTTTGGTGCACTCTCGTGGGAGACAATCAGAGAACAACATATACTTGT 1693 GCCTTATTTTCA LPP ADXCRPD.9098.C1_at GCATCCACAGTGAATGGGATCCCATCCAGGCTGCGGTGGCACATCACCGCAGGGTGAAACAG SEQ ID GTGAGGATGATTAGGCCTTCCCGGTGGCTCGGAGAATCCGCTCCATGATGGGCTTGGAACAC NO: ACATTGCACTGCTCCAGAGTATTAATGTAGCAGGGCTCGCAGTATGCTTTCTTTTCCACAGC 1872 ATAAAATGGCTGCCCTCGGAGCTTGTTGTTGAGATGATGCANGTNAAACAATCCACGTGGAA GACCTGATCCATGGCAGTGCATTCTGTACCTTTCCCAACTA LPP ADXCRPDRC.9098.C1_s_at AGGAGACTGTCCGTATTGTGGCTTTGGATCGAGATTTCCATGTTCACTGCTACCGATGCGAG SEQ ID GATTGCGGTGGTCTCCTGTCTGAAGGAGATAACCAAGGCTGCTACCCCTTGGATGGGCACAT NO: CCTCTGCAAGACCTGCAACTCTGCCCGCATCAGGGTGTTGACCGCCAAGGCGAGCACTGACC 2040 TTTAGATTCAGTCACCTGTTCAGCCG LPP ADXCRSS.Hs#S1294625_at TGAAGGTCTTCAGCAAAAATTTGGACTGTAAACACAGCTTGGCATTATCAGCATTCTGTTAA SEQ ID GTTCAAAGAAGAGATAGTTACAACAAATACAGCTTGCTTTATTTCTGAAACAAAACTGTGCA NO: CATATTTGTGGCCATACTACTAATTAACCTGTAGATTGTTCCTTTCATCTATTCAGCGTGTT 2063 TTTCTGCCCCCTGTTACAACAGTGTTGGGTTACTTTTCCCATATGGACTATATTTAAACAGT TCCCTTATAGGCATTAGAG LPP ADXCRSS.Hs#S1908923_at TGCCCTTTTTTGTGCCTGGGCTTCATCCTTGGAATGTTTTACCTCATGGGCCATGAGACGGC TGCCTGCTGAAACCCAAACTATAGATATCCCTGTTCCCATTTAGGGGAAAGAGCCTGGTTTG SEQ ID CTATATTCTCATAGGCTTGGCTGACTGTATATTTCTGAACCAGTCATTGAAGCCAAGAGAAT NO: GGGATTATGGTAATATGAACCACTATTCTCCTGAAACTGAATTTGGACATAGTCCCATCCAA 2119 ACCTCATGGTACTTACACAGTGG LPP ADXCRSS.Hs#S1910599_at GAAGACAACAACAGGTAAACGAGAAAATCCTTGGAAAAGAACACCGTTAATTTACAATAGTA SEQ ID TATGTCTCTCTCTGGCCAACGTACTTTGTTTCATGACACTACTGGCATCATCCATCCCAAAT NO: ACTTTCGGTCGCTGTGTGTTTCAGACTCTGAAAAACCTTCAAATAACACAATAAAACCTGCT 2123 CCTCTTTTCCTTTAATCTTACATAAAGGCAGTTCTCTTAAGTCTATAGTCAAAGC LPP ADXCRSS.Hs#S1921588_at GATTCAGTGGGCAACTGTGGCAATAGTTCTTGGCTAACCTGGTCACTATGGAAGTTCTTTCC SEQ ID GTGGAAAAAGATTCTCCATCCTTCAATTTGAGATAAGATTTACTAATTGAGACCTCATTTGT NO: ATCTGATTTTAATCTTTGCATCATTTTAGTTTTAATAAACTAACTTTCCAACTTACCAGATT 2104 TTCGGGTTGACAAAGACCATTATTTAGAGAAACACAGGCAAAGGAAAGTCTAAAAGCTTTGG CTGGAATTTCAACTGCTTCTGGTCCAGAAT LPP ADXCRSS.Hs#S2732094_at CAAAAATTCCTGCATATACCCACTCAGGAAATATTTTCCCAAATCTTCTCCATCTCAACTCT SEQ ID GTGAGGCATTGGAAGAGGTGCTTTTAGGCATAGACTGATGCACTCTATATATGATGTCTCGC NO: CCTCCAGGGCAGCACACAGTTTAGTGAGGTAAATGTCTCATGAATATTCCACAAGATCCACC 2109 TTGATAATGCTCTAACGTTACTCATAGAGGGCTGAATGTGGAAAGATGCTTTCGTCTGGTGG CAAA LPP ADXCRSS.Hs#S2984275_at GTAGCAGAAGCAGGACTGGAACCCAGAACCCAAGTTGGACCACTAGACTGGTGCCTCTCCCT SEQ ID AAGCCCACTCTGCCTCTTCCATGTCTGTGAATGAGCTTACCACTCCTAGCTATGCAAAACTG NO: CATAGAACCATTTCAGCAAGAGGCTCAGGTAGCATTAAAGAAGTTCCCACCTCAACGATGTC 2160 AATTTTTTGTTACTGTTGTCTTGAGGAAGCATGTTTGCTTTTAAACGCTCCCAAATTAAAAG CCATTCTCAGCCTTCCTACAATTGTATG LPP ADXCRSS.Hs#S3748577_at ATGGCAGTGAGCATTTATTCCGGGCTGAGTTTTACACTACCCATACTGTCTCTAACTCTCCC SEQ ID AACACTCCCACAAGGCAGGTGCTATTATCCCCATTTTACTTTTGAGAAAATTAAGGCCTAAA NO: GAAGTGAGAAAGCTTGTCCAAACCGCTATAGCTCTTGGGCAAAGGCATTAGTGACCAATGTG 2197 TATTTGACTCCAAAGCCCAGGATGTTAGCCACAGTGCAGGGCTACTATCCTTTTATACAATC TGTCAGGCTTCTTCCATCCGTGGCATGTATTCATCTA MAP4K4 ADXCRAD_BG110060_at GAAAGCGCGAAAACAACACAGAGAACACAACAAGAGGAGATGAGTGGGCGCGTCAGAATGAA SEQ ID AGCGGGGGCCACCACCACGCAACCACCATGAAAGAAGACGACGCAACAGAAAACAAAAAAAG NO: GAGGCCGACACCATAACGGAGGAGAACAGAAGAGAGGAGAAGACATCGATCGGGGAGAAAAG 2682 AGACCACAGCAACAGACGGAACAAGGATGACGCACAACGGAGCAGAAGAA MAP4K4 ADXCRAD_BP228866_s_at ATATCGAAGTCCTGGCTTTTCTCGTTTTCTCACTTGCTCTCTTGTTCTCTGTTTTTTTAAAC SEQ ID CAATTTTACTTTATGAATATATTCATGACATTTGTAA NO: 2343 MAP4K4 ADXCRAD_BQ647365_at GTAGAAGCAGTGTGATCCAGGGATTACTGGCCTCCAGAGTCTTCAAGATCCTGAGAACTTGG SEQ ID AATTCCTTGTAACTGGAGCTCGGAGCTGCACCGAGGGCAACCAGGACAGCTGTGTGTGCAGA NO: CCTCATGTGTTGGGTTCTCTCCCCTCCTTCCTGTTCCTCTTATATACCAGTTTATCCCCATT 2704 CTTTTTTTTTTTCTTACTCCAAAATAAATCAAGGCTGCAATGCAGCTGGTGCTGTTCAGATT CT MAP4K4 ADXCRAG_BC065036_s_at TAGGTTTTCGTCTTAGTTGTAGCACACTTACCCTAATTTTGCCAATTATTAATTTGCTAAAT SEQ ID AGTAATACAAATGACAAACTGCATTAAATTTACTAATTATAAAAGCTGCAAAGCAGACTGGT NO: GGCAAGTACACAGCCCTTTTT 975 MAP4K4 ADXCRPD.1395.C1_at TTTCTTCTGCAAGTGCAGACTGTGGTAAAACTTTTGTTGCACGTCTAGGTTTAAACAAAAAT SEQ ID TAAACCTTTAACTGAGGCAGTGCTAATACTGTCACACGACAAAGTTCTGGCCATTATACAAA NO: ATGCACACGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNA 1397 GAACCATCTGCACATGATTTAGGCAACCTGGTACACAGAAAAATGACTGAGTTCTTGGCCAG MAP4K4 ADXCRPD.17623.C1_s_at AAGTTCCATTGTGAACGTGCCTGGTGAGTCTACTCTTCGCCGAGATTTCCTGAGACTGCAGC SEQ ID AGGAGAACAAGGAACGTTCCGAGGCTCTTCGGAGACAACAGTTACTACAGGAGCAACAGCTC NO: CGGGAGCAGGAAGAATATAAAAGGCAACTGCTGGCAGAGAGACAGAAGCGGATTGAGCAGCA 1402 GAAAGAACAGAGGCGACGGCTAGAAGA MAP4K4 ADXCRPD.2985.C1_at AGTAGGCGGCTTTGGCCTTCAGCACTGCTCCAAACTCATACAAATGAAACATCCATTTCCAT SEQ ID CTTCTTTTACTTCCCCAAAAAGTAAGCTTCTCAGCTTGTCTTTACAGGTATACACAAAACCA NO: CCAGCTGCTGTGTCTGCATTCATGAGTGGATGTACTTGTCTTACCAGATGTTTGTAGCTCAA 1603 AGGAGGGCCTTTTTCAAAAAGATGGAACCAGGAACAGGAAACTGACAAGAGGTCAGAGTGGG TGCCAAGTGGGATGGGAAGCAAACAGGTACAAATGGCCGGACGCGT MAP4K4 ADXCRPDRC.1395.C1_s_at AATGCAATGCACTAAAACTATTTTAAGAATGTAGTTAATTCTGCTTATTCATAAAGTGGGCA SEQ ID TCT NO: 1923 MAP4K4 ADXCRPDRC.2985.C1_s_at ATTTGTATGAGTTTGGAGCAGTGCTGAAGGCCAAAGCCGCCTACTGGTTTGTAGTTAACCTA SEQ ID GAGAAGGTTGAAAAATTAATCCTACCTTTAAAGGGATTTGAGGTAGGCTGGATTCCATCGCC NO: ACAGGACTTTAGTTAGAATTAAATTCCTGCTTGTAATTTATATCCATGTTTAGGCTTTTCAT 1973 AAGATGAAACATGCCACAGTGAACACACTCGTGTA MAP4K4 ADXCRSS.Hs#S1921392_at GACAAAAGCCTCTGAAGTAGGCATTATTCCATTTTACAGATGAGGAAACTGAGCTTTATCAT SEQ ID GCTTAAAAGTATGTATTGCTGTCTTGGGGAAAAAGGCAGGATATGACTACTAAATAATGAGG NO: TTAACTGCCTAGGAGGCTCATACACTATAAATTCACCTTGAAAATTATTTATGGGCCTCAAA 2101 TTTATGTTCCTGGGAAAGAGGAGCAAAAGATTAAATCATTTTTATTAGTTCAGTGACAATTC TAAAAATGAAACCCAGAAATGTACTCACTCCTAACCACTC MAP4K4 ADXCRSS.Hs#S1921392_x_at GACAAAAGCCTCTGAAGTAGGCATTATTCCATTTTACAGATGAGGAAACTGAGCTTTATCAT SEQ ID GCTTAAAAGTATGTATTGCTGTCTTGGGGAAAAAGGCAGGATATGACTACTAAATAATGAGG NO: TTAACTGCCTAGGAGGCTCATACACTATAAATTCACCTTGAAAATTATTTATGGGCCTCAAA 2102 TTTATGTTCCTGGGAAAGAGGAGCAAAAGATTAAATCATTTTTATTAGTTCAGTGACAATTC TAAAAATGAAACCCAGAAATGTACTCACTCCTAACCACTC MAP4K4 ADXCRSS.Hs#S2732925_at TACCATGATCTCTTTGTGCTTCCTCATCTTTCATTGGCAAATCTCTGGAATGGGCCATATAA SEQ ID ATGCAGCCCTCAAATCCTTAACAGCTTATGATTCGGCTTCCATCACTCACATTTAAGCTTTT NO: CTTAAAGATCACTTTCCACCATCATCAAGAAACAACTGTAGTCAGTTCTCTTGTCCTTCCAT 2135 TTCTTAGGACTATCAAAATATTGTGATTTGATATTTGACTCACCCTACTTCTCTAACCTTGT ACCGTCACAGT MAP4K4 ADXCRSS.Hs#S2984613_at TTGTTATGGAGCAGGTTCAGTAATAAGAGTTGGTGAGTATTATTCAGAAGAGAAGCTGCCTC SEQ ID TTGGGTTGAGTAATTAATAAAGTGATTCATTGGGAGGTAGTTTTTTGTCTGTAAGAATCTCT NO: AAGGAATGATCACAATGATAAGTTTTAGGACATCCCGTTTTAAAAACTGGACTCTTACAAAC 2157 TTTGTTATCTAGATAGCATTAGGTATAACTAAATTGGGGAGACAAAAGTGAAAAACGATTAA CCATATAAGGGTGGTTTCA MAP4K4 ADXCRSS.Hs#S2984613_x_at TTGTTATGGAGCAGGTTCAGTAATAAGAGTTGGTGAGTATTATTCAGAAGAGAAGCTGCCTC SEQ ID TTGGGTTGAGTAATTAATAAAGTGATTCATTGGGAGGTAGTTTTTTGTCTGTAAGAATCTCT NO: AAGGAATGATCACAATGATAAGTTTTAGGACATCCCGTTTTAAAAACTGGACTCTTACAAAC 2158 TTTGTTATCTAGATAGCATTAGGTATAACTAAATTGGGGAGACAAAAGTGAAAAACGATTAA CCATATAAGGGTGGTTTCACAATGGCACGTG MAP7D1 ADXCRAD_BU178034_x_at GTAAATAGCTTGTGCTCAGACTCCTCTGCGTGGAGAAGGTGGGTGCANGAGGCAGACCCTCC SEQ ID CCCCAAAGCCCCCTGGGGAGATCTTCCTCTCTCTATTTAACTGTAACTGAGGGGGGATCCCC NO: AGGTCTGGGGGATGGGGGACAACCTTGGGGCCACAGGATACTGGGTTTGCTTCAGGGGGTAC 2681 CCATGGCCCCCCTGCCCTCGGCCTGGGAATCAGTGGNTACTGGCATCTGAATTAAAATGTTC TTCCCCGA MAP7D1 ADXCRPD.6828.C1_s_at TTGCCTTGATTTGGTGGGGTACAGTGGATGTGAATACTGTAAATAGCTTGTGCTCAGACTCC SEQ ID TCTGCGTGGAGAGGGTGGGTGCAGGAGGCAGACCCTCCCCCCAAAGCCCCCTGGGGAGATCT NO: TCCTCTCTCTATTTAACTGTAACTGAGGG 871 MAP7D1 ADXCRSS.Hs#S1907164_at GGCTTAATGTGATTTGCTCCATAACACTGTGCCAATGACATTTCATCAGGGTTGGCAAAATT SEQ ID GTGAAGAAAATATTTGTATTCAGGGTCAATAGTGTGCCGGGTCACAAGAGGAGTTCCAAACT NO: TCTTGTTTGCCTCTTGAGAAGTTTTTCTTGTTGAGCTGCTGGAGTAAACACTCATTATTATT 2126 TTTATTAACTTCTACCTGTGTGGCTTAGTCCAGGAAGCTGCCCAAACACTATTGAGATGGAG TTGTTTTGCTTCTCTTCAAATGTTTATCTTTT MARCKS ADXCRAD_AV732105_at GAATGTACTTTGCTTTACAAAATGCTATAACTCTGCTTAGGNGTCTATTTTCTTGAGCCACT SEQ ID AAAGCGAAAATAATGT NO: 2375 MARCKS ADXCRAD_AV732105_s_at ATTTTAAACTCAACCAAGCTGTGATAAGTGGAATGGTTACTGTTTATACTGTGGTATGTTTT SEQ ID TGATTACAGCAGATAATGCTTTCTTTTCCAGTCGTCTTTGAGAATAAAGGAAAAAAAATCTT NO: CAGATGCAATGGTTNTGTGTAGCATCTTGGCTATCATGTTTTGGAAATACTGGAGAAGCTTT 2376 GACCAATT MARCKS ADXCRAD_BM557039_at AAAATAGCTTTTGAGGATTAACGCAAAAATAAAATAACTCCTTGTACCAGGTCCAGAAATTG SEQ ID GCCTATTAAAACCTGAATTTGGGCAGTATTTTATAATGGGCCATTTGGCTTGTGGGTTACA NO: AAA 2623 MARCKS ADXCRAD_CD103045_at TGAGGGAGGTTTACAGCACTACAGGTCTTGAGTTAAGAAGGAAAGAGGAAAAAGAAAAAACC SEQ ID CCCATACCCCGATTTAAAAAAAAAAAAAACCGATCCTTAGTCTTTAGAAGTTCCATTTAAAC NO: CCATAGGGAACCTTTTCCCCTTAATCCTCATGGTTAAGCCTGTACCCAGTTCCAG 2612 MARCKS ADXCRAD_CD110028_at CAACGGCAGCGTCCCGGCCCGCCGAACAAAGAGGAAGCCCGCGGGCCGCCGGGAAGCGGGGG SEQ ID GCGGCCTTCACCCCTCCCTCGGGCCCGAAAAAAGGGTGAAGTCGGGTCCCGCCGAACCGCCA NO: TGCCCTCCCTAAAGG 2374 MARCKS ADXCRIH.653.C1_s_at AGTGAATAGTCAAAAATCCTGTTAGCAAACTGTTATATATTGCTAAGTTTGTTCTTTTAACA SEQ ID GCTGGAATTTATTAAGATGCATTATTTTGATTTTATTCACTGCCTAAAACACTTTGGGTGGT NO: ATTGATGGAGTTGGTGGATTTTCCTCCAAGTGATTAAATGA 1112 MARCKS ADXCRIHRC.653.C1_at TTTTTGATCCATTATTCCAATTAAGAATGCGTGTCAAAACCTAATTTGTTATTTTTCTAATG SEQ ID AGTTTAAGATTTGGCATTCAGTTGTTACACATGTGGTTCAATGATTTATCATGAACCCTAAA NO: CTGCACACTGCTCAAAAACAGCAAAACAGATGTGCATTAAATGAAATAATGTTTTTGATACA 1305 TATCTTAAATTTCAATCAGTTTAGGGTCCTTTGAAGGAAAAGATATCCAGTTATCGGGTGGC AAAGAGCAGAGGAGGTAAACTCCTCGTGCCG MARCKS ADXCRPD.2741.C1_at GGGTCTCCTCTCTCGGGCGGCTACTACTCCACACCGAGAGGGAGTGTCTTACAAGGCGGCCG SEQ ID GCGTGCAAACAAAAAAATAATATAACCGNNNNNNNNNNNTCGGTCGCACCTATATTCGAGCA NO: AAGAAAAGCGTGGGTGGTAAAGTATATTCTATAAACACAATTTCCTCGCGCCCACCACGGTG 1908 GAATACCCACTCCCCATAAAACGGCCGGTGGGAGAAGACTCTCGAACACCGCCCG MARCKS ADXCRPD.3926.C1_at AATCCTCCCGTCTCTCCAAAACCATCTCCCCGTCCCCTGACATTGCGGCGCTCTGANNNNNN SEQ ID NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NO: NNNNNNNGAGAGAGCTTTTTGGCGCGCGCCTTTCCCCTGGCGCTTTTCTCCCCGGGAGGATT 1672 GTTCTCCACTTTTCGCCCGTCATAGCCTAAATCCG MARCKS ADXCRPD.4423.C1_at TTCAACAAAGAAACTCAACAGATCCAAGAGGGGAAACAAAGAGCCTCGGGTTGGTGTAACGA SEQ ID CGGGGCGAGCAGCAGCAGCAGCGGCGGCCAACAGCGGCAGCCTACAGCACACCGGAGGAAGG NO: GGGGTGGGGGTGGTGGAGAGGACAGAACAGAACCGATTAAATACACTCCGGATAAAAAAATT 1648 TTAGTCGAAGAGATCAAAAAGCAGCAGCACAGGAGGGAGGGAAAAAGGGTGGAAAAGTCGAG CACCAAAAAAGGAGCCCCAGT MARCKS ADXCRPD.4423.C1_x_at CCCATGCTGGCTTCTTCAACAAAGAAACTCAACAGATCCAAGAGGGGAAACAAAGAGCCTCG SEQ ID GGTTGGTGTAACGACGGGGCGAGCAGCAGCAGCAGCGGCGGCCAACAGCGGCAGCCTACAGC NO: ACACCGGAGGAAGGGGGGTGGGGGTGGTGGAGAGGACAGAACAGAACCGATTAAATACACTC 1649 CGGATAAAAAAATTTTAGTCGAAGAGATCAAAAAGCAGCAGCACAGGAGGGAGGGAAAAAGG GTGGAAAAGTCGAGCACCAAAAAAGGAGCCCCAGT MARCKS ADXCRPD.8271.C1_at CCGTCCTCGGCCTTGGGCGAAGAAGTCGAGGAGGCGGCCGACGCGGCCTCTCCCTCCGCGGC SEQ ID CGTGGGCGAGCCGGGCTCGGCAGCCTCGCCTTCCGCGGGGGCCTCCTTCTCTACCGGGCTGG NO: CCCCGGCCTCGGGGGCAGCGGCGGCTGCCGGCTCACCTTTCGCGGCCGCG 1829 MARCKS ADXCRPD.8271.C1_x_at CCGCTCAGCTTGAAAGACTTCTTGAAGGAAAAGCGCTTCNNNNNNNNNNNCGGGGTCTCGTT SEQ ID GCTGGGCGAGGGCGTGGCCCCGTCCTCGGCCTTGGGCGAAGAAGTCGAGGAGGCGGCCGACG NO: CGGCCTCTCCCTCCGCGGCCGTGGGCGAGCCGGGCTCGGCAGCCTCGCCTTCCGCGGGGGCC 1830 TCCTTCTCTACCGGGCTGGCCCCGGCCTCGGGGGCAGCGGCGGCTGCCGGCTCACCTTTCGC GGCCGCGAAAGGCGACGCCGCCCCGCTCCCGGCGGACGAGGGCTCCTCCTTG MARCKS ADXCRPDRC.4423.C1_s_at CGTTACACCAACCCGAGGCTCTTTGTTTCCCCTCTTGGATCTGTTGAGTTTCTTTGTTGAAG SEQ ID AAGCCAGCATGGGTGCCCAGTTCTCCAAGACCGCAGCGAAGGGAGAAGCCGCCGCGGAGAGG NO: CCTGGGGAGGCGGCTGTGGCCTCGTCGCCTTCCAAAGCGAACGGACAGGAGAATGGCCACGT 1981 GAAGGTAAACGGCGAC MARCKS ADXCRPDRC.8271.C1_s_at GAAGGCGAGGCTGCCGAGCCCGGCTCGCCCACGGCCGCGGAGGGAGAGGCCGCGTCGGCCGC SEQ ID CTCCTCGACTTCTTCGCCCAAGGCCGAGGACGGGGCCACGCCCTCGCCCAGCAACGAGACCC NO: CGNNNNNNNNNNNGAAGCGCTTTTCCTTCAAGAAGTCTTTCAAGCTGAGCGGCTTCTCCTTC 2032 AAGAAGAACAAGAAGGAGGCTGGAGAAGGCGGTGAGGCTGAGGCGCCC MARCKS RDCR156_A02_at GAAGTGAAATAATCATGCCTGCCCTGGCTGCTTCTGTGAGTGGAAGATCATAATTGGAGTGC SEQ ID ATGAAAGACTTTGTAAACTGTTAAGTGCTCTATAAACGTTAGCATTTTACTCAATAAATTTT NO: TATCACACATTCGATGGAATAAGGAAAGAGAATTGAAATAATACAGTTTTTCTTCATTGCCT 1347 TAGATTATAATTCAGATATAATACAGTTCATTACATTTCATAGTTGTGGCTATTTCAGTAAA T MARCKS RDCR156_A02_x_at AGTGAAATAATCATGCCTGCCCTGGCTGCTTCTGTGAGTGGAAGATCATAATTGGAGTGCAT SEQ ID GAAAGACTTTGTAAACTGTTAAGTGCTCTATAAACGTTAGCATTTTACTCAATAAATTTTTA NO: TCACACATTCGATGGAATAAGGAAAGAGAATTGAAATAATACAGTTTTTCTTCATTGCCTTA 1348 GATTATAATTCAGATATAATACAGTTCATTACATTTCATAGTTGTGGCTATTTCAGTAAAT MSN ADXCRAG_BC011827_s_at AGAATGACAGACTAACTCCCAAGATAGGCTTCCCCTGGAGTGAAATCAGGAACATCTCTTTC SEQ ID AATGATAAGAAATTTGTCATCAAGCCCATTGACAAAAAAGCCCCGGACTTCGTCTTCTATGC NO: TCCCCGGCTGCGGATTAACAAGCGGATCTTGGCCTTGTGCATGGGGAACCATGAACTATACA 933 TGCGCCGTCGCAAGCCTGATACCATTGAGGTGCAGCAGATGAAGGCACAGGCCCGGGAGGAG AAGCACCAGAAGCAGATGGAGCGTGCTA MSN ADXCRAG_M69066_s_at CTGACCTTGAGGAGTCTTGTGTGCATTGCTGTGAATTAGCTCACTTGGTGATATGTCCTATA SEQ ID TTGGCTAAATTGAAACCTGGAATTGTGGGGCAATCTATTAATAGCTGCCTTAAAGTCAGTAA NO: CTTACCCTTAGGGAGGCTGGGGGAAAAGGTTAGATTTTGTATTCAGGGGTTTTTTGTGTACT 998 TTTTGGGTTTTTAAAAAATTGTTTTTGGAGGGGTTTATGCTCAATCCATGT MSN ADXCRPD.2854.C1_x_at GTACTTTTCCACTTTGGATTTTGCAAATGCCCCCTAACCCTTTACTGGTTGTCCCTATGGGG SEQ ID AATCCAAGTGG NO: 1582 MXRA7 ADXCRAD_BX099460_at TGATCACCCCACTGGCAGGACAATTCACAGTTCTTGAGCAAACTGAGTTAGGGAGGGTATGC SEQ ID TAACGACAGAACCTATGCAAGTTCTTAGAAATATTTTTTGTTTGCTGAAATAAAGCTCAATC NO: AACACACTACCTTAAAAAAAAGTGGGAGCAGTGGCATTTCCATGCCTCATGCTCACCATCAT 2442 GAGGTTAACTTCCCGCCGTCGCCTCTTGCCTGCCAGGGGTTTTTCGGGAGCCCCTCTCTGTT CCACTCTGATTCCTTTTGNTTCTTTGCTGACCATTCACTCTCTG MXRA7 ADXCRIH.2503.C1_at ATGGCAACAGCCACACAGTCATTGCCTTCAACACAGAGCCACGTGTCCCCAAACAGCAATAG SEQ ID TCATGCCCTTGTCCAGGCTGGGATCTAATTGATACAATAGGTCGTTGACTCCCTCCTAGTAG NO: AGCTATCTAGGTTTGTCTGGAAAGTTTCCGACCCTGGCTTATAGGCACCACACCTCATGTAC 1205 TCCTCATGGCTTGGATCTCTGTATTCAGCCTTTGTTCAGTCC MXRA7 ADXCRPD.17734.C1_at AAAGGCCTCTAACCTGCTGGAAGATAGGGACCAAGTTGAGTATTTTATTTCTTCTGTCTACA SEQ ID GCATCCAGCATAGTTCTAATTAAATACAATTAGGCAAGTACTCAAATAAGTCTTGCCTAATT NO: ATATTTAAAGTAAGTATCCTGCTTAAGTGAGAGAAATTCTTGGCAGATCTTACCTCTAGTAC 1422 TATTGTTTAGTGCCAGGATGGAAGGTGAGTCTCTGAATTAGACTTTTTGCTGAAAGAACGCT CCCAGCTGGGCATGCT NR2F2 ADXCRAD_CB217549_s_at ATTATAATTGTTGATATTTTCCCTTTTTAAAAAATACCATTGAAATCAGCATGACAAAAATA SEQ ID ACACTGTTGGCACTTATAGGTAACGTGATTGATTCAGTATCTTAGAGTTTACAGTTTGTGTT NO: TTAAAAAAACTGAAGGTTTTTTTTTAAGTGCAACATTTCTGTATACTGTAAAAGTTATAATA 979 ACTGAACTGTTTGGTCGAGTCTTTGTGTGTTA NR2F2 ADXCRAD_CB956496_at GCGAGCGAGATCTTTGGAGAGATTTTTTTTTTTGCCTCCTACTTCTGTCTTGAAGCCAGACA SEQ ID ATCGACTTCAGCTCTCCCTCCCCTCCCTCTTTCTCCACGTTCTGCTCCCACTCGCTCTCCTG NO: TCCCCTTCCCCTCCCCTCCCGGCGGAAAGCCCCCCGAAACCAACAAAGCTGAGCCGAGAGAA 2487 ACAAACAAAACAAACACACCGGGCCAGACAAGCCATCGACAAAACTTTGCAAAGTCAACC NR2F2 ADXCRAD_CB956496_x_at GCGAGCGAGATCTTTGGAGAGATTTTTTTTTTTGCCTCCTACTTCTGTCTTGAAGCCAGACA SEQ ID ATCGACTTCAGCTCTCCCTCCCCTCCCTCTTTCTCCACGTTCTGCTCCCACTCGCTCTCCTG NO: TCCCCTTCCCCTCCCCTCCCGGCGGAAAGCCCCCCGAAACCAACAAAGCTGAGCCGAGAGAA 2488 ACAAACAAAACAAACACACCGGGCCAGACAAGCCATCGACAAAACTTTGCAAAGTC NR2F2 ADXCRPD.4673.C1_at GAATTGCCATATACGGCCAGTTAAAACTGCTGCCGGACAGTAACATATCCCGGATGAGGGTT SEQ ID TCGATGGGGGTTTTACCTACCAAACGGACGAAAAACAATTGCTCTATGACTGAGGAGGAGAC NO: GGTGCGGAGGGAAGGGAGGCGAAGCAAAAGCTTTCCGAATCTCGTCGGCTGGTTGGGGTACT 1691 GGCTCCTAACGTATTCTTCCAAAGCACACTGAGACTTTTCCTGCAAGCTTTCCACATGGGCT ACATCAGAGAGACCACAGGCATCTGGAAGA NR2F2 ADXCRPDRC.4673.C1_s_at ATCCGGGATATGTTACTGTCCGGCAGCAGTTTTAACTGGCCGTATATGGCAATTCAATAA SEQ ID NO: 2001 NR3C1 ADXCRAD_AI934556_at GATGAATGTGCGCTTTGGAAATGTTTAAATAGATATGAAATGATTAAATAAAATCACAGTCT SEQ ID TGTGCAACATCCATAGCTTACAGTTATTTGGCAACTATGAAACCACAGTTACTAATGGAATT NO: AAGACTTTNTAAAAAATTGCAAATGTACTTATTTGTATATGAAAGAGGTATTCAGCTATTAA 2815 CTCAGTATTTAATAAACATTGATATGTAATTTTTACTTGAAATGGCCTAAGGTTTATAATAC CAACTAGTTCATAGAGCTTTTTT NR3C1 ADXCRAD_BQ433598_at GGTTACTTTCACATACAGCCCTCCCCCAGCAGTTGAATGACAACAGAAGCTTCAGAAGTTTG SEQ ID GCAATAGTTTGCATAGAGGTACCAGCAATATGTAAATAGTGCAGAATCTCATAGGTTGCCAA NO: TAATACACTAATTCCTTTCTATCCTACAACAAGAGTTTATTTCCAAATAAAATGAGGACATG 2380 TTTTTGTTTTCTTTGAATGGGCTTTTGAATGTTATTTGTTATTTTCAGAATTTTGGAGAAAT TATTTAATAAAAAAACAATCATTTGGCTTTTTGAATGCTC NR3C1 ADXCRAD_CA392568_at GTGCCTTTTATAGCTATTACTGTCTGGTTTTAACAATTTCCTTTATATTTAGTGAACTACGC SEQ ID TTGCTCATTTTTTCTTACATAATTTTTTATTCAAGTTATTGTACAGCTGTTTAAGATGGGCA NO: GCTAGTTCGTAGCTTTCCCAAATAAACTCTAAACATTAATCAATCATCTGTGTGAAAATGGG 2379 TTGGTGCTTCTAACCTGATGGCACTTAGCTATCAGAAGACCACAAAAATTGACTCAAATCTC CAGTATTCTTG NR3C1 ADXCRAG_X03348_s_at AAAGTGTCTTTTTACCTACGCAGTGAAATGTCAGACTGTAAAACCTTGTGTGGAAATGTTTA SEQ ID ACTTTTATTTTTTCATTTAAATTTGCTGTTCTGGTATTACCAAACCACACATTTGTACCGAA NO: TTGGCAGTAAATGTTAGCCATTTACAGCAATGCCAAATATGGAG 1078 NR3C1 ADXCRSS.Hs#S1907985_at GGGACTAATGTAGCCTTGCTTCTGAGATGTGGCCCCTAGGTCTCTACTGAATGCCCGGCATA SEQ ID TTTAATTAGATCTTTCTTTCCTCTATGGCCTCAAGGGATTTCACCCTAAGTATGCACAAATT NO: TTTATTCAGCCGAAGACTGTACAGATTTCTGGAGGCCTTTCTTTGTGTACCTCCTTCGTTTC 2121 CAGTAGTCTGACCCATAAATTGTACAGATTTCTG NR3C1 ADXCRSS.Hs#S821188_at AATGAGCAAGCGTAGTTCACTAAATATAAAGGAGTTTGTTAAAACCAGACAGTAATAGCTAT SEQ ID AAAAGGCACAACTTCCCTTTTCTGATATACACTTGTAAACTTTTTTTCAGGTTTCCATGCAT NO: AAATCAAAAATGCTATCCTAACTATACAGGGGGGGGATACACCAACAGAAAGTCTAGAAAAT 2224 TTCATCCAGCCAACTGTGTAAAAAAGTATGAAGAGAAAGTTCCTCACACAGACTTTGGGCAC TGGTGGTTTAGGTGGCATCCATCTTTGACTGT NT5E ADXCRAD_BC015940_at TTCTTTACACAGGTAATTGTTTCAAAAGGATTGCATGGGCCAGGATGTCCAGATAAGCACTG SEQ ID TGTCTCTTTTGCCTTTGTAACTGTTATTACTCTTTTTACTGCTATTTAATATGTAATGTATA NO: TTATATGATCTATAATATATATGTAATATACATTAAATGGGAACATGTGCAAATCTTACAAA 2778 A NT5E ADXCRAD_BG611920_at TAAAAATTGGACAGATTAGCCCAAAAAAAGACACAATCACAACAAACAAAACAAAAACTATT SEQ ID GTTGGCGGCACTGTGCGCCCCAAAGAAACTCTGTAAAACACCTAGCGGTTAGGCACAGCGGC NO: CCCATAGGAAAGCGAACATGTGCAAACATGTCCCCAGAAAAACCCGGAACAAAAAAACGGCG 2714 CGGAAACGCACCCAAAAAACACGCCCGGGGAACCGCGGTTTTGGACAAACCAGAGACATCAC AACAAAA NT5E ADXCRAD_BM704188_at GGAGAAAGCTCCCTCCGTTCTGATGCTTTTGAGCTTATCAGGGACACCCTGCAGCAGAAATT SEQ ID CCAGCTGATCCTTCAGCCTTCAGAGTTGATGAGGTGGGGCTCACACACATCTGGATTTGAAG NO: AAGAATCGTGGGTTTCAAGAACTCTGTGGTCTCTTAAGCATTGGTATTCCACAGCTACACTT 2446 CCCTGATACTTTGCACTCAGTAATGACAA NT5E ADXCRAD_BX404438_s_at TTGTGGGAATCGTTGGATACACTTCCAAAGAAACCCCTTTTCTCTCAAATCCAGGGACAAAT SEQ ID TTAKTGTTTGAAGATGAAATCACTGCATTACAACCTGAAGTAGATAAGTTAAAAACTCTAAA NO: TGTGAACAAAATTATTGCACTGGGACATTCGGGTTTTGAAATGGATAAACTCATCGCTCAGA 2316 AAGTGAGGGGTGTGGACGTCGTGGTGGGAGGACACTCCAACACATTTCTTT NT5E ADXCRAG_NM_002526_at CTTTGAACCACTTTGCAATTGTAGATTCCCAACAATAAAATTGAAGA SEQ ID NO: 1015 NT5E ADXCRAG_NM_002526_s_at GCAGCAAAATAATAGCCTCGGTTCTATGCATATATGGATTGCTATAAAAAATGTCAATAAGA SEQ ID TTGTACAAGGAAAATTAGAGAAAGTCACATTTAGGGTTTATTTTTTACACTTGGCCAGTAAA NO: ATAGGGTAAATCCTATTAGAAATTTTTTAAAGAACTTTTTTTAAGTTTCCTAAATCTGTGTG 1016 TGTATTGTGAAGTGGTATAAGAAATGACTTTGAACCACT NT5E ADXCRPD.5241.C1_at CACAGAGTTCTTGAAACCCACGATTCTTCTTCAAATCCAGATGTGTGTGAGCCCCACCTCAT SEQ ID CAACTCTGAAGGCTGAAGGATCAGCTGGAATTTCTGCTGCAGGGTGTCCCTGATAAGCTCAA NO: AAGCATCAGAACGGAGGGAGCTTTCTCCCCTTCTCTCATCTCATTAAAATGAGCTTTCTTGT 1683 TGTGGGGGGTTGGGGAGGGACCTTTAAAACCAAACAATGGTGCCCTCTTATCATCTTTTNCT GTCCTCCTTTCTCCAAGTTTCCAGAGGG NT5E ADXCRSS.Hs#S1299958_at ATTGAACAGAGAATCTACCCCAAAGCTGTGAGCTTAATTACTCTCAAGCTCCGGGGTCAAAG SEQ ID AGATCTGGTGTCCATTCTTATCACGTCTCCCTTTTTGCGGGGATGGTGCCTGTTAATTTATT NO: CAGCTTCTTCGACGCGGTTTCCCTTTCAATAAGATTGAGATAAAGCATTTTTCGAAAGATCT 2064 AGATTGAGATAAAGCATTCTTTGAAAGATCTAGCAGTAAA NT5E ADXCRSS.Hs#S3735513_at TTCCCTCTGGCAAGGAAAGACTCAGATAAAATTCCCCATGACTTCTAAAGGTGCTCCTGGGC SEQ ID ATTACTTTTCATTGTTTTTCCTGGGGATGCTGTTTCCTCAGAATGTCGTTGTATTATAGTAC NO: ATTCCTTAAGGGATATGGTTTTCATTTTCCTGAATGTTGCTCCTTTCTCTCATTTTACCAGC 2207 AACTTGTTACTCCCTTTCACTTTCAGACTCTTTTCTCTCTTTCCCTTCTCCTTCAGCAACTT CTCTCCCCATTGAAGTTAGAAGT OSBPL3 ADXCRAD_CN419328_s_at GGAAATCCGACGATGACTCTTGGGTGAGCAACGGCACCTATTTGGAACTTAGAAAAGATCTT SEQ ID GGTTTTTCCAAACTGGACCATCCTGTCTTATGGTGAAAAAGTAAAGAAGAAAGATAACATTA NO: GTGTATTTCTCCTGTGCTTGCCTTCTGAAGTGGCACAAACCTGTGTTTATATATTTAAAAGA 2741 TACTCTAGGATGATCACTTGTGCTTAGCTTAACATTGTAACTCTTTAAGTCTATATTTTCCT CAGTGCGTTTCTTTACAATTTCAAATGTTACCCTGA OSBPL3 ADXCRAG_AF392444_s_at TCTGTGTTGGAAACCTGCGTCATGTAAATATCTGCAAATCATGACAGTCTAAAGTGCAAACC SEQ ID ATTTTCAGAGACTTTGGGGAATGCAGTGATCAGAAGTGGCTAATTTATTTTATTTCTGATTA NO: TTTTATCCAGAGGGTACTTTTTTAATGGATATTTGTAAATCTTCCACTTAACCACTGAAAAT 877 TATTTTGTTTTAATCCCACCCTTCCATCCATACCTCTGCCTCCCCAAAAAGCTCCTATTAAT TTGCTTATCCCCCTCATGTAGCTAGTTGAATGTG OSBPL3 ADXCRPD.12932.C1_at GATTCCATTAATACAAAGTCCTAGAACAGGTAAAACCAGATGGTAGTGATAGAAATCAGAGG SEQ ID CATCAGGGTTAGAGTTGACTGCAAAAGGGCATGAGGGAGCTCTTTGGGTGAGGGAATGTTCT NO: TTGAGGTGATGATTGAAGCGATGGTTACATAGGCATATACATGTGCTCCAAACTCATCAGTC 1670 TGTACAT OSBPL3 ADXCRPD.2801.C1_at TGCTTCCTTTTCAAGAAGGTGCCGTATACGTCTTATATAAAAATATACATTCCATTAATCTT SEQ ID ATATCCACTCCCTAACCACTAAAATGCAAATGAAAATATTCTTCAGACTCCAGCACCAGCAG NO: AATTGTTCTGTATGAGCAATTCAAGAGCTGTCTGAGGCAAAAAGATATTTCAGCTACCAAAT 1579 TAAACTTGGGTAGCTTACGCATGGGTGAGTAACCCTGGGAATTCT OSBPL3 ADXCRPD.2979.C1_at ATAGTATTGCTCGTAGCCTTTCGGCATAGGATTTGCTCTCCATACACAGGCAGAAGAGGAGC SEQ ID CGCCGCCACAGTAGATGCTTTCATGCCATTTCCCAAACAGCCGATGAACCGCTTTTCCACTC NO: CTGTCAAACACTGTGCCTTCAATCTCATGGGCATTAGTGCTCCAGTATTTTGCCTTTATAAA 1602 ATTCACTTTCA OSBPL3 ADXCRPDRC.2801.C1_at TTGAGATACTTTAAAGAATTCCAGAGCATATC SEQ ID NO: 1968 OSBPL3 ADXCRPDRC.2801.C1_s_at ATATGTGTAGTAGTTGAATTGTGTTATCAAAGCATGTCCAACTTCTGTCCAGATGACATTAA SEQ ID AACCAAAGCCTAATTGTTAAGCCTCTTATTCTAAAGTCCATAGCAATGCTATGGAATATCAA NO: GTATAATGATGTAGTAAAAAGATTTCTCCAGA 1969 OSBPL3 ADXCRPDRC.2979.C1_s_at GAAAAGCGGTTCATCGGCTGTTTGGGAAATGGCATGAAAGCATCTACTGTGGCGGCGGCTCC SEQ ID TCTTCTGCCTGTGTATGGAGAGCAAATCCTATGCCGAAAGGCTACGAGCAATACTATAGCTT NO: CACACAGTTTGCGCTGGAATTAAATGAAATGGATCCATCATCAAAGTCTTTATTGCCACCTA 1972 CTGACACTCGATTTAGGCCAGACCAG OXSR1 ADXCRAG_BC008726_s_at GTAATATGTGCCAATGCTATTTGTGAAATGTTTGGTCTTTCTAAACGACTAAAGGATTTGTT SEQ ID GGGTTTTTGCTTAAGTTTTGAACCAAATCCTAGAGCCAGCTGATAATATTTAATAATCTAGA NO: GGAGAGAATAATGATGTACCAATAAGTGGAGATTCCTCCTTATGATGTATGCTAGGTTATGG 925 AAGATGTAAAATATTCAACTTTTTCCTCCTTTTTTTGGACTTTGTATTTTACTGCATGTTT OXSR1 ADXCRPD.10116.C1_s_at TGAGATGATCAGACACCGGAGTTCAACGTCCCAGCAGTCTTGGTAAAAGGAGGGAGCCTACT SEQ ID GAGCCAGGAGGGAGAAAAGAAGATTGACCAGCTTGCTAGAAAAATACTTAGCNNNNNNNNNN NO: NNNNNNNNGTGGAGGGGGGACGGAGAGGAACAAGGATGGGGAGGTAGGAATGAGGTATAGAA 1859 AAGAGATAGCATCTTCTTTGGCACAAGACTAGTGGCT PCMT1 ADXCRIH.1058.C2_s_at GTTGTAGATACAATCAGCTGCTTTGTTACCTTAAAACTAGGCATTTGTAAATATTAAACCAT SEQ ID AAGATGGCAGGTGATGTCCTGTAAACACTCAGCTGTTCAGATTGGACATAACTGACTTAGTT NO: CTTCCCTTCTCTCTCTCTCAAAATTATAGGAGACTTGTAGTTTAGTGTGGTTTTCTGTTTCT 1291 AATTTGCTGCTGATAATGTATATGAACTTAACATGCTGTGTAAGCTGTGTCCTAGTTCTTGA ACAGTTTATGCAGTGCTGCTTTGCCAAATAAAGTT PEA15 ADXCRAD_CN347927_at TGAACTGTCCTTCCATTTGGGATATGTTACATTAGAGTGAGAGAGAGAATAAGGAGCCTTTC SEQ ID TTATGGAAGAAATGGGAGAAGAGAGACAGGGTTCTTTTCAGCAGAGTCTAGTAGTTTCTCTG NO: TAAGGCAAAATAATCTAAAAAGACTAACCTGCCCACCCACTCCTTATATTGCTGTGAGATTG 2608 CCCCTATCTTGTGCTCTTCTGTCTGCAGTGTGCACGGCCTTGTTCTAACCC PEA15 ADXCRAD_CX867144_s_at GTGTTTTCCTTTGCACCGATCCCCACCCCAATTCAATCCCGGAAGGGACTTACTTAGGAAAC SEQ ID CCTTCTTTACTAGATATCCTGGCCCCCTGGGCTTGTGAACACCTCCTAGCCACATCACTACA NO: GTACAGTGAGTGACCCCAGCCTCCTGCCTACCCCAAGATGCCCCTCCCCACCCTGACCGTGC 1154 TAACTGTGTGTACATATATATTCTACATATATGTATATTAAAACTGCACTGCCATGTCTGCC CTTT PEA15 ADXCRPD.14289.C1_at AAATCAGCACATTCCTCCTACTTCCCTTTCCTCCACTCCCCCCATATCTTTAAAGTGTGGAA SEQ ID GCAGAAAGGACCTGCATTTTCCTACATTGAGGAGCTGACATAGGGGTAAGGTATGGGAGAGG NO: TAGGTGGATCCAGGGAAAA 1684 PEA15 ADXCRPD.14289.C1_s_at AAAAGCCAGAGTTCCATGTTTGTACTCCTTGTGCTGGACTGTTTCCTGAGTACCAGCAGGTC SEQ ID CCTTTTTGTCTC NO: 1685 PEA15 ADXCRPD.14289.C1_x_at AAATCAGCACATTCCTCCTACTTCCCTTTCCTCCACTCCCCCCATATCTTTAAAGTGTGGAA SEQ ID GCAGAAAGGACCTGCATTTTCCTACATTGAGGAGCTGACATAGGGGTAAGGTATGGGAGAGG NO: TAGGTGGATCCAGGGAAAAGCAGTGGGGACGGAAGGCAAGAGACCACTCAACCCCCACCTGG 1686 AAGGGGCAAAGAAAAGCCAGAGTTCCATGTTTGTACTCCTTGTGCTGGACTGTTTCCTGAGT ACCAGCAGGTCCCTTTTTGT PMP22 ADXCRPD.5015.C1_s_at AAATCATAAAGCCTTCATCACTCCCACATTTTTCTTACGGTCGGAGCATCAGAACAAGCGTC SEQ ID TAGACTCCTTGGGACCGTGAGTTCCTAGAGCTTGGCTGGGTCTAGGCTGTTCTGTGCCTCCA NO: AGGACTGTCTGGCAATGACTTGTATTGGCCACCAACTGTAGATGTATATATGGTGCCCTTCT 1634 GATGCTAAGACTCCAGACCTTTTGT PPAP2B ADXCRAD_CD678016_s_at TAAACTGTGTCTCGACCTGTGTTATTTACATTAGCTGCTTAAAAAAGCATTGAGTTAATTTT SEQ ID TTTAAATATCAACTAAAATATCATAGTTCTGTGGTAGACATTGTTTTATAATGAAATAACTG NO: CAACTAGAGAAAACTGTATAAAAACATTAAATTGTCAGTATTTTTGTAAGGTTCCATTTTGT 1024 AAAGAGAATAATATTCAAAGACTTTTGTAGCATACAAAGTGAAAACTTGTATCTGCGAAACT ATACTTGTATTAAATGTGCTTTT PPAP2B ADXCRAG_AF480883_at GCTCGTAACACAACTCTCATCTCAGGCTCTTCTAAAGAGCTTTTGTATTCTAAAGAGGATTT SEQ ID TTCCATCAGAGAGGTAGGAGCTGTAGGAACCCCGAGGGCAGATAAGCAGCCCTCACTCTAGA NO: TAAGGTATGCTGGGGGAGCTTACTGAGGGAATCCTGTACACAGCCCACATCAAAGGAAGGCT 878 GAGAATGGCCTGTGGCTCC PPAP2B ADXCRPD.13412.C1_s_at ATGTTCTGGCAGGATTTGCTCAAGGAGCCCTGGTGGCCTGCTGCATAGTTTTCTTCGTGTCT SEQ ID GACCTCTTCAAGACTAAGACGACGCTCTCCCTGCCTGCCCCTGCTATCCGGAAGGAAATCCT NO: TTCACCTGTGGACATTATTGACAGGAACAATCACCACAACATGATGTAGGTGCCACCCACCT 1641 CCTGAGCTGTTTTTGTAAAATGACTGCTGACAGCAAGTTCTTGCTGCTCTCCAATCTCATCA GACAGTA PPAP2B ADXCRSS.Hs#S524340_at TGACTGATAGCTGCCGCTTATGGTTACTTAGTAAAAACTCCTGTTGCTAAATGGCTCAAATG SEQ ID GATGTCTGTGTGTTTATTTTGCCATCTAATACAAAGCATAAATTTTTCTTACTCCAGTAGCT NO: CATCAAACCCTTGAATCTTTCATCATAAGCACATTGAGGCAGGAACTATGCCTGTGCCATCC 2129 TCACACCTTTGCAAGTGGCACTCAATAAATGTTTCTCAAGTATTGTTCAGACTCAGTGAGGG TCACATCCCCAGGAGGAA PRNP ADXCRAD_CX762421_at ATAACATTGGTTATCTGGACTATTTTGGACTAGTGCACAGGTGAGCTAAACAATCTAGACAT SEQ ID CTGAATACTTGCTGGATCTCTGCTCTCACACTAAGTCATACTATGCTACTATAAATCAACTA NO: TAAGAATCATTAGAACGAACTCGCAG 2673 PRNP ADXCRAD_CX762421_s_at CTCTTTGTCCCGGATAGGCTAATCAATACCCTTGGCACTGATGGGCACTGGAAAACATAGAG SEQ ID TAGACCTGAGATGCTGGTCAAGCCCCCTTTGATTGAGTTCATCATGAGCCGTTGCTAATGCC NO: AGGCCAGTAAAAGTATAACA 2674 PRNP ADXCRIH.1264.C1_s_at CATAGGACAGACTTAGGAGTTTTGTTTAGAGCAGTTAACATCTGAAGTGTCTAATGCATTAA SEQ ID CTTTTGTAAGGTACTGAATACTTAATATGTGGGAAACCCTTTTGCGTGGTCCTTAGGCTTAC NO: AATGTGCACTGAATCGTTTCATGTAAGAATCCAAAGTGGACACCATTAACAGGTCTTTGAAA 1241 TATGCATGTACTTTATATTTTCTATATTTGTAACTTTGCATGTTCTTGTTTTG PSMD2 ADXCRAD_CF130280_s_at ACAGGGTTCCAGACGCATACAACCCCAGTGTTGTTGGCCCACGGGGAACGGGCAGAATTGGC SEQ ID CACTGAGGAGTTTCTTCCTGTTACCCCCATTCTGGAAGGTTTTGTTATCCTTCGGAAGAACC NO: CCAATTATGATCTCTAAGTGACCACCAGGGGCTCTGAACTGTAGCTGATGTTATCAGCAGGC 1018 CATGCATCCTGCTGCCAAGGGTGGACACGGCTGCAGACTTCTGGGGGAATTGTCGCCTCCTG CTCTTTTGTTACTGAGTGAGA PTPLA ADXCRAD_CD299090_at ATCTCTGCAAAACAAGTGCTTTTTCCAGAATAACCAAGATTTACTGAGTCCAAGTTTTTAAT SEQ ID AACAAGAAATAAACAACCTTTGTGAAAATAATCATGGGATTGGTATGGGTTTT NO: 2585 PTPLA ADXCRAD_CD299090_s_at ATTATTTTCTTCTTATAACCATGGCATCATATATACCTTTGTTTCCACAACTCTATTTTCAT SEQ ID ATGTTACGTCAAAGAAGAAAG NO: 2586 PTPRK ADXCRAD_AU145587_at TGCTGGGCTGTTCTCTACCGAATACCATAAAACTGAATATTGTTCACCACTATGGTCGATCT SEQ ID TTCTAACTTTAAAGAGTACACAACTGAACTCAATTACTCCAAAGATATGTGAAAACACAGAA NO: AAATGACCCCTGTTAAAAGAGTAAACCTAGCTTTTGNTTTACTTTCCTTTTATATAAAAAAA 2864 GATGTACAGGGTTCTCTTCT PTPRK ADXCRAG_Z70660_at TATTGAGCCAGCAGCTGTTGTACCTGTTACACTTGTGCAGAAAGATTTTAATGTGGGGGGTG SEQ ID GGAGACTTTTACATTTGAGAGGTAAAAGTATTTTTTTTATGAAGTTGTGTATCTTAATAAAA NO: AGAACTGAATTAGTTTTTATTACTATATTAAAGCATCAACATTTCATGCCACATAAAATTAT 1097 ATTTAATAAGAACCAGATTGAAATGAGAACGTATTGGTGTTTGTACAGTGAACATGCCACCT TTTTCCATGGTTTCAGGTAGTGCAGCTACCACATGTT PTPRK ADXCRIH.91.C1_at TATAATGTGCTTTCTCCATATAGACATATTTACACTTGAGTCTTTGGCTTATGTTATTTTCT SEQ ID AAAAAGAACTTTAAATGATCCAGCCATCATTGCACATTAAAAGAAAATAAGCCAGTTATATA NO: TATTTATATATTCCCATAGAGATCTGCTACACTGGAAACATATAAAAAACGAACTTTACTAT 1182 GAATTTGCACAGCTTTTCTTTTCTTCTTCCTTTTAAGATTCATCAGCTTTCATTTTAGAAAG GGAGCCTCGTGC PTPRK ADXCRIHRC.91.C1_s_at CAATGCCAGATTCCTGTTTTGCGCATTGTCATGGGATTCTTAAGTGAACCTTTCTAAATGTG SEQ ID GTCTTGTTCACATGCTCCACGTAGCTGTAACTTCACATCATCAGCTTGCAGTTTGTAATTGA NO: CTAAAGCATTCCAGTGTCCTCTTTCTAGATTGCCAGCTCATGACATGGTGCTTATAAAGA 1318 PTPRK ADXCRPD.10919.C1_at CATAATAGTTCCAAGCTAAAAACAACCCAAATGTCTGTCAGCAGTGCAATGTATAAATAAAT SEQ ID GGTGGCATATTCATAAAGTGAAATATTGTACTGCAAATAAATGAAAGAACCATTGCTTTATA NO: CAATAACATGAATGAATTTCGCAAACACAATCTTAAGGGAGAGAAACCAGATGCAAGAGAGT 1525 ATGTATATATACATTTATATAAATTATGTAAGTTTCAGAAACAGGCAAAACTAATCAATGAT ATTAGAAATCAGCATATTATTTACTTGAAGAGGATTTGGGCAACTT PTPRK ADXCRPD.11104.C1_at GGCAGTGGATAATCGTCCGGCCTTCCCCTTCCTCGCATTCCTCCTGCCACTTTTCCACCTGA SEQ ID AGTATCAGTTTCAAGAATGACCTTTTGGAACCAGGCACTTCTCGATGAGAAGCCCATCCTAG NO: GTACTGAAACTGTTGCACCATCAGATAACCTTCCTGTGGTCTTGTTAGATTGCATATCCTAA 1425 AAATCCGGTTGATCACATCACAGTCCATTGAACAAGACATACATTCCACTTGGATGGGGCCA TATCGTAGCATCCCTTCCTCTGGCCAGTACTGAGGGCAGCCCTG PTPRK ADXCRPD.13194.C1_at ATCACATGAATATATCTGCCTGACAAAAATTTGGGAAGTCCAGCATCTCTGATTTAAAAAGA SEQ ID AGAAACTATTTGTAATTTTAGTCTCTTGTTCTTAATGCAGGATCTGACCATTGGTTAGTAAT NO: GCAACAGCTGCGATTAGCAATGAAGGAAAACTATTTTCAGAGTCTTCTCATGACCTAGCCAC 1595 ATTAGCAATCTAAAAATACAAACAGGAAAAGTTTTTAAAAGCTTAACCTTTTATAAAGTGAC TAAACTGCATAAGCCATCAGCCACAGA PTPRK ADXCRPD.13198.C1_at CACCGGAGGTAGTTGATAGATCGAGAATACACAAGGACACTCACAGTCACACATAGAACCTA SEQ ID GAAACAACACTCCCCAAAACAGATGTAGATTCAACAAAATACTATAAAAAGCCATAAAGCAT NO: ATTCAGTATATAATGTTTAAATTGTTCTGACATATATGTTGTTTGTATACCCGCACAAATGT 1596 TACTGTCATTAAACTAATGATCCTATTTTCTTCTTCTCAAAAAAAGTCCTAGAAATCTGTTT GTGATGGCTTGATGAAGTTTAGTCACTTTATAAAAGCCACCTTGG PTPRK ADXCRPD.14082.C1_at ACTAATATGTTCAAAGTGCCAGGATTCAGTCCTTTCTGGCTATATAATAGGTAACTGAAATC SEQ ID AATGCAGTGAGTGTCGTTCTCCTTCATTGTAGGCAGCTGAAGTCTGGCTTTTTCTCCAGGGT NO: CGTGATCTGAAGAGTCCACTATCATATAGGAACCTTGGGGCATCTCGGGTGGTAGATAATGA 1647 GGCTCTTGAGCACTAACATGCACCCATTCAAAGTCATCATACAGATCCTGGTGGTAATCACA GGCCCCTGGAC PTPRK ADXCRPD.6814.C1_s_at TATAGCATATGATCACTCCAGAGTGATTTTGCAACCCGTAGAGGATGATCCTTCCTCAGATT SEQ ID ATATTAATGCCAACTATATTGATGGCTACCAGAGACCAAGTCATTACATTGCAACCCAAGGT NO: CCCGTTCATGAAACAGTGTATGATTTCTGGAGGATGATTTGGCAAGAACAATCTGCTTGCAT 1797 TGTGATGGTTACAAATTTAGTTGAGGTTGGCCGGGTTAAATGCTATAAATATTGGCCTGATG ATACTGAAGTTTA PTPRK ADXCRPDRC.14082.C1_s_at GGATTCACGGGTAGAGATTGGCTTCGGGCTGAGCTAGCAGTGAGCACCTTTTGGCCCAATGA SEQ ID ATATCAGGTAATATTTGAAGCTGAAGTCTCAGGAGGGAGAAGTGGTTATATTGCCATTGATG NO: ACATCCAAGTACTGAGTTATCCTTGTGATAAATCTCCTCATTTCCTCCCGTCTAGGGGATGT 1980 AGAGGTGAATGCAGGGCAAAACGCTACATTTCAGTGCATTGCCACAGGGAGAGATG PTPRK ADXCRSS.Hs#S2979568_at TGCTGTGTTAGCAACTGACGTACAATAAAGTTGAATTCACCCGAATATCTAAGTCTTAAAAG SEQ ID ATAAATGCAAGTAGCTGGTAGCTGATTTAGGCACCAGTAACAGAAGTGAACACCTAAAAAGT NO: AAATGCTATCACAGGTAGGAACATGTGAGTGACCCTGATTACTTGTCAGTAGGAAAAGATGT 2148 GGAGTGCAGGCATATTCTCTTTCTACTTTGGATCAGCAATCAGATTCACTCACAGATCATCG ATTC PTPRK ADXCRSS.Hs#S794492_at GACCTTATTATTTCTCAGTTTACATACCAATACTCTCCTATACATACACAATATACTAAGAG SEQ ID GAATACTGTTGTCTTCGTACCCAAATTACACATAAACAGATAAAAACTGACTTTTGCCATCC NO: CTTTGCAAATGTTGTAGCAAATTCTAATGTTCTCAGGCCACGCTGGTTCATGATCCGAGAAT 2190 CTGAGACAGTTATAGTCGAAATGTCATAGGAGGCAGGCGTGGTGGCTTGCCCTGTAATTCAG CACTTGGGAGGTCCCTTGGACGA PTPRK RDCR460_E08_at AGAAATATGCCTTGCCTTCAGAGAATTTATAGAAAGTCTATCTGTCAGTGCTAGGGTGCTAG SEQ ID GGGCTGGGAGGAGCTGAGAGCAGCTCTAAAGCCAGGAAGCTGGACCTAAAACAGATGGCTAT NO: TGAGCGAAGTATTTGAAGCTAGATGATGTGTAAGTAATAATATTCTCTGAGCACCTCTATTA 1370 TTATTTTTTAGGTTCTCTGCATCAGAATGAGGAAAGAGATTTAATAAGTTGTGAATTTTAAA TTCATGAGAATGCCAATAGAGACC PTRF ADXCRAD_AI282511_s_at CTTACTTGGGCAGAAATGTATTACTTATTGTGCCTATTTTCTTT SEQ ID NO: 2833 PTRF ADXCRAD_AL545542_at GCTCCTTCCCTAGGAGCATGGGTGGCACGTGCC SEQ ID NO: 2330 PTRF ADXCRAD_AL545542_x_at AGGGTGCCGGCCCTGCCACCAAGTTGAGAGCTGGAGGGGAGGTGGGGAGAGAACATCACAGA SEQ ID GCAGCCAGCCCTGGTTCACTCCTGGSAGTTTCTTCTCAAGCTCCTTCCCTAGGAGCATGGGT NO: GGCACGTGCCTGTTGGTCTCAGC 2331 PTRF ADXCRAD_BI869786_at GGTGTATCCCGGTATTTGGTGTACAAACAGTTGGTCCCATTATTGAAGTCGCACTTTTATAT SEQ ID ACACACATAGTACGATGTCAACCGTTGTTTTACACACCGCTGGAGATCGGGCAAAACACGCG NO: AACAGACACGGGGCGAAACCTCGGGCAGAAGCGCACCCCAACATCACAGAGGGGGCTGAACA 2642 CCAAGGCGCAAAACTCAACCATAAAGCGAGATTAAAGACAGACGAGGGCACAAAGTAAAACC TGTACACGCGCCAACACGGGACACAA PTRF ADXCRAD_BU186765_at TTCCATTGAACCCAAAGGTCCGCAACACCTGCCTCCCAGGCCTGGGGCGGAAAAAATTGAAA SEQ ID CACCTCCTCTCCACCTTGAATGGGAGCCTTCAAGGG NO: 2474 PTRF ADXCRAD_BU186765_x_at TCTACTAAGCCGAAACCCATCTCTACTAAAATTACCAAAATTTNCCTGGGCATGATTGCGCA SEQ ID TGCCTGTAAATCCAGCTACTTTTGGAGGCTTGAGGGGGGCAGCAATTGCTTGAACCTGGGGA NO: AGGGGGCAGGTTTCCATTGAACCCAAAGGTCCGCAACACCTGCCTCCCAGGCCTGGGGCGGA 2475 AAAAATTGAAACACCTCCTCTCCACCTTGAATGGGAGCCTTCAAG PTRF ADXCRPD.10702.C1_s_at GACAGAGCAGAATGAGCCCTCACCCTGGCTGGGGGTCCAGCACAGGCTGTATCTGCAGAGGG SEQ ID TCCCAGAGGAACGCTGGAGCCAAGAGAAGCCCTGGGAAGGAGGGGTGGGGAACGACATGCAT NO: GTGAGGGATGGCACACTGATGTGTTTATGCACCTGCACACAGGAGCGCATGGCCATGGCTT 1478 PTRF ADXCRPD.2246.C1_x_at TCTCCCCAGTCACAGCCTGAAGGGAGGCCCCGAGAGCTTCCTCCTTCCCCCCACCTGCTCCT SEQ ID TACCTTCTCTGCCCTGCTTTTTAGAACTGCAGTTCATTGTTTTAAGGGATTGGGGGAGGGAG NO: CCTGGGGACACAAACCTTTTATACAATACAAAGCTTTGCNNNNNNNNNNNNNNNNCTTCCCT 1917 TTTCCCNTTTCTCGGTTCTCTTTTCTCTCCTCTGGAATGGGCTGAAGACCCCTCTGCC PURA ADXCRAD_CD677455_at ACTGCTGCATGACTATCATCTTTGAGTGAAGAGAAA SEQ ID NO: 2621 PURA ADXCRAG_BC036087_s_at ATGCTAAGTGTATTTGTGTTCCCCAAGTGTACAAGCCTTCTATCAAAAGTATGTTCTATAAC SEQ ID TCATATATTCAAGGTGTAGGGTATGAAAATGCAAAGTTTAGGAGAGCACTTTACCAAGCTGG NO: TGTCCTCCAAACTGAAATTGTTTGTAACGATAGTCTTTTACAG 957 PURA ADXCRIH.2305.C1_at CGGAACTCGATGAGCCCCTGCGCGGGCAGCGCAATGGTCTGGCCCTGCGTGGAGCCCAGGCC SEQ ID AGGCCCCCGGTTGACCGTCTGGCGGATGCGCAGGAAGCGGCCGCGCTGGTTCTCCTTGAGAT NO: CCATGTAGTACTTGCGGTTCTCGCGCACCAGGAACTCGCTTTTGAGCGCCCGGCGCGGCTCG 1117 TCCTGCGCCTGGGCCAGGTCCGGCGGCTGGCTGGGGCCCAGCTGCGCGTAGTGCTCGATGAA GTCGCCCAGGTAGTCGCGGAACTCCACGGCCACTGACATGGAAAGA PURA ADXCRIH.2305.C1_x_at CGGAACTCGATGAGCCCCTGCGCGGGCAGCGCAATGGTCTGGCCCTGCGTGGAGCCCAGGCC SEQ ID AGGCCCCCGGTTGACCGTCTGGCGGATGCGCAGGAAGCGGCCGCGCTGGTTCTCCTTGAGAT NO: CCATGTAGTACTTGCGGTTCTCGCGCACCAGGAACTCGCTTTTGAGCGCCCGGCGCGGCTCG 1118 TCCTGCGCCTGGGCCAGGTCCGGCGGCTGGCTGGGGCCCAGCTGCGCGTAGTGCTCGATGAA GTCGCCCAGGTAGTCGCGGAACTCCACGGCCACTGACATGGAAAG PURA ADXCRIHRC.2305.C1_s_at ATGTGGGCTCCAACAAGTACGGCGTGTTTATGCGAGTGAGCGAGGTGAAGCCCACCTATCGC SEQ ID AACTCCATCACCGTGCCCTACAAGGTGTGGGCCAAGTTCGGACACACCTTCTGCAAGTACTC NO: GGAGGAGATGAAGAAGATTCAAGAGAAGCAGAGGGAGAAGCGGGCTGCCTGTGAGCAGCTTC 1308 ACCAGCAGCAACAGCAGCAGCAGGAGGAGACCGCCGCTGCCACCCTGCTACTGCAGGGTGAG QKI ADXCRAD_BM931336_s_at ATGTACTTAGAGCTTTTTGAGTGTAGAATTTTAAATGGCAGGATTTTACAGTGTTTACATGC SEQ ID AAGTGCATTTTATAAGTGTTCTATATGTGTAAAATAGTATTTTCAACTGGAAAGTGTTGGCT NO: AGTGCAAAAGGCCTGGCCATTTTCTGGTTCCCATGATGTTGCCTACACTGCTAGACTACAGT 1057 TTAGTATCGCTTTGTATCATGAGGCCAAGAAATTCCATGTTGTTT QKI ADXCRAD_BQ720286_at ACACTTTCAATTTTATTTGAGGCTTTCCACACTATTTAAAAGGAAAATGTAAGAAATTTGAC SEQ ID ATTCCTGGAGTTATTATAACCATTAGGAAAATGAGCCATAACATTCACCTCCTGATTTTTAC NO: CCATTTAAGGGGGAGAATTAAGTAAAACAGAACTGGCTTACAGGG 2634 QKI ADXCRAD_BQ720286_x_at TCTCAAGCCAACTGCAGCTGGAAAGTGCTGCTTATCCTCCACCCCCAGAAAATGCATGTATC SEQ ID AATATGAGAATAAAGAACGCACACTTTCAATTTTATTTGAGGCTTTCCACACTATTTAAAAG NO: GAAAATGTAAGAAATTTGACATTCCTGGAGTTATTATAACCATTAGGAAAATGAGCCATAAC 2635 ATTCACCTCCTGATTTTTACCCATTTAAGGGGGAGAATTAAGTAAAACAGAACTGGCTTACA GGG QKI ADXCRAD_BU508110_at CCATCTACCCCAACAAAAGACAAAGAAATTGTTGTCCTCCACTCAGCTTTTTTTTTTTTTTT SEQ ID CCTGTTTGGGGGAAGGTGGTCTAGAAACTGCACGTGATAGTAAGTAAAGCAATTAGGGCCCA NO: ATTCTCCCCACAGCCTGGATCATCTTTTAAATACCCACCCCAAGCCAACGGGAAAAAAGGCC 2319 TCCCTTTAAAAAGGGGAAAACAAAGGCCCTTACTTACCCCAAGGACAGAGGCCGTTATCGGT GAGAAACTT QKI ADXCRAD_BU508110_x_at AGCGAGCTGAGGCACTTGTCCGTTCGTCTTACCATCTACCCCAACAAAAGACAAAGAAATTG SEQ ID TTGTCCTCCACTCAGCTTTTTTTTTTTTTTTCCTGTTTGGGGGAAGGTGGTCTAGAAACTGC NO: ACGTGATAGTAAGTAAAGCAATTAGGGCCCAATTCTCCCCACAGCCTGGATCATCTTTTAAA 2320 TACCCACCCCAAGCCAACGGGAAAAAAGGCCTCCCTTTAAAAAGGGGAAAACAAAGGCCCTT ACTTACCCCAAGGACAGAGGCCGTTATCGGTGAGAAACTT QKI ADXCRAD_CK002286_s_at TTATACCTGGACATTTTAGATGTTTATCAAAGGTCTTTTATGGGGAAGAAAGTAAATGTATG SEQ ID AAATAATAAATGTGTGACATTTATAGGGAATGTTGGCTCTGAACAAACTTTTGAAAACTTGG NO: TTGACAAAATTTTGGATCAACTGAAAAAAGCATGACTTTTGAAATCTCTGAATGCCTTGGTT 2530 CTCAGTATTATCATT QKI ADXCRAD_CN295279_at ACAAGGTACATGCATTATGTGTCACATTACTGGGCAAACTGTTCAAGTATTTTTTTTTAAAC SEQ ID CTCCCTGTATAGAAAAAAATCATTAAGGATGTAAAAGCCATGCTTGCCTATTTGCTGTATAC NO: ATGTAATGAAATTGTAGATAAAGTGTAGTGCATTGAAACAAATGAACAAAAAGTAGATACTT 2728 TTACTATACAAGGGTGCTGGTGCAGAAAA QKI ADXCRAD_R41907_at CTGGACAACTTTTTAATGCTGTTTTACCNCAGNGAGAAAGCAATGAACAAAAGCATATTAAC SEQ ID ATATTATCATTTAATTAAAATGTATTCAAACCAACTTTCAACTTGTACTACCAGTATGTCTT NO: AATTTTATA 2868 QKI ADXCRAD_AA935633_at AAGTTTTCTGCCTCCACAATCTTTCAAATGCCAACACAAATAGGAAAAGCAGAACCCCTTAA SEQ ID AGGGACAGCTCAGGTTTTCTCTGGAGCAACTTGAAATTAACAGATTTGCTATTCCAACAGCG NO: GAAAATGCCCATTTCAACGTTGGTGAGTGCTGTATGTTTAACATACGGAAGCAAAACGACGA 2845 GAAAGCCGTAACACCTAACCATTTTCTACTTTTAAGTTGTTTCTATGACTTTCAAGACAACA GAACTCCTGGGATTTTT QKI ADXCRAG_AF142421_s_at AGCTGGCCCTACCATAATGCCTTTGATCAGACAAATACAGACCGCTGTCATGCCAAACGGAA SEQ ID CTCCTCACCCAACTGCTGCAATAGTTCCTCCAGGGCCCGAAGCTGGTTTAATCTATACACCC NO: TATGAGTACCCCTACACATTGGCACCAGCTACATCAATCCTTGAGTATCCTATTGAACCT 866 QKI ADXCRPD.17514.C1_at GAAAGTGTTGCCATGAGGGAAGAACTTAAGGGAGTTTAGAAAAGTAATGCGATGACGCAACT SEQ ID GTAACACTATGTTTAAAAGGATAGTGTCCTGGGTGAAATTACTGTTGCTTCTTTTACGCCAG NO: AA 1888 QKI ADXCRPD.17514.C1_x_at GCATCATGCATGAACCTTCGGGCAGGGATATCATTGGTGAAGTGATTTCAAAAAGTATTCAA SEQ ID AATTTGAGATGCTGTTTAGTCACTACAGTGCCCTCAAAGGGCAGAAGTTGCAGCCTTTTTTA NO: TATTGCCTGCCAAAATATGAAGTATTAGAAGAAAGTGTTGCCATGAGGGAAGAACTTAAGGG 1889 AGTTTAGAAAAGTAATGCGATGACGCAACTGTAACACTATGTTTAAAAGGATAGTGTCCTGG GTGAAATTACTGTTGCTTCTTTTACGCCAGAA QKI ADXCRPD.1932.C1_s_at GATACAAAATGCAAAATCCACAATTTTGATAAACTGAAAATTGCCAATTTGTTTTGCAGTAC SEQ ID TTTATTATATTGGGGTGGCCTTGTCCTTTTTGGGCTTTTAGTTAGCTAATGAATGAATACAT NO: TAGACACTTTTGGGTTTTAGTTGGGATTTTACATAGCTTGCATTTTAATTCTTTGGTTCTTT 1534 GCTGTTTCTATTAACCCACAGCATTAT RAB31 ADXCRAD_AL552789_s_at GACCGACTGGGTATCTAGCTTACTGTTTTAACATCATTGTTGAAACCAGACCCTGTAGTCCA SEQ ID GTGGTGCTGCCCTGTTGTGCAAACTGCTCCTTTTTCTCGTGTTTTTGTAAAGAGCTTCCATC NO: TGGGCTGGACCCAGTTCTTGCACATACAAGACACCGCTGCAGTCAGCTAGGACCTTTCCGCC 2580 ATGTATTCTATTCTGTAGTAAAGCATTTCCATCAACAATGCCTAATTGTATCTGTTATTTTT GGTTTAACACACACTGATTCATACT RAB31 ADXCRPD.1938.C1_s_at AGCCGCCGGTGCTGTTGACCCAAGGGCCGTGGTCCACGGTACTTGAAGAAGCCAGAGCCCAC SEQ ID ATCCTGTGCACTGCTGAAGGACCCTACGCTCGGTGGCCTGGCACCTCACTTTGAGAAGAGTG NO: AGCACACTGGCTTTGCATCCTGGAAGACCTGCAGGGGGCGGGGCAGGAAATGTACCTGAAAA 1535 GGATTTTAGAAAACCCTGGGAAAACCCACCACACCACCACAAAATGGCCTTTAGTGTATGAA ATGCACATGGA RAB31 ADXCRPD.2065.C1_at AATGCGCCGGCCTAACAATAGTTATAAAAAATTGGGGGGAGGACAACCTCCCCTTCCCCCTC SEQ ID CCGGATCCCCCGCCCGCCTTTTTTTTCCGCACTATTATCCGCCTCTGCCCCGCCGCCTCAGA NO: ATACCTCTATCCCGCCGCGGAGAAATTNATTCGCGCCCCGTATTTTCTGCCCGCCGCGAACA 1412 CGCCCGCCAACCAGTATTCTCGGGAAAATAATATAATGGGACTCAAAAACACCGCTCCCCGC CCAAATACGAACGTCGCGGTGGTTATTACTTCTCGCCC RAB31 ADXCRPD.2471.C1_at GGTTGTAAAGCCTCATTGTAGACAAGGCCTGAGCATCCACAGAGAAGATACAATGTTTATAT SEQ ID GAATCCTGGTGTGCCCAAGTGTGATCTACTCTCTTCACTGACTACTCTGAGTGCTGATGAGA NO: ATATATATATTATCCTCTGACTGGCTTGAATAGCTAAGACAATACAGAAAGGTAACAGAGTG 1496 GTTTCACACCCTCATGTGCTTCTGAAATAAAACCATGGGCTCATTAGTGGGTAGCTCACTAT CTGTGGCAA RAB31 ADXCRPD.8667.C1_s_at GATTGGATTAAAGACCTGGCACTTCAGTAACTCAGCACGCTTCCACTTCACTCAACTTAAGA SEQ ID GAGTTCATTGACAGTGTTAGGATGTGAAGGCTGGGAAACACTTATTTTGCTTCAAGAGTTCC NO: ACTTGGCTCTCCCAAATAGGTACCTCAAAAACTGTTAGCAAGCGGCATTTGGATGTCTTGAC 1406 AGGGGCTTTGCAGGGATTTTTAGGGTTTTTTCCACATTGTCCACATTAATGGTTGGCATGAT TGTGCTTGCAGGCCAAGAAATGATCATACCCCTTGCCAA RAB32 ADXCRPD.4345.C1_at TTTGTCATTGTTGCCATCATATGGAAGATAATGTTTACATCCTTTTAAACATTTTTATATGA SEQ ID CAATTCCTCAGGATTTGGTAAGGCTTCCAAGTTGTAGCTT NO: 1906 RAB32 ADXCRPD.4345.C1_s_at ATGTCATGTTAGCTGGGAGTCTTCCCACATGTGGCACTTCAAAAGGCAGCACCACTGGGCGC SEQ ID CTGCACTTATTTGAAAATGGAACTTTGGGAGAAGTATCCCTGCTAGTGGCTCTGTAACTTAA NO: CAGATGACAATTAGGCTTTT 1907 RND3 ADXCRPD.11316.C1_at TTCCACAAACTATGTCATCAGGCTCATTTTTCAAAACCAATGTGCACAACACCTGGTCAAAC SEQ ID TTCTGCGTCAACTACATTCCGTGTCAATAAAATGTTTGCTTTGCCAAGGGAGACTCTGAGAA NO: AGTGACCAATATGTAGCAACTGAGAAGTCATTTAAAGGACATCAGA 1472 RND3 ADXCRPD.1153.C1_s_at CACTCAGTTCTATGTCTTACAAGCACTTTGTCTTGTCTCTGCAAGAAAATTCGATTCCAGTC SEQ ID ATTTCCCATAAAATACAGACATTTTACCAACATAATATGCTTTGATTGATGCAGCATTATGC NO: TTTGGGCAGTATTACAAAATAGCTGGCGAGTGCTTTCTGTATTT 1868 ROBO1 ADXCRAG_NM_133631_s_at AGATAAGTATCAGGTCTGACCCCAGTGGAAAACAAAGCCAAACAAAACTGAACCACAAAAAA SEQ ID AAAGGCTGGTGTTCACCAAAACCAAACTTGTTCATTTAGATAATTTGAAAAAGTTCCATAGA NO: AAAGGCGTGCAGTACTAAGGGAACAATCCATGTGATTAATGTTTTCATTATGTTCATGTAAG 1051 AAGCCCCTTATTTTTAGCCATAATTTTGCATACTGAA 41889 ADXCRAD_AI831470_at ATTAAGTTTATCCTTTTCTCCATCTTTTCTTTCTTGCCACCTAATGAAGGAAATGTCTCCAA SEQ ID GGTCTTTTTGACTAATAGAAACTAAATGTATAACTCGACATCTAGAAGGGTTTCAAGATAGT NO: AGATATGTCTGCTGGGATGTTTTGTCATTACCCTGCCCAATGTTGCGACGCTAGGAGTTTCC 2805 TTGACACTACATTATAAATAAGGCCCAACCTGTTAGCAAAAATATCACATTCCCTAATTTTC TCTCCTTTAACTGTGTGTAATTTATCCAGGCATGTCTTTAGTTCAG 41889 ADXCRAD_BF855173_at AAGGTACTTAGAGCTCTTACTTTCTAAGTACAGAACACCCTAGACAATTCAAGGCATCTTAA SEQ ID TCTCCATCAAGAACAAAAAAAAAAATAATTTTGGTCATGCGGTTAAATCCATCATTAGGGAT NO: AAAACGGGTGCAAATGGGTCAAAGGGATCCAACAAACACGGATGTCCAAGCGGGCATATGGG 2333 CAACTATTACGTTAACGGGGGGTCAATAGAGAGTTAAAAAGATCTTCCCTTTCTTCTGGTTC TTTTCCAGGGTTCTGGAAGAGTTCTGGT 41889 ADXCRAD_N39126_at CAACAGAAAGATGGACTAAATATAAAGGGGGGAATTCCTGGACCTCCTTTGGGTGGCTAGAC SEQ ID TGGTANGTCATAGGCTAAGCCGGAAGGGTGG NO: 2855 41889 ADXCRAD_N39126_s_at AAACAAGTACAATATCCTGGCATAAAACTATCTTTCAGACAAAATCCACCTGCTGTGTATTA SEQ ID AAAAATGTAATACTTGAAAACTTCCTGCCTTGGGAGAGACTAAACCCGATTCATAATACAAA NO: 2856 41889 ADXCRIH.335.C3_s_at TTACACTTTATGGTAAGTAGCAGGGGGGGAAATGCATTTATAGATCATTTCTAGGCAAAATT SEQ ID GTGAAGCTAATGACCAACCTGTTTCTACCTATATGCAGTCTCTTTATTTTACTAGAAATGGG NO: AATCATGGCCTCTTGAAGAGAAAAAAGTCACCATTCTGCATTTAGCTGTAT 1260 41889 ADXCRPD.177.C1_s_at ATAAAGGACCGTTTACCTCTTGCTGTGGTAGGTAGTAATACTATCATTGAAGTTAATGGCAA SEQ ID AAGGGTCAGAGGAAGGCAGTATCCTTGGGGTGTTGCTGAAGTTGAAAATGGTGAACATTGTG NO: ATTTTACAATCCTAAGAAATATGTTGATAAGAACACACATGCAGGACTTGAAAGATGTTACT 1905 AATAATGTCCACTATGAGAACT 41889 ADXCRSS.Hs#S1914581_at GGGCCCAGAGTTTGCTCCCAGGGAATCTAATGAACCACCTGGAATCAAACATTTGGAGAGAA SEQ ID GGCCAGTCACTTTTATCGGAACGTCAGATGGTCATGGACCCTCAAGAATGATTGAAGAAATT NO: TGTAAGCCCAGTTAAAACATCCACAGTCTTCTTTCCTCAGTGCAAAAGTTGCCCTTTTTGAT 2088 ATCTCATATTTAGAGTAAAAAAATTTCGTTAATAAGAGATCCTCT SCRN1 ADXCRAD_CK001870_at AGATGGAAATGCTATTGGCGGGAATATATAAAAAAAAAGAATCTTCTGTTCTGCATGG SEQ ID NO: 2046 SCRN1 ADXCRAD_CK001870_s_at GAGCAGCAGGTCATGTGCACATGCCGTTGCAGCACAAGCTTATGCTTCCCGTAGCCGTGGCT SEQ ID TTTCATTCTGCACAGTCCCAGGTCCCAGCTCCCCTCTTATGGTTTCTGTCATAATGTGCTTT NO: ATCTGATTGACTCCAAACATCCCGAAATGTCACCTGCAGATTTCTCGTGGGAACCAATATGT 2047 ACATGTT SCRN1 ADXCRIH.243.C1_at ATAATCGAAATTATGGAGGTTCCTTAGTGCTCAATAATATAAGACCTGTTGTTATTAGAACG SEQ ID AGTCTTTCTTATAAACTAACAGAGCAGGTATATGCCTGTTAGATCTTAGCTGTGGGGTTCCT NO: TTACTATTGGGTGAATCATTAGGTATAAAAAATAATCATCAACCAGGCCAAATACTTTGCTT 1256 CCTAGCTGATGTCATCCCACATTGGTACAGTGTTATTCATTACTGGGTGGTTCAACAGGGAA GCCAGTGGGA SCRN1 ADXCRIH.243.C1_s_at GGTTCCTTTACTATTGGGTGAATCATTAGGTATAAAAAATAATCATCAACCAGGCCAAATAC SEQ ID TTTGCTTCCTAGCTGATGTCATCCCACATTGGTACAGTGTTATTCATTACTGGGTGGTTCAA NO: CAGGGAAGCCAGTGGGACCAGTGTGTCTGTCATGAAAC 1257 SCRN1 ADXCRPD.2301.C1_at CACGTGCTTCCTTACTAAGGCTGAGAGCTCAACTGAAGACCTTCCCCAATAAATGACAGATG SEQ ID GCTCTTCAGTCAGGAATGCAGTTAGTGGTTTCATGACAGACACACTGGTCCCACCTGGCTTC NO: CCTGCTGAACCACCCAGTACTGAATAACACCTGTACCAATGTGGGATGACATCAGCTAGGAA 1899 GCAAAGTAATTTGCCTGGTTGATGATTATTTTTTATACCTAATGATTCACCCAATAGTAAAG GAACCCCACAGCTAAGATC SNAPC1 ADXCRPD.2725.C1_at GAAAGAATCCATCCTTAAAGTCAAAAACTAATGATGGAGAAGAAAAAATGGAAGGAAATACA SEQ ID CAAGAAACGGAGAGATGTGAAAGGGCAGAATCATTAGCGAAAATAAAATCAAAGGCCTTTTC NO: AGTTGTCATACAGGCATCCAAATCAAGAAGGCATCATCAAGTCAAACTCGACTCTTCGGACT 1555 CTGATTCTGCATCTGGTCAAGGCAAGTCAAAGCAACTAGGAAAAAAGAGAAGAAAGAAAGAG TGAAACCAGCAGGAAGGAAGATGTCTCTCTAGAATAATAC SPTAN1 ADXCRAD_CA435088_s_at AATTGATTTCTATTTGCCATTCTCCAAAAGACAAAAAAAGTTGGTTTTTTTTTTTTTCGGTC SEQ ID TTTTGTTTGTTTGTTTGTTTTTTAAAAAATAGGGTCTTGCTTTGTTGCCCAAACTGGAGGTC NO: AGTGGCTTTTCACAGCTGCAGTTATAGCCTACTGCA 2571 SPTAN1 ADXCRPD.3100.C1_s_at TCCGGTCCAGTCACAATCATCATGTCACTGTGGGGACCCAGATCTGTGTCTTGAAGCAGCTG SEQ ID CCCTCATTCCGACTTCAGAAAATCGAAGCAGCTGGCTCCTCC NO: 2277 SPTAN1 ADXCRPD.9848.C1_at TCAGTTCAACTGAGCGACGTGTATACTCCTGGGCGTGAAACAG SEQ ID NO: 2293 SPTAN1 ADXCRPD.9848.C1_s_at AAGATTATGGCGACACTCTTGCCGCCATCCAGGGCTTACTGAAGAAACATGAAGCTTTTGAG SEQ ID ACAGACTTCACCGTCCACAAGGATCGCGTGAATGATGTCTGCACCAATGGACAAGACCTCAT NO: TAAGAAGAACAATCACCATGAGGAGAACATCTCTTCAAAGATGAAGGGCCTGAACGGGAAAG 2294 TGTCAGACCTGGAGAAAGCTGCAGCCCAGAGAAAGGCGAAGCTGGATGAGAACTCGGCCTTC CTTCAGTTCAA SPTAN1 ADXCRPD.9848.C2_at GAGGAGAACGACAAACTGCGCCAGGAGTTTGCCCAGCACGCCAACGCCTTCCACCAGTGGAT SEQ ID CCAAGAGACCAGGACATACCTCCTCGATGGGTCCTGTATGGTGGAAGAGTCGGGGACCCTCG NO: AATCCCAGCTTGAAGCTACCAACGCAAGCACCAGGAAATCCGAGCCATGAGAAGTCAGCTCA 2295 AAAAGATCGAGGACCTGGGCCGCCATGGAGGAGCCCTCATCCTGGACA STK17A ADXCRAD_AW183478_at GAAATTCAACAATGAGCATCTGTCCTTCCTCTATACCACTACTAGAGAAAGGGATTAATTAC SEQ ID CTCCTAGTTTTCATTTGAAAACAACAAAACACAAGATCAATCAAATATCATTTCCCAGTTGA NO: TTAAAACTTATACATTTTATACATTTCATAAACAACGTTTCACCACACCAAAATATTGTTGA 2801 ATTATAGTTAAAACTGGATTTATAAACCGAGTAAACTCAATAGTACTGGTTAGTCCTTTATA AATTTGGGGATAGAAAAAAAGGAACATTAACAGCTTTAGATAAG STK17A ADXCRAD_BQ227453_s_at AACTTTGTCAAATTTGTGGAGTTAGGTGGAAGCCAGATTTTAAAAGTTGCCAACCAGGATAT SEQ ID TTAACAGGTACAGTTACCCGTTTCAATGTTATTTTTAAGAAGGGAGATGTTGGCACCTTTGA NO: ATTCTACATCCTGTTTCTC 2617 STK17A ADXCRAD_AA234664_at AAGTGAGTAAAATCCCCTAGAGCAGAGAGAGAGAGAGAGAGAGAGAGTGTCTTCATGCCAAC SEQ ID CACAGCCTGTTTCTGCTGAGTTTCTTATCAGCCCTCAAGCTATGCTAGGAAAAGTTATAAAA NO: TGCCAAAATATTTATAAACATTTACTTTGTCCATAAAATATTTACATTGGATACTCTGTAAG 2398 TAGGAGGTACTTTGTCCCAAAAAGATGTATAAGAATGTACTAATAGTTTTATTTGATTAGGA TTGAACAGTTCAGTTGTATCTATGCCCCACAGTGACCAGTAAAGT STK17A ADXCRPD.362.C1_at GCCGACCGGCGCACATGTGATAAGAAGATACTGTGGGGTGGCCCCCCCTTGCGGCCCCCCAG SEQ ID AAAGAAATCTTTTTAAAACCCCCTTTTTCTTTTTTGGGCGGCCGCGGGGGCGCCCCCCCGAT NO: AGGGGACAAGGCCGGGATACGGGGGGCTCGAAACCGTTGTGGCCCCTTCCACAGAGGAAAGA 1909 TACCCGGTGGCCACCCGGATAAATAACCGCGGCCTGTGTGTTT STK17A ADXCRPD.7382.C1_at AACGACTTATGCGACCAGATTTTAGAAGGTGTACACTATTTTACAACACTCGTGACTGTAGT SEQ ID TCATCTGGCATTTGAAGCCTCAGGAATATTCTGGTGAACCAGTGAATCTCCATTGGGTGACA NO: TTACCGATCGCAGATTTGGGCTACCCAAGACTATTGAAGACCAGTGAAGAGCTCGAGGAACA 1784 TCATGGGTAACCCTGAATATGTGGGTCCGGACATCCTAAGTTATGATCCTCATAGCCATGCC ACA SVIL ADXCRAD_CA396083_s_at GAAGCTTGAGATCTATCTCACCGACGAAGACTTCGAGTTTGCACTAGACATGACGAGGGATG SEQ ID AATACAACGCCCTGCCCGCCTGGAAGCAGGTGAACCTGAAGAAAGCAAAAGGCCTGTTCTGA NO: GTGGGGAGACGCCAGAGGAGCCTCACGGTCACGTCCAACAACACCACTGCACCAGGGAAATG 846 GATAT SVIL ADXCRAD_CN402078_s_at GTATCTTCATACACGTTTGGAAATGTTTCCTGCAGCATTAGGTATGACTTGTTCTGAGTACT SEQ ID GCTTCCGGTGCTAAAATGAACAAAGAATTTGTACTTAATGGCATGGACTCTGGAGAATCTAT NO: GCGAATCAACCTTTCTACCTTAATATCTCCCCAAAAATGTATAGTGCCTTGTTTTTATGTAC 1315 AGTTTATATACAGAAAAGTTTGCTCTGCATTTTTGATGATGGTTTGGAACATTATCTACAAT SVIL ADXCRIH.3823.C1_at GGCATTGCCTAGCTGGAACAAGAAGGCAGTGCTATCTATAGCAGCTGCGGCTTAAGTGCACA SEQ ID TAACAGATACTTTTATTAATTCTGATAACCTCCTGAATGGTGGAAAGAAGTTTCCAAACAGT NO: TCCCTTGAACATTTACAAAATACACAACTCCGGGACAGCAGTATCTTTAACAATGTCATGTT 1176 CTGAAAACTCTGAT SVIL ADXCRIHRC.3823.C1_at ACCGGTTGTAAAAACAGTACACATGTCATTTTGTGATATAGGACTCCCAAATAAAAGTATCA SEQ ID GAATAAACACCTCGTGC NO: 1314 SVIL ADXCRPD.12020.C1_s_at GCTTCTGGGTGGCCAAACCAGTTACCCAATCTGCTGGAGACCCAAAAGAAGATGAACTCTAT SEQ ID GAAGCAGCCATAATAGAAACTAACTGCATTTACCGTCTCATGGATGACAAACTTGTTCCTGA NO: TGACGACTACTGGGGGAAAATTCCGAAGTGCTCCCTTCTGCAACCCAAAGAGGTACTGGTGT 1489 ATGATTTTGGTAGTGAAGTTTACGTATGGCATGGGAAAGAAGTCACATTAGCACAACGAAA SVIL ADXCRPD.9920.C1_at GTGAGTCAAGAAGGCCCTCCCCTGTCGGCGTTTGATCTCTCCAGCAGCAAACATCGCACATG SEQ ID GATTCTTGCAGAGCTTCTCCTGCGGCTGTTCCGAAGAATCCTGGGGCTTCCAGGACACGGGG NO: GCTGTGGTTTAAGCAATAGTTTTCCCAGCAGCTGTCCCCGTCTGCTCGGAAGTGGGCTCCCC 1551 GAACTCTGCCGCTCTTAGTGAAAACTTCCTTTTCATAACATTCTCCACCTCCACCTTCTCTT CAAAGGGCAGCCTGTCCTCAAGTC SVIL ADXCRPDRC.9920.C1_at CATGTCTATAAAGAAAGATGGCACTGTTGAAGAAAAGCGGGGAGGAAGATTGGAGAAACAGA SEQ ID CTCAGCAGGAGGCAGGAGGGCGGCAGCGCCGCCACAGCCGCACACCCAGAAGCAGGCGTCCC NO: TCATCAGAAGCGT 1963 SVIL ADXCRPDRC.9920.C1_s_at TGGAAGCCCCAGGATTCTTCGGAACAGCCGCAGGAGAAGCTCTGCAAGAATCCATGTGCGAT SEQ ID GTTTGCTGCTGGAGAGATCAAACGCCGACAGGGGAGGGCCTTCTTGACTCACCCAGCAA NO: 1964 TFE3 ADXCRPD.14170.C1_at CCTTTTGAAGGCACGGCAGAACGAAAGACATCAACAACCTTAATTTGAGCGTCGCAAGGCGA SEQ ID TTCCAACATTTACCGACAGGAATCAGGGAACTGGGGCCTCCTCATCCTAGTCCAGTGACCGG NO: AGA 1660 TFE3 ADXCRPD.2523.C1_s_at TTATTGCTCCGCATACTGAGAATCTAGGCCACCCCAACCTCTGTTCCCCACCCAGTTCTTCA SEQ ID TTTGGAGGAATCACCCCA NO: 1520 THY1 ADXCRAD_BM704951_at CTGGAATCTGTCCTCGTGTCCACCTGGCCTTCGCTCCTCCAGCAGTGCCTGCCTGCCCCCGC SEQ ID TTCGCTGGGGTCTCCACGGGTGAGGCTGGGGAACGCCACCTCTTCCTCTTCCCTGACTTCTC NO: CCCAACCACTTAGTANCAACGCTACCCCAGGGGCTAATGACTGCACACTGGGC 2556 THY1 ADXCRAD_BM704951_x_at GTTCTTCCTGTTCTGTGACTGTGTATAGTGCCACCACAGCTTATGGCATCTCATTGAGGACA SEQ ID AAGAAAACTGCACAATAAAACCAAGCCTCTGGAATCTGTCCTCGTGTCCACCTGGCCTTCGC NO: TCCTCCAGCAGTGCCTGCCTGCCCCCGCTTCGCTGGGGTCTCCACGGGTGAGGCTGGGGAAC 2557 GCCACCTCTTCCTCTTCCCTGACTTCTCCCCAACCACTTAGTANCAACGCTACCCCAGGGGC TAATGACTGCACACTGGGCTTCTTTTCAGAATGACCCTAACAAGACACAT THY1 ADXCRPD.3397.C1_at AAAGAGCACGTGCTTCTTTGTCTCACGGGTCAGGCTGAACTCGTACTGGATGGGTGAACTGC SEQ ID TGGTATTCTCATGGCGGCAGTCCAGACGAAGGCTCTGGTCCACTAGGCAGGCCGTTAGGCTG NO: GTCACCTTCTGCCCTCGGGAGACCTGCAAGACTGTTAGCAGGAGAGCGATGCTGATGGCCAG 1904 GCTCATGGTTCTGGGATCTCAGTCCTGGATCTGGACTGGGTCTTCCGCTG THY1 ADXCRPDRC.3397.C1_s_at CATCCTTGCCCATCGGGACCAGAAACCTGGGAGAGACTTGGATGAGGAGTGGTTGGGCTGTG SEQ ID CCTGGGCCTAGCACGGACATGGTCTGTCCTGACAGCACTCCTCGGCAGGCATGGCTGGTGCC NO: TGAAGACCCCAGATGTGAGGGCACCACCAAGAATTTGTGGCCTACCTTGTGAGGGAGAGAAC 2049 TGAGCATCTCCAGCATTCT TIMP2 ADXCRPD.1038.C1_s_at ACTTGCTGCCGTAATTTAAAGCTCTGTTGATTTTGTTTCCGTTTGGATTTTTGGGGGAGGGG SEQ ID AGCACTGTGTTTATGCTGGAATATGAAGTCTGAGACCTTCCGGTGCTGGGAACACACAAGAG NO: TTGTTGAAAGTTGACAAGCAGACTGCGCATGTCTCTGATGCTTTGTATCATTCTTGAGCAAT 1841 CGCTCGGTCCGTGGACAATAA TMEM158 ADXCRPD.7689.C1_at AACAAATACACAGGATTTGGTCATTTTCTGCCATGAATCTAGGGCACGTGGGTGCCGGGAAG SEQ ID GAGTCGGGCAGGGGGATGCAATAGAGGGGAAAGGGCCCCATTTCCCTCCTCTCCGTCTTCGG NO: AGCTGCGATCCCACCCTCAGTCCAAGGGCTTAAACATCTGCTTTTCGGAACTGGAAGCGCAG 1836 CACAAACCTTG TMEM158 ADXCRPD.7689.C1_x_at AACAAATACACAGGATTTGGTCATTTTCTGCCATGAATCTAGGGCACGTGGGTGCCGGGAAG SEQ ID GAGTCGGGCAGGGGGATGCAATAGAGGGGAAAGGGCCCCATTTCCCTCCTCTCCGTCTTCGG NO: AGCTGCGATCCCACCCTCAGTCCAAGGGCTTAAACATCTGCTTTTCGGAACTGGAAGCGCAG 1837 CACAAACCTTGCTTTTCAAAGGCGCTGGG TMEM158 ADXCRPDRC.7689.C1_s_at GATTAAATTGCTATTGCTGTAGTAAGAGAAGCTCTTTGTATCTGAACATAGTTGTATTTGAA SEQ ID ATTTGTGGTTTTTTAATTTATTTAAAATTGGGGGGAGGGCATGGGAAGGATTTAACACCGAT NO: ATATTGTTACCGCTGAAAATGAACTTTATGAACCTTTTCCAAGTTGATCTATCCAGTGACGT 2034 GGCCTGGTGGGCGTTTCTTCTTGTACT TRAM2 ADXCRAD_BM700086_s_at AGGCTGTGTCATTGGCAGGGCTTCACATGCAGGAGGCCTCTCTCAGGTGAGTCCAGGTTAAA SEQ ID CTGTTGAGTTGTGGCTTCAACAGATATGTATGGCATGCTGGGATGTGCCAGGTGCCTGCGTT NO: GTGCCAGTTGCTGGAGAGGTAGTGTGAGCAGAGCAGCTGAAATCTTGCCATCAAGCAACCCT 2739 CATTCTCATGCCTGTAGGTTTCCATTGCTCTGTCCCAGGACACTTGCGTGCCAGAGACGCCA CAACTTCATGTCCCTGTCTCTTGCAA TRAM2 ADXCRAD_BM789115_s_at TGGTGCCCTGAGCAACTGATAATGCAAATGTGGACAAAGTGTCTGTTTTCTACTCTAGCCTG SEQ ID TTCATATGGACCAAATTTCAACAAGGAACTCAAGGAAAATTTGTACCTGCCGTATTTATGCT NO: TTCATGTAAAAAAGGGTTGGGGGGAGGGGTGTCTTTTTGCTTTTGGTGAACTTTTTTTCAAA 988 ATCATTTTTCCACTGTTTCTGTCTGGTTTTAAAACAAATTACAGTTTTGTATGGATTTT TRIB2 ADXCRAD_CX783483_at ATCCTGGTCAGGAAATGACATGTTAATGCTTTGCTC SEQ ID NO: 2393 TRIB2 ADXCRAD_CX783483_s_at ACACATCCTGGCATCGCACTGTTAGCATTTAATTTCTTGTTAGGATTCAGGGAAGGAACAGT SEQ ID TGGCCAAGAATTTTTTTTCTTTTAAACAAGCCAACCACCTAGCTGGTAATTAATGAGGTTCA NO: CTTAAAAAAAAAATTCGGTGCACACAGACTGACATGAAACCTGGGTGCTACAGTAAAAGAAA 2394 ACAAAAGTCCAGTTTGTGTCTCTTAATCGCTCACTTCAACTCATTTCTTCTAAA TRIB2 ADXCRPD.1189.C1_s_at GGCTTCACCCTTCGTAACCAGGAGACAAGGCGGCCATGGATTTGCCCTTGATTCTATTTTGC SEQ ID TAATGGAAGATAGAAAGGAGAGAAGGNNNNNNNNNNNNNNAACATTCTGAAGATGGTGCTGT NO: GTCAAGAAGGACCTTTTTTTTCCCCTCTCCCCTATTTTTTAAGTACCTTGGAGGAGGAGAGG 1870 TTGGTGACATGCATGGTGGGGATCTATGGCCTC TUBB ADXCRAD_CX872111_at AACATGAACGACCTCGTCTCTGAGTATCAGCAG SEQ ID NO: 2481 TUBB ADXCRAD_CX872111_s_at GTATCAGCAGTACCAGGATGCCACCGCAGAAGAGGAGGAGGATTTCGGTGAGGAGGCCGAAG SEQ ID AGGAGGCCTAAGGCAGAGCCCCCATCACCTCAGGCTTCTCAGTTCCCTTAGCCGTCTTACTC NO: AACTGCCCCTTTCCTCTCCCTCAGAATTTGTGTTTGCTG 2482 TUBB ADXCRIH.194.C3_at TCCAGAAACGTCTTCTTAATCCCCACCTTTTCTTACTCCCAAAAAAGAATGAACACCCCTGA SEQ ID CTCTGGAATGGTGTATACTGCCACATCAGTGTTTGAGTCAGTCCCCAGAAGAGAGGGGAACC NO: CTCCTCCATCTTTTTTGCAACATCTCATTTCTTCCTTTTGCTGTTGCTTCCCCCCTCACACA 1261 CTTGGTTTTGTTCTATCCTACATTTGAGATTTC TUBB ADXCRIH.194.C3_x_at TCCAGAAACGTCTTCTTAATCCCCACCTTTTCTTACTCCCAAAAAAGAATGAACACCCCTGA SEQ ID CTCTGGAATGGTGTATACTGCCACATCAGTGTTTGAGTCAGTCCCCAGAAGAGAGGGGAACC NO: CTCCTCCATCTTTTTTGCAACATCTCATTTCTTCCTTTTGCTGTTGCTTCCCCCCTCACACA 1262 CTTGGTTTTGTTCTATCCTACATTTGAGATTTCTATTTTGTGTTGAACTTGCTGCTTTTTTT CATATTGAAAAGATGACATCGCCCCAAGAGCCAAAAA ULK2 ADXCRAD_BP319713_at GAGCTTTTCCATTTGGTGCTCCAATGTCTCCTGCTGGACCCATCTGCCTAGTGGAAGGCAGC SEQ ID AAAATTTCAAGAAACAGGTGAGGTTGAGCAGCTTGGTGCAACCCCATGGG NO: 2317 ULK2 ADXCRAD_BP319713_x_at AGAGAAGACTGTCGGCGCTCTGCCATAGCACCGCAACCGTGTGAGCAGCAGGCTCATCCCGT SEQ ID GGACCGGTGGTGGGAACGTGAGGAAGAGGGGAAGGAAGGAAGAGCTTTTCCATTTGGTGCTC NO: CAATGTCTCCTGCTGGACCCATCTGCCTAGTGGAAGGCAGCAAAATTTCAAGAAACAGGTGA 2318 GGTTGAGCAGCTTGGTGCAACCCCATGGGGCCCTGGAGTTGGAGCTCAACAGCAATGGATTT CAGA ULK2 ADXCRAD_CK818454_s_at AGTTGGTGACCTAAAGGCTTGTTAGTGATGTGGAGTTCCTACATGCAGTGAGTGGAAAATGA SEQ ID AGTTCGTTTTCTCTTAGGAAAATGGGCAGCTGTCTTCTGCCTAATGTGTATTTTTCATGTTA NO: ATTCTGACAGTTCACCAAATAGCTAGTCATGGAGAATGCAGGCAGTTAACTTAATATCCCTC 2421 CAGGAATGGTTCCTACGTTGTGTATTATTTGGTTTCTTTTACTTACCTGCTTGAATACT ULK2 ADXCRAD_NM_014683_at AAGTGATTGGCCTAAAGTCAGGAACTAGGCAAGTGGTCAAGCCATGCTTTGTGACTTTCAAG SEQ ID TTAATTCTTCTTGTTCTTGTATATTAAAGGTCTTGGGGTAGATGGTGTGTGTGAAACAGTGA NO: AGTCTCAACAGCAGAAAAGAACAAAATGTAAATTCATGAATAATGGTTCTGGTTATACTTCC 2771 ATTATCAAGGCTAATTAAGAGATTTTGCCTTGAGTATAGCAATAATAAACAAATGCTTTATG TTTCCCT USP33 ADXCRAD_BP275873_s_at GAAGACCTGGTTTTGATGCTGCCTCAGAACATTTGGGATAACCTATATAGCAGGTATGGTGG SEQ ID AGGACCAGCTGTCAACCATCTGTACATTTGTCATACTTGCCAAATTGAGGCGGAGAAAATTG NO: AAAAAAGAAGAAAAACTGAATTGGAAATTTTTATTCGGCTTAACAGAGCGTTCCAAAAAGAG 2569 GACTCTCCAGCTACTTTTTATTGCATCAGTATGCAGTGGTTTAGAGAATGGGAAGTTTTGTG AAGGGTAAAGATGGAGATCCTCCAGGTCCTATTGA USP33 ADXCRAG_AF383172_s_at CATGAAGTGTGGAATGTGTCACTACGATTGTTGATAAAGCTGAGGCCACTTGCAACTTGATT SEQ ID TTTTAAATGAAATAGATAAAGTCTTTTTGAATAATATAGTATGCACTGCTATTTGCTTGATT NO: ATGTAATGTCAAAAGTTTAACTATATTCCAAGTACAAAAACATACTGGATTACATTGAGGAT 876 GTTGAATAGCATTCATGATGGCTTTGTTTTGGTTTGGGGCAGCTGTCACCAGCTAAAGCAA TG VIM ADXCRAD_AL046837_s_at TTTTAAACTTGGCTGTATTGTGTACAACTATTATACCATCTTTTATAAACACAGTTTTTTAA SEQ ID GAAATTTCTTTTTGTAAGTTACAACATTCCACTGGATCCTTATATTGCCTGTAGTGGAAGAG NO: GGTCTTGTGTGTCTGCCCCTTCTAGTTTTCACTCATGCAGAAGCAACATAACCTTCTGATTT 953 GCACAATAAATNACATATATTTAGCAGGATTTTTATTTGCCGTGATATATAGGATAATTTAG TCTTTGGCATGTGGC VIM ADXCRAD_CX873552_s_at AAGCAGGAGTCCACTGAGTACCGGAGACAGGTGCAGTCCCTCACCTGTGAAGTGGATGCCCT SEQ ID TAAAGGAACCAATGAGTCCCTGGAACGCCAGATGCGTGAAATGGAAGAGAACTTTGCCGTTG NO: AAGCTGCTAACTACCAAGACACTATTGGCCGCCTGCAGGATGAGATTCAGAATATGAAGGAG 1312 GAAATGGCTCGTCACCTTCGTGAATACCAAGACCTGCTCAATGTTAAGATGGCCCTTGACAT TGAGATTGC VIM ADXCRIH.436.C1_at TATTCTGAATCTCATCCTGCAGGCGGCCAATAGTGTCTTGGTAGTTAGCAGCTTCAACGGCA SEQ ID AAGTTCTCTTCCATTTCACGCATCTGGCGTTCCAGGGACTCATTGGTTCCTTTAAGGGCATC NO: CACTTCACAGGTGAGGGACTGCACCTGTCTCCGGTACTCAGTGGACTCCTGCTTTGCCTGGC 1159 GCAGGGCGTCATTGTTCCGGTTGGCAGCCTCAGAGAGTCAGCAAACTTGGATTTCCTCTTCG TGGAGTTTCTTCAAAAGGCAATCTCTTCTTGCAAAGAT ZNF331 ADXCRAD_AW959541_s_at TCATGCCACCCACTCTACCAGTTGTCCCCACCATCCCCCGCCCTCCTTCCTGTGAGACACTG SEQ ID GGCCAAAGGCTCACTACCCCTGTGCGTTGTCCAGCACACAGACACTATGTGCATTATTTGTA NO: CATAAGGATAATCACATCTACCTGAGACTGCTATCATG 2447 ZNF331 ADXCRAD_BU176917_at TAAGTCTCGAATGGTGTGGCCCTTCTGAGTAGCGTGATGAAATCTCTCGCTGTCCGGGTCCA SEQ ID CCCGGCCGGGGATGTGAGTCATCCCCTTGGTCCAGCACATCCACGCTGTATACACCACCCAC NO: CCTGGTAGTGACTTAGTAACCGGCCTTGGTGATCAGGGATCAACTATGCCAACATCCGCAGT 2683 GCCCTGTGGCCCAAAGCAGGGCCTCACGTTTGGCTTTAACGGGGGGGCCCCAGGGGAGGCCA GGAATAGGGGGATTGCCTGGGTGGATTCCAGAATA AAK1 ADXCRAD_BP360257_at GGCAACACCTCGGCCCTGGGCAGGGGCTACATTGGAAAAATCTTCGGCATGGGGCGAAAGAA SEQ ID GGTCACAGTGAACAAGGGGTTGGCGAAA NO: 2628 AAK1 ADXCRAD_BP360257_x_at TCCTCTCCGAGGTGAAATCTGAGAAGAAATCCTTGGATCTCTTTTCTTAAAAAAAAAAAAAA SEQ ID AAAAAAAACTTCTGAAACCCAGGGGGTTTTGGCTTGGCGGCCCCCTATCCCCAAAAAAAAAA NO: AGTTTTTCAACTCCCGGGAAAACCAGGGGGGTTTTGGCCTGGGCTCCGGCTCCAGGGGGGGA 2629 GGGGGCAACACCTCGGCCCTGGGCAGGGGCTACATTGGAAAAATCTTCGGCATGGGGCGAAA GAAGGTCACAGTGAACAAGGGGTTGGCGAAAGGGGGATTGGCTATTGAATT AAK1 ADXCRAG_AB028971_s_at TGCTGAGCGGCTTATGTTCTGAATTTGTTTATGAGAACTGATCATTAGTGAGACTGGCCACA SEQ ID GTATTTAACCTTGCACATGCATGCTCAGTGAAGCCTAGACATTCAGAGCAGCAGAAATAAAG NO: TAACTTATTTTTCTTTCCACCTTGCCTGAGACTGGCATTTTAGAGACCTGTTAA 836 AAK1 ADXCRAG_NM_014911_s_at GAAGCCAAGGCTATTTAATCTCACTTGTATCACTCCAAATGAAGTGTTTTCCTTGCTTTTCG SEQ ID GGGGTACAACGTCTATTTTTTGCCTTTCTTGATATCTGGAGATTTCTAGAGTGGATCTCTTA NO: TGAATGAGGAGGAATGTGGAAAGTTTCACATTTAGTTAGAAGAACTTTAAAAAATTGGTTTC 1044 TAACTAGACTACCTTTACTGAACTTAATGAAATTTAGCAGATTCTTCTT AAK1 ADXCRAG_XM_371497_x_at CACTCTGGGAGGCTGTGTTGGGCCGATCGCTTGAGCTCATGAGTTCAAGACCAACCTGGGCA SEQ ID ACATGGCAAAACCTTGTCTCTACAAAAAATACAAAAATTAGCCAGGCATGGTGGTGCACACC NO: TGTAGTCCCAGCTACTTGGGAGGCTTAGGTGGGAGGATGGCTTGAGCACGGGAGGCAGAGGT 1090 TGCACTAAGCCAAGATCGTGTCACTGCACTCCAGCCCAGGCAATAGAGCCAGACCCTGT AAK1 ADXCRPD.17316.C1_at TCTTCTGCAGCTTTATGGACTGGAGCAGAGATTGCTGTGGGGGCAAACTCTTCCAGAAGGTC SEQ ID AGTAGTAGGGTTAGAGAGCAGAGAGCAATCAAGCAGGGAATCTTCCCCGGTGAGAGAATCTG NO: TGCGATTCGAGGTCACAGATTCCGTCTGAGATGGGAGGCGCTGGGGAACTGGGGGCTCCAGT 1848 CCTGGTATGAGACTCTCAACAGCAACATCAGCTTTTTCTTTCGTAACAGAGCATT AAK1 ADXCRPDRC.17316.C1_at AGGTGGGCACTCTAGAAACAGCAGTGGGAGCTCTGAGTCCAGTCTTCCCAACCTAGCCAGGT SEQ ID CTTTACTGCTGGTGGATCAGCTCATAGACCTGTAGCCGTGACCCAGTAGCAGATGCAGTTCT NO: GTAACCTTCATACCGTAAAATACATTTTCATTACGGAGTTATG 2036 AAK1 RDCR092_B07_s_at AACTCCCTCTGCTGACTATTTGGAATGGACTGAATGAGGAGGTCTCTCCAGCCAGAAGGAGT SEQ ID ATTGAGGTCATCAGGCCTCAGAAAACAATGTACACATAATCTCGGGCTGTGAACAAGAGAAA NO: GGAGGGGGGGAAACATGAAAGTCAATCTTAACAATTTTTGCAATACCTCTTATTTGCAGACC 1363 ATTGGATTTATGTTATTGCACTCTCGGTGTGATTTATCGTATGTATCTGAT

TABLE 9 Genes and corresponding Almac probesets predicting sensitivity to irinotecan. There can be multiple Almac IDs/probesets associated with a given gene. Almac SEQ ID Gene Probe ID Probe Sequence NO ANP32B ADXCRIH.2787.C1_s_at ACATTCCGCCTTCCTTCCATGTAGTCCCTCTTGGTAATCTACCACCAAGCTTGTGGACTTCAC SEQ ID TCCAACAAAATTGTAAGCGTTGTTAGGTTTTTGTGTAAGATTCTTGCTGTAGCGTGGATAGCT NO: GTGATTGGTGAGTCAACCGTCTGTGGCTACCAGTTACACTGAGATTGTAACAGCATTTTTACT 1143 TTCT ANP32E ADXCRAG_AL832674_s_at CTGTGCAATCAAAATTAGAGTACTTTGGTTTGAAAACAACACTTAGAGCCTCCAGATAACTTT SEQ ID TAAGACTTATTTAGCTTTGTGGGTGGTATTTTCATGCAAATAAGTAAGGGTGGGTTTTATATT NO: TTGTAGAAGTTTTCGGTCCTATTTTAATGCTCTTTGTATGGCAGTATGTATATATTGTGTTAA 896 GTTCCTCAAGAATCTCCTTAAAAACTTTGAAGTTAATACTTTTGTGCAACTGTGTTTTGAATA AAGCCATGACAGTGTTAAAA ANP32E ADXCRAG_AY057381_s_at TAATGTTTCTGGGTGTGCAATAGAGTGATCACATCTTTGTTTCTTCATGTACGATAGCTATCC SEQ ID CTACAGAAGATAATGTGTAACTTTTTATAGGAAAAGTGTGGTTTTACTATTTTTGCCTTATCA NO: TTCCAAATAAGAACTAGTCTGTTAATGATCATATTGTATGTAGAGAAAAATTTTCATTGACTC 902 CCATTGTGGAATTCCCTAGCAATTTATTTAGACTTAATTTTTTAAATTCAAGCTTACTGTATT AGT ANP32E ADXCRPD.6256.C1_at AATGTTTTAAGACGGCTCCCTCCAGTTACCCGGTAGGAAGACTTTCTGGCCGAAAATTCTTTG SEQ ID AAAAAATACTTGGAAAAAGGTCCCTCTCGCCCCCCGCTTTTAAACTGGTGGGAGGAGTCCCCC NO: AAACCCCCTGGTGAAACGATCCTCTAGCCATTAAAACGTTCATTTCTTCTGAAAACTTCACCT 1732 GGCCGGCCCATTATTTGCCAATAACCTCTTAAGAGTGGTGAATCTTTTGGGCACCCAGGGAGC GGGGAATAAATTGTGAAGGACCGCCTCGCGG ANP32E ADXCRAD_CN391960_at AAAATTTGCAGTACTCCTGATTATTCTTTTATTGTTTTTGACTGTTCCCTGTTTTTTTCTGTG SEQ ID ACTGCTGTAACTTAAAGTTTTTG NO: 2691 ANP32E ADXCRAD_AI697657_s_at GCAATTCCTTTATGATCACCTTCCCTTCTTGTTTCACTCCCTCCCGCTCTCTCAAAAGGAACT SEQ ID TGGGAAACTTGTGAAACCCAGGAAAACCTTTAGTCTTATACCTCAACTACCTTTCAGTCCTGT NO: CTGGGTTTTAAATAAGTGAAGTAGAAGAAATTGAGTATTTTCTGACATAAGAATATATTATCA 2807 ATACAGTTTTATGCAGTAAGCTCTCCTTACCATANATGTTTCTTGGTTGACAACATCTAAGAC AATATT ARHGAP15 ADXCRPD.9769.C1_at AAAAACATCTTCAGTGCTCCGGTGACAACGTGGATGTCCTCCCACTGGCTGTCGTCCAAATTC SEQ ID AGCTTCTCTTCAGTTTAATGAAGTGACAAATTATTGGCTTGCTCTGGAGGTCAAATGACCACT NO: GTGAAAAATCTGCAGCTTACTAGGGGTGTCCACAGGTCTCCATCCAGTTCTGATAGAAGGGCT 1508 GGTATTCCAGAAACGACTTGGTTGACAATAAATCTTAACTTCTGTATTGTTGCCAGATTGCCA CTAACTCGATATATTCCATCAACATCTAGACCTC ARHGAP15 ADXCRPDRC.9769.C1_s_at TACCCTTCTGCGAGCTGAAAATGAAACAGGAAACATGGCGATCCACATGGTCTACCAGAACCA SEQ ID GATAGCTGAGCTCATGCTGAGTGAGTACAGTAAGATCTTCGGCTCAGAGGAAGACTGACAGAC NO: AAGACAAGCTACTGAATACGTTCACATCTGTCTTGATGCCTAATATTTTTACATTTCTGTAAA 1952 CATATTTCTGAAATATTTTTTGCCTTTCAAGCGACAGATGCCTCATTTTGTGAA ARHGAP15 ADXCRAD_AI510829_at GATAAATCTCACACACATACTTCCACTCATACCCACCACATGTATTATATTAGCAATATCATA SEQ ID CTCTAGGTCTTCTGGTTTGAGTCAGTATAACATGATAGGCACATTTCTATGGAATTTCATGCA NO: TTATTTTCTTTTAATGCTTATGAGGGTAAGTACCAAAATATCCATTTTTCATTCACAGAGTAG 2854 AATTATTTTTTGACTTTTTTTGTGATCTTTTGACCAACTCTCACATCCAGAAAATGTGCCATT ARHGAP19 ADXCRAD_BE278749_s_at GCCACAGCCTGTGCTAAAGAGCCATGGAGCCCTCCCCTGGCCATGTCTGGGGACAGATAGAAC SEQ ID CTGTTGGGGGAAATATTCCCTCACCCCAGGGTTCTTTCTGCAGAGCAAGGGTTGCCTTTGTCC NO: TATCCCTGAGCTTGCTCAACAAGAGAAACAAGGTTTCTTAAGTGTTTTGGTTAAAGTTTTCAT 2729 TCTTATTTGACTATGTATATGTAATTGTAAAGAAACGATCCTATGCATTGTCTTTCT ARHGEF6 ADXCRAD_BM694731_s_at GATGAGTACATATGCATGTTTCGGGGACTTGGCCCTTCTGATGAGGGGCCCTCGGTACTCTGG SEQ ID ATAACGAAGCTTGTGCAGAGTGGTAACCATGCTTACACACTAAACTATAATATAAAGGAAATG NO: AAGCCATGTTAATCTGAGAGCAGTGTCGCCATAGTTGTGTTGTTTACAATACTCTATAAATGG 956 GTTCCTGTTGCCCTGTAATTAAACTGCTGCCCGTAGAGGCCTTTCAGTTCCTTTTCTGTCCTT CCCCTTCTTAACACAAGCTCAAA ATF3 ADXCRAG_AB066567_s_at AGCCGGCCCGCCTGAGAGACACTAGGGGAAATAGCTTTTGTGGGCAAGCAGGGTGGCCGGTGG SEQ ID TGCTCAGCAGTCTTTCCAGTGGCTGTGTCCCTCCTCCAAATGTGGACAGGCCATGACAGAGTC NO: TTAGCCCAAGTCCCACAGATCCCCAAAAGTTCTGTTGATTGCTTCAGGGGATCAGTGAAAATT 841 AGGGAATTTTGTGTGTTGCTATATACATTTTTTCTGGGGAGATGAGCTTCTCATTGAGATCTG TGACTCAGAATCGACTAAGCCACCATAAGTCTGGATT ATF3 ADXCRAG_AY426987_at CGTGAACAGCGTTTCCAATTAGAATCTGCCTGAAAGGAGGTCCCATTTGCCCACTGAGCATCC SEQ ID TGTGTTCTCATGGTGGCTCTAACTCCAGAAGATTTTAACACAGTCTCATCAAACACTGCTTTC NO: AGGGAGGAATTTACACTGAGGTTAAAAGGACTGTTGAGGACTAATGCTAACAGAAGCTAACAT 909 TTATTGCGTAGGACAATACACTAAACACTTCACATGTATTATCCCA ATF3 ADXCRPD.13867.C1_at TTAGCAAAACCCTCAAACACCAGTGACCCAGGAGGGGACAGGCAGGGGACGATGGCAGAAGCA SEQ ID CTCACTTCCGAGGCAGAGACCTGGCCTGGGTGTTGAAGCATCATTTTGCTCCAGGCTCCGCTC NO: GGGGCGGCCAGGGTCGGGACGGGGTCGGGCGGGCTGTTTGTCTGGCCGGCGGGCGAGCACACG 1712 AGGACTCACGGCCGGCGCGCGGGCTGAAGGGTGCGCTCGGGCGGCGGCGAGAGAAGAGAGCTG TGCAGTGCGCGCCTGGCTGCGATCCCGGGAATT ATF3 ADXCRPD.1294.C1_s_at GTGGTACCCAGGCTTTAGCATTATTGGATGTCAATAGCATTGTTTTTGTCATGTAGCTGTTTT SEQ ID AAGAAATCTGGCCCAGGGTGTTTGCAGCTGTGAGAAGTCACTCACACTGGCCACAAGGACGCT NO: GGCTACTGTCTATTAAAATTCTGATGTTTCTGTGAAATTCTCAGAGTGTTTAATTGTACTCAA 1882 TGGTATCATTACAATTTTCTGTAAGAGAAAATATTACTTATTTATCCTAGTATTCCTAACCTG TCAG ATF3 ADXCRPDRC.13867.C1_s_at TGTACCTCTAGAATCCCAGCAGCAGAGAACCATCAAGGCGGGAGGGCCTGCAGTGATTCAGCA SEQ ID GGCCCTTCCCATTCTGCCCCAGAGTGGGTCTTGGACCAGGGCAAGTGCATCTTTGCCTCAACT NO: CCAGGATTTAGGCCTTAACACACTGGCCATTCTTATGTTCCAGATGGCCCCAGCTGGTGTCCT 2007 GCCCGCCTTTCATCTGGATTCTACAAAAACCAGGATGCCCACCGTTAGGATTCAGGCAGCAGT GTCTGTACC ATF3 ADXCRAD_AB078026_s_at GAATGCTGAACTGAAGGCTCAGATTGAGGAGCTCAAGAACGAGAAGCAGCATTTGATATACAT SEQ ID GCTCAACCTTCATCGGCCCACGTGTATTGTCCGGGCTCAGAATGGGAGGACTCCAGAAGATGA NO: GAGAAACCTCTTTATCCAACAGATAAAAGAAGGAACATTGCAGAGCTAA 2779 BATF ADXCRPD.6100.C1_at CACACAGACTGTGGCAGAACTGCGCCCCATCCCGCAGAGGCCCCCTGTCCACCTGGAGACCCG SEQ ID GAGACAGAGGCCTGGACAAGGAGTGAACACGGGAACTGTCACCACTGGAAAGGCGTGAAGCCT NO: CCCAACAGTGCCGCAGCGTTTCGAGGGGCGTGTGCTGGACCCCACCACTGTGGGTTGCAGGCC 1716 CAATGCAGAAGAGTATTAAGAAAGATGCTCAAGTCCCATGGCACAGAGCAAGGCG BCAT1 ADXCRAG_AL390172_s_at AATTTTCTTTGTGGCAGTCATTTATTAAGGATTCAACTCGTGATACACCAAAAGAAGAGTTGA SEQ ID CTTCAGAGATGTGTTCCATGCTCTCTAGCACAGGAATGAATAAATTTATAACACCTGCTTTAG NO: CCTTTGTTTTCAAAAGCACAAAGGAAAAGTGAAAGGGAAAGAGAAACAAGTGACCGAGAAGTC 890 TTGTTAAGGAATCAGGTT BCAT1 ADXCRPD.1208.C1_at TAAAAACAGTGGGTTGAGCCCCAGCTCCATGTATTAGGTAGCTAGGTATATTGTGGGATTATT SEQ ID CCTTGTTAAGTCACCCCAGGAAACATTTGCAGAATTTAGAAATGCATCCAGATTTGTGAGTTT NO: ATTTTTAAGACCTGACTAAAAATCTGCACTCTTCAAAAACTTATTGATGAAGTACAAATTGAG 1878 GCAGAAATTTACATTCCTTTGCTTAATCCCTGAGAATGAGTATAATGATCATAGAACTAGTTC GAGAGACTGCAATGTGTCCAGACTACTGTCAGACC BCAT1 ADXCRAD_BU953528_at TATTTGCAGATTCCTCATCAAATCTGTAATTATGCACAGTTTTCTGTTATCAATAAAACAAAA SEQ ID GAATCCCAAANNNNNANNNNNNNANAAAAAAAANNAACATGTCCGGCCGCCCTCGGCCCTCGA NO: AGAAACTTTCTAGGAACCTTCGTTTTGGGCGCGCGGGCCCCAGTTAAGGTAGGTGAACATGG 2413 BCAT1 ADXCRAD_BU953528_x_at TATTTGCAGATTCCTCATCAAATCTGTAATTATGCACAGTTTTCTGTTATCAATAAAACAAAA SEQ ID GAATCCCAAANNNNNANNNNNNNANAAAAAAAANNAACATGTCCGGCCGCCCTCGGCCCTCGA NO: AGAAACTTTCTAGGAACCTTCGTTTTGGGCGCGCGGGCCCCAGTTAAGGTAGGTGAACATGGG 2414 GCCATAGCTGGTTTCCCTAGGGAGAACCCTGGGCCATGAACTA BCAT1 ADXCRAD_BG393815_at CTCAAAAGATTGTCGTAAGAACAACAATGTCAAGACCAAAAAA SEQ ID NO: 2431 BCAT1 ADXCRAD_BM472661_at TTCCTCCATGATTTTAGTGGCCTCCTTTTGTACTTCACTCAGATACTAAATAGTAGGTTATTC SEQ ID CTTTATATAAGGTACATTTCTGCTCC NO: 2671 BCAT1 ADXCRAD_BM472661_x_at GAGTGATTGTTTCTTCATGCCAGAGAANATGAATTGCAATCATCAAATGGTGTTTCATAACTT SEQ ID GGTAGTAGTAACTTACCTTACCTTACCTAGAAAAATATTAATGTAAGCCATATAACATGGGAT NO: TTTCCTCCATGATTTTAGTGGCCTCCTTTTGTACTTCACTCAGATACTAAATAGTAGGTTATT 2672 CCTTTATATAAGGTACATTTCTGCTCCTCAAACAAAT BIRC3 ADXCRPD.2751.C1_at GTGTTATATGAGCATGATTTGGTAACTTCAGG SEQ ID NO: 1557 BIRC3 ADXCRPD.2751.C1_s_at TTAATCCGGAAGAATAGAATGGCACTTTTTCAACATTTGACTTGTGTAATTCCAATCCTGGAT SEQ ID AGTCTACTAACTGCCGGAATTATTAATGAACAAGAACATGATGTTATTAAACAGAAGACACAG NO: ACGTCTTTACAAGCAAGAGAACTGATTGATACGATTTTAGTAAAAGGAAATATTGCAGCCACT 1558 GTATTCAGAAACTCTCTGCAAGAAGCTGAAGCTGTGTTATATGAGCA BIRC3 ADXCRPD.793.C1_at TGACACATTAAAATACTTCTACAGTGACAAAGAAAAATCAAGAACAAAGCTTTTTGATATGTG SEQ ID CAACAAATTTAGAGGAAGTAAAAAGATAAATGTGATGATTGGTCAAGAAATTATCCAGTTATT NO: TACAAGGCCACTGATATT 1608 BIRC3 ADXCRPD.793.C1_x_at TGACACATTAAAATACTTCTACAGTGACAAAGAAAAATCAAGAACAAAGCTTTTTGATATGTG SEQ ID CAACAAATTTAGAGGAAGTAAAAAGATAAATGTGATGATTGGTCAAGAAATTATCCAGTTATT NO: TACAAGGCCACTGATATTTTAAACGTCCCA 1609 BIRC3 ADXCRPD.1900.C1_at ATGAACATTTAGGGACTGTGGTTTTTATAAAGAATTCGGGGAGAAAAATTTATAAGGCCACGA SEQ ID CCCGGGNTTAACAGAAAAGGNAAAAAACTGGTTGGCGCCTTCGGGCCTCAAGAGGTT NO: 2273 BIRC3 ADXCRPD.1900.C1_x_at GGGACCATTTCTCTGTCTTTTTTGATCAGGGCCTATACATCGAAGGTGTGCATATATGNTGAA SEQ ID TGAACATTTAGGGACTGTGGTTTTTATAAAGAATTCGGGGAGAAAAATTTATAAGGCCACGAC NO: CCGGGNTTAACAGAAAAGGNAAAAAACTGGTTGGCGCCTTCGGGCCTCAAGAGGTT 2274 BIRC3 ADXCRPD.1900.C2_s_at TCCTTCCCATAAGATGCTTCTTCATTGCCACTTGTAGAACACGGGGGTCAACCCATCATAAAA SEQ ID TCTATTATGGAATGCCTGAGACAAGAATCAAACAGTCCCTTTAGTAAGTTTGTTTATTCACTT NO: CTCTATTGATTCATTCAAGAAGTCTCATGCCAGCCCCACCTATTGGAAGAAGGTCTGAGTTTT 2275 ATTCTTATCTCTTTGGTATTAATTCTGAAACTTAGAAAGTACACTGGTTAGCAATGCTTGGGA CCAACAG BIRC3 ADXCRAD_U37546_x_at TATTTTGGCATTGTACTAATACCTGGTTTTTTTTTTGTTTTGTTTTTTTGTACAGACAGGGCA SEQ ID GCATACTGAGACCCTGCCTTTAAAAACAAACAGAACAAAAACAAAACACCAGGGACACATTTC NO: TCTGTCTTTTTTGATCAGTGTCCTATACATCGAAGGTGTGCATATATGTTGAATGACATTTTA 2814 GGGACATGGTGTTTT BIRC3 ADXCRAD_AA805622_at GTGCCTACTATTTAAATACCCTATACCTGAGTTACAAATCACCTAAGCACAATTACAAATAAT SEQ ID TCAGCCTAGCACCCATGCAGGACACTGGCTAGTACATGGGTAGCCAGCAGAGCCTCTTAGCAG NO: AGGCAAAATCAATTGCATTTCAAGGAAATAAGTCTCCCAGCATCAGAATGCAGAGATGGATTC 2860 TTTCCTCCCCTCACTTGGTCCCTAATTGTTCTCTT C1orf114 ADXCRAG_BC026073_s_at GTAGAGTAAGTAAAACTTCTCTGAAAAATAAGTTCATACAGATATGAAAGCTGAACTTATTTA SEQ ID TAGAAGGGAGTCTGGATATCAGACTAACAGCCTATGGAAGAAGTAGAAAAGTTGTTCAAGAAC NO: TACCCTTGCAAAAGATGCAACATGCAGATAACTACAATTAGGTTCTAAGAGGTCTTGTGAAAA 951 TAAAATGATTCCTATTTTGTTCAGACTTTGATGGAACAG CBFB ADXCRIH.116.C1_at TTTGTAAGGAGGTGCCAAATGACTTAGCACTGTTTTCCACTCTGTATCTNNNNNNNNNGTTGC SEQ ID AATTTGACAGTAAGCCTATTTAAAAAATATTCTTACATTAATTCATCTCAAAAGGTTCTATTA NO: ATAGTCCTTTTGCAAAATACCATATATATAACTGTGAACGTTTTTTCCAGAATTAATGGAAGA 1283 AAATGCATCCTCTGCACAGATGAACATTTTCTCT CBFB ADXCRIH.116.C1_x_at GAGGTGCCAAATGACTTAGCACTGTTTTCCACTCTGTATCTNNNNNNNNNGTTGCAATTTGAC SEQ ID AGTAAGCCTATTTAAAAAATATTCTTACATTAATTCATCTCAAAAGGTTCTATTAATAGTCCT NO: TTTGCAAAATACCATATATATAACTGTGAACGTTTTTTCCAGAATTAATGGAAGAAAATGCAT 1284 CCTCTGCACAGATGAACATTTTCTCTCTAAAACCCTCGTG CBFB ADXCRAD_AL557216_s_at ATTTTTCTGTCATTTAGCACCATGCTGCTTCTGTCTGTCTTAATGCTGGCATTAAGATCATGA SEQ ID GCCCTTTTTCTCCAGTAGTACAGGCTTTGAAAACTACTTCTATTAAGTTATTGATGCAATTTG NO: ATATTTTTTCATAATCTATATTTAAACAAAATTACATCATTGCATCATCTTTTCTAAATTCAT 1332 CTCCATTAAAACTTGCCTTAAGCTACCAGATTGCTTTTGCCACCATTGGCCATACTGTGTGTT T CBFB ADXCRAD_AL561208_at TCTCAACCTTAGGCAGTAATAGACATCACAAACTGCCATGGTTTTGCACTATGATTATAATAC SEQ ID CTGCATTTCTAATTTTTTAAGCATGTAGCCAGTAATAATTTGAAGTTTTTTTTCTATGCAAGC NO: TTACCTTGTTGGCATTATTTTTAGGGAGTTGAA 2455 CBFB ADXCRAD_AL561208_x_at CTCAACCTTAGGCAGTAATAGACATCACAAACTGCCATGGTTTTGCACTATGATTATAATACC SEQ ID TGCATTTCTAATTTTTTAAGCATGTAGCCAGTAATAATTTGAAGTTTTTTTTCTATGCAAGCT NO: TACCTTGTTGGCATTATTTTTAGGGAGTTGAA 2456 CCDC109B ADXCRAD_BM830891_at GAGTAGGCAATTTCTTCAGTTCTTCCACAAGAAATCAAAGCAACAGCACTTTGATGTGCAGCA SEQ ID ATACAACAAGTTAAAAGAAGACCTTGCTAAGGCTAAAGAATCCCTGAAACAGGCGCGTCATTC NO: TCTCTGTTTGCAAATGCAAGTAGAAGAACTCAATGAAAAGAATTAATCTTACAGTTTTAAATG 2712 TCGTCAGATTTTCCATTATGTATTGATTTTGCAACTTAGGATGTTTTTGAGTCCCATGGTTCA TTTTGATTGT CD247 ADXCRAD_NM_198053_at AGAGGAGGCCGTTGATTCACTTCACGCTTTCAGCGAATGACAAAATCATCTTTGTGAAGGCCT SEQ ID CGCAGGAAGACCCAACACATGGGACCTATAACTGCCCAGCGGACAGTGGCAGGACAGGAAAAA NO: CCCGTCAATGTACTAGGATACTGCTGCGTCATTACAGGGCACAGGCCATGGATGGAAAACGCT 2773 CTCTGCTCTGCTTTTTTTCTACTGTTTTAATTTATACTGGCATGCTAAAGCCTTCCTATTTTG CATAA CD3D ADXCRAG_BC039035_at AAAAATAGATGTTGGGTCTCGTCAAGTGCTTACCCTGCATCCATTGAGATGATAATATGGTTT SEQ ID TACTTTTTTAGTCTGTTAATATGGTACATTACATTGATGGCACGATATGTTAAACCAACCT NO: 959 CD3D ADXCRAG_BC039035_x_at AGTTCTTTTCTTTCTAGTTTGCTGAGAATTTTTATCAAAAATAGATGTTGGGTCTCGTCAAGT SEQ ID GCTTACCCTGCATCCATTGAGATGATAATATGGTTTTACTTTTTTAGTCTGTTAATATGGTAC NO: ATTACATTGATGGCACGATATGTTAAACCAACCTTTCATTCCTGAAAAAAACTCTAGTCATTT 960 GGTATTATTCT CD3D ADXCRAD_BX457462_s_at CGTGGCTGGCATCATTGTCACTGATGTCATTGCCACTCTGCTCCTTGCTTTGGGAGTCTTCTG SEQ ID CTTTGCTGGACATGAGACTGGAAGGCTGTCTGGGGCTGCCGACACACAAGCTCTGTTGAGGAA NO: TGACCAGGTCTATCAGCCCCTCCGAGATCGAGATGATGCTCAGTACAGCCACCTTGGAGGAAA 2553 CTGGGCTCGGAACAAGTGAACCTGAGACTGGTGGCTTCTAGAAGCAGCCATTACCAACTGTAC CTTCCCTTCTTGCTCAGCCAATAAAT CD53 ADXCRPD.1819.C1_at GGTTGCTATGCGAAAGCAAGACTGTGGGTTCATTCCATTTTCCTNATATCGNGATCATCACCA SEQ ID TCTGTGTATGTGTGAATGAAGGTTTTGGGGATGTCCTTTTGCCCTGACCCTGAACTGNCAGAT NO: TGACAAACCCAGCAGACCCATAGGGTATTGATCTGCAGNAANTCCTTGGGGTGGAAAGAAACT 1497 GGTTTCATCTTCGGGAATGCCAAACCATTTTATAGCATGGAGCCCCTACCTGT CD53 ADXCRPD.3701.C1_at TGGACCATTGTCACAACCCTCTGTTTCTCTTTGACTAAGTGCCCTGGCTACAGGAATTACACA SEQ ID GTTCTCTTTCTCCAAAGGGCAAGATCTCATTTCAATTTCTTTATTAGAGGGCCTTATTGATGT NO: GTTCTAAGTCTTTCCAGAAAAAAACTATCCAGTGATTTATATCCTGATTTCAACCAGTCACTT 1629 AGCTGATAATCACAGTAA CD53 ADXCRAD_AW293276_at TTGAACACTCAGTGCTGACCAGAGATTAACATAGGGCATGCAATACTAAAATTGGTTTGCATT SEQ ID TCACTTTCTGCTTCAACGTTCAGTAAATCCATCATAGCCCTACCAAGTGCCAGGGCAGTTGCT NO: GGTCAGTGGTTGTCCTAGTCTTTCTCCACAAACCTGAAAAACCCTGGAGATTTCCAAACCCCT 2849 TCAGGAGCAGATAACATGAGGAGACAAGACCTCAGGGATTCAGTCTAGTTGGAAGATAGTTGT GGCTTCTTCTCAGAGCCTATTCTGGAGGTCCAAAT CD93 ADXCRAG_NM_012072_at TATGTGCCTATCCTAATAAACTCTTAAACACATT SEQ ID NO: 1039 CD93 ADXCRAG_NM_012072_s_at CAAATTTGTTTGACTAATTCTGGAATTACAAGATTTCTATGCAGGATTTACCTTCATCCTGTG SEQ ID CATGTTTCCCAAACTGTGAGGAGGGAAGGCTCAGAGATCGAGCTTCTCCTCTGAGTTCTAACA NO: AAATGGTGCTTTGAGGGTCAGCCTTTAGGAAGGTGCAGCTTTGTTGTCCTTTGAGCTTT 1040 CD93 ADXCRPD.8173.C1_s_at GCAGGTATTTTCTACGGGTGTTTGATGTTCCTGAAGTGGAAGCTGTGTGTTGGCGTGCCACGG SEQ ID TGGGGATTTCGTGACTCTATAATGATTGTTACTCCCCCTCCCTTTTCAAATTCCAATGTGACC NO: AATTCCGGATCAGGGTGTGAGGAGGCTGGGGCTAAGGGGCTCCCCTGAATATCTTCTCTGCTC 1812 ACTTCCACCATCTAAGAGGAAAAGGTGAGTTGCTCATGCTGATTAGGATTGAA CD93 ADXCRAD_BU150433_at ATTTCCATCACCTTTGAAACATAGCTTTTAGCTTGGGAAATCTGA SEQ ID NO: 2743 CD93 ADXCRAD_BU150433_x_at GATCATTAGGTACTTTTGTTTCAACCTTTATTCCTGTAAATATTTCTGTGAAAACTAGGAGAA SEQ ID CAGAGATGAGATTTGACAAAAAAAAATTGAATTAAAAATAACACAGTCTTTTTAAAACTAACA NO: TAGGAAAAGCCTTTCCTATTATTNTCTCTTCTTAAGCTTCTCCATTGTCTAAATCAGGAAAAA 2744 CAGGAAAACACAGCTTTTCTAGCAGCTGCAAAAATGGTTTAATGCCCCCCTACATATTTCCAT CACCTTTGAAACATAGCTTTTAGCTTGGGAAATCTGA CD99 ADXCRIH.3577.C1_at GTTGGCATTCCGGTGGCTCTCCATGTCCACCTCCCCTTGTTCTGCATTTTCTTTGAAGCATAG SEQ ID CTTCTTTTTCTGGTAAGCAATGAAGCTAGAGATGGCTCCAGCCACGGCGACCACGACAGCCCC NO: CACAATCCCGGGGATCACGCCTGGGGCGTCGGCCTCTTCCCCTTCTTTCCTGTGGCTGCCTCC 1223 ACCATCACTGCCTCCTTTTCCTTCTCCACCTGAAACGCCATCCGCAAGGTCAGCATCTGAAAA GCTACCGGAGGAACTAG CD99 ADXCRIH.3577.C1_x_at TTGGCATTCCGGTGGCTCTCCATGTCCACCTCCCCTTGTTCTGCATTTTCTTTGAAGCATAGC SEQ ID TTCTTTTTCTGGTAAGCAATGAAGCTAGAGATGGCTCCAGCCACGGCGACCACGACAGCCCCC NO: ACAATCCCGGGGATCACGCCTGGGGCGTCGGCCTCTTCCCCTTCTTTCCTGTGGCTGCCTCCA 1224 CCATCACTGCCTCCTTTTCCTTCTCCACCTGAAACGCCATCCGCAAGGTCAGCATCTGAAAAG CTACCGGAGGAAC CSDA ADXCRIH.625.C1_s_at GTTCATTTTGGATGCTGGTGCTAAACCTCCAAGTGTCATGATTTNNNNNNNNNNNNNNTTTAT SEQ ID GTCCTTCTTATTTATTTCTAGGATGAGGGGAGGAAAACATTTTTGCTTTCTTATGTGACTCTC NO: TTTGAAAATGTGC 1107 CSDA ADXCRSS.Hs#S1919678_at TGCTGCACCGCCTACAAAATCAAATAAAGTTGATTATCCAACAGACAAAGGGAAGGCACACAC SEQ ID AACTCCTTTAGTTTATACTACTGTTTCTGATTACTAAACAGGTTCTGAAACTGTTTCTGATTA NO: CTAAAACCAGGCTTAGTTAGGGACTTTTAGCATCAGTATTCCTAAGTGGTCACTAGTAGTTAA 2096 AACACTGCCTGTCTAGAAAAAAGAAGTTGAGTATCATCCACTCTGTCTGAATGCTTATACCCT CAACAAAGCTTATCAAAATGAGGTCAATCCCAGAAATA CTCF ADXCRAG_BC014267_s_at AATCATGTAGCAGAATGGCACCCAGACCACTGCCCACCAGTGACGGACATGCACGTGGCAGAT SEQ ID CATGATTTCCAGCCCACGGAGCCAGCATTTGAACCTTGTATAATTAACTTTCAGTTATGATTT NO: CCCATCGACATTTTCTTTGCCCTGTTTGTAGCTGATTGTTGTGTTTTATAAATCTTCTGTTAA 939 GGCAGAAGGGTGATTATGAGTGGTTCACAGCAGCCCTTATAAGCTGGGCCAGAAAATTTCACT AGGTCAG CTCF ADXCRPD.12254.C1_at GAGGGCATAGCGCTCATGAAACACAGCATCACAGTAACGGCATTTCTTGCCTTGCCCAATATA SEQ ID GGAATGCTGCTTTCGCAAGTGGACACCCAAATCACTTTTTCGGGCTATGACTGTGTCACAGTG NO: GGGACAGTGAAGTTTGGCCGCATTTTCTGTGTGCTTCTGTAAAATGTGCATCTTCATGGTACC 1545 ACTTTGGGTAAACCGAGCATGACAAATATAACATTCATAAGGCTTTTCCCCTGAATGGGTTCT CATGTGCCTTTTCAGCTTGTATGTGTCCCCGCTGGACTACAGCA CTCF ADXCRPDRC.12254.C1_s_at GTCACACAAGAATGAGAAGCGCTTTAAGTGTGACCAGTGTGATTACGCTTGTAGACAGGAGAG SEQ ID GCACATGATCATGCACAAGCGCACCCACACCGGGGAGAAGCCTTACGCCTGCAGCCACTGCGA NO: TAAGACCTTCCGCCAGAAGCAGCTTCTCGACATGCACTTCAAGCGCTATCACGACCCCAACTT 1961 CGTCCCTGCGGCTTTTGTCTGTTCTAAGTGTG CTCF ADXCRAD_CB164277_at TAAAAAGTGATTCTTGCACATGAACTGTCACATGTTTAAAAATGTGTTTTTTAGAGAGCCTCA SEQ ID GTCTTACTGATTTCAAACACTTTTTTCTTCTGTGTATTGCTTTTAAGAGAGCCATCAGTTAGC NO: TATCAGACTCTAGGTTGATGCATTTTGTACTTAGCTGTACTGTGTGATATTTTTCATTATTTT 2395 AGGACGCCAACATGAGACCTGTAATAAAATATGTAATGGGGTTGAAAGCTGGGGAGGAGGATC TACTGCTGTACAGCTAATAAATCATAACGGAT CUTC ADXCRPD.14073.C1_at TTCTACTGGCTTCACATTAACAATAATTTTNGTTGAATTTGAATTCTTAAAAATCTACTGACA SEQ ID ACATTTAAGTC NO: 1642 CUTC ADXCRPD.14073.C1_s_at TCCTGAAGTACATGCCATGTACTCCCCCTTTATTTCTACCTTGGATCAATGGCCTCTGCGGAG SEQ ID TGTAGTGAAAGACATCTTTTTATTATGATCTACACTTTAAAAAACCAAAGGCTGCCTGTATTA NO: CA 1643 CUTC ADXCRPD.14073.C1_x_at CTCAATCCAAAATTACCCTTAAGTGGAAGTCCTGAAGTACATGCCATGTACTCCCCCTTTATT SEQ ID TCTACCTTGGATCAATGGCCTCTGCGGAGTGTAGTGAAAGACATCTTTTTATTATGATCTACA NO: CTTTAAAAAACCAAAGGCTGCCTGTATTACATTTGCTTTGGGGAGTTGTTAAGACTCTGTTTT 1644 TTCTACTGGCTTCACATTAACAATAATTTTNGTTGAATTTGAATTCTTAAAAATCTACTGACA ACATTTAAGTCAGTGTGAGGAA CUTC ADXCRPDRC.2453.C1_at ACAGATGTGACCAAAGTAAGGACTTTGAATGCTATCGCAAAGAACATCCTGGTGTAGCCAGAC SEQ ID CTCTCTGAGAGACATGGATATCACAGGGATGAAGGTAGAACTATAATCTGCAATTCTCTATGA NO: CACAGCTTTAACCTTCTTCTCTGGCCAGGACAGTCGCAATCCTTTGNTTTTAATTTTCACATG 1945 GGCCATGGGAGAATGTGGCCCAAAGAAAGAAAAAGAAATTTGGAAACAGGAGATACAGGTCAC TTTCCTTTTTGCTTAGTCCTTAACCAGTG CUTC ADXCRPDRC.2453.C1_s_at TGCTATCGCAAAGAACATCCTGGTGTAGCCAGACCTCTCTGAGAGACATGGATATCACAGGGA SEQ ID TGAAGGTAGAACTATAATCTGCAATTCTCTATGACACAGCTTTAACCTTCTTCTCTG NO: 1946 CXorf57 ADXCRAD_NM_018015_s_at ATCTGATTCCAGTTAAGCTATAAACTTGTGGGATTTTCTTGTAGCCCTATAGTTCTGTGACTT SEQ ID CATTTGCTATACGCTTTAAATGTGTTGAGCAGCCTATGAACCTAAAGACATACTGCAGTTTGT NO: TCATAAATGTATTCAGTCTTTTATTCTTTATAATTGTGTGTAAATGTTAACTAAACAGTGGAT 2774 TCCTCTCGTGTTACAGTTTTGAGTGAA CYFIP2 ADXCRAG_AF132197_s_at TGGGAATTTTTGTACAATGAATTTACATTTATTTATGGTGACATATTTACGCTTGTGATCAAA SEQ ID TAATGATGTTAAATTCTTAAATCATATTTGCTATGCAGCTGAAGATGATATTTTGA NO: 863 CYFIP2 ADXCRAG_AF132197_x_at TTTCAGAAACTGTCAAATGTACCATATTTGTATTAAGAGTTGTTGGGAATTTTTGTACAATGA SEQ ID ATTTACATTTATTTATGGTGACATATTTACGCTTGTGATCAAATAATGATGTTAAATTCTTAA NO: ATCATATTTGCTATGCAGCTGAAGATGATATTTTGATTTGTATTTTGGGGGTACCTGTGTTGA 864 GTTGATAAACATTTCCATCTTCATTAAAACTGCTTCCAAACTAAA CYFIP2 ADXCRAG_BC011762_s_at AGACAGACAGTTCCACTGTGGAGCATGTGCGCTGCTTCCAGCCACCCATCCACCAGTCCTTGG SEQ ID CCACCACTTGCTAAGCAGAAGATCCTGCAGACCCTTATCTGGAGGAGGAAGAGAAGCAGGAGA NO: GAGAAAGCCACAGCCAGCCTGCCATAGGATCCAACTGGACAACGTGTGGGATGGACCTGGAAA 932 CAAGCACCTCCCCAAACACATCACCACTCCCTAGGGCGGGGCCTGTGCATGCTCTCCCATGAC ATCTCCATGCTGGTTTCTCCATAGCATAAATG CYFIP2 ADXCRPD.9810.C1_s_at CCATGCCGAGCGCAGGAAGGACTTTGTCTCTGAGGCCTACCTCCTGACCCTTGGCAAGTTCAT SEQ ID CAACATGTTTGCTGTCCTGGATGAGCTAAAGAACATGAAGTGCAGCGTCAAGAATGACCACTC NO: TGCCTACAAGAGGGCAGCACAGTT 1540 CYFIP2 ADXCRSS.Hs#S2524484_at GGCTCAGTGCGCACAACTAGCTAGAGGCACTGACTTTGTAAGCAACAACACTATCTTCTTGAG SEQ ID GTCTAATAATTGCCTTGGCAAAGGGCAGCCAATGCCAACGAGGAACCCTGTGTACACAAGTTT NO: CTCATCCCGAAAGTGGACACTGGGTGCTCAAAAAATGCCTTCTGGTGACAGTAACACCTGACC 2071 AGTCAAACAAACATGCACGCA CYFIP2 ADXCRSS.Hs#S3733207_at GCCTATGTTGTAGAATCCCTCGTACCCAGAGTGGGAGAAGATTACACCCGGGGCACTGCAGGG SEQ ID AGGGAACCAGGAGAGATGAAGTAGTAAGCTGAGGCATGCCCTTCTGGCCAGGCTGGCGTCTCT NO: GGGCATGGCCACATCTGTTCACAGTCTGAGACTTGAGTCCTGGGGTCACACAAGGGCACTGGG 2161 TAGGAGATGTCTATCTTGGGAGGAGGTCTTGGGAAGCAACCACAGATAG CYFIP2 ADXCRAD_AV725374_at GATATTTTGAATTGTATCTTGCGGGTCCCTGTGTTGAAGTGATAAACATTTGCATCTTATTAA SEQ ID AACTGCTTTCACACTTGTAGACCCCACAACTTACAACAATTAATTGGCCGTTGTTTTACAACG NO: GCTGACTGGGAAACCCTTGCCGTCCCCAACTTTATTGCTTGT 2591 DDX23 ADXCRIH.3762.C1_at TGAGGAAGGTGATGGCCACCCCACTCTTGCCTGCTCGTCCCGTGCGGCCAATGCGGTGGATGT SEQ ID AATCTTCAATATTTTTGGCCATATCATAGTTGACAACCATAGACACATCTTGGATGTCAATAC NO: CACGACCAGCCACATCTGTAGCCACCAAAATATCCTTGGCCCCAGCCTTGAGGTTGGACAACG 1145 CAAACTCTCGCTGCTCCTGGCCTTTTCCACCGTGCAGTGTGCAAGCATTGTACCCCATCTTCT CCAGGGATTTGGCCAACACGTCGCAGC DDX23 ADXCRPD.1564.C1_s_at TGGCACCATGAGGATTACAGACAGTGGAATCTTACTGTCATCTGGACAGCTGTTTTCCTGTTT SEQ ID GGATGGTAAAGGAAGTTGAGAGTCTTTAGACCTGTGCACAGCCCCACACCAAGGGGTGCTGTA NO: TGCTCTAGGCATCCCCTCCCCCAGGGGATTTTCTAAGTAGATGGGGGGACACGGTGAACTGGC 1441 TGTGTCCATCTTTGTCACTGAGTGAAATCTCTGTTTTCTATTCTCTGAGAAGATAAGTTTGTA TGTTCTGAGAATA DDX23 ADXCRPD.15034.C1_s_at GAAGGACCGAGATCGAGACAAGGATGGGCACAGACGGGACAAGGACCGTAAACGATCCAGCTT SEQ ID ATCTCCTGGTCGAGGAAAAGACTTTAAATCTCGGAAGGACAGAGACTCTAAGAAGGATGAAGA NO: GGATGAACATGGTGATAAGAAGCCTAAGGCCCAGCCATTATCCCTGGAGGAGCTTCTGGCCAA 1698 GAAAAAGGCTGAGGAAGAAGCTGAGGCTAAGCCCAAGTTCCTCTCTAAAGCAGAACGAGAGGC TGAAGCTCTAAAGCGACGGCAGCAG DOCK2 ADXCRAD_NM_004946_at GTAGATTCCTGAACTCAAGGTACCAGCAAGAATGCCTTCTCCCAGTGTGCTCTCCCCAACATC SEQ ID CTAGGCACAGCTTTCATAACCCAGTTTCTTAGGTGTAAGAAACTGCTTTTATCTCATTTATTA NO: AGTCTCAGAACTTAACAGAAAAGGAAGCCTTTTAAATATTCTTTTTAATTTTATTTTAGATTA 2777 ACAGTTTTGTACTTTACATTTTTTTATACAACCAACCAGTTTCTTTTCTAGCCAATCATCTCT GAAGAGTTGCTGTTTCTTACTGACAAT DPY19L 1 RDCR162_A06_s_at AGATGTAGTTCTCCGTAGGCAGCAGGTCATGTAGCAGTCATTCTTTTACAACTTCTAGGACTT SEQ ID TGTAAACACTGTTCTGGAATACAGTGGTGAAGTGAGGTTTGGAATTCTTCACTAAGAGGTTAC NO: ATAAGGGAGTTTTCCCAGCATTGGCAGGATCTTCTACATCTCAAATTTCAGCATACTGCAACC 1358 AGGCTTGGATCTTCTTACACACCATGACTCTTCTAGAATGTAATAGTTCACTTTTAACTTTAT CAGTTCTCGCTTCACTTCTTCGGCTGCTTTCCGACTATACATTGA DPY19L1 ADXCRPD.17046.C1_at AAAAATGACTTACACCTTTATCAATTGGTTACTATTTCAATGCACCCTTTAA SEQ ID NO: 1786 DPY19L1 ADXCRPD.17046.C1_s_at TGGTGAAGGATTCCAAACCTCACTTCACCACTGTATTCCAGAACAGTGTTTACAAAGTCCTAG SEQ ID AAGTTGTAAAAGAATGACTGCTACATGACCTGCTGCCTACGGAGAACTACATCTGTAATGGTT NO: TTAATGTTTTGCTAAGTCATGTGTTGTTCATATCCCAAAAACTTTTATAGGTAACTGTTTTCA 1787 AATAGA DPY19L1 ADXCRPD.10268.C1_s_at TTTTTGCTTTAGTATGAGGAAAGTAAGGATGGGCAAAGAAGCGATCAAAATAGCTATTGCTAC SEQ ID AACATTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTAAAAATGCTT NO: GGCAAAAAAAATATAGTGTTAAAATAGGCCAGTGATATTAATGAGAAAATGAAAGTATGTATC 1880 AGGAATAAAGTGATATTGCATAGGAGTATTGTATTTTTATGAAT DPY19L1 ADXCRAD_BU607292_at TATTGCTACAACATTTTCGAAAACAAAGTTGGGGCTGTATTTCTTTAAAAAGATAAGCCTCTA SEQ ID AAAATGCTTGGCAAAAAAAATATAGTGTTAAAATAGGCCAGTGATATTAATGAGAAAATGAAA NO: GTATGTATCAGGAATAAAGTGATATTGCATAGGAGTATTGTATTTTTATGAATTTTATGCCAG 2540 TTGTTTACATGTACCCTCGTTCCGAA DPY19L1 ADXCRAD_BU607292_x_at GTTTTGCATATTGTTAGCATTTACAAATATTTTTGCTTTAGTATGAGGAAAGTAAGGATGGGC SEQ ID AAAGAAGTGATCAAAATAGCTATTGCTACAACATTTTCGAAAACAAAGTTGGGGCTGTATTTC NO: TTTAAAAAGATAAGCCTCTAAAAATGCTTGGCAAAAAAAATATAGTGTTAAAATAGGCCAGTG 2541 ATATTAATGAGAAAATGAAAGTATGTATCAGGAATAAAGTGATATTGCATAGGAGTATTGTAT TTTTATGAATTTTATGCCAGTTGTTTACATGTACCCTCGTTCCGAA DPY19L1 ADXCRAD_BF447983_at GAATAAGGCCTCTGCTAGAGTCCCAAATAAAGGATTAATTATCCTAAAGAAAAAGCCCCAAAA SEQ ID TAATAATCTTTGGGATCAAAAGGATTCTACCATCAGCCTCATATAAGTGGAACACAATGTAGG NO: AAGCTCTTTTCTCAACCTGCTTTCACTACTCCCAGATTCAAGTAAAGCCACAACCAATTTACA 2870 AGGCCCAGTACA EIF1 ADXCRAD_BP342358_s_at GGAGCTTTTGGTGGTAGATCCCCTGGTGTCTCCAACCTGACTAGGTGGACAGAGCTCAAAGAG SEQ ID GCCCTCTTACCGCTAGCGAGGTGATAGGACATCTGGCTTGCCACAAAGGTCTGTTCGACCAGA NO: CATAT 1279 EIF1 ADXCRAD_CX761856_s_at GTTTGCCTGCAATGGTACTGTAATTGAGCATCCGGAATATGGAGAAGTAATTCAGCTACAGGG SEQ ID TGACCAACGCAAGAACATATGCCAGTTCCTCGTAGAGATTGGACTGGCTAAGGACGATCAGCT NO: GAAGGTTCATGGGTTTTAAGTGCTTGTGGCTCACTGAAGCTTAAGTGAGGATTTCCTTGCAAT 2529 GAGTAGAATTTCCCTTCTCT EIF4A1 ADXCRIH.1587.C1_s_at GAGGACTCTTCGAGACATTGAGACCTTCTACAACACCTCCATTGAGGAAATGCCCCTCAATGT SEQ ID TGCTGACCTCATCTGA NO: 1208 EIF4A1 ADXCRPD.16013.C1_s_at CTTGGCTCTCAGTTTTCTCAGAGTGAACATGCCTCGTAGCTTGGGTCCTATGGCAGGAGTGCA SEQ ID ATAGGACATGGATATGCATCACCTGTTCTATAAAACTGGTTGCTGGCTG NO: 1748 FAM129A ADXCRAG_AB050477_s_at GTGCAAAGGGCTTAGCTAAGTTATCGAGCTTAAAACCCGTCAATTAAACAAACATTATTTGAA SEQ ID CAGTTACTGCATGCCACGCACTGTGTTGGGCTTAGTAATAAAAAAAAGAAAAGATAAGTGCTT NO: GTTCTAGCATAAATTAAAAGGTCCAAGGGAATTTAATCTGGAAGAGAACATATGCCAATTTTT 838 AAACTATGACAGCTTTTTTTTTTCTCTTTCCATTCAAATAGTCCTGGTTCATTCCCAGAAGGG CACAAA FAM129A ADXCRAG_AL137572_s_at TAATAATAGTATCAGTCGGTGCAACAGTTGGCAACATGTGCCTTCACACTTTACCATAAAGAG SEQ ID ACGGGTTTGAGGGTTTGCCTTCTAAAGTCTGCAACTTCAAGAAAAAAAAATCGACACTGTGGA NO: TTGACTTTCCCGGTCACTATATAAAGCAAATAAACTTAAAACACTTTGTAACCATGTATTTAC 889 TCTGCCAGGTGCCTATATTCCAATAAA FAM129A ADXCRPD.3083.C1_s_at TGAAGATAACATGGCCTTGCCCAGTGAAAGTGTGTCCAGCTTAACAGATCTAAAGCCCCCCAC SEQ ID AGGGTCAAACCAGGCCAGCCCTGCCAGGAGAGCTTCTGCCATTCTGCCAGGAGTTCTGGGTAG NO: TGAGACCCTCAGTAACGAAGTATTCCAGGAGTCAGAGGAAGAGAAGCAGCCTGAGGTCCCTAG 1495 CTCGTTGGCCAAAGGAGAAAGCCTTTCTCTCCCTGG FAM129A ADXCRPD.13585.C1_at ACACCTGGCCTTGGAGTCGCTTTTAAATCTCTTTTACACATCCTGTATTCCAGTCCGTAAATA SEQ ID AACAAATATTTTTTGCTTTCTCCATAGTATATCCAGATTCATTCAGGCCACAACAATCTTTCA NO: TTTGATGTACTCAAGTAAGTTCCCAACTGGTTTTTCTACTTCCCATGCTTACTC 1668 FAM129A ADXCRPD.14825.C1_at GATACCTCAGCCATTAGCAAGCTCTGTCAGTTTTTTTCTTTTCTTATGCCTGTCTTATTCTTT SEQ ID CTCTCTTGGTTTATGCTTCAGAGCACTTGAAAAACCAGTATCACTAAAATCTAATTTTTGTCA NO: AATTATCTTCAAAAATTGTATGGCTCTTTTTATTGTATTGAGTGTCCCTTAACTCTCAGCATT 1759 TTTTGTAGTTTGGCAGTAGACTTTCTGACATTCTCTCTTATTTCCATATCCCAGTGAAATCAT TGTTCCATTTCAGCTAGA FHOD1 ADXCRAG_AB041046_s_at ATGACCTGGTGCAGGCACTGGGACTAAGCAAGGGTCCTGGCCTGGAGGTGTGAAGGTGCTGTA SEQ ID TCCCGGAAATCTATCTGGACCCTGGACTGCAGTGCAGGAGATGACAGAGTGAGGAGGGCCCAG NO: AGCAGAATTCTGGCCCCAGAACTCTGTGCCCAGGAGCCATGCCTTGAGCAGTATTAGCCGTGT 837 GTGTATGCATGTGAGTGTGTGTGTATGTGTGTGTGTGCATGCATATGCATGTGCATGTGTGTG AGCTCCTTGAACGCACGGAGCA FHOD1 ADXCRAD_BU522109_at TGCGCGCCTCTTTCTTGTATCCTCACCCCGATTTGTTACGCCGCTACGCCGCCGCTTCTATAT SEQ ID TCCTTTTCATGCACCGCCTGGCGTCGCCTTTTGCGCGCCGACG NO: 2584 FSCN1 ADXCRPD.10135.C1_at CTGGGCACATGTCCCAAGCCTGTCAGTGGCCCTCCCTGGTGCACTGTCCCCGAAACCCCTGCT SEQ ID TGGGAAGGGAAGCTGTCGGGTGGGCTAGGACTGACCCTTGTGGTGTTTTTTTGGGTGGTGGCT NO: GGAAACAGCCCCTCTCCCACGTGGCAGAGGCTCAGCC 1863 FSCN1 ADXCRPD.10135.C1_x_at GGGCACATGTCCCAAGCCTGTCAGTGGCCCTCCCTGGTGCACTGTCCCCGAAACCCCTGCTTG SEQ ID GGAAGGGAAGCTGTCGGGTGGGCTAGGACTGACCCTTGTGGTGTTTTTTTGGGTGGTGGCTGG NO: AAACAGCCCCTCTCCCACGTGGCAGAGGCTCAGCCTGGCTCCCTTCCCTGGAGCGGCAGGGCG 1864 TGACGGCCACAGGGTCTGCCCGCTGCACGTTCTGCCAAGGTGGTG FSCN1 ADXCRSS.Hs#S2731818_at TTCCAGGCATGATTGCGGGCTTACTTGCTGTCATTCTATTTTTCAGCAAAACTCTGGGTAGGA SEQ ID ATGTCGGAAATTATACCTTTTGAAATCCCTCCTTGAAAACATGGAGATTTGTAGGTATGCAGA NO: GGCAATTGTAACAATATAAAGTATTGTATCTCTTCCACTAGAGTAGGAGGGCCTGACTGTCGG 2092 CCCCTGGGTCTGTCTTCCATTACTTGTCTTGACTTCCGCTGTAAAAGCATTAAGTGGGAAGGT AGCAGTTCTGCTGAACAAGCAGACATTGCCTTCTGTAAG FSCN1 ADXCRAD_AJ708655_s_at CTGTAGTAGCGAGTGATCTGGCGGGGGGCGTCTCAGCACCCTCCCCAGGGGGTGCATCTCAGC SEQ ID CCCCTCTTTCCGTCCTTCCCGTCCAGCCCCAGCCCTGGGCCTGGGCTGCCGACACCTGGGCCA NO: GAGCCCCTGCTGTGATTGGTGCTCCCTGGGCCTC 2701 FSCN1 ADXCRAD_BC004908_at AAACCGTGGACCCCGCCTCGCTCTGGGAGTACTAGGGCCGGCCCG SEQ ID NO: 2875 FSCN1 ADXCRAD_BC004908_s_at GTAAGTGTCATTTGTATAACTCTAAACGCCCATGATAGTAGCTTCAAACTGGAAATAGCGAAA SEQ ID TAAAATAACTCAGTCTGCA NO: 2876 G0S2 ADXCRPD.11190.C1_at GATACAGTTTGTGCCATCAGGGAACACACACACTGTTTGGCAATATAAACTGTATACACCTGC SEQ ID AGAAGAGGGATGAAAGCACCTTTTCCGTATGTATATGATTGCCTTTACCATGTCGTAATGAGG NO: TTTGTGATTTAATTTTCTATTTCTCCCAACATCGAGAACTCCTCCATGGCGAGGATTATTTCT 1438 CACATCCTCTAGCCCTAGCACACTGACTGGAAAATAACTGATGCTCAGGGAGTGTTTGTGAAT GMFG ADXCRPD.1437.C1_at TGATCTCTGGGCTGGGGACTGAATTCCTGATGTCTGAGTCCTCAAGGTGACTGGGGACTTGGA SEQ ID ACCCCTAGGACCTGAACAACCAAGACTTTAAATAAATTTTAAAATGGCGCCAGGCCCCCCCAC NO: GTAAAAGAAAANAACTTGTTCGGCCGCCCTCGGCCCCTCAAAAAACTTTTCTAAACCCTTTCG 1417 TTTGGGCCCCCGGGGCCCACTTAGGTAAGGGAAAAATGGGGCCTAAACCTGTTTCCCTAGGAA AATCCCTTGGCCATGAACTAA GNA15 ADXCRPD.9260.C1_s_at CGGACGGGACCCAGTGATACTTGTATATTACACAGTCCTGATTTCAGACAAT SEQ ID NO: 1400 GNA15 ADXCRPD.9260.C1_x_at TGAGGAGCGGCTCAGTGTCACCTCCCACAGCCACCGGCCCTGACCCTTAATCCAGACACCGAT SEQ ID GGAAGTCGACTTTTCATATCTTTCTCCTGAAATGAACTCTGTTTTAAATTGGAATA NO: 1401 GNA15 ADXCRPD.8623.C1_s_at GCACTCTAGTGGACAGGAGAAGGAACGCCTTCCAGGAACCTGTGGACTAGGGGTGCAGGGACT SEQ ID TCCCTTTGCAAGGGGTAACAGACCGCTGGAAAACACTGTCACTTTCAGAGCTCGGTGGCTCAC NO: AGCGTGTCCTGCCCCGGTTTGCGGACGAGAGAAATCGCGGCCCACAAGCATCCCCCCATCCCT 1404 TGCAGGCTGGGGGCTGGGCATGCTGCATCTTAACCTTTTGTATTTATTCCCTCACCTTCTG GNA15 ADXCRSS.Hs#S1223446_at AGGGACCCTACATCTGGCATCTGGATGTCACCCTGAGCACAGAAGCCTTTCCCCTCACTGGGC SEQ ID CAGGGACACAGATGTTCACCAAGCGTCACTCGCAGGAGTAAACACTGATGCCACAGTTGCTCC NO: CTGCAGGGACCCTCCAGTGACGGCTGCAGAGGGCAGAGTTGCCGGTATCCTCCTGGGGCAGAA 2061 GAGCAGGCGCAGCGCCCTGCCCCGCGTGGTGAGCAGCTCAACCTCACACTCTCAGGCCACGCA CAGGCGGGAGAA GZMB ADXCRPD.5219.C1_at CTATACAAATGTCCCATGGCTACCCCCTACCACTATTAAGTAAATCCCAGCCTCGCCCTCCGG SEQ ID TACTAATACACCACCTAAAACCACTCTTGGTGGCACTGCGCTTCAGANNNNNNNNNNNNNNNN NO: NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAATTTTCCACAGTCCTCTGACGCCCG 1681 ACCCCTGGCTCCTGGTGCAACCCGTCCACCTGGTGAACGTTCATTCTTTCGC GZMB ADXCRPD.5219.C1_x_at TTCCTTTCCCTATACAAATGTCCCATGGCTACCCCCTACCACTATTAAGTAAATCCCAGCCTC SEQ ID GCCCTCCGGTACTAATACACCACCTAAAACCACTCTTGGTGGCACTGCGCTTCAGANNNNNNN NO: NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAATTTTCCACAGTCCTC 1682 TGACGCCCGACCCCTGGCTCCTGGTGCAACCCGTCCACCTGGTGAACGTTCATTCTTTCGC HCLS1 ADXCRPD.1749.C1_at ATAAAAACCTCCTTGTTCGCTGCAGCCCCGGGGGGTGTAAGGGGGAAATTGGCGGCCCTGGGC SEQ ID CATACGGAAAACAAGGCGCCGTGACACTCCAACAGAAGATCGGCACCGTCCCATCCACACGGC NO: TGCAAACTTGCGCCAAAATGCATCTAAACCACGAGAACGCCCGGGGGGGATCCACCCCGCGTG 1483 GGCACGCCGCGGGGAGAGAGGGCGAACGCCGAAACCCAGGTGTGGCGAGCAAAGCTACCCCAT AAAACCT HCLS1 ADXCRPD.6475.C1_s_at GTCCTCTCTATCCTGGATGAGCTCATGAACATTTCTCTTGTGTTCCTGACTCCTTCCCAATGA SEQ ID ACACCTCTCTGCCACCCCAAGCTCTGCTCTCCTCCTCTGTGAGCTCTGGGCTTCCCAGTTTGT NO: TTACCCGGGAAAGTACGTCTAGATTGTGTGGTTTGCCTCATTGTGCTATTTGCCCACTTTCCT 1760 TCCCTGAAGAAATATCTGTGAACCTTCTTTCTG HNRNPA1 200016_x_at AACTCGAGGACTGTATTTGTGACTAATTGTATAACAGGTTATTTTAGTTTCTGTTCTGTGGAA SEQ ID AGTGTAAAGCATTCCAACAAAGGGTTTTAATGTAGATTTTTTTTTTTGCACCCCATGCTGTTG NO: ATTGCTAAATGTAACAGTCTGATCGTGACGCTGAATAAATGTCTTTTTTTTAATGTGCTGTGT 830 AAAGTTAGTCTACTCTTAAGCCATCTTGGTAAATTTCCCCAACAGTGTGAAGTTAGAATTCCT TCAGGGTGATGCCAGGTTCTATTTGGAATTTATATACAACCTGCTTGGGTGGAGAAGCCATTG TCTTCGGAAACCTTGGTGTAGTTGAACTGATAGTTACTGTTGTGACCTGAAGTTCACCATTAA AAGGGATTACCCAAGCAAAATCATGGAATGGTTATAAAAGTGATTGTTGGCACATCCTATGCA ATATATCTAAATTGAATAATGGTACCAGATAAAATTATAGATGGGAATGAAGCTTGTGTATCC ATTATCATGT HNRNPA1 ADXCRAD_CN296684_s_at GAACTGATAGTTACTGTTGTGACCTGAAGTTCACCATTAAAAGGGATTACCCAAGCAAAATCA SEQ ID TGGAATGGTTATAAAAGTGATTGTTGGCACATCCTATGCAATATATCTAAATTGAATAATGGT NO: ACCAGATAAAATTATAGATGGGAATGAAGCTTGTGTATCCATTATCATGT 2549 HNRNPR ADXCRIH.1214.C1_s_at CAAGCTAGTGCTTTGTCTTAGTAGTTTTAAGAAATTAAAGCAAACAAATTTAAGTTTTCTTGT SEQ ID ATTGAAAATAACCTATGATTGTATGTTTTGCATTCCTAGAAGTAGGTTAACTGTGTTTTTAAA NO: TTGTTATAACTTCACACCTTTTTGAAATCTGCCCTACAAAATTTGTTTGGCTTAAACGTCAAA 1302 AGCCGTGACAATTTGTTCTTTGATGTGATTGTATTTCCAATTTCTTGTTCATGTAAG HNRNPR ADXCRPD.2849.C2_at ATCAGGTCCCTTTGTGGACTCTTGCACCTTGCTCCCCTGTTTCTCTCTCTGCCTGTAGGTCTT SEQ ID CATAACTCCACATAAAAATGCACTTTTGTTCTGAACATGTGATAAGTCACTTTCCTTGAACTG NO: CTGTAGTACAGACAGAGCTCCTTCTTCATTAAATTCCCTGAGAGCATCAATTGCTCTTTCATC 1894 AAGATCGACATAAGCTACCAATCCAGGGCAGAGCGGGGGCCGGCAGCCGGGCCCGTGAGAATC AGCGCGAGGCGCTTTGAAAACGACTAGAAATGGCGCGCGCG HNRNPR ADXCRPDRC.2849.C2_at GCATTTCTGTGGCAAACAACAGACTTTTTGTTGGATCCATTCCGAAGAATAAGACTAAAAGAA SEQ ID AACATTTTGGAAGAATTCAGTAAAGTCACAGAGGGTTTGGTGGACGTTATTCTCTATCATCAA NO: CCCGATGACAAAAAGAAGAATCGGGGGTTCTGCTTCCTTGAATATGAGGATCACCAGTCAGCA 2044 AGCACAAGCCAGACGCCGGCTGATGAGTGGAAAAGTAAAAGTGTGGGGAAATGTAGTTACAGT TGAATGGGCTGACCCTGTGGAAGAACCA HNRNPR ADXCRAD_CX788441_at CTTTGGGACCACCAAGAGGCTCTAGGGGTGGCAGAGGGGGTCCTGCTCAACAGCAGAGAGGCC SEQ ID GTGGTTCCCGTGGATCTCGGGGCAATCGTGGGGGCAATGTAGGAGGCAAGAGAAAGGCAGATG NO: GGTACAACCAGCCTGATTCCAAGCGTCGTCAGACCAACAACCAACAGAA 2472 HNRNPR ADXCRAD_CX788441_x_at CTTTGGGACCACCAAGAGGCTCTAGGGGTGGCAGAGGGGGTCCTGCTCAACAGCAGAGAGGCC SEQ ID GTGGTTCCCGTGGATCTCGGGGCAATCGTGGGGGCAATGTAGGAGGCAAGAGAAAGGCAGATG NO: GGTACAACCAGCCTGATTCCAAGCGTCGTCAGACCAACAACCAACAGAACTGGGGTTCCCAAC 2473 CCATCGCTCAGCAGCCGCTTCAGCAAGGTGGTGACTATTCTGGTAAC IFI16 ADXCRIH.3101.C1_s_at ATGTTTCATGCCACAGTGGCAACTGAGAATGAAGTCTTCCGAGTGAAGGTTTTTAATATTGAC SEQ ID CTAAAGGAGAAGTTCACCCCAAAGAAGATCATTGCCATAGCAAATTATGTTTGCCGCAATGGG NO: TTCCTGGAGGTATATCCTTTCACACTTGTGGCTGATGTGAATGCTGACCGAAACATGGAGATC 1195 CCAAAAGGATTGATTAGAAGTGCCAGCGTAACTCCTAAAATCAATCAGCTTTGCTCACAAACT AAAGGAAG IFI16 ADXCRAD_BM806453_s_at TTCTTCTAAAATCTGGATGTCATTGACGATAATGTTTATGGAGATAAGGTCTAAGTGCCTAAA SEQ ID AAAATGTACATATACCTGGTTGAAATACAACACTATACATACACACCACCATATATACTAGCT NO: GTTAATCCTATGGAATGGG 1433 IFI16 ADXCRPD.1023.C1_at GTTCTCCAAAAACGCCCAGTGATAGTGAAGGTACTGAGTACAACAAAGCCATTTGAATATGAG SEQ ID ACCCCAGAAATGGAGAAAAAAATAATGTTTCATGCTACAGTGGCTACACAGACACAGTTCTTC NO: CATGTGAAGGTTTTAAACACCAGCTTGAAGGAGAAATTCAATGGAAAGAAAATCATCATCATA 2268 TCAGATTATTTGGAATATGATAGTCTCCTAGAGGTCAATGAAGAATCTACTGCATCTGAAGCT GGTCCTAACCAAAAATTTGAGGATGGTCCGGCACAGCG IFI16 ADXCRAD_CD252021_x_at GAGCAGAGGCAACTCCTGGAGCTCAGAAAAGAAAAAAATCAACCAAAGAAAAGGCTGGACCCA SEQ ID AAAGGGAGTAAGGTGTCCGAAGAACAGACTCAGCCTCCCTCTCCTGCAGGAGCCGGCATGTCC NO: ACAGCCATGGGCCGTTCCCCCATCTCCCAAGACCTCATTGTCAGCTCCACCCCAAACTTTCTC 2479 AACTGAGAAACCCGAAAACAGTGGCCCAATGTCCAGGTAAACTCCCAGAAA IKZF1 ADXCRAG_BC018349_s_at GGGTTCTTAGTCTCAGCACTATGACATTTTGGGCTGACTACTTATTTGTTAGGCAGGAGCTCT SEQ ID CCTGTGCATTGTAGGATAATTAGCAGTATCCCTGGTGGCTACCCAATAGACGCCAGTAGCACC NO: CCGAATTGACAACCCAAACTCTCCAGACATCACCAACTGTCCCCTGCGAGGAGAAATCACTCC 945 TGGGGGAGAACCACTGACCCAAATGAATT IKZF1 ADXCRAD_BG685498_at GTTAGTATAGAATTCTCGAAACTTGGGAATTCACAAATCAGGACTGGGGACTGCGAGACCACA SEQ ID AATTTCTGATCGCATTTCTGATGGATGTGTCACACCTTTTCTGTCAAAACTAACATGTCTTGG NO: AGGTTAATCGACGTCCCTTGGGTGGACACACACA 2443 IKZF1 ADXCRAD_BG685498_x_at GTTAGTATAGAATTCTCGAAACTTGGGAATTCACAAATCAGGACTGGGGACTGCGAGACCACA SEQ ID AATTTCTGATCGCATTTCTGATGGATGTGTCACACCTTTTCTGTCAAAACTAACATGTCTTGG NO: AGGTTAATCGACGTCCCTTGGGTGGACACACACA 2444 IKZF1 ADXCRAD_BM456472_s_at GTGTGGTGATTGTTCAGGTCGAATCTGTTGTATCCAGTACAGCTTTAGGTCTTCAGCTGCCCT SEQ ID TCTGGCGAGTACATGCACAGGATTGTAAATGAGAAATGCAGTCATATTTCCAGTCTGCCTCTA NO: TGATGATGTTAAATTATTGCTGTTTAGCTGTGAACAAGGGATGTACCACTGGAGGAATAGAGT 2749 ATCCTTTTGTACACATTTT IL27RA ADXCRAD_BG756941_at GCAAGACCCTCAGTACAAAATAAACGTCAGAAACAAAAACAATTAGCTTGGGGCATTATGGCA SEQ ID CACACCTGTTATCCGAGCCACTTGGAAGCTGAGGGGGAGATCGGTTGAGCCAGGAGTTCGAAG NO: TGAGGACTCTGATTGCACATGGATCCAGGTGCGTACCAATGGACTTTTTCAAATA 2631 IL27RA ADXCRAD_NM_004843_at ACACTGCATTTGGGCACCATCTCAGCTCCCTTGCATCCAGGTGCAGCATGGACTGAGTTCTTG SEQ ID ACAACAGAATGTGGTCAGAAGTGACATATGCCAACACGGGGTCTGGGTGGGGGCTCCCCCACA NO: TCCTTTCCTTGCCTATGAGCTGGAACATAACACATGCCTATGATCCAGCTTTGGTCATACCCA 2770 AGGGGAAGGTGGAGCAAGAAATGAAAAGGAACCTGAATCCCTGAATGACTGCATGGATAGAAC CACT IL4R ADXCRAG_NM_000418_s_at GGGACAATTTGCTGCCAAACACCCATGCCCAGCTGTATGGCTGGGGGCTCCTCGTATGCATGG SEQ ID AACCCCCAGAATAAATATGCTCAGCCACCCTGTGGGCCGGGCAATCCAGACAGCAGGCATAAG NO: GCACCAGTTACCCTGCATGTTGGCCCAGACCTCAGGTGCTAGGGAAGGCGGGAACCTTGGGTT 1003 GAGTAATGCTCGTCTGTGTGTTTTAGTTTCATCACCTGT IL4R ADXCRPD.13542.C1_at TCAGCTGACAACAACTTGCATAAGGGCTTACCATGTTAAGGAGCTGTCTTAGATAGCAAATAA SEQ ID ATATTCCAAGCTTATCTCATGTCCAAAACTAACTCCTGATTCCCGCCCCTCCCCAAAGTACCT NO: TCTCTTCTGGCATCCTTCTACATTTCAGAAATGACAACCGCGTCCTTCCCAGTAGTTTAGGTC 1662 AGAAATCTTGGAGTCATCCTGGCCACTTCTCTTTCTCTGTCTTTCACCTCAATTCCAATCTGT CCTCAAATCTACCTCCCAGAGAG IL4R ADXCRSS.Hs#S523708_at CCAGTGGACACAGAATGGAAGGACTGTTCCCAGTTCGGTTTTCAATCAGCAGCAGGCATGCCT SEQ ID TCCAGCAAGCACACCTCATCTCAATACGCCTTCCTGGGCACTTAAGTTCAGGGGTGGAAACAG NO: CTGGGCTGAAGGGGGCTTGGTGGTCTACTGCGACCAGCTCCGTTTCAAAGGTGGGAGGACTGA 2128 GGCCCAGGCAGGGGCAGGAATCCCATCAGATTTGGGAAAATACAGGGCGGCTTCCTC IL4R ADXCRSS.Hs#S3742921_at GATCTGAGCTTGTATTTGGTGCCCAGGACATGTGCTGGGTTCCCGAAATCCCAAAGACACAGA SEQ ID CCCTACCCTCAGGGATTTCTCATTCTAGCAACATAGACTGATCAATTACTGATTATAACGTTA NO: GAAGGCATGTCTGAAGTAGACAGCCATCAGGACATGGTGATTTCAGGCTGGGCTTTGAAGAAT 2185 GACTAGGAGTTTTTCAAGTGTCGAAACTGAACCCTGACCAACCTTTGCTTTTGCAGAC IL4R ADXCRAD_AA767714_at GCCAATGGCAGATGAGAATCAATTCAAAACTTTCCCAAGCACCTGGTTCTGTGCTGGGTTCTG SEQ ID GAGATACAGCCATGGAGACCCTGCCTATGGAGCTCACAGCCCAGGGCAGGAGACACGTGGCTC NO: AACTGATATCCACAGTGCAGGATGAGCAATGCTGAGAGGGCTGTGCGGTGGCAGGGTCAGGGT 2896 ACTGCCAGCTGCCACTGCACCTACCACGTTGAAGAATCTTCTTTCATTGAGTTTTCACGACAG CCCTTACTCCT IL6R ADXCRAG_NM_181359_at ACCACCATCACCAGACAGGTGCGAAAGGATGAAAGTGACCATGTTTTGTTTACGGTTTTCCAG SEQ ID GTTTAAGCTGTTACTGTCTTCAGTAAGCCGTGATTTTCATTGCTGGGCTTGTCTGTAGATTTT NO: AGACCCTATTGCTGCTTGAGGCAACTCATCTTAGGTTGGCAA 1055 IL6R ADXCRAD_BP313907_s_at AAGCACCATAACTTTGTTTAGCCCAAAACCAAGTCAAGTGAAAAAGGAGGAAGAGAAAAAATA SEQ ID TTTTCCTGCCAGGCATGGTGGCCCACGCACTTCGGGAGGTCGAGGCAGGAGGATCACTTGAGT NO: CCAGAAGTTTGAGATCAGCCTGGGCAATGTGATAAAACCCCATCTCTACAAAAAGCATAAAAA 2450 TTAGCCAAGTGTGGTAGAGTGTGCCTGAAGTCCCA INSIG1 ADXCRIH.1510.C1_s_at GAATGACCCCCTTATATATTTTCTGAAAATGAAAACAGTTACATGAAAAAAATTTCCAATGAA SEQ ID GATGTCAGCATTTTATGAAAAACCAGAAGTTATTAGATGAAAGCAGCGAGTGAATCTTTAAAC NO: AGACTTGATCACGCACACACAATAAGTCTTTCTCTCC 1196 INSIG1 ADXCRAD_BU191559_at AATCTATTTAGATCGGGCTGACTGTACAAATGACTCCTGGAAAAAACTCTTCACCTAGTCTAG SEQ ID AATAGGGAGGTGGAGAATGATGACTTACCCTGAAGTCTTCCCTTGACTGCCCGCACTGGCGCC NO: TGTCTGTGCCCTGGAGCATTCTGCCCAGGCTACGTGGGTTCAGGCAGGTGGCAGCTTCCCAAG 2371 TATTCGATTTCATTCATGTGATTA INSIG1 ADXCRAD_BU570382_at GATTTTTTTGCCAATAGTTTATAGAAAATATATGAACCAAAGTGATTTGAGTTTGTAAAAATG SEQ ID TAAAATAGTATGAACAAAATTTGCACTCTACCAGATTTGAACATCTAGTGAGGTTCACATTCA NO: TACTAAGTTTTCAACATTGTGT 2372 INSIG1 ADXCRAD_BU570382_x_at GATTTTTTTGCCAATAGTTTATAGAAAATATATGAACCAAAGTGATTTGAGTTTGTAAAAATG SEQ ID TAAAATAGTATGAACAAAATTTGCACTCTACCAGATTTGAACATCTAGTGAGGTTCACATTCA NO: TACTAAGTTTTCAACATTGTGTTCTTTTTGCATTCATTTTTTA 2373 INSIG1 ADXCRAD_AL541939_s_at TTTTAAATTCTGTGAAAGTGGCTTGATTAAAAG SEQ ID NO: 2611 ITK ADXCRAD_NM_005546_at TGGTATTACCTTTTTCAAGCTCAGATTCATCTAATCCTCAACTGTACATGTGTACATTCTTCA SEQ ID CCTCCTGGTGCCCTATCCCGCAAAATGGGCTTCCTGCCTGGTTTTTCTCTTCTCACATTTTTT NO: AAATGGTCCCCTGTGTTTGTAGAGAACTCCCTTATACAGAGTTTTGGTTCTAGTTTTATTTCG 2767 TAGATTTTGCATTTTGTACCTTTTGAGACTATGTATTTATATTTGGATCAGATGCATATTTAT TAATGTACAGTCACTGCTAGTGTTCAA JUNB ADXCRIH.455.C1_s_at GAAACAGACTCGATTCATATTGAATATAATATATTTGTGTATTTAACAGGGAGGGGAAGAGGG SEQ ID GGCGATCGCGGCGGAGCTGGCCCCGCCGCCTGGTACTCAAGCCCGCGGGGACATTGGGAAGGG NO: GACCCCCGCCCCCTGCCCTCCCCTCTCTGCACCGTACTGTGGAAAAGAAACACGCACTTAGTC 1165 TCTAAAGAGTTTATTTTAAGACGTGTTTGTGTTTGTG KBTBD11 ADXCRPD.18308.C1_at AGGCAGTCTCAGCAATGCCTCTGCCCTCCCTGCAGCAGTCCCAAAATGAACAGCCACACCTTG SEQ ID GAGGGTGTGGCTTTTCTGTTTCATGCGGTGCAAACCCTAGCGGCTCCACACCCCAGGGACTGG NO: CCCCCAAAAAGCAAAAACACTGCTCATGGCTTGGCAGGTCCTCTAGTATGTATTTTTATGTGA 1420 TATCACTATTCAGAACTGTGGTGTATACTATTCTATAAATTTCCACTATAGGTTGGCCGGACA TCCTTTAATGCTGGGTATTAATTCCTCTTATTCT KBTBD11 ADXCRPDRC.18308.C1_at GGTTCATGTGAGATGCAGAGGCAATGAGCTTGAGCCTTCCTACCTTTACTTCCGGCTGGATAC SEQ ID TTGCTCTGGGGAACAATCCCATCAATACCGCAGACGGCTTTGCCGGCCGCCTTCGCCAAAGCC NO: TGGGATTCGGAAACATACGGGGAAACGGGGCGCGGAATCCGAGGAGGGCCACGACAGCGACCA 1927 GGGAGAAAAACGGCAGGTGCGGGAAGAACCTGGGCCACACAACAAAAACACGGAAGTGAGAAC ACCTGGCCACACGAAGGAAGACATGAA KBTBD11 ADXCRAD_NM_014867_at CTTCAGACACGCCAAGTGGATGGATTTGGATTGAACGCATATGAAACAGGAGACGGGTTCTCA SEQ ID TGTGAGATCAAAGCTCCTCCAAAGCCTGTTCAAGCTCTAAGCGATTCTCAAATGTTACCATTT NO: ATTAAAGGTAAACTACACCTGTTGAAGGCCAAGTTCAGGGCAGCTGTTGTGATCTGTGTAGTT 2772 AATGTATTTATTAATGCTTGACTTTTAAAATCCTGGGCATAAATAGTGCAGAGCCTCGTATGT TTGTCAGTTCATGCCGAGATG LARS2 ADXCRAG_BC025989_s_at GATGGCCAGGAATGGACTCATACCATTGGCACATTAGGCTAATCCTGGTTTTATGTGAAGTCA SEQ ID GCAATTAAGTGTTCCCACTAGAACTGACCTAAGCCACTGATTAATATTTAATGAGGGAAGGTA NO: GGGGAGAATCTAGCCATTTTATAATGCCAGAAATCTATATATGTTATCTGATGCCATTTTTCT 950 GAAGTAGCCTCACATGTGGTCCCCCTGCAGTTCAGCAGTTAACAGATGACTTTTTTAGT LARS2 ADXCRSS.Hs#S2986318_at GATGCCACAGCAGATGTGTCAAACCATTTTTCCTGCTCATGGCATGTAGTTTGAGAGAGCTTG SEQ ID ATAGTGAAGCTGCCAGCTCAGCTGTGACTGGCCACTCATTTGCAGACTAGAATGCCTTACTGG NO: CCTGGGCTTGCTTAAGGTAATTGCTTCTAGACTCCTCACTCCTGCTGGGCCACAGTTGCTTGA 2164 ACAGTCAAATAAGGGGTTGGGGGGTAGAGGATATATCTCAAAACCTTCTTTGTGCTTGAAGAT TTGTGATTCCTTGTTCTTTGGAGAA LARS2 ADXCRAD_AK025190_x_at TGTAATCACAGAACATGGGGAAGCTGAGGCAGGCAGATTGCTTGAGGCCAGGAGTTAGAGACC SEQ ID AGCCTGGCCAACATAGTCAAACTCTGTCTCTACTAAAAATACAAAAATTAGCCAGGTGTAGGG NO: GCTCATGCCTGTAATCCTCCCAAGAAGCTGGGCTGAGGCACGAGAATTGCTTGAACCCAAGGG 2820 GCATAGGTTGCAGTGAGCCAAGATCATGCTGCTGCCCTCCAGCTTGGGCAATAAAGCA MAP4K1 ADXCRAD_BG397984_s_at TTCTGGAAGCATGGAGTGCAGGTGTGGGCTCTAGGCTCGGATCAGCTGCTACAGGAGCTGAGA SEQ ID GACCCTACCCTCACTTTCCGTCTGCTTGGCTCCCCCAGGCCTGTAGTGGTGGAGACACGCCCA NO: GTGGATGATCCTACTGCTCCCAGCAACCTCTACATCCAGGAATGAGTCCCTAGGGGGGTGTCA 1070 GGAACTAGTCCTTGCACCCCCTCCCCCATAGACACACTAGTGGTCATGGCATGTCCTCATCTC CCAATAAACATGACTTTAGCCTCTGCAAAA MCL1 ADXCRAG_AF118124_s_at AGTTTTCAATAATTAGGTCTAAGTGGAGTTTTAAGGTTACTGATGACTTACAAATAATGGGCT SEQ ID CTGATTGGGCAATACTCATTTGAGTTCCTTCCATTTGACCTAATTTAACTGGTGAAATTTAAA NO: GTGAATTCATGGGCTCATCTTTAAAGCTTTTACTAAAAGATTTTCAGCTGAATGGAACTCATT 861 AGCTGTGTGCATATAAAAAGATCACATCAGGTGGATGGAGAGACATTTGATCCCTTGTTTGCT TAATAAAT MCL1 ADXCRIH.2623.C1_s_at AGAAGGATGGCGCTCCCAGTGACTACTTTTTGACTTCTGTTTGTCTTACGCTTCTCTCAGGGA SEQ ID AAAACATGCAGTCCTCTAGTGTTTCATGTACATTCTGTGGGGGGTGAACACCTTGGTTCTGGT NO: TAAACAGCTGTACTTTTGATAGCTGTGCCAGGAAGGGTTAGGACCAACTACAAATTAATGTTG 1101 GTTGTCAAATGTAGTGTGTTTCCCTAACTTTCTG MCL1 ADXCRIH.2463.C2_at CATAAGCCGCTTATTTATATCATGTATCTCTAAGGACCTAAAAGCACTTTA SEQ ID NO: 1267 MCL1 ADXCRIH.2463.C2_s_at TCTTAAGATCTGGTTACGGTAACTAAAAAAGCCTGTCTGCCAAATCCAGTGGAAACAAGTGCA SEQ ID TAGATGTGAATTGGTTTTTAGGGGCCCCACTTCCCAATTCATTAGGTATGACTGTGGAAATAC NO: AGACAAGGATCTTAGTTGATATTTTGGGCTTGGGGCAGTGAGGGCTTAGGACACCCCAAGTGG 1268 MCL1 ADXCRPD.7685.C1_s_at GCAACCACGAGACGGCCTTCCAAGGCATGCTTCGGAAACTGGACATCAAAAACGAAGACGATG SEQ ID TGAAATCGTTGTCTCGAGTGATGATCCATGTTTTCAGCGACGGCGTAACAAACTGGGGCAGGA NO: TTGTGACTCTCATTTCTTTTGGTGCCTTTGTGGCTAAACACTTGAAGACCATAAACCAAGAAA 1835 GCTGCATCGAACCATTAGCAGAAAGTATCACAGACGTTCTCGTAA MCL1 ADXCRAD_BP365482_s_at AGGAGATGGAAGCCCCGGCCGCTGACGCCATCATGTCGCCCGAAGAGGAGCTGGACGGGTACG SEQ ID AGCCGGAGCCTCTCGGGAAGCGGCCGGCTGTCCTGCCGCTGCTGGAGTTGGTCGGGGAATCTG NO: GTAATAACACCAGTACGGACGGGTCACTACCCTCG 2345 MCL1 ADXCRAD_BQ962674_at ACCATGGTGCTATTATTAGGCTTGCTTGTTACACACACAGGTCTAAGCCTAGTATGTCAATAA SEQ ID AGCAAATACTTACTGTTTTGTTTCTATTAATGATTCCCAAACCTTGTTGCAAGTTTTTGCATT NO: GGCATCTTTTGGATTTCAGTCTTGGATGTTTGTTCTATCAGACTTAACCTTTTATTTCCTGTC 2346 CTTCCTTGAAAATTGCTGATTTGGTTCTGCTCCCTCTACAGATAATTTATATCAATTTCCCTA CAGCCTTTC MCL1 ADXCRAD_CX866513_at TTGGCAGACAGGCTTTTTTAGTTACCGTAACCAGATCTTAAGATTAATTAAAAACTACATAAA SEQ ID GTGCTTTTAGGTCCTTAGAGATACATGATATAAATAAGCGGCTTATGATCAAGAACGATAAAT NO: ACATAGGTAAAAATAGCTCTAGCAAAGATGACCTTATGGCTCTGAGATGGGCAGGCAGGGCAA 2558 TTCTTCCCCATTACATTCTTAGTCATCTTATTCATACCTATTTTTAAATGGAGTCCACAGACT AAAGGTCATGTTCCGAGACTGAAGCTTTCAAATGACCCTAGTTCCAAT MCL1 ADXCRAD_BF981280_at AACCATAGGCGACAGCGGACACCAACAAACGAGCAGAAACTCCACCAGCTGAAACGCAGCCAT SEQ ID GCAGAGCAAACACAGAGCAACCACGCATCATCATACAAAAAGCCAGAGCCACCACGGAACCCA NO: TACACGAAACAGTAACAACAAGCAGCACAACAACACCGCCGTCCGACACACACGTCGATCAAA 2667 TACAGACACCGATAGCAAAACATAGCAACAACGAGAGCGAATCGAAAGCCTCAACGCCTCAAC CCCCTAGTCAGTCCCACGCCACATATACG MCL1 ADXCRAD_BF724558_at GCCCGACCCGGAGAGCTGTTTCTTAATCTGCCTGGAGGAAAATCCCAGCCCCCAAATTTCCAC SEQ ID ATACTTCACATAGATAACACTGTAACAACTTTGAAACTAAGAGGGAGAGA NO: 2841 MCL1 ADXCRAD_BF724558_x_at CCCAGGCCCCGGAGTGCAATGGCATGATCTCAGCTCACTGCAACCTCCGCCTCCCGGGTTCGA SEQ ID GCGATTCTCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCCTGAGCCACAGCGCCCGAC NO: CCGGAGAGCTGTTTCTTAATCTGCCTGGAGGAAAATCCCAGCCCCCAAATTTCCACATACTTC 2842 ACATAGATAACACTGTAACAACTTTGAAACTAAGAGGGAGAG MFNG ADXCRPD.17460.C1_x_at TGGCAATTGGCACTGAAGGCACCCAAGCCCCTGGAGCCTTTCTTGCGGTTAGGGCTAACATGG SEQ ID ACCAGCTTTGGCAGAGGAACTAAGCAATCCAATAAGATGTTCTTGGAAAGTTTTGAGCCACTC NO: CCATCTTCTGGCAAAATGTGGGTTGAAGGCGGATCT 1873 MFNG ADXCRPDRC.7895.C1_s_at AACCCAAGGGCGCTGCTGCAGCTTCTGAGAGCCTTCCCGCTGGCCCGCGACGTCTATGTGGGA SEQ ID AGGCCCAGCCTGAACCGGCCCATCCATGCCTCAGAGCCACAGCCCCACAACCGCACGAGGCTG NO: GTACAGTTCTGGTTTGCCACTGGGGGTGCTGGCTTCTGCATCAATCGCAAACTGGCTTTGAAG 2043 ATGGCTCCGTGGGCCAGTGGCTCCCGTTTCATGGACACATCTGCTCTCAT MFNG ADXCRAD_NM_002405_at ACGGGTCCCAGCCAATTGTGATGATCCTTTTTGCTCATTTCCCAGCCTTTCTTGCTGTTAGGG SEQ ID GCTACCATGGGACCAGCTCTGGCCAGAGGGAACTAAGCAAATCCAATAGAGATGTTTCTGGGG NO: AAGGTTTTGCAGCCCACTCCCCATCTTCCTGCTATAAATGTGGGTGTGATGGCTGGATCTGGG 2775 GCAGCCACCTTGCTACCATGAAGGAAAGGCCAAGACAATCATCCACAGCTATTCCCTCCAGCA TCTGGTTCTGTACAAAAATTA NAP1L1 ADXCRIH.187.C2_s_at TGAAAACTTCCTTTCTGAGAAGTTAGTGTTAAGGTCTTGGAATGTGAACACATTGTTTGTAGT SEQ ID GCTATCCATTCCTCTCCTGAGATTTTAACTTACTACTGGAAATCCTTAACCAATTATAATAGC NO: TTTTTTTCTTTATTTTCAAATGATTTCCTTTGCTTTGATTAGACACTATGT 1301 NAP1L1 ADXCRPD.3079.C1_s_at TCAAAGATAGAATCCCATTTTTAATGAACTGAAGTAGCAAAATCATCTTTTTCATTCTTTAGG SEQ ID AAATAGCTATTGCCAAAGTGAAGGTGTAGATAATACCTAGTCTTGTTACATAAAGGGGATGTG NO: GTTTGCAGAAGAATTTTCTTTATAAAATTGAAGTTTTAAGGGACGTCAGTG 1494 NAP1L1 ADXCRPD.367.C1_s_at AGTGAAGTTCTCAGATGCTGGCCAGCCTATGAGTTTTGTCTTAGAATTTCACTTTGAACCCAA SEQ ID TGAATATTTTACAAATGAAGTGCTGACAAAGACATACAGGATGAGGTCAGAACCAGATGATTC NO: TGATCCCTTTTCTTTTGATGGACCAGAAATTATGGGTTGTAC 1910 NAP1L1 ADXCRAD_BP220549_at AGTTACTGGTACCACAGTGAGGTGAATAAAACGGGATTTTCAGAAGTTAGCCTGAATTTAACT SEQ ID GTATTTTTAAATTTAACCTCCATTAACTAAGCATCTTTTCTTTGTGGTAGGGTCTACCTTCTG NO: CTTCCCTGGAAAGGATGAATTTACATCATTCGACAAGCCTATTTTCAAGTTATTTGNTGGTTG 2470 TTTGCTTGTTTTTGTTTTTGCAGCTAAAATAAAAATTTCAAATACAATTTTAGTTCTTACAAG ATAATGTCTTAATTTTGTACCAATTCAGGTAGAAG NAP1L1 ADXCRAD_BP220549_x_at AGTTACTGGTACCACAGTGAGGTGAATAAAACGGGATTTTCAGAAGTTAGCCTGAATTTAACT SEQ ID GTATTTTTAAATTTAACCTCCATTAACTAAGCATCTTTTCTTTGTGGTAGGGTCTACCTTCTG NO: CTTCCCTGGAAAGGATGAATTTACATCATTCGACAAGCCTATTTTCAAGTTATTTGNTGGTTG 2471 TTTGCTTGTTTTTGTTTTTGCAGCTAAAATAAAAATTTCAAATACAATTTTAGTTCTTACAAG ATAATGTCTTAATTTTGTACCAATTCAGGTAGAAG NAP1L1 ADXCRAD_CX870261_s_at CAAGGGACGTGGGACAGTTCGTACTGTGACTAAAACAGTTTCCAATGACTCTTTCTTTAACTT SEQ ID TTTTGCCCCTCCTGAAGTTCCTGAGAGTGGAGATCTGGATGATGATGCTGAAGCTATCCTTGC NO: TGCAGACTTCGAAATTGGTCACTTTTTACGTGAGCGTATAATCCCAAGATCAGTGTTATATTT 2555 TACTGGAGAAGCTATTGAA NAP1L1 ADXCRAD_BQ884238_at GACTATGACCCAAAGAAGGATCAAAACCCAGCAGAGTGCAAGCAGCAGTGAAGCAGGATGTAT SEQ ID GTGGCCTTGAGGATAACCTGCACTGGTCTACCTTCTGCT NO: 2641 NARF ADXCRAD_CN367752_s_at GGAGGTCCTCGCCTGTGCTGGAGGATGCTTAAATGGCAGAGGCCAAGCCCAGACTCCAGACGG SEQ ID ACATGCGGATAAGGCCCTGCTGCGGCAGATGGAAGGCATTTACGCTGACATCCCTGTGCGGCG NO: TCCGGAGTCCAGTGCACACGTGCAGGAGCTGTACCAGGAGTGGCTGGAGGGGATCAACTCCCC 940 CAAGGCCCGAGAGGTGCTGCATACCACGTACCAGAGCCAGGAGCGTGGCACACACAGCCTGGA CATCAAGTGGTGAAGTCAGGCCAGGGCCTT NARF ADXCRSS.Hs#S2978401_at GAAACAGTACTTGGATCCACATCTTAGTCAAATTATTAAAATACAGCAGACAAGGACAGGATC SEQ ID ATAGTCCTCATCTTTCTCTCTTCCCCCACATTAATACATTATTATTTCAATGAAATGAGCCAA NO: ATTTTAAACCTAAACTACTTATGTACTCTTGCAAATTTTCTGATAATTTTTAATATAAATTCA 2147 AAACATAAATTCATTTTGAAGTTGGAATTTGAATAAACTCATTGTGGTTCAAATAAGAGACCA ACGAC NFIL3 ADXCRAD_BG925633_s_at GAGACTTATAGCCACACAACCAATCTCTGCTTCAGACTCTGGGTAAATTACTACTGAGTAAGA SEQ ID GCTGGGCATTTAGAAAGATGTCATTTGCAATAGAGCAGTCCATTTTGTATTATGCTGAATTTT NO: CACTGGACCTGTGATGTCATTTCACTGTGATGTGCACATGTTGTCTGTTTGGTGTCTTTTTGT 1805 GCACAGATTATGATGAAGATTAGAATGTGTTATCACTCTGCCTGTGTATAGTCAGATA NFIL3 ADXCRSS.Hs#s5972058_at GGGCCGAAGTGATGATGTATCTAATATTATATCCTAGAACATTCACAGAGTAGCTGCAGAATG SEQ ID TCTTGAGCTGGAACATCCCCAAGAGGCCATATATATATCCCAGGGATTTTACAGTGGACCTCA NO: CTAGGCCGGAGTAACTGTAAAGTCAGATGGATAATGAGAATTCAGGACGTTAGCCACACGTGG 2062 ACTGTGGCAAAAAGAAAGTGACCCACTGAAGAAGACTGTTTTTCAGCTCTCTCATCAATTGCT GTTTCCAGGAGCCCACAGCTCCAATTACTCAAAAGA NFIL3 ADXCRAD_AK095268_x_at GGAGATCAAAACCATCTTGGCCAACATGGTGAAATCCCATCTCTACTAGAAAATACAAAAATT SEQ ID AGCTGGGTGTGGTGGCATGTGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGCCAGGAGAATTA NO: CTTGAACCGGGGAGGTGGAGGTTGCAGTGAGCCAAGATCACTCCACTGCACTCTAGCCTGGTG 2795 ACAGAGCGAGACTTTGTCCCAAA PDE4DIP ADXCRAG_BX647660_s_at GCCAGACCAACTCTGTTGAAATTCTTGCATAGAGCAAACCTGTGCTCATTTTTAAGTGGCATG SEQ ID GGAGAGGCCCCAAGCCTAGTAAAGCCTAGTCTGTGTCTTCACAGTGCTGGTAGAATGTGTTCG NO: TGTGTATAAATATATGATATAGATTTATATATGTTGCTAACGCCATATATTGAAGGCCAACAT 983 AACTGGTGGACAGGGT PDE4DIP ADXCRPD.5634.C1_at CACGGGTTCTTATATGAAGATACACTTATAATCTGGTATGTTACCTGGTCAAGAGGAAATTCA SEQ ID ATATACAAGACAGGCATGAACCTTGGAGCACTTCTTCCTGACAGTATAAGTGAACTTAAAAGG NO: ACGTCAAGTGCCAATAGGAACTTACATACAAGCAGCCAGAGTACAGTCCCATATGGGAGATAA 1739 CACGAAATCACTAATCCTTCTTCTTTTCTTTGCTTTTGCTATCATAGTCTCGAA PDE4DIP ADXCRAD_CK002790_at TCTTCATTTTAGAATGTTATCTTGGTATGTTTAAAAGGAAAAACTTAAGATGTGTTGCAATTG SEQ ID CAGTATGAGTTTCAGGTATGTACATGTTATGTGTGTGTGTGAGAGACACACACAAACACATTT NO: CAAACATGTTTTATGTTTAAGCTCAATATTCAAACACAGAAATATAACATCTATTCTTAATAT 2498 GTTTTATGTAAGTACAGCAGCAGCATTATTAAATACTGTATTTCTATGGTGATTGAAAATTAG TANGCAGAGAATTTTGTATGGGTCTTAATATTTTTGTATA PDE4DIP ADXCRAD_CK002790_x_at TCTTCATTTTAGAATGTTATCTTGGTATGTTTAAAAGGAAAAACTTAAGATGTGTTGCAATTG SEQ ID CAGTATGAGTTTCAGGTATGTACATGTTATGTGTGTGTGTGAGAGACACACACAAACACATTT NO: CAAACATGTTTTATGTTTAAGCTCAATATTCAAACACAGAAATATAACATCTATTCTTAATAT 2499 GTTTTATGTAAGTACAGCAGCAGCATTATTAAATACTGTATTTCTATGGTGATTGAAAATTAG TANGCAGAGAATTTTGTATGGGTCTTAATATTTTTGTATA PDE4DIP ADXCRAD_BG192476_s_at AATGCTGGGAAGTCCTAACCACATCAAGAATGCCTCAGATCAGTGACC SEQ ID NO: 2630 PDE4DIP ADXCRAD_H24473_at AACTCATACTGCAATTGCAACACATCTTAGTT SEQ ID NO: 2888 PDE4DIP ADXCRAD_H24473_s_at GCCTACTAATTTTCAATCACCATAGAAAATACAGTATTTAATAATGCTGCTGCTGTACTTACA SEQ ID TAAAACATATTAAGGAATAGATGTTATATTTCTGTGTTTGAATATTGAGCTTAAACATAAAAC NO: ATGTTTGAAATGTGTTTGTGTGTGTCTCTCACACACACACATAACATGTACATACCTGAAACT 2889 CATACTGCAAT PHF11 ADXCRIH.2487.C1_s_at TTCCTAAGCCAAGAGTCATGTCAAATTGCAATCAGGCTCAAAACCAGAGACCAGGCTGTGAAA SEQ ID TCCACACATCTTTAGAACTAGTCGTCTCCTCTTGGCCTCAGCAGCTCTTCCCTGTTCTTACTG NO: GTTGACATTTTGATCACTCTTTGCACACTCTTGTGTTTTTTGCTCACTGTCACACTCCCAGCA 1161 CCTAGTATGCTCAGTAAATGTTTGTGGAATAAGTGCATAAAATGTTCTTAACCTTTGATTCTA CTTACAGCCCATGATAGCCTCTTAGATA PHF11 ADXCRAD_BE621153_at AAAACAATCGGAACACAAGTCAGTAATTAGTAGACACAGCAGATCGTACCAACGGCCGGCTAA SEQ ID AGGGCCCGACACTAAAATACCATCGACCACACCACGAGCCAAACACACACAACGGGCA NO: 2595 PLAGL1 ADXCRPD.569.C1_s_at TTTTCTTTGCTCTGTCTAGCTTAAACTACTACTCAAGCTGCTTAAGTTCTTAAGTATTGTTTG SEQ ID TAATCACCAATAAATAAGTGCATTTGTAATTCATCAGTCATTATTAGCTTTTATTAAAAGAAG NO: ATTACGTTTTACAATGTAACTATAATCTCTTGAATTTGGTATCTTATTAATGAGTTTTAAAGA 1565 TGTAAAACCTAACCTTTTTTAAAGCTCCATTGTCTTATGTTT PLAGL1 ADXCRAD_CA942280_s_at ATGATATACTATGACTAGGCTGTGTATTTCTTTTCAGGGATTTTTCTACCTTCAGGGTTGGAT SEQ ID GTAGTTTAGTTACTATTACCATAGCCAACCTGTAGTTTTACATATACATTTTCTTGTGGAGCA NO: ATAGAGTTCTCCATTTTACAGAAGCATTTTAAATGTAGTTTGAATATTTTCCACAAGATGCTG 2495 CAATGTGAGTTATCACTTCATTTATCTTA PMAIP1 ADXCRAG_BC013120_at GGAACAGTTAGTTCTCATCTAGAATGAAAGTTCCATATATGCATTGGTGAATATATATGTATA SEQ ID CACATACTTACATACTTATATGGGTATCTGTATAGATAATTTGTATTAGAGTATTATATAGCT NO: TCTTAGTAGGGTCTCAAGTAAGTTTCATTTTTTTTATCTGGGCTATATACAGTCCTCAAATAA 936 ATAATGTCTTGATTTTATTTCAGCAGGAATAA PMAIP1 ADXCRPD.936.C1_at GATTCAGAAGTTTCTGCCGGAAGTTCAGTTTGTCTCCAAATCTCCTGAGTTGAGTAGCACACT SEQ ID CGACTTCCAGCTCTGCTGGAGCCCGCGCGGGGCTCGGTTGAGCGTTCTTGCGCGCCTTCTTCC NO: CAGGCATCTCCGCCGGTGCCGCCGCCCACTCAGCTACAGAGCCCGGGAACCTCAGCCTCCAAC 1633 TGGAGCACCTCGGACAGCTGCAGGACGCGAGCTGAACACGAACAGTCCTGCAGGCAGGGATGG GGAATCGGGTGTCCGGACGCGCGAT PMAIP1 ADXCRPDRC.936.C1_s_at CTTGGGGCCAGTAAATCAGTAGACTGAACATTCAATATAATAAAAGAACATGGGGATTTTGTA SEQ ID TAACCAGGGATAATAAAAAGAAAACAGAAGTTGATTTTTAATTGATGTTTTTGAAACTTAGTA NO: GAACAAATATTCAGAAGTAACTTGATAAGAAATGAATGTTTCTAAAGAAGTTTCTAAAGATTC 1977 GGAAAATGCTCCTTGTCACATTAGTGTGCATCCTACAAAAAGTGATCTCTTA PNMA2 ADXCRAG_XM_376764_s_at TATTTTTTCTGATTGTGGTTCAGTTTAACTGAAGAATATCCTGAGATTGTAAGAAAAGCATTT SEQ ID TTTAAAAGGTATCACTTGTGATCATTTATCTTTCTAAATTCTATTTTTAATACTGTTCCACCA NO: AAGTGATGCAGTGGTTACCATGACACCCTAATTTCATGTGTTTTTGTATTTATGAAAATAGTT 1092 TCATTGTCATTTATTGGCGGTAT PNMA2 ADXCRAD_BU073065_s_at CCTGGGGGCAGGACCCACAGCCAGTGGGCTAAGACCTTTAAAAAATTTTTTTCTTTAATGTAT SEQ ID GGGACTGAAATCAAACCATGAAAGCCAATTATTGACCTTCCTTCCTTCCTTCCTTCCCTCCCT NO: TCCTCCTTCTCTCCTTCTCTCCTCCTCTCTCCTCTCCTCTCCTCTCTTTCCTTCCTTCCTTCC 2647 TTTTTTTCTTTTTCTCTTTCTTCTTTATTTCTTGGGTCTCACTCTCATCACCC PPRC1 ADXCRPD.9220.C1_at CAGGTATTGAAACAAGTTAACTTGCATTCCTATGTAAGATAGGAGGGGCTGAGGGGATCCCCA SEQ ID GTGTTTGGAACATAAGTCACTATGCAGACTAATAAACATCAACTAGAG NO: 1398 PPRC1 ADXCRPD.9220.C1_x_at TCCCTGCTATCCTTTTTCTCCTTTGGAGGTGCNCCAACCTCCTCCACCCCCTTCCCCTACTCT SEQ ID AGGGGAGAGAGCTGCTAGTGAGATGACTGTTTTATAAAGAAATGGAAAAAAGTGAAATAAAAA NO: ATATGTTGAATCAGATTTTTTAAAAGGGGTATTTGTTTTTTTATAACAGGTATTGAAACAAGT 1399 TAACTTGCATTCCTATGTAAGATAGGAGGGGCTGAGGGGATCCCCAGTGTTTGGAACATAAGT CACTATGCAGACTAATAAACATCAACTAGAG PPRC1 ADXCRPD.16668.C1_at AGGGCTTCACTGCAGAGCTGTCTTCTTGGCTGGGGCTGGTGGGATGACAAGACAAGGGATGTC SEQ ID TGCCAGCCCTGTGGGAGTCTCTGGAAGGCTAGGCCACTTCCCAGTTGGGGGCTGTGGACTTCT NO: CTCTTCTGTTTCTGCTTGGCGTTGCTGCCTTCGTCGCCGGTACTCAGATAAGCTGAGAGGCCG 1832 AGGTCTGGCTTCATGGGTTGTAGCACTGGTACCACTTTCAATTTTCA PPRC1 ADXCRPDRC.16668.C1_at GAAGAGAGAAGTCCACAGCCCCCAACTGGGAAGTGGCCTAGCCTTCCAGAGACTCCCACAGGG SEQ ID CTGGCAGACATCCCTTGTCTTGTCATCCCACCAGCCCCAGCCAAGAAGACAGCTCTGCAGTGA NO: AGCCCTGAAACACCCCTTGAGATTTGCCTTGTGCCTATAGGTCCCAGCCCTGCTTCTCCTAGT 2033 CCTGAGCCACCTGTAAGCAAACCTGTGCCTCATCTCCCACTGAGCAGGTGCCATCCCAGAAGA TGCCACTGTTGGCGAGACCTT PRF1 ADXCRAD_BQ654088_at TTCTTTGGCCTTAATGGGAGCCCATCAACTTCAACTGCTCGTGGCTTCTTTGCCCACATGCTT SEQ ID TTCCCCTGAAAAAAAATGGAGGGCCGGCCCTGACCTGGCCTCACAATGAAACTAAA NO: 2314 PRF1 ADXCRAD_BQ654088_x_at TGCAGTCACAGCTACACAGATCACAGCTTCAGCCAGGAGCTGGGCAGAAAGCCAAGAGGCTGT SEQ ID TCCCACCAGGCTGCTCAGGGCTGGTCTTTTAGGACCCTTTCCTTGGACCCCCTATGGTGGGGG NO: CAAAACTTTCTTTGGCCTTAATGGGAGCCCATCAACTTCAACTGCTCGTGGCTTCTTTGCCCA 2315 CATGCTTTTCCCCTGAAAAAAAATGGAGGGCCGGCCCTGACCTGGCCTCACAATGAAACTAAA PRF1 ADXCRAD_A1445650_at TTATGGGCCCTTTATAAAGCTATGTACATGGGGAAACAGGTCAGGACAGGCCTCCTTTTGTTT SEQ ID AAGGGGCAAAGCATTGGGGGCAAAAAAAACAAACCAGTTGGAGCTGATGGGGCTCCAGTTAAG NO: GCAATGAAGGCTTTGCCACACCATAAAGGGCTCAGGGGAAGGGTCCTAAAAAACCACCCCTGA 2881 GCAGCCTGGGGGGAACAGCCTTTTGGCCTTCTGCCCAGCTCCTGGCTGAAGCTGTGATCTGTG TACCTGTGACTGCAGGGCTTGAAAATGGCGGAGGGCTTAGGCAGT PRKCQ ADXCRAG_NM_006257_at CTGTTTGCAGCAGTCAATTGAGTTGAATTAGAATTCCAACCATACATTTTAAAGGTATTTGTG SEQ ID CTGTGTGTATATTTTGATAAAATGTTGTGACTTCATGGCAAACAGGTGGATGTGTAAAAATGG NO: AATA 1032 PRKCQ ADXCRAD_AA234512_s_at AAGGTTTGCTAGACACCTTCGCTTGTTATCTTGTCAAGATAGAAAAGATAGTATCATTTCACC SEQ ID CTTGCCAGTAAAAACCTTTCCATCCACCCATTCTCAGCAGACTCCAGTATTGGCACAGTCACT NO: CACTGCCATTCTCACACTATAACAAGAAAAGAAATGAAGTGCATAAGTCTCCTGGGAAAAGAA 1033 CCTTAACCCCTTCTCGTGCCATGACTGGTGATTTCATGACTCATAAGCCCCTCCGTAGGCATC ATTCAAGATCAATGGCCCATGCATGCTGTTTG PRPF3 ADXCRAG_AF016370_s_at GCATGGGGCTGAACACTACTGGGACCTTGCGCTGAGTGAATCTGTGTTAGAGTCCACTGATTG SEQ ID AGACTACTGCAAGCCCTTGCCTCTCCTCCCTTGCCTTTGTCTCTTCAGTCCTCTCACTTATTC NO: TATTTCCCAACCCCCTCCCACTTGTTTGTGTGATCTCAGAACTGTGCCAAGCAGACACTGGGA 844 CAAAGGGAGAATATCTTGCTCCCCTCCTGAGTCAGCCTGGTGTTGCCCTTTATTCCCCTTATG TGCATA PRPF3 ADXCRAD_BG680099_at ACCTAGCGGACGTCTCTCTATAAAAGCGAGAGTGACGCGCCCGGTGTAAAAACCAACGCACGG SEQ ID GGACAGCAGAGACAAACTATGTCTCCTAGTGGTGCATCACCTTTGAGAAGGAACACACATCAT NO: ACGGCGTGGCGGAGACACACATATAGGAAACCACCCCTCAACGCAGGTAATAAGTGGCCAGGA 2389 GGGAACATATACAGCTCGTGAGAGGCATATTAGGGGAGCAGCCGACCCCGCTACCCTCTGCCC GGCGTCAAAAATTATCCATGGCGGATTCTGTGAACTCA PSMB10 ADXCRIH.3674.C1_at TCGCGGCCCGTAGATAACGCGTGTAGCTCCATCTTGGACGCCACCATCCGTGTGGTCATCTCG SEQ ID GCGTCCGCGGCTACTCCAGCCCCACAGCAGTAGATTTTGGGGGCGATGAAGTGGATCTTCTCG NO: CAGCTCTTGTCCGCCACGACCGAATCGTTAGTGGCTCGCGTATCGGCGCCCAGAATGACCCCC 1114 GTCTTGGAACACCAAGCCCGCGATGGTGGTCCCGGTCTTGCGTGCGTGAAGGGACCTTGAGCC CCGGGAGGACGCGTTCCAATGATGCATTTT PSMB10 ADXCRIHRC.3674.C1_s_at TCACCGCCGGGATCTTGGGTGACCTGGGCTCCGGGGGCAATGTGGACGCATGTGTGATCACAA SEQ ID AGACTGGCGCCAAGCTGCTGCGGACACTGAGCTCACCCACAGAGCCCGTGAAGAGGTCTGGCC NO: GCTACCACTTTGTGCCTG 1307 PSMB8 ADXCRAG_557528_s_at CTGGGCGGTCATGGCGCTACTAGATGTATGCGGAGCCCCCCGAGGGCAGCGGCCGGAATCGGC SEQ ID TCTCCCGGTTGCGGGAAGCGGGCGTCGCTCGGACCCAGGACACTACAGTTTCTCTATGCGATC NO: TCCAGAGCTCGCTTTA 1082 PSMB8 ADXCRIH.1957.C1_at TCAATCTGAACGTTCCTTTCTCCGTCCCCACCCAGGGACTGGAAGAATTCTGTGGGCTCCAGG SEQ ID CCCGGGCATCCGCTGGAAACAGGGGTGGGTAGGGTCGTGTCATCTAAAGGCGCAGCTTCAACC NO: AGAAGACTAGAAGTCAGCCAGGAGCTGGGAGTAGTGTCACGCGGGGTGGGGGTTCCTATGAGC 2244 ATCACTTTACAAAACCAGGAGGGACGGAAGTGCGAGGGGGCAGAGTCTTGGAAACAGGTCCTG GGCCAACTGCAACAGAATATACCCGCCGCGTGTA PSMB8 ADXCRIH.1957.C2_at GAGGCGTTGTCAATATGTACCACATGAAGGAAGATGGTTGGGTGAAAGTAAAAGTACAGATGT SEQ ID CAGTGACCTGCTGCACCCGTACCGGGAACCAATCAA NO: 2245 PSMB8 ADXCRIH.1957.C2_s_at TCTCCACGGGTAGTGGGAACACTTATGCCTACGGGGTCATGGACAGTGGCTATCGGCCTAATC SEQ ID TTAGCCCTGAAGAGGCCTATGACCTTGGCCGCAGGGCTATTGCTTATGCCACTCACAGAGACA NO: GCTATTCTGGAGGCGTTGTCAATA 2246 PSMB9 ADXCRPD.891.C1_at CCGGCAGCACCTTTATCTATGGTTATGTGGATGCAGCATATAAGCCAGGCATGTCTCCCGAGG SEQ ID AGTGCAGGCGCTTCACCACAGACGCTATTGCTCTGGCCATGAGCCGGGATGGCTCAAGCGGGG NO: GTGTCATCTACCTGGTCACTATTACAGCTGCCGGTGTGGACCATCGAGTCATCTTGGGCAATG 1618 AACTGCCAAAATTCTATGATGAGTGAACCTTCCCCAGACTTCTCTTTCTTATTTTGTAATAAA CTCTCTAGGGCCAAAA PSMD11 ADXCRIH.2540.C1_at CCACGTCGGCCTTGGAGAGTTTGATGAGACTAGATATGTGTTCAATCTGTACTCTGGAAAAAG SEQ ID GCTCAATGACTCGGATCAGATTCTGTTCTAGTAAGTTATCATACAACTTGGCCAAGTGTGTGC NO: TGATGATTGGGTCATCCCGGAGCTCTGCCCGGTAATCTGTCAGAGCCTTTTCAAAATCTGCCA 1210 GTGATCTGTTCTTGCTAGCCCTGAGCTCACGCATTTTAATGCTTTCTGTCTGCCTCCCTGCAT ACCGAATGCAAG PSMD11 ADXCRIHRC.2540.C1_at AGCTCTGTCTTTTGCGTGTCGAGACTGAAAACCTCCTCCTGGTGTCCTCATGGCTTCCTGATT SEQ ID GACACTGCTCTGT NO: 1322 PSMD11 ADXCRIHRC.2540.C1_x_at AGCTCTGTCTTTTGCGTGTCGAGACTGAAAACCTCCTCCTGGTGTCCTCATGGCTTCCTGATT SEQ ID GACACTGCTCTGTCTTCTCTTGCAGAGTTGGATCTGTAGCGGTCCTTTGGAGAGTGTGTGTGG NO: CGGGAGAGTGAAACCTTGGGGGAAAATGCTAGGAGATTCTTTTTTCTTTTTGTTCTACTTTTC 1323 GCTCGGAAAGTTTTTAAATCCTCATTTGGTGCATCTGTATTCCAGCCAATAGGTGTGCCAGTT TTCATGTAATCTTTACTGGCCCAACTTG PSMD11 ADXCRPD.139.C1_at GGACCGGGGCAGAATTAACGTGCAAAGAAATGGGTTGGTGAAGTTTTCTTTACAGGCCCTTTC SEQ ID CGGGGCGGCCCGCTGGAAGACCCCTTCCGCCAACACGGGCTCTTCAACGGAAGCCCGGGAAAT NO: CGCCCGCGGGCGCATTACCACACGCCCGCCGCCGCGCGCATCCGCATATATAAATACTCTGGC 1903 CCCCAGAGGG PTPN2 ADXCRIH.138.C1_at GCAAAGCAAGACCTGAAGCCCACTCCGGAAACTAAAGTGAGGCTCGCTAACCCTCTAGATTGC SEQ ID CTCACAGTTGTTTGTTTACAAAGTAAACTTTACATCCAGGGGATGAAGAGCACCCACCAGCAG NO: AAGACTTTGCAGAACCTTTAATTGGATGTGTTAAGTGTTTTTAATGAGTGTATGAAATGTAGA 1199 AAGATGTACAAGAAATAAATTAGGAGAGATTACTTTGTATTGTACTGCCATTCCTACTGTAT PTPN2 ADXCRPD.12103.C1_s_at CGGCCCTTGCGCCTTTCTAGCATAAAGTGGTGTGTCAGAGCCACTGTCTCCACAGAAAGCACC SEQ ID ACGTTTGTTTCATTTGACTTATTTGAACCCGTTTCTCCTGCCTTTGCCTTTTTAAATAAAAAT NO: AGCAAAAATTGATTCAAGTGAATCTATTAGAATTTTCTAAAATGGAGCCCATTTGTCTTTTCA 1509 GTCTTGCAAGTAAAGTCTTTAAAACAATTAAGCCTCCCAATGATTTAACCGTATT PTPN2 ADXCRPD.2533.C1_at CAGTATTACACAGTGGGAGGTCCAAATTGGATTAGACTTTGGCATTGAATTCCAAAGTATTGG SEQ ID TAAGTCTAGCACATACTATAAAGGCTTTGCTAAATTCTGGTGGGTACATTATTTTTAAAACCT NO: GTCTGTCTGTCGGTATCACACAGAGGTCACTTCTTGAGTAAAATAAGATGACCTTAAGAATTC 1523 ACATAATTCTTGAAGAAGAATATAAGTCACGATGCTTCCACATGAGGCCGCGTCACACCACCA TCGTTTGGAAATCCAGCACCTCAGCCGT PTPN7 ADXCRAG_NM_002832_s_at GGAGGAGCTGCTCCTTCCTTACAGCCTTGGGGATGGACTTGCCCACACCTCCACCTCCCCTGA SEQ ID GCCCTGTGAGAGGCACGACTGTCTATGCCAATGAGGCTCGGTGGGGGGCTCTCAAGTGCCTGA NO: TCCTGCCCTGGGCTCAGAGCCAGCCCAGAGGGAAGCAACTGCACAGCCCCACAGGCCCTCCCT 1019 GGCACTGTCCCCCCAACCCCATCTCAGAGCTCAGAGGGTACAAGCTCCAGAACAGTAA PTPN7 ADXCRAD_BG388017_x_at TGAGCCCTGTGAGAGGCACGACTGTCTATGCCAATGAGGCTCGGTGGGGGGCTCTCAAGTGCC SEQ ID TGATCCTGCCCTGGGCTCAGAGCCAGCCCAGAGGGAAGCAACTGCACAGCCCCACAGGCCCTC NO: CTTGGGCACTGTCCCCCCAGACCCATCTCAGAGCTCAGAGGGTACAAGCTCCAGAACAGTAAG 2705 CAAGTGGGAAAATAAAGACTTCTTGGATGACTGAAGACAAAAAA PTPRC ADXCRAD_BM795677_s_at GTTTTCAATTTTGCATGCTCGATTATTCCCTGTACAATATTTAAAATTTATTGCTTGATACTT SEQ ID TTGACAACAAATTAGGTTTTGTACAATTGAACTTAAATAAATGTCATTAAAATAAATAAATGC NO: AATATGTATTAATATTCATTGTATAAAAATAGAAGAATACAAACATATTTGTTAAATATTTAC 1020 ATATGAAATTTAATATAGCTATTTTTATGGAATTTTTCATTGATATGAAAAATATGATATTGC ATATGCATAGTTCCCATGTTAAATC PTPRC ADXCRPD.12778.C1_at TAAGCCTGTATGTACTTTGTTGTCAGCAACTTCTAGGTCTTTCTATCTTTGCCACTTCTAGTT SEQ ID CTTCCTCTCTTACATATGTTACATATGCACATATGCATGTGCACAATCACTGGTATGAATGCA NO: AAGTCAAAAGAGAAAATATAAAAACAGCTTATTTTCCAAACTGCTTTACTAAGCCCTCTGCAA 1632 AGTTTTAGTTCTTTCTGCTCAGATTTATGAAATAAAAACTTCCTGTGTTAAATGTCAAAAAAG TCCAGCAAGATAGCCTTGATT PTPRC ADXCRPD.12952.C1_at TTCATCTGAATCATGCTCACTCTCTTTACTCATTTCCAGCTCATGTTTAAGTGGCACTCTGTT SEQ ID ATAGTCATATGGGATGACATTAGAATTCCTGTTTTTACTTTTATTTTCTTCTTGATTTCCAAT NO: GTGCTGTGTCCTCCAGCTCCTATATGAAGGAAGTCTCTGGAATTCAGCCTCTAGTGGAGACGG 1675 CTCACTGGGTGGATCCCTTTTCTTCATGTTATGTAGATATGGATGTAATTCAGACAAATTCAC TTCTGTTTCTCCAAACTGATTGTATTCCACCAAAGCCTGAGT PTPRC ADXCRPDRC.12952.C1_at TGCTGCTCAGGACCACTGATGGACGAAGACTTC SEQ ID NO: 1998 PTPRC ADXCRPDRC.12952.C1_s_at GAGACTTCCTTCATATAGGAGCTGGAGGACACAGCACATTGGAAATCAAGAAGAAAATAAAAG SEQ ID TAAAAACAGGAATTCTAATGTCATCCCATATGACTATAACAGAGTGCCACTTAAACATGAGCT NO: GGAAATGAGTAAAGAGAGTGAGCATGATTCAGATGAATCCTCTGATGATGACAGTGATTCAGA 1999 GGAACCAAGCAAATACATCAATGCATCTTTTATAATGAGCTACTGGAAACCTGAAGTGATGAT TGCTGCTCAG PTPRC ADXCRAD_BX436427_s_at AGGGTCAAACTACATAAATGCCAGCKATATTGATGGTTTCAAAGAACMMAGGAAATACATTGC SEQ ID TGCACAAGGTCCCAGGGATGARACTGTTGATGATTTCTGGAGGTGATTTTGGKGAWCWKAAAG NO: CCTTWGTTATTKTCATGGTCACTCGATGTKAAGAAGGAAACAGGAACAAGTGTGCAGAATACT 2535 GGCCGTCAATGGAAGAGGGCACTCGGGCTTTTG PTPRC ADXCRAD_BG546180_s_at GAAAATAGGTATACAGTGGATTAATTAAATGCAGCGAACCAATATTTGTAGAAGGGTTATATT SEQ ID TTACTACTGTGGAAAAATATTTAAGATAGTTTTGCCAGAACAGTTTGTACAGACGTATGCTTA NO: TTTTAAAATTTTATCTCTTATTCAGTAAAAAACAACTTCTTTGTAATCGTTATGTGTGTATAT 2636 PTPRC ADXCRAD_BC031525_at ATTACTGTACTTAGTTGGCTATGCTGGCATGTCATTATGGGTAAAAGTTTGATGGATTTATTT SEQ ID GTGAGTTATTTGGTTATGAAAATCTAGAGATTGAAGTTTTTCATTAGAAAATAACACACATAA NO: CAAGTCTATGATCATTTTGCATTTCTGTAATCACAGAATAGTTCTGCAATATTTCATGTATAT 2797 TGGAATTGAAGTTCAATTGAATTTTATCTGTATTTAGTAAAAATTAACTTTAGCTTTGATACT AATGAATAAAGCTGGGTTT PTPRCAP ADXCRPD.5068.C1at CCCAACCACAGGCATCAGGCAACCATTTGAAATAAAAC SEQ ID NO: 1645 PTPRCAP ADXCRPD.5068.C1_x_at ACCACAGGCATCAGGCAACCATTTGAAATAAAACTCCTTCAGCCTG SEQ ID NO: 1646 PTPRE ADXCRAG_BC050062_s_at ACAGTAGAATAACCACGGGCAATTAAACTTTAAATTTTCTGAGCAGCATTTTGGTATTTAAAC SEQ ID ATTTCTTGTAAAAAGCTGAGACAGTTTGTAAGAAAAGAATCCTTAAAATCTAGATTTATACCA NO: TTTTTTAAAGTCCCACCTTTCAATGTTTAATAAAACAAAAAGAAATCCTTAATCTAAAAGCTA 970 AATTATTTTTGAATGGAAATACTACTGAGACCATTGACACTGGATAACAGTAATGATCCCATT ACCA PTPRE ADXCRAG_NM_006504_at AACCTTTACTTTGACTACCAGCCTGTGTTTTT SEQ ID NO: 1035 PTPRE ADXCRAD_BM725213_s_at TTTAAATGAGCCTGACACCTGTGTTTCAGCATTTGGAGACATCCCCATGTTATTCTTTTAAGT SEQ ID GTATAATTACTGATACTTTTTTGTTTGTTTGTTTAACTAAGTTGTGTTTAACTTATGTGCAGT NO: CTTTATAATGTATGTATGTTATTACAGTTTCAACTATCATATTTTCTTTGATTACATTTATAA 1036 TTTGATCTTGCTCTGATTATAATGCCAGTGAATGTTGCTGAACTCTTTGTATATGCAAATTGC AAGATTTAAACCATTCTGATGCAAGGATAAACCT RAC2 ADXCRAG_BC001485_s_at AATTTTCTACGCCTCTGGGGATATCTGCTCAGCCAATGGAAAATCTGGGTTCAACCAGCCCCT SEQ ID GCCATTTCTTAAGACTTTCTGCTCCACTCACAGGATCCTGAGCTGCACTTACCTGTGAGAGTC NO: TTCAAACTTTTAAACCTTGCCAGTCAGGACTTTTGCTATTGCAA 914 RAC2 ADXCRAD_CV027630_s_at AAACCGTGTTCGACGAGGCCATCCGGGCCGTGCTGTGCCCTCAGCCCACGCGGCAGCAGAAGC SEQ ID GCGCCTGCAGCCTCC NO: 2461 RAP1B ADXCRIH.1784.C1_s_at ACCTGAGAGAACAGATTCTTCGAGTTAAAGACACTGATGATGTTCCAATGATTCTTGTTGGTA SEQ ID ATAAGTGTGACTTGGAAGATGAAAGAGTTGTAGGGAAGGAACAAGGTCAAAATCTAGCAAGAC NO: AATGGAACAACTGTGCATTCTTAGAATCTTCTGCAAAATCAAAAATAAATGTTAATGAGATCT 1133 TTTATGACCTAGTGCGGCAAATTAACAGAAAAACTCCAGTGCCCGGGAAGGCTCGCAAAAGTC ATCATGTCAGCTGCTTAATATACTAAATGCATTGTAGCTCTGA RAP1B ADXCRIH.1078.C2_at GCTCTTTGGACTTTCTTTTATTATGCTAAAATAGTGGTGCTTTTAGGATTTACATTATTGTAC SEQ ID TCTCCAATACAAAGTATGGGGCATGTTAAAGTATACAGTACACCATTTTCATACATGTACAAC NO: ATTGGTGGATGAAGAATGTCTCTTAGCAGTAATACTGGAGGTAGCCCTCGTGCCGA 1303 RAP1B ADXCRIH.1078.C2_x_at AGCGAAGTTATCTGGAGTAGTCTATATAGGAGCTCTTTGGACTTTCTTTTATTATGCTAAAAT SEQ ID AGTGGTGCTTTTAGGATTTACATTATTGTACTCTCCAATACAAAGTATGGGGCATGTTAAAGT NO: ATACAGTACACCATTTTCATACATGTACAACATTGGTGGATGAAGAATGTCTCTTAGCAGTAA 1304 TACTGGAGGTAGCCCTCGTGCCGA RAP1B ADXCRIHRC.1078.C2_s_at ATATGTAATTGGTCACAAGGCCTAATTTGCAGTAACTATTGCTGTTTTATTTAACAATGCCTT SEQ ID GTTGCTTTGTATGCATTAATGTTTGGATGTAAAGATTGTGTGTCTATCCAACAGGGAGCCACA NO: GTATTTAAATTGACCAACCTAATGTTACAACTACTTTGAGGTGGCCAAATGTAAACTAAAAGC 1336 CTTAATTAAAGTGGTGCAATTTTGTATAACTTAGCATCAGTAGTTCAATAAATTTGGATTGCC ATGCAAGGGCTTG RFTN1 ADXCRAG_BC032349_s_at ATCGGGACTGGCTGGCGCCCTTGTTATGTGCTATTTTAATCAGTGTAACATTGGTCAAGTTGT SEQ ID TACCCATGTATGCTGTGTTTATCATGTGTATATCGTCCAGAAAGTATTAAGGCTTTAGGTAGA NO: TGCAACTGGCGAACCTTGGAGAGGGAATGCTGATTGTCTTGACCAAACCCACAGC 954 RFTN1 RDCR221_B10_at GCAAGTATGCCGTTCTGGTGAAGATCATGGGGCAAAGTGAATTTTGATTCTTGAGTTTCTGTG SEQ ID GGCCAGAAATCCAGGTGGGCTGAACTGGGTCGTCTGCTGCTTAGGGTCTCAAAACACTGAAAT NO: GGGATGTCAGCAGAGCTGTGTGCCTTATTAGAGGTTTTGGTGGGGAAGAATCCACTTCCAAGC 1346 TCACTTAGGTTGTTGGCCTTGTGGTTGCAGGTCTGAGGTCCTTGTTTTCTTGCAGGCAGTTAT CCAGGAGCTGGTCCTTGCTCCT RFTN1 ADXCRPD.13500.C1_at GAAAACTGAGTCTTACACAATGAAGTGCTACATCTTGGACATTAGACTGCTTGTTCCTCCATT SEQ ID AGAGCAGCCGACTGACCAGTAAATCAATCCAAGAGTTCAATAAGGAAAGATACAAGTGAGGCT NO: AGCAAACGCCCAAGAGACTGAAAATACAGTGGGGTGGTAATACCTCAAGAAACCAAACCTCAT 1659 GTGAACTAGGGAAGCAAGCAGTGCTCCAGGTGGTCTACTGACAACAAGACCGGAGGATGCACA AAGAAGATAAAACGCACGTGGCGACTCACCAG RFX5 ADXCRAG_AL050135_s_at AAGCAGTAAACCAACTAATATTTATTGAAGACCTACTTTGTCCTCTACATAGGGTAGCTTCTG SEQ ID TCAGGGAATCTTGGTTCTTCCCAAGAAACACTGATTTTCTTTCAGGGAGACTTCATGTGTTCA NO: TTTATTTCCACCACAGCAGATTTTAAGAAATTATAATATGTAATATTTGATATCTATAAAGAG 886 TATATCTAACGTGAATAAATTATGAAGCATACTAATGAGTACCTATGACCCATAACACATATA CATT RFX5 ADXCRPD.5339.C1_s_at AGGACCATTTAAGTCTGGGCCACTTAATGGCTGCCAGCATTCCTAAGATTACACTTTTCCCCA SEQ ID TTTATGTCCAATCAGAAAAAGAAGGCATCTTTGTACCAGAAATCTCAGCAAAAGCCCTAATAT NO: TCACACTGATTAGGCCTGGGTCACATGTCCACCCTGACCAATCACTGTGGCCAGGAGGATGAT 1694 ACATGCTA RFX5 ADXCRAD_BI256444_at CAAGGGATTCTCATGGTTCATGTGACTTAGAAAGTCCATAGGTAAGTGCTGGCTCCAGGTGAA SEQ ID GCACTTGAACCAGTAGTTCAGTATGTCTCTAAATACCGGACTGACTTTTTTCTCACTGTTGCA NO: TCTTCTGTAGGACCACTTAAGTCTGGCCACTTAATGGTTGCACATTCCTAGATTACCTTTTCC 2403 CA RFX5 ADXCRAD_BI256444_x_at TTAAAACTACCAAGGGATTCTCATGGTTCATGTGACTTAGAAAGTCCATAGGTAAGTGCTGGC SEQ ID TCCAGGTGAAGCACTTGAACCAGTAGTTCAGTATGTCTCTAAATACCGGACTGACTTTTTTCT NO: CACTGTTGCATCTTCTGTAGGACCACTTAAGTCTGGCCACTTAATGGTTGCACATTCCTAGAT 2404 TACCTTTTCCCA RHOG ADXCRIH.1986.C1_s_at ATCACACCGCAGCAGGGCCAGGCACTGGCCAAGCAGATCCACGCTGTGCGCTACCTCGAATGC SEQ ID TCAGCCCTGCAACAGGATGGTGTCAAGGAAGTGTTCGCCGAGGCTGTCCGGGCTGTGCTCAAC NO: CCCACGCCGATCAAGCGTGGGCGGTCCTGCATCCTTCTTGTGACCCTGGCACTTGGCTTGGAG 1225 GCTGCC RHOH ADXCRAD_BM919440_at ATCCCTTGGGGGAACTGGTGATGAATAATTCCATCTTTGGATTAAAAAAGTGAAAATAGTCTC SEQ ID CCATAATTTTTGGGACCAATGAAGTTGAGT NO: 2435 RHOH ADXCRAD_BM919440_s_at GGATACAGTTATTGATGAGGCTTGGCCACTGGATGTTTTCACTAACTACACTCTACAAGTGAA SEQ ID CTCCTTGCCCAGGCCAGTTAGAAAATCCCT NO: 2436 SAMSN1 ADXCRAD_CD522843_s_at GAGGATTCGCTGTTGAAACAAGTTGTCCAAGCAATGTTATATTCATTTTTATACTTATTGGGA SEQ ID AAGTGTGAGTTAATATTGGACACATTTTATCCTGATCCACAGTGGAGTTTTAGTAATTATATT NO: TTGTTGATTTCTTCATTTTGTTTTCTGGTATAAAAGTAGAGATAATGTGTAGTCACTTCTGAT 872 TTAGTGAAACCAATTGTAATAATTGTGGAAATGTTTTGTCTTTAAGTGTAAATATTTTAAAAT TTGACATACCCTAATGTTAAT SAMSN1 RDCR115_B08_at ATTGCTAAAATATGTGTCTATTAAATCAATGTACTCAATGTACATCTCTGTGGAAATCTTCTC SEQ ID TCTGTACCTAACCTCTGATATGTTTTCTGAAGGATGAGG NO: 1344 SAMSN1 RDCR115_B08_s_at GATGGAGAGAATGCCCACCCATATAGAAACAGTGACCCTGTGATTGGGGACCCACACAGAGAA SEQ ID AGTGTCCCTCAAAGCCAGTGACTCCATGGATAGTCTCTACAGTGGACAGAGCTCATCAAGTGG NO: CATAACAAGCTGTTCAGATGGTACCAGTAACCGGGACAGCTTTCGACTGGATGACGATGGCCC 1345 CTATTC SAMSN1 ADXCRPD.2125.C1_at CCCAAACCGCCTCCATTATTTGAAGTTTTACTTTGTTCTCCACTTCCATTTGTGGGATCTCCT SEQ ID TCATGTGCCTCAGTTGAATCATCTGGTTTTGATAAAGAATTATTCCGAAAACGATCGAAATTC NO: CCAAAACTGCTGCTTCGCTTTGGTTTTTGATGTTTCTCCTTCTCTGAAACATTGGATGGCTTT 1429 CTCTTGAGCATTTTGAATTCTGACTACTCCTAGTGAGTGCACTTTCTGCTGT SAMSN1 ADXCRAD_BU198472_s_at TTATCACAGAGCCAAGTGACTGAACACGCATTCCCAACTATATATCTACAGATGCATTCCATT SEQ ID TTAACTCTTCTTGAGCTAAAACGTCAAATAGGAGAG NO: 2323 SAMSN1 ADXCRAD_BQ082118_x_at AGTTATTTTACTCATGCTGTGTTTTTTAATATAAGCTTTACAAAAAAAGATGCATTCCCTTCC SEQ ID TGTTCACACTCTTACCATGTTTTTGTTCTTCCTTAAGAATGATTGTGTGTGTGTGTGTGTGTG NO: TGTGTGTGTGTAAGTGTAACATCATGGGTTTTCTTTCTTCACTTGTAAAGTTTTATCTAGAAA 2448 TACTTTTACAGGTTATGTTGAGGTACACAAAGATAATGTTCTAAGATTGTGTATTGGATT SEC31B ADXCRAG_NM_015490_s_at TGCCCTTGACTCCACCTATGTTGGAGCCTTAGCCCAAGGCCATTCCTTCTGTGATGATAAAGC SEQ ID CCAGTTCTGGAATTGGAGCCATATTAAGGAATGATTCTCTTCCAGCGCTGCTCCTCAAGGGTT NO: GGGGGTCCTTCTCCCTCGCAGCCACCACATGTCTCAGGGCTACCTTCTCCGATTGGATTTGCA 1045 TTTGTGGCACTGTCTTTGATGCAGTGATGTACTTAA SEC31B ADXCRPD.17780.C1_at AAAGCAGGCACTCAGCTGGTTTTGGAGCCAAGCCTACAGCATCACATACCTGGCAGCAAGGAA SEQ ID AAGAGTCGGGAAAAAGAAACAGAATCTGTTGCAGAAGTCCCCCTCTTCTGCAGGGAGGAGTTA NO: TGTAACAGCAGAAGTGGCCTCCTAGCAAGAGAGGCTGCCTGGTTTAGACCAGCAGCTTATGAG 1424 CGATGATGAGGACAGCCTTCAGGATAGGCATGAAGCTGGACACCTCGCTGAAGCTGATACA SEC31B ADXCRPDRC.17780.C1_at CTGCTGTGACCATCATGTGGTCTTTGTTCTCCTTCTGTCGTCTTCTCGGATCCTCTAGATC SEQ ID NO: 1929 SEC31B ADXCRPDRC.17780.C1_s_at AAACCAGCTGAGTGCCTGCTTTTTACTCCTTTTATGTCTGGCCTTCTAGGATCTGGTCCAAGA SEQ ID CACTCTCAGGGCCTGGGAGGCAGGGCATAGAAATCAGTTCTTCACTCTCCCTAATACTACACT NO: CTGTAAGGACCTGGGGCAGGATATCTTCTCCCCCCAGGGGATCTTCTATTTAAGTGGCTTTTG 1930 AGAGGGTGAACAGGATTGTTACTTTTAAGCCTACCTCTG SELPLG ADXCRAG_AY331789_at GTCTCTCATTAACAGCCAGTAGCTTATTGGTGATCCTAGATGCAGCCTGCAACCTTTTGTACA SEQ ID ACTCACAGAAGCACTGATTTGCTGTCAAATGGTGGAAAAGTTCAAGCTGCCAAACTTTTTCTT NO: AAAGGACCAAACAGTGAATACTGTAGGCCTTAACTGTTGCAACACCATAGCCTCTGTTGCAAC 906 AACTCAACTCTGTCCTTGTAGTACA SELPLG ADXCRAG_U02297_s_at GGGCAAGTGGAGCCACCTCTTTCCTCCCTCCGCGGATGAAGCCCAGCCACATTTCAGCCGAGG SEQ ID TCCAAGGCAGGAGGCCATTTACTTGAGACAGATTCTCTCCTTTTTCCTGTCCCCCATCTTCTC NO: TGGGTCCCTCTAACATCTCCCATGGCTCTCCCCGCTTCTCCTGGTCACTGGAGTCTCCTCCCC 1059 ATGTA SELPLG ADXCRSS.Hs#S2980215_s_at GCACACTCAGTGACTATAAGCTTCCTGAGAGCAGGGCTGTTCTGAAGAGATTTGAGTTTTCTC SEQ ID CTGGCCATGGAGAGTGTAATTAAGTAGCCCTGGGCCCTTGAAGACTTATAGTGCAGGTTGACT NO: GAAAGAACTAAATCAGCCAGTCTTTGCGGAGAGGTTGTCATGCAAACGAAGTGCTAAGGGTCT 2144 TGCATGCATCCCTTCATTTTATCCTCACAATAGACTGTGAAGTAGGCACCGCCATCCCTGTTG TGCATTGTGCAGGC SELPLG ADXCRAD_BI818193_s_at GGGCAGCTTGGGTCTTCTTGGGCACCTCTCTGGGAAAACCCAGGGTGAGGTTCAGCCTGTGAG SEQ ID GGCTGGGATGGGTTTCGTGGGCCCAAGGGCAGACCTTTCTTTGGGACTGTGTGGACCAAGGAG NO: CTTCCATCTAGTGACAAGTGACCCCCAGCTATCGCCTCTAGCCTTCCCCTGTTGGCCACTTTC 2500 CAGGGTGGACTCTGTCTTGTTCACTGCAGTATCCCAACTGCAG SERPINA1 ADXCRIH.3253.C1_s_at TACTGGAACCTATGATCTGAAGAGCGTCCTGGGTCAACTGGGCATCACTAAGGTCTTCAGCAA SEQ ID TGGGGCTGACCTCTCTCGGGGTCACAGAGGAGGCACCTCTGAAGCTCTCCAAGGCTGTGCATA NO: AGGCTGTGCTGACCATCGA 1259 SLA ADXCRPD.8133.C1_at AGGCTAAGAAGTCCTTTGGGCTAATGTTTAGGGTCACGAAGTTCCTTTAAAAAGAGAGGAAAG SEQ ID CATACCAAAAGTCCCTATGGATTAGTTAAAGTAGTTCCATTCAGGGCACCCATCTGCAAACCC NO: AGACCTTCTGCCAGGACACAGCTTTTGTTTCCTCTCCCTCTCAGGCTTGCCATACAGAAGTTC 1807 TCTCCAATGACCTTGGAGTGTAACTGTCTGGACAGGTCCAGTTCCTTGGAGAGCAGTCCTGGT GCCCCTTCCTGTGAGAGTGGGCTTGTCCC SLA ADXCRAD_AL548133_s_at AAAGGAACCAGCCAACGTATGAGAAATGAATGTAACACTGTGGACATTGACTTCCCGCATAAG SEQ ID GCAGGGTGACCCCCTGAACTCCAGATGTCTGCACAGTATCTTATGTGTTGTTTTCCGTTGTGA NO: CGAATGTGATTGGAAC 1866 SLA ADXCRPDRC.8133.C1_at CATTAAGTCCTCTGTAAGGTGTCAGGCAAGCCNNNNNNNNNNNNNNNNTGGGTAAGTCCTAAC SEQ ID CCCCCACAAAGGTGTTCCCAGTGACTACCT NO: 2026 SLA ADXCRAD_BX436824_s_at ACCAAAGCCATATGGGTGGAAGTCAGTTGGCCTCCCTGGTTCTGCAGAGGGCCAGAAGAATGA SEQ ID GAGAGAGGAAGACTGCTGGCAGGGAAATCGAGGAGGCGAGACTAGAACTGCACCAGCTTCCCT NO: GATGTCTGCAGCCATGGCTTTGCAGCGCAGACAGAGCTTCTCTGGGATGCTGGGATTCTTGCC 2027 TGTATGAATGCATCAAGTATTCATTTATTGCCCGAATAGGCATTGCATTAAGTC SLC16A3 ADXCRPD.4071.C1_at GGACCTGTCCCGTAGAGCATGTGCCAGCAGGATGGAGGAGATCCAGGCTGTGTCGCTGTAGCC SEQ ID GATCCCAAACTCCTGTATGAGCTCCTTGAAGAAGACACTGACGGCCTTGGGGAAGGCGTAGGA NO: GAAGCCAGTGATGACGAAACAGCCGAAGAGCACTGGACCAGC 1575 SLC16A3 ADXCRPDRC.4071.C1_at ATATTCGCGCCCCATGGTAGCCAAACACCGAGCACAACCACTCCCCCTCTTGTCGCGGCTCGT SEQ ID ACCACATACCCGTCTCTTACGCGCGCCACAAGCATGAGGNGCTCACGCCCATCTTTTTTGTCC NO: ACCTCCGTGATGAAACCCCGCGCCCACTGACTTTATTAGCGCCCTACGCACTACACATAATTG 1967 CCGCCAGCCTGATACCCACACCGCGTCCTNATAGATCACTCGTCGCCCTGTAGCG SLC19A1 ADXCRAG_U17566_s_at GAAGTACGTCCCAGCGGCCTCAGGGTCTAAGGAGCGCTAGTGCCTTGCCCACAGGTGCGGGAC SEQ ID CATCTGATGTGATGTGAATACTCTTCCCACATACATTAAACACACTTA NO: 1064 SLC19A1 ADXCRPD.7962.C1_s_at GCCGCGGGCTTCGTGAAGATCCGCTGGGCGCGCTGGTCCAAGCTGCTCATCGCGGGCGTCACG SEQ ID GCCACGCAGGCGGGGNCTGGTCTTCCTTCTGGCGCACACGCGCCACCCGAGCAGCATCTGGCT NO: GTGCTATGCGGCCTTCGTGCTGTTCCGCGGCTCCTACCAGTTCCTCGTGCCCATCGCCACCTT 1389 TCAGATTGCATCTTCTCTGTCTAAAGAGCTCTGTGCCCTGGTCTTCGGGGTCAACACGTTCTT TGCCACCATCGTCAAGACCATCATCACTTTCATTGTCTCGGACGTGC SP110 ADXCRIH.149.C1_s_at ATCCTCAGTGAAGTGCATTCGGAATGAGGATGGAACTTGGTTAACACCAAATGAATTTGAAGT SEQ ID CGAAGGAA NO: 1202 SP110 ADXCRIH.149.C1_x_at ATATACGTTGTGAAAGGACGACCCTAGGAGAGCTGCTGAAGAGTGGACCTTTGCTCTGTCCTC SEQ ID CAAGAATAAATCTCCAGAGAGAGTTTAAATAGCAAGTGAATTTCTACTACC NO: 1203 SP110 ADXCRPD.2201.C1_s_at AAGCACTTCAGTGACCAATGACAAGTTAACATCCAAAATGAATGCGGAAGAAGACTCAGAAGA SEQ ID GATGCCCAGCCTCCTCACTAGCACTGTGCAAGTGGCCAGTGACAACCTGATCCCCCAAATAAG NO: AGATAAAGAAGACCCTCAAGAGATGCCCCACTCTCCCTTGGGCTCTATGCCAGAGATAAGAGA 1456 T SP110 ADXCRAD_NM_080424_s_at GACTTTGGCCAGGTAGGACTTGACTTAGAGGCAGAATTTGAAAAAGATCTCAAAGACGTGCTC SEQ ID GGTTTTCATGAAGCCAATGACGGCGGTTTCTGGACTCTTCCTTGACCCTGTTCTGTAAAGACT NO: GAAGCATCCCCACCTCAGGATTCAGCTGATGGGACCCTGGCTTGGACTGTTGATTGCCAGTGA 2760 GTCTGGGATGTAATTGGCTGCCCTCAGGACCCAAACCCAGACACTTCATAGGATTATCACACC CTCCATCTTTATT SP140 ADXCRAG_U36500_s_at TCCCATACAGGCTCTTACCTCTTCTCCTGAGGGCTGCTCCAGACAACATTTATTACCCAGAAG SEQ ID ACCTTTTGTCTGAAAACCAGCCAAGCTTTATTCAGGACACACTTCTTGCCTTCACTTTCCCAC NO: TTCCGTGGCCACCTCCATGCAGAAGCCCTAAGCCCACATTCTTTCGATAGCTCACGGTGGTGC 1066 ATGAGTGTCCATCATCTGACTCTT SP140 ADXCRPD.734.C1_at AGCACATACTGGTACCCCTGAGAGGAGCTGCCTGTGAAAGCTATAAAGACAGAAAANNNNNNN SEQ ID NNNNNNNNNNNCCTTTTCCCGACCCATGGGGTTTAAATTTCCAAACTTGTGGGGAAGGCAAGG NO: CTGATGAAGAACTTGACCTTTTGGAACAAAAGAAAATTGAAAGCGGCATTTCTTGGCAAAGGG 1605 TTT SP140 ADXCRPD.734.C1_x_at TATCATCCAGTGCAGTCCTGGGTCAACTTGTTTCTCCAACAAAGACTGGAGAAGTCACGAAGA SEQ ID GAGCCTAGCACATACTGGTACCCCTGAGAGGAGCTGCCTGTGAAAGCTATAAAGACAGAAAAN NO: NNNNNNNNNNNNNNNNNCCTTTTCCCGACCCATGGGGTTTAAATTTCCAAACTTGTGGGGAAG 1606 GCAAGGCTGATGAAGAACTTGACCTTTTGGAACAAAAGAAAATTGAAAGCGGCATTTCTTGGC AAAGGGTTT SP140 ADXCRAD_BG757090_at TGCGCGGACAACGAGGTACAGGACAGGGCCCAGAGCCAAAGCTGGTACCCTGACCCAAGATTC SEQ ID CCGGCCCACAACGGGGATAAACCGGCACGGACCCCATAAAAGAGGAACCAGATAACATCACCA NO: GAAAAGCCAGGGTAAACCGTGACTACAGAAACGCCGAAGAACAAACAGCACGCACAAGCGCGG 2707 CAACA SP140 ADXCRAD_BG757090_x_at TGCGCGGACAACGAGGTACAGGACAGGGCCCAGAGCCAAAGCTGGTACCCTGACCCAAGATTC SEQ ID CCGGCCCACAACGGGGATAAACCGGCACGGACCCCATAAAAGAGGAACCAGATAACATCACCA NO: GAAAAGCCAGGGTAAACCGTGACTACAGAAACGCCGAAGAACAAACAGCACGCACAAGCGCGG 2708 CAACA STAT3 ADXCRAG_AY572796_at GAGAGGAGGTGGTTGCCTTAATCCCCCCCGCCAACCCCCTTATGTTAGCCACCAGCCCGGAGG SEQ ID TAAGGGGTGCCTGGAGGAGCAGGAGGTCAATAGTCCAACGGCAGAAAGGTGTCAGAGTGGAGG NO: CCTCCCTCCCCGGCCCCCTCCTACCCCCCAGAGCGGCCTCGTCCTGTCTGGGGTCAGATAAGC 911 CACCTAAGCGGGGTGGGGGGTAGATACTCCCACCGCACCAAGGCCTCCCCTTCCACAGTTGGC TCCTTTATCACTTTCCCTTCAGTT STAT3 ADXCRIH.2963.C1_s_at GTTCAGGGCTTCTCTGGAGCAGATATTGTCAAGTTCATGGCCTTAGGTAGCATGTATCTGGTC SEQ ID TTAACTCTGATTGTAGCAAAAGTTCTGAGAGGAGCTGAGCCCTGTTGTGGCCCATTAAAGAAC NO: AGGGTCCTCAGCCCTGCCCGCTTCCTGTCCACTGCCCCTCCCCATCCCCAGCCCAGCCGAGGG 1233 AATCCCGTGGGTTGCTTACCTACCTATAAGTGGTTTATAAGCTGCTGTCCTGGCCACTGCATT CAATTCCAATGTGTACTTCATAGTGT STAT3 ADXCRPD.13006.C1_s_at TAATGGTGAAGGTGCTGAACCCTCAGCAGGAGGGCAGTTTGAGTCCCTCACCTTTGACATGGA SEQ ID GTTGACCTCGGAGTGCGCTACCTCCCCCATGTGAGGAGCTGAGAACGGAAGCTGCAGAAAGAT NO: ACGACTGAGGCGCCTACCTGCATTCTGCCACCCCTCACACAGCCAAACCCCAGATCATCTGAA 1566 ACTACTAACTTTGT STAT3 ADXCRPD.15731.C1_s_at GGATAACGTCATTAGCAGAATCTCAACTTCAGACCCGTCAACAAATTAAGAAACTGGAGGAGT SEQ ID TGCAGCAAAAAGTTTCCTACAAAGGGGACCCCATTGTACAGCACCGGCCGATGCTGGAGGAGA NO: GAATCGTGGAGCTGTTTAGAAACTTAATGAAAAGGTAATTTAGCATCCTTGTCCCTTTCCCTC 1783 ATCTAAAAAATACCTAAAAGACTCACGTGGTAGAGTGAGAGGCGGGCTGACTTCTGGTCA STAT3 ADXCRPD.7602.C1_s_at GGTGTGGTTGCACTGAAGTTAACAAGATTCAAACCGTCGCCCAAGTTGGTATTTCCATGTTTG SEQ ID GTACACATCACTCTGTGCCATATCAGGTCGTTGTTAAGTGTGGTGACAAAATCAGTGGTTAGT NO: CATTTTTTTAATTAAAAATGTGTATAGTGTGTACCTGCTGGTCTTACTGTATGTGCAACTAAA 1827 GGTTTACATAGTCTGTGTATGGGTTGTAAATTTTTGGCTGGCTGTGCTGATAAAGCATTGGGC TT STAT3 ADXCRSS.Hs#S1751591_s_at TCAGGATGGTACGTGGTTGCCAGCAGAGAGCTGCTCCTCAAGTGAAGGAGGTAGAATCAAAGC SEQ ID CAATAGGAAAGAGCCTCAGATGCTTATATATGTACCGTGGGGATTCAGAGTGAAAGCAGTCAT NO: TGGACTAGGGGTGGGGTTAGGGAGAGCCTGTCTGACAGACACAAGAAAGGGATGGATACGCCA 2108 CCCAGAGAAAAAAGCATTTTAGGCAAGAACAAAT STAT3 ADXCRAD_BX409785_x_at AGAAACTCAGTTACAGCCTCCTTGGTGCTTTAGCATTCAGCTCCCTTCAGCTGGNATTTATAT SEQ ID AATCCTGAAACGGCTTTAGTCCA NO: 2644 STAT3 ADXCRAD_AI682905_x_at AAGAGATGAGGGTTCACTTTGTTGCCCAGGCTGGTCTTGAACTCCTGGGCTCAAGCAACCCTC SEQ ID TTGCCTCCATCTCCCAAAGTGCTGGGATTATAGGCATCGGCCACTGCACCCAGCTACACACAC NO: TTTTTCACCACCACTCCAGCAAAGTTCTGAACAGAAAATTACCTTTAAAGAGTTTCTCTGTGT 2872 CATAAAAATACTTGGCAAAAGGTATTAATAAAATCTGACATACAAGGGATGTAATGACCCTTC AAAATCACTATTCTTATTGCTCGGAAGCGATCAATACATTG TACC3 ADXCRAD_BX107802_s_at CAGGCGGAAGCGTTGGCCCTCCAGGCCAGCCTGAGGAAGGAGCAGATGCGCATCCAGTCGCTG SEQ ID GAGAAGACAGTGGAGCAGAAGACTAAAGAGAACGAGGAGCTGACCAGGATCTGCGACGACCTC NO: ATCTCCAAGATGGAGAAGATCTGACCTCCACGGAGCCGCTGTCCCCGCCCCCCTGCTCCCGTC 1785 TGTCTGTCCTGTCTGATTCTCTTAGGTGTCATGTTCTTT TAF1A ADXCRPD.7472.C1_s_at CTACATTAAAACATTCTTAGGCCATTGCTTTCTAACTTTTATAGCATCTACAGAAAATTTCAA SEQ ID TAATGTACAGTACACTGAGATAAACAGAGAAAGTTGGCTCCAGCTGCCATCTCCATGTATGTA NO: TCATCCACGCTATCCCCTGCTGCCCGGATGAGACTGAGGAGAGAGGATCAGAAGTCTTGTGCA 1798 ACCCTGGTTGGAATACTCTGCACTGATATTTTTTGAAAATCAACTTTATTGAAATTTAGTTTT CAGAGAGTAAACACACTTAT TAF1A ADXCRAD_CN293583_at AACCACCTTGCGTGGGTTCAAGAAGAGTGGAACTCCAGGAAAAACTGGTGGCCAGGCTTTCAT SEQ ID TTCAGCTACTTTTGGGCAAAAAGTGATTGGAAGGAAGATACAGCTTTGGCCTGTGAGAAAGCT NO: TTTGTGGCTGGTTTACTGTTAGGAAAAGGTTGTAGATATTTCCGGTATATTTTAAAGCAAGAT 2453 CACCAAATCTTAGGGAAGAAAATTAAGCGGATGAAGAGATCTGTGAAAAAATACAGTATTGTA AATCCAAGACTCTGATACTGAATTTTAG TAP1 ADXCRPD.4854.C2_s_at CAGCTGCCTCCAGGATGAGTTACTTGAAATTTGCCTTGAGTGTGTTACCTCCTTTCCAAGCTC SEQ ID CTCGTGATAATGCAGACTTCCTGGAGTACAAACACAGGATTTGTAATTCCTTACTGTAACGGA NO: GTTTAGAGCCAGGGCTGATGCTTTGGTGTGGCCAGCACTCTGAAACTGAGAAATGTTCAGAAT 2282 GTACGGAAAGATGATCAGCTATTTTCAACATAACTGAAGGCATATGCTGGCCCATAA TGFB1 ADXCRPD.3499.C1_at SEQ ID GGAAAGGCCGGTTCATGCCATGAATGGTGGCCAGGTCACCTCGGCGGCCGGTAGTGAACCCGT NO: TGATGTCCACTTGCAGTGTGTTATCCCTGCTGTCACAGGAGCAGTGGGCGCTAAGGCGAAAGC 1580 CCTCAATTTCCCCTCCACGGCTCAACCACTGCCGCACAACTCCGGTGACATCAAAAGATAACC ACTCTGGCGAGTCGCTGGGTGCCAGCAGCCGGTTGCTGAGGTATCGCCAGGAATTGTTGCTGT ATTTCTGGTACAGCTCCACGTGCTGCTCCACTTTTAACTTGA TGFB1 ADXCRAD_BU782064_s_at TCCACGGAGAAGAACTGCTGCGTGCGGCAGCTGTACATTGACTTCCGCAAGGACCTCGGCTGG SEQ ID AAGTGGATCCACGAGCCCAAGGGCTACCATGCCAACTTCTGCCTCGGGCCCTGCCCCTACATT NO: TGGAGCCTGGACACGCAGTACAGCAAGGTCCTGGCCCTGTACAACCAGCATAACCCGGGCGCC 1970 TCGGCGGCGCCGTGCTGCGTGCCGCAGGCGCTGGAGCCGCTGCCCATCGTGTACTACGTGGGC CGCAAGCCCAAGGTGGAGCAGCTGTCCAACATGATCGTG TGFB1 ADXCRAD_NM_000660_at TTAAGGGAGGAGTTCCTGCCCACCAGGAACCTGCTTTAGTGGGGGATAGTGAAGAAGACAATA SEQ ID AAAGATAGTAGTTCAGGCCAGGCGGGGTGCTCACGCCTGTAATCCTAGCACTTTTGGGAGGCA NO: GAGATGGGAGGATACTTGAATCCAGGCATTTGAGAC 2802 TGFB1 ADXCRAD_NM_000660_x_at TTAAGGGAGGAGTTCCTGCCCACCAGGAACCTGCTTTAGTGGGGGATAGTGAAGAAGACAATA SEQ ID AAAGATAGTAGTTCAGGCCAGGCGGGGTGCTCACGCCTGTAATCCTAGCACTTTTGGGAGGCA NO: GAGATGGGAGGATACTTGAATCCAGGCATTTGAGACCAGCCTGGGTAACATAGTGAGACCCTA 2803 TCTCTACAAAACACTTTTAAAAAATGTACACCTGTGGTCCCA TIAM1 ADXCRAG_U16296_at TCCAGGAAACTGAACACTGAGATCTGACTGCGTCACCTGCCCCGTAGAGAATGTGTGTAGATA SEQ ID CTTCCTGCCCTAACTCTGCCCACCCTCCTGTACCGTCGACAAGAATGTCCCCTTAGGTCGCGC NO: TCTTGCACACACGGTTTTGGCAGCTGACTTGGTTCTGAAGCCATGTAGCCACCCAACTTTGTC 1062 ATTTTCAACAACATCAGAAAGAATTGATCAGAATCCCAAATAAAACCCAAAAGTGTCTAATGT ATTCA TIAM1 ADXCRAD_BM808025_at ATATCATCTCCGGTTCGATCGCGTCCAGATGGAAAACGGAAGCAGAGGCTTCTAATCGTCGCA SEQ ID TTTACTGGCTCCAGTGCAACACATCCATCTGAAAACACTCGGAAGTCTGGTGCTTGGAGAGGG NO: TGCCATTGTCTCTTGTACATAAGGTCATGACGTGTCTATGTCAAAAGTTCTTATATATTTCTT 2666 TTATAAGCTGAAAGAAGGTCTATTTTTATGTTTTTAGGTCTATGAATGGAACGTTGTAAATGC TTGTC TM6SF1 ADXCRAD_BG570659_at AATATTACTTCATGTTCCTCCTTTCTAAATTACTAACTTTTGTTATACTGGTACTGATATTTT SEQ ID GTCCCATTTCACTCTCTTCTCATACGTGAGTACTTAAGAATATGTACATTCTTGCTCTGCACT NO: GTATGTGTGAGCTATATGGTATTGTGTAAATTTTTTTTGGAAGGACAATGGAAATTCTTGAGA 2587 AACAGTTTGTTTAAACGAAATATATTTCAAACTCATTTGTGAATAAATTGATCATCCATCTCA ATATGTTTGA TM6SF1 ADXCRAD_BG285017_at GAATTTTTTAATATGCACAGGCCATATTCTCTTTTGAATAGTTTCATTTCATGCTCACTACTG SEQ ID TTGGCACTAAATGTAATTTTTTACACTTATAATTATTTTATATGTCAAACAATATTGAGATGG NO: ATGATCAAGTTTATTCACCAAATGATTTGAATATATTTCTTTAAACAAACTGTTTCTCAAGAA 2745 TTCCATTTTCCTTCAAAAAAATTTACACAATATCATATAGCTCACACATACAGGCAGAGCCAG AATGTCTATTCTAAGTACCACGTTGTGGA TPK1 ADXCRAD_CD511474_at TAAAATGGAAGCGGTTGGACTGATGGTGTCTGAGGTTCTTTCCCACACTGAAATTCTAAATAT SEQ ID TGACACTTAGCAGTCATAGGGCTGATAATACACACAGTTACTGACTTAGCCTAAACAACCTGG NO: TGCATCGAAATGTAATCACCCTTTCTTTTGTAAAAGAGACCCATCTTCTATCTTCCTTTCCCA 2381 CCTTTTCTCTGTTTTTATGAAAACCCAACTGTTGGACATTCCAAACCATTGGATTTGA TPK1 ADXCRAD_CD511474_s_at ATTGACACTTAGCAGTCATAGGGCTGATAATACACACAGTTACTGACTTAGCCTAAACAACCT SEQ ID GGTGCATCGAAATGTA NO: 2382 TPK1 ADXCRAD_CD511474_x_at CATCCCAGTCTGATATTCACCTAAGTTTCCGGACCCTTTTCCTTAGCTGTAAAATGGAAGCGG SEQ ID TTGGACTGATGGTGTCTGAGGTTCTTTCCCACACTGAAATTCTAAATATTGACACTTAGCAGT NO: CATAGGGCTGATAATACACACAGTTACTGACTTAGCCTAAACAACCTGGTGCATCGAAATGTA 2383 ATCACCCTTTCTTTTGTAAAAGAGACCCATCTTCTATCTTCCTTTCCCACCTTTTCTCTGTTT TTATGAAAACCCAACTGTTGGACATTCCAAACCATTGGATTTG TPK1 ADXCRAD_CR745173_s_at TGGCCCGCGTGATTGTGGCATTTAAGGAGCAGTGGCCCATGTGACTGTGGCATTTTCGGCACT SEQ ID TTTCATTACTTTCTGCTTGACCGGAAGTTGAGGCTTAGCTATGTTTCCATCTTCAGTTTCTGA NO: AGACTAGTTATATATTCCTTACTAGAAATATATTCATAATATATAAAAGAAATATATCTGTGA 2592 TTTTAAAATTTTGCTACCAAAGAATGCATGTTCTGTGTGCCCTGAAAATGTTAC TRIM14 ADXCRAG_NM_033219_s_at SEQ ID TGGACTACGAGGCCGGCGTCCTCGCCTTCTACGACGTGACGGGCGGCATGAGCCACCTGCATA NO: CCTTCCGCGCCACGTTCCAGGAGCCGCTCTACCCGGCCCTGCGGCTCTGGGAGGGGGCCATCA 922 GCATCCCCCGGCTGCCCTAGGGGCCAGGACCGGCGTGACAGCCTCCAGA TRIM14 ADXCRPDRC.2569.C2_at GCAGCAGCAGACTTGTTTAGGGCCTGTTTGAAACTAGCCTAGGAGAGGAAACCTTCAAAGCAC SEQ ID GGTAGGCGTGATGGGTCGGGGAAAGCTGGGGCAGGGAGAGGGCCCTAAGAAGCAGGCAGTAAG NO: GGGACCAGCCACGCTGATCTAGGTAGATTAGGCGAGACTGGGCAGCTGCGGCGACCTGGAGGC 2053 TGTCACGCCGGTCCT TRIM14 ADXCRPD.2569.C1_s_at CATTCCCAAGGGAGCTTGCACGGTACTGACCGAGTGCTGAGACTACTGGTATTCCCAGCTGCC SEQ ID ATGTGGCAGCAGCAGGAGCTACTAGAATATTCTCAGCACAGGAATGAGGCTTCCTTGGTTTCC NO: ATGTCTGTAAGGGTTACTGATCACTTACCTTCTTCTCTT 2276 TRIM14 ADXCRAD_BX389413_at TGGTCTCACTGGGAGTTCATGGTGCTTCAGTCCCTAGCACCCAGTGATACCCCCACAGGTAGC SEQ ID CCTAAGCATCCTGAAACATCATCCGC NO: 2407 TRIM14 ADXCRAD_BI222503_at CACTTAACCCCTCAGCTATGAAAAGGCTTCCAGGAGTTTCCATGACATAACAAAACAACAATA SEQ ID CAAGCGCCTCACCTTAGCATTCAAGGCTTGTCTAGTCTGCCCAACAATTACTTATCCTCACCT NO: AGCTCCTACCAGTCTTCTTAGAGACTCTCCAGTCAGAACATGTGTCGCATAGTTCCACTCCAC 2740 ACCTCTCTGCTGACAGCACATTCATGCAGACAAGTCTTTCCACTGTCTCAGACTTCCGCAGGC TTACCTGCGCAGGCAAGTCTAACCAA TRIM22 ADXCRPD.1317.C1_at GACACCCCATATTCATCACAAAATTAAAGCAAGAAGTCCATAGTAATTTATTTGCTAATAGTG SEQ ID GATTTTTAATGCTCAGAGTTTCTGAGGTCAAATTTTATCTTTTCACTTACAAGCTCTATGATC NO: TTAAATAATTTACTTAATGTATTTTGGTGTATTTTCCTCAAATTAATATTGGTGTTCAAGACT 1393 ATATCTAATTCCTCTGATCACTTTGAGAAACAAACTTTTATTAAATGTAAGGCACTTTTCTAT GAATTT TRIM22 ADXCRPD.1317.C1_x_at GACACCCCATATTCATCACAAAATTAAAGCAAGAAGTCCATAGTAATTTATTTGCTAATAGTG SEQ ID GATTTTTAATGCTCAGAGTTTCTGAGGTCAAATTTTATCTTTTCACTTACAAGCTCTATGATC NO: TTAAATAATTTACTTAATGTATTTTGGTGTATTTTCCTCAAATTAATATTGGTGTTCAAGACT 1394 ATATCTAATTCCTCTGATCACTTTGAGAAACAAACTTTTATTAAATGTAAGGCACTTTTCTAT GAAT TRIM22 ADXCRPD.2309.C1_at ACAAGTTTCTCTGGGATGTCGCTTTTCTCGACCTGCTTATCCGTATTTCAATCCTTGGAACTG SEQ ID CCTAGTCCCCATGACTGTGTGCCCACCGAGCTCCTGAGTGTTCTCATTCCTTTACCCACTTCT NO: GCATAGTAGCCCTTGTGCTGAGACTCAGATTCTGCACCTGAGTTCATCTCTACTGAGACCATC 1474 TCTTCCTTTCTTTTCCCTTCTTTTACTTAGAATGCCTTTGAATTCATTTGCCTAGGGCTTCCA TAGCCAAGCATCATA TUBA1B ADXCRIH.69.C1_at GATCATGTCTTTTCCATGTGTACCTGTAATATTTTTCCATCATATCTCAAAGTAAAGTCATTA SEQ ID ACATCCTCGTGC NO: 1293 TUBA1B ADXCRIH.69.C1_x_at TTTTGGCCCTGCAGCATGTCATGCTCCCAGAATTTCAGCTTCAGCTTAACTGACAGACGTTAA SEQ ID AGCTTTCTGGTTAGATTGTTTTCACTTGGTGATCATGTCTTTTCCATGTGTACCTGTAATATT NO: TTTCCATCATATCTCAAAGTAAAGTCATTAACATCCTCGTGC 1294 UBE2L6 ADXCRPD.250.C1_at TGCCCTTAACCCGATTTGGCCATTCCCCTCTCTCCCCCGTACTATACACCCCCGCCCCGCCTT SEQ ID CCTTCCCGCCTTTGTGCGCCTGTCCGATCATANTTTCCGCCCATGGTCCACGTTCTCCGCCGC NO: GTAACCTATATCCTGGATTCTCTTCCCGCCCCGCGTGTGCTACCCCCTTATTGCCATTTTCCC 1893 GTTACGCGGAGTTCGCCCGAGGCCCGGGGCTTTGTCGCCGCGTACTTTAGGCCCCGCCCCGCC TAAGTTCCGCCTTCATTATACCGCGCTGTG UCK2 ADXCRPD.10643.C1_at AAGATTAGATTCCTGCCTCGGGCCAGGTGAAAGGAAGGCAGGAAAGAGATTCTGTTTCCTGAC SEQ ID CCAACATTATCACAAAAGACTGTAACAAGGGCTGTGGGAGTTATGGACCAGGAACCTGGTTGA NO: AAACCATTATAAATCATAACACCACAAGGACCTATATTTTGCTTTTTAGGACATTGTAGTAGG 1461 TGGGTAGTTTTCATCCTCTTGCTTTTTAAAATCTATCTTGCCCAGAAGTTTATTGGGCATTTC TATGGAAACACAACACCTCTCTTAAAT UCK2 ADXCRPD.9879.C1_s_at GCAGGCCGCATTGACCCGTCTCCATCGGACCCCAGCCCCTATCTCCAAGAGACAGAGGAGGGG SEQ ID TCAGGAGGCACTGCTCATCTGTACATACTGTTTCCTATGACATTACTGTATTTAAGAAAACAC NO: CATGGAGATGAAATGCCTTTGANNNNNNNNNNNNNNNNGTACTTTGGAACGACAAAATGAAAC 1541 A UCK2 ADXCRPD.5097.C1_s_at ACTGGCATTCCAGGTCAGCTTGGCTGTGGTCTTAGAGGCAGGGAGTGCCTACCCAGTCCTGCC SEQ ID TCAGGAGCAGGGTGAGTAGCTAAATACAGACTTAGGCTTTTTTTCCCCCCTTTTAAGATGCTT NO: GCTCCTCTCCCTTTTCTTTTTACCACCCTACCTTTATTGTTAGTGGTTACAAAGTGACCACAT 1651 ATTATGTACTTTGCTGTAA UCK2 ADXCRPD.14415.C1_s_at TAGCGGCAAGTCTTCCGTGTGTGCTAAGATCGTGCAGCTCCTGGGGCAGAATGAGGTGGACTA SEQ ID TCGCCAGAAGCAGGTGGTCATCCTGAGCCAGGATAGCTTCTACCGTGTCCTTACCTCGGAGCA NO: GAAGGCCAAAGCCCGGAAGGGCCAGTTCAACTTTGACCACCCGGATGCCTTTGACAATGAACT 1702 CATTCTCAAAACAC UCK2 ADXCRPD.15116.C1_at CCCCTCTGCCAGACAGTGGGTTGAACACACATGTACACCTGAGGAGGAGGGTCTGACGAGGGC SEQ ID TGCCTCAGAGTCAGAGGCAGCAGGACTAGCTCTGTATGTTCGACCTCATGTCTGGCCCATCTT NO: GAGTCCCAGGCTCATACAAAATCACCTGTGTTCAGATACAGATTCAACTCAGTATTTAATGAG 1715 CCAAGCACTACTTGAAGCATCTTGACAGTCCTTCTCTTCACATAAGCCCCGACAATCACATCT GCAAGGTACGTATCAAGTCCCTACGTTCCGAGACA UCK2 ADXCRPD.14599.C1_at TTAAACTCCACCAAGACCCAGCAAGAAGAGCCTCATGGCAGGCTAGGACTGAGTTCTTCCCAG SEQ ID AAGACAGGTCTAAAACACAAGCTTTTCCACCTTAACAATGGATGTCTCCTGACCCCTTCCTCC NO: AGAAATCAAATGGCCAATCTGATGCCCACTTCAGCTTCTGTCATCCCTCTGTAGTCAGACAAG 1728 GAGGGCTCGCTCAGCTTGCATTTCCTTCCTGAAGAGTATTCACTACCTCTCTTGTTCAAACAC TATGTATCACTCAAT UCK2 ADXCRPDRC.5097.C1_at GCAAAGTACATAATATGTGGTCACTTTGTAACCACTAACAATAAAGGTAGGGTGGTAAAAAGA SEQ ID AAAGGGAGAGGAGCAAGCATCTTAAAAGGGGGGAAAAAAAGCCTAAGTCTGTATTTAGCTACT NO: CACCCTGCTCCTGAGGCAGGACTGGGTAGGCACTCCCTGCCTCTAAGACCACAGCCAAGCTGA 1983 CCTGGAATGCCAGTCCCCGGTATGAGGAAGGCAGC UCK2 ADXCRPDRC.5097.C1_x_at GCCTTTTTGTCTGTCTTTATTTACAGCAAAGTACATAATATGTGGTCACTTTGTAACCACTAA SEQ ID CAATAAAGGTAGGGTGGTAAAAAGAAAAGGGAGAGGAGCAAGCATCTTAAAAGGGGGGAAAAA NO: AAGCCTAAGTCTGTATTTAGCTACTCACCCTGCTCCTGAGGCAGGACTGGGTAGGCACTCCCT 1984 GCCTCTAAGACCACAGCCAAGCTGACCTGGAATGCCAGTCCCCGGTATGAGGAAGGCAGCAGA ACGCCCAGAGACA USP7 ADXCRAG_AY376241_s_at CCCCAAAGAGGAGTCGCTACACTTACCTTGAAAAGGCCATTAAAATCCATAACTGATTTCCAA SEQ ID GCTGGTGTGTTCAAGGCGAGGACGGTGTGTGGGTGGCCCCTTAACAGCCTAGAACTTTGGTGC NO: ACGTGCCCTCTAGCCGAAGTCTTCAGCAAGAGGATTCGCTGCTGGTGTTAATTTTATTTTATT 908 GAGGCTGTTCAGTTTGGCTTCTCTGTATCTATTGACTGCCCTTTTTGAG USP7 ADXCRPD.11382.C1_at GAAATACTTGCCTAAGTTTCCCTGATGCTTTCTCCCCAAGCTCCACGGCCTTTTTACATTCTT SEQ ID CTAACAGGTCCCGGACACACCCATGCTTGTCTGGATATAGTGTTATTTCCTAAGTAATGAAAA NO: GATAAAATAAGTGCTTTCAAGAAAGCATAAAAGGTCTGCTACCACAAAGGAAGAGAGGAGAAA 1480 GTTGCATCATTGTTCTCAACTGTCCCCAGCTGGCCCCCATGTTCTTGCTCTCATTCCNCACCC CAACTCCCTCATCTGTGAATTCACTC USP7 ADXCRPD.16454.C1_at GTCTGTCTGGATAAAAGCGTGGCATCACCATAATCTTCCATGGCAGATTTCGCACAAAACACG SEQ ID GAGGGCTAAGGACCGACTCACTCAGTCTGCTGAAGCGCTCCACAGTGAACTGAAAGGCTGCCT NO: CGGAGCGCCAACTGGTGTCATCCTCCATGTCCTCCTCCGCGGTGTTGTGTCCATCACTCAGGG 1794 CCACATTCCCATTGATCACAGGGTTCTGAGTAATTCTTGGTGGCTCATCATGTATCTCCCG USP7 ADXCRPD.949.C1_s_at CTGCAAGTGAATTTCACTGATGTTGATATTCATTGTGTGTAGTTTTATTTCGGTCCCAGCCCC SEQ ID GTTTCCTTTTATTTTGGAGCTAATGCCAGCTGCGTGTCTAGTTTTGAGTGCAGTAAAATAGAA NO: TCAGCAAATCACTCTTATTTTTCATCCTTTTCCGGTATTTTTTGGGTTGTTTCTGTGGGAGCA 1919 GTGTACACCAACTCTTCCTGTATATTGCCTT USP7 ADXCRPDRC.11382.C1_at AAGTATTTCTTGAGCCCAATTGTGGACGTTCAGTTAGGGGTGGCAGTTAACGCTGACCTCTGC SEQ ID AGTTGCGTTGGTGGAAATCACCCAGCTGGGATCCATGCGCGTCATTCCCAGACTCAGTGGGGT NO: GTGCCTCCATTGCAAAGACAGTTGCACAGAAGCTCAACACAGACCCATTGTTGCTCCAGTTTT 1940 TCAAGTCTCAGGGGTAACCCTCAAGCCGCTGTGGTGCAGAGGGTTATGCGTGTTTCACAATTA AGCCGCGACA USP7 ADXCRPDRC.16454.C1_at GGGATTTCCAATATTATGGGCATGGAGTAAATGGC SEQ ID NO: 2022 USP7 ADXCRPDRC.16454.C1_s_at GACTGAGTGAGTCGGTCCTTAGCCCTCCGTGTTTTGTGCGAAATCTGCCATGGAAGATTATGG SEQ ID TGATGCCACGCTTTTATCCAGACAGACCACACCAAAAAAGCGTAGGGATTCTTTCTCCAGTGC NO: AATGCTGAATCTGATTCCACGTCATGGTCTTGCGAATGCACAAGCAGTGCTGAAGATAATAAC 2023 TTACAGAGATGATGAAAAGTCGTTCAGTCGTCGTATTAGTCATTTGTTCTTCCA USP7 ADXCRSS.Hs#S2990382_at GATAAATCTTCGTGAAGTGGCAGAAAATATGAAAGCCAGCCAATTGGAATCTTGCTTATTCTG SEQ ID ATCTGTTATCTCAGGGGTTAGATTCGCGTGCTGAAGTGGTCTACGTAACTTCCATAGCGATTG NO: GGAGGTGTTCTCTGGTGGGGTAGCAGTTCTGTGTTATGACATCACACATGGAATTCACGGGGA 2141 GGAAAGCTGGGTATAGGCATTAAGTGCCCAGTAGAGCAGGT USP7 ADXCRAD_BU956106_at CGCTCTTTCCCTTCATTGTGGGGCATTGTTCGGGCCCTTC SEQ ID NO: 2368 USP7 ADXCRAD_CA439064_at GAAGGGCCTCGTGACACATCAGGTCACATCTCCAGTCACCTTATTTGTACACAGTTCTCTCCT SEQ ID GGAAAACCTTTCATTTCTTAAGAGTAAATGTGACTAGTTAGAGGCTAAAAAAAAAAAAAAAAA NO: GAAACAAGAGACCCTGCCCCCGCAAAACGGAATTAGAAGGAAAAGTACATCTCAGTGAAACCT 2489 TGTTACAAATGCCAAGGTTTCCCAGGCCTGTTTCCAGGGAGAGTAGAATCTTCCTCCACTTCC ACGTAACTCACTGAATTATA USP7 ADXCRAD_CA437914_at TGTGTACCTTGGAGTGACTTCCTTTCTCAACTTCCACTGCAGTGTGTGTGCCTTCTGCTCTGA SEQ ID GAGCTGCCTTGTGACCCGTGTGATAGAAAGCAGGGAGTGAGGGTCCCCGCGGACCTGGCCCTT NO: CCCTCCTTCCTCCCCCAGAAAGAGGAGTTAGAGCAGGGGTGCGAGAGCCGTTCGCTGTGGGTT 2597 TGTCTTTGAACAAACATTAAGGTGTCTTGTTTTTGTTCTGGGCTGGGGGTTGGCTGTAGTCTT AGGTAACTGAAAGTTCCTACTCTCCCTTAAG USP7 ADXCRAD_AI972599_at TTGGGAACCAAATGGCTCCAAAAGCCATTTGTCCTCCAAGCGACTACAGGGCAAAGTAGTGAG SEQ ID AATCATGCCCATCTCTCTGAAATAAACAATCAATTCAGGGGCTTCTTTCTACAGCCCAAATGT NO: TGGCTAGATGGAACAGAAGTGACTCAATCTGTCAAATACAAAATCAGGAGTCACCCCTTCCAG 2811 TTTCAGTTCATCGTTCAAATGGAATCATATCCTTCCTCTGTTTGGCTTTTCTATGGGAACTGC GC WDR59 ADXCRPD.15558.C1_s_at CAGTGTTACCCTGTAAGGTGTTAGCCTTAAACCACCGAGCAGCGTTCTCTTGATGCCAGTGCA SEQ ID GAGACCAGAGTCAGATGCCCGAGGACAGTGGGTAGGAATTTCATCAACAAATGGACCTATGGC NO: ATCATGGCTTTAGAAGCTGGTACATTTACTGAGCTGATGGACAGTGGCCTTCTAAAATATGAC 1764 ACTTAAATTGTAAATATGCACTGTACTTAAGGATTCTTAAGATGTATTTTTTTGTTATTTCTC CTCCAGCTGCTATCCCTTGGCTAATAAA WDR59 ADXCRAD_AA393120_at CCCCTAGAAATCTCCTGGAAGAGAGGAAATCAGATCAACTGGGGCTGCCTCAGACCTTGCAGC SEQ ID AGGAATTCTCCCTGATCAATGTGCAAATCCGGAATGTCAATGTGGAGATGGATGCGGCAGACA NO: GGAGCTGCACAGTGTCTGTGCACTGCAGCAACCATCGTGTCAAGATGCTGGTGAAGTTCCCTG 2596 CACAGT WHSC1 ADXCRAG_AF071593_s_at CCTGTTGAGGTGTGAAATGCCCCGTCAGAAATTAAATACAAACTTAAATGTGCCTATTGGTGT SEQ ID CTAAACTTCATACAATGTAAGGTCAGATTCCTTTTAGGAATACTGGGTGCTGTCACCAGGTTT NO: GATAGTTAGACT 851 WHSC1 ADXCRAG_AF071594_s_at ACTGTGGCTAGTTGTCTGTCCGGTGGCTGGGAGGGGGTGTGGTGGGAAAAAGTCGGAATCTCT SEQ ID GCAATCTGTGTCATGGACTGTACTATTGTAAGGTCTATATTCTGTATGTGGGTCCCAGACCCT NO: GATCAGGAAATGAGCCTCATGTGTGTCGTTAACATTTATATATTTCCATTCAAAATATGTATT 852 CAGTGTTTATTTCCTCAAAACAGACTTTGTTAATGTAGGAAATCTCTCCAAGTGGAAACGTGC TAACTTTTTCTGTA WHSC1 ADXCRAG_AF083391_at TTTATTCCTTTAGTAGAGCAAATTCTTATTTTTTTCGCCTTCACTGGTAACAGCTTTTGTGGG SEQ ID AGC NO: 854 WHSC1 ADXCRAG_AF083391_s_at ACCAGTCAAGTTGGATTTGAACCCAGCTGCTCTGTACTGCACTTAGAATGATGTAATATTCCA SEQ ID GGATGCTGCTGCAGGTGGCGTATCATCGTACACACTCAGTGACATTTCTATCACAATCATTTT NO: ATGGAAGATGTGTGATAATCTGTTTTTACTGGTA 855 WHSC1 ADXCRPD.10380.C1_at CCATATGCCAATTAACTTTAACCTAAAAAAATAGAGTGGGAGGGAACCTTGACATTCGGAGAA SEQ ID ATTCNAGTGTGCCGGTAACGCTGAGGAGTGAGGCTGTTTGTCCAGGAACGCTGAGCTGGGCTC NO: AGACGGTCATCAGTGCAGACGCAGCGGACGCTGCTGAGGATGGCTCAGTGGTGGGGAGGCGCT 1396 CCCTCCCGAGGAGGCCTGTACGTCTGTGTCCTGGCGGCTCGAGCTGGGTCCTCCGGGCCAGTT CATGCTCG WHSC1 ADXCRPD.1426.C1_at GCGTCTCGTCAGATATCTCTACTGAAATGTGGTGCGTGTCGCGGGGNCGAGNAGACACTCTTC SEQ ID TTTCGACTNACTCTACCTGTGACTATATATGTGTGNNCTCGTTCCGCCTNACTACGCATTTAG NO: CACACTATCCCTCGTTAGTCTCTCGTCTCCCCATAATACGAGTACCACGCGCTCGTCTGTCAT 1416 ATCAGATAGGATACATAGTCTGGGGCCTCTCGTATGATTCATTTCGCTCGCCCGCCACGAGTA ACAATCTTGCGTTCCCACCCTCCTTCGTCCCTCTGTCGTTGGAAGGCC WHSC1 ADXCRPDRC.10380.C1_s_at TCCCAAGGGTCGCTAGAAACTCGTCTTCGCGTTGCCCCCTTTCTGGCTCTCAGCGCCGTCGCC SEQ ID ACTCGGGAGAGGCTGGGTGAGGCCCGTGTGAGGACTGACCCTGGATTCCTCGAAACTGCCATT NO: GTGATCATTACTCTGCTCTTTGGAAATGGCTG 1922 WHSC1 ADXCRAD_BM712589_s_at GTCAGAAGTTGATAGGTTGTTAAATACATTTATATAATACATTAAATATGTGAAATTAATACA SEQ ID CCTTCCTACATTTTGAAGGTGATGCATAGATCCCATAGTGTGCATCATGTTCCTTATATGAAA NO: ACGTTTAAATTACTGGGTCTTTTCCATTAAACTACTTTTGTATGGCTTAGATAAATCTTCCAT 2351 TAGTGTTCATTTTTATAGAATTATGCTGTTAAAACTACTTTAGGTGAACAAATAAACTTGTCT ATTATATATTAACGCGACTGAACTACAG WHSC1 ADXCRAD_BM755805_s_at CAGGTGTCCGCATTTTTGCATGGTAAGGAAAAGGCTTACTTGCCCTTCAGCTCATAAAAGCAG SEQ ID AAGGTGTGCTATTCACAGTACCATGCGAGTAGCCCACAGTTAATTCCCGGCAGATTCTTTGGC NO: TGTGTTTTATCTTTAATGAACGTTTCTGACTAATATTTTGTTGTAAACCATTAAGTAATGTAA 2352 CGCATGTAAGATGCTTAGGGTGCCTGGCCAGGACTCCGTGGTTTCCTGTTGTGACAGTAATAA T WHSC1 ADXCRAD_CN390223_s_at TGGTGCTGTGTGACCGCAAGTTCTGCACCAAGGCCTACCACCTGTCCTGCCTGGGCCTTGGCA SEQ ID AGCGGCCCTTCGGGAAGTGGGAATGTCCTTGGCATCATTGTGACGTGTGTGGCAAACCTTCGA NO: CTTCATTTTGCCACCTCTGCCCCAATTCGTTCTGTAAGGAGCACCAGGACGGGACAGCCTTCA 2483 GCTGCACCCCGGACGGGCGGTCCTACTGCTGTGAGCATGACTTAGGGGCGGCATCGGTCAGAA GCACCAA WHSC1 ADXCRAD_CN390208_s_at CCCGTAGTTTTTTCTCCTCATGGATTTGAATGAAATGCCAATAACACGTCCACTTTCAACGTG SEQ ID TAGTTTACGCGGAGCACTTTCGAGGCCTGGCCGGGTTGGGCCTACTTCTCACCTGGGCCTATC NO: TTCTGAACTCGCTAGGTTCTTATCAACATT 2484 WHSC1 ADXCRAD_BF970701_at GTGTTGGACACTGTGTATGAGTATTTTGTTTCAAAACTTTAACGCCTTTTCTTACGTTAAAAA SEQ ID CAAAAAGGGGGGCGCTAAAGTTCTCCCGAGCGCCCAGTAGCGGTACCCGCTTTCCGTCCACAG NO: GGGCCCCATGAGAGCCGGAAATAAGCAAAGACAGGCGAGTTTAACAGCGGCGCGGGAACCCGC 2485 GCCGTCGGGACCTGGGAGGAACCACTCCGGGGGACATGGACACCCAGAAGAAGCCGGAAAAAA AGGGAGCTAAACGCACTCGCGAGTGCTGTAAAACACACAAG ZAP70 ADXCRAG_BC053878_at SEQ ID ACACCGGCCTTGCATTGCCTGCCTGGCCCCCTGTCCTCTCTGGCTGGGGAGCAGGGAGGTCCG NO: GGAGGGTGCGGCTGTGCAGCCTGTCCTGGGCTGGTGGCTCCCGGAGGGCCCTGAGCTGAGGGC 973 ATTGCTTACACGGATGCCTTCCCCTGGGCCCTGACATTGGAGCCTGGGCATCCTCAGGTGGTC AGGCGTAGATCACCAGAATAAACCCAGCTTCC ZAP70 ADXCRAG_BC053878_x_at GAGGGTGCGGCTGTGCAGCCTGTCCTGGGCTGGTGGCTCCCGGAGGGCCCTGAGCTGAGGGCA SEQ ID TTGCTTACACGGATGCCTTCCCCTGGGCCCTGACATTGGAGCCTGGGCATCCTCAGGTGGTCA NO: GGCGTAGATCACCAGAATAAACCCAGCTTCC 974 ZAP70 ADXCRAD_AW950959_at TGAGCCCTGCTTGGGTTGTTCCACACACAGTTGGCCTGT SEQ ID NO: 2321 ZAP70 ADXCRAD_AW950959_s_at GCACTCATGAGTGACTGCTGGATCTACAAGTGGGAGGATCGCCCCGACTTCCTGACCGTGGAG SEQ ID CAGCGCATGCGAGCCTGTTACTACAGCCTGGCCAGCA NO: 2322

TABLE 10 Genes and corresponding Almac probesets predicting resistance to irinotecan. There can be multiple Almac IDs/probesets associated with a given gene. Almac SEQ ID Gene Probe ID Probe Sequence NO ACTN1 ADXCRAG_BC011987_s_at GGAAAGATTAACTATTTGCACCGAAATGTCTTGTTTTGTTGCGACATAGGAAAATAACCAAGC SEQ ID ACAAAGTTATATTCCATCCTTTTTACTGATTTTTTTTTCTTCTATCTGTTCCATCTGCTGTAT NO: TCATTTCTCCAATCTCATGTCCATTTTGGTGTGGGAGTCGGGGTAGGGGGTACTCTTGTCAAA 934 AGGCACATTGGTGCATGTGTGTTTGCTAGCTCACTTGTCCATGAAAATATTT ACTN1 ADXCRSS.Hs#S3748482_at GGCACAGAGGAAACCCGCTGAGCCTGCTTCCTTAGTTCTGGCAGATGGGTCAGCCCCCACAGG SEQ ID ACTCAGGATTCAATTTAGCCCGGGGTTCTGGCTCCATCTCCCACAGTGCCGGTGCCAGTGTGC NO: TCCTAAGTACTGTTTGTGCAAACCTGGCTCTGACTGAGACAAGGAGCCTTAGGAGTAGTAGGG 2203 ACAGGAGACACAGCAAACTAGGGCTCAGA ACTN1 ADXCRAD_CX871590_s_at TCTCCTGCCTGGGTTCGGTTTCAGCTCCCAGCCTCCACCCGGGTGAGCTGGGGCCCACGTGGC SEQ ID ATCGATCCTCCCTGCCCGCGAAGTGACAGTTTACAAAATT NO: 2469 ACTN1 ADXCRAD_BM714793_at AAGAGAATTTATGTGGCTTCTCATTTTTAAATCCCCTCAGAGGTGTGACTAGTCTCTTTATCA SEQ ID GCACACACTTAAAAAATTTTTAATATTGTCTATTAAAAATAGGACAAACTTGGAGAGTATGGA NO: CAACTTTGATATTGCTTGGCACAGATGGTATTAAAAAA 2737 ACTN1 ADXCRAD_M95178_at GACGTCAGCCTGTACAGGCTCCCAGGGGTGGCGTCAAATGCTATTGAAATTGCGCTGAATCGT SEQ ID ATGCTTTTTCC NO: 2816 ACTN1 ADXCRAD_M95178_x_at GTGCGCCGTGCCCACAGATGTGAAATGAATGTAATCTAATAGAAGCCTAATCAGCCCACCATG SEQ ID TTCTCCACTGAAAAATCCTCTTTCTTTGGGGTTTTTCTTTCTTTCTTTTTTGATTTTGCACTG NO: GACGGTGACGTCAGCCTGTACAGGCTCCCAGGGGTGGCGTCAAATGCTATTGAAATTGCGCTG 2817 AATCGTATGCTTTTTCCTTTTGA ASAH1 ADXCRAG_U70063_at TAAACAGTCACTGGAAAGAGTGCCAGTCAGCAGTCATGCACGCTGATAAAAAA SEQ ID NO: 1074 ASAH1 ADXCRAG_U70063_s_at TCTTCAGATTGATAGGGAGTTTTAAAGAAATTTTAGTAGTTACTAAAATTATGTTACTGTATT SEQ ID TTTCAGAAATCAAACTGCTTATGAAAAGTACTAATAGAACTTGTTAACCTTTCTAACCTTCAC NO: GATTAACTGTGAAATGTACGTCATTTGTGCAAGACCGTTTGTCCACTTCATTTTGTATAATCA 1075 CAGTTGTGTTCCTGACACTCAATAAACAGT ASAH1 ADXCRSS.Hs#S1748600_at TTTTCCTTATTTTCAGACTACTGTACTGCCTATTAAAGTTGATTTCAGACATGCAAAAAAACC SEQ ID TGGAAGAAATGTTGCAGGGCTAGAAACATTCTTCTCTTCCTCATAGTTTACTTCTACCCATCT NO: ACATGATTTGATAGAAGTGCTCGCAGGAGGTGCTTCCTTAACTTCGGTGTATGTCATGACATC 2086 TGTCCTTTTCTTGAGGGCCAGAACAC ASAH1 ADXCRAD_BQ186493_s_at GATCAAGATACGGAAGAGCCCAGCACTCCACGATGCTCCATCATGCCCCTTTGCAGAAAATAC SEQ ID TGCCTCCTCCAGTAAACACTATTCTGATGTCACTATAGATAAGTTTTGCCTCTTCGTGAACTT NO: TGTATAAATAGAACTGAACAATATGAACTGTCCTGTGTGATTTCTTGTATTTCATTATGGGTG 2730 GTGTGCTATTGTATCAACAGGGTAT C19orf21 ADXCRIH.3146.C1_at AGGGTGGCACAGATCGCAGCACCTTGAGGGGCTGCGGGTCTGAGGGAGGAGACACTCAGCTCC SEQ ID TCCCTCTGAGAAGTCTCAAGCTGAGAGGAGAGACCTGCCCCTTTCCAACCCTGGGAAACCATC NO: CAGTCTGAGGGAGGAGGCCAAACTCCCAGTGCTGGGGGTCCCTGTGCAGCCCTCAAACCCTTC 1204 ACCTTGGTGCACCCAGCCACACCTGGTGGACACAAAGCTCTCACATCGATAGGATCCCATGAG GATGGTCCCCTTCCCTGCGAGAAA CCND1 ADXCRPD.3501.C1_s_at TCTGTCTGAACCACGCGGGGGCCTTGAGGGACGCTTTGTCTGTCGTGATGGGGCAAGGGCACA SEQ ID AGTCCTGGATGTTGTGTGTATCGAGAGGCCAAAGGCTGGTGGCAAGTGCACGGGGCACAGCGG NO: AGTCTGTCCTGTGACGCGCAAGTCTGAGGGTCTGGGCGGCG 1592 CCND1 ADXCRAD_BM551840_x_at TGAGGGACGCTTTGTCTGTCGTGATGGGGCAAGGGCACAAGTCCTGGATGTTGTGTGTATCGA SEQ ID GAGGCCAAAGGCTGGTGGCAAGTGCACGGNGCACAGCGGAGTCTGTCCTGTGACGCGCAAGTC NO: TGAGGGTCTGGGCGGCGGGCGGCTGGGTCTGTGCATTTCTGGTTGCACCGCGGCGCTTCCCAG 1593 CACCAACATGTAACCGGCATG CCND1 ADXCRPD.3980.C1_s_at GGAGGTGGACCTGGCTTGCACACCCACCGACGTGCGGGACGTGGACATCTGAGGGCGCCAGGC SEQ ID AGGCGGGCGCCACCGCCACCCGCAGCGAGGGCGGAGCCGGCCCCAGGTGCTCCCCTGACAGTC NO: CCTCCTCTCCGGAGCATTTTGATACCAGAAGGGAAAGCTTCATTCTCCTTGTTGTTGGTTGTT 1679 TTTTCCTTTGCTCTTTCCCCCTTCCATCTCTGACTTAAGCAAAAGA CCND1 ADXCRPD.13939.C1_at TTCACATTGTTTGCTGCTATGTGGAGGATCAGTGTTTTGTGTTACAATGTCATATACTGCCAT SEQ ID GTACTAGTTTTAGTTTTCTCTTAGAACATTGTATTACAGATGCCNNNNNNNNNNNNNNNNNNN NO: NNNNNATGTGATCAATTTTGACTTAATGTGATTACTGCTCTATTCCAAAAAGGTTGCTGTTTC 1727 ACAATACCTCATGCTTC CCND1 ADXCRPD.16054.C1_at ACCAAGTAGCTGTGGGTTGAACCTGGACGTGAGCTGGTTGCAGGGCCGTTGGGTAGAAAACCA SEQ ID GCATCTCATAAACAGGTCACTACAAAAATAGGAAGAGTATAAAAATAGAATATATTATGTCAC NO: TATTTCGTCTTCTCTTTATAGTAGCGTATCGTAGGAGTGGGACAAGGTGGCCTTTCCCGACAC 1752 TGCTACGCTGGTCTGTGCCCGACAAACCTCACCTGATGTTGTACCTGAGTACGTTACTAAATC CTCAAGACCTTACACACAGC CCND1 ADXCRPD.15960.C1_at TGCCCGACAAACCTCCACTGGATGGTTTGTCACTGGATGGTTTGTTGGGGTGGTGGTCACAGG SEQ ID CGCAAAGGACATGCACACGGCCACGCTACGCTACTGTAACCAAG NO: 1817 CCND1 ADXCRPDRC.16054.C1_at GTAGTGACCTGTTTATGAGATGCTGGTTTTCTACCCAACGGCCCTGCAACCAGCTCACGTCCA SEQ ID GGTTCAACCCACAGCTACTTGGTTTGTGTTCTTCTTCATATTCTAAAACCATTCCATTTCCAA NO: GCACTTTCAGTCCAATAGGTGTAGGAAATAGCGCTGTTTTTGTTGTGTGTGCAGGGAGGGCAG 2013 TTTTCTAATGGAATGGTTTGGGAATATCCATGTACTTGTTTGCAAGCAGGACTTTGAGGCAAG TG CCND1 ADXCRAD_BQ436873_at AAAAATAGTATTTGCATAACCCTGAACGGTGGGGGAAGAGGGGTGTGCTACANATGATAGAGG SEQ ID GATTTTATACCCCAATTATCAACTCCGTTTTTATATTAATG NO: 2640 CPNE3 ADXCRAG_AF077226_at CAAGCTATAGTTAATGCCTCCAGGCTGCCTATGTCCATCATAATTGTTGGAGTTGGAGGTGCT SEQ ID GACTTCAGCGCCATGGAGTTTCTGGATGGTGATGGTGGAAGTCTCCGCTCCCCATTGGGCGAA NO: GTGGCCATCAGAGATATTGTCCAGTTTGTGCCTTTCAGACAGTTCCAGAATGCTCCAAAAGAA 853 GCACTTGCTCAGTGTGTCTTGGCAGAGATTCCCCAGCAGGTGGTGGGCTACTTCAATACATAC AAACTCCTTCCTCCCAAGAACCCAGCCACGAAACAACAGAAG CPNE3 ADXCRIH.2935.C1_s_at AGAAAAATTTGAAGTCTGATCAGAGATTTACAACTGTTCATTATAGTGGTGCCTTAGGCAATC SEQ ID TTTCCAAAGTAAATTCAGGGCCCCATTGCTACTTATGCCATATTTGGACATACNNNNNNNNNN NO: NCTTCAATTTTGTAAACTTCCTGGAAAGCTG 1227 CPNE3 ADXCRAD_BP222406_at TGAAATTCAGAATTCCGTTTCCTTCTAACTAATGAAAAACTGCTTACTAAAAAAAAATTTTAT SEQ ID ACTTTCCTTGCTAAGGTCCCATATATTGATTTGTACAGATCCACTTAGTCATTTTCTCCTTTT NO: 2387 CPNE3 ADXCRAD_BP222406_x_at TGAAATTCAGAATTCCGTTTCCTTCTAACTAATGAAAAACTGCTTACTAAAAAAAAATTTTAT SEQ ID ACTTTCCTTGCTAAGGTCCCATATATTGATTTGTACAGATCCACTTAGTCATTTTCTCCTTTT NO: TTTAAGAACCATTTTCATCTGATTTTTAAACTCACGATACCAGTTATCTGTTAATCAAAATTG 2388 CATTTTACAATTTAATAATGTGATATTTCCTATGTCTACAGCAT CPNE3 ADXCRAD_CB153171_s_at AAGCTGTCTTCACTAAGTATCCCCTAGTCTCTATATATGTGGTTAGTAGTCATGGAAATGACA SEQ ID CATAAAGTACGCCAGAAGTTTGATGGAACGTGTTAGAAACTGTTTTGTGCTTTTATGGATGTC NO: ATACTTGACAATACATGTGTAAGTTACTAATATATGAATTGATGCTAAATATATCTTACATTT 2615 GA CTBP2 ADXCRAG_AL833398_s_at GTTACATGTTCTATTCATAGTCTTTTGTGAATCATTGCCTTTTTGTTTAAAAAGATGGCCTAT SEQ ID TTTGAGCCTTTGTATAGGTACATTCCTGTTTTTGTGACAAAAGAAAAACTTTAAAATTGTCCC NO: AAACAGAAAAATAATGGCTATCAGAAGTATGTTTTGTTTTAGTGTGAGTTACCGTTACTGTAT 899 TTGTTTATTGTAAAGGTGGACATTTAGCGTTCAGTGCAGTTTTCAATAA CTBP2 ADXCRIH.1931.C1_at GTGACTTGAGTTCCCTTAAGTCCTCTGGGGCTGGTGACCTC SEQ ID NO: 1216 CTBP2 ADXCRIH.1931.C1_s_at ACGGAAGCGCTGAAAGACTAGGATGTGATTTATTAACGACCAACTTCTGTTATTGTGTGTTAA SEQ ID GTTTTTCATCTGTGCATCAAATCACAAAAAGAATAAATAGAGCTTTTTCTTTATCAGTCCCTT NO: GGGCACAGAAGGTCCTGAACACCCTGCTCTACAATGTTGCATCAGAGTTCAAACAACAAATAA 1217 AAAATATTAAGAGGGAAATCCCCATCCTGTGACTTGAGTTCCCTTAAGTCCTCTGGGGCTGGT GACCTCTTTTTGCTAATAG CTBP2 ADXCRSS.Hs#S3008063_at TCACCCAAGGGACCACACTGGGAAACCCAGTAGTTGTCTCGGCCATGGCACTAAGACCTTTGC SEQ ID ACCCTGGCCATCTTGTTCCGGGACAGCCAGCATCTGTGGTGTGGTATAGAGACAAAGCTGCCA NO: CCTCCAGGACACTTGCTCCTTCCTGGCCTTCCTGCTGCCCTGAAACCTGTGGCCTGTGTGTTA 2168 GTGGAAACATTCTCAGTTTCATTGCTCAGTAAACCTTAGGTTATCCAAACTGCAAATAAAATG TTCTCTACTTTCTAGATTTTTATAACTTGCTATTTTGAG CTBP2 ADXCRAD_BG614034_at TTCTGACTTTAATCTACCCCAAAGCAAAATGACCTGGACCTGGTTCAAGGGAGGGAAGTGAAC SEQ ID CTTGAAACTGTTTTGGCCAATAACCTTAACAAACAAAATGATATTTACCAAAAGAAGTGTTGC NO: AAATAGTCTCATGAGTTAAGAGCTTGATTTAATGGATCTTCTTTTT 2365 CTBP2 ADXCRAD_BG614034_x_at TTCTGACTTTAATCTACCCCAAAGCAAAATGACCTGGACCTGGTTCAAGGGAGGGAAGTGAAC SEQ ID CTTGAAACTGTTTTGGCCAATAACCTTAACAAACAAAATGATATTTACCAAAAGAAGTGTTGC NO: AAATAGTCTCATGAGTTAAGAGCTTGATTTAATGGATCTTCTTTTT 2366 CTBP2 ADXCRAD_CX866865_s_at GACTTGAGTCCCTTAAGTCTACAGGGGCTGGTGACCTCTTTTTGCTAATAGGAAAATCACATT SEQ ID ACTACAAAATGGGGAGAAAACTGTTTGCCTGTGGTAGACACCTGCACGCATAGGATTGAAGAC NO: AGTACAGGCTGCTGTACAGAGAAGCGCCTCTCACATCTGAACTGCATACTGAGCGGGCAAGTC 2503 GGTTGTAAGTTCAGTAAA CTBP2 ADXCRAD_AK024129_x_at ACTTAAGAAGTAATGTCCCTTGGCTGGGCGCGGTGGCTCATGCTTGTAATCCCAGCACTTTGG SEQ ID GAGCTGGAGGTGGGCGAATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGGCAACATGGCGA NO: AACCCCGTCTCTACTAAAAATACAAAAATTAACCGGGCATGGTGGCAGGCTATAATCCCAGGT 2829 ACTCGGGAGGCTGAGGCGGGAGACTCGCTTGAACCCAGGAGTTGGAAGTTGCAGGGAGCTG DSG2 ADXCRIH.2137.C1_at AGAGTACCTAGTTCATCAGCCGTCCAGTAAAGCAACCCAAGGAAACTGACTGGGTCTCTTTGC SEQ ID CTACCGTATTAACATTAAACATTGATGTTTCTGTATTCTGTACTTTACTGCACCCCAGCAGAC NO: TTTCAACAACTCATT 1191 DSG2 ADXCRPD.13409.C1_at TTTCATCGTGGCTTCCTTGGCCATACCTCCTACTCCATTTCGTCCTACTAGACTGCCCCCTTG SEQ ID ATCCACTGGCAGAAATGATGGCACCACCTTGTCTTCAGGTGGTGCTCCTTCATTATTCCAAGG NO: ATGCAGCATCTCTATGGTGCCAGGTATGGGGGTAAAGCCTTTGGCGCCCTTTCCGCAATGGCA 1640 CATCAGCAGTAAAAGTGGTACCAATAGCAGGAGCAGAAAGGCCAAAATCATGAGCGCAATTGC TGCGGGTCCCAGGCCCACATAGGAGTCATG DSG2 ADXCRPD.13497.C1_at AGTCAATGTAGAAGTTACGCGCATAAAAGTGTTCGATGCAGATGAAATAGGTTCTGATAATGG SEQ ID GCTGGCAAATTTTACATTTGCATCAGGAAATGAAGGAGGTTATTTCCACATAGAAACAGATGC NO: TCAAACTAACGAAGGAATTGTGACCCTTATTAAGGAAGTAGATTATGAAGAAATGAAGAATCT 1653 TGACTTCAGTGTTATAGTCGCTAATAAAGCAGCTTTTCACAAGTCGATTAGGAGTAATACCAG CTACACCCATTCCATCATGTCAAGTGAACATGTGACGAGGCTCATTTA DSG2 ADXCRAD_BQ887548_s_at TTTCATGTTTCCAATGTACCTGATTTTTCATGAGCCTTACAGACACACAGAGACACATACACA SEQ ID TTGATCTTAAAATTTTTCTCAGTCACTGATATGCAAAGGACCACACTGTCTCTGCTTCCAGGA NO: GTATTTTTAGAAATGTTCCACAATTTACTGAAGACATANAGATGATGCTGCTGCTTANGTGCC 2313 TTTTAGCAAGCTATGCAAACAATCCTGATAAAANCAGATACTTAGAGAGTCAATCTGGCTTCT GAGAA DSG2 ADXCRAD_BE171045_s_at GAGGAGTAGGTATTCTCTGAATTAACCATAGATTTGCTCACAGAGCTGAATGTGAAGCTGTGT SEQ ID TCATACTTGTTTCTGTGGCAGGTTTTTGTCTCTGCTCAATTTCCTTATTTATATCTATTTTTT NO: GACCCAGGCAAACTTCAGCTAG 2324 GPX4 ADXCRIH.2240.C1_at ACCAAGTTCCTCATCGACAAGAACGGCTGCGTGGTGAAGCGCTACGGACCCATGGAGGAGCCC SEQ ID CTGGTGATAGAGAAGGACCTGCCCCACTATTTCTAGCTCCACAAGTGTGTGGCCCCGCCCGAG NO: CCCCTGCCCACGCCCTTGGAGCCTTCCACCGGCACTCATGACGGCCTGCCTGCAAACCTGCTG 1246 GTGGGGCAGACCCGAAAATCCAGCGTGCACCCCGCCGGAGGAAGGTCCCATGGCCTGCTGGGC TTGGCTCGGCGCCCCCACCCCTGGCTACCTTGTGGGAATAAACAGA INPP4B ADXCRAG_BC005274_at CTTACTCACTGTGATCAAATGGTGAATATGTACCAAGACATTCTGACAGAACTTAGCAAGGAA SEQ ID ACAGGGTCCTCTTTCAAATCAAGCAGCAGCAAAGGAGAGAAAACATTAGAATTTGTTCCAATA NO: AATCTACATCTGCAAAGAATGCAGGTACACAGCCCTCACTTGAAAGATGCTCTCTACGATGTC 919 ATCACTGTGGGAGCCCCAGCTGCCCATTTTCAGGGATTTAAGAATGGTGGTCTTCGGAAGCTA CTCCATAGATTTGAAAC INPP4B ADXCRPD.8849.C1_at GATGATCACAGATGTTTCCCAAAATCTAGGAACTACTTCAATTCATCATCAGCATATGGCTCT SEQ ID GAAAGAAATCCATTTTAAAAAATCTTACATGATTCAGTACTGTCATTTCTAGTTCTAAGCTTC NO: TATGTGTTGAGCCTAGCTGATTGAGATGGGTTCACAAAGGGTAAATTTCATTCATGAGTATTT 1453 AAATGTTTCTGAGGAAACATGGATCATTTCAATAGGACTAG INPP4B ADXCRPD.12698.C1_at CTCAGACCCTGCCAAATACCATTCTAATTCTGTTCTGTTTCTATGAGTTTGACTTTTTTAGAT SEQ ID TCCGCATGTGAGAACATAAAGTATTTGTCTTTCTCTGTCTGACTTAGCATAATGCCCTCAAGG NO: TTCATCCATTTTGTTGCAAATGACAGAATTTCTTACTTTTCT 1616 INPP4B ADXCRPD.12698.C1_x_at TAAAGTCTGTACCTTTGATCATCATCTTCCCATTTCCTCCTCCCCTCAGACCCTGCCAAATAC SEQ ID CATTCTAATTCTGTTCTGTTTCTATGAGTTTGACTTTTTTAGATTCCGCATGTGAGAACATAA NO: AGTATTTGTCTTTCTCTGTCTGACTTAGCATAATGCCCTCAAGGTTCATCCATTTTGTTGCAA 1617 ATGACAGAATTTCTTACTTTTCTTTGCCTGAAATAAT INPP4B ADXCRSS.Hs#S3748650_at AATTCTAAGCAATGATATGTGGACTAATTCGATGATCTACATGGAGGTTTACTGCCTTTGAAA SEQ ID GAAGCAGTGATGACTCGAAGCCTATGTGGCCTCATTAGTGAAAATAATTTCAGAGGAACTTTA NO: TCTTTGACAGGATTTACAGCTGGATAGATTAGGAAAAATAATTCAATGGCATAGGATATTTGG 2199 CCTTTTACAGGGCATTTCATGACATACTTGTGAAAGATGGAGAAATATAGGCCATGCAATGAT ATG INPP4B ADXCRAD_CB852249_at GGTGCCATATTGCTTTGTATAAGTTATTTTCCATCAAGGATTTGTGTCTGCTTTGTGTGCTGC SEQ ID TATATAATAATTATGTCTTGCTGAAGTTCTTCTGCTTATTGAATTCCTCTACTGAAGTTCCTT NO: ACTTATTCAAATAAGTAAGGTAGGAGGTACTTAGTCAATTGAGCAGCTAATTGGCTAAAAGTG 2386 TCTTGAGCACAAGATAAGCATGTACTGAAAAACTGAGTATCTCTTGTCCATTGTTA INPP4B ADXCRAD_BG199926_s_at CACTTGAACAATGCTCAATCTTGAGAGATGAGCACCAGTTACACAAGGACTTCTTTATCCGAG SEQ ID CGCTGGATTGCATGAGAAGAGAAGGATGCCGCATAGAGAATGTACTGAAGAATATCAAATGCA NO: GAAAGTATGCTTTCAACATGCTACAGCTGATGGCTTTCCCCAAGTACTACAGACCTCCAGAGG 2625 GGACTTATGGAAAAGCTGACACCTAAGTTTACCAACATGTTA INPP4B ADXCRAD_BG199926_x_at ACATCGATGTCAGTGACACTTGAACAATGCTCAATCTTGAGAGATGAGCACCAGTTACACAAG SEQ ID GACTTCTTTATCCGAGCGCTGGATTGCATGAGAAGAGAAGGATGCCGCATAGAGAATGTACTG NO: AAGAATATCAAATGCAGAAAGTATGCTTTCAACATGCTACAGCTGATGGCTTTCCCCAAGTAC 2626 TACAGACCTCCAGAGGG JUP ADXCRAG_AF233882_x_at ACAGAGCAAGAACCCGTGTCTTAAAAGAAAAGAAAAACAGGAGGCTGGGTGCAGTGGCTCACA SEQ ID TCTGTAGTTCCAGCACTTTGGGAGGTGCAGGCAGAGGCGGAAGCGGAAGGATCACTTGAGGCC NO: AGGAGTTTGAGACCATCATGGGTAACATAGTGAGACACCCATCTCTTACAAAAAATT 873 JUP ADXCRIH.2082.C1_s_at AGCTGCCCTAGCTGACCCCGAGAAGTGCTCTTGGCTGACCCCTCTGGTGTGTGGTGAGGGGCT SEQ ID TTCTCTTCCCCTTCCTGTTTCAGACCCCCCCATTTCCCGCACATGGTGTGGGGGGCTGGGGGA NO: GGTCCAAGCAGAGTGTTTTATTATTATCGCTTTATGT 1152 KDELR3 ADXCRIH.3560.C1_at GTATGTGACCAAAGTCCTTAAGGGAAAGAAGTTAAGTCTTCCAATGCCAATCTGAGGACCTTC SEQ ID AGAGACAGTCTACGCCTTAACAAGCACATGAAGGAAACTATTTTGAATGTTCTCTTTGGCAAC NO: TTATCCATAATTTGGGATCAAATGTTAAAACCAGAAAAGTGTTTAGTGTGGATTTCAGCA 1221 AACCTG KDELR3 ADXCRPD.11126.C1_at AGAGGAGGGACATTGTTCCAGATTGGGGTTGACTTGCCCATCATGAGTCTTGCCCTCAGGCCT SEQ ID TGGAGAACAATCATTTATGTTTTTTATTTCGTCGGTAAGACACCTTAAGGTTTCTTGTTGCAG NO: TGAGGCACCATCTTTGTGCAGTTGGCCGAGGTTTTTTATGACCTTACAATGGGTCTTTAAGGG 1428 CGATCTATTGATGA KDELR3 ADXCRPD.3569.C1_at TACTTAGGCGAGTACCATTTGCACAATCACTGTTTTACTTATGAGCAGATACAGATATATCCA SEQ ID AACCCTTACCTACTAGGTATCCTGCTAGGGTTTTCAATTCCAATTCTTGTATTAAGTTTTTTC NO: CTTTCAGTTTTAGGTGCGAAAGTAATCAGTCAATCCAATATCCCCCATCTTTGTCTTGAAACA 1599 AAAACTGTTTTAAGACGTCTACGTTGAATTATTCAGAGAATTAAGCAATAAAAGCTCACACCT TAT KDELR3 ADXCRPDRC.11126.C1_at GACCTTTTCATCAATAGATCGCCCTTAAAGACCCATTGTAAGGTCATAAAAAACCTCGGCCAA SEQ ID CTGCACAAAGATGGTGCCTCACTGCAACAAGAAACCTTAAGGTGTCTTACCGACGAAATAAAA NO: AACATAAATGATTGTTCTCCAAGGCCTGAGGGCAAGACTCATGATGGGCAAGTCAACCCCAAT 1932 CTGGAACAATGTCCCTCCTCTTAG KDELR3 ADXCRSS.Hs#S3732256_at GGCTTAACCAGCTAGACATTCCTCTAAATACATACGTAACAAAAATTGATGGCAGGAGATTTT SEQ ID ATTGGGATCACTGGATACCTACACTCAACAGGCAGAACTTGGCTAATTCCATTTATACCACTA NO: CTGAGACAGTGAAGACAAATTAAGAATCAGAACAGGAAGCACATAGCATAGGGATACCCGTGT 2149 CAGCGACATATTTAATATGCCCCTCAGCTTAAGACTCAATACTGAACAGACCAAAAGGCCACC TCAATTGCCGCTCCCGCCACACTTGCTATTGAAACT KRT18 ADXCRIH.1401.C1_s_at CACCAAAGTTCTGAGGCATTAAGCCAGCAGAA SEQ ID NO: 1151 LAD1 ADXCRAG_NM_005558_at TCTTCTCACATTAAGGTGGTGGCTTGCCACTCAGCAGTCCTAGCTTGGTGACTGGGAACTGCC SEQ ID ACATACAGGGCCAGGCCTACCCTCCTTCCCCACAAGCCCCCTCCAACCCCCACCCCCATGCTC NO: TGGACCTCATGGCTCCTATGAGCTTGGAGCATGGTGAACCATCAGAGAATCTAGAACCAACCA 1029 AGCTAGGAACATCAGCCTGGTGCCCTGTTAA LAD1 ADXCRIH.3628.C1_s_at AAGTGCCTCTTTGTCTATGATGTCCCCCTTCTCTGAGGCCTGGACCCACCCATCTTTGTCCCT SEQ ID GGGGCCTGCTCCCAGCCACTGAGGCCCGCTCTGCCAGGGGAGAAGGAGCTGCCGTGCGTCTTC NO: CCTGTGCCCCGTCTCCCTGCTTGGTTCTCCCCTCCCTTCCCTGGCCGGCTGCCATGGCCAGGA 1108 GCTAAGTGCCTTTTTGTGTGCAACCACTTACCCTTTCTCTGAAAAACCTGTTCTCAGGAAGGA TCTGATAAACTCATTTA LAPTM4B ADXCRIH.1454.C1_s_at TATATTTGATATACTTCTGCCTAACAACATGGAAAAGGGTTTTCTTTTCCCTGCAAGCTACAT SEQ ID CCTACTGCTTTGAACTTCCAAGTATGTCTAGTCACCTTTTAAAATGTAAACATTTTCAGAAAA NO: ATGAGGATTGCCTTCCTTGT 1153 LGALS3 ADXCRIH.184.C1_at AATCACAAACATCAGAATGCCCAGACTGTACCGCACTTCCCGCTACTCAGAGGATTTCTCAGC SEQ ID TCCTGCCGGCAGAGTCCACTCCCTTCCGCCCTGGGCCTTTTGGTGAAAGGGTTACTGTGAGTG NO: AGTCCCAGGCCTCGCTCTGCCTGGCTTTCTTCCCAAATCTGCTGCTGGAAAAACAAGGCTCCA 1299 GCTTGCAAGCCCTCATTGGACAAATGAGTCCA LGALS3 ADXCRIHRC.184.C1_at GAATCTAAACCTTACATGTGTAAAGGTTTCATGTTCACTGTGAGTGAAAATTTTTACATTCAT SEQ ID CAATATCCCTCTTGTAA NO: 1334 LGALS3 ADXCRIHRC.184.C1_s_at AATACAAGTACTGGTTGAACCTGACCACTTCAAGGTTGCAGTGAATGATGCTCACTTGTTGCA SEQ ID GTACAATCATCGGGTTAAAAAA NO: 1335 LGALS3 ADXCRSS.Hs#S1444631_at TTTCTCCTGTTCCTTCCCATGTCAAGGCTCCAAAAGCACAAGATGCTTCACAGCTGTTGTAGG SEQ ID TGCTCCAGCAGTGAGGGGAGGAGGGCAGCTGGGCCCCTGAGGCATGGGTGGAGTTTTCTTAAG NO: CTTAGGATCACCTGTGCCATGGCCTGAATTACCTGAACCTTGAAACAACCAGAATATCCTTCT 2069 CTTTGATTTGCCCACCTGTGATATTTACTCAATCACTTTTAGAAATGGCATCG LITAF ADXCRIH.2736.C1_s_at TCTAGGTTGGCTGCTGTGTCATCTTTGAAGTCAAGACAAAGCTGGGCTCGACCTTCAAGGGTC SEQ ID CTCGTTTTGATAATACTTCAGAATAGGGAACTCATGTGAATACTACTATGTAGAAATAAAACC NO: TAGACCTTGAGCGAACATCTGTATATTGGTTGAAAACGATAGTGGTAACCATTGATCCCCCTT 1134 CATTTGATGTTTGGAAAATTCCAGTAATTATCATTTTTGCAACGAATATGGATACCACA LITAF RDCR260_H04_s_at GTAACTGCAGACTTCATTAGCACACAGATTCACTTTAATTTCTTAANNNNNNNNNNAAATACA SEQ ID AGGAGGGGGCTATTAACACCCAGTACAGACATATCCACAAGGTCGTAAATGCATGCTAGAAAA NO: ATAGGGCTGGATCTTATCACTGCCCTGTCTCCCCTTGTTTCTCTGTGCCAGATCTTCAGTGCT 1341 CCTTTCCATACAGGGATTTTTTTCTCATAGAGTAATTATATGAACAGTTTTTATGACCTCCTT TTGGTCTGAA LITAF ADXCRPD.553.C1_at GTTCACCCGGTGAACTATTTATGAGTTCTTCTGGTGTGAAGAAAGGGCTCATGTTGCATTTCC SEQ ID AGCCATTGCTACAAAGAACCTTTATTTGTTCAGTAAGCGGTAGAAAATCCTTCCGCGATTAAA NO: AACTTCAGACTTGCTGAATATCCTGCAATGTCAAGATGACCGATGTTGAGTTGGGTGGATTTG 1562 CTAACGAGTCAGATTTGAACATGAGGCTATTGGAACACAATAGGCGTCATTGATGGCGGCAAG CCATAGCTTTCAAGTT LITAF ADXCRAD_BX410303_at AAGCACATTTTTGAGCCATGTCTGGGTACCATGGTGGCGGAATGCTTGGGGACC SEQ ID NO: 2339 LITAF ADXCRAD_BX410303_x_at GGGCCTGAACATAATTTCAAGAGGAGGATTTATAAAACCATTTTCTGTAATCAAATGATTGGT SEQ ID GTCATTTTCCCATTTGCCAATGTAGTCTCACTTAAAAAAAAAAAAAAGAAAAGAAATGGATAA NO: TTTCATCTACTGCCTTTACTTGGGGGTTAATGTGATTCTTAAACACCTTCATCATGGAACTCT 2340 CAGAGTGGGGGTCCGTTTTTGTTTTCCTGGTGGGGGGGTTTTTGAAAGAATAAGGAAAAGCAC ATTTTTGAGCCATGTCTGGGTACCATGGTGGCGGAATGCTTG LRP5 ADXCRPD.3405.C1_at TGGACCCCGCTCACGGGTACATGTACTGGACAGACTGGGGTGAGACGCCCCGGATTGAGCGGG SEQ ID CAGGGATGGATGGCAGCACCCGGAAGATCATTGTGGACTCGGACATTTACTGGCCCAATGGAC NO: TGACCATCGACCTGGAGGAGCAGAAGCTCTACTGGGCTGACGCCAAGCTCAGCTTCATCCACC 1572 GTGCCAACCTGGACGGCTCGTTCCGGCAGAAGGTGGTGA LRP5 ADXCRSS.Hs#S1910362_at ACCTCTTGAGCGCTTTTCTATGAAGCATCCTGTTTAAGCCTCGCACTTCTGTGATGTGGAGGT SEQ ID GCAGTAATTATCCCCATTTCACAGACAGGATGTTGAGGTCAGAGGGGTTGAGTGATTGTCATG NO: GGCCAGGTCTCAGCCAGGCTTGCTAACCCTGGAGTCTGGCGTCTGCTCTGAAGTGGTCCTCTC 2120 AGCTGGAGACTGACCTGGCCTTTTGCTTGTGATGTCGGCCTTAAAAATTTTGGGGGATGCTCT CGGACTTTTGGATGGGTTCA LRP5 ADXCRSS.Hs#S2985193_at GGTGCTATTGAGTTCCATCATGTCCTTACTGATTTTCTAACTGCTGGATTTCACCATTTCTGA SEQ ID TGGAGGGGTGTTGAAGTTTCCAACTATAATAGTAGATTCATCTATTCTCCCTTGCAGTTCTAT NO: CAGTTTTTGCCTCATGTATTTTGACACTGTTATTAGGCAAATACACATTAAGGATTGTTATGT 2150 CCTCTTGGAATATTTCTTCCTTTATCATTATGTAATACCTCTCTTTAGCCTTGATAACTTTTC TTGTTATGAAGCCTGCTCTATCTGCAAGGAAC LRP5 ADXCRSS.Hs#S3011054_at TGGAACCACTGTTTTACACCACAGGTTTAGGGACTGTTTGTGAGTTAAGGGTTCCTTTCGGTG SEQ ID ATCTGTGAACTTGGTCTTTGCAGTACCTAGATCCTGCCTTGGAGATTATTTAGTAGTGGGGAT NO: TATTTAGATGGTATACTTAACCATTTTTCAGATGCCTGAAGACTGAACTTTAGAAGCATTTGT 2177 TAATTGATTTTATAAAATATCTTAGGACTTTTTTTTCTTAACCTCATGAAAATACATTACCAT ACTGTGCTGAAACTAA LRP5 ADXCRAD_BM790129_at ACAGGCCCTACATCATTCGAGGAATGGCGCCCCCGACGACGCCCTGCAGCACCGACGTGTGTG SEQ ID ACAGCGACTACAGCGCCAGCCGCTGGAAGGCCAGCAAGTACTACCTGGATTTGAACTCGGACT NO: CAGACCCCTATCCACCCCCACCCACGCCCCACAGCCAGTACCTGTCGGCGGAGGACAGCTGCC 2497 CGCCCTCGCCCGCCACCGAGAGGAGCTACTTCCATC LSR ADXCRAD_BI837070_at TTAATTGGAAGGAACACGTGAGTTGAAGCCCTGGCCGATTACCCCTTCCCGGAGTCTAATAAA SEQ ID AGGGTATTAATCACAAGAAAAAGAAAAGAGCGAAAAGAGACGGAGAACATGCGAGAAAGGACG NO: ACAG 1046 LSR ADXCRAD_BI837070_s_at TACTCGGAGACCGACTCGCAGGCGTCCCGAGAGCGCAGGCTCAAGAAGAACTTGGCCCTGAGT SEQ ID CGGGAAAGTTTAGTCGTCTGATCTGACGTTTTCTACGTAGCTTTTGTA NO: 1047 MLPH ADXCRPD.10614.C1_at CTTCGAGGGAGTACTTTAAGATGACTCCACTCAGCCTCAAGGTCACTCCCTGCACATGTCCTC SEQ ID AGTTCCCTGAGGCTAGGGACAGCCCACTAGTCCCTCACAGATGAGTCCTGCTCAGAGTAGGCA NO: GCCCCTCACAAGGCTGAGGGCCTGGAGGAGGCTGAATACTGGGGCCTCTGGGTGCCACTCCAA 1460 TCCGGAAGAGCAGCCGACCAGCATCTCACCTTCCAGACACGGCGTCCTGGCTGAGCTCTGCCC GCCTGGAGGCTCCCACAGGATGGCCATGGATTTTTAGCTGCCATCTC MLPH ADXCRPD.13135.C1_at AGGATCCGAGTGGTAGTGTTTCTGAGAGTCAGGGTCTAGGTGCTGGAGTGCGCACGGAGGCCG SEQ ID ATGTAGAGGAGGAGGCCCTGAGGAGGAAGCTGGAGGAGCTGACCAGCAACGTCAGTGACCAGG NO: AGACCTCGTCCGAGGAGGAGGAGGCCAAGGACGAAAAGGCAGAGCCCAACAGGGACAAATCAG 1588 TTGGGCCTCTAGCGT MLPH ADXCRPD.15019.C1_at AATAGACAACTTGATTCTCCTCTTCATCCTGTTGTCTTCAGGCTAGGAGACTAGGAGATGCTC SEQ ID AGCCAGCCAAGGATGTCCCATGGGTCTCTACCTGGCCACCCTGAGAGGTCTCTATGCTGGCCT NO: CACCCAAGAGGTCTCTATCCTGGCCACACTGGGGAGGTCTCTATCCTGGACACCCTAGTCCTC 1697 CACTGTACCCTGCATCCACAGGTCCCTGGATGGACTTGGATGAGTTGGCTCTTCCCCTTTTCT CAGAATAACTGTAGGCCTGTGGTTAC MLPH ADXCRPD.1115.C1_s_at GAAGGAGCACCCTCCACATGGACTCCCACCTGCAAGTGGACAGCGACATTCAGTCCTGCACTG SEQ ID CTCACCTGGGTTTACTGATGACTCCTGGCTGCCCCACCATCCTCTCTGATCTGTGAGAAACAG NO: CTAAGCTGCTGTGACTTCCCTTTAGGACAATGTTGTGTAAATCTTTGAAGGACACACCGAAGA 1895 CCTTTATACTGTGATCTTTTACCCCTTTCACTCTTGGCTTTCTTATGTTGCTT MLPH ADXCRSS.Hs#S1921395_at GTATCCAGGCAGAACGGTACCCTGAGGGCCAGCACAGCAGGAAGAAAGACAAGGACATGTGTA SEQ ID CTGCCCTGCATTCCAGGCTGGAGGAGTCCTCTTAAATAAGAGCCCAGAAGTGTCCTGGGGCAG NO: CAGCTGGAGGCTGATATATTTCAGAGGCTGAAATTAGGGGAAAGGAGAACTGTACTGTGCTTT 2103 AGATTCTTTAAAACATAACTTCCCTTCTTCATAGCCAAGAGACAGGAACGGA NR2F2 ADXCRAD_CB217549_s_at ATTATAATTGTTGATATTTTCCCTTTTTAAAAAATACCATTGAAATCAGCATGACAAAAATAA SEQ ID CACTGTTGGCACTTATAGGTAACGTGATTGATTCAGTATCTTAGAGTTTACAGTTTGTGTTTT NO: AAAAAAACTGAAGGTTTTTTTTTAAGTGCAACATTTCTGTATACTGTAAAAGTTATAATAACT 979 GAACTGTTTGGTCGAGTCTTTGTGTGTTA NR2F2 ADXCRPD.4673.C1_at GAATTGCCATATACGGCCAGTTAAAACTGCTGCCGGACAGTAACATATCCCGGATGAGGGTTT SEQ ID CGATGGGGGTTTTACCTACCAAACGGACGAAAAACAATTGCTCTATGACTGAGGAGGAGACGG NO: TGCGGAGGGAAGGGAGGCGAAGCAAAAGCTTTCCGAATCTCGTCGGCTGGTTGGGGTACTGGC 1691 TCCTAACGTATTCTTCCAAAGCACACTGAGACTTTTCCTGCAAGCTTTCCACATGGGCTACAT CAGAGAGACCACAGGCATCTGGAAGA NR2F2 ADXCRPDRC.4673.C1_s_at ATCCGGGATATGTTACTGTCCGGCAGCAGTTTTAACTGGCCGTATATGGCAATTCAATAA SEQ ID NO: 2001 NR2F2 ADXCRAD_CB956496_at GCGAGCGAGATCTTTGGAGAGATTTTTTTTTTTGCCTCCTACTTCTGTCTTGAAGCCAGACAA SEQ ID TCGACTTCAGCTCTCCCTCCCCTCCCTCTTTCTCCACGTTCTGCTCCCACTCGCTCTCCTGTC NO: CCCTTCCCCTCCCCTCCCGGCGGAAAGCCCCCCGAAACCAACAAAGCTGAGCCGAGAGAAACA 2487 AACAAAACAAACACACCGGGCCAGACAAGCCATCGACAAAACTTTGCAAAGTCAACC NR2F2 ADXCRAD_CB956496_x_at GCGAGCGAGATCTTTGGAGAGATTTTTTTTTTTGCCTCCTACTTCTGTCTTGAAGCCAGACAA SEQ ID TCGACTTCAGCTCTCCCTCCCCTCCCTCTTTCTCCACGTTCTGCTCCCACTCGCTCTCCTGTC NO: CCCTTCCCCTCCCCTCCCGGCGGAAAGCCCCCCGAAACCAACAAAGCTGAGCCGAGAGAAACA 2488 AACAAAACAAACACACCGGGCCAGACAAGCCATCGACAAAACTTTGCAAAGTC PPAP2B ADXCRAG_AF480883_at GCTCGTAACACAACTCTCATCTCAGGCTCTTCTAAAGAGCTTTTGTATTCTAAAGAGGATTTT SEQ ID TCCATCAGAGAGGTAGGAGCTGTAGGAACCCCGAGGGCAGATAAGCAGCCCTCACTCTAGATA NO: AGGTATGCTGGGGGAGCTTACTGAGGGAATCCTGTACACAGCCCACATCAAAGGAAGGCTGAG 788 AATGGCCTGTGGCTCC PPAP2B ADXCRAD_CD678016_s_at TAAACTGTGTCTCGACCTGTGTTATTTACATTAGCTGCTTAAAAAAGCATTGAGTTAATTTTT SEQ ID TTAAATATCAACTAAAATATCATAGTTCTGTGGTAGACATTGTTTTATAATGAAATAACTGCA NO: ACTAGAGAAAACTGTATAAAAACATTAAATTGTCAGTATTTTTGTAAGGTTCCATTTTGTAAA 1024 GAGAATAATATTCAAAGACTTTTGTAGCATACAAAGTGAAAACTTGTATCTGCGAAACTATAC TTGTATTAAATGTGCTTTT PPAP2B ADXCRPD.13412.C1_s_at ATGTTCTGGCAGGATTTGCTCAAGGAGCCCTGGTGGCCTGCTGCATAGTTTTCTTCGTGTCTG SEQ ID ACCTCTTCAAGACTAAGACGACGCTCTCCCTGCCTGCCCCTGCTATCCGGAAGGAAATCCTTT NO: CACCTGTGGACATTATTGACAGGAACAATCACCACAACATGATGTAGGTGCCACCCACCTCCT 1641 GAGCTGTTTTTGTAAAATGACTGCTGACAGCAAGTTCTTGCTGCTCTCCAATCTCATCAGACA GTA PPAP2B ADXCRSS.Hs#S524340_at TGACTGATAGCTGCCGCTTATGGTTACTTAGTAAAAACTCCTGTTGCTAAATGGCTCAAATGG SEQ ID ATGTCTGTGTGTTTATTTTGCCATCTAATACAAAGCATAAATTTTTCTTACTCCAGTAGCTCA NO: TCAAACCCTTGAATCTTTCATCATAAGCACATTGAGGCAGGAACTATGCCTGTGCCATCCTCA 2129 CACCTTTGCAAGTGGCACTCAATAAATGTTTCTCAAGTATTGTTCAGACTCAGTGAGGGTCAC ATCCCCAGGAGGAA RRBP1 ADXCRAG_AF006751_s_at AGAAGAAGTTAACAAGTGACCTGGGGCGCGCCGCCACGAGACTGCAGGAGCTTCTGAAGACGA SEQ ID CCCAGGAGCAGCTGGCAAGGGAGAAGGACACGGTGAAGAAGCTGCAGGAACAGCTGGAAAAGG NO: CAGAGGACGGCAGCAGCTCAAAGGAGGGCACCTCTGT 843 RRBP1 ADXCRAG_BC009700_x_at ACTCAGAATCAAAGCAAAAAGGCTGAAGGAGCCCCAAACCAGGGCAGAAAGGCAGAGGGAACC SEQ ID CCAAACCAGGGCAAAAAGACAGAGGGAACCCCAAACCAAGGGAAAAAGGCAGAGGGAACCCCA NO: AACCAAGGCAAAAAGGCAGAAGGAACCCCAAACCAAGGCAAAAAGGCGGAGGGGGCCCAGAAC 928 CAGGGTAAAAAGGTAGATACAACCCCAAACCAGGGGAAAAAGGTGGAGGGGGCCCCAACCCAG GGCAGAAAGGCCGAGGGGGCTCAGAACCAGGCCAAAA RRBP1 ADXCRPD.7803.C1_s_at GAGGCGTTTGACGTTCTAGGTTATCCCTCCGCAAGGGGATTCTCTGCCTGGCTTGCTGATGTC SEQ ID ATATCTGGTGGGGAGTGGATTTAGATCTGACACTTTTTCTGCTCTTCAGAAGCAGAAGCACAA NO: GCCCAGTATCCCAATTCTGGTTTAATCTCAAA 1876 RRBP1 ADXCRAD_CB159041_at TAAACACTATCCTGGGCGCAGCCCCGGGCCACCGCCGAGTGACGCCAAAGCCCTGGTTGACTC SEQ ID TGACAGCCCCGTGGGTGTGTGGGAGGCCGGGCGCTCTGGGGTCTGTCTGTCAGT NO: 2360 RRBP1 ADXCRAD_CB159041_s_at AAAGCCCTGGTTGACTCTGACAGCCCCGTGGGTGTGTGGGAGGCCGGGCGCTCTGGGGTCTGT SEQ ID CTGTCAGTGCAATCGTTTAGTGTTTTTTCAGTGGGGCGGGGCGGGAAGCGGGTGGGACCGGGC NO: AGCCAGTTCTCAAAGGCTGTGGGGCCGACTGGAGGCCACAGCCCCTCACCCCTAGACGTTGCC 2361 AACCAGAACTGACGTG RRBP1 ADXCRAD_BQ778389_at TGGTGGTGAGTTTTCGCCATCTCCTTGCGCTGGTTGGCTAGGGCTTCTTCATATGACGTTTCC SEQ ID TTCATGGAGAAAGTCGACACCAGGAAGATGCCAATGGCAGAAACAACCATGAATCCTCCAAAG NO: ACCACAACCCCCAAGGTTTGAGTGTCGTAAATATCCATCCTGGCTTGCTTTC 2362 RRBP1 ADXCRAD_BQ931525_at CCATGAGAGAACAAGTCTCCTTAGAGCCACAAGAAGTAGACCCTTCCCAGAGCCCCCAGTTTT SEQ ID GTAAAATGAAACCCTGTGCTCCCCATTTT NO: 2363 RRBP1 ADXCRAD_BQ931525_x_at CCATGAGAGAACAAGTCTCCTTAGAGCCACAAGAAGTAGACCCTTCCCAGAGCCCCCAGTTTT SEQ ID GTAAAATGAAACCCTGTGCTCCCCATTTTGGATAAACCACTAATCCCG NO: 2364 RRBP1 ADXCRAD_CN262594_s_at CACAGTGAAGCATCTCGAAGAGATTGTAGAGAAGCTAAAAGGAGAACTTGAAAGTTCGGACCA SEQ ID GGTGAGGGAGCACACGTTGCATTTGGAGGCAGAGCTGGAAAAGCACATGGCGGCCGC NO: 2610 RRBP1 ADXCRAD_BE646396_at GAGCAGAGCACATACCTGGTCCGAACTTACAAGTCTCCTTATAGCTTCTCTACAATCTC SEQ ID NO: 2822 RRBP1 ADXCRAD_BE646396_s_at GCAGGTCTGCACAGGGCCCGTGGCTGGGTCTCAGGGTCCTCTGAGGTAGTCAATGTCTCTCAT SEQ ID TAAGGAAAAACAGGATGGACAAGATCCCTTGGCTTGAGAGAGAATGCCTCTCTTAAGGCACAC NO: GGTCCATGAGGAAGAAATCAGTGAAGTGTCCTCTGCATTAACGTCACTTTCAAAGAAGCTCCC 2823 NGGACATGAGAAAGAGTTCTCTGAGCAGAGCACATA SERPINB6 ADXCRIH.878.C1_s_at AGCTGCCATCATGATGATGCGGTGTGCCAGATTCGTCCCCCGCTTCTGCGCCGACCACCCCTT SEQ ID CCTTTTCTTCATCCAGCACAGCAAGACCAACGGGATTCTCTTCTGCGGCCGCTTTTCCTCTCC NO: GTGAGGACAGGGCAGTCTTGGTGTGCAGCCCCTCTCCTCTCTGTCCCCTGACACTCCACAGTG 1190 TGCCTGCAACCCAAGTGGCCTTATCCGTGCAGTGGTGGCAGTTCAGAAATAAAGGGCCCATTT SERPINB6 ADXCRPD.16952.C1_at CCATGTACTGGTCTGACTCATGATACAGTAGTAGAATCAGTAGAAGTGATGCTGTACAGAGCT SEQ ID AGGCCCTTTTTAAAAGGCCTGACAGCTGCCATGTTCACTCTCTTGTACACTGGCACCATGACA NO: GAAGGAAGTCCAGGCTATCCTGCCGAAGCA 1386 SERPINB6 ADXCRPD.11180.C1_at ATCCTGCTGCAACAAGCCAAGCCTTCCTGCGCCTGAACTCACAGCACACTCAGGACACCACCT SEQ ID TGCCTCATGGGCTGTGGGTGCATGCCCATCTACACCTTCACAGACAGGCTCACGGGTAGGGTC NO: AGGCTGCACATCTCTCTAGCCCTGCCGTGCAGTGGGTGTGGCAGCCCCAGCAGGGTCCAGAGC 1436 AGGAATGCAGCTGGATAGTCGGGAGGGGGGAGCTGGGGTATCTTCAGGCAAGTCGGAATCACA GAATCACATGTTAAAGTCCACCAAGCCCTTAGAGAGACCTACCATCA SERPINB6 ADXCRSS.Hs#S2986702_at TGCCCTGAGGCCATCTCTTTTAGAATCTTTTGCCAGCTGGAAAGGCTGGGAAGAAGAAACATT SEQ ID TTTATTCTCCACCCAGTACATCCTGGATTGGAAATAGTTCCTTTAAATTCTGCTTGAAAATGG NO: AACAGTTCCTTCATCTTTCTCTTCCCATGTGTTACCCTAGGCAGCAAAAAGAAGCCAGCTTCC 2167 TCCTGGACCCCTTAGCCAGATGCAGGAGTTCCCGGGGGAGGCACTCCATCCTCCCTGTCACTG AGGGTGACCTTCTTTCCACTT SFN ADXCRIH.2281.C1_at CAGAGCTGAGTGTTGCCCGCCACCGCCCCGCCCTGCCCCCTCCAGTCCCCCACCCTGCCGAGA SEQ ID GGACTAGTATGGGGTGGGAGGCCCCACCCTTCTCCCCTAGGCGCTGTTCTTGCTCCAAAGGGC NO: TCCGTGGAGAGGGACTGGCAG 1253 SFN ADXCRIH.2281.C1_x_at CAGAGCTGAGTGTTGCCCGCCACCGCCCCGCCCTGCCCCCTCCAGTCCCCCACCCTGCCGAGA SEQ ID GGACTAGTATGGGGTGGGAGGCCCCACCCTTCTCCCCTAGGCGCTGTTCTTGCTCCAAAGGGC NO: TCCGTGGAGAGGGACTGGCAGAGCTGAGGCCACCTGGGGCTGGGGATCCCACTCTTCTTGCAG 1254 CTGTTGAGCGCACCTAACCACTGGTCATG SFN ADXCRPD.9737.C1_at TGCTTTTCTGCTCAATACTGGACAGCACCCTCCAGGCAGCCCTCTGGCCGCCCACCACGTTCT SEQ ID TATAGGCTACTGAGAGCAGGTTTCGCTCTTCGCAGGAGAGCTCCTCGCCCTTCTCCACGGCGC NO: CTTTCATGAAGGCTGCCATGTCCTCATAGCGTTCGGCCTGCTCTGCCAGCTTGGCCTTCTGGA 1506 TCAGACTGGCTCTCTCCATGGCTCTGGGGACACACAGCGGGCGGCGGGCTAACTGCTGCCTG GCCTCGTG SFN ADXCRPDRC.9737.C1_at CCCAGAGCTGAGTGGTGCCCGCAAACCGCCGGCTGCCCAATCAAGTACCACAACG SEQ ID NO: 1949 SFN ADXCRPDRC.9737.C1_s_at TCTTCCACTACGAGATCGCCAACAGCCCCGAGGAGGCCATCTCTCTGGCCAAGACCACTTTCG SEQ ID ACGAGGCCATGGCTGATCTGCACACCCTCAGCGAGGACTCCTACAAAGACAGCACCCTCATCA NO: TGCAGCTGCTGCGAGACAACCTGACACTGTGGACGGCCG 1950 SFN ADXCRPDRC.9737.C1_x_at TCTTCCACTACGAGATCGCCAACAGCCCCGAGGAGGCCATCTCTCTGGCCAAGACCACTTTCG SEQ ID ACGAGGCCATGGCTGATCTGCACACCCTCAGCGAGGACTCCTACAAAGACAGCACCCTCATCA NO: TGCAGCTGCTGCGAGACAACCTGACACTGTGGACGGCCGACAACGCCGGGGAAGAGGGGGGCG 1951 AGGCTCCCCAGGAGCCCCAGAGCTGAGTGGTGCCCGCAAACCGCCGGCTGCCCAATCAAGTA CCACAACG SFN ADXCRAD_CN335041_at CCCTGCTGCCTCTGATCGTAGGAATTGAGGAGTGTCCCGCCTTGTGG SEQ ID NO: 2754 SFN ADXCRAD_CN335041_s_at CGCCTTGTGGCTGAGAACTGGACAGTGGCAGGGGCTGGAGATGGGTGTGTGTGTGTGTGTGTG SEQ ID TGTGTGTGTGTGTGTGCGCGCGCGCCAGTGCAAGACCGAGATTGAGGGAAAGCATGTCTGCTG NO: GGTGTGACCATGTTTCCTCTCAATAAAGTTCCCCTGTGACA 2755 SFN ADXCRAD_CN335041_x_at CCCTGCTGCCTCTGATCGTAGGAATTGAGGAGTGTCCCGCCTTGTGGCTGAGAACTGGACAGT SEQ ID GGCAGGGGCTGGAGATGGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCGCC NO: AGTGCAAGACCGAGATTGAGGGAAAGCATGTCTGCTGGGTGTGACCATGTTTCCTCTCAATAA 2756 AGTTCCCCTGTGA SLC25A1 ADXCRAD_CN295781_s_at ACTGTGTCCCAGTGTCTGGCCCAGCCATGGCTGGATGTGCATCTGGCCTATGACCCTGTGCCT SEQ ID GTGTTTCATGTTCTGTGTCACGTGACCCTGTGCCCCGCCTCCCGGGGTGCCCGTGTGGCCTGG NO: GTCCTCGGCCCTGTAGCCCTGGCCCGGTCCCAGTCCGGTGCCTTCCACCCTGCCCTGGCCTAC 2501 CACAGCTGCCTCCGGGCCTCGGCCTGGCTTCACCGCATTCCAGGGGCTGCAGCCCCCTGCTTC TCCCGCCATTGGCCTTAACTGGCCCTCGGGC SORL1 ADXCRAG_U60975_s_at TGAAGATGCCCCTATGATAACTGGATTTTCAGATGACGTCCCCATGGTGATAGCCTGAAAGAG SEQ ID CTTTCCTCACTAGAAACCA NO: 1069 SORL1 ADXCRPD.18092.C1_at CTGGGTTGCCAAAGGTAAAATATATAAAAGAGAAGCCTCTGACTTGGTTCCTGCTTCTGGTCT SEQ ID CTCTCCATCAAACGCATTCTGCCCACTACTTATCCTTCCCAAAGATGAACTTTCATCACATGA NO: CATCAGTGGTTCCCAACTGCTTCTCCGATAAAGTCCACAAAGCCTTTCTGTCCTGGCGCTGCC 1871 CACTCATCTAACTTCACCTTGCACCCTGTGCCCATGCCCATTCTCCATAACTCAAACCAGTTT CCTGCCAT SORL1 ADXCRAD_BX089897_s_at TTTCTTCCCCGACTGAAAGATGGCTTTGTCCGTTGAGTTGAAAACTATTAAGTCCTGCCTTCC SEQ ID TCACTTTTCATCACGTGGCTTCTGTTTTTGAATTCCTTTTTGTTTTCAGTGATCCCACCACTA NO: GATATCCACATTGACAGCTATGGTGAAAATTATCTAAGCTTCACCCTGACCATGGAGAGTGAT 2476 ATCAAGGTAATGTGGGAATTTCAAGCCAGCAGCTGGATGGGGCTTTATTTTGTATGGGAACTG AAAGGACATAGCACAGTAAGACTGG SQLE ADXCRAG_AF098865_at GATTGTTACCATAAATTAGTGCTAATGCTGAGGAG SEQ ID NO: 856 SQLE ADXCRAD_CB106889_s_at TGGATTACAAAACCTCGAGCCCTTCTCAGTAGTGGTGCTGTATTGTACAAAGCGTGTTCTGTA SEQ ID ATATTTCCTCTAATTTACTCAGAAATGAAGTATATGGTTCATTAAGCTTAAAGGGGAACCATT NO: TGTGAATGAATATTTGGAACTTACCAAGTCCTAAGAGACTTTTGGAAGAGGATATATATAGCA 857 TAGTACCATACCACTTATAAAGTGGAAACTCTTGGACCAAGAT SQLE ADXCRPD.8241.C1_at CAGAGGCTTCTTTTTCCGCGGACGGAGACACTGTACAGCCCAACCTCGGGAAAACGCCAACGC SEQ ID AGACGGATTCTCCAACAAAAGATGGGCTCGGACTCAAGAGTGCGGCTCCAGGGCAATGCAGCC NO: CAACCTAAAGATTTAGAAGGCTTCCCGTTTTCGTGGGCGCCAGAGCCGCCCACGGCGACTGCA 1825 GTTTCCCACCGATTAAAGGTGGGTTTCACGGTAACTCCCTCAGATTGCGGCGGCGATTCCCGA CGGGTTCTCAACAGCAT SQLE ADXCRPDRC.8241.C1_s_at TTTCCCGAGGTTGGGCTGTACAGTGTCTCCGTCCGCGGAAAAAGAAGCCTCTGAACCCGGGCC SEQ ID GGCCCGCAGCCCCCGTCGTTTCCGGCCGCTGCTCGCCGTCGCCCAGAGGCTAGGCCACGTTTT NO: CCCCCAGTGCCGAGGTGTTTCTGTGACCCCTCCCTCCACTCCCATTCCCTTCTGAAAGGGCAC 2031 CTGCTCTTGGTGAGAAAAGAAATTATAGCACGAAGAGCCAGTATCAGAAGAGTATCCATCACC CGCAGCAACCGCTCAGGGAACACCAT SQLE ADXCRAD_BU754109_at GTATAAGTCCCTGTACTTCAATGAAACTAATTCTTAAATTAAAATTTCTCAATTATTCCTGGC SEQ ID TCCCACAGACCAGAACATATGGATAAATCCATAGGCAAAAAACAAGCTTCTATTTTAATCAAG NO: GGTTATAGCTTCCTCTACCACCACCTTTAACTGCTGTTCCCTAGAAAGAAAACAGTACTAAAT 2783 ATTGCGTTTCTTCATTTCTTTGGGCCACCTTCTCATTGGGATACTAACAGATAATAAAATATC AAAATGTGTAAGGAAGAAAGATTTGCAGTAATTCCCTCGTGCC SQLE ADXCRAD_BF979497_at GCCCTTGGGACCTCACTTGTGGGAACCTTAACCCATCGAGACAGAAATCCGGTGACGGCGCCA SEQ ID AGAAGCTGGACCAGGGGCTTCGGCGTCGACCACACCTGTTAGAGCCGGACCATGGCCCGAGCC NO: GCGGCGGGGCCCCGGAGGCCACAGGCCAAGGCGGGCGAGGCAGCGCTCGAAAACACGGTGACC 2867 CCAAGAGGGAGAAGCCACTAGCGCAGAAGGGAA SUV420H1 ADXCRAG_BC002522_s_at GGGTGCTCTCTTCCACTACAGAGAATCCTGAAGAAAAGGGAAGGTGTTTCCCATGATGGTGAA SEQ ID TGTCACTGCCATGAATTCCTGAATCTACCTGCTGCTGGGAGTCAGAGTCCAAGCATAACCCGT NO: GTAGCATAAAAGCAGCGCTGTAGCCCTATTCCAGTCTTTTTCGTTAATGTCCAGAGTGAACAA 915 CAAGAGTTAGTCAATCATTAACTGTTGACTGTTGATTCTCATAA SUV420H1 RDCR087_E11_s_at CTTTATGTTCAATACCAGGTTCTTTTCATTTCTCTGGATTATTTTGCAAATCATTGGACAGAG SEQ ID AATTTGGGAATATAAATCTGTAACAGGTGTTTGACACCAGTAAGTCTCTTTATTTCTGGGAAA NO: TGTGTACCTGTACTTTCTGATATACAGTGTTCCTAAGTAAAAATCAATTCACGGGATTTGTAT 1362 AGTGTCTATAGGAAAGTAGCC SUV420H1 ADXCRPD.8158.C1_s_at GATGACAACAAGCAACATTTATCTAATGAACTACAGCTATCTTAATTTGGTTCTTCAAGTTTT SEQ ID CTGTTGCACTTGTAAAATGCTACAAGGAATATTAAAAAAATCTATTCCCTTTAACTTATAATA NO: GTTTATGAAATAAAAACATGAGTCCCAGCTTTTGTTCTGTGGTAACCTATAAAAAAAGTTTGT 1811 CTTTGAGATTCAATGTAAA SUV420H1 ADXCRSS.Hs#S2577958_at GTTCTTTATTACCAGCTTGAATGGGCAATGCCGCTAAAGATTTTAAGGCAGATTTAAGTAGTT SEQ ID TTCAATTTGAGTAATTTTTCTTGCTTTGGCTTTTCACAGGTAATGGTAACTCGGGATTTGAAG NO: GACAGAGTCGCTATGTACCATCCTCTGGAATGTCCGCCAAGGAACTCTGTGAAAATGATGACC 2132 TAGCAACCAGTTGGGTTCTTGATCCCTATTAGGTTTTCAAACACACAAAATGAATACTAGGTA ATTTTCAGTCTTTATCCTGAATGGAACAGA SUV420H1 ADXCRSS.Hs#S2577958_s_at ATGGTAACTCGGGATTTGAAGGACAGAGTCGCTATGTACCATCCTCTGGAATGTCCGCCAAGG SEQ ID AACTCTGTGAAAATGATGACCTAGCAACCAGTT NO: 2133 SUV420H1 ADXCRAD_BQ722638_at TGCAGCATAACGACCACACAAACCACCACANATATTGTCCCCCCCTTGCGCCCCCCCCCCTTC SEQ ID CTCCCCTTTCATCCCCGGTCCTTATCCACAACCCCCCCCGGGGGAACATGCTCTTCCAATAAT NO: CCCCTCCCCTCCTTACCCACGGGGGCCTAACAAGGTAAGGTGGCAAAATAACCTCCCCCGCCG 2350 CCCCCCTTTTATTTAAACACCCCTGTCCCGGCCGAAAACTCTGCCATGCGTGCCACCC SUV420H1 ADXCRAD_NM_017635_at AAAAGTCCAGTGGAGAAAATCTCAATGCTTACTGTTACTACTAATTGATTCCTACTAGTTTCC SEQ ID AGGTTTG NO: 2768 SUV420H1 ADXCRAD_NM_017635_x_at GGTGTTTGACACCAGTAGGTCTCTTTATTTCTGGGAAATGTGTACCTGTACTTTCTGATATAC SEQ ID AGTGTTCCTAAGTAAAAATCAATTCAGGGGATTTGTATAGTGTCTATAGGAAAGTAGCCCATG NO: TCTTGAAATATGAAAAGGAATCTGAAGGTCATGAAAAGTCCAGTGGAGAAAATCTCAATGCTT 2769 ACTGTTACTACTAATTGATTCCTACTAGTTTCCAGGTTTG TCF7L2 ADXCRAG_BC032656_s_at GTGCCATGTGGCTACATTAGTTGATGTTTATCGAGTTCATTGGTCAATATTTGACCCATTCTT SEQ ID ATTTCAATTTCTCCTTTTAAATATGTAGATGAGAGAAGAACCTCATGATTCTACCAAAATTTT NO: TATCAACAGCTGTTTAAAGTCTTTGTAGCGTTTAAAAAATATATATATATACATAACTGTTAT 955 GTAGTTCGGATAGCTTAGTTTTAA TCF7L2 ADXCRPD.1966.C1_at TTAAAGAGCCCTCCATCTTGCCTCTTGGCCGCTTCTTCCAAACTTTCCCGGGATTTGTCTCGG SEQ ID AAACTTTCGGAGCGAGGCGGAGGCCGTCTTTCCGCCTCGGAATCGGAGGAGCTGTTTTGATTC NO: GTTTCTGATTCATTGACTAGAGACGATTTGACATCAGCTAAATCCCTCTCTGCCGAGGAGTTT 1536 TCGGAGCTCTTCTCCTCCTGTTCGCCCTCGTCTTTGAAGGAAATCAGTTCGTCGTTGGCGC CTAGGTCA TCF7L2 ADXCRPD.16751.C1_at CGGTACTATACTTCTGTGCAGGCAGGTTCTGGTGTTGGGGACAAGGGTGTGAGTGAGAGGACT SEQ ID GAGTTGTTGCCTTTAGGAAGTGTACCGTCTAGCCAGGAGTAACGGCTTGAGTCGAAGTCGGCT NO: CCCATTGGGCCTCTTAGGGAGTCCCAGTTTGCTCTGAGGCCTGCTCCTCTCTGGGAAGAAATC 1852 ACCTTGAGAGCTTCTGGGATTTGGAACTCCCTGCATGGTTGGATCCCTTCCATCTTCATGTGA ATAGTCTTGGTAATGAGGCTGCCC TCF7L2 ADXCRSS.Hs#S11047314_at TTGCTCCTTGGGACAACTGAAGAATCCTTAGATAATTAATAGTATGAAATACTGCCCTTTTAG SEQ ID TTGAAAAATGTCACAATAATGTAATAAGATAAATAAGGAGGTGTCGCTTTAACCTGTATCGTG NO: TAGTCTCCTCTACTTACTAACACTTACTTGTATTACTAGAAGCATTATTTTTTAAATCATGGA 2081 AAATTGGTGGCAAGCTGAGCATACAGTTGTTTATTTCTGTTTGACTGATTATTACAACTTCAT TATTTGATGAAGGTTCTGTACGTTTTCCTTTAAGACACATA TCF7L2 ADXCRSS.Hs#S1920919_at TTTCAAGCAAACCACATCATTACCCACAGAGGCCATTGGTGAGATATTTGTAAGTCTCCTGAC SEQ ID AGTGGCTGGAGTTCGTTGCTTGGTAGTAGTTTCTCTGTCTCAGCCCTGGAGATGGGAGTGACC NO: ACCTGCTCTCTCTGGACAGAGGCTGTCCACGTTCATGCAATTCCTTGGACACCGGTGGCGCAG 2099 CGGGAGGCGTAACTGGGAGTGGGAGACCCTGAACTGTGCCGGTTCTTGCAGAGTATCAC TCF7L2 ADXCRSS.Hs#S3013361_at CGTCCTTTATGTGGCACACCCTTAAGGGAGACATCTTCCTGTCTGTGTATTGCACCCTCTTAA SEQ ID AACTACATTCCTTTCCCTTCAGCATTGGCATCTCTGTCCTTGTGTATTACCTGGGATGACTAT NO: TCAGTTAACAAATGCTTTCTTCCTAGGCTGTGAGCCCCAGTTTGTTGGATGATTGGATGGAGG 2171 CTATCAGCGC TCF7L2 ADXCRSS.Hs#S3742718_at TGTGAGTTGTACACCATGACTGGAATCGCTTGGACATACTCTTCAGCAGACATCGTGTGACTG SEQ ID TGGAAGAAATGAGTTTCATGAAGATGACTGATAGAAGGAAGCCACTGAACCAGTCCTCTATCT NO: CCTCTTCCAAGGCTAAAGTTTGGAGCCACTTGCAGAAGGCTCTCCTCAAACCCCTGTGTTCTT 2192 TGCCTACCCCTGCTGTTGCCACATCATCTTGGAGAGCTGGCTGC TCF7L2 ADXCRSS.Hs#S3891559_at GAGGGCGAGCACAATTTTACACAATTTACTGGCCAACTGTGGGCGAACAGTGCGGGGGCATAA SEQ ID GCGGGGTGGGATTTTTTGTGGGCGAATCTTGGGATGCGCCAGAGATGGGGGGACAATTTGAGT NO: GTCGGGGAAAATCTGTTTCCTTTTATTAATTTCATAGAGTATTGCCTTGGTCATTTGTCTATG 2219 AGAGATTTTCAATAATAGAGTGCTTGGCGAACACACATAATCTGGGGGGATGGCGATAAAGGA AAATTTAAAACATACTTCATTGCGGGCCGAGACT TCF7L2 ADXCRAD_AU118429_s_at AGAAGCCCCACATAAAGAAACCTCTTAATGCATTCATGTTGTATATGAAGGAAATGAGAGCAA SEQ ID AGGTCGTAGCTGAGTGCACGTTGAAAGAAAGCGCGGGCATCAACCAGATCCTTGGGCGGAGGT NO: GGCATGCACTGTCCAGAGAAGAGCAAGCGAAATACTACGAGCTGGCC 2539 TCF7L2 ADXCRAD_BU173366_s_at AATTCTGTATATTAGATTACTCTTAAACGAAAAACCAGCTGCCGCTTTTATGTACACATATTA SEQ ID CATACGAGTANGCAGCAGACTTTAAAAATAAAAAAACCTAGGCATGTTGATGTTGCAAAATGC NO: TGTATAAAGCTGAAACTGGTCATTCAGTGCCATTGTAGTTGACATGAAGCGATTGTAAAACTG 2575 TCTCCGATTTTTCTCTGGTT TCF7L2 ADXCRAD_AV758440_at GTATAAAGCTGAAACCTGTTCATTCAGTGCCATTGTAGTTGACATGAAGCGATTGTAAAACTG SEQ ID TCTCCGATTTTTCTCTGGTTTATTAAAATGCTAACTATAACATTTTTTGTGAATACTTTGAAT NO: GTTTCCTAACAGTTGTGATGTTACTGTTCCGTTTTATGCTCTTATTCCAAGTTCATTTTTAAT 2665 GGTTTGGAAGCCATTTTTGTAATGAATAAATGTTCATGCTGTACAGTATCTGTAGCATGCCGT TCTGGATTAATAA TCF7L2 ADXCRAD_AA664011_at AAATCGGAGACAGTTTTACAATCGCTTCATGTCAACTACAATGGCACTGAATGAACAGGTTTC SEQ ID AGCTTTATACAGCATTTTGCAACATCAACATGCCTAGGTTTTTTTTATTTTTAAAGTCTGCTG NO: CCTACTCGTATGTAATATGTGTACATAAAAGCGGCACGTGGTTTTTCGTTTAAGAGTAATCTA 2880 ATATACAGAATTTTGGCACGTAAAGTTTTGTACACGGTCAGTCCGGGTCCTAAGGGCGCAGGG TAGGGCATCCCACTGGGAGTTCAA TGFBR3 ADXCRAG_NM_003243_s_at AACTGTAGCAAGATGCAAATGCATGGCAAATCTGTCGGTCTCCAGTTGGTTATCTGAATAGTG SEQ ID TCACCAATTCCACCAAGACAGTGCTGAGATTGGAAAGGGCACTCATTTGGATTGCCTTACTTC NO: TCTTGCCTTAAATATATCCCATATATTTAATATGTCAAAAAGGGCTTGAGGTGAATTTCATTA 1021 AATGGAATAATATGATGCCACTTTGCAGCTAAAATAAGCTCAGTGATACCTCCTTGTT TGFBR3 ADXCRIH.3170.C1_at ATAAGGTATTTTCTCCCTAGCTTCTCATTTACAGTATTTCTAATTGCTTCACACTTTACAGTT SEQ ID TTAATACAAAGTACAAGCTCTACTTTTATAACGTGTACTACAAGTTTCTTTAAAAGAATGTTG NO: TATTTTCAGCTGACCTCTTGTATCTTGCATTCTTTGTTATTTTCTGCAGGCTACCCC 1206 TGFBR3 ADXCRSS.Hs#S624533_s_at AAGATTGATGTCTTAGAAGGACAGGGTTAAAACCTTCTGTAATATATTTAAATATATATTTTT SEQ ID AAGAGAGATGCTACATTGCCAATGATTTTATAAATAATTTAAAATTAATTTACAAATTTATAG NO: ATGCAAACCAAAAGATCTTTTTAAAAGAGAGAGAGAGGAAAAAAATCACCTTTTATTTGTTTG 2187 GGTCTCATTGTCAGAATTATTATTCAGATCAAGAAACCTGTGTCGATAAAACCTAATCTCATA TTGGAGAGTGAATGTCGTTAAGTATTTCTGAA TGFBR3 ADXCRAD_BF664880_at CCGGTAAGCACGACGCAACGAGCGACAGACACAGAGCCGACAGCAGACAGAAAGCGCAAAAGA SEQ ID GACAAGCGAAGACGGCAAACAACGCGGAGGAGAGACGGCACCAGCCCGAAGGCGAGAGCAAGC NO: GCACCAGCGACAGAAGAAGGAAAGCAAGAAACCACAAACAGACGAGCCAACAAAACAAAAAAG 2432 AAGAGACAACAACAGAGGAACGACACAGACAGAACCAGCACAGAAGAAACACAACAGAGAAAC AACGGGACCAA TGFBR3 ADXCRAD_BF677896_at ACAGTGGTGTGAAGAACCCCAGTAAGGTATTTACTTTCCACTGTACTCATATGTTTGGTTGAA SEQ ID CTCTTAACTCTATCCTTATTGGTTATTACTTGTTAATTCTGAGTTTCCCTTTATAAACTTTCC NO: TAAAAAAAAAAAAAAAAAAAATTGGGGGCGCGCGCAGAAAATTTAACACCATTG 2632 TGFBR3 ADXCRAD_BF677896_x_at TATGACTGTGAGACTTTTCCAAGGGATTTTTTTAAAAAACACATTAGGCTTTGTGCAGAAGTA SEQ ID AAGAAACAGTGGTGTGAAGAACCCCAGTAAGGTATTTACTTTCCACTGTACTCATATGTTTGG NO: TTGAACTCTTAACTCTATCCTTATTGGTTATTACTTGTTAATTCTGAGTTTCCCTTTATAAAC 2633 TTTCCTAAAAAAAAAAAAAAAAAAAATTGGGGGCGCGCGCAGAAAATTTAACACCATTG TGFBR3 ADXCRAD_AW268884_at GAAGTTGGATTCAGTCGTCCTGGCTCTGCCATTAGCCCATCCCTGGAGTTTAAAAAAGCAAGT SEQ ID CTTTTTAACTTCTTGGAGTTCAGTTTCCTCACCTGTGAAATGAAGAAGCTGAATAAGCTCATC NO: TTAGGGTTATTTGCTGCTCCAACAGTCTAATATTCTCTGAGGAACAATATGCTTGGGTTCATG 2838 GGAGAGTCACTTCCCACAGGAACCACGCTGACCAGAGCACCTGATTGCTAGCCTCTCTTCTCT GGA TGFBR3 ADXCRAD_BF439431_x_at GGTCTTATTCTGTCACTCAGACTGGAGTACAGTGGCATGATCATAGCTCACTGTGGCCTTGAA SEQ ID CTCTGGGGCTCAAGCAATCCTCTTGGTGGTTTTAAAAATTTTTGTAGAGACAGGAGTCTTGCT NO: ATATTCCCCAGGCTGGTCTTGAATTCCTGCCTCAAGCAATCTTCCTGCCTTGGCCTCCAAAAG 2895 CATCAGGATTACAGAAGTGAGCTATCATACCTGACTCAAATATTA TJP1 ADXCRAG_L14837_at TCTGTTAATCATTAGGTGTGACTGAATTTCTTTTGCCGTTATTAAAAATCTCAAATTTCTAAA SEQ ID TCTCCAAAATA NO: 993 TJP1 ADXCRAD_BM352913_s_at TTGAGCCTTGAACTTTGACCTCTGCAGCAATAAAGCAGCGTTTCTATGACACATGCAAGGTCA SEQ ID TTTTTTTTAAGAAAAAGGATGCACAGAGTTGTTACATTTTTAAGTGCTGCATTTAAAAGATAC NO: AGTTACTCAGAATTCTCTAGTTTGATTAAATTCTTGCAAAGTATCCCTACTGTAATTTGTGAT 994 ACAATGCTGTGCCCTAAAGTGTATTTTTTTACTAATAGACAATTTATTATGGCACATCAGCAC GATTTCTGTTTAGATAATACACCACTACATTCTGTTAAT TJP1 ADXCRIH.3943.C1_s_at AAGGTGAAACACTGCTGAGTCCTTTGGTGATGTGTGGTCCCCATGGCCTCAAGTTCCTGAAGC SEQ ID CTGTGGAGCTGCGCTTACCACACTGTGCGTCCATGACTCCTGACGGTGATCCTAAAACCTGGC NO: AAAACAAGTGTCTTCCCGGAGATCCAAATTATCTCGTTGGAGCAAACTGTGTTTCTGTCCTTA 1240 TTGACCACTTTTAACTCTTGAAATATAGGA TJP1 ADXCRPD.11593.C1_at TGGGCTTCCGGTCTGAGTCTACCATGTGTGTCATACCCAGGAGCTGGCTGCTCTTCGTGCCGC SEQ ID AGGGCGGATGCTCTAGGTGCCTGTTCGTAACGTGGTCTGCTGTCGTAAGACAGAGGGGCTGGC NO: TCTTCAAAACGTGGAAAGTACCCTCGTTCTGAGGACTCTTCGGGATGCTGTCTGGAGTCAAGG 1531 TCTTGAGAGTGCTGATTATCAAAAGGTGGCCGAGATGGGTAGGGCTGTTTGTCATCATAATAT GACCACTGTTCTTCATACATGGG TJP1 ADXCRPD.14975.C1_s_at TTAAATGCACCTGGAATATATAACCAGTGTTGTGGATTTAACAGAAATGTACAGCAAGGAGAT SEQ ID TTACAACTGGGGGAGGGTGAAGTGAAGACAATGACTTACTGTACATGAAAACACATTTTTCTT NO: AGGGAAGGATACAAAAGCATGTGAGACTGGTTCCATGGCCTCTTCAGATCTCTAACTTCACCA 1769 TATTACCACAGACATACTAACCAGCAGAAATGCCTTACCCTCATGTTCTTAATTCTTAGCTCA TTCTCCTTGTGTTACTAAGTTTTTATGGCTTTTGTGCATTATCTAGAT TJP1 ADXCRPDRC.11593.C1_s_at AGATCTGCATCCTTAGAGACCAAGAAGGATGTAAATGACACTGGCAGTTTTAAGCCTCCAGAA SEQ ID GTAGCATCTAAACCTTCAGGTGCTCCCATCATTGGTCCCAAACCCACTTCTCAGAATCAATTC NO: AGTGAACATGACAAAACTCTGTACAGGATCCCAGAACCTCAAAAACCTCAACTGAAGCC 1959 ACCTGA TJP1 ADXCRSS.Hs#S2984021_at TAGTTCAAAGCAACCCATCGTTCTTGCTTACATCTGCATTTCAAACCAGCTTTAAAAACTTAA SEQ ID GTGGATTGATTAGTTCTAAGTTATTCTTGCCCAGACTTTCATATATTTCCTTGACTGGCTACT NO: GGATTATAGTATTCCGAACCCTGGCCAGCTTAAGATTAGAGTAGATAGCAAGAAGACTTTTCT 2152 TCTGCAACAGCTGTTACCGAGTTTAGAAGCCCTTTAGACTTGTTCCGAGGGATTGTGCTCTTA CAGGATAGATCCCTGGATTCCCACTC TJP1 ADXCRAD_BM674772_at TCTGCCTCTACTAAATGGCTCCAAACAGCTGCAATTTCACAACCAAAGTTTTTTACTTGAAAC SEQ ID AGCATGTTACTCCTTGCTAATCTAATTGAGTGTGTATTAATCGGCTACACTGGTCACACATTT NO: GATTGGGTAAGACCTAAAGTAGGCTCTGCTTAACAGTGAGTCCGTTCATGTGACCTATAAAAT 2599 CTCTCTCAGAGACTCCTTTCCAGTCCATCTTTGTCAGCTGTCTTGTCTAGAGCTTTCAACTAG CTCATAGCCTCCAGATAACAAGGTCCTCGTGCCGAA TJP1 ADXCRAD_BM674772_s_at ATTGAGTGTGTATTAATCGGCTACACTGGTCACACATTTGATTGGGTAAGACCTAAAGTAGGC SEQ ID TCTGCTTAACAGTGAGTCCGTTCATGTGACCTATAAAATCTCTCTCAGAGACTCCTTTCCAGT NO: CCATCTTTGTCAGCTGTCTTGTCTAGAGCTTTCAACT 2600 TJP1 ADXCRAD_CN372474_at TGACTCCTGACGGTTGGTCTTTTGCTCTAAAATCATCCGACTCCTCGTCGGGTGATCCTAA SEQ ID AA NO: 2668 TJP1 ADXCRAD_AL109707_at ATTACCGATGGTTGATGGACATGCCAAGGTATTGACCTCTTAAGCCAGTAGTGGCTGGTTAGA SEQ ID GCTTGGCAAAGGAGCAGCCCCCTCAGTTTATCTCAGTGTGCCATACAAATAATATTTTCTCTG NO: GATGTTACAGTGTGAAAAAGGGTGGGAAGTAGTGCCCTGTTGAGCCATATTAGAGCCCCAGGC 2830 AAAAGAAA TJP1 ADXCRAD_AW173166_at GGGTAAACAACTATCTGATGTACATATTCAACTGTCACTGAGGACCAGTAGAGAGATCAGAAT SEQ ID CCATGAGGAGGCAAATTCTGCCTGTTTTTTTCTGATATAATTCCAGGGCCCACAAGAGTACAA NO: CAGTGCTTGGCATACAGTAGAACACTAAAAAATTACTTAGTCTTTAAGAATGAATAGGGTTTC 2897 AATGGTTTCTAGAAATATAAGATGAAGAAAATATCTTCTGGAAATACAAATGAAAGAATGAAG CATATATTATTCTAGACAGTAAA TMEM97 ADXCRAG_BC045655_s_at CTACAGCCAGGCATAACATATCCACTGTGTGCATAGAGGGTCTCTTCACGTTGATGCTTGGCA SEQ ID TTCCATCAGCTTTCTCTAAGTCTTTGCTCAAGTTCAACCTTAAAATGATGTTAG NO: 966 TMEM97 ADXCRAD_CX867137_s_at TTAATTTTCATGTTGCGGAGCCCCTACTACAAGTATGAAGAGAAAAGAAAAAAAAAATGAAGG SEQ ID AAACAACCACTGGCCCAGGGTAGAGATGCCTACAGGGTGGTTGCTTGTTGGATACAATACAAG NO: GAACACTGCTCAGAACCCACGTCTTCAGCAGCATTTGAAACACTGGCAGCAATGCACAAGAGC 2532 AAGATGGTGTCAGGAACCATGTCAAACCCTC TMEM97 ADXCRAD_BU857068_at TCTTCCTGCCAAGAAAGAATGGGGGATTCCATTCCTTGAGGGATTATGCCAAATTAACAAGAA SEQ ID TCTCGGGGGAAACACAGGATAAAT NO: 2566

TABLE 11 Genes and corresponding Almac probesets predicting sensitivity to oxaliplatin. There can be multiple Almac IDs/probesets associated with a given gene. Almac SEQ ID Gene Probe ID Probe Sequence NO HNRNPA1 200016_x_at AACTCGAGGACTGTATTTGTGACTAATTGTATAACAGGTTATTTTAGTTTCTGTTCTGTGGA SEQ ID AAGTGTAAAGCATTCCAACAAAGGGTTTTAATGTAGATTTTTTTTTTTGCACCCCATGCTGT NO: TGATTGCTAAATGTAACAGTCTGATCGTGACGCTGAATAAATGTCTTTTTTTTAATGTGCTG 830 TGTAAAGTTAGTCTACTCTTAAGCCATCTTGGTAAATTTCCCCAACAGTGTGAAGTTAGAAT TCCTTCAGGGTGATGCCAGGTTCTATTTGGAATTTATATACAACCTGCTTGGGTGGAGAAGC CATTGTCTTCGGAAACCTTGGTGTAGTTGAACTGATAGTTACTGTTGTGACCTGAAGTTCAC CATTAAAAGGGATTACCCAAGCAAAATCATGGAATGGTTATAAAAGTGATTGTTGGCACATC CTATGCAATATATCTAAATTGAATAATGGTACCAGATAAAATTATAGATGGGAATGAAGCTT GTGTATCCATTATCATGT RPL10A 200036_s_at CAGCTTGAAGAACTATGATCCCCAGAAGGACAAGCGCTTCTCGGGCACCGTCAGGCTTAAGT SEQ ID CCACTCCCCGCCCTAAGTTCTCTGTGTGTGTCCTGGGGGACCAGCAGCACTGTGACGAGGCT NO: AAGGCCGTGGATATCCCCCACATGGACATCGAGGCGCTGAAAAAACTCAACAAGAATAAAAA 831 ACTGGTCAAGAAGCTGGTCAAGAAGTATGATGCGTTTTTGGCCTCAGAGTCTCTGATCAAGC AGATTCCACGAATCCTCGGCCCAGGTTTAAATAAGGCAGGAAAGTTCCCTTCCCTGCTCACA CACAACGAAAACAT RNPS1 200060_s_at CAGGGAAAAGTGAGGCTCTTGGGGGTGGTTTGACCCTGCTTACCTGGGAGCACACTTTTCCC SEQ ID TTCCCCGATGACCTGGGATGGTGGCCAGGCCGTGCCCTTGCTGTTGCTGGGCAGTGTCCTTT NO: TGGAAAGGGAGCTGCCCCAGGCTTTAGTGCAGCTGCCAACCCTGTTAGGCCTGGCCTCTCGA 832 GGCCTCTTCTGATCTCAAGGGTCACACCCCCTCAAAGATCCTCTCACCCATGGTAGTTGCTG CTCGTGGTTCTGTCTGTCCGTGCACCGATGCACACACCGCACCCCACCACTGTACTCTGAAA TTGGCGAGTGAGTGGAGAGCCAGCTCTGCGGAGTCATCACGCAGCCATGGTTGTGCCTGCCG TTCATGGTGGTCTTTCAGGTTATCTTGGCAACATGTACATTGCTTTTATTTTTTTTCTTTTT TGCTTTCATTGTACAGTCAGTACTATAAAATTTCTCTTTTGAGTTTTATACCTTTGTAGCAT TTTAGATGACATTGTGTTTGTACTTTGTTG RPS6 200081_s_at ACTTCGTACTTTCTATGAGAAGCGTATGGCCACAGAAGTTGCTGCTGACGCTCTGGGTGAAG SEQ ID AATGGAAGGGTTATGTGGTCCGAATCAGTGGTGGGAACGACAAACAAGGTTTCCCCATGAAG NO: CAGGGTGTCTTGACCCATGGCCGTGTCCGCCTGCTACTGAGTAAGGGGCATTCCTGTTACAG 834 ACCAAGGAGAACTGGAGAAAGAAAGAGAAAATCAGTTCGTGGTTGCATTGTGGATGCAAATC TGAGCGTTCTCAACTTGGTTATTGTAAAAAAAGGAGAGAAGGATATTCCTGGACTGACTGAT ACTACAGTGCCTCGCCGCCTGGGCCCCAAAAGAGCTAGCAGAATCCGCAAACTTTTCAATCT CTCTAAAGAAGATGATGTCCGCCAGTATGTTGTAAGAAAGCCCTTAAATAAAGAAGGTAAGA AACCTAGGACCAAAGCACCCAAGATTCAGCGTCTTGTT MDN1 ADXCRAG_AB002299_at CTGTTGTTGATGTAATTTGTGACTCTTCTTAATGGAAGATGACAGGATTGTAAAAGGTATGC SEQ ID TAGGGGACTGATCTTCTCTGCTGGATCAGTCAGTCAGCTGTTACTAGTTGATGCTGTGCTAA NO: CATGATCCCCTCCTACTTCCATGTTGCTCTTACTACAAAGGTTATCATTTGCATTTATGTCC 835 ATGGTAGGCTGAGCTATAATATGCTGGCTTTGCAGCAGAATGAAAAGGATGAGTTGGTGTAG CCTTATAAG MRPS2 ADXCRAD_AL583494_s_at TTGGCTGCAGTTAGGACCTCAGTGGCTGGTATGGCCGAGCTGCTAGAAGATGCTGCTGTCCC SEQ ID TGTGATCCCAGCAGCCCTCCCTTCACCGTGACCCCTGACCTTTGTCAGGAAGGTGCAGTTTT NO: TCTTCTCAATCTAAATGCCTTTCAGGTGGGCCGCTTCCTTGGCTACCTGGTTCCAGGGGGCT 839 GTTTTGTAATGAGATGCTGCTGGCAGGCCACTCAGAGGCTCCCAGCTGGGTTGGTGGGACAG CCAGGCCAGATGACCTGATTCCAGCAAAAATAA ABCA7 ADXCRAG_AB055390_s_at CCCTGGCGCGCGTCTTTGGAGAGCTGGCGGTGCACGGCGCAGAGCACGGCGTGGAGGACTTT SEQ ID TCCGTGAGCCAGACGATGCTGGAGGAGGTATTCTTGTACTTCTCCAAGGACCAGGGGAAGGA NO: CGAGGACACCGAAGAGCAGAAGGAGGCAGGAGTGGGAGTGGACCCCGCGCCAGGCCTGCAGC 840 ACCCCAAACGCGTCAGCCAGTTCCTCGATGACCCTAGCACTGCCGAGACTGTGCTCTGA ATP2A3 ADXCRAG_AF068220_at TGTCCCGGAACCACATGCACGAAATGAGCCAGAAGTGAGCGCTGGGAACAGAGTGGAGTCTC SEQ ID CGGTGTGTACCTCAGACTGATGGTGCCCATGTG NO: 849 ATP2A3 ADXCRAD_BX437326_s_at GACTGTGAGGTGTTCGAGTCACGCTTCCCCACCACCATGGCCTTGTCCGTGCTCGTGACCAT SEQ ID TGAAATGTGCAATGCCCTCAACAGCGTCTCGGAGAACCAGTCGCTGCTGCGGATGCCGCCCT NO: GGATGAACCCCTGGCTGCTGGTGGCTGTGGCCATGTCCATGGCCCTGCACTTCCTCATCCTG 850 CTCGTGCCGCCCCTGCCTCTCATTTTCCAGGTGACCCCACTGAGCGGGCGCCAGTGGGTGGT GGTGCTCCAGATATCTCTGCCTGT PDSS1 ADXCRAD_BM824056_s_at AACTTCGACCATCCCCAGAAAGAGATGCCCTCATTCAGCTTTCAGAAATTGTACTCACAAGA SEQ ID GATAAATGACAACTCTTTCTGTTCTTTCTGGCAGCTATCTTACCAGACTGTGCCTAAAGAAT NO: TTTGTGGAATACACTTTGTTTGCTTCATGTGCAGATAACCAAAAATCATTTTAAAAGATATC 862 AAACTTATTGATGGGCAAT CYFIP2 ADXCRAG_AF132197_s_at TGGGAATTTTTGTACAATGAATTTACATTTATTTATGGTGACATATTTACGCTTGTGATCAA SEQ ID ATAATGATGTTAAATTCTTAAATCATATTTGCTATGCAGCTGAAGATGATATTTTGA NO: 863 CYFIP2 ADXCRAG_AF132197_x_at TTTCAGAAACTGTCAAATGTACCATATTTGTATTAAGAGTTGTTGGGAATTTTTGTACAATG SEQ ID AATTTACATTTATTTATGGTGACATATTTACGCTTGTGATCAAATAATGATGTTAAATTCTT NO: AAATCATATTTGCTATGCAGCTGAAGATGATATTTTGATTTGTATTTTGGGGGTACCTGTGT 864 TGAGTTGATAAACATTTCCATCTTCATTAAAACTGCTTCCAAACTAAA BIN2 ADXCRAG_AF146531_s_at CTCAGGGAATATTTAATTCTGGTTTTAGCATTATTAGAATAAGACTTTATACATTAACTAAA SEQ ID GTGGAGCTTTAATCACTATAAAAAGCAAAAGTATNTATAGACACAGACACTTGCCTATACAG NO: AGACATAACCACACACACTCAGAGGATAGTGAACAAATCTGTCTTTGACTTACGACCCATTT 867 TGCAAGAC MDN1 ADXCRAG_AF503925_s_at AGCAGGTGCCTGAACTCGTAACTAGAGAAGAGTTATCCTTCTTCCCTGCCTTGGAAGCCCTG SEQ ID GCCTGGGAGGAGGTCATACCCCACCGTTGGAGCCCAGCTGCCTGTTTTCTTTTGCAGGGGAT NO: CTGGGCACCTGTGCCTTGAGGAGATGCTGCCAGGAGCATGGGACTCTGACAGTCCTTTGTAT 879 AAAGGACTAAAGGGAGCTGCCCTTTTGACCCTGTTCTAAGCTCTGCCTTGCCAAGCCCATAG TGTGTGCCCAAAAGCTGTCAAGTGGCCAAGACAGCTCGTTTCTGGAG HSPD1 ADXCRAG_AJ250915_at TTTGTACATTCCTGATACTGGGTACAAGAGCCATGTACCAGTGTACTGCTTTCAACTTAAAT SEQ ID CACTGAGGCATTTTTACTACTATTCTGTTAAAATCAGGATTTTAGTGCTTGCCACCACCAGA NO: TGAGAAGTTAAGCAGCCTTTCTGTGGAGAGTGAGAATAATTGTGTACAAAGTAGAGAAGTAT 881 CCAATTATGTGACAACCTTTGTGTAA BCL11A ADXCRAG_AJ404611_s_at AAGCTGTTTGTCGTAACTTGAAATTTTATCTTTTACTATGGGAGTCACTATTTATTATTGCT SEQ ID TATGTGCCCTGTTCAAAACAGAGGCACTTAATTTGATCTTTTATTTTTCTTTGTTTTTATTT NO: TTTTTTTTATTTAGATGACCAAAGGTCATTACAACCTGGCTTTTTATTGTATTTGTTTCTGG 882 TCTTTGTTAAGTTCTATTGGAAAAACCACTGTCTGTGTTTTTTTGGCAGTTGTCTGCATTAA CCTGTTCAT BCL11A ADXCRAG_AJ404613_s_at CTTTCTGGCCCAGTTAATTTGCACAGAACTTTTCTCAGTTTGGTATTTTTTACTGCTTGGAG SEQ ID ATCCAGAAGAGAATTAGAAACAACATAGCAAATTAAAATAGGTTTGTCAATAATAGAGCTCA NO: GACACCTGTGTGCTGTAGATTCACATACAGGCCGTGAACCTAAGTGGGGAAAATCCTACCTA 883 TCCACCTTCTGGCTAGATTACCTAGCTTAGTGAAAAG BCL11B ADXCRAG_AJ404614_s_at TTATTATTGCTTGGTATTTGTGCTCTGTTTAAGAAACAGGCACTTTTTTTTATTATGGATAA SEQ ID AATGTTGAGATGACAGGAGGTCATTTCAATATGGCTTAGTAAAATATTTATTGTTCCTTTAT NO: TCTCTGTACAAGATTTTGGGCCTCTTTTTTTCCTTAATGTCACAATGTTGAGTTCAGCATGT 884 GTCTGCCATTTCATTTGTACGCTTGTTCAAAACCAAGTTTGTTCTGGTTTCAAGTTATAAAA ATAAATTGGACATTTAACTTGATCTCC NUP210 ADXCRAG_AK074101_s_at ACGTGTGATCCCTTTCACTCCATCAGGACACCAGGACTGTCCTTAGGAAAATGTCCTTGAGA SEQ ID TGGCAGCAGGAGTCATATTTTCTGTGTGTGTGTTTCGGAAAGCCGCTGTGTCCTGCCTCAGC NO: ACAAAGACCCAGTGTCATTTGCTCCTCCTGTTCCTGTGCCACTCCAGAACCTCAGCAGATCT 885 GAGCCACCGCCTGCCAGTGTGAGAGGCGGCCACTTTCATGGCAGCT HMGB1 ADXCRAG_AL110194_s_at AAATCTATAATTAATTGGGCCAACTTTTAAAATGAAGATGCTTTTTAAAACTAATGAACTAA SEQ ID GATGTATAAATCTTAGTTTTTTTGTATTTTAAAGATAGGCATATGGCATATTGATTAACGAG NO: TCAAATTTCCTAACTTTGCTGTGCAAAGGTTGAGAGCTATTGCTGATTAGTTACCACAGTTC 888 TGATGATCGTCCCATCACAGTGTTGTTAATGTTTGCTG PAICS ADXCRAG_AL833068_x_at AATTAGCTGGGCGTGATGACAGGCACCTGTAATCTCAGCTACTCGGGAGGCTGAGACAGGAG SEQ ID AATTGCCTGAACCCGGGGGGTGGAGGTTGCAGTGAGCCAAGATCATGCCACTGCACTCCAGC NO: CTGGGCAACAGAACGGAACTCTGTCTCAAATAAA 897 CHD7 ADXCRAG_AL833190_at CAGTTCAGCAAGCTAACATAATAATAAAAACAAGTTTTGCTGTCATTAAGTTTTATCATTGA SEQ ID GCTGTTAGGAGGGAAGAACTACTTAGGTATTTCCATTTGGAATGGCAGGTTCACCACAGAGG NO: CTCACATTGAGATCAAGTTGTCTTCGACAGCCTTTATAGCCACTGTTTGCCTC 898 41888 ADXCRAG_AY034177_s_at ACACGTACACACATCCCTCACTTCTCTTAAGCCAAGAAGTTTGCTTTCCCTAGCTGCAGTGT SEQ ID AGATGGCTCTTGTTTTTGTTTTTTTGTTTTAATCATTTGGCATTCACATGTGGCTGTTAATA NO: TGTGCTTGTTTTT 901 USP7 ADXCRAG_AY376241_s_at CCCCAAAGAGGAGTCGCTACACTTACCTTGAAAAGGCCATTAAAATCCATAACTGATTTCCA SEQ ID AGCTGGTGTGTTCAAGGCGAGGACGGTGTGTGGGTGGCCCCTTAACAGCCTAGAACTTTGGT NO: GCACGTGCCCTCTAGCCGAAGTCTTCAGCAAGAGGATTCGCTGCTGGTGTTAATTTTATTTT 908 ATTGAGGCTGTTCAGTTTGGCTTCTCTGTATCTATTGACTGCCCTTTTTGAG TRIAP1 ADXCRAD_BU539578_s_at TTCAGAGCTCTCAGTGTGCAGTTCAGGAATTAAGATACTTGGAATAGCTGTGGAGGAAGAAC SEQ ID CTAAATTGCAAAGATCTGCTATTGCCAGCTCTCAACCCAAGTCAGTGAATTGTCAACCTGCA NO: TATCCTAAAAATGTCAAAATGCTGCATCTGGTTAAATGTCGGGGTAGGGGGGAAGCTGAAGG 916 TGCTCGCTTCATTTGCCTTGTTTACTCATCCTGCCCTGTAATGTCTGTAATCCTGAA RUVBL1 ADXCRAD_CN389613_s_at AAGAGCATGTCGAAGAGATCAGTGAACTTTTCTATGATGCCAAGTCCTCCGCCAAAATCCTG SEQ ID GCTGACCAGCAGGATAAGTACATGAAGTGAGATGGCTGAGGTTTTCAGCAGCAAGAGACTCC NO: CCAGGTGTGCCTGGCCTGGGTCCAGCCTGTGGGCGCTTGCCCCTGGGCTTGGGGCTGCCGTC 918 CCCACTCAGGCGTGGGCTGCAGCGCTGTCAGTTCAGTGTGGAAAGCATTTCTTTTTAAGTTA TCGTAACTGTTCCTGTGGTTGCTTTGAAAGAACCCTTC IMPDH2 ADXCRAG_BC006124_at AGTGTCTGGTGCTGTGCAGGACAAAGGGTCAATCCACAAATTTGTCCCTTACCTGATTGCTG SEQ ID GCATCCAACACTCATGCCAGGACATTGGTGCCAAGAGCTTGACCCAAGTCCGAGCCATGATG NO: TACTCTGGGGAGCTTAAGTTTGAGAAGAGAACGTCCTCAGCCCAGGTGGAAGGTGGCGTCCA 921 TAGCCTCCATTCGTATGAGAAGCGGCTTTTCTGAAAAGGGATCCAGCACACCTCCT TRIM14 ADXCRAG_NM_033219_s_at TGGACTACGAGGCCGGCGTCCTCGCCTTCTACGACGTGACGGGCGGCATGAGCCACCTGCAT SEQ ID ACCTTCCGCGCCACGTTCCAGGAGCCGCTCTACCCGGCCCTGCGGCTCTGGGAGGGGGCCAT NO: CAGCATCCCCCGGCTGCCCTAGGGGCCAGGACCGGCGTGACAGCCTCCAGA 922 LCP1 ADXCRAG_BC007673_s_at TGTAATGGAACTTAGCCATTTTTCAAAGCAATTGAAATGCATTGCTCTGGATCTGTTCCTTG SEQ ID GCAGTGGACTCAGAAAGCCAACATGTGGCTCCTCCCAGCCCATAACCAGTATTTTTGCTGCT NO: TCTGAATACAAATTGGTTGGTTTTGACTTCAGATTGAACTTACTGTAGCCTCAGATGATTTC 924 CCCCCTCCGCCTCCAGGAAGAAAGAATGTTACTGCCTTAATAAA EZH2 ADXCRAG_BC010858_s_at AAATGGAAATCCCTTGACATCTGCTACCTCCTCCCCCCTCCTCTGAAACAGCTGCCTTAGCT SEQ ID TCAGGAACCTCGAGTACTGTGGGCAATTTAGAAAAAGAACATGCAGTTTGAAATTCTGAATT NO: TGCAAAGTACTGTAAGAATAATTTATAGTAATGAGTTTAAAAATCAACTTTTTATTGCCTTC 929 TCACCAGCTGCAAAGTGTTTTGTACCAGTGAATTTTTGCAATAATG CYFIP2 ADXCRAG_BC011762_s_at AGACAGACAGTTCCACTGTGGAGCATGTGCGCTGCTTCCAGCCACCCATCCACCAGTCCTTG SEQ ID GCCACCACTTGCTAAGCAGAAGATCCTGCAGACCCTTATCTGGAGGAGGAAGAGAAGCAGGA NO: GAGAGAAAGCCACAGCCAGCCTGCCATAGGATCCAACTGGACAACGTGTGGGATGGACCTGG 932 AAACAAGCACCTCCCCAAACACATCACCACTCCCTAGGGCGGGGCCTGTGCATGCTCTCCCA TGACATCTCCATGCTGGTTTCTCCATAGCATAAATG PCCB ADXCRAG_BC017735_at GTACAATTTGAAACTGATGCTTCACCTTTCCTTTAA SEQ ID NO: 941 PCCB ADXCRAD_CB163512_s_at TTTCTCCCAGAATTGTGGGCTTCACTGGAAGTGAAGGTGCAGGAATGACTGGACTGTCCACC SEQ ID CCAGCCCTGCCTGCCTGTGGTTTTGGCCAGGGAGCAAGCCATGAGGTGCCCTGGCACATGCA NO: CAAATTGATCCTTTGCGTGACAGTCTTGTATGGAAAACAGATGCTGACAGAATTGTAGACTA 942 CCATGCCACACAAAAAGGCTAAATATCTACTCCAATGGGTTTCCAGTTCAGTTTGAAGTCAA TCAAATTTTTGTATTTTTCGGTGTCTCCTTGATTGGTTTTGCTA PCCB ADXCRAG_BC018013_at CTCGAGTTAGTTTTTTTATCCATAGGTGAGATATATAGTAAGTTTTTAAGGCAAAGTATTTC SEQ ID TTAGGCTTAAGTTTCCTTATTTTAAAAATAGGGTAATATGCCCTATCTATCTCCTAATTCCT NO: CCATGAATTGAGGATTAAATGTGATGTTTGCAATTGTGGTATATGTGTTTAGCAGTACAGAT 944 GCTCAATAAGGCATAGCACCCTATGTTGACTCAGGTTATTTCCAGAA IKZF1 ADXCRAG_BC018349_s_at GGGTTCTTAGTCTCAGCACTATGACATTTTGGGCTGACTACTTATTTGTTAGGCAGGAGCTC SEQ ID TCCTGTGCATTGTAGGATAATTAGCAGTATCCCTGGTGGCTACCCAATAGACGCCAGTAGCA NO: CCCCGAATTGACAACCCAAACTCTCCAGACATCACCAACTGTCCCCTGCGAGGAGAAATCAC 945 TCCTGGGGGAGAACCACTGACCCAAATGAATT BCL11A ADXCRPDRC.960.C1_s_at CATTCGGCGTAGTACCCAGAGAGCTCAAGATGTGTGGCAGTTTTCGGATGGAAGCTCGAGAG SEQ ID CCCTTAAGTTCTGAGAAAATTTGAAGCCCCCAGGGGTGGGGTGGACGGTGCCGCCCAGTCGA NO: CGTCAGCGTGGTCTGTCATCCTGCTAGTTTGTGATGTTTTCTGACAGTAGCCTCCAAGAAGC 947 CGTTGTGCGAAGACAGAGTCCTGCAGAGTCCTTCCAGCCTAGGCCTGCAGCGCCATTTTA CD3D ADXCRAG_BC039035_at AAAAATAGATGTTGGGTCTCGTCAAGTGCTTACCCTGCATCCATTGAGATGATAATATGGTT SEQ ID TTACTTTTTTAGTCTGTTAATATGGTACATTACATTGATGGCACGATATGTTAAACCAACCT NO: 959 CD3D ADXCRAG_BC039035_x_at AGTTCTTTTCTTTCTAGTTTGCTGAGAATTTTTATCAAAAATAGATGTTGGGTCTCGTCAAG SEQ ID TGCTTACCCTGCATCCATTGAGATGATAATATGGTTTTACTTTTTTAGTCTGTTAATATGGT NO: ACATTACATTGATGGCACGATATGTTAAACCAACCTTTCATTCCTGAAAAAAACTCTAGTCA 960 TTTGGTATTATTCT RNF44 ADXCRAG_BC039833_at AATATTGTTGCTGATTTCAGAGGGATATTCACTAATAAATGTAT SEQ ID NO: 962 RNF44 ADXCRAG_BC039833_s_at TTTCCATTCCATGGGATTCACATTGGTTTGTAGCATTTAACATAACTAGTATGTTGTATTAT SEQ ID ATATATGTGTATACTGATTGAAATTTTTAACAGATTTGTACTTTTTTTAAAATGAAAGTTGC NO: TAGTTCTGCTTGACCAAGTAGTG 963 SKAP1 ADXCRAD_CR741870_s_at CCAAGTCTCTTGACACCTCAGAGTGACTGTAAGCTACCAGTAAGACAAGTGGGAAGAGGCAC SEQ ID GTTCATCAAACCTGTTACTAAACCAGCCTAGTCATAGCTCATCCCCATCTCTAAATGTGTCC NO: ACACAACCACATCTGCCTTTTCCACAAGCTTTTCACAAAGAAGGTGAGAGAGAAGGAAACCT 969 TGGGAGGAGGACATTACTGGTTGTTCTGGCTGGTTTGAA NASP ADXCRAD_CX783596_s_at GATATTTCCCACCTTGTCAGAAAGAAGAGGAAACCAGAGGAAGAGAGTCCCCGGAAAGATGA SEQ ID TGCAAAGAAAGCCAAACAAGAGCCGGAGGTGAACGGAGGCAGTGGGGATGCTGTCCCCAGTG NO: GAAATGAAGTTTCGGAAAACATGGAGGAGGAGGCTGAGAATCAGGCTGAAAGCCGGGCAGCA 972 GTGGAGGGGACAGTGGAGGCTGGAGCTACAGTTGAAAGCACTGCATGTTAA NUP210 ADXCRAG_BC067089_s_at GTGTCGCCATGGTAAGCTTGGGCCATCGGTCCCCACTGTTGGTTTTCATTCCTTATCTGGGC SEQ ID TGTTGTGTGGTTAATTGATTGATCATTTTGAAAGCTAGCACTTGACTCACACTCGGAATCCC NO: AGAA 976 HNRNPA2B1 ADXCRAG_BX537494_s_at GAATGTGATACTCAGGGCTTACTCTATACACCAATGAGTCTTCTTTGATCCTAAGACCACCA SEQ ID CTGAAGTTGTTTAGGTTCTTTTGGACAAACATGATAAACTTCTTCAGA NO: 978 PAICS ADXCRAG_BX538303_at TAGGCACAAAATTTAATTCTCAGAGCCTATAAAAACAGTAAAGGAAATAGGCATGAACACAC SEQ ID AAGGCCAGATAACAGCAGTAACATTTTGGCAACTGAAAGGCAAACACAGTGGTAGCTAAGTT NO: AGCAGACCAAGAAAACTTAATC 980 PAICS ADXCRAG_BX538303_x_at TAGGCACAAAATTTAATTCTCAGAGCCTATAAAAACAGTAAAGGAAATAGGCATGAACACAC SEQ ID AAGGCCAGATAACAGCAGTAACATTTTGGCAACTGAAAGGCAAACACAGTGGTAGCTAAGTT NO: AGCAGACCAAGAAAACTTAATCAAAATTAGCTGGCATGG 981 THUMPD1 ADXCRAG_BX640898_at TGCAGTCTTATGGTTTAGAAAACTTGTTTAGCTCCATAGAGGAAAGAATGTTAAACTTTGTA SEQ ID TTTTAAAACATGATTCTCTGAGGTTAAACTTGGTTTTCAAATGTTATTTTTACTTGTATTTT NO: GCTTTTGGTACGGCCAGAAATCGAGCTTGTTTTTTCATAGTTCCTGATATTTTCAGAA 982 TRAF3IP3 ADXCRAD_NM_025228_s_at CCTCCCAGAAGGCAATGTGGGCGATGGCTCCCAGTGCTGATGGTGGTGATTGCTGCAGCACT SEQ ID GGCAGTGTTCCTGGCCAATAAAGACAACCTGATGATCTGAATAATTTGTGACAACTGCCTTG NO: GGTGAAAATCAGAAGCAAGCAACTCAGCGAAAAACTCAGAAGGTTTGGGTACATTACAGCTT 985 GGGTTTTCCAACTGACTTAGGATTTCTGACTTTTTATTAATTTCTTAACCTACTGTAAATAA ACTTCACCTGACCAGATTGTTCCT HNRNPA2B1 ADXCRAG_D28877_s_at TCTTTGTAAGAGTGTAGAAGCATTCCTTCTTTGATAATGTTAAATTTGTAAGTTTCAGGTGA SEQ ID CATGTGAAACCTTTTTTAAGATTTTTCTCAAAGTTTTGAAAAGCTATTAGCCAGGATCATGG NO: TGTAATAAGACATAACGTTTTTCCTTTAAAAAAATTTAAGTGCGTGTGTAGAGTTAAGAAGC 987 TGTTGTACATT MX2 ADXCRAD_AJ711736_s_at AAATTCTTCTTTTGTATGTCCAGTCTCCTGCACAGCACCTGCAGCATTGTAACTGCTTAATA SEQ ID AATGACATCTCACTGAACGAATGAGTGCTGTGTAAGTGATGGAGATACCTGAGGCTATTGCT NO: CAAGCCCAGTCCTTGGACATTTAGTGACTGTTAGCCGGTCCCTTTCAGATCCAGTGGCCATG 995 CCCCCTGCTTCCCATGGTTCACTGTCATTGTGTTTCCCAGCCTCTCCACTCCCCCGCCAGAA AGGAGCCTGAGTGATTCTCTTTTCTTCTTGTTTCCCTGATTATGATGA ITGB7 ADXCRAG_M68892_s_at CTTCTCCTTGGAGGACAGTGGGAACTGGAGGGTGAGAGGAAGGGTGGGTCTGTAAGACCTTG SEQ ID GTAGGGGACTAATTCACTGGCGAGGTGCGGCCACCACCCTACTTCATTTTCAGAGTGACACC NO: CAAGAGGGCTGCTTCCCATGCCTGCAACCTTGCATCCATCTGGGCTACCCCACCCAAGTATA 997 CAATAAAGTCTTACCTCAG ADA ADXCRAD_CB158570_s_at GGGCAGAACCTCTGAAGACGCCACTCCTCCAAGCCTTCACCCTGTGGAGTCACCCCAACTCT SEQ ID GTGGGGCTGAGCAACATTTTTACATTTATTCCTTCCAAGAAGACCATGATCTCAATAGTCAG NO: TTACTGATGCTCCTGAACCCTATGTGTCCATTTCTGCACACACGTATACCTCGGCATGGCCG 1001 CGTCACTTCTCTGATTATGTGCCCTGGCCAGGGACCAGCGCCCTTGCACATGGGCATGGTTG AATCTGAAACCCTCCTTCTGTGGCAACTTGTACTGAA CD1C ADXCRAG_NM_001765_s_at ATTGCCTTGGTAGTGATAGTGCCCTTGGTGATTCTAATAGTCCTTGTGTTATGGTTTAAGAA SEQ ID GCACTGCTCATATCAGGACATCCTGTGAGACTCTTCCCCCTGACTCCCCCATTGTGTTAAGA NO: ACCCAGCAACCCAGGAGCCTAGTACAATATAGTGATGCCATCCCGTCGACTCTCCATTTAAA 1012 TTGTTTCTCTTTCTGCATAATAAA PTPN7 ADXCRAG_NM_002832_s_at GGAGGAGCTGCTCCTTCCTTACAGCCTTGGGGATGGACTTGCCCACACCTCCACCTCCCCTG SEQ ID AGCCCTGTGAGAGGCACGACTGTCTATGCCAATGAGGCTCGGTGGGGGGCTCTCAAGTGCCT NO: GATCCTGCCCTGGGCTCAGAGCCAGCCCAGAGGGAAGCAACTGCACAGCCCCACAGGCCCTC 1019 CCTGGCACTGTCCCCCCAACCCCATCTCAGAGCTCAGAGGGTACAAGCTCCAGAACAGTAA LCP2 ADXCRAD_BP306313_s_at CAGATATTATTGACTACTTCAGGAAAATGCCACTTCTGCTCATTGATGGGAAAAACCGAGGT SEQ ID TCCAGATACCAGTGCACATTAACGCATGCTGCAGGGTACCCATAGCAAGTTATAGCCGAGCA NO: AATGAACCGTCCTCCTGCCTCTGTTGCCAACACGAGATCAATCAGCCTTGGTCAATGGACAA 1030 ACACTTAGGACTGAACTGAACCCCTC IQGAP2 ADXCRAG_NM_006633_s_at CAACACAATAACACTTTCTGTATAAAAGTATATATTTTATGTGATTTATTCCTACTAAATGA SEQ ID AAGTGCACTACTGCCTCATGTAAAGACTCTTGCACGCAGAGCCTTTAAGTGACTAAGGAACA NO: ACATAGATAGTGAGCATAGTCCCCACCTCCACCCCTCACAATTTATTTGAATACTTCAATTG 1037 TGCCTCTCAATTTTTT TTF1 ADXCRAG_NM_007344_at ATCGCACCACCGCATGAGAGAGAGAGATTACTATTTCTTGTCCCTTTTTCTCAGTTTGATTA SEQ ID TATTTATATACATATGTCAGTAAATCTGTTTTCAGTATTGATGTTTAATAAAGAATGTACAA NO: TGGCCAGAGTTCTACTCTTTCCTCTGGAGCATTAAAATATATTGCCATTCCTATTAAAACGT 1038 ATTTG CALML4 ADXCRAG_NM_033429_s_at TACAAACTGACATTGTCTACTATACATTTTTAAAAGCCATTTTACTGGTTTGGCATGCGGTA SEQ ID TGGAAATTCTAAGAGAGAAAGTTTTAAGGCAATGAATCACAGATTTAAGTTCATGGAATTTA NO: TGGTAACTTTATCTGTTTATGTACATTTTCCCCTTTGTTAAACAATTAACAGCAGCACACTC 1048 TGGGACCACCAGCTATTTTCCCTCTCTTTCTGAAATCTAAGCTTTGT NFATC3 ADXCRAG_NM_173164_x_at CAGGTACCACGGCTCACGCCTGTATCCCAGCACTTTGGAAGGCTGAGGCGGGTGGATCACAA SEQ ID GGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGTAACGCTGTCTCTACTAAAAATACAA NO: AAAATTAGCCAGGCATGGTGGTGTGTGACTATAATCCCAGCTACTCGGGAGGCTGAGACAGG 1052 AGAATCACTTGAACCCGGGAGGTGGCAGTTGCAGGGAGCTAAGATCGCGCC TMPO ADXCRAD_CN272683_s_at CTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGT SEQ ID CATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGA NO: AATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAA 1061 ACAAATTTTGCCGAGCTTTTTTTGCCCTATATTTCCCAGCATAATTTGATTAGAAAGT SLC19A1 ADXCRAG_U17566_s_at GAAGTACGTCCCAGCGGCCTCAGGGTCTAAGGAGCGCTAGTGCCTTGCCCACAGGTGCGGGA SEQ ID CCATCTGATGTGATGTGAATACTCTTCCCACATACATTAAACACACTTA NO: 1064 MYB ADXCRAG_U22376_x_at GGGAATTCGTTCACAAATGTACTGATACCACAGATGTGGGCAGGGGCTAGGAGAGCAACAGG SEQ ID GTGCAGCCTGAAGGCACCTGGAAGGCCGCCTGGAGGGGGACAGTCAGGAAAGCAGGAGCCCT NO: TGAGAGGAGCACTAGCCTTTGATGAGACCACTGCCATCGAAGGAGACCTCACAGGGAGGGAG 1065 CCAAGGGTAAACCCTAACTTTGTTTCCCCATTTCTCCTATCTCTGCCTAGGGGTCCTCACTG GCAGAACCAACCAG BLM ADXCRAG_U39817_s_at GGGTCTGCCACATGTAGAAAGATATCTTCCAAAACGAAATCCTCCAGCATCATTGGATCCAG SEQ ID TTCAGCCTCACATACTTCTCAAGCGACATCAGGAGCCAATAGCAAATTGGGGATTATGGCTC NO: CACCGAAGCCTATAAATAGACCGTTTCTTAAGCCTTCATATGCATTCTCATAACAACCGAAT 1067 CTCAATGTACATAGACCCTCTTTCTTGTTTGTCAGCATCTGACCATCTGTGACTATAA HMGB1 ADXCRAG_U51677_x_at ATGATGAATAAGTTGGTTCTAGCGCAGTTTTTTTTTTCTTGTCTATAAAGCATTTAACCCCC SEQ ID CTGTACACAACTCACTCCTTTTAAAGAAAAAAATTGAAATGTAAGGCTGTGTAAGATTTGTT NO: TTTAAACTGTACAGTGTCTTTTTTTGTATAGTTAACACACTACCGAATGTGTCTTTAGATAG 1068 CCCTGTCCTGGTGGTATTTTCAATAGCCACTAACCTTGCCTG MAP4K1 ADXCRAD_BG397984_s_at TTCTGGAAGCATGGAGTGCAGGTGTGGGCTCTAGGCTCGGATCAGCTGCTACAGGAGCTGAG SEQ ID AGACCCTACCCTCACTTTCCGTCTGCTTGGCTCCCCCAGGCCTGTAGTGGTGGAGACACGCC NO: CAGTGGATGATCCTACTGCTCCCAGCAACCTCTACATCCAGGAATGAGTCCCTAGGGGGGTG 1070 TCAGGAACTAGTCCTTGCACCCCCTCCCCCATAGACACACTAGTGGTCATGGCATGTCCTCA TCTCCCAATAAACATGACTTTAGCCTCTGCAAAA GCN1L1 ADXCRAG_U88837_s_at TGATACTGCCCACCATACAGAAGTCCTTACTGAGGAGTCCAGAGAATGTTATTGAAACTATT SEQ ID TCTAGTCTGCTGGCATCAGTGACGCTTGACCTCAGCCAGTATGCCATGGACATCGTGAAAGG NO: ACTGGCTGGTCACCTGAAATCCAACAGTCCCCGCCTGATGGATGAAGCTGTGCTGGCACTGC 1077 GGAACCTGGCACGCCAGTGCAGTGACTCTTCGGCCATGGAGTCCCTGACCAAGCACCTATTT GCTATCCTCGGAGGCTCGGAAGGAAAACTAACTGTTGTAGCCCAGAA ATP5D ADXCRAG_X63423_at GCCCTGGAGTAGGCGAGCCAGCCGCCAAGGTTGACC SEQ ID NO: 1080 ATP5D ADXCRAD_CV025452_s_at CCACCTCCAAATACTTTGTGAGCAGCGGTTCCATCGCAGTGAACGCCGACTCTTCGGTGCAG SEQ ID TTGTTGGCCGAAGAGGCCGTGACGCTGGACATGTTGGACCTGGGGGCAGCCAAGGCAAACTT NO: GGAGAAGGCCCAGGCGGAGCTGGTGGGGACAGCTGACGAGGCCACGCGGGCAGAGATCCAGA 1081 TCCGAATCGAGGCCAACGAGGC ATP5G2 ADXCRAG_X69908_at TAAGATGTTTCTTGAGTCTCCTGTGTATATTTCTTTTCCACAGTTGGCTGAGTGCCTTCGTG SEQ ID AGAGTACAAGGCCCGAAGGGTAGTGATGGTGCTAAACTCAACATGGATTTGGCTGAGCTC NO: 1083 GCN1L1 ADXCRAG_XM_0457920_at TAAAGGCTTTGATTTAATCTTGATATAAACAGATTTTTAAAAATCTCCACCCATTAAACATG SEQ ID AAGCTTCCTGCATCAGGAA NO: 1085 GCN1L1 ADXCRAD_BU599568_s_at TCTTCTCCTGTGCTTGAGCTCTGGTTTGAGAGCTGGCGCTACCAACCTTTTTCCTATATCCC SEQ ID GAGTGGGGCACAGACGGTGGATCTCTGCCCAGTGTGGTGTGTCTGGCTTGGCTTTTCAATAT NO: TGTGAGGTCTGAATGGATCTGATCCCTGTCAGATGAAAATGATTCACAGCTCTGGCAGTTCC 1086 CAAGTCTGGGGAGGGGTATAGGTTTGAAAGGCTGTTTGAA CHD7 ADXCRAG_XM_0987621_at TTTAATAAAAGTGACCCATGATATGCAGAGATGTAA SEQ ID NO: 1087 CHD7 ADXCRAD_BU675017_s_at GGTCTTGTAATGCACTGGTAAAAACAAAATAAATAGATGAATAAATAAAGAGTGAGAGAAGA SEQ ID GAGAATCAGGTACCTTTTTTAAATTAAAGGACTTTGTTACTTTAGCCACAAAGCTAAAACAG NO: CATTACCTCAGCTCTAAACTAGCCTTGAAGTTTACAGACATGACTTTGTAAATGTATTGTTT 1088 TTCTTTGTTGTGATGTCCTTTTATTT CHD7 ADXCRAD_BU538327_s_at AACAGCCATCTTTTCAGCAGTTGCCAACCTGTCCTCCACTGCAGCCTCACCCGGGCTTGCAC SEQ ID CACCAGTCTTCACCTCCACACCCTCATCACCAGCCTTGGGCACAGCTCCACCCATCACCCCA NO: GAACACCCCGCAGAAAGTGCCTGTGCATCAGCATTCCCCGTCGGAGCCCTTTCTAGAGAAAC 1089 CAGCGCCGGATATGACTCACGTTAGTGGACCGAATGCTCAGCTAGTGAAGAGTGATGATTAC CTGCCATCAATAGAACAGCAGCCACAAC TMEM176B ADXCRAG_XM_377999_s_at TACAAGCCTCTATGTAAAGCACAGGCTGGTGAGGGCCCCAGGAAGAGCAGCACCGCCCTCGG SEQ ID CACAGGCCCCTACTCCAAGTCCTGTGCAGGAGCAGGTCTTGCCCAGCGCAGCAGCTCTGCAC NO: CTCTGTGGCACCGCTCTGCCAAGAGGGAAGGTGCAGGCCCTGCAGCCCATCGCCTTGGATCT 1093 GAAGACCAGCCCTGTGGGGCTGCTAAGTCATGAAACTGGCCTCATGGAGATTTCATAA GLTSCR2 ADXCRIH.292.C1_s_at TGATCGAGCCTCGAGAGAGAGCCAAGTTCAAACGCAAGTACTAGGTGAAGCTGGGTGGAGAA SEQ ID GCGGGCGTTCCGTGAGATCCAGTTGTAGCTGCCATCAGATGCC NO: 1102 MYC ADXCRIH.2640.C1_s_at TGATCAAATGCAACCTCACAACCTTGGCTGAGTCTTGAGACTGAAAGATTTAGCCATAATGT SEQ ID AAACTGCCTCAAATTGGACTTTGG NO: 1105 TOP1 ADXCRIH.2689.C1_x_at CTTGATTTTAAAGATCGTGTAGATTGGGGTTGGGGAGGGATGAAGGGCGAGTGAATTTAAGG SEQ ID ATAATGAAATAATCAGTGACTGAAACCATTTTCCCATCATCCTTTGTTTTGAGCATTCGCTG NO: TACCCTTTAAGATATCCATCTTTTTCTTTTTAACCCTAATCTTTCACTTGAAAGATTTTATT 1110 GTATAAAAAGTTTCACAGGTCAATAAAATTAG PSMB10 ADXCRIH.3674.C1_at TCGCGGCCCGTAGATAACGCGTGTAGCTCCATCTTGGACGCCACCATCCGTGTGGTCATCTC SEQ ID GGCGTCCGCGGCTACTCCAGCCCCACAGCAGTAGATTTTGGGGGCGATGAAGTGGATCTTCT NO: CGCAGCTCTTGTCCGCCACGACCGAATCGTTAGTGGCTCGCGTATCGGCGCCCAGAATGACC 1114 CCCGTCTTGGAACACCAAGCCCGCGATGGTGGTCCCGGTCTTGCGTGCGTGAAGGGACCTTG AGCCCCGGGAGGACGCGTTCCAATGATGCATTTT CNBP ADXCRIH.383.C1_s_at GGAAAGAGCAACTGAAGTCCTAGAAAATAGAAATGT SEQ ID NO: 1131 ANP32B ADXCRIH.2787.C1_s_at ACATTCCGCCTTCCTTCCATGTAGTCCCTCTTGGTAATCTACCACCAAGCTTGTGGACTTCA SEQ ID CTCCAACAAAATTGTAAGCGTTGTTAGGTTTTTGTGTAAGATTCTTGCTGTAGCGTGGATAG NO: CTGTGATTGGTGAGTCAACCGTCTGTGGCTACCAGTTACACTGAGATTGTAACAGCATTTTT 1143 ACTTTCT MRPL16 ADXCRIH.2001.C1_s_at ACATGCTGGGCATACGGAAAGTACTGAGCCCATATGACTTGACCCACAAGGGGAAATACTGG SEQ ID GGCAAGTTCTACATGCCCAAACGTGTGTAGTGAGTGTAGGAGATAACTGTATATAGGCTACT NO: GAAAGAAGGATTCTGCATTTCTATTCCCCTCAGCCTACCCACTGAAGTCTTTGGGTAGCTCT 1144 TAAGCCATAACTAAGGAGCAGCATTTGAGTAGATTTCTGAAA TUFM ADXCRIH.1094.C1_s_at TAGAGAAAGGCCAGCGTTTCACCCTGCGAGATGGCAACCGGACTATTGGCACCGGTCTAGTC SEQ ID ACCAACACGCTGGCCATGACTGAGGAGGAGAAGAATATCAAATGGGGTTGAGTGTGCAGATC NO: TCTGCTCAGCTTCCCTTGCGTTTAAGGCCTGCCCTAGCCAGGGCTCCCTCCTGCTTCCAGTA 1146 CCCTCTCATGGCATAGGCTGCAACCCAGCAGAGGGCAGCTAGATGGACATTTCCCCTGCTCG GAAGGG PIM2 ADXCRIH.2055.C1_s_at AGTGGATCTCTCGACACCAGTACCATGCACTCCCGGCCACTGTCTGGTCACTGGGCATCCTC SEQ ID CTCTATGACATGGTGTGTGGGGACATTCCCTTTGAGAGGGACCAGGAGATTCTGGAAGCTGA NO: GCTCCACTTCCCAGCCCATGTCTCCCCAGACTGCTGTGCCCTAATCCGCCGGTGCCTGGCCC 1149 CCAAACCTTCTTCCCGACCCTCACTGGAAGAGATCCTGCTGGACCCCTGGATGCAAACACCA GCCGAGGATGTACCCCT PFDN5 ADXCRIH.3098.C1_s_at GATAGATTTTCTAACCAAGCAGATGGAGAAAATCCAACCAGCTCTTCAGGAGAAGCACGCCA SEQ ID TGAAACAGGCCGTCATGGAAATGATGAGTCAGAAGATTCAGCAGCTCACAGCCCTGGGGGCA NO: GCTCAGGCTACTGCTAAGGCCTGAGAGTTTTTGCAGAAATGGGGCAGAGGGACACCCTTTGG 1158 GCGTGGCTTCCTGGTGATGGGAAGGGTCTTGTGTTTTAATGCCAATAAATGTGCCAGCTGGG C RPL3 ADXCRIH.445.CB1_s_at CCTTGCTGGTGCAGACGAAGCGGCGGGCTCTGGAGAAGATTGACCTTAAGTTCATTGACACC SEQ ID ACCTCCAAGTTTGGCCATGGCCGCTTCCAGACCATGGAGGAGAAGAAAGCATTCATGGGACC NO: ACTGAAGAAAGACCGAATTGCAAAGGAAGAAGGAGCTTAATGCCAGGAACAGATTTTGCAGT 1162 TGGTGGGGTCTCAATAA MSH2 ADXCRIH.1841.C1_at AAATGGCTGGTCGTACATATGGAACAGGTGCTCCATTTGACACGTGAGCAAAGCTGACAACA SEQ ID GCATCTAGCTGAGCTAACACATCATTGAGTGTCTGCATTGGTTCTACATAGCCTGAAGAAAT NO: ATTGACAATTTCTTTAACAATGGCATCCTGGGCTTCTTCATATTCTGTTTTATTTTTGGTAT 1164 ACTCTTCATTTAAAGAAGTCAATTTGCTGTTGGTAAATTTAACACCATTCTTCTGGATATCT AC TPT1 ADXCRAD_NM_017627_s_at GGGACTGATGTCATCTTGAGCTCTTCATTTATTTTGACTGTGATTTATTTGGAGTGGAGGCA SEQ ID TTGTTTTTA NO: 1167 TPT1 ADXCRIH.18.CB1_x_at ACTCATCAATTAACTTCTACAGTGGAGACTACTTCTGGGACTGGAATATAAAAAAGAATCAA SEQ ID AGGTTCTGATTTTGAGTTGCAATAAAGGGAAAGACCATGCTCATAGCAGTGCCAACATCTGA NO: AGTGTGGAGCCTTACCCATTTCATCACCTACAACGGAAGTAGTTAACTGGAAGAGATTACCA 1168 AGAGAATAAAAAGAGACTCATTCAGTGGAACCAACCTCGTGCAGCCCGGG SLC9A3R1 ADXCRIH.2825.C1_s_at TTTTGTTAAGAGTGCAGTATTGCAGAGTCTAGAGGAATTTTTGTTTCCTTGATTAACATGAT SEQ ID TTTCCTGGTTGTTACATCCAGGGCATGGCAGTGGCCTCAGCCTTAAACTTTTGTTCCTACTC NO: CCACCCTCAGCGAACTGGGCAGCACGGGGAGGGTTTGGCTACCCCTGCCCATCCCTGAGCCA 1169 GGTACCACCATTGTAAGGAAACACTTTCAG NDUFAB1 ADXCRIH.1103.C1_s_at TTGGGTTTGAAATTCCTGATATAGATGCTGAAAAGTTAATGTGTCCACAAGAAATTGTAGAT SEQ ID TACATTGCAGATAAGAAGGATGTATATGAATAAAGTATCAGACCCTTTGGCTTTGCTGAGAG NO: AGGACTCAGATGATAGTGACGAATGTCTGGCAGTGAGGACACATTTTGGCATTCTTGCTGAC 1172 TCTGACAGAGTGATTCTGATGGACTTGTATTTAA AKAP1 ADXCRAD_NM_139275_s_at TTCTATTTGTGCAAACTCTGTAAATATGTGTTTAAACAAATGTAATATTTTGTACAAGATAC SEQ ID ACTGGAGAACAAAGGGAACTCAAGATTCTTCCAGCCACATGTCACCTGTAGGTAGAAGTAAA NO: CTCTGCAGTGCAGCTTCTGCTCTTGGCCCCTCTGGCCAGGGCCCCTGTGGCTTCCTGCACAC 1173 TGGACAGGTGACTGTATGGTAGAGACTGTGATCTGGGAACTTTTTGCTGTACAAATCTGT IL2RG ADXCRIH.841.C1_at GGGAATCTCACTGACGAGGCAGAGTCGTTCACTGTAGTCTGGCTGCAGACTCTCAGCCAGTC SEQ ID CCTTAGACACACCACTCCAGGCCGAAAAGTTCCCGTGGTATTCAGTAACAAGATCCTCTAAG NO: TTCTTCAGGGTGGGAATTCGGGGCATCGTCCGTTCCAGCCAGAAATACACACAGAGAAGGCT 1179 GATAATCAATCCCATGGAGCCAACAGAGATAACCACGGCTTCCAATGCAAACAG IMPDH2 ADXCRIH.1164.C1_at CACATTTTGGATTCCTCCATCAGCAATGACCGGAACACCAAAGCGCCGTGCATACTCTGACA SEQ ID CCTTGTACACTGCTGTTGCTTGGGGCCGCCCACAGGCCAGCACTTCCTGCGTAATGCAGATG NO: GAGCCCACTTCCCATGCCCACCCGCAGGGCATCCACACCTGCATCAATGAGGTTCTTGGCCT 1184 GGGCAGCAGTGACCACATTGCCTCCAATGACTTGGAGATTAGGGTATTTGTCTTTGATGTAC TTGATCATATTGATCTGGAAGATGGAATTTCCCTGGG MTHFD2 ADXCRIH.873.C1_s_at GCTGCAAAAAAGGTGCTGAGGCTTGAAGAGCGAGAAGTGCTGAAGTCTAAAGAGCTTGGGGG SEQ ID TAGCCACTAATTAACTACTGTGTCTTCTGTGTCACAAACAGCACTCCAGGCCAGCTCAAGAA NO: GCAAAGCAGGCCAATAGAAATGCAATATTTTTAATTTATTCTACTGAAATGGTTTAAATGAT 1189 GCCTTGTATTTATTGAAAGCTTAAATGGGTGGGTGTTTCTGCACATACCTTCTGCAGTACCT CACCAGGGAGCAT TMPO ADXCRIH.3127.C1_at GAAATTGTGAGAAGCTTCATTTAGTGTTTAAAAATGTGGGGAGATAAATCAGACTTAACATG SEQ ID TATGTAAGATCAATTCACTTAAAAGTATGGTCCAAATAGCAAAAATAGGACCAGGTGAAACA NO: TGTAGTCATTTTTTAAAAACATGTACTTGGTCTTTTGTGTGTGTCTGTTTTATTCCATTAGA 1197 ATAAATGTGTCCTTGATGTAATGCAAAGCATTTCTTCCTGATTAAATTGTAGATGTAGACTT TAC TMPO ADXCRIH.3127.C1_x_at TCCCATACTGTTTTCAGCCTTTTGTTTATAATTAGAAATTGTGAGAAGCTTCATTTAGTGTT SEQ ID TAAAAATGTGGGGAGATAAATCAGACTTAACATGTATGTAAGATCAATTCACTTAAAAGTAT NO: GGTCCAAATAGCAAAAATAGGACCAGGTGAAACATGTAGTCATTTTTTAAAAACATGTACTT 1198 GGTCTTTTGTGTGTGTCTGTTTTATTCCATTAGAATAAATGTGTCCTTGATGTAATGCAAAG CATTTCTTCCTGATTAA PTPN2 ADXCRIH.138.C1_at GCAAAGCAAGACCTGAAGCCCACTCCGGAAACTAAAGTGAGGCTCGCTAACCCTCTAGATTG SEQ ID CCTCACAGTTGTTTGTTTACAAAGTAAACTTTACATCCAGGGGATGAAGAGCACCCACCAGC NO: AGAAGACTTTGCAGAACCTTTAATTGGATGTGTTAAGTGTTTTTAATGAGTGTATGAAATGT 1199 AGAAAGATGTACAAGAAATAAATTAGGAGAGATTACTTTGTATTGTACTGCCATTCCTACTG TAT LBR ADXCRIH.2185.C1_s_at TTGTTTTATCAGTGCTAATGTGTGCAAGCAGTTTTTTTATTTTGCTTTTCTCCTGGCATCAG SEQ ID AAAGTGGTGGCGTTTTCTGTACTGGATTGCACCAAGGAAGCTTTTGGGGAGGAAGGAAGGAC NO: ATTAAATTCTTTCCCTGGTAATGAAAAGAGCCCTTTATCAATACAGTGCTGCAATTTCTGGA 1200 TATCAGCTACACTTTGTTTT SP110 ADXCRIH.149.C1_s_at ATCCTCAGTGAAGTGCATTCGGAATGAGGATGGAACTTGGTTAACACCAAATGAATTTGAAG SEQ ID TCGAAGGAA NO: 1202 SP110 ADXCRIH.149.C1_x_at ATATACGTTGTGAAAGGACGACCCTAGGAGAGCTGCTGAAGAGTGGACCTTTGCTCTGTCCT SEQ ID CCAAGAATAAATCTCCAGAGAGAGTTTAAATAGCAAGTGAATTTCTACTACC NO: 1203 TMEM176B ADXCRIH.2580.C1_s_at CCTTCGCCCTCTAGGGAGCAGACCTCCACTGCCATTGTCCTGTGAGCCGCCAAAGACCCCAC SEQ ID GGGGTGCCCGCATGTCCCTGTCTAGGGCAGCCCAGGGCCCCCACTCCTGGCTCCTCACACTT NO: GCCTCCCCTATGGCCGCTCTCCAGACCCTCCTCCTTTCTTCTCCCCACATCCGCACCTGCTG 1215 TTCCCACTCTGGGGTTCTCAAGTCCATGAACAGATATTGTTGCATTTTCCACAATG ATHL1 ADXCRIH.1963.C1_s_at GATGTTCGCAGGAAAAATCTGGAGATTTACGAGGCTGTGACGTCCCCCCAGGGCCCCGCCAT SEQ ID GACCTGGAGCATGTTTGCTGTGGGCTGGATGGAGCTGAAGGACGCAGTGCGGGCCCGGGGCC NO: TCCTGGACAGGAGCTTTGCCAACATGGCTGAACCCTTCAAGGTGTGGACGGAGAATGCAGAC 1222 GGGTCAGCGCTGTGAACTTCCTGACAGGCATGGGGGGCTTCCTGCAGGCGGTGGTCTTCGGG TGCACGGGGGTTCAGGGTCACCCGAGCGGGTGTGACCTTTGAC PAICS ADXCRIH.2946.C1_at TTGAATTTACCGTCTTCTCATCCTCTGTACAAAAGCCTCAAGTGAGGGTCAAATTCAACATT SEQ ID ATCCTGATCTAGACAGCCCCCATTCTCAATCCACCCTTTTCCAAGTTGATTGCCCAAGGACT NO: TCTAACAATAAACTCTCTTTTGCACCACAGACTTCTTTGAAAATATACATGCTGTTGACCCT 1228 CTCTGTAGAAAACCGCACACATAAAACTTACCAACAGATTTCATTGGTTCTTGGGTTCTCCC GAAGCCTATCCATGGTTTATA MYB ADXCRIH.2957.C1_at ATCAAATGCAAAACTCCCAAATTATAAAACAGTCAGGCTACACTCAAAACAAAACATAGAAC SEQ ID ATCAACAACACACATCTCCCAAAAAAGAAGTGCAACGCATGCTTGTATAAACCAACAATAAC NO: AAAAAAACCACAATAAAAAATGCAGAGTCTCCCAAACAAGTTTTCAAATGTATTGCAGAAGN 1232 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTCTGAAATACTAGTGCATAGTCAATTACC TAACACCAAGTT REPIN1 ADXCRIH.2978.C1_s_at CTTTTCTCCATTTCTAGCATATGGACACCTGGCCTCTGCTTGAGCACTTAGGTGACAGGAAC SEQ ID TTCCGCACCTCCTGAGGCCCTGGATGATTCTAATTGTTAGAAATTCTAATTGTTAGAAATCC NO: TTCCTTATAATGAATGAATTCTGCTTTCCTATAATTTCTACCTATTGGGCCTTGTTCTGTTC 1236 TCTGGAACTAAAC NCKAP1L ADXCRIH.2983.C1_at CGACCTTCATCCACTATTCTTATGATAATGCTGGCGGGCAGAGATGATCAATCTCCTATTAA SEQ ID ATCAT NO: 1237 NCKAP1L ADXCRIH.2983.C1_s_at CAGGAGCCAGAGTTGATGAGCAGATCTGTGGAAGAACAATCCAGGGCTGAGAAATCGTAGAG SEQ ID CAGTGAGGCAGGCTGGGAGCATGGAGGACAGCTTATGGAAAAAGTTAGGGCGTGGGGCCACA NO: TGTGTGAATTTTAC 1238 USH1C ADXCRIH.2211.C1_s_at ACCAGGGCCAGATAAGGAACAGCTCGGGCCACTCTTCTGAAGGCCAACGTGGAGGAAAGGGA SEQ ID GCAGCCAGCCATTTGGGAGAAGATCTCAAGGATCCAGACTCTCATTCCTTTCCTCTGGCCCA NO: GTGAATTTGGTCTCTCCCAGCTCTGGGGGACTCCTTCCTTGAACCCTAATAAGACCCCACTG 1242 GAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAATTGCTGCCAGGATTGTCAC TCCA TMPO ADXCRIH.994.C1_s_at ATATCCTGGGATAGTGCATGTTCACCATCTATTTTGTCAGATAATGGGGCCTTTTAAAAAAT SEQ ID AATACTTTGCTTTCATGATATATTGTATTTTTGTGGAAAGTTAAGTTTAGCAATATATACTC NO: TAAAAGCAAATTTAATTTTTTTTAAGCCATAAAGAAATTATACTATATCCCAGTATCTGTAT 1247 GTCTGTATAAAGCAGTGTATTATC GCH1 ADXCRIH.1611.C1_s_at TTCTGAGCACTCAACTCATGTTTGGCATTTTAAAGTAAAAACAAGTGTGACTTCGAGGACCA SEQ ID AAGAAATTGTCAGCTATACATTTATCTTTATGAACTCATTTATATTCCTTTTTAATGACTCG NO: TTGTTCTAACATTTCCTAGAAGTGTTCTTATAAGGTCTAATGTATCCACAGGCTGTTGTCTT 1252 ATTAGTAAATGCAAAGTAATGACTTTGTCTGTTTTACTCTAGTCTTTAGTACTTCAAATTAC CTTTTCATATCCATGATCTTGAGTCCATTTGGG HNRNPA2B1 ADXCRIH.840.C2_s_at ACACAGTCTGTAAGCTTTCCCCATTGTTCGTAGTAGTTCCTCAAACTTTCTTCTGTGGTTTC SEQ ID AAAGCTTAAGCCACCAATAAAGAGCTTACGGAACTGTTCCTTTTCTCTCTCCATCGCGGACT NO: CAGTCGCTTCAGCCCGATTTCCCGCAGCCGAGCGAGATGAGAGAGATCTCCGCGGACGAACA 1263 CGAACCGGACTCGTCCTGGCGCTGTAGTGAGAACTGCCGCTGCTCGAGAAACAACTCTGCGA RPS6 ADXCRIH.344.CB1_x_at GACCAAAGCACCCAAGATTCAGCGTCTTGTTACTCCACGTGTCCTGCAGCACAAACGGCGGC SEQ ID GTATTGCTCTGAAGAAGCAGCGTACCAAGAAAAATAAAGAAGAGGCTGCAGAATATGCTAAA NO: CTTTTGGCCAAGAGAATGAAGGAGGCTAAGGAGAAGCGCCAGGAACAAATTGCGAAGAGACG 1266 CAGACTTTCCTCTCTGCGAGCTTCTACTTCTAAGTCTGAATCCAGTC DENND2D ADXCRIH.1679.C1_s_at GGTATTGCTTCAAACTGGTGTCTGAGATTTGGATCCCTGGTATTGATTTCTCAGGACTTTGG SEQ ID AGGGCTCTGACACCATGCTCACAGAACTGGGCTCATAGCTCCATTTTTTGCAGAGGTGACAC NO: AGGTAGGAAACAGTAGTACATGTGTTGTAGACACTTGGTTAGAAGCTGCTGCAACTGCTCTC 1274 TCCCATCATTATAACATCTTCAACACAGAACACACTTTGTGGTCGAAAGGCTCA PCBP2 ADXCRIH.132.C4_s_at GAGATGTTGATACGTGCACCACTCTCCTCGCGCATCTTCTTAACTGATTCTCCTTTCTTTCC SEQ ID GATGATACTGCCAACTTCCTTTCCATGCATAAGTAGCCGGATGGTGAGAGTGACATTTAATC NO: CACCTTCAATCACACCGGTGTCCATGTCGAGCAGTGTTCTGGGGAGCTGGACTTTGAGTGGT 1286 CAAGTCTTTGGTCACTGGT HMGB1 ADXCRIH.157.C4_s_at TTTAGTAGGTACGTCATGACAACTACCATTTTTTTAAGATGTTGAGAATGGGAACAGTTTTT SEQ ID TTAGGGTTTATTCTTGACCACAGATCTTAAGAAAAT NO: 1289 RPLP0 ADXCRIH.6.CB1_s_at CAAACGAGTCCTGGCCTTGTCTGTGGAGACGGATTACACCTTCCCACTTGCTGAAAAGGT SEQ ID NO: 1292 NAP1L1 ADXCRIH.187.C2_s_at TGAAAACTTCCTTTCTGAGAAGTTAGTGTTAAGGTCTTGGAATGTGAACACATTGTTTGTAG SEQ ID TGCTATCCATTCCTCTCCTGAGATTTTAACTTACTACTGGAAATCCTTAACCAATTATAATA NO: GCTTTTTTTCTTTATTTTCAAATGATTTCCTTTGCTTTGATTAGACACTATGT 1301 PSMB10 ADXCRIHRC.3674.C1_s_at TCACCGCCGGGATCTTGGGTGACCTGGGCTCCGGGGGCAATGTGGACGCATGTGTGATCACA SEQ ID AAGACTGGCGCCAAGCTGCTGCGGACACTGAGCTCACCCACAGAGCCCGTGAAGAGGTCTGG NO: CCGCTACCACTTTGTGCCTG 1307 IL2RG ADXCRIHRC.841.C1_s_at ATGCAACCAGCATAGCCCCTACTGGGCCCCCCCATGTTACACCCTAAAGCCTGAAACCTGAA SEQ ID CCCCAATCCTCTGACAGAAGAACCCCAGGGTCCTGTAGCCCTAAGTGGTACTAACTTTCCTT NO: CATTCAACCCACCTGCGTCTCATACTCACCTCACCCCACTGTGGCTGATTTGGAATTTTGTG 1316 CCCCCATGTAAGCACCCCTTCATTTGGCATTCCCCACTTGAG TMPO ADXCRIHRC.3127.C1_at TGAAATCAAAATTGTGTGCTGGTCTAAATATACATCTTCGGCTTCTTCCTTTTTAGTAAGTA SEQ ID TTTTTATTTCAGATGTATTTAAAAATAACTTACATTTTTAGTGTGCTTTATGGTCAATGACT NO: GTAAAGTTGAAACTCAAATGAGTCAGTTTAAAATTTTTGTCTCATTTGATTCTATTGAAATT 1320 TTAATCACCTACTACTTTAATCAAGTTATTCATGAGGTAAGTTTCAGCT MYB ADXCRIHRC.2957.C1_s_at GATGTGTGTTGTTGATGTTCTATGTTTTGTTTTGAGTGTAGCCTGACTGTTTTATAATTTGG SEQ ID GAGTTTTGCATTTGATCCGCATCCCCTGTGGTTTTTAAGTGTATGGTTTCAGAACTGTTGCA NO: TGGATCCTGTGTTTGCAACTGGGGAGACAGAAACTGTGGTTGATAGCCAGTCACTGCCTTAA 1325 GAACATTTGATGCAAGATGGCCAGCACTGAACTTTTGAGATATGACGGTGTACTTACTGCCT T REPIN1 RDCR241_B04_at CCTGTGCACAGTCTGACACTGGGAATGAGTGACCTTTGTGTTCCCTGAGAAGAGAGAGTGCG SEQ ID CTCTAGGGAATTTAGAAGGATGTGTCTGGAGCTTGTGAGCAGGCACAGAAGGGCCCTTAGGA NO: GCCTAACTGCTTCCTTCCTCCTTCCGCGGAGGAGGCTCCTGTGCAGGAATCTGGGCTCCCCT 1339 GAGCTGTGGAAGAGCTGAACATGGGGCAGCCCCTGGCGAGGTTGGGGCAGGACCGGGCAGGG GACTGAGATTGCAGTCTCATCTTCCC RNF44 RDCR179_F10_x_at CTGGGCGAATCTCCTCCAAGGAAGTCCCAGGAGGATGGGGACCAGGAAGGCTGTGGACCCCC SEQ ID ATCTCCAGGGGGCCTTCCCAGCCTGATCCCTGTCCTCCAAGTTCTGGAGGAGGCCGGTGTAG NO: GGTCTGGCTGAACTTCCCACCCACTTTCCCTGGTCCCAATCCTTTCTTGTCCTATACCAAGC 1351 TGGGGTTGCTGCCTTGAACGAACTGCGTGTGTTTTCGTCACATCCTATCAGGCAGCCCCTGG CGTCTGCTGCCTCAGGTATGCTCCAA LGALS9 RDCR039_D09_at CATAAGGAGACTAGGCAGCCATGGGTAACACCTCACAAGGAAATGAGCGTGTTATCTGTATA SEQ ID GTGGTGTCACTCTGGCTGAATGTCAATTTAGGTGATTACTTAAAGGCCATTCACCTGATAGG NO: GCTGGGGGTCCCAGGGGTGAGAGGTGGGGAGGGGATTCTTGCTCACCTTGAAATCTGAGCTC 1354 TGCACCAGGAAGCAGAGGTCAAAGGGCATCTCCTTCTGGAAAGGCATGTGTGTCTTCCTCTC CCTCGGGCCCCCAGCTTCCGTTCTGCCTCGTGTTG LRMP RDCR162_D09_s_at TCCTGGGCAACAAATCTCAAGTCCTCCATCAGAAAGGCTAATAAGGCTCTCTGGCTCTCTAT SEQ ID TGCATTCATTGTACTGTTTGCAGCTTTGATGAGCTTCCTCACAGGCCAATTATTCCAGAAGT NO: CTGTGGATGCCGCTCCCACACAGCAAGAGGACTCATGGACGTCTCTAGAACATATCTTGTGT 1359 CATTTACCAGACTCGACACAATGGGCCACCACCAGTGTGACAGCAGACATCCTAATATATGG ATCTTGAT GTF3A RDCR434_D07_at AGGTTAAAGCAGTTGGGAGTCCATACACAGCCTACCCAACTTCCTGAAACTCTTAGAGAGGA SEQ ID AAAGGCATCCTTAGGCATCCTTCCTGTGAAGTTTGCCTATTCCGTGATCACGCTGAGAAGAT NO: GGGAACTCTGAAGTTTGCTTCACAAGAAGGTAAAATCCTTAAAGGGAGGCACCTTGCTGTGC 1369 CACTGTTCAGTTTTACTATAACATCAATCTTTTTTTAGTTTTTATTCCCACCTCAAGAGGCT GAGTTGAATACTATTAGGC CALML4 RDCR490_C03_at GGGAGCAGCACGAACTCCTGAAGACTTGGGAGCGTCAGCAGCTTCTGCGGAAGGGGTGGGGC SEQ ID TGAGGGTGGAGAGAGGAAGGGAAGGAAGAAAAGGGGAGCCTTCCTGGCCAGGGTAACCGGCA NO: CTAAGAGGCCTCACTCCAAGCCCCCGAGGAGCCTGTGGTGGGGCTGGAGACCCGGGCTCAGC 1373 CCCTCCACCACCCTTAAAGTCCTCAGAAGGTGGGAACTGAACTGGGCACAGGCTGGGAAACC GGCTGTGCGCTGGGCACTTGGAT CALML4 RDCR490_C03_x_at GAGCAGCACGAACTCCTGAAGACTTGGGAGCGTCAGCAGCTTCTGCGGAAGGGGTGGGGCTG SEQ ID AGGGTGGAGAGAGGAAGGGAAGGAAGAAAAGGGGAGCCTTCCTGGCCAGGGTAACCGGCACT NO: AAGAGGCCTCACTCCAAGCCCCCGAGGAGCCTGTGGTGGGGCTGGAGACCCGGGCTCAGCCC 1374 CTCCACCACCCTTAAAGTCCTCAGAAGGTGGGAACTGAACTGGGCACAGGCTGGGAAACCGG CTGTGCGCTGGGCACTTGGATTTTGCCAGCTGC RPS6 RDCR236_E11_at ACATACTTTGTGCATTTTTCACTGATCCAAGAATGTTTTTAGTCATTTCCTTTTCAGTGTGT SEQ ID GAACAGCCTAACAATTCACTGGAGTTGAAAAGCTTTGTTAAAACAAATTTGAAATGGCTTAA NO: AAACCATTTAGTGGATGGTATCCACTAAAACTAGGTATCCACTAAAACTATGCCTTAAAAGT 1377 TACCTTTTAAAAAAGACATGTTCATCTTCACAAGGTCAATTTTCATGTATTAAATTGTGTAT AGTGCTTTAAAGAGCTATATTCCTCAAAAATA GTF3A ADXCRIHRC.2186.C1_s_at GGCCTCTCATCTCAGTGGATATATCCCTCCCAAAAGGAAACAAGGGCAAGGCTTATCTTTGT SEQ ID GTCAAAACGGAGAGTCACCCAACTGTGTGGAAGACAAGATGCTCTCGACAGTTGCAGTACTT NO: ACCCTTGGCTAAGAACT 1382 RPL10A ADXCRIHRC.799.C2_s_at AGGTGTTATGTCTGGCTGTAGCTGTTGGTCACGTGAAGATGACAGACGATGAGCTTGTGTAT SEQ ID AACATTCACCTGGCTGTCAACTTCTTGGTGTCATTGCTCAAGA NO: 1384 BLM ADXCRPD.16944.C1_at TTAGGGCCTTTGCTCTAGCCAAAGCTTCTTGCAGGAAAGCTCACATCCAGGGAGCTGCCAGC SEQ ID TAACTCCCTTCTTCAAGATTTTCCTCAGCTCCCATCTTCTCAGTTAGACTTCCAAGGACCAC NO: CCCGTCTAATACTGCATCCTGCACTCTACCCATTCCTCCTGTCTTTTTACTCTGCTGTGCCA 1385 TTCACCACAGCTCTTATCCTTTCATGTATATTTATTGTGTATATTGTTTGTAACTGGCCTCC CTCTGCTAGAGTGTAAG SLC19A1 ADXCRPD.7962.C1_s_at GCCGCGGGCTTCGTGAAGATCCGCTGGGCGCGCTGGTCCAAGCTGCTCATCGCGGGCGTCAC SEQ ID GGCCACGCAGGCGGGGNCTGGTCTTCCTTCTGGCGCACACGCGCCACCCGAGCAGCATCTGG NO: CTGTGCTATGCGGCCTTCGTGCTGTTCCGCGGCTCCTACCAGTTCCTCGTGCCCATCGCCAC 1389 CTTTCAGATTGCATCTTCTCTGTCTAAAGAGCTCTGTGCCCTGGTCTTCGGGGTCAACACGT TCTTTGCCACCATCGTCAAGACCATCATCACTTTCATTGTCTCGGACGTGC PPRC1 ADXCRPD.9220.C1_at CAGGTATTGAAACAAGTTAACTTGCATTCCTATGTAAGATAGGAGGGGCTGAGGGGATCCCC SEQ ID AGTGTTTGGAACATAAGTCACTATGCAGACTAATAAACATCAACTAGAG NO: 1398 PPRC1 ADXCRPD.9220.C1_x_at TCCCTGCTATCCTTTTTCTCCTTTGGAGGTGCNCCAACCTCCTCCACCCCCTTCCCCTACTC SEQ ID TAGGGGAGAGAGCTGCTAGTGAGATGACTGTTTTATAAAGAAATGGAAAAAAGTGAAATAAA NO: AAATATGTTGAATCAGATTTTTTAAAAGGGGTATTTGTTTTTTTATAACAGGTATTGAAACA 1399 AGTTAACTTGCATTCCTATGTAAGATAGGAGGGGCTGAGGGGATCCCCAGTGTTTGGAACAT AAGTCACTATGCAGACTAATAAACATCAACTAGAG ITM2A ADXCRPD.18289.C1_at GTAACCTTGGCATCTTTATTTACCAACTTTGCAATAACAGAAAGTCCTTCCGCCTTCGTCGC SEQ ID AGAGACCTCTTGCTGGGTTTCAACAAACGTGCCATTGATAAATGCTGGAAGATTAGACACTT NO: CCCCAACGAATTTATTGTTGAGACCAAGATCTGTCAAGAGTAAGAGGGCACAGATAGAGTGT 1403 CCTTGGTAATAAGAAGTCAGAGATTTACAATATGACTTTAACATTAAGGTTTATGGGATACT NNCAGATATTACTCATGCATTTACTCTAATGCTTTATGCTTTA AQP3 ADXCRPD.10405.C1_at GGGCCACAGATTAGGTTGGAGCTCTGGATGTACATACATAGTATGAGCAGTGGGACGTGTTT SEQ ID CTGTCTTAATGCAGGCATCAAGGGTGGAGTGAAGTCAGGTCATAAGTGTCATGTCCGCTTGG NO: GTTTTGTTTTGTTTTTAATGTATGTAGCAGATGTTACAGTCTTAGGGATCCGGGATGGGAGA 1410 CCCCACTTTAGAAAGGGTCGTCACTCCTTTAATCCTCTACTCAACAATGTACTCTTTTA PAICS ADXCRPD.2080.C1_s_at GCTCTGATGTGCTATGCTTAGCTATCTGTCAGAGATTAGTAAATTATAAAACTCATGTGTAC SEQ ID TACTTAAGTTTATATCTTATGCTAGTTTATAAGAACAATTAAAAGGACTTAGAAGATTAACT NO: TTGGTTTCATGGTCTCTGAAGTCACTGACTGCTATTTCAGCTTGTTTACCCTTACCTAGCAT 1415 TAAGACTCCATCTACTTCTGTGCAGTATATGAAAATTTTTAAACTTTCATTTAGACTGGTGG ATAGGACTGACCATTACAAATTGT GMFG ADXCRPD.1437.C1_at TGATCTCTGGGCTGGGGACTGAATTCCTGATGTCTGAGTCCTCAAGGTGACTGGGGACTTGG SEQ ID AACCCCTAGGACCTGAACAACCAAGACTTTAAATAAATTTTAAAATGGCGCCAGGCCCCCCC NO: ACGTAAAAGAAAANAACTTGTTCGGCCGCCCTCGGCCCCTCAAAAAACTTTTCTAAACCCTT 1417 TCGTTTGGGCCCCCGGGGCCCACTTAGGTAAGGGAAAAATGGGGCCTAAACCTGTTTCCCTA GGAAAATCCCTTGGCCATGAACTAA USH1C ADXCRPD.18376.C1_s_at GTCCATCAAAGTGAGACACATCGGCCTGATCCCCGTGAAAAGCTCTCCTGATGAGCCCCTCA SEQ ID CTTGGCAGTATGTGGATCAGTTCGTGTCGGAATCTGGGGGCGTGCGAGGCAGCCTGGGCTCC NO: CCTGGAACATCGGGAAACCAAGGAGAAGAAGGTCTTCATCAGCCTGGTAGGCTCCCGAGGCC 1421 TTG ATP5G2 ADXCRPD.11199.C1_s_at AAGAATAGACTAGGGCCTCAGTCTTACACTTCTTGACCACACCTGAATCTTAAAGGCATTTG SEQ ID AAGTCTACATCCTACGTTAAAAGGTTCTACTTGCCAGCATTTTAGGGCGTTAAACAA NO: 1439 IL2RG ADXCRPD.2198.C1_at AACCACTGTTTGGAGCACTTGGTGCAGTACCGGACTGACTGGGACCACAGCTGGACTGAACA SEQ ID ATCAGTGGATTATAGACATAAGTTCTCCTTGCCTAGTGTGGATGGGCAGAAACGCTACACGT NO: TTCGTGTTCGGAGCCGCTTTAACCCACTCTGTGGAAATGCTCACCATTGGAAGTGAATGGAG 1440 CCACCCAATCAACTGGGGGGAGCAATACTTNCAAAAGAGAATCCTTTTCCTGGTTGCAT LCP1 ADXCRPD.1593.C1_at GGGTGTAATGGGAGCATCCAGCCACTCGGCGGGCAGCATGGAGCTATAAACTAGCCATCCCT SEQ ID TTTAGGGGTTCTGC NO: 1444 LCP1 ADXCRPD.1593.C1_s_at GAAGTAAGCCTCATCATCAGAGCCTTTCCTCAAAACTGGAGTCCCAAATGTCATCAGGNNNN SEQ ID NNNNNNNNNCAGCCACTAAGAACCCCTCTGCTTTTAACTCTAGAATTTGGGCTTGGACCAGA NO: TCTAACATCTTGAATACTCTGCCCTCTAGAGCCTTCAGCCTTAATGGAAGGTT 1445 TAPBPL ADXCRPD.18421.C1_at TTTCTGCTGCTCCAGATAGAGCCAGGCAGAGCAGCAGGCACCAGCCCTCCTGTGTGCCCATG SEQ ID GAGGCTGCTCTCGAGTTCCCTCCTTGCCCACCGCCCGTTCTCCACAGTCCTACGCTGCTTGC NO: GAGGCCCGGCGGAAGAAGGGGGCTCTCCAAGCACACACTGGCAGCCTGCAGCCTTTAGGTTT 1446 CTTCCCCTGTTCCCTGCTGCATCCTCGGGATTTCGCGCACCCCATTAATCTATTCTCGGAGT CGGGTGGGT MDN1 ADXCRPD.8864.C1_s_at AAAGCAGTGCTGAATACTTGAAACTGTGTGCTCTGTTCTACTTAATGTTCTGTCAGAATGTT SEQ ID CTTTTGTAGGCAGTATGTCATGATGTAATCATCTATCTCCTTGTCTGTTTCCAAGTTACACT NO: GTGAAGTCTGCGACCCTTTTGAGGTGGTCATCAAAGACACAGATTCCTTGTTTAACCAAGTG 1455 TCCCAAAGCATGTACCTGAAGTTATATCAT SP110 ADXCRPD.2201.C1_s_at AAGCACTTCAGTGACCAATGACAAGTTAACATCCAAAATGAATGCGGAAGAAGACTCAGAAG SEQ ID AGATGCCCAGCCTCCTCACTAGCACTGTGCAAGTGGCCAGTGACAACCTGATCCCCCAAATA NO: AGAGATAAAGAAGACCCTCAAGAGATGCCCCACTCTCCCTTGGGCTCTATGCCAGAGATAAG 1456 AGAT CXCR4 ADXCRPD.2235.C1_at TGGGATCAGCATCGAATTCCTTTCACCTCCTGGAAATCCATCAAGCCAGGTGTACATTTGAA SEQ ID AACC NO: 1458 CXCR4 ADXCRPD.2235.C1_s_at AGATATATCTGTGACCGCTTCTACCCCAATGACTTGTGGGTGGTTGTGTTCCAGTTTCAGCA SEQ ID CATCATGGTTGGCCTTATCCTGCCTGGTATTGTCATCCTGTCCTGCTATTGCATTATCATCT NO: CCAAGCTGTCACACTCCAAGGGCCACCAGAA 1459 NFATC3 ADXCRPD.9584.C1_at AGCCTATGCTGCTCCTGTTCTTTTGCCAAATCTACCCAAGGCCTGAGGTGGAGGAATGCTAC SEQ ID TTTCCCCACAAATGGTGGGTCCCACTCCTGGCCCCAGACCTGAAGGCTGCAGAGTTGGAAAC NO: CCAAGGTCCAAGGAGAGA 1470 MYB ADXCRPD.10703.C1_s_at AAGCTTCCAGAAGAACAGTCATTTGATGGGTTTGCTCAGGCTCCGCCTACAGCTCAACTCCC SEQ ID TGCCACTGGCCAGCCCACTGTTAACAACGACTATTCCTATTACCACATTTCTGAAGCACAAA NO: ATGTCTCCAGTCATGTTCCATACCCTGTAGCGTTACATGTAAATATAGTCAATGTCCCTCAG 1479 CCA USP7 ADXCRPD.11382.C1_at GAAATACTTGCCTAAGTTTCCCTGATGCTTTCTCCCCAAGCTCCACGGCCTTTTTACATTCT SEQ ID TCTAACAGGTCCCGGACACACCCATGCTTGTCTGGATATAGTGTTATTTCCTAAGTAATGAA NO: AAGATAAAATAAGTGCTTTCAAGAAAGCATAAAAGGTCTGCTACCACAAAGGAAGAGAGGAG 1480 AAAGTTGCATCATTGTTCTCAACTGTCCCCAGCTGGCCCCCATGTTCTTGCTCTCATTCCNC ACCCCAACTCCCTCATCTGTGAATTCACTC BLM ADXCRPD.11385.C1_s_at GGAGAATACAGCTTTTGGCCTACTTTGGTGAAAATGGATTTAATCCTGATTTTTGTAAGAAA SEQ ID CACCCAGATGTTTCTTGTGATAATTGCTGTAAAACAAAGGATTATAAAACAAGAGATGTGAC NO: TGACGATGTGAAAAGTATTGTAAGATTTGTTCAAGAACATAGTTCATCACAAGGAATGAGAA 1481 ACATAAAACATGTAGGTCCTTCTGGAAGATTTACTATGAATATGCTGGTCGACATTTTCTTG GGGAGTAAGAGTGCAAAAATCCAGTCAGGTA HCLS1 ADXCRPD.1749.C1_at ATAAAAACCTCCTTGTTCGCTGCAGCCCCGGGGGGTGTAAGGGGGAAATTGGCGGCCCTGGG SEQ ID CCATACGGAAAACAAGGCGCCGTGACACTCCAACAGAAGATCGGCACCGTCCCATCCACACG NO: GCTGCAAACTTGCGCCAAAATGCATCTAAACCACGAGAACGCCCGGGGGGGATCCACCCCGC 1483 GTGGGCACGCCGCGGGGAGAGAGGGCGAACGCCGAAACCCAGGTGTGGCGAGCAAAGCTACC CCATAAAACCT 41888 ADXCRPD.2412.C1_at GCTTACAGCGGCGATACAGCTCATAGTGCCGGGTGTGGGTCTGCTCCCGCAGATCCTCCATG SEQ ID TTGACCCGAATCAGCATCTCCCGCAGCTTCACAAAGTCGCAGTGGGCCTCGTTTTCAACCTG NO: CACAGTGCCCCAAG GATACTGCCGCGCCCTCATCATCTTGTTGCCTATCTTCAGTTCTTCT 1492 GTGCTGCCAATGACAGCAAACGGCAGGTGGGCGTTCATGGTTCCATTGATCTCTGCCACCGA CTCATCATCTGTAAGGAAACTGATAGATCTGGACTCCGTT NAP1L1 ADXCRPD.3079.C1_s_at TCAAAGATAGAATCCCATTTTTAATGAACTGAAGTAGCAAAATCATCTTTTTCATTCTTTAG SEQ ID GAAATAGCTATTGCCAAAGTGAAGGTGTAGATAATACCTAGTCTTGTTACATAAAGGGGATG NO: TGGTTTGCAGAAGAATTTTCTTTATAAAATTGAAGTTTTAAGGGACGTCAGTG 1494 CD53 ADXCRPD.1819.C1_at GGTTGCTATGCGAAAGCAAGACTGTGGGTTCATTCCATTTTCCTNATATCGNGATCATCACC SEQ ID ATCTGTGTATGTGTGAATGAAGGTTTTGGGGATGTCCTTTTGCCCTGACCCTGAACTGNCAG NO: ATTGACAAACCCAGCAGACCCATAGGGTATTGATCTGCAGNAANTCCTTGGGGTGGAAAGAA 1497 ACTGGTTTCATCTTCG G GAATG CCAAACCATTTTATAG CATG GAG CCCCTACCTGT MSH2 ADXCRPD.1845.C1_at GATGTTCCACATCATTACTGGCCCCAATATGGGAGGTGAATCAACATATATTCGACAAACTG SEQ ID GGGTGAAAGTACTCCTGGCCCAAATTGGGTGTTTTGTGCCCTGTGGAGTCAGCAAAAGTGTC NO: CCATGTGGGACTGCATCTTAACCCCAATAGGGGGCTGGTGACCATTCAATTGGAAAGGGATC 1501 CTCCC FABP5 ADXCRPD.277.C1_x_at GTGTGTTGGATTAATTAGGATCATCCCTTTGGTTAATAAATAAATGTGTTTGTGCTAANNNN SEQ ID NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCNNNNNNNNNNNNNNNNNNNNNNNNN NO: NNNNAATATGTTCGGGCCGCCTCGGGCCCTTCAAAAAACTTTTTCAAGAACCATTTCGTTTT 1504 GGCCCCCGCGGGCCCCAATAGGGTAAAGTGAAAACTTGGCCCATACCTTGTTTTCCCATAGG AAAATCCCCTGGGCCATTGAACAAAGG ARHGAP15 ADXCRPD.9769.C1_at AAAAACATCTTCAGTGCTCCGGTGACAACGTGGATGTCCTCCCACTGGCTGTCGTCCAAATT SEQ ID CAGCTTCTCTTCAGTTTAATGAAGTGACAAATTATTGGCTTGCTCTGGAGGTCAAATGACCA NO: CTGTGAAAAATCTGCAGCTTACTAGGGGTGTCCACAGGTCTCCATCCAGTTCTGATAGAAGG 1508 GCTGGTATTCCAGAAACGACTTGGTTGACAATAAATCTTAACTTCTGTATTGTTGCCAGATT GCCACTAACTCGATATATTCCATCAACATCTAGACCTC PTPN2 ADXCRPD.12103.C1_s_at CGGCCCTTGCGCCTTTCTAGCATAAAGTGGTGTGTCAGAGCCACTGTCTCCACAGAAAGCAC SEQ ID CACGTTTGTTTCATTTGACTTATTTGAACCCGTTTCTCCTGCCTTTGCCTTTTTAAATAAAA NO: ATAGCAAAAATTGATTCAAGTGAATCTATTAGAATTTTCTAAAATGGAGCCCATTTGTCTTT 1509 TCAGTCTTGCAAGTAAAGTCTTTAAAACAATTAAGCCTCCCAATGATTTAACCGTATT PTPN2 ADXCRPD.2533.C1_at CAGTATTACACAGTGGGAGGTCCAAATTGGATTAGACTTTGGCATTGAATTCCAAAGTATTG SEQ ID GTAAGTCTAGCACATACTATAAAGGCTTTGCTAAATTCTGGTGGGTACATTATTTTTAAAAC NO: CTGTCTGTCTGTCGGTATCACACAGAGGTCACTTCTTGAGTAAAATAAGATGACCTTAAGAA 1523 TTCACATAATTCTTGAAGAAGAATATAAGTCACGATGCTTCCACATGAGGCCGCGTCACACC ACCATCGTTTGGAAATCCAGCACCTCAGCCGT P2RX5 ADXCRPD.2544.C1_s_at AGAGTTCCTAGATTACCTCACTGGGAATAGCATTGTGCGTGTCCGGAAAAGGGCTCCATTTG SEQ ID GTTCCAGCCCACTCCCCTCTGCAAGTGCCGCAGCTTCCCTCAGAGCATACTCTCCAGTGGAT NO: CCAAGTACTCTCTCTCCTAAAGACACCACCTTCCTGCCAGCTGTTTGCCCTTAGGCCAGTAC 1524 ACAGAATTAAAGTGGGGGAGATGGCAGACGCTTTCTGGGACCTGCCCAAGATATGTATTCTC TGACACTCTTATTTGGTCAT ALDH5A1 ADXCRPD.1911.C1_at GGGTGTGGCTATGCTCTAATAACATTTTGTTTATGGACACTGAAATCTGAATTTCATAGAAT SEQ ID TTTCAGGTGTCATGAAATATTGTTCTTCTTTTGATTTTCTGCCCAATCATTTGAAAACATAT NO: AAACCATTCTTAGCTCACAGGTTGTATAAAAACAGGTGGCAGGCCAGGTTTGATTCGTGGGC 1528 CATAGTTTGCCAACCCCTGATCTAATGGTCCTTTTCTAGTCCATGTTGTAAAATGTATATAT TTTTAAAATCCCGTTACATATGGCTACTTTA CYFIP2 ADXCRPD.9810.C1_s_at CCATGCCGAGCGCAGGAAGGACTTTGTCTCTGAGGCCTACCTCCTGACCCTTGGCAAGTTCA SEQ ID TCAACATGTTTGCTGTCCTGGATGAGCTAAAGAACATGAAGTGCAGCGTCAAGAATGACCAC NO: TCTGCCTACAAGAGGGCAGCACAGTT 1540 MSH2 ADXCRPD.12253.C1_at CATTTCACGAATAAAAGTTACTACGTGAAAAATCCCAGTAATGGAATGAAGGTAATATTGAT SEQ ID AAGCTATTGTCTGTAATAGTTTATATATTGTTTTATATTAACCCTTTTTCCATAGTGTTAAC NO: TGTCAGTGCCCATGGGCTATCAACTTAATAAGATATGTAGTAATATTGTACTTTGAGGACAT 1544 TGTCAAAGATTTTTATTGTGAAAAATGAGAGCTGTAACTGAGGACTGTTTGCAATTGACATA GGCAATAATAAGTGTTGTACTGGA IGJ ADXCRPD.2619.C1_at GGTACACAAATCTGGTTCTCAATGGTGAGGTGGGATCAGAGATATTCTCCCTGTTGTTCAGA SEQ ID GGAACAATAATTCGGATGTTTCTCTCCACAATGTCCTCATTAGGATCTTCGGAAGAACGGAT NO: GATCCTGGAAGTAATCCGGGCACACTTACATTTGTTGTCAACAAGAACAATCCTTTCATCTT 1546 CTTGGGCTTTCACATGAACAGCCTTAATAAAAACCGCCAGGACTCCCCAGAAAAGCAAATGG TTCTTCATCTTGACTTC UTP3 ADXCRPD.2675.C1_at AGCTTAGGGAAATTTCACAGTTCATTGTGGAGTGTTAAACTTAGAACATGTGTAACTTTTCA SEQ ID CATAAAGAGAATGCATCTTTGACAGTTATCTTATTTGTAAGGCAGCCTATAAAATAGTTCTG NO: AAGTATTTTATTTACCTAACTATAATTATTGGGCCAGATACTTGTTAATAAATGGGCTTAAT 1550 GTTAACATGGATTTCATATGTTCTGTGTGGT RNPS1 ADXCRPD.500.C1_at ATGCATAGATATACACACCACGCCCCCACCGCGATGTTAACGACACCGCGAGATAATACTAT SEQ ID TCCCCCCACACTGCGTCTCTGTTCTGTTTCTNAGCACACCTCTCACCTCTCCTCTTATCTCT NO: GTGGCGGTCGAGAACATTGCACTCACCCCACTATTTATCTCTATTCTTTCTCTATTACTGAC 1561 CAACATATCCTCTGTGCGCACCCTCGCGCGGAAACAACAACATCGTGTACACACCACAAGAA GTAAGCACATGATTGCTAGCCTGGGACACCGCGCCCTCATAATATATA PIM2 ADXCRPD.4065.C1_at AATGTAAATAACTCACGTATAGTGGGGAGGGGAGTTCCAAGTGTGCCCTCCTCTCTTACTCC SEQ ID TGCCTGGATTATTTAAAAAGCCATGTGTGGAAACCCACTATTTAATAAAAGTAATAGAATCT NO: GCAAAGTTGGACGGAGCGAGAATTCGT 1573 PIM2 ADXCRPD.4065.C1_x_at TCCTGAGCCGGGATTGTCCAATTACTAAAATGTAAATAACTCACGTATAGTGGGGAGGGGAG SEQ ID TTCCAAGTGTGCCCTCCTCTCTTACTCCTGCCTGGATTATTTAAAAAGCCATGTGTGGAAAC NO: CCACTATTTAATAAAAGTAATAGAATCTGCAAAGTTGGACGGAGCGAGAATTCGT 1574 GCH1 ADXCRPD.4094.C1_at AAGTCATTACTTTGCATTTACTAATAAGACAACAGCCTGTGGATACATTAGACCTTTATAAG SEQ ID AACACTTCTAGGAAATGTTAGAACAACGAGTCATTAAAAAGGAATATAAATGAGTTCATAAA NO: GATAAATGTATAG CTGACAATTTCTTTG GTCCTCGAAGTCACACTTGTTTTTACTTTAAA 1577 ATGCCAAACATGAGTTGAGTGCTCAGAATTCTACCTATAAATGTCTAAATATTAAGCAGGCT TTF1 ADXCRPD.2906.C1_at AAACCCGCGCTAGGTAAATTCTGCTATCTGGCCGTCAACACGCTGTTTTCACCAGCTCATCT SEQ ID AGTCGCGCCTGAATAGTAGCGCCGCTACCCGCGGGGCCCGCGTCTATTTCTTTTATTAGTCG NO: CCGCCGCGCGGTGTGCATTATATCTCAATCCTTGCGAGTCGCGTGAATGCGGAGCGAATTTG 1598 TGAGNCACGCGAGTGGGCCGCGCCGCACGGGGACGCCTTTCGCTNCCCATCATTCCCACTTT ACGGCCGTCCGGCCCAGCCGGTCGCGTATTACTTGCCGGTGGC LBR ADXCRPD.2923.Cl_at TTAAGACAGCACTCCTTTACAGGGAGTCAGGTTTGGTAAATATAAAGGATACATAAAAAATA SEQ ID CAGTATAAACTGCATAAGCTTAACAGTAGCAAAAACACTGATGAACTTTTAAAAAGTCAAAA NO: ATATATAAAAATATTAGCCTGAAATGGCAAATTTTCAAACACCGATCTGTGTAA 1600 TMPO ADXCRPD.3658.C1_at TTGTTCACAGTGTTGGCACATGGTAAGGGCTAAGACACTTGATTAGCATAATATTCAAAATT SEQ ID AGAAATTGTACACTATTGTACTCTCTTTCAAAAGGCAAACAGCCTAAAACTGTTTGGAAAAA NO: ACAGCTTGTACAGTATATTGTACACTTCCTGTGATAGACTAGTGGACTGATACACCCACTAA 1615 TGCACAGCAGTAATAGTCCACCTCTTTACACANTTATGCATGTTAAGTGACAAAAAAACTCA CTTTAAAAGGCCAAATGATAAAAACATCAGCCTTGAGGCTCTTCGATATAGA IGJ ADXCRPD.4305.C1_at GGCAATTTCTTACACTAACCTGATTATGAAAAAAAGAAGTCTGTATCATCTGCTTCCAAGTC SEQ ID TGTTATGTCCAAATATATTTTAATTATGCATTTATTTTGCTACTTTTATAAATATTAGAGAT NO: TTCACCTTAAATTATTTTTGTAACTAGTTCTAGAACATGTTTTCCAATTATTATTTTTCTAA 1619 TGGAGACATATAATTGACCTATGTTTATGCATATATGTTCTCTACACAGTGAAACTTTTTTT AAAAAGAATAGTAAAGAAAATGCGGAAGCTCTGGCTCTCCAAG ICAM2 ADXCRPD.4332.C1_at GAGGCTGCCCCACCGTTCCGGCCATAGCAACCATGAGTGGCATGGCCCACACCACGGTGG SEQ ID NO: 1622 ICAM2 ADXCRPD.4332.C1_s_at TGTCGGTGTTGCTGTCCCTGTTCGTGACATCTGTCCTGCTCTGCTTCATCTTCGGCCAGCAC SEQ ID TTGCGCCAGCAGCGGATGGGCACCTACGGGGTGCGAGCGGCTTGGAGGAGGCTGCCCCACCG NO: TTCCGGCCATAGCAACCATGAGTGGCATGGCCCACACCACGGTGGTCACTGGAACTCAGTGT 1623 GACTCCTCAGGGTTGAGGTCCAGCCCTGGCTGAAGGACTGTGAC TMEM177 ADXCRPD.4336.C1_at TGCCATTGAGTCTGGAGGGCCCTGTTGGAGCCTTTGGACCTATAGCTCAAGGCCAGAAAAAT SEQ ID CACTGGCTTTGGAATTAAATAGCTTAGATTGTACTATAACCACTACTTATGAACTCAGGGAC NO: TATGAGGGACTATTCAGGGGCTATGAATCTGAGCCTTTGTTTCTTGAACTGTAAAGTGGAGA 1624 TGATGTAAACCGCCTTGCAAGATTGTAGAGTTGGGTAAGGTCATGAACATAAGGGCCTGGCA CAAAGGGTGCACTGTAAATAAACAGACATCCCTCCTTA NUP210 ADXCRPD.12713.C1_at ATCCCTGTTTGTCTGCAGCTTTATATATGAGTTGGGCGACATTAATATTTGTTCTGCTTCTA SEQ ID TTTCAGGGTTGAGCAGCTGCAGCTTCTCAAACACCTGGACTTGGATCTCATCCGAGAGTTCT NO: CTGGCCAGGCCATACAGCTGCCCCGATGTGGGGTCCACAGCCTTGACCACCACCCTCAGCCC 1628 GGTCCGGCCTTTTACCCGCCGAGCACGTTCATGGCAAAGTTGTATCTGTGACGGGAGTCGGA TCACGCCTCGTGT CD53 ADXCRPD.3701.C1_at TGGACCATTGTCACAACCCTCTGTTTCTCTTTGACTAAGTGCCCTGGCTACAGGAATTACAC SEQ ID AGTTCTCTTTCTCCAAAGGGCAAGATCTCATTTCAATTTCTTTATTAGAGGGCCTTATTGAT NO: GTGTTCTAAGTCTTTCCAGAAAAAAACTATCCAGTGATTTATATCCTGATTTCAACCAGTCA 1629 CTTAGCTGATAATCACAGTAA IQGAP2 ADXCRPD.12735.C1_at CCACGCCTGTGTACATGTGGTTTCATAAAACATCCTTAAGCATGAGCTAGACATTAAACAGT SEQ ID 2 CTTGGAGATTCTAGTTCAGAATTTACCTCAAACGTGTGAATTATGGAAATTCATGGTTCATC NO: ACAGATGGTTGGGATGTTGCCAAGATACATCCTTTAGCACGCCTCTGTTTGCTTTATGTGAA 1631 CATTAATAACTCTGTTCCAGGAG ALDH5A1 ADXCRPD.14052.C1_at TTCAGCTGTGATTATTCTGGCAAGGTCATCCTTATTTTGTATCATTAAATTGTACCACTTCC SEQ ID GAAGTAATGAACTCCTCTCCTTGGCGGAGACCTCCCTCCAGCGGCAGAAAGCCTCGTAGGCA NO: GCGCGCACGGCGGCGCGGGCCTCTCGCACCCCACAAACGCCCACCATGCCCAGAGCGGCGCC 1636 GCTGGCAGGAGTCTTGCACG ALDH5A1 ADXCRPD.14052.C1_x_at AGAGAACCACTCTAGGAAAAAGGCGGAATAGAGAATTTCTCCATGTGCCTCCTTCAGTGGCT SEQ ID TTCCACTTTCAGCTGTGATTATTCTGGCAAGGTCATCCTTATTTTGTATCATTAAATTGTAC NO: CACTTCCGAAGTAATGAACTCCTCTCCTTGGCGGAGACCTCCCTCCAGCGGCAGAAAGCCTC 1637 GTAGGCAGCGCGCACGGCGGCGCGGGCCTCTCGCACCCCACAAACGCCCACCATGCCCAGAG CGGCGCCGCTGGCAGGAGTCTTGCACG PTPRCAP ADXCRPD.5068.C1_at CCCAACCACAGGCATCAGGCAACCATTTGAAATAAAAC SEQ ID NO: 1645 PTPRCAP ADXCRPD.5068.C1_x_at ACCACAGGCATCAGGCAACCATTTGAAATAAAACTCCTTCAGCCTG SEQ ID NO: 1646 LBR ADXCRPD.5090.C1_at AAACATCAATAGCATTCTTCACAGTACATTTATATTAAGACTGTCTTCTGTTTTCAGGATTA SEQ ID ACGGGTTGAAAATTTCCCATTAAAATGCAAATTCTCACATCCTTACTTGTATTTTTCCTATG NO: TTAACTGTAAGTTAATACAAGTAAACACGGCTATATTAAAAGATCAACTACTCGGCTCCATA 1650 GTCCTGACTCAA GCN1L1 ADXCRPD.13574.C1_at AAGCCTTAGGTTGGTAATCCGGCTGAACTCGGCTTGACGGCCTGAGGCCC SEQ ID NO: 1664 GCN1L1 ADXCRPD.13574.C1_s_at GATGCCCTAAATGCCATCACTAAGAAGCTGGATGCTGGCAACCAGTTGGCACTCATTGAAGA SEQ ID GCTGCACAAGGAAATCCGGCTCATAGGGAACGAGAGCAAAGGCGAGCATGTGCCAGGATTCT NO: GCCTCCCGAAGAAGGGAGTGACCTCCATCCTTCCAGTGTTGCGGGAAGGAGTCCTGACTGGC 1665 AGCCCTGAGCAGAAGGAGGAGGCAGCCAAAGCCTTA ALDH5A1 ADXCRPD.13575.C1_at TTATAACTCTGGATTACCGATGCTGAGATGTGTGCAGGAATACTTCCAAATAAATTTTTAAC SEQ ID ATTGTAAGCCAGTAGATTCTTTGGCTGGGTGGCAAATTTTGAGTCTTCTTGCATATTTGGCT NO: CATGGGTTCATAAATTGAGGCCAGAGACTCATTGTATATCCTTGATCAATTTTCTAATTAAA 1666 GGAAATAGCTTATTGTTTAGTAAAATGGCC LBR ADXCRPD.12940.C1_at GCCAGTTCTTTTACAACGTATGCTTCTTCCTTAGAATCTATTTCTTTTAATCTATGACTTAT SEQ ID TCTCTTCTTGGACGAAGGCTATATCTGTGTTGCTATGTAACTGCTTGACTTGTGACAAAACT NO: GAATTTATCCTGTGTATTTATATGAGGTGCGTCATTTCTCATCAATATGACTCAGGCATCCC 1673 CATTAAATCTGACTAGATGCTATTTCACAAATGGCTTCAGAATCAGCGGAGTCAATTTAACT TCCACTTCCCTCCTTGCTTCCTTAATGTCGGCCTGATGGTAGCAAGACTGCG TMPO ADXCRPD.12957.C1_at TAAACATGCAAACTCACTACCAAATTGGCTTATAGTAATATTAGGCCTTAGCAATTCCATTA SEQ ID AATTAAGAGCAACTCATTATTGGAGAACACTTTCTAAGTTGAACTGTAATCATACAAACCGC NO: ACAGCCAAGCAAGTAACTTAAAGACATTGTTGTTAAAATAGTCCATTTTGGATTACCTATCT 1676 AAA THUMPD1 ADXCRAD_BP377292_s_at TGAAAAGTAGCAGCTTCTCTATCCAGGATGATGAGTCAACAGGTTTCACTAATATTTGTCAT SEQ ID GCTGTAGCATTTGTAAGATTTGTAAATGATGAAATTCAAAGAAAACTTTTTCTATTGCTAGG NO: AGCCTGCCAGAACAAAGGCCAATATATAATGTTGTGACATCATATCTGATAACCAGAGGTCT 1677 GGTATCTACACTCCTGGTGCCCCATCAGTGGTTGTCTCCATAAGTCATTTTGCGT FBXL14 ADXCRPD.4724.C1_s_at GGAGGAATAGATGACTTTCTTTCTTTTGGTGGGGGTTGGGACTTGTGGCTTTAAAGAAATCA SEQ ID CTTCTGAGTAGGATGTATATTTTCGTTGGATTTTTGTTGTTATTTCTTTAGAACCCTCCACA NO: GCAACATGCAAGACCATGGAGTTAAAGAAACCCAGAGACCTTTATCAATTAATTGTACTGTT 1696 TGTGAAT UTP3 ADXCRPD.6075.C1_at AAAATACTACGTTCTAGCTGCTTAAACAGTCTGTATTTTCCACATTATGATGGATTCAAAGC SEQ ID AAATAAGAGTCACACTTCAAAGTCAGAAGTTGCATTCCTCTTAAAGGATATTTGTACTCGGC NO: TGCTACTATAAGACAAAGGTTAACTTGACAGGCTCAATGTCTCTGTTATATATTGTGGAAAA 1703 ATTACCTAAAATAGCTATCATTTATTAAATTTCTATTTTCTGTTAGGTGCTTTACAAATGCC A EZH2 ADXCRPD.13819.C1_at GTGTTTGACACCGAGAATTTGCTTCAGAGGAGCTCGAAGTTTCATCTTTCTTCTCTTCTTCT SEQ ID TCTTTATCATTGTTCTCTCCCCCCGTTTCAGTCCCTGCTTCCCTATCACTGTCTGTATCCTT NO: TGATTCCAGCACATTAATGGTGGGGGTGCTGGGCCTGCTACTGTTATTGGGAAGCCGTCCTC 1705 TTCTGCGGCCTCCTGGACGTTTTGGTGGGGTCTTTATCCGCTCAGCGGTGAGAGCAGCAGCA AACTCCTTTGCTCCCTCCAAATGCTGGTAACACTGT HNRNPA2B1 ADXCRAD_C N402594_s_at GAAGAAGTGGTCAACCACAGAGTCTTCAAGAAATAAGAAATTCTGTACCATCTGAAAGTAGT SEQ ID TCTTGTTGGTGCCTTCATTTAAA NO: 1709 LBR ADXCRPD.13860.C1_at AATGAAGTGTCTTGGCCAATGGCTTCTCTAATTATTGTTCTGAAACTTTGTGGTTATGTAAT SEQ ID CTTCCGAGGTGCAAATTCTCAGAAAAATGCATTCCGGAAAAATCCCAGTGATCCAAAGCTTG NO: CACATTTAAAAACCATTCATACTTCAACGGGAAAAAATCTTCTAGTTTCTGGATGGTGGGGC 1711 TTTGTTCGCCACCCCAATTACTTGGGTGATCTCATCATGGNCTTGGCGTGGTCCCTCCCATG TGGTTTTAACCACATTCTGCCTTAT PCCB ADXCRPD.6197.C1_at GAATCTCCAAAGAGAATAGCCGGCCCGAAAAGGAG SEQ ID NO: 1720 PCCB ADXCRAD_B P253154_s_at GCTGCTCAGGCAGAGTACATCGAGAAGTTTGCCAACCCTTTCCCTGCAGCAGTGCGAGGGTT SEQ ID TGTGGATGACATCATCCAACCTTCTTCCACACGTGCCCGAATCTGCTGTGACCTGGATGTCT NO: TGGCCAGCAAGAAGGTACAACGTCCTTGGAGAAAACATGCAAATATTCCATTGTAAACAAAT 1721 CAAAGGAAAAGAAACCAAGAACTGAATTACTGTCTGCCCATTCACATCCCATTCCTGCCTTT TGCAATCATGAAA IQGAP2 ADXCRPD.14593.C1_at CCACTTCTAATGCAATACATATCCCGGAGTGTGCT SEQ ID NO: 1725 IQGAP2 ADXCRPD.14593.Cl_s_at GCACTACCAGGATGTTTTATACCATGCTAAATCACAGAAACTCGGAGACTCTGAGAGTGTTT SEQ ID CCAAAGTGCTTTGGCTGGATGAGATACAGCAAGCCGTCGATGAGGCCAACGTGGACGAGGAC NO: AGAGCAAAACAATGGGTTACTCTGGTGGTTGATGTTAATCAGTGTTTGGAAGGAAAAAAATC 1726 AAGTGATATTTTGTCTGTATTGAAGTCTTCCACTT TPT1 ADXCRPD.14624.C1_at CCAGCTGGAGTTTTTGGGACGCTTTTGTGGGGGCACCGCTGAGTCCGGATAGTGGGACCCAA SEQ ID GTCGTCCTGCTCGGCCCCTGGGGAATAATCGTGTGGGGCGCAAGGTCTGTGGGAAGGGACTT NO: GGAGAGGAGGGAAGATGTCGCGGGAGTCTGCACAGGGTTTCCATGTGTTCCAATTCTTCGTC 1733 CCATAATTCAAAGCTCGTGGCATTCTGTGGCCGACCGCTACCGAGCTAGCTCTTCCCTTTAC TATTTCGCACTTGGTCTTGGAAAAGAT 41888 ADXCRPD.5611.C1_x_at GAAAAACCCTTGTGGGCACCAATGAAATAGAGGGGGCTTCGGGAGATTTTNNNNNNNNNAAC SEQ ID ATAAAAAAAGAACACGCCCCCCCGCGGGGGGCGAAAACGCCCAAGGGCGGCTTTTTCTCAGT NO: AAAACAAAACTCCCCCCAAAACGTGGGAAGTTTTCTCTCTCGGGAGGGCCCTTATTTGACCC 1734 GGGGGCGTTCTCTATCCCCAACCACGTGGGCGGAGGCTCCCCTAAGGAGAGCGCGCGTCCTC TCGATAAATATTGCGCGACGACGTGTTTCAGCG CALML4 ADXCRAD_BX431388_s_at GAAGCAGATATCGAACCCAATGGCAAAGTGAAGTATGATGAATTTATCCACAAGATCACCCT SEQ ID TCCTGGACGGGACTATTGAAGGAGGAGAATGGGAGAGCCTCCCCTGGGCCTGAAAACTTGGA NO: GCAATTAATTTTTTTTAAAAAGTGTTCTTTTCACTTGGGAGAGATGGCAAACACAGTGGCAA 1753 GACAACATTACCCAACTATAGAAGAGAGGCTAACTAGCAACAATAATAGATGATTTCAGCCA TGGTATGAGTAGATCTTTAA ATHL1 ADXCRAD_AJ708476_s_at AGTGGGATGGCTCTCTTCCCTCAGCCACGCCGCTTGTGAGGACAGAGGTGGGGGAGTGGGAA SEQ ID GTGGGAAGTCACCAGAGAACAGGAGAGGGATTTGAGGGCGCGACCCCAGCGCTCTCCACGGA NO: CCAGCCAGAGGGACTGGAGCCAGGTGTGCATGGGTTCAAGGCCCTGGCCCTGCCCAGCCTCT 1756 GTCTTGGGAGCTCAGCCCCAGGGTTCGGTCGTCAGCAGTTTCCCAAGAACAAGATGTGATGG CATCTGCTGCTGAAACCCTGATGAGGACCAGGCCCC LRMP ADXCRPD.6445.C1_at AGTCTGCCTATGATCTTTGAATGAGCTTTTTAAGGAAGAATATTATATATTGTTTGCTAAAG SEQ ID CCTATTGAAATAAAG NO: 1757 BCL11A ADXCRPD.15478.C1_at CCATCCCACCACATCATGTAAAGTGTTTCTAGGCTTCTCTATATAATACCCAGAAATGTGAG SEQ ID CATACAAAAAGTACAAGGATGTGAAGGTTATCAACCAGAGAGCAAATTGGTCAATGAGGCAA NO: ATCATCACATATGTAAAGAAAACAGTCTTCCTGGCATAACTCCAGAGAACACACACACACAT 1758 ATACCCATGCACACACCCACAGCAACAAATGTGTCTGGTCTGGTAAGTTTA HCLS1 ADXCRPD.6475.C1_s_at GTCCTCTCTATCCTGGATGAGCTCATGAACATTTCTCTTGTGTTCCTGACTCCTTCCCAATG SEQ ID AACACCTCTCTGCCACCCCAAGCTCTGCTCTCCTCCTCTGTGAGCTCTGGGCTTCCCAGTTT GTTTACC NO: CGGGAAAGTACGTCTAGATTGTGTGGTTTGCCTCATTGTGCTATTTGCCCACTTTCCTTCCC 1760 TGAAGAAATATCTGTGAACCTTCTTTCTG WDR59 ADXCRPD.15558.C1_s_at CAGTGTTACCCTGTAAGGTGTTAGCCTTAAACCACCGAGCAGCGTTCTCTTGATGCCAGTGC SEQ ID AGAGACCAGAGTCAGATGCCCGAGGACAGTGGGTAGGAATTTCATCAACAAATGGACCTATG NO: GCATCATGGCTTTAGAAGCTGGTACATTTACTGAGCTGATGGACAGTGGCCTTCTAAAATAT 1764 GACACTTAAATTGTAAATATGCACTGTACTTAAGGATTCTTAAGATGTATTTTTTTGTTATT TCTCCTCCAGCTGCTATCCCTTGGCTAATAAA ATP2A3 ADXCRPD.5908.C1_at ACATATAAAATCATCAGTCTGCACACGCTCTAGGAGGGGCCAAGACATAGGGACAATCCTTG SEQ ID GTGCAGGTTTCTGCTACCCCTCGCTAGTTTTTGCCAAAGTAGCAAAAGCTGAGTTAAGAGAA NO: AAATTCTGTCCATCAGAGGCCATCTTCCTCTCATCTGATATGACGTGTTCCTCCAGCAGGGA 1765 GGGAGGGAGAGCGGGTGCCCTGGGGAATCAGCCATCCTTAGTGACATCCTTTCGGCTCATGG GTGTCGTG CHD7 ADXCRPD.14939.C1_at TGCTGGTGCATTAGTCCTTGACCACTGTTTGATGGGAATCCTACAGCATTGGGGTATCTTGG SEQ ID TACGGACTGATTCATTGGAGTATTATTTGTAAGGCCTAAATTTTGATTCATCCCTGTATTGT NO: TAACTAATCCCTGATTTAGGTTACTGTAAGGATATCGAGAATACTGCCCTGAGTTGTTTATA 1766 GTAGGAGAGGGGACTGTCTGGCTCCGAGAACTAAAGTTAAGGGTTTGCGGCCTAACAGCCCC TTGTTGGGGAGGATTCGGGGAGAATCTGGGACTGTGGGCAACGGATTC NUP210 ADXCRPD.7334.C1_at ACTGAAGTCTGTTCACAGTGGCCCATGGTTGGGCAGCAGCCCTGGGTGAGCTCCTGTGTTCT SEQ ID CCAGCCTCTCGCTCACCCAGGGCTTGGCTATCCTGGCCTCCAGGTGCTGGTTCCTGAGGCTT NO: CCCTTGCGGCAGTGGCGCAGATACAGGGACACTCATGTCCCATTGCTCCTCAGAAGTCCTAG 1781 CAGCAGCCAGACTAG SKAP1 ADXCRPD.16383.C1_at CAGAAGTTCCAGACCCGGTGGACCACCTGGTGAGACCCCTGTCTCTTTAAAAGNNNNNNNNN SEQ ID NNNNGGAAGACAATTTATTTTAAAAACATCTGAGAATCATTACTGCTTTTATAATATTTAAA NO: TTTTCTACATGAATTAAATAGCCGAAGTACATAGTTATCTATCATTCATCTATCCAGTAAAA 1782 TGTTATGTATTTATGATGCACCAGCATTATAACTAACTCTGAGATCAG MDN1 ADXCRPD.16426.C1_s_at GAAAGAAGCCGAGAGTCTACCATTCATACAGCTCATCAATTCCTCATGGACACGATCTTCCA SEQ ID GCCCTTTTTAAAAGATGTCAATGAGCTAAGACAGGAGCTGGAGAGACAGCTGGAAATGTGGC NO: AGCCACGTGAATCTGGAAACCCAGAGGAGGAGAAGGTTGGAGCTGAGATGTGGCAGAGTTAC 1793 CTGATCTTAACAGCGCCTCTTTCAAAACGGTTATGTGAAGAGCTTCGTCTCATATTAGAGC USP7 ADXCRPD.16454.C1_at GTCTGTCTGGATAAAAGCGTGGCATCACCATAATCTTCCATGGCAGATTTCGCACAAAACAC SEQ ID GGAGGGCTAAGGACCGACTCACTCAGTCTGCTGAAGCGCTCCACAGTGAACTGAAAGGCTGC NO: CTCGGAGCGCCAACTGGTGTCATCCTCCATGTCCTCCTCCGCGGTGTTGTGTCCATCACTCA 1794 GGGCCACATTCCCATTGATCACAGGGTTCTGAGTAATTCTTGGTGGCTCATCATGTATCTCC CG NUP210 ADXCRPD.15803.C1_at ACCTTACTCCCACGATCACTTACAACCCCACGATCACATACACCTTCATCTCACCGAAATGG SEQ ID AGTGGGTTCTGCACATCATGTGCCCGGATCACACTGAACCCGATGTCACTGCCTGTGGTCAT NO: CACGCCCTTGACAGTAACTGTGGCAACCAGGTGGCTTGACGAAGACCAGCTGAAGTTCCCAC 1795 TGCCACCGTGGGCCCTTATTGTGTACTGATAGGCGCCCGTCTTTGGTTGCCACGGAAATGTC AAGATGCTGGGATACAGGGT NUP210 ADXCRPD.15803.C1_s_at CACCTTCATCTCACCGAAATGGAGTGGGTTCTGCACATCATGTGCCCGGATCACACTGAACC SEQ ID CGATGTCACTGCCTGTGGTCATCACGCCCTTGACAGTAACTGTGGCAACCAGGTGGCTTGAC NO: GAAGACCAGCTGAAGTTCCCACTGCCACCGTG 1796 TFB1M ADXCRPD.7488.C1_at GTGATGAAGACCCACAACTCTTTGCATATAATTTCAGAGAAGAACTCAAGCGAAGAAAAAGC SEQ ID AAAAATGAAGAAAAAGAAGAGGATGACGCAGAGAATTACAGACTCTAGCTGCTGCCTGGGGG NO: CGAGCAGCCTACCAGATGTCGATTTGCACTACGTGGAGCTTCTTATATAGGTACTCTTTTGT 1800 CTTTACAGAATGACGATACAAATGCCAATGACCAGATGTGACTTATTTTCCTTTTACTATAC AGCTTGGCAG TAPBPL ADXCRPD.6849.C1_s_at TTCAGAGACGGCAAGCACCTACAGGACTTGGGCTGCTTCAGGCTGAACGCTGGGAGACCACT SEQ ID TCCTGTGCTGACACACAGAGCTCCCATCTCCATGAAGACCGCACAGCGCGTGTAAGCCAGCC NO: CAGCTGACCTAAAGCGACATGAGACTACTAGAAAGAAACGACACC 1803 MYC ADXCRPD.8111.C1_at CAGTGTCCGTCTCCGGCTGTCAGAAATGCGGTGAGCCGAAATTTAAATGCCCTCCCGGAGAC SEQ ID GGGGACAAGTCAGCGGCTGCGGAGCGATCTGGCTCACACAGGCGATATGCGGTCCCTACTCC NO: AAGGAGCTCAGGATGCAAGGGGCTTTCTGCCCACCGCAAAGCAACCCCCAGCCCCCCAAAAC 1806 CCAGAGAGCAATTAACACAATAAAGCAGGAATGTCCGACCGGCCGGGAGTCAGCGTGAATAT ATTCATAAGGCAGAAATCTCGAAAGGGTAGTCTT NUP210 ADXCRPD.15917.C1_at GCCTGACAGGTCACAAGGATCCAGTGTTGCTGATAATTCCGGGAGGAATGGGGGGCAAAGAG SEQ ID AGCCAGGCCGATGCTGTCAGTGTCCTCAGCGGCGACGTTCTGGAAGAATTAGGACGGCTCGA NO: GGATCCAAGGTCTGGGACCTCCTTCAAACAGCATCTCCTTTGAGGAGCCCAGGGTTACCAAG 1813 GCAACAGAGGAGGGATCCACAGCCTTGAGGGGCAGGTAGGCAGCAATGGTGATCTTGGCACT CAGGTGGACGTGGCCGTGTCTGTAGCTCACAAGACGCGTGGTA CXCR4 ADXCRPD.7562.C1_s_at GTATGTCTCGTGGTAGGACTGTAGAAAAGGGAACTGAACATTCCAGAGCGTGTAGTGAATCA SEQ ID CGTAAAGCTAGAAATGATCCCCAGCTGTTTATGCATAGATAATCTCTCCATTCCCGTGGAAC NO: GTTTTTCCTGTTCTTAAGACGTGATTTTGCTGTAGAAGATGGCACTTATAACCAAAGCCCAA 1814 AGTGGTATAGAAATGCTGGTTTTTCAGTTTTCAGGAGTGGGTTGATTTCAGCACCTACAGTG TACAGTCTTGTA LGALS9 ADXCRPD.6993.C1_at AAGATGAAGCCCCATGCTCAGTCCCCTCCCATCCCCCACGCAGCTCCACCCCAGTCCCAAGC SEQ ID CACCAGCTGTCTGCTCCTGGTGGGAGGTGGCCTCCTCAGCCCCTCCTCTCTGACCTTTAACC NO: TCACTCTCACCTTGCACCGTGCACCAACCCTTCACCCCTCCTGGAAAGCAGGCCTGATGGCT 1820 TCCCACTGGCCTCCACCACCTGACCAGAGTGTTCTCTTCAGAGGACTGGCTCCTTTCCCAGT GTCCTTAAAATAAAGAAATGAAAATGCTTGTTGGCACAAAAA LGALS9 ADXCRPD.6993.C1_x_at AAGATGAAGCCCCATGCTCAGTCCCCTCCCATCCCCCACGCAGCTCCACCCCAGTCCCAAGC SEQ ID CACCAGCTGTCTGCTCCTGGTGGGAGGTGGCCTCCTCAGCCCCTCCTCTCTGACCTTTAACC NO: TCACTCTCACCTTGCACCGTGCACCAACCCTTCACCCCTCCTGGAAAGCAGGCCTGATGGCT 1821 TCCCACTGGCCTCCACCACCTGACCAGAGTGTTCTCTTCAGAGGACTGGCTCCTTTCCCAGT GTCCTTAAAATAAAGAAATGAAAATGCTTGTTGGCACAAA PPRC1 ADXCRPD.16668.C1_at AGGGCTTCACTGCAGAGCTGTCTTCTTGGCTGGGGCTGGTGGGATGACAAGACAAGGGATGT SEQ ID CTGCCAGCCCTGTGGGAGTCTCTGGAAGGCTAGGCCACTTCCCAGTTGGGGGCTGTGGACTT NO: CTCTCTTCTGTTTCTGCTTGGCGTTGCTGCCTTCGTCGCCGGTACTCAGATAAGCTGAGAGG 1832 CCGAGGTCTGGCTTCATGGGTTGTAGCACTGGTACCACTTTCAATTTTCA ALDH5A1 ADXCRPD.1124.C1_at TAAATTTCTTACCACACTCATTCCCAAGTTTTATCCCACAAAGTATAGCATGAAACAATGAC SEQ ID AACATACATATTATTCAAGTAAAATGCTATTTAAAATAGCTGCACACAGGTAATTAAAACAC NO: CTAGGATCCAGTTTTTAGAGGAAAAAGNCATGTGGCACAATTNCAAGTTCATAAATTGAGTT 1865 AACAGTAAAACAGATTTGCTCACATTTGCTTCTGATCTTTAT MFNG ADXCRPD.17460.C1_x_at TGGCAATTGGCACTGAAGGCACCCAAGCCCCTGGAGCCTTTCTTGCGGTTAGGGCTAACATG SEQ ID GACCAGCTTTGGCAGAGGAACTAAGCAATCCAATAAGATGTTCTTGGAAAGTTTTGAGCCAC NO: TCCCATCTTCTGGCAAAATGTGGGTTGAAGGCGGATCT 1873 NUP210 ADXCRPD.9121.C1_at TGCCTTGCATATTACTTGAGCTTAAACTGACAACCTGGATGTAAATAGGAGCCTTTCTA SEQ ID NO: 1884 NUP210 ADXCRAD_CX756211_s_at TTGGAAAAGTCCTCTCTTCCCAGCTCCTGATTCTGGATCTGAGATTCTCAGATCACAGGCCC SEQ ID CTGTGCTCCAGGCCGAGGCTGGGCCACCCTCAGGGAGATCCAGAGACTCATGCCCATGGCCA NO: TCCATGCGTGGACGCTGTGTGGAGAGTCCAGGATGACGGGATCCCGCACAAGCTCCCTTCAG 1885 TCCTTCAG EWSR1 ADXCRPD.18189.C1_x_at AATGGGAACCCCTTGTGAGCATGCTCAGTATCATTGTGGAGAACCAAGAGGGCCTCTTAACT SEQ ID GTAACAATGTTCATGGTTGTGATG NO: 1890 UBE2L6 ADXCRPD.250.C1_at TGCCCTTAACCCGATTTGGCCATTCCCCTCTCTCCCCCGTACTATACACCCCCGCCCCGCCT SEQ ID TCCTTCCCGCCTTTGTGCGCCTGTCCGATCATANTTTCCGCCCATGGTCCACGTTCTCCGCC NO: GCGTAACCTATATCCTGGATTCTCTTCCCGCCCCGCGTGTGCTACCCCCTTATTGCCATTTT 1893 CCCGTTACGCGGAGTTCGCCCGAGGCCCGGGGCTTTGTCGCCGCGTACTTTAGGCCCCGCCC CGCCTAAGTTCCGCCTTCATTATACCGCGCTGTG REPIN1 ADXCRPD.869.C1_at ACATCTGCCGCTAACCGTGAAACACCACCACCCGTGGTTCGCCCCAGTTCGCCACCTCCCGC SEQ ID CCTTTTGCCTCCACGCGCTGTACCCACGCCGTGTGGCGGAACAAACCTCGCCGACATTGACA NO: CAAAGTGCCTCCCTCTTGTTGATCNCTCCCACGCGCCGGACAAACTAGCCTCGCCCCCAGTG 1901 AACATCCAGGCCCCGCAGGGCGGATCATGGACCATATACCTTCTCTGCATCACCGGCCTCCC TATAGACACACACTCCCGCTCTGCTGAGTGATATACACGCCCGCCAGGG NAP1L1 ADXCRPD.367.C1_s_at AGTGAAGTTCTCAGATGCTGGCCAGCCTATGAGTTTTGTCTTAGAATTTCACTTTGAACCCA SEQ ID ATGAATATTTTACAAATGAAGTGCTGACAAAGACATACAGGATGAGGTCAGAACCAGATGAT NO: TCTGATCCCTTTTCTTTTGATGGACCAGAAATTATGGGTTGTAC 1910 PIM2 ADXCRPD.11037.C1_at GCTGGGAAGTGGAGCTCAGCTTCCAGAATCTCCTGGTCCCTCTCAAAGGGAATGTCCCCACA SEQ ID CACCATGTCATAGAGGAGGATGCCCAGTGACCAGACAGTGGCCGGGAGTGCATGGTACTGGT NO: GTCGAGAGATCCACTCTGGGGGGCTGTACACCCTTGTCCCATCAAAGTCAGTGTAGGGTTCA 1912 TCATGAAGCAGGGCACCAGAACCAAAATCAATGAGTTTGGCACAGCCACGGCGTAGGTCTAT CAGGATGTTCTCAT TOP1 ADXCRPD.5549.C2_at AGAAGAGCGCTATCCTGAAGGCATCAAGTGGAAATTCCTAGAACATAAAGGTCCAGTATTTG SEQ ID CCCCACCATATGAGCCTCTTCCAGAGAATGTCAAGTTTTATTATGATGGTAAAGTCATGAAG NO: CTGAGCCCCAAAGCAGAGGAAGTAGCTACGTTCTTTGCAAAAATGCTCGACCATGAATATAC 1913 TACCAAGGAAATATTTAGGAAAAATTTCTTTACAAGACTGGAGAAAGGAAATGACTAATGAA GAGAAGAATATTATCACCACCTAAGCAATGTGATTTAACCAGA USP7 ADXCRPD.949.C1_s_at CTGCAAGTGAATTTCACTGATGTTGATATTCATTGTGTGTAGTTTTATTTCGGTCCCAGCCC SEQ ID CGTTTCCTTTTATTTTGGAGCTAATGCCAGCTGCGTGTCTAGTTTTGAGTGCAGTAAAATAG NO: AATCAGCAAATCACTCTTATTTTTCATCCTTTTCCGGTATTTTTTGGGTTGTTTCTGTGGGA 1919 GCAGTGTACACCAACTCTTCCTGTATATTGCCTT ANP32A ADXCRPD.232.C2_s_at AGCTTCATTTTTGTTACCTGATAGAATAGCTTTTCTTATGAGATATATATAATGTGATACTA SEQ ID TGTTTGGATATTTTTGGTCTTAAAGCAAGACTCAGTGGTGTATCTTCATTAAAAGCTTCCTT NO: TAAAAAAGTTACAGAGTTACTAAAAAAACAAGTACCCAAACAATCAAGTTGGGCCAACCTTG 1921 GAACCTTGTTTTGAATATCTTTCATTGTTTTGTTTGTCGTATTGTAAAAAGAATGTATGGTT GAAAACTCAGGAA AQP3 ADXCRPDRC.2086.C1_at GCCCCAGCCTTAGGTTTGGAGCTCTGGATGACATACATAAGTAGGAGCAGTGGGAACTGTTT SEQ ID CTGTCATAATGGAAGGCTGAAAGCGTGGAGTGAACTCAGGTCCTACAGTTCATGGGTGGCTT NO: TTGGTTGGTCCTGGCCTTTACGGGAAGGAAGCAAAGCTATACCGCCCTAAGGGA 1926 TAPBPL ADXCRPDRC.18421.C1_at TCCAGATGACTGAGACCACGTGTTCAGACAGCAGCGTTGGTTCACTGGCCAACGTGCAGGTC SEQ ID TCTGGAGGGGGACCTAGCTTCTCCTTGTGTGATGAACGACTCCCAGGGTCGCCAAGAATGAG NO: GCGCTCTGGCACCCGACCGCTGAACTTGCCACTTGAGGCCCCAGGGAGACTGTGCGAACTTG 1934 CAGTGAAGTTCCAGGTGATGACACATGACCAATCACTGAGACTCCTGCTGGGGTCCTCAGTC TCCTTGGACCTGTGGGTTCTCCATGGACACGG NFATC3 ADXCRPDRC.9584.C1_at GGATACTTTTATATGATGGGTGCTTTGAGTGTGAATGCAGCAGGCTCTCTTGTTTCCGAGGT SEQ ID GCTGCTTTTGCAGGTGACCTGGTTACTTAGCTAGGATTGGTGATTTGTACTGCTTTATGG NO: 1939 USP7 ADXCRPDRC.11382.C1_at AAGTATTTCTTGAGCCCAATTGTGGACGTTCAGTTAGGGGTGGCAGTTAACGCTGACCTCTG SEQ ID CAGTTGCGTTGGTGGAAATCACCCAGCTGGGATCCATGCGCGTCATTCCCAGACTCAGTGGG NO: GTGTGCCTCCATTGCAAAGACAGTTGCACAGAAGCTCAACACAGACCCATTGTTGCTCCAGT 1940 TTTTCAAGTCTCAGGGGTAACCCTCAAGCCGCTGTGGTGCAGAGGGTTATGCGTGTTTCACA ATTAAGCCGCGACA 41888 ADXCRPDRC.2412.C1_at GATGTCTGGCCCGCTGGGTCAAGAAGCCAACAAGTCATGTTGGCTCGGCAGAATGCATCCCT SEQ ID GGC NO: 1943 41888 ADXCRPDRC.2412.C1_x_at AGGGTCCTGTTTGTGCTTCCTGTAGACACCCTTTTCCTGCGCAACAGAGCTGGGCCTCCCTT SEQ ID TCTCTAATTTCCCCCTTAACATGCCTGGGGGGCATACAATCCAACCCGTGCCCTCTCCTCTC NO: TTCCTGCCAAGGTTTATAGAAACCTGAGAATCTGAGGGTGATGTCTGGCCCGCTGGGTCAAG 1944 AAGCCAACAAGTCATGTTGGCTCGGCAGAATGCATCCCTGGCATTCCCAGGT ARHGAP15 ADXCRPDRC.9769.C1_s_at TACCCTTCTGCGAGCTGAAAATGAAACAGGAAACATGGCGATCCACATGGTCTACCAGAACC SEQ ID AGATAGCTGAGCTCATGCTGAGTGAGTACAGTAAGATCTTCGGCTCAGAGGAAGACTGACAG NO: ACAAGACAAGCTACTGAATACGTTCACATCTGTCTTGATGCCTAATATTTTTACATTTCTGT 1952 AAACATATTTCTGAAATATTTTTTGCCTTTCAAGCGACAGATGCCTCATTTTGTGAA ALDH5A1 ADXCRPDRC.1911.C1_at GAAAGCAATGGTGAGCAATCTGGTTTACTGGTAACTTCAATATGAACTGTGAATGTGCCACA SEQ ID TGACTTTTTCCTCTAAAACTGGAATCCTAGGGTTTTAATTTACTGGNGTGCAGCTATTTTAA NO: ATAGCATTTACTTGGAGAAAAAAAGGNAGGTTGGGCATTGTTTCATGGCTAAACTTT 1957 ALDH5A1 ADXCRPDRC.1911.C1_x_at GAGCTGATCTGCATCTGTTTATCCATTTTAGTAGCTTTTAAATATGATTTTATGTGAAGTGC SEQ ID CATTTTTCTTATCTACTAAAGAGAGACAGCAGAAATAAAGATCNGAAAGCAATGGTGAGCAA NO: TCTGGTTTACTGGTAACTTCAATATGAACTGTGAATGTGCCACATGACTTTTTCCTCTAAAA 1958 CTGGAATCCTAGGGTTTTAATTTACTGGNGTGCAGCTATTTTAAATAGCATTTACTTGGAGA AAAAAAGGNAGGTTGGGCATTGTTTCATGGCTAAACTTT IGJ ADXCRPDRC.2619.C1_at ACAGAGACCTGCTACACTTATGACAGAAACAAGTGCTACACAGCTGTGGTCCCACTCGTATA SEQ ID TGGTGGTGAGACCAAAATGGTGGAAACAGCCTTAACCCCAGATGCCTGCTATCCTGACTAAT NO: TTAAGTCATTGCTGACTGCATAGCTCTTTTTCTTGAGAGGCTCTCCATTTTGATTCAGAAAG 1962 TTAGCATATTTGTTACCAATGAATTTNGAACCAGGGCNNNNNNNNNNNNNNGGGGGATGTAA AACAACTCCCTGCCACCAAAATAATTA IGJ ADXCRPDRC.4305.C1_at ATATTTGGACATAACAGACTTGGAAGCAGATGATACAGACTTCTTTTTTTCATAATCAGGTT SEQ ID AGTGTAAGAAATTGCCATTTGAAACAATCCATTTTGTAACTGAACCTTATGAAATATATGTA NO: TTTCATGGTACGTATTCTCTAGCACAGTCTGAGCAA 1974 NUP210 ADXCRPDRC.12713.C1_s_at ATTGTTGCTGTAAAGGTATCCCCTGTTTCCTACCTGAGGGTTTCCATGAGCCCTGTACTGCA SEQ ID CACCCAGAACAAGGAGGCCCTGGTGGCCGTGCCTTTGGGAATGACCGTGACCTTCACTGTCC NO: ACTTCCACGACAACTCTGGAGATGTCTTCCATGCTCACAGTTCGGTCCTCAACTTTGCCACT 1976 AACAGAGACGACTTTGTGCAGATCGGGAAGGGCCCCACCAACAACACCTGTGTTGTCCGCAC AGTCAGCGTGGGCCTGACACTGCTCCGTGTGTG ALDH5A1 ADXCRPDRC.14052.C1_s_at AAAGCCACTGAAGGAGGCACATGGAGAAATTCTCTATTCCGCCTTTTTCCTAGAGTGGTTCT SEQ ID CTGAGGAAGCCCGCCGTGTTTACGGAGACATTATCTACACCCCGGCAAAGGACAGGCGGGCC NO: CTGGTCCTCAAGCAGCCCATAGGCGTGGGCTGCAGTCATCACCCCGTGGAATTTCCCCAGTG 1978 CCATGATCACCCGGAAGGTGGGGGCCGCCCTGGCAGCCGGCTGTACTGTCGTGGTGAAG LBR ADXCRPDRC.5090.C1_s_at TTTTTGTAATATATGGTGACTTCAGATTTTTTTGTACAGTATTTTGAATGTGAGATGATTGT SEQ ID CAGGACTAACTGTCTTTTTAACAAAACATTTTCAGTATTTTAAATAAAATTTTGTAAAGTAA NO: TGTGAATTAAAAATTTTGGAACAATTAGAATTCATTCACTATTGTATAGAAGATGCTGTTAA 1982 AACATAGGAAGGGTATTTTTCTTGATCCAAAGTTTGTGAATTTGGCTTTGCTACCTCAATTG CAGGTGTTTGTT ATP2A3 ADXCRPDRC.4511.C1_at TCCTGAGCTCGGGAGATGTTCAGAGTCACACTGCCGCCCGGTCTGCCACGCAGAGGTCCAAC SEQ ID TTGCCACCCGCGTCCCTGGTACCTGAGACCACCGACATCCTCAGGTTCCTGACCGTGGCGCC NO: CTTCTACCCAGCC 1988 ATP2A3 ADXCRPDRC.4511.C1_s_at GTCAGAGAGACGGACACAAGGAGCCGGCAGGAGGGCGGAGCGAGGATGTCCTTTCCCGGGAG SEQ ID ACAAGTCGGGAAAGCCTGGCTGGACTGCCTCAGCCCCGCGCGCCTCCTGGACTCAGGGTTCC NO: CCGTCCTGAGCTCGGGAGATGTTCAGAGTCACACTGCCGCCCGGTCTGCCACGCAGAGGTCC 1989 AACTTGCCACCCGCGTCCCTGGTACCTGAGACCACCGACATCCTCAGGTTCCT ATP2A3 ADXCRPDRC.4511.C1_x_at AGGATGTCCTTTCCCGGGAGACAAGTCGGGAAAGCCTGGCTGGACTGCCTCAGCCCCGCGCG SEQ ID CCTCCTGGACTCAGGGTTCCCCGTCCTGAGCTCGGGAGATGTTCAGAGTCACACTGCCGCCC NO: GGTCTGCCACGCAGAGGTCCAACTTGCCACCCGCGTCCCTGGTACCTGAGACCACCGACATC 1990 CTCAGGTTCCTGACCGTGGCGCCCTTCTA LBR ADXCRPDRC.12940.C1_at CCATCCGGGCAAAGGACTTGGAGTTTGGAGGAGTACCTGGTGTGTTTCTCATCATGTTTGGC SEQ ID CTGCCTGTGTTCCTCTTCCTGTTGCTGTTGATGTGTAAACAGAAAGATCCCAGTCTTCTGAA NO: TTTCCCTCCTCCTTTGCCAGCTTTGTATGAGTTATGGGAAACCAGAGTATTTGGGGTCTACC 1996 TCCTGTGGTTTCTGATTCAAGTCCTGTTCTACCTACTGCCAATTTGGAAAGGTTGTAGAGAC GCCTCTTACTGATGGGAGCAGA EZH2 ADXCRPDRC.13819.C1_s_at AAGATGAAACTTCGAGCTCCTCTGAAGCAAATTCTCGGTGTCAAACACCAATAAAGATGAAG SEQ ID CCAAATATTGAACCTCCTGAGAATGTGGAGTGGAGTGGTGCTGAAGCCTCAATGTTTAGAGT NO: CCTCATTGGCACTTACTATGACAATTTCTGTGCCATTGCTAGGTTAATTGGGACCAAAACAT 2004 GTAGACAGGTGTATGAGTTTAGAGTCAAANGAATCTAGCATCATAGCTCCAGCTCCCGCTGA GGATGTGGATAC TPT1 ADXCRPDRC.14624.C1_at TTATGGGACGAAGAATTGGAACACATGGAAACCCTGTGCAGACTCCCGCGACATCTTCCCTC SEQ ID CTCTCCAAGTCCCTTCCCACAGACCTTGCGCCCCACACGATTATTCCCCAGGGGCCGAGCAG NO: GACGACTTGGGTCCCACTATCCGGACTCAGCGGTGCCCCCACAAAAGCGTCCCAAAAACTCC 2009 AGCTGGGGCAGCCCTGGGGCCGATGCTGAAAAGTTGTCAGAGGCCCTCGGGCAGTCCCGAGA TCTACCCCAGGCCAGAGGGCCTGACCCTCCCTAAATGCGACGTTCT ATP2A3 ADXCRPDRC.5908.C1_at ACAACGTGTCGTGCGCGCACCGAAGCCTTACGACCCCGACGGGCGGTGGGGACACCTATCAG SEQ ID GAAACAAAAAACGGCGGCACCGCTGCTAGGCCCCGCAAGGAGAGAAACAACACGAACAGCGA NO: GTGATGCCCCACTAAATGGCTCGCTTTTAATGACGGAACAAGCCGTCTGCGCCCCAGAACCG 2015 CGAGTGCTCACCGGAATAGAATCCGCACCAGCGCTAGGT CHD7 ADXCRPDRC.14939.C1_s_at TCCAATGAATCAGTCCGTACCAAGATACCCCAATGCTGTAGGATTCCCATCAAACAGTGGTC SEQ ID AAGGACTAATGCACCAGCAGCCCATCCACCCCAGTGGCTCACTTAACCAAATGAACACACAA NO: ACTATGCATCCTTCACAGCCTCAGGGAACTTATGCCTCTCCACCTCCCATGTCACCCATGAA 2016 AGCAATGAGTAATCCAGCAGGCACTCCTC USP7 ADXCRPDRC.16454.C1_at GGGATTTCCAATATTATGGGCATGGAGTAAATGGC SEQ ID NO: 2022 USP7 ADXCRPDRC.16454.C1_s_at GACTGAGTGAGTCGGTCCTTAGCCCTCCGTGTTTTGTGCGAAATCTGCCATGGAAGATTATG SEQ ID GTGATGCCACGCTTTTATCCAGACAGACCACACCAAAAAAGCGTAGGGATTCTTTCTCCAGT NO: GCAATGCTGAATCTGATTCCACGTCATGGTCTTGCGAATGCACAAGCAGTGCTGAAGATAAT 2023 AACTTACAGAGATGATGAAAAGTCGTTCAGTCGTCGTATTAGTCATTTGTTCTTCCA NUP210 ADXCRPDRC.15803.C1_at GTGGGGTTGTAAGTGATCGTGGGAGTAAGGTCCGAG SEQ ID NO: 2024 NUP210 ADXCRPDRC.15803.C1_s_at AGCATCTTGACATTTCCGTGGCAACCAAAGACGGGCGCCTATCAGTACACAATAAGGGCCCA SEQ ID CGGTGGCAGTGGGAACTTCAGCTGGTCTTCGTCAAGCCACCTGGTTGCCACAGTTACTGTCA NO: AGGGCGTGATGACCACAGGCAGTGACATCGGGTTCAGTGTGATCCGGGCACATGATGTGCAG 2025 AACCCACTCCATTTCGGTGAGATGA NUP210 ADXCRPDRC.15917.C1_s_at TCTGTTGCCTTGGTAACCCTGGGCTCCTCAAAGGAGATGCTGTTTGAAGGAGGTCCCAGACC SEQ ID TTGGATCCTCGAGCCGTCCTAATTCTTCCAGAACGTCGCCGCTGAGGACACTGACAGCATCG NO: GCCTGGCTCTCTTTGCCCCCCATTCCTCCCGGAATTATCAGCAACACTGGATCCTTGTGACC 2028 TGTCAGGCCTTGGGTGAGCAGGTCATCGCCCTGTCGGT PPRC1 ADXCRPDRC.16668.C1_at GAAGAGAGAAGTCCACAGCCCCCAACTGGGAAGTGGCCTAGCCTTCCAGAGACTCCCACAGG SEQ ID GCTGGCAGACATCCCTTGTCTTGTCATCCCACCAGCCCCAGCCAAGAAGACAGCTCTGCAGT NO: GAAGCCCTGAAACACCCCTTGAGATTTGCCTTGTGCCTATAGGTCCCAGCCCTGCTTCTCCT 2033 AGTCCTGAGCCACCTGTAAGCAAACCTGTGCCTCATCTCCCACTGAGCAGGTGCCATCCCAG AAGATGCCACTGTTGGCGAGACCTT ALDH5A1 ADXCRPDRC.1124.C1_s_at GTGTTTTAATTACCTGTGTGCAGCTATTTTAAATAGCATTTTACTTGAATAATATGTATGTT SEQ ID GTCATTGTTTCATGCTATACTTTGTGGGATAAAACTTGGGAATGAGTGTGGTAAGAAATTTA NO: TAAAGTTTTGCTTTTAAAACGTGGACATAACTCAT 2038 ALDH5A1 ADXCRPDRC.1124.C1_x_at TCCTCTAAAAACTGGATCCTAGGTGTTTTAATTACCTGTGTGCAGCTATTTTAAATAGCATT SEQ ID TTACTTGAATAATATGTATGTTGTCATTGTTTCATGCTATACTTTGTGGGATAAAACTTGGG NO: AATGAGTGTGGTAAGAAATTTATAAAGTTTTGCTTTTAAAACGTGGACATAACTCATTTTTC 2039 TAGTTTTTGACAATTGTGTGTTTTAGTGTCTAGTCTGCAGAGAGCTGTGTGATTAATAAACG TGGAATTAACAGAATTTCCTCTCCCTGTAA MFNG ADXCRPDRC.7895.C1_s_at AACCCAAGGGCGCTGCTGCAGCTTCTGAGAGCCTTCCCGCTGGCCCGCGACGTCTATGTGGG SEQ ID AAGGCCCAGCCTGAACCGGCCCATCCATGCCTCAGAGCCACAGCCCCACAACCGCACGAGGC NO: TGGTACAGTTCTGGTTTGCCACTGGGGGTGCTGGCTTCTGCATCAATCGCAAACTGGCTTTG 2043 AAGATGGCTCCGTGGGCCAGTGGCTCCCGTTTCATGGACACATCTGCTCTCAT PIM2 ADXCRPDRC.11037.C1_s_at GGTCATTACCAGTCATTAAAGTCCAGTATTACTAAGGTAAGGGATTGAGGATCAGGGGTTAG SEQ ID AAGACATAAACCAAGTCTGCCCAGTTCCCTTCCCAATCCTACAAAGGAGCCTTCCTCCCAGA NO: ACCTGTGGTCCCTGATTCTGGAGGGGGAACTTCTTGCTTCTCATTTTGCTAAGGAAGTTTAT 2050 TTTGGTGAAGTTGTTCCCATTCTGAGCCCCGGGACTCTTATTCTGATGATGTG TRIM14 ADXCRPDRC.2569.C2_at GCAGCAGCAGACTTGTTTAGGGCCTGTTTGAAACTAGCCTAGGAGAGGAAACCTTCAAAGCA SEQ ID CGGTAGGCGTGATGGGTCGGGGAAAGCTGGGGCAGGGAGAGGGCCCTAAGAAGCAGGCAGTA NO: AGGGGACCAGCCACGCTGATCTAGGTAGATTAGGCGAGACTGGGCAGCTGCGGCGACCTGGA 2053 GGCTGTCACGCCGGTCCT AKAP1 ADXCRPDRC.3886.C3_at GTCTACATGATGTTGAGAGCCTTCTATGTGGCAGATCTGGACGCTCTGGGTGTAAGGCAGGG SEQ ID TTGAAATGTAGATCTTGGCACCAGATGTTTGCTTCAGAAAACTCACATAGCGCCCCTGCTTG NO: CCAATTAGCCGACCGACTAAGTGCTTTGGCACCTCGATCTCCCAGATGATGAGGTCGACCTT 2054 CTTAGGGTTGGAGCCTGCCTGGGCATTTTGGAAGCTCTCAGTCTTCTTGAGACTGCAACAGC TATCCACGGAATCCATGCTGTTCCTGTCAGAACCCTGT PDSS1 ADXCRPDRC.11127.C1_at GCACACCATCACTCTGTAGTACATACTGTCGAGCTCTGTCTACATCTCCAGGCAAACTGAAC SEQ ID CGTCGCATGATCATAGCATTCATTTCTGGGAACTGCTGACAGGCAAACAGGACAGGACCAGT NO: GGCTAACCCGAGCTTCAGATCAGCTGATGTTGGTTTGCCCATCTGGTCAGAACACGAGGTGA 2058 AGTCCAATACATCATCTATTAGCTGAAAAGCTATTCCTACATTTTTTCCGTACTGATAGGCG ATCCCA HNRNPA2B1 ADXCRSS.Hs#S1848110_s_at TCAAACGTGAATACAAATCCAGAGTAGATCTGCGCTCCTACCTACATTGCTTATGATGTACT SEQ ID TAAGTACGTGTCCTAACCATGTGAGTCTAGAAAGACTTTACTGGGGATCCTGGTACCTAAAA NO: CAGCTTCACATGGCTTAAAATAGGGGACCAATGTCTTTTCCAATCTAAGTCCCATTTATAAT 2066 AAAGTCCATGTTCCATTTTTAAAGGACAATCCTTTCGGTTTAAAACCAGGCACGATTACCCA AACAACTCACA CYFIP2 ADXCRSS.Hs#S2524484_at GGCTCAGTGCGCACAACTAGCTAGAGGCACTGACTTTGTAAGCAACAACACTATCTTCTTGA SEQ ID GGTCTAATAATTGCCTTGGCAAAGGGCAGCCAATGCCAACGAGGAACCCTGTGTACACAAGT NO: TTCTCATCCCGAAAGTGGACACTGGGTGCTCAAAAAATGCCTTCTGGTGACAGTAACACCTG 2071 ACCAGTCAAACAAACATGCACGCA IQGAP2 ADXCRSS.Hs#S1611967_at GCTTTAGTCCTGAATCTAATCACATGGAAATATATTCTTGATCCATGACTGTATTGTCAACA SEQ ID TATCCCCATTTGCATAGTATGATCCACTTGAGAGCTGAGTTGTCGGCAATATTTTTAAAATC NO: GCCCTGAATCATGTGTTAATTCACACTCACTAACAGCATATGCTTGCATTAATAGCACCCGT 2080 CTGTTCAACATCATAATCTTCTAATGGTGTCTGTAATATAAAACTTCTCTTCCAAATATAAG TTTCGACTTAAAGTCAGCTCCTTAGTATATCCCTTACCGATGGAAAGAC CHD7 ADXCRSS.Hs#S1919211_at GAATCAACTCTATATAATCAACAAGAGAATTAGGCAAATAACATCTGGTTGCACTGATGGAC SEQ ID AAAGGACATAAAGATGTTATTTTCAAATGTCTTCTCCTGAAGAAAAATGAAAATTGTGTAGC NO: CAGTCACCATTTTAGGCCACTCATTCTTGTCCAGTCATCTGTAGGATTATGGTTTGAGGGAC 2093 T SKAP1 ADXCRSS.Hs#S1928672_at ATATACCCAATGTCAAATCACTTTTTATGTATACACCAAAAAGGCACTCAATATTAGGACCT SEQ ID ATCCCATATCCAGGCACACAGTAGGGAACCGTACTCCAAAGTGACTATCTGCTAGGCCAGAA NO: AAGACCAAGATAACCTTGTTAGTCTCCTTACCACTTAGAAATATTGTTATGGTTTTAGAATC 2116 TATTTTTACAAAAATGGTTTTCTCTACCATATATAAATCCATGAAAAATATTGATGTTAATA TTCTTTCATTCCTGAGTTTAGTCAA IQGAP2 ADXCRSS.Hs#S1928867_at GTGTATACAAAGCTCTTAGCACAGAGTGAAGCTCAGTGAACAAATGGCTCTTCTTATGAAGA SEQ ID GCAGCCCTCAGCGGAGGCATGGCACCTCCTTCAAGAGAACCAAACTTGGAAACCTTGAATTA NO: GGAAGTGATTACTCACTTTACAGGGAATGACTACGGTAATGATATATTTGCTTTCTGTTACC 2118 TAAACTTAGCAGCTTACATATTTATCATCTAATGGTTTCTTTAGCTCAGAAATGTGGGCATA GCTTTATGGGTCCTCTACTT BCL11A ADXCRSS.Hs#S2731126_at TGCAGTAACTGTGCGCCTATTGTAAAGGCAAATGAAGCTCACCTATTCCCTGCTGGGATCAG SEQ ID AAGTGACCTCACCACCCCCCATGCCTCAAATCCTTCCCTTGCCAACCTAACTCAATGCCATT NO: GCAGAATGACGAATGAGCTCAGAAATAGACCCCAAGTTACTAACCCTGCTAAGAACAGCAAA 2139 AGCCTTTGCTGAAATGTTTTAAAAATGCATAGGGAGTGCAGCTGGCCAGTAAAAAGCAGGGA GACAAATTCCAATGAACCCAA TOP1 ADXCRSS.Hs#S2990754_at AATGTTTTGTGCTTGGATTGAGTTTAGAGACACCAGATAGAATAAGATTGGCAACACTGTTA SEQ ID GCCACCTGCTGACCACAGCTAAACAGGCATATGTGCTTCTGCATGGGGAATGCTATGGCGTT NO: AACAGAGCCTTCCTTAAAACCTGTAAGTTCGTTAGGCTTCCGGGTACCAGGGTTGTTAGAGT 2140 AGGCCACAGTTTACTTCCTTTTTCATAAGTGCTTTTCTTTCCTGGATCTCAGTATAGGAAGG AAAATCAGACAGCATTTCTCAATTGTTGACGCGTAAGGGCCA USP7 ADXCRSS.Hs#S2990382_at GATAAATCTTCGTGAAGTGGCAGAAAATATGAAAGCCAGCCAATTGGAATCTTGCTTATTCT SEQ ID GATCTGTTATCTCAGGGGTTAGATTCGCGTGCTGAAGTGGTCTACGTAACTTCCATAGCGAT NO: TGGGAGGTGTTCTCTGGTGGGGTAGCAGTTCTGTGTTATGACATCACACATGGAATTCACGG 2141 GGAGGAAAGCTGGGTATAGGCATTAAGTGCCCAGTAGAGCAGGT TPT1 ADXCRSS.Hs#S2979085_at GGGTGCAGCACAAGTTCCTTCATAGGACTTTAAGACTCTTTGGGATCTAGTCCCTGCGTATC SEQ ID TCTCCAGTTCTCCTTACCATTCTCCTGTATCTGCCTCTGGCTGCAGCTGTGCCACAGCCAGA NO: CTCTGGAAGGAGCCTCTTGCTGTCAATTATCCAACAAGTGTTTACTGGGTACCCACTTCTGC 2143 CAGGCACTGGGTTAGAGGTTGGAGACATAGCAGTAAAGACTTGCTCTAGTGGAAGACAA CYFIP2 ADXCRSS.Hs#S3733207_at GCCTATGTTGTAGAATCCCTCGTACCCAGAGTGGGAGAAGATTACACCCGGGGCACTGCAGG SEQ ID GAGGGAACCAGGAGAGATGAAGTAGTAAGCTGAGGCATGCCCTTCTGGCCAGGCTGGCGTCT NO: CTGGGCATGGCCACATCTGTTCACAGTCTGAGACTTGAGTCCTGGGGTCACACAAGGGCACT 2161 GGGTAGGAGATGTCTATCTTGGGAGGAGGTCTTGGGAAGCAACCACAGATAG NFATC3 ADXCRSS.Hs#S3740808_s_at AAAAAGCAATTTCAACATGGAGCCAGTATGGAGAGATTGCAAGATTACCTAGAAAGTTACCA SEQ ID AAAGGCTATGCTCTGGAATGTCTTTTTATATTCCAACACTTCAATGATGGAATGGTCTCTTC NO: TCATTTTATCTAACAACAGTTTAGTTTTATAAAGAGGTATGAGCTACATTTGGCTTTATTTC 2162 CTATAAATCTATGAACGTCTTCAGGACACATGCTGACTTTCTGAGGCA CALML4 ADXCRSS.Hs#S2988186_at ACGTCTTTCCCGCTCACTGTAGCTGCCACCCATTCTTTTTAATCCCCAGAGAGCATACAGAT SEQ ID GAGCCCCAGTGGGCCATCTCAGCCACATAGGGGACAGGCCGGGGAGAGGATCTAGAGCTGGC NO: CCAGGAAAGGAGGCCCTTTTCATTTTGAGGGAGGCCTCCCATCAGAGAAGGGTCCAGTCCTG 2163 CCCCGACCCTGTCCTTCCCATGATACCCACAATCCCAGGGTGACCTGTCTCCAGGGCAGAAG TGACAGACGAGGGCTAGGAGACTGGCTGAGGCCTAAGTCCTCTGCAAT SKAP1 ADXCRSS.Hs#S2988136_at GAGAGAAGTGGGAAGCACTAGACACTTATCAAAC SEQ ID NO: 2165 SKAP1 ADXCRSS.Hs#S2988136_x_at GAGAAGTGGGAAGCACTAGACACTTATCAAACAACCAGATCTTGTGAGAACCCACTCACTAT SEQ ID CATGAGAGCAGCAAGGGGCAAATCTGCTCCCACGATCTAATCA NO: 2166 SKAP1 ADXCRSS.Hs#S3015915_at TCTACCTCAGACATTCCCATTCTAAATATGGTGGGCCTGACACTGCAAAACTGCTAAAGAAG SEQ ID TTCCACACAAAAATGTGTTTTAGCTTTAATTACTTATTCAGTTTAAACAAAAAAGAATTTTT NO: TTAAATTACCAGCTCTTTTGTTTTCAGTTCTCATAAATACATCTGGTTTCCCCCTCTCTCTC 2172 TATCTGATAAAAGTATTCTGAAAGGCAGAGTCCGGAGTGCCGAGGTTAGAGGATCTAGAA SKAP1 ADXCRSS.Hs#S3015915_x_at CTAAGAATCCTTCTACCTCAGACATTCCCATTCTAAATATGGTGGGCCTGACACTGCAAAAC SEQ ID TGCTAAAGAAGTTCCACACAAAAATGTGTTTTAGCTTTAATTACTTATTCAGTTTAAACAAA NO: AAAGAATTTTTTTAAATTACCAGCTCTTTTGTTTTCAGTTCTCATAAATACATCTGGTTTCC 2173 CCCTCTCTCTCTATCTGATAAAAGTATTCTGAAAGGCAGAGTCCGGAGTGCCGAGGTTAGAG GATCTAGAA TPT1 ADXCRSS.Hs#S3017795_at ACTACTCCAGATTTTTCACCTGCAAGTGGTAAGTCAGGCCAACTTCCGTTGGTGACCCGTTA SEQ ID TCTCTGCTTGAAAAAAGATAAGGAGATTCTCCACTTTGGCCTCAGCTCTTAGCTAGGTTCTT NO: TAGTCCAGCTAGGAGTTACTGAGCCTCCACCAAGAAGGTGAATCATTTGACCTCATTTAGCT 2175 CCTCCTCCTTATTTATCTTTATTAGAGCTTGCAGTGATGGAGAGTAAGTGATTGGGACCTCA AACTTCTAACACATAATTCTCTCAGGCGGGTTTGGAATGGTACTCTA BLM ADXCRSS.Hs#S3004537_at GCTTACAACAGTCCATTCATCACCACTTCTTGTTCAGCTAGTTACATATCTGTCTTCAGACC SEQ ID ATGTTTCTGTTCTTTATCCATGGAGACACAAAAGACTTGACTATGTGACTCCAATAAGTTAG NO: AGGTGTGAGGCAGCAAGAATGATTGGGTGGGACATTGACTCTAGAGTCCTACAGACCTGTAA 2178 TATAAACCTGTCTCCTCCTACTCTTTACTATGTGACTATAGCAAATAGTTTAACTTCTCTGG ACTTCAGTTTTTTCTTCTATAAAATGAGGAGAATGATATCTACCTTGC PCBP2 ADXCRSS.Hs#S3736726_at ATCCCTAATAGGCTGGGCTTTGCAGGAAATGGCATGAAATCAGCTCTTCTGAGTGTACAGAA SEQ ID GAACCTTTCGAGCATTATTTCTACACCCTTCTCCCCCACTCTTTCCTCTTTGGAGGCTTCCA NO: AGTTAGTGATGAATCCCAACAGCTAATGATGCTGGGTTTCCAGTTTATTTCCTTCTGTTAGT 2209 TTAATGTGCAAGTCAGTGAGGTTTTGAATGCTGTGCATTGAATTTGCTTGCTCTCTTCTGTC TTTTAGCAGGTTT IMPDH2 ADXCRSS.Hs#S3737705_x_at GATCTTCACTTTCCGAACTTCATTGGCCTGGAATTCAGGTAGTACAGTATGTGGTGGATGAA SEQ ID GCCAACTACCGCCTGTAAGCTACAGGATAGAAAAGAGACTACTACTAAGTGACAAGAAGCAG NO: GACTGAATGCCTTTGGGGGAAAGGCGGATGGAGTCCTTGCTCCTTTTCCCCAAACCCCATGG 2216 GGCTCACCGCCATTGCTATGGCCATCCCAGGCTTCTGTTGACTGTGTCCATTGGGAGAAGGA AAACCAGTGGGGTCTTAAGAAGTGATTTTCTTGGTCAGAGCAG MYC ADXCRSS.Hs#S854806_at GGGAGGAGACTCAGCCGGGCAGCCGAGCACTCTAGCTCTAGGATGTAAACAGAGTAAGAGAG SEQ ID CCGCATGAATTAACTACGCGCGCCTACCATTTTCTTTTGCTCCCTCTCAAACCCTCTCCCTT NO: TCTCTGCTGCTCCTCCGTAGCAGTACTGTTTGACAAACCGCATCCTTGTCCTGTGAGTATAA 2226 ATCATCGCAGGCGGAACAGCTG IFITM1 ADXCRIH.37.C1_s_at GGGTTACTAGTAGCCGCCCATAGCCTGCAACCTTTGCACTCCACTGTGCAATGCTGGCCCTG SEQ ID CACGCTGGGGCTGTTGCCCCTGCCCCCTTGGTCCTGCCCCTAGATACAGCAGTTTATACCCA NO: CACACCTGTCTACAGTGTCATTCAATA 2227 RPL10A ADXCRIH.799.C2_at GTTGAGTTTTTTCAGCGCCTCGATGTCCATGTGGGGGATATCCACGGCCTTAGCCTCGTCAC SEQ ID AGTGCTGCTGGTCCCCCAGGACACACACAGAGAACTTAGGGCGGGGAGTGGACTTAAGCCTG NO: ACGGTGCCCGAGAAGCGCTTGTCCTTCTGGGGATCATAGTTCTTCAAGCTGATCTGCAACTC 2230 CACCGTCTCCAGGAACTTGCGGCGCTTGCGCTGGTTCCCGTGCAGGACTTCCCGCACCGCCT CGTACAGGGTGTCGCGAGAGACTTTGCTGCTCATGGCTTCTCA GTF3A ADXCRIH.2186.C1_at CCCAGGGCCAGGCGCGCTGCCACGTGCCCCTGCA SEQ ID NO: 2252 GTF3A ADXCRIH.2186.C1_s_at TTTTTGATCACAGCCATTGGCTGCACAAACAAACGGCTTTTCTCCTGTGTGCTTGCACAGGT SEQ ID GCGCGTCAAGCTTCCAGGCTTTGCTGTAATTGGCGCTGCAGTCAGGGAAGGAGCAGATGAAC NO: CTCCTGGGAAGCGCGGGGCGCGGCGGGGTCGGAGCTGAGCTCTCGCCGGCTGCAATGAACGC 2253 GTCGGCGATGGTCAAGGACGACACCGACTCGG GTF3A ADXCRIH.2186.C2_at CAAGAGAAAGCTGTGGAAGACCTATACAACTGTGGTTTATCTCCAAAGCCATATCCCTCTTC SEQ ID TTCCATGAGGAAAGGCCGCCC NO: 2254 GTF3A ADXCRIH.2186.C2_s_at TGGCAAAAACATGGACGGAACTTCTGAAACATGTGAGAGAAACCCATAAAGAGGAAATACTA SEQ ID TGTGAAGTATGCCGGAAAACATTTTAAACGCAAAGATTACCTTAAGCAACACATGAAAACTC NO: ATGCCCCAGAAAGGGATGTATGTCGCTGTCCAA 2255 ATP5G2 ADXCRIH.3160.C2_s_at TCCCATAGTTCTCCCGCGTCTGGTTGGCCCCGTGTGTTCCTTTTCCTATACCTCCCCAGGCA SEQ ID GCCTGGGGAACGTGGTTGGCTCAGGGTTTGACAGAGAAAAGAC NO: 2262 RAD51C ADXCRPD.305.C1_at GTTCCTGCATTAGCCTCAGGGATTTAGAGATACTGTTGTTACTTCTGCATGTTCATTGCAAA SEQ ID CAGAAGGTTCCTTGAGCACCCGGAAACGGTCACGAGACCCAGAGGAAGAATTATAACCCAGA NO: AACAATCTCAAGTGTACAAATTTATTGATGTTGTGAAATCTATGTGTACAGTGGACTTGTTA 2263 CCTTAAAGTATAAATAAACACATCTATGGCCATGAATG RAD51C ADXCRPD.305.C1_s_at CAGGCCTTGCTTGTTCCTGCATTAGCCTCAGGGATTTAGAGATACTGTTGTTACTTCTGCAT SEQ ID GTTCATTGCAAACAGAAGGTTCCTTGAGCACCCGGAAACGGTCACGAGACCCAGAGGAAGA NO: 2264 RAD51C ADXCRPD.305.C2_x_at CTCTTAATTTTAAGTGTGTATGTGCATTAAACAAAAATTAGCTTACTANNNNNNNNNNNNNN SEQ ID NNNNNNNNNNNNNNNNNNNNNNNNNNNNNACTCCACGAAACCACAATCCCAACCNAATCACA NO: AAAACAAATTTTGGGCCCCTTCGGCCCCTCAGAAAACTTTCTAAAACCCTTTCGTTTGGGGG 2265 CGGGGCGCCCCCATAAGGTATAATGGGACCCTGGGCCCTAAGCGTGGNTTCCCTAGGAAAAA ACCCTGGGCCACCTGAACCAAATGGGCGCTGGG PRIM1 ADXCRPD.724.C1_at CCGTGAATTGGATGCCATTTCCACTAATGAAGAGGAAAAAGAGGAGAATGAAGCTGAATCTG SEQ ID ATGTCAAACATAGAACCAGAGATTATAAGAAGACCAGTCTAGCACCTTATGTGAAAGTTTTT NO: GAACATTTTCTTGAAAATCTGGATAAATCCCGAAAAGGAGAACTTCTTAAGAAGAGTGATTT 2266 ACAAAAAGATTTCTGAAGACAGAGCTCCTCAAACCATTGTGGATATCTTCTGCCTTCAACCA CAGATCAAATACTTCAAGAGCCATTTAATAAA PRIM1 ADXCRPD.724.C2_at GCCATTGCAACTGGCCGTATTAAGTCCTTTGTATCCTCACTGTTCCATACTAGCTCAGCCTA SEQ ID TGATGTGGACTTCAGCAAATGTGTAAGCAAATCTTTGTGCATGATGTGTGTTAAATAGAAGC NO: ATTAGGCAAAAAAGAATGTAAAAGTAAATGGGCTTTGTTTTGTTTCCTTTGCTGTTCTTCCA 2267 TATATTATC TRIM14 ADXCRPD.2569.C1_s_at CATTCCCAAGGGAGCTTGCACGGTACTGACCGAGTGCTGAGACTACTGGTATTCCCAGCTGC SEQ ID CATGTGGCAGCAGCAGGAGCTACTAGAATATTCTCAGCACAGGAATGAGGCTTCCTTGGTTT NO: CCATGTCTGTAAGGGTTACTGATCACTTACCTTCTTCTCTT 2276 AKAP1 ADXCRPD.3886.C2_at TCTGCTGGTCGGTTCTGCTATGGGACTGTGTTCTGGGGACAGGGCTTAGGTGGTGATAGCGC SEQ ID TGGCAGGAAACCAGAGGCCTCTTGGTCCCCACATGGGAGGACTACTTTTCCTGGCTCTGCCC NO: CCTGGGCACCTTTTAAGTTTTCTAGGCGTTAGCTTAGAAAGGATGGTGTAGTTAGGACAGGA 2279 GATTGGGTGTGTCCAGAGTAGACGTTCACCACCTGAGACCTGGGTGGGACTAGAATCATGGG TTTGGATGGCGCTTGTTCTTTCTTCTGGTTGAGTCAGGCCTTAACA DAZAP1 ADXCRPD.4725.C1_s_at GGCTTTGGACGAGGGCAGAACCACAACGTGCAAGGGTTCCACCCCTACCGACGCTAGCCCGC SEQ ID GGCGCCGCGAAGTCTTGCACGGCCCAGACCCAGGATTCCAAACTTGTGAACTCGTGACAATC NO: ACAAACTTGGCGGCAAAGTGGCGACTCAACCTTNNNNNNNNNNNNNNNNNNNAGGGCGCGAG 2280 GCTTTTGGAGCGGCTGTGGGTGTCGTCTGGACTGAGGTTTTTAAATATTTCTTTCTCTAACC CATCAGCACAATAAA DAZAP1 ADXCRPD.4725.C2_s_at AAATCTACTGAGTGTATTTCTGTTTTTTGTTTAATTCCTTGCTTTTGTCGACTGACCTGCTT SEQ ID GGTAGTGTCTGAGGTGAACTGTGGGGGTTGCGCACAGCCAGCCGCGTGGATCCCACGCAGCG NO: CTGAACCGAACCGAGTAGGAA 2281 IRF7 ADXCRPD.7919.C1_at TGGCCAGGTGTCACAGGTGTCCACAGGTGTGGACTGAGGGCTTGTAGCCACCGACGCTGCCT SEQ ID CGGTATGGATCTCTTGGCAGAGGGGGCTACAGGTGTGACTGCAGGTGTGGCCGGCGCGCACA NO: CATGAAGTCACAGGTGTTGAACCAGTGTCCAGGCCTGGCGGGAAGGCGCAGGCCGGATCACT 2289 GGGTGCCAGAGCCGCCGGGACGGGAAGTTTCGTCTCGCGGGGAAGTCAGGAGGGCCGGCGCT TTCACTCGTGCCGAATTAAACACCCGG IRF7 ADXCRPD.7919.C2_at CTGCCGCGGCCGCCCAGTCTAATAAAAAGAACTCCAGA SEQ ID NO: 2290 IRF7 ADXCRPD.7919.C2_s_at AGAAGAGCCTGGTCCTGGTGAAGCTGGAACCCTGGCTGTGCCGAGTGCACCTAGAGGGCACG SEQ ID CAGCGTGAGGGTGTGTCTTCCCTGGATAGCAGCAGCCTCAGCCTCTGCCTGTCCAGCGCCAA NO: CAGCCTCTATGACGACATCGAGTGCTTCCTTATGGAGCTGGAGCAGCCCGCCTAGAACCCAG 2291 TCTAATG FBXL14 ADXCRPD.10538.C2_at AATCTCATTGGATTACTCCTCCTTACATTACTGCGTTTGGATTTGTAGTCTTAACAAGGCAA SEQ ID TAAATGGAAGGGGAAAGAAGGAATCAATTCATGGTAACTAGAATGTAATGAGCACTTGCATT NO: AAGTCACAATTTAATTTGTATACTTTCGGAAATTCTTTCCTGGTTGTAAGCCTAAAGGGGCC 2297 TGCCTAG LGALS9 ADXCRPD.14181.C1_at GCACAGTCCCTGTTCAGCCTGCCTTCTCCACGGTGCCGTTCTCCCAGCCTGTCTGTTTCCCA SEQ ID CCCAGGCCCAGGGGGCGCAGACAAAAACCTCCCGGCGTGTGGCCTGCCAACCCGGCTCCCAT NO: TACCCAGACAGTCATCCACACAGTGCAGAGCGCCCTGGACAGATGTTCTCTACTCCCGCAAT 2307 CCAGCTATGATGTACCCACAACCAGACATCCGAAGCGTAACATCAACCACCAG LGALS9 ADXCRPD.14181.C1_x_at AGCTGTCCTACATCAGCTTCCAGAACCCCCGCACAGTCCCTGTTCAGCCTGCCTTCTCCACG SEQ ID GTGCCGTTCTCCCAGCCTGTCTGTTTCCCACCCAGGCCCAGGGGGCGCAGACAAAAACCTCC NO: CGGCGTGTGGCCTGCCAACCCGGCTCCCATTACCCAGACAGTCATCCACACAGTGCAGAGCG 2308 CCCTGGACAGATGTTCTCTACTCCCGCAATCCAGCTATGATGTACCCACAACCAGACATCCG AAGCGTAACATCAACCACCAG LGALS9 ADXCRPD.14181.C2_at AAGTCCATCCTCCTGTCAGGCACTGTCCTGCCCAGTGCTCAGAGGTTCCACATCAACCTGTG SEQ ID CTCTGGGAACCACATCGCCTTCCCACTGAACCCCCGTTTTGATGAGAATGCTGTGGTCCGCA NO: ACACCCAGATCGACAACTACCTGGGGGTCTGAGGGAGCGAAGTCTGCCCCCAAAAATGCCCC 2309 TTCGTCCGTGGGCCAGAGCTTCTCAGTGTGGATCTTGTGTGAAGCTCAGTGCCTGACAGGAG GATGGACTTGGATGGGTACAGCCCCCCCAGAATGGTGGTGATAA CALML4 ADXCRAD_BQ928122_at CTGGCCTGCAGGAAAGGAGCGCCCAGCTGCGCGCCTGGGCCGCCCGTCGCTCCCAGTGCTGC SEQ ID CGCCCTCGCGTTGCCTCCATGGCTGCCCCGCAGGCCCCTCGGCCCTGCCTTTTCCGAGGAAA NO: AACGGTTCAGCTCGGTG 2341 CALML4 ADXCRAD_BQ928122_x_at AGGTCGAGGTGGAAGGGAGCCGTGCGGGCAGCCTCATCAGCGCTCACAGAGCCATGCCTGGC SEQ ID CTGCAGGAAAGGAGCGCCCAGCTGCGCGCCTGGGCCGCCCGTCGCTCCCAGTGCTGCCGCCC NO: TCGCGTTGCCTCCATGGCTGCCCCGCAGGCCCCTCGGCCCTGCCTTTTCCGAGGAAAAACGG 2342 TTCAGCTCGGTG ANP32A ADXCRAD_AL547157_s_at AAGAAGGTTATAACGATGGAGAGGTAGATGACGAGGAAGATGAAGAAGAGCTTGGTGAAGAA SEQ ID GAA NO: 2357 ANP32A ADXCRAD_AL547157_x_at GGAGGATGAAGAAGGTTATAACGATGGAGAGGTAGATGACGAGGAAGATGAAGAAGAGCTTG SEQ ID GTGAAGAAGAAAGGGGTCAGAAGCGAAAACGAGAACCTGAAGATGAGGGAGAAGATGATGAC NO: TAAGTGGATAACCTATTTTGAA 2358 BCL11B ADXCRAD_CD701737_s_at TTGCAGCATATTCTTCTCTTTGGCCCAGAGGTGGGTTAAACTGTAAGGGACAGCTGAGATTG SEQ ID AGTGTCAGTATTGCTAAGCGTGGCATTCACAATACTGGCACTATAAAGAACAAAATAAAATA NO: ATAATTTATAGGACAGTTTTTCTACTGCCATTCAATTTGATGTGAGTGCCTTGAAAACTGAT 2359 CTTCCTATTTGAGTCTCTTGAGAC USP7 ADXCRAD_BU956106_at CGCTCTTTCCCTTCATTGTGGGGCATTGTTCGGGCCCTTC SEQ ID NO: 2368 AKAP1 ADXCRAD_BX394525_at AACTCATTGAATTAACTTGCAGTGGTGTGTTTGATTCTTTTTTAGACTGGCTTCAGCATTGT SEQ ID GCAGTTTAA NO: 2377 NASP ADXCRAD_BQ187021_at CTGGGGCTATAATTCTGTCCTGGAAAAAGAACTCTGAAAACCTGGGTCAGGGGAATGATTCC SEQ ID TAAGGAAAACGGTCTGCATTTGAGCTCTGGTTTGAAAGTAGCCAAGGGGACTGATGGTGGAC NO: ACTCCAGATGTGGTTGGAAGCATATGTGGGGAGGCTGGCTGGCTGAGTTTTGTTATTTTCTG 2384 TATAGAAAGGTTGAGATATATCAACACTTGGGATTGTTACCCATCTGCAGAATTGACTTCTC AAATAAAGATGCTA MYC ADXCRAD_CA454569_at TAAATATTGGGCCATTAAATGGTAAATAAACTTTTAATAAAACCGTTTTATTAGCAAGTTAC SEQ ID ACCAGAAATTTCAATCCCCTAGGTATATATAGTACCCTCAAGTATTTATTA NO: 2390 HMGB1 ADXCRAD_CN401906_s_at AACTCATTCATTAGTCATGTTTATCTGCTTAGGAGTTTAGGGAACAATTTGGCAATTTTGTG SEQ ID GTTTTCGAGATTATCGTTTTCTTAAAGTGCCAGTATTTTAAAATAGCGTTCTTGTAATTTTA NO: CACGCTTTTGTGATGGAGTGCTGTTTTGTTATATAATTTAGACTTGGATTCTTTCCATTTGC 2402 ATTTGTTTATGTAATTTCAGGAGGAATACTGAACATCTGAGTCCTGGATGATACTAATAAA TRIM14 ADXCRAD_BX389413_at TGGTCTCACTGGGAGTTCATGGTGCTTCAGTCCCTAGCACCCAGTGATACCCCCACAGGTAG SEQ ID CCCTAAGCATCCTGAAACATCATCCGC NO: 2407 RNF44 ADXCRAD_CX761728_at TTTCTATTGTTGCTGATTCCGAGGGATATTCCCTATAATGTATGA SEQ ID NO: 2410 RNF44 ADXCRAD_CX761728_x_at AGTTACCTCATTTTTCCCATGTATGTATTTGAGAAAATGCTAATATATAGAGAAAAAAATGG SEQ ID TTCTTAAAGCTTAAATGTGTGGTTTTTTCCATTCCATGGGATTCACATTGGTTTGTAGCATT NO: TAACATAACTAGTATGTTGTATTATATATATGTGTATACTGATTGAAATTTTTAACAGATTT 2411 GTACTTTTTTTAAAATGAAAGTTGCTAGTTCTGCTTGACCAAGTAGTGGCATCATTATTTTT TTTTCTATTGTTGCTGATTCCGAGGGATATTCCCTATAATGTATGA ATP5D ADXCRAD_AL548640_at GAAGCCGCGCCTGCCAAGGAGGCCACCAGAGGGCAGTGCAGGCTTCTGCCTGGGCCCCAGGC SEQ ID CCTGCCTGTGTTGAAAGCTCTGGGGACTGGGCCAGGGAAGCTCCTCCTCAGCTTTGAGCTGT NO: GGCTGCCACCCATGGGGCTCTCCTTCCGCCTCTCAAGATCCCC 2419 PIM2 ADXCRAD_BQ953509_at AATGTAAATAATCACGTATTGTGGGGGAGGGGGAGTCCAAGTGTGCCCCTCCTCTCTTCTCC SEQ ID TGGCTGGATTATTTAAA NO: 2423 PIM2 ADXCRAD_BQ953509_x_at GGGAAATAAGGCTTGCTGTTTGTTCTCCTGGGGCGCTCCCTCCAACTTTTGCAGATTCTTGC SEQ ID AACCTCCTCCTGAGCCGGGATTGGCCAATTACTAAAATGTAAATAATCACGTATTGTGGGGG NO: AGGGGGAGTCCAAGTGTGCCCCTCCTCTCTTCTCCTGGCTGGATTATTTAAAA 2424 LRMP ADXCRAD_BG257134_at ATTGAACTTACGGACTCGTTAAGCTTGAAGACAAAACAGGGGGGGGCGCAAAGAACCCAGGA SEQ ID GGGCCAGCTACACAACCCGTTCTGGTAAAGGCGCACAAAGGGCGAAAAAAGAAGCGCGGGTA NO: ACACAGCAGGAAAAGCGGTATCCTAGGACAACTGGTGGATAGCACCCAAAGAGAGCAACATG 2430 TAGGAAGCCTGCGCACAGGTAGAACAGCAGCAAAAGCAGAACATCAGCGACATAGCAGA TTF1 ADXCRAD_BF700791_at ATGGAAACGAGCACGGGAGATCACACCCGCGGGGACGGACGTAAAGTCCAGAGATGCAACCC SEQ ID AGCGGAGAAGATGGACAGACATGACGTGGAATGCGGCAAAGCGGAACCAGAGCGACATCTAG NO: AGCGGGGAACGGACCAAGGAATCGGGGTCCCAAGACGTTGGGAAAAAGGGGCCCAGTTGTTA 2433 AAGGCCGGTCCACTGGAGCGGCCCGGGAGAAAAAACATCTTCCACTATACCTTTCAGGTTAA ACCCTGTGCCTTCAAC RHOH ADXCRAD_BM919440_at ATCCCTTGGGGGAACTGGTGATGAATAATTCCATCTTTGGATTAAAAAAGTGAAAATAGTCT SEQ ID CCCATAATTTTTGGGACCAATGAAGTTGAGT NO: 2435 RHOH ADXCRAD_BM919440_s_at GGATACAGTTATTGATGAGGCTTGGCCACTGGATGTTTTCACTAACTACACTCTACAAGTGA SEQ ID ACTCCTTGCCCAGGCCAGTTAGAAAATCCCT NO: 2436 LCP2 ADXCRAD_BP391263_s_at AACAGTAATAGTTATTGGTGTCACATAAAACTGATTTGTTTTTTACAGCCAAACCTCTGTCA SEQ ID GTCAGAGGCATTCATTAGTTTTATACATGTAATTTGAAAATCACTAAACCTCGTTTTCTCAG NO: CAGCAA 2439 FYB ADXCRAD_BG759248_at GTGTCTTCATCAAAAGGGTCCCCAGCTCCCCTGGGAGTCAGGTCCAAAAGCGGCCCTTTAAA SEQ ID ACCAGCAAGGGAAGACTCAGAAACATAAAGACCATGCAGGGGAGATTTCAAGTTTGCCCTTT NO: CCTGGAGTGGTTTTGAAACCTGCTGCGAGCAGGGGAGGCCCAGGTCTCTCCAAAAATGGTGA 2440 AGAAAAAAAGGAAGATAGGAAGATAGATGCTGCTAAGAACACCTTCCAGAGCAAACATACAT CAGGAACGAGTCGGCCTCAGGGCACTCCT FYB ADXCRAD_BX095265_at GATAAGCTTGCTAAACTTTCAGAGTGCCCTGAGACACTTCCAGCCATCCCTCCTCCTGCCTT SEQ ID CATTGGGGCAGACTTGCATTGCAGTCTGACAGTAATTTTTTTTCTGATTGAGAATTATGTAA NO: ATTCAATACAATGTCAGTTTTTAAAAGTCAAAGTTAGATCAAGAGAATATTTCAGAGTTTTG 2441 GTTTACACATCAAGAAACAGACACACATACCTAGGAAAGATTTACACAATAGATAATCATCC TTAATGGGA IKZF1 ADXCRAD_BG685498_at GTTAGTATAGAATTCTCGAAACTTGGGAATTCACAAATCAGGACTGGGGACTGCGAGACCAC SEQ ID AAATTTCTGATCGCATTTCTGATGGATGTGTCACACCTTTTCTGTCAAAACTAACATGTCTT NO: GGAGGTTAATCGACGTCCCTTGGGTGGACACACACA 2443 IKZF1 ADXCRAD_BG685498_x_at GTTAGTATAGAATTCTCGAAACTTGGGAATTCACAAATCAGGACTGGGGACTGCGAGACCAC SEQ ID AAATTTCTGATCGCATTTCTGATGGATGTGTCACACCTTTTCTGTCAAAACTAACATGTCTT NO: GGAGGTTAATCGACGTCCCTTGGGTGGACACACACA 2444 SNRPG ADXCRAD_AV757070_s_at GGTGGCAGACATGTCCAAGGAATATTGCGGGGATTTGATCCCTTTATGAACCTTGTGATAGA SEQ ID TGAATGTGTGGAGATGGCGACTAGTGGACAACAGAACAATATTGGAATGGTGGTAATACGAG NO: GAAATAGTATCATCATGTTAGAAGCCTTGGAACGAGTATAAATAATGGCTGTTCAGCAGAGA 2445 AACCCATGTCCTCTCTCCATAGGGCCTGTTTTACTATGATGTAAAAATTAGGTCATGTACAT TTTCATATTAGACTTTTTG SNRPG ADXCRAD_BX390183_s_at GAGGTTCCCAATGTTTCGTCCAGAAAAGTACTTTATTTATGCAAGTCAGGTGACTCTTAGGC SEQ ID CACAAAACCATTTGATGATAAACAGATTATCATTAGGTGCATATCTTATTGATATTTTGTGA NO: AATGTTATGCCTATGTTGCAAAAGTTGA 2452 NFATC3 ADXCRAD_CR741943_s_at GATCTGATGGGCTCTAACAGTGCTTACTGCAGCCTTGTGTCCACCACCAACTTCTCAGCATG SEQ ID TTTCTCTCCTTGGACCTTGGGTTTCCAACTCTGCAGCCTTCAGGTCTGGGGCCAGGAGTGGG NO: ACCCACCATTTGTGGGGAAAGTAGCATTCCTCCACCTCAGGCCTTGGGTAGATTTGGCAAAA 2460 GAACAGGAGCAGCATAGGCTGTTTGAGCTTTGG ATP2A3 ADXCRAD_CB047171_s_at AGCAGAAACCTGCACCAAGGATTGTCCCTATGTCTTGGCCCCTCCTAGAGCGTGTGCAGACT SEQ ID GATGATTTTATATGTAAATCAAGACTCACATCCCTTTCCTAGTCCCCCACATCCAAAGCCCC NO: TCAGCCTGCCTTGCAGACCAATGGGCTCCATGTTCTGTAGCCCCCTCCCCTACGCCTCACCC 2462 CTCCTCCCTCTCACAGGTTCTGGGCGGCCAGTGAGAGAAACGCAGTGGGGGAGGCAGGGAGT CTGGTGCCTGCAGAGATTCTCTGCTT NAP1L1 ADXCRAD_BP220549_at AGTTACTGGTACCACAGTGAGGTGAATAAAACGGGATTTTCAGAAGTTAGCCTGAATTTAAC SEQ ID TGTATTTTTAAATTTAACCTCCATTAACTAAGCATCTTTTCTTTGTGGTAGGGTCTACCTTC NO: TGCTTCCCTGGAAAGGATGAATTTACATCATTCGACAAGCCTATTTTCAAGTTATTTGNTGG 2470 TTGTTTGCTTGTTTTTGTTTTTGCAGCTAAAATAAAAATTTCAAATACAATTTTAGTTCTTA CAAGATAATGTCTTAATTTTGTACCAATTCAGGTAGAAG NAP1L1 ADXCRAD_BP220549_x_at AGTTACTGGTACCACAGTGAGGTGAATAAAACGGGATTTTCAGAAGTTAGCCTGAATTTAAC SEQ ID TGTATTTTTAAATTTAACCTCCATTAACTAAGCATCTTTTCTTTGTGGTAGGGTCTACCTTC NO: TGCTTCCCTGGAAAGGATGAATTTACATCATTCGACAAGCCTATTTTCAAGTTATTTGNTGG 2471 TTGTTTGCTTGTTTTTGTTTTTGCAGCTAAAATAAAAATTTCAAATACAATTTTAGTTCTTA CAAGATAATGTCTTAATTTTGTACCAATTCAGGTAGAAG TOP1 ADXCRAD_BM541278_s_at TTTTTGCTATAATCATTAGTTTTAGAGGCATTGTTAGTTTAGTGTG SEQ ID NO: 2477 TOP1 ADXCRAD_BM541278_x_at AGCAGAATTTTTAATGTGAAGACATTTTTTGCTATAATCATTAGTTTTAGAGGCATTGTTAG SEQ ID TTTAGTGTGGTGGGCAGAGTCCATTTCCCACATCTTTTCCTCCAGGATCCTCCAATTTTTAT NO: CATGAATTTCCCTTTTAATCAACCTG 2478 PCBP2 ADXCRAD_AW294074_s_at GGAAAGTCTAATCCTCAATCTTTTGGGCACAAGTTTTATAAGGGCCAACCAAGCATGGAGTC SEQ ID AGGGAAAAATAGGATCGAGGGCCACAAA NO: 2486 USP7 ADXCRAD_CA439064_at GAAGGGCCTCGTGACACATCAGGTCACATCTCCAGTCACCTTATTTGTACACAGTTCTCTCC SEQ ID TGGAAAACCTTTCATTTCTTAAGAGTAAATGTGACTAGTTAGAGGCTAAAAAAAAAAAAAAA NO: AAGAAACAAGAGACCCTGCCCCCGCAAAACGGAATTAGAAGGAAAAGTACATCTCAGTGAAA 2489 CCTTGTTACAAATGCCAAGGTTTCCCAGGCCTGTTTCCAGGGAGAGTAGAATCTTCCTCCAC TTCCACGTAACTCACTGAATTATA FYB ADXCRAD_BX437100_at GAAAATTAATGCACAAAACCACTTATTATCATTTGTTATGAAATCCCAATTATCTTTACAAA SEQ ID GTGTTTAAAGTTTGAACATAGAAAATRATCTCTCTGCTTAATTGTTATCTCAGAAGACTACA NO: TTAGTGAGATGTRAGARTTATTAAATATTCCATTTCCGCTTTGGCTACAA 2517 FYB ADXCRAD_BX437100_x_at GAAAATTAATGCACAAAACCACTTATTATCATTTGTTATGAAATCCCAATTATCTTTACAAA SEQ ID GTGTTTAAAGTTTGAACATAGAAAATRATCTCTCTGCTTAATTGTTATCTCAGAAGACTACA NO: TTAGTGAGATGTRAGARTTATTAAATATTCCATTTCCGCTTTGGCTACAAWTTATGAAGAAG 2518 TTGAAGGTACTTCTTTTAGACCACCA 41888 ADXCRAD_BG284913_at GGAGTGGCTTTTCTGGAAACAACACAAGACAACAGAAAACAGGTGTACACATATCTCTCATT SEQ ID CTCTTAAGCCAAGAAGTGTGCTTCCCTAGCTGAAGTGTAGATGGTCGTGTAGGGGTGGGTGG NO: AAAATCATGTGGCATACAGGTGTGGGTGTAATAT 2533 41888 ADXCRAD_BG284913_x_at GGAGTGGCTTTTCTGGAAACAACACAAGACAACAGAAAACAGGTGTACACATATCTCTCATT SEQ ID CTCTTAAGCCAAGAAGTGTGCTTCCCTAGCTGAAGTGTAGATGGTCGTGTAGGGGTGGGTGG NO: AAAATCATGTGGCATACAGGTGTGGGT 2534 MDN1 ADXCRAD_BE777779_at TGTTAATCCCTAAAAAAGGCTATGCAGGTAATAATTCTGGAAAACTTATTTAAAACATTTTC SEQ ID CAAGGGTTGGTGGGTGTTCAAAAACACACCGGAGAAGAAAGAGCTTTTGAGAACAAGAAAGA NO: AACGAAGAAAAAAAAGAGAAAGAAAAAAAAAAGGGGGGGGGGAATAATTCGGGGAAGAAGAG 2538 ACTTTTAAAAGGGACAAGAGGTAAAAAGGGGGGAAAGAGAGGAAACGGGTGTGGACTTGG ATP2A3 ADXCRAD_BX328303_at AGGTCCAACTTTGCACCCGCGTTCTTGGTACCTGAGACCACCGACATCCTCAGGTTCCTGAC SEQ ID CGTGCGGCCTTCTACCCA NO: 2544 ATP2A3 ADXCRAD_BX328303_x_at AGGATGTCCTTTCCCGGGAGACAAGTCGNGAAAGCCTGGCTGGACTGCCTCAGCCCCGCGCG SEQ ID CCTNCTGGACTCAGGGTTCCCCGTCCTGAGCTCNGGGAGATGTCAGAGTCACACTGCCGCCC NO: GGTCTGCCACGCAGAGGTCCAACTTTGCACCCGCGTTCTTGGTACCTGAGACCACCGACATC 2545 CTCAGGTTCCTGACCGTGCGGCCTTCTA HNRNPA1 ADXCRAD_CN296684_s_at GAACTGATAGTTACTGTTGTGACCTGAAGTTCACCATTAAAAGGGATTACCCAAGCAAAATC SEQ ID ATGGAATGGTTATAAAAGTGATTGTTGGCACATCCTATGCAATATATCTAAATTGAATAATG NO: GTACCAGATAAAATTATAGATGGGAATGAAGCTTGTGTATCCATTATCATGT 2549 CD3D ADXCRAD_BX457462_s_at CGTGGCTGGCATCATTGTCACTGATGTCATTGCCACTCTGCTCCTTGCTTTGGGAGTCTTCT SEQ ID GCTTTGCTGGACATGAGACTGGAAGGCTGTCTGGGGCTGCCGACACACAAGCTCTGTTGAGG NO: AATGACCAGGTCTATCAGCCCCTCCGAGATCGAGATGATGCTCAGTACAGCCACCTTGGAGG 2553 AAACTGGGCTCGGAACAAGTGAACCTGAGACTGGTGGCTTCTAGAAGCAGCCATTACCAACT GTACCTTCCCTTCTTGCTCAGCCAATAAAT 41888 ADXCRAD_BQ941634_at ATCACCACCATTCTGCTGTTCAGTGTCTCTTGAGAGAGCCTCTTTGCATGTTTTCCAGAATC SEQ ID TGTGTGTGTTTTTCCTTTCTTCTCCTTTGTTCTTTTTGCTCAAAGGTGTGACCAGTCATTGC NO: CCCCTCTGGGGCTTTCATTCTCCAGGAGAAACATCCCAGAACCAGCACTGTTTAGCCTGATA 2554 CCTTTCTAATGTCCATGTCAATTTTCAATAA NAP1L1 ADXCRAD_CX870261_s_at CAAGGGACGTGGGACAGTTCGTACTGTGACTAAAACAGTTTCCAATGACTCTTTCTTTAACT SEQ ID TTTTTGCCCCTCCTGAAGTTCCTGAGAGTGGAGATCTGGATGATGATGCTGAAGCTATCCTT NO: GCTGCAGACTTCGAAATTGGTCACTTTTTACGTGAGCGTATAATCCCAAGATCAGTGTTATA 2555 TTTTACTGGAGAAGCTATTGAA SHMT2 ADXCRAD_BP384660_s_at AACAAGACTTAGAAGGAGGGCCCAGGCACTTTCTGTTTGAACCCCTGTCATGATCACAGTGT SEQ ID CAGAGACGCGTCCTCTTTCTTGGGGAAGTTGAGGAGTGCCCTTCAGAGCCAGTAGCAGGCAG NO: GGGTGGGTAGGCACCCTCCTTCCTGTTTTTATCTAATAAAATGCTAACCTGCCCTGAGTTTC 2559 CATTACTGTGGGT HMGB1 ADXCRAD_BX429991_at GTATGGTCTAACCTTTACCATAGGACTTTATTCTTTAAACTCCATTACATGTAAGGGCCGTT SEQ ID ATATTTTGCAGCCTCCACATTAAGAATACTTGGTATGCTTTCTCCAAAGCGGTGAGCTTATA NO: TACAAGACTGGCATATTAAAATTTTCCGCTACACTTACTCCAAGAAAGCTTTGGAATAGCAG 2572 TCTTAT BLM ADXCRAD_AV763452_x_at ACACACACACACTTAGCCAGGCATGGTGGTGCATGCCTGTAATCCCAGCTACTTCAGATTCT SEQ ID GAGGCAGGAAGAATCACTTGCCCCAGAGGCAGAGTTTGCA NO: 2573 GCN1L1 ADXCRAD_BQ890025_at TCCAGTTTAGCCATGGCTAGGGTCCTGGAACTATAATAAGCAAGGGTCCAGACTGGTGGGGT SEQ ID TTCCTCCTTTCTCCTGTGGCTTGGAACCTCTTGGGTTTGAAAAGCTGGGCGCCTACCNAAAC NO: CCTTTTTTTCCCTATAATCCCCGGAATTGGGGGGCAACAGAACGGTTGGGGAATCTCCTG 2576 RPS6 ADXCRAD_BQ955249_at ATCTGAGCATTTAGCCTAAGGCAGTTAACTCCTACAAAGTGTCCATGAAACCAATACATCTG SEQ ID AAAAGGCCTATGCTCCAATGCAGATCTGGAATCCATGAGCAGTTTTGGAGTACCGATCAGAT NO: TAATGAAGATACTTTAACAACCTGCCACCTAATCTGGTGGTAATAGGTAACGTTACCCCTGA 2578 ATTTGGCGGAATTGGCCAAGGAAAATAAAGATGGCAAGCTTACATCAAATTTTA HSPD1 ADXCRAD_BM313583_s_at AACAGCATGATTGGGTTAGGAATTTGCATAGGATGAGTTCAGTGGTGAGACTTTTGAAACTA SEQ ID CACACATCTACCTTGTTTTAGTCCTATTTTCAAAATTTTGGCATTGTGAGATTTTATTTACT NO: GTGTGAACCTAAAGTTACTGTTTAAGTACATGCCACGCAACTCTGTGTTATTAAGAAGCACT 2588 GTCTCAGAAGCTGTGTGTAAATTTAATATTAAGGCACTAAAGACCAAGCATAGGTACATGCC TGTA CYFIP2 ADXCRAD_AV725374_at GATATTTTGAATTGTATCTTGCGGGTCCCTGTGTTGAAGTGATAAACATTTGCATCTTATTA SEQ ID AAACTGCTTTCACACTTGTAGACCCCACAACTTACAACAATTAATTGGCCGTTGTTTTACAA NO: CGGCTGACTGGGAAACCCTTGCCGTCCCCAACTTTATTGCTTGT 2591 WDR59 ADXCRAD_AA393120_at CCCCTAGAAATCTCCTGGAAGAGAGGAAATCAGATCAACTGGGGCTGCCTCAGACCTTGCAG SEQ ID CAGGAATTCTCCCTGATCAATGTGCAAATCCGGAATGTCAATGTGGAGATGGATGCGGCAGA NO: CAGGAGCTGCACAGTGTCTGTGCACTGCAGCAACCATCGTGTCAAGATGCTGGTGAAGTTCC 2596 CTGCACAGT USP7 ADXCRAD_CA437914_at TGTGTACCTTGGAGTGACTTCCTTTCTCAACTTCCACTGCAGTGTGTGTGCCTTCTGCTCTG SEQ ID AGAGCTGCCTTGTGACCCGTGTGATAGAAAGCAGGGAGTGAGGGTCCCCGCGGACCTGGCCC NO: TTCCCTCCTTCCTCCCCCAGAAAGAGGAGTTAGAGCAGGGGTGCGAGAGCCGTTCGCTGTGG 2597 GTTTGTCTTTGAACAAACATTAAGGTGTCTTGTTTTTGTTCTGGGCTGGGGGTTGGCTGTAG TCTTAGGTAACTGAAAGTTCCTACTCTCCCTTAAG HMGB1 ADXCRAD_DN601918_x_at GATGCTTCAGTCAACTTCTCAGAGTTTTCTAAGAAGTGCTCAGAGAGGTGGAAGACCATGTC SEQ ID TGCTAAAGAGAAAGGAAAATTTGAAGATATGGCAAAAGCGGACAAGGCCCGTTATGAAAGAG NO: AAATGAAAACCTATATCCCTCCCAAAGGGGAGACAAAAAAGAAGTTCAAGGATCCCAATGCA 2603 CCCAAGAGGCCTCCTTCGGCCTTCTTCCTCTTCTGCTCTGAGTATCGCCCAAAAATCAAAGG AGAACATCCTGGCCTGTCCATTGGTGATGTTGC PTMA ADXCRAD_BG706596_at GGATGGACGATGACCGATGACGGAAGCTGAGTC SEQ ID NO: 2606 PTMA ADXCRAD_BG706596_x_at TGGACGATGACCGATGACGGAAGCTGAGTCAGCTACGGGCAAGCGGGCAGCTGAAGATGATG SEQ ID AGGATGACGATGTCGATACCAAGAAGCAGAAGACCGACGAGGATGACTAGACAGCAAAAAAG NO: GAAAAGTTAAACTAAAAAAAAAAAAGGCCGCCGTGACCTATTCACCCTCCAATTCCCGTCTC 2607 AGAATCTAAACGTGGTCACCTTCGAGTACGAGAGGCCCGCCCGCCCACCGTGGGCAGTTGCC ACCCGCAGATGACACGCGCTCTCCACCAGCCAAGCCAAACCATGAGAAT PAICS ADXCRAD_CX785294_at GTGATGTCTGGGAACACTGCATATCCAGTTATCAGCTGTCCTCCCCTCACACCAGACTGGGG SEQ ID AGTTCAGGATGTGTGGTCTTCTCTTCGACTACCCAGTGGTCTTGGCTGTTCAACCGTACTTT NO: CTCCAGAAGGATCAGCTCAATTTGCTGCTCAGATATTTGGGTTAAGCAACCATTTGGTATGG 2609 AGCAAACTGCGAGCAAGCATTTTGAACACATGGATTTCCTTGAAGCAGGCTGACAAGA AKAP1 ADXCRAD_CN407762_s_at GCCTTGCCCAGTGGGTAGACAGCTACTACACAAGCCTTTGACCCCCATGCTGCTTCCTGAGA SEQ ID GTCTTTTTTTGCACTGTTGAAATTGGGCTTGGCACTCAAGTCAAAGATGAACATCGGAATAA NO: CAAACATTGTCCTCTCCAGAAAGTCCTTTCTTTCTCCATACTGTAGTCCTATTGAGAAGACA 2613 TTTCGTCTCTGAGAAAAAAAGGATGGAACTATGGGTTCTCTTCGCAAAGCCAAAGGATAGTG TTTAACAAGCCAGCT HMGB1 ADXCRAD_CX757597_at GAAAAGCGCCCATGTAACACAAACTGCCATTCAACAGGTATTTCCCTTACTACCTAAGGAAT SEQ ID TGTACCATTGCTCAGAATTGTAGGATTTACTATGTTGAAACTACAGGAGAGCCGGGCGCATG NO: GTCACCCTGTATCCAGCCTTTGGAGGCANGCGGCAATCACAGTCAGAATGAACATCTGCTAC 2620 TGTGAACCGCTCATAAATCAAAATACACTGTGCTGCCTGATCATATCGAGTAGCGAATGTGA CGAGGATCAGACATGCTGCCACGGA TTF1 ADXCRAD_BX457598_s_at AGGCCGGGACTGATATGCAGGAATCCCAGCCTACTGTGGGCTTGGATGATGAAACTCCACAA SEQ ID CTACTAGGAMCCTACTCACAAAAAAAAGTCTAAGAAAAAAAAGAAGAAAAAGTCCAATCACC NO: AGGAATTTGAGGC 2624 CBFA2T3 ADXCRAD_AW955147_x_at ATCTGTGTGCGTGGCTATCAGGAGTTCTAGGAACTCAGTGCAATACGGGAGTGACCCAGCTA SEQ ID CTTGACCAGCCACGAACAGCCCGCCAGAGGCCCTGAACTGGACGGTACGTTAATGTGAATGT NO: TATAGTCTTTGCAAAATCCCAAAGGATTTCATGAGGGTAATAAACAG 2638 NAP1L1 ADXCRAD_BQ884238_at GACTATGACCCAAAGAAGGATCAAAACCCAGCAGAGTGCAAGCAGCAGTGAAGCAGGATGTA SEQ ID TGTGGCCTTGAGGATAACCTGCACTGGTCTACCTTCTGCT NO: 2641 TOP1 ADXCRAD_CN309141_s_at GGAAGCTCAGAAAAGCATAAAGACAAACATAAAGACAGAGACAAGGAAAAACGAAAAGAGGA SEQ ID AAAGGTTCGAGCCTCTGGGGATGCAAAAATAAAGAAGGAGAAGGAAAATGGCTTCTCTAGTC NO: CACCACAAATTAAAGATGAACCTGAAGATGATGGCTATTTTGTTCCTCCTAAAGAGGATATA 2643 AAGCCATTAAAGAGACCTCGAGATGAGGATGATGCTGATTATAAACCTAAGAA NCKAP1L ADXCRAD_BM479866_at AACAGGGAGCCGACTTATAACACTAGGGCCCGGGGTCCCCCCTTTTTACCACACTTCCGACT SEQ ID GGCCAAAAACCGGCTTACCTTTCGGAACCCTTGGGGAAGGAGACACCTACTCCTCTCGGGGC NO: GCGGAACCTACATTGGTACAAAAT 2648 TMPO ADXCRAD_BX482009_s_at AAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTT SEQ ID TTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCA NO: TGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTAT 2649 TTTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGT GATTTCGCCTCAATAA EWSR1 ADXCRAD_CN353264_s_at GAAAAGTGGGACTAGACACGGTGTCCATATGGAGAGGAAAAATATACATAGAATATTTTTAA SEQ ID CAAAATGTATTCATTGTATAAATGGAATCCTTCTGTAACTTTGGTAACTGCATACTTGTTGT NO: TTGGTAATGAACCAGAGGAGGTATAATACTCTAGAATTGTGTAACATT 2650 FYB ADXCRAD_BF510133_at CAAGAGAAGAGTAATACGTGGTCCTGGGGGATTTTGAAGATGTTAAAGGGAAAAGATGACAG SEQ ID AAAGAAAAGTATACGAGAGAAACCTAAAGTCTCTGACTCAGACAATAATGAAGGTTCATCTT NO: TCCCTGCTCCT 2653 FYB ADXCRAD_BF510133_s_at TCCCTGCTCCTCCTAAACAATTGGACATGGGAGATGAAGTTTACGATGATGTGGATACCTCT SEQ ID GATTTCCCTGTTTCATCAGCAGAGATGAGTCAAGGAACTAATTTTGGA NO: 2654 FYB ADXCRAD_BF510133_x_at AGAGAAGAGTAATACGTGGTCCTGGGGGATTTTGAAGATGTTAAAGGGAAAAGATGACAGAA SEQ ID AGAAAAGTATACGAGAGAAACCTAAAGTCTCTGACTCAGACAATAATGAAGGTTCATCTTTC NO: CCTGCTCCTCCTAAACAATTGGACATGGGAGATGAAGTTTACGATGATGTGGATACCTCTGA 2655 TTTCCCTGTTTCATCAGCAGAGA 41888 ADXCRAD_CR743228_s_at TCAGGAGCCACAGCCATTTCTTAGAGGGTTTCAAAAGGACAGCCTTTGGCGCCTTTTCCTTC SEQ ID TAACCTTTGAGTCCAGCCCTTTCCAGTTTTCATTCACTCGAAGTAACTGCACTCAAGCTGTG NO: CTCAAAATCGGCAACGCATTTATTTACACCAAGCCCTTCCCATAAAACACAACTGCTGAAGA 2661 AAATAGCAGACGTTTCCCCTCTCTCTAACTCTGGGTATCCCACAGATGCAAAAGG SHMT2 ADXCRAD_CX788770_at ACTGCCAAGCTCCAGGATTTCAAATCCTTCCTGCTTAAGGACTCAGAAACAAGTCAGCGTCT SEQ ID GGCC NO: 2669 SHMT2 ADXCRAD_CX788770_s_at TCAGCGTCTGGCCAACCTCAGGCAACGGGTGGAGCAGTTTGCCAGGGCCTTCCCCATGCCTG SEQ ID GTTTTGATGAGCATTGAAGGCACCTGGGAAATGAGGCCCACAGACTCAAAGTTACTCTCCTT NO: CCCCCTACCTGGGCCAGTGAAATAGAAAGCCTTTCTATTTTTTGGTGCGGGAGGGAAGACCT 2670 CTCACTTAGGGCAAGAGCCA PTMA ADXCRAD_BM685721_s_at GAAAAACAATCTTATTCCGAGCATTCCAGTAACTTTTTTGTGTATGTACTTAGCTGTACTAT SEQ ID AAGTAGTTGGTTTGTATGAGATGGTTAAAAAGGCCAAAGATAAAAGGTTTCTTTTTTTTTCC NO: TTTTTTGTCTATGAAGTTGCTGTTTATTTTTTTTGGCCTGTTTGATGTATGTGTGAAACAAT 2679 GTTGTCCAACAATAAACAGGAATTTTA GTF3A ADXCRAD_BM729250_at ATATGTCTGTTTTTCCACTACCGTATCATTGCTGTTCACATGTAATGTGTTGTTTGTTCACA SEQ ID ACAAGCGCCTGGTTACACATTACACTGACGAATGTGCTGATGCTCCAGCCATGGCTTTGATG NO: CTTCTGTCATTTTTAACCTCTTCTATTAATATTTACTGCCTGTGCCATTCTTTTCCTTGTTG 2680 GCCATTCACAAGGCTTGGATAATCGTGTGACATTTTGAGAGCCATCAGATGTTACGTTTCTC AA BCL11A ADXCRAD_BU164469_x_at TATCTTTTACTATGGGAGTCACTATTTATTATTGCTTATGTGCCCTGTTCAAAACAGAGGCA SEQ ID CTTAATTTGATCTTTTATTTTTCTTTGCTTTTATTTTTTTTTTTATTTAGATGACCAAAGGT NO: CATTACAACCTGCGCTTTTTATTGAATTTGTTTCTGGCCTTTGTTAAGTTCTATTGGAAAAA 2684 CCACTGTCTGTGGTTTTTTTGGCAGTTGTCTGCATTAACCTGTTC PVRIG ADXCRAD_BX437785_at TGTCATCCCCTTACTTTAATTCTTGGGCCTCCAATAAGTGTCCCATAGGTGTCTGGCCAGGC SEQ ID CCACCTGCTGCGGATGTGGTCTGTGTGCGTGTGTGGGCACAGGTGTGAGTGTGTGAGTGACA NO: GTGACCCCATTTCAGTCATTTCCTGCTGCAACT 2685 PVRIG ADXCRAD_BX437785_x_at GCCCAGGGCCATGGAAGGACCCTTAGGAGTTCGATGAGAGAGACCATGAGGCCACTGGGCTT SEQ ID TCCCCCTCCCAGGCCTCCTGGGTGTCATCCCCTTACTTTAATTCTTGGGCCTCCAATAAGTG NO: TCCCATAGGTGTCTGGCCAGGCCCACCTGCTGCGGATGTGGTCTGTGTGCGTGTGTGGGCAC 2686 AGGTGTGAGTGTGTGAGTGACAGTGACCCCATTTCAGTCATTTCCTGCTGCAACTAAGTGAG CAACACAGTTTCTCTGATGT RNPS1 ADXCRAD_CX785467_at GATCGGAATGCAAATCTAGTTCTGGGTTCACTGCCTTCTCACTT SEQ ID NO: 2688 RNPS1 ADXCRAD_CX785467_x_at GATCGGAATGCAAATCTAGTTCTGGGTTCACTGCCTTCTCACTTGTCCCCTCGCCCCTAGTA SEQ ID ACTTTCTGTTCCTCACCA NO: 2689 PTPN7 ADXCRAD_BG388017_x_at TGAGCCCTGTGAGAGGCACGACTGTCTATGCCAATGAGGCTCGGTGGGGGGCTCTCAAGTGC SEQ ID CTGATCCTGCCCTGGGCTCAGAGCCAGCCCAGAGGGAAGCAACTGCACAGCCCCACAGGCCC NO: TCCTTGGGCACTGTCCCCCCAGACCCATCTCAGAGCTCAGAGGGTACAAGCTCCAGAACAGT 2705 AAGCAAGTGGGAAAATAAAGACTTCTTGGATGACTGAAGACAAAAAA ITGB7 ADXCRAD_BQ642465_at AAGGCTCTTTCTCCTTGGAGACAATGGGAACTGGAGGGTGAGAGGAAAGGTGGGTCTGTAAG SEQ ID ACCTTGGTAGGGGACTAATTCACTGGCGGAGTTCGGCCACCACCCTACTTCATTTTTAAAGG NO: GACACCCAAGAGGGGCTGCTTTCCATTGCCTGGAACCCTTGAATTCCATCTGGGGCCTACCC 2713 CCAACCCAAAGAAAAACAAATAAAAGCCCTTAACCCCCCGGGAGAAAAGAAAGNNAGAGGAA AAAAACCTCCCGAGGGCCATTCTAATTGTTCCGCGGTGGGCG ATIC ADXCRAD_BU189824_at TCTTCCCTTTCCGAGATAACGTAGACAGAGCTAAAAGGAGTGGTGTGGCGTACATTGCGGCT SEQ ID CCCTCCGGTTCTGCTGCTGACAAAGTTGTGATTGAGGCCTGCGACGAACTGGGAATCATCCT NO: CGCTCATACGAACCTTCGGCTCTTCCACCACTGATTTTACCACACACTGTTTTTTGGCTTGC 2723 TTATGTGTAGGTGAACAGTCACGCCTGAAACTTTGAGGATAACTTT AKAP1 ADXCRA2D_CN407756_s_at GGCTCATGCTGCCTGATGGCATCACCGTGGAGGTCATTGTGGTCAACCAGGTCAATGCCGGG SEQ ID CACCTGTTCGTGCAGCAGCACACACACCCTACCTTCCACGCGCTGCGCAGCCTCGACCAGCA NO: GATGTACCTCTGTTACTCTCAGCCTGGAATCCCCACCTTGCCCACCCCAGTGGAAATAACGG 2724 TCATCTGTGCCGCCC EWSR1 ADXCRAD_BG910390_s_at GAGCGCAGAGATCGGCCCTACTAGATGCAGAGACCCCGCAGAGCTGCATTGACTACCAGATT SEQ ID TATTTTTTAAACCAGAAAATGTTTTAAATTTATAATTCCATATTTATAATGTTGGGCACAAC NO: ATTATGATTATTCCTTGTCTGTACTTTAGTATTTTTCAC 2726 PTMA ADXCRAD_BP384625_x_at AGAGACGCCCCTGCTAACGGGAATGCTAATGAGGAAAATGGGGAGCAGGAGGCTGACAATGA SEQ ID GGTAGACGAAGAAGAGGAAGAAGGTGGGGAGGAAGAGGAGGAGGAAGAAGAAGGTGATGGTG NO: AGGAAGAGGATGGAGATGAAGATGAGGAAGCTGAGTCAGCTACGGGCAAGCGGGCAGCTGAA 2734 GATGATGAGGATGACGATGTCGATACCAAGAAGCAGAAGACCGACGAGGATGACTAGACAGC AAAAAAGGAA ANP32A ADXCRAD_CN349881_s_at TTGTAAATAGCAACCTAAAGGCGTATTTTGGCACTGGTCTGGGGACATTCCCCATCTCTCAT SEQ ID CCCTTTTCCCCCTTCACAGATGGTGGTGGGCTTCGCTCTACAAAGAGGACTCTGATGTTACT NO: CTTGAGCTTATGAGCCAGAGAGCTGAAAACCGCAGGCTTGTTGTGTTAAGTTACAAGGAAAA 2736 TGGATTTGGTAATTAAAATTAGAAGAAACACACCTTCAAACTTCAACTTCTTTAAAAGAAAA AAAAAACTGTCCTATCTTGTTCTGTAAAATATTAGAACGCTTTGT TRIM14 ADXCRAD_BI222503_at CACTTAACCCCTCAGCTATGAAAAGGCTTCCAGGAGTTTCCATGACATAACAAAACAACAAT SEQ ID ACAAGCGCCTCACCTTAGCATTCAAGGCTTGTCTAGTCTGCCCAACAATTACTTATCCTCAC NO: CTAGCTCCTACCAGTCTTCTTAGAGACTCTCCAGTCAGAACATGTGTCGCATAGTTCCACTC 2740 CACACCTCTCTGCTGACAGCACATTCATGCAGACAAGTCTTTCCACTGTCTCAGACTTCCGC AGGCTTACCTGCGCAGGCAAGTCTAACCAA EWSR1 ADXCRAD_BG619847_at ATAATTATGGGCTCACTTCCTACTGGAGATGTTGAAAGTCTAAATCGGTTTGACCATTTTGA SEQ ID TTGATGGCACAATCTGGTTTAGAAAACTTTGTTTAGATCAATGACATAACCCTGCTGCCTCT NO: GCCTGCCCTTCCCCTCCCTTCTCCCATCCCCTTTTCCCTATCTGGTGTCTGTACTTTGATGA 2747 AGGTGAGCTATAATATTGGTGGTTAATATAATCCAGAAGGCTTAGTTCTGTGTGT CHD7 ADXCRAD_CN341021_s_at GGATATAAACACTTTGACAGGAGAAGAAAGGGTGCCTGTTGTCAATAAACGAAATGGGAAGA SEQ ID AGATGGGTGGAGCTATGGCGCCTCCAATGAAGGATCTACCCAGGTGGCTGGAAGAAAATCCT NO: GAATTTGCAGTTGCTCCAGACTGGACTGATATAGTTAAGCAGTCTGGTTTTGTTCCTGAGTC 2748 GATGTTTGACCGCCTTCTCACTGGGCCTGTAGTGCGGGGAGAGGGAGCGAGCAGAAGAGGAA GAAGGCCCAAAAGTGAGATCGCCAGAGCAGC IKZF1 ADXCRAD_BM456472_s_at GTGTGGTGATTGTTCAGGTCGAATCTGTTGTATCCAGTACAGCTTTAGGTCTTCAGCTGCCC SEQ ID TTCTGGCGAGTACATGCACAGGATTGTAAATGAGAAATGCAGTCATATTTCCAGTCTGCCTC NO: TATGATGATGTTAAATTATTGCTGTTTAGCTGTGAACAAGGGATGTACCACTGGAGGAATAG 2749 AGTATCCTTTTGTACACATTTT SP110 ADXCRAD_NM_080424_s_at GACTTTGGCCAGGTAGGACTTGACTTAGAGGCAGAATTTGAAAAAGATCTCAAAGACGTGCT SEQ ID CGGTTTTCATGAAGCCAATGACGGCGGTTTCTGGACTCTTCCTTGACCCTGTTCTGTAAAGA NO: CTGAAGCATCCCCACCTCAGGATTCAGCTGATGGGACCCTGGCTTGGACTGTTGATTGCCAG 2760 TGAGTCTGGGATGTAATTGGCTGCCCTCAGGACCCAAACCCAGACACTTCATAGGATTATCA CACCCTCCATCTTTATT SH2D1A ADXCRAD_NM_002351_at TCATAATAAGTTGCATAGGTTTAATAATTTTTAATTATATGGCTTGAGTTTAAATTGTAATA SEQ ID GGCGTAACTAATTTTAACTCTATAATGTGTTCATTCTGGAATAATCCTAAACATATGAATTA NO: TGTTTGCATGTTCACTTCCAAGAGC 2763 SH2D1A ADXCRAD_NM_002351_x_at TCATAATAAGTTGCATAGGTTTAATAATTTTTAATTATATGGCTTGAGTTTAAATTGTAATA SEQ ID GGCGTAACTAATTTTAACTCTATAATGTGTTCATTCTGGAATAATCCTAAACATATGAATTA NO: TGTTTGCATGTTCACTTCCAAGAGCCTTTTTTTGAAAAAAAGCTTTTTTTGAATCATCAAGT 2764 CTTTCACATTTAA CD247 ADXCRAD_NM_198053_at AGAGGAGGCCGTTGATTCACTTCACGCTTTCAGCGAATGACAAAATCATCTTTGTGAAGGCC SEQ ID TCGCAGGAAGACCCAACACATGGGACCTATAACTGCCCAGCGGACAGTGGCAGGACAGGAAA NO: AACCCGTCAATGTACTAGGATACTGCTGCGTCATTACAGGGCACAGGCCATGGATGGAAAAC 2773 GCTCTCTGCTCTGCTTTTTTTCTACTGTTTTAATTTATACTGGCATGCTAAAGCCTTCCTAT TTTGCATAA MFNG ADXCRAD_NM_002405_at ACGGGTCCCAGCCAATTGTGATGATCCTTTTTGCTCATTTCCCAGCCTTTCTTGCTGTTAGG SEQ ID GGCTACCATGGGACCAGCTCTGGCCAGAGGGAACTAAGCAAATCCAATAGAGATGTTTCTGG NO: GGAAGGTTTTGCAGCCCACTCCCCATCTTCCTGCTATAAATGTGGGTGTGATGGCTGGATCT 2775 GGGGCAGCCACCTTGCTACCATGAAGGAAAGGCCAAGACAATCATCCACAGCTATTCCCTCC AGCATCTGGTTCTGTACAAAAATTA CD28 ADXCRAD_NM_006139_at TATACAGGGAAGTCCGTTTTCACTATTAGTATGAACCAAGAAATGGTTCAAAAACAGTGGTA SEQ ID GGAGCAATGCTTTCATAGTTTCAGATATGGTAGTTATGAAGAAAACAATGTCATTTGCTGCT NO: ATTATTGTAAGAGTCTTATAATTAATGGTACTCCTATAATTTTTGATTGTGAGCTCACCTAT 2776 TTGGGTTAAGCATGCCAATTTAAAGAGACCAAGTGTATGTACATTATGTTCTACA 41888 ADXCRAD_AF403061_s_at TAATCCATGGCTGTGTACTGAATAGTATTCCCCGCTACAGCTGGACTGGACTCCATTTAGCC SEQ ID TT NO: 2780 BCL11A ADXCRAD_BM193618_at GAAGCTATAGATCTCAAGAGTGCCTGTGTCCTACAAGGAACACATATTTCACAACTGATTCA SEQ ID TTTGCCCCTTACTCTGAGCACATGGGATAATAAAAGAAAGTTTTAGATCATCATTATCCAAA NO: GGATAACTTTGAATGCCCTTTTTCAGCATGCTTCTGAAAACATTTCATATCTCATTCAATGC 2785 CACATATAAATGGTATTTGCTGGACAGTGTGGAAAACAGAAACATCCGTGCTAAAAGCCAAT GGTAAACACCAAGTTTAAAAAATGGATTGCAAAGATCGCATGTCC PAICS ADXCRAD_AA902652_s_at TGGACAGCGAACATAAAGCTCTACTAGCTAACAAATAGGTCTTAATGATAAAAACGTGGGCC SEQ ID TTCAGAGAACTAAAGGTACCAATGTGTGGCAGTCCAAAATTACGAGGAAAATGAGTTCCCTT NO: CATGGGTCACATCAGCAATT 2798 ANP32A ADXCRAD_T67821_at TTTAATGAAGATACACCACTGAGTCTTGCTTTAAGACCAAAAATATCCAAACATAGTATCAC SEQ ID ATTATATATATCTCATANGAAAAGCTATTCTATCAGGNAACAAAAATGAAGCTTCCCCCTCA NO: CCTAGCAGTTCATCTGGGAATGCATCTTGGAAAAGATCCAATGGCCTGTTGGACTCAAAGAA 2799 GCCATCCCCAAAAAAATTGTATAAAAGGGTTTATTGAAATTTATCCAATGACCAACCGG ANP32A ADXCRAD_T67821_x_at TTTAATGAAGATACACCACTGAGTCTTGCTTTAAGACCAAAAATATCCAAACATAGTATCAC SEQ ID ATTATATATATCTCATANGAAAAGCTATTCTATCAGGNAACAAAAATGAAGCTTCCCCCTCA NO: CCTAGCAGTTCATCTGGGAATGCATCTTGGAAAAGATCCAATGGCCTGTTGGACTCAAAGAA 2800 GCCATCCCCAAAAAAATTGTATAAAAGGGTTTATTGAAATTTATCCAATGACCAACCGG PCBP2 ADXCRAD_AA504356_at TGACAGAGTTGGTTTAGGACTAGTGGATGGCATCATGTCAAGTTGTGGATAATGTCACGGGT SEQ ID NO: 2808 PCBP2 ADXCRAD_AA504356_s_at TGTTAGTCCTGGCTAGTCACTCATAACCTATGAATTTAAATTATCTTAGGGCCTCTATTTTT SEQ ID TAATCTGTAAAATGAGGGGATCAATGTGTTACAGATTAGTTGATCCTTAAGGTTCCTTCCAA NO: ATCTAAGCATGTCACTTCCTACTCCTGATAGTGCTGGTGGGGAGCAGAAAGGATACGGCCAG 2809 GAATAGAAAAAAGGGTAAAGAAACTTGGTTGACAGAGTTGGTTTAGGACTAGTGGATGGCAT CATGTCAAGTTGTGGATAATGTCACGGGTTGGCTGAGATATAC USP7 ADXCRAD_AI972599_at TTGGGAACCAAATGGCTCCAAAAGCCATTTGTCCTCCAAGCGACTACAGGGCAAAGTAGTGA SEQ ID GAATCATGCCCATCTCTCTGAAATAAACAATCAATTCAGGGGCTTCTTTCTACAGCCCAAAT NO: GTTGGCTAGATGGAACAGAAGTGACTCAATCTGTCAAATACAAAATCAGGAGTCACCCCTTC 2811 CAGTTTCAGTTCATCGTTCAAATGGAATCATATCCTTCCTCTGTTTGGCTTTTCTATGGGAA CTGCGC PAICS ADXCRAD_AU121975_at TGCTACCACACCCAATTATGAATTTCATCATTAGTTTCTTAGTAGAGTCCACATGTCCTCAG SEQ ID TAGTAAGTTCATCAGTGCTAAATATTT NO: 2824 PAICS ADXCRAD_AU121975_x_at TTAAGAGCCAAGTTCTCACTGTCTCCCAGGCTGGAGTGCAGTGGCATGATTATGGCTCCCTG SEQ ID CAGCCTTGAACTCCTGGACTCAAGCTGCAGCCTCTCGAGTAGCTGGGTGCATGTGCTACCAC NO: ACCCAATTATGAATTTCATCATTAGTTTCTTAGTAGAGTCCACATGTCCTCAGTAGTAAGTT 2825 CATCAGTGCTAAATATTT CALML4 ADXCRAD_AI348378_at AGATCTTGAAAGTTTTATGTGTTTAAAATTGAAATTGTCTAAAAAAATGCTCTTTCCACATT SEQ ID AATTTAGTTAGGATATATTTTCACTCCATTTCAGACACTTGACTCA NO: 2835 BLM ADXCRAD_AA769438_at TAGAGATACAGGAACAAGAGATTTAATATTATTTGAAATAATATTGAATACTGAATAATATC SEQ ID ATTGAATATATAATATTGAATATTATTATTTCGGCCAGGTGTGGTGGCTCACGTCTTTAATC NO: TCAGCACTTTGGGAGGCTGAGGGAGGCAGATCACTTGAGCCCAGGAGTTTGAGACTAGCCTG 2843 GGCAACACAGGGAGAGCCCATCTCTCTCTCTCTCTCTTTTTTTTTAAATTCATTACATAAAA ACAGATTGGGGCAACGGTTTGTTTATTTACTTGCTTTTGACATCATATTTGC BLM ADXCRAD_AA769438_x_at GAGATACAGGAACAAGAGATTTAATATTATTTGAAATAATATTGAATACTGAATAATATCAT SEQ ID TGAATATATAATATTGAATATTATTATTTCGGCCAGGTGTGGTGGCTCACGTCTTTAATCTC NO: AGCACTTTGGGAGGCTGAGGGAGGCAGATCACTTGAGCCCAGGAGTTTGAGACTAGCCTGGG 2844 CAACACAGGGAGAGCCCATCTCTCTCTCTCTCTCTTTTTTTTTAAATTCATTACATAAAAAC AGATTGGGGCAACGGTTTGTTTATTTACTTGCTTTTGACATCATATTTGC USH1C ADXCRAD_NM_025034_at ACATGCACACATAGGATTTTACTTGAAAAAAATAATAAAGGAGACAGATATGTCAAATCTTT SEQ ID TTCAGGCACTAATAACATGTAAATGTAAAAGAACTAGAATCTTCTCCACATACCACCTCCCA NO: TCAGAAATCATGTCCTTGAAAGTGCTGTTGATAAAGAAATAGGGTTGCCTTTCCCCTATTCC 2848 TTAATCTAATTATTCCAGAAACAGCTGTCATTTTGGTTTTCATT CD53 ADXCRAD_AW293276_at TTGAACACTCAGTGCTGACCAGAGATTAACATAGGGCATGCAATACTAAAATTGGTTTGCAT SEQ ID TTCACTTTCTGCTTCAACGTTCAGTAAATCCATCATAGCCCTACCAAGTGCCAGGGCAGTTG NO: CTGGTCAGTGGTTGTCCTAGTCTTTCTCCACAAACCTGAAAAACCCTGGAGATTTCCAAACC 2849 CCTTCAGGAGCAGATAACATGAGGAGACAAGACCTCAGGGATTCAGTCTAGTTGGAAGATAG TTGTGGCTTCTTCTCAGAGCCTATTCTGGAGGTCCAAAT HSPD1 ADXCRAD_AW674195_at TTTTTATTACACAAAGGTTGTCACATAATTGGATACTTCTCTACTTTGTACACAATTATTCT SEQ ID CACTCTCCACAGAAAGGCTGCTTAACTTCTCATCTGGTGGTGGCAAGCACTAAAATCCTGAT NO: TTTAACAGAATAGTAGT 2850 HSPD1 ADXCRAD_AW674195_x_at AATGTTTTACACACATGCCAGCCTGCCCTTCAACTGGCTTTCAATTTTCAGTATCTTCTAAT SEQ ID CATGGAAATGCTAACACAATTATTAACTTTAAACAAATTTTTATTACACAAAGGTTGTCACA NO: TAATTGGATACTTCTCTACTTTGTACACAATTATTCTCACTCTCCACAGAAAGGCTGCTTAA 2851 CTTCTCATCTGGTGGTGGCAAGCACTAAAATCCTGATTTTAACAGAATAGTAGT ARHGAP15 ADXCRAD_AI510829_at GATAAATCTCACACACATACTTCCACTCATACCCACCACATGTATTATATTAGCAATATCAT SEQ ID ACTCTAGGTCTTCTGGTTTGAGTCAGTATAACATGATAGGCACATTTCTATGGAATTTCATG NO: CATTATTTTCTTTTAATGCTTATGAGGGTAAGTACCAAAATATCCATTTTTCATTCACAGAG 2854 TAGAATTATTTTTTGACTTTTTTTGTGATCTTTTGACCAACTCTCACATCCAGAAAATGTGC CATT RNPS1 ADXCRAD_NM_006711_at AATAAACCCAAGATCATCTGAGATGAATATTAATTTTATTCTCATTTTATAGATGAGGAAAT SEQ ID GGGAGTTTTAAAGACATTCAATAACTTTGGCCAAGGTCATTCAGCTATTAAATTTTAAGACC NO: ATAAACCAATTGGATTCCTGGAGGAATTC 2859 PAICS ADXCRAD_AB002325_x_at GTTGCAGTGAGCCTCGATCCTGTCACTGCACTCCA SEQ ID NO: 2861 THUMPD1 ADXCRAD_AL134904_at CAGCTTGTGTAACAACCGATTCTTACCAAATACAAATAAATATAAAAGACAACTTAAAAACA SEQ ID AACTGTATAATCAAAATCTTTCCGTAAAATAGCAGCTTTCACAAAGTAAAAACAATTTAGTT NO: CCACAGAGTTGTATGCTCTGTAGGCATATGGCCAATTTTCTTCCGAGTCCTT 2878 THUMPD1 ADXCRAD_AL134904_x_at CAGGTTACAACCGAACACAGGATTTTGTAACTGGGAAAGAACAGCTTGTGTAACAACCGATT SEQ ID CTTACCAAATACAAATAAATATAAAAGACAACTTAAAAACAAACTGTATAATCAAAATCTTT NO: CCGTAAAATAGCAGCTTTCACAAAGTAAAAACAATTTAGTTCCACAGAGTTGTATGCTCTGT 2879 AGGCATATGGCCAATTTTCTTCCGAGTCCTTTTGTCTTGCACTATCAA CALML4 ADXCRAD_AW025529_at ACCGCAGGTCGGACGCCATGACGTAACCTTTCTTCTCCTTGTCCACCATCAACATGGCTAGA SEQ ID AGAATTTCTTTCTTTGGGTCTTCTTGTTTTATTTGCATGTGCATAATGGTCAGAAAAGTGGA NO: GAAATCCAGCTCTCCATTTCCGTCTATCCCGTGGGTCTGCAGGTGCCGCTGCACCTCCCCTG 2902 GCGTTGGGCTGGCCCCCAGGCACCTCATGGCCACCATGAGGTCGGGGGCTTTATCTTCCCCC TCTGCTGCTGTCATACAAGGAGAAGCATTTCTTGTCTCATTAATTT

TABLE 12 Genes and corresponding Almac probesets predicting resistance to oxaliplatin. There can be multiple Almac IDs/probesets associated with a given gene. Almac SEQ ID Gene Probe ID Probe Sequence NO ACTB AFFX- TGATATCGCCGCGCTCGTCGTCGACAACGGCTCCGGCATGTGCAAGGCCGGCTTCGCGGG SEQ ID HSAC07/X00351_5_at CGACGATGCCCCCCGGGCCGTCTTCCCCTCCATCGTGGGGCGCCCCAGGCACCAGGGCGT NO: GATGGTGGGCATGGGTCAGAAGGATTCCTATGTGGGCGACGAGGCCCAGAGCAAGAGAGG 827 CATCCTCACCCTGAAGTACCCCATCGAGCACGGCATCGTCACCAACTGGGACGACATGGA GAAAATCTGGCACCACACCTTCTACAATGAGCTGCGTGTGGCTCCCGAGGAGCACCCCGT GCTGCTGACCGAGGCCCCCCTGAACCCCAAGGCCAACCGCGAGAAGATGACCCAGATCAT GTTTGAGACCTTCAACACCCCAGCCATGTACGTTGCTATCCAGGCTGTGCTATCCCTGTA CGCCTCTGGCCGTACCACTGGCATCGTGATGGACTCCGGTGACGGGGTCACCCACACTGT GCCCATCTACGAGGGGTATGCCCTCCCCCATGCCATCCTGCGTCTGGACCTGGCT ACTB AFFX- ACCACGGCCGAGCGGGAAATCGTGCGTGACATTAAGGAGAAGCTGTGCTACGTCGCCCTG SEQ ID HSAC07/X00351_M_at GACTTCGAGCAAGAGATGGCCACGGCTGCTTCCAGCTCCTCCCTGGAGAAGAGCTACGAG NO: CTGCCTGACGGCCAGGTCATCACCATTGGCAATGAGCGGTTCCGCTGCCCTGAGGCACTC 828 TTCCAGCCTTCCTTCCTGGGCATGGAGTCCTGTGGCATCCACGAAACTACCTTCAACTCC ATCATGAAGTGTGACGTGGACATCCGCAAAGACCTGTACGCCAACACAGTGCTGTCTGGC GGCACCACCATGTACCCTGGCATTGCCGACAGGATGCAGAAGGAGATCACTGCCCTGGCA CCCAGCACAATGAAGATCAAGATCATTGCTCCTCCTGAGCGCAAGTACTCCGTGTGGATC GGCGGCTCCATCCTGGCCTCGCTGTCCACCTTCCAGCAGATGTGGATCAGCAAGCAGGAG TATGACGAGTCCGGCCCCTCCATCGTCCACCGCAAATGCTTCTAGGCGG ACTB AFFX- TCTTGACAAAACCTAACTTGCGCAGAAAACAAGATGAGATTGGCATGGCTTTATTTGTTT SEQ ID HSAC07/X00351_3_at TTTTTGTTTTGTTTTGGTTTTTTTTTTTTTTTTGGCTTGACTCAGGATTTAAAAACTGGA NO: ACGGTGAAGGTGACAGCAGTCGGTTGGAGCGAGCATCCCCCAAAGTTCACAATGTGGCCG 829 AGGACTTTGATTGCACATTGTTGTTTTTTTAATAGTCATTCCAAATATGAGATGCATTGT TACAGGAAGTCCCTTGCCATCCTAAAAGCCACCCCACTTCTCTCTAAGGAGAATGGCCCA GTCCTCTCCCAAGTCCACACAGGGGAGGTGATAGCATTGCTTTCGTGTAAATTATGTAAT GCAAAATTTTTTTAATCTTCGCCTTAATACTTTTTTATTTTGTTTTATTTTGAATGATGA GCCTTCGTGCCCCCCCTTCCCCCTTTTTGTCCCCCAACTTGAGATGTATGAAGGCTTTTG GTCTCCCTGGGAGTGGGTGGAGGCAGCCAGGGCTTACCTGTACACTGACTTGAGACCA CRIM1 ADXCRAG_AC007401_at GGGCAGAAAAGCCATGTCGCCATTTACTTGACACCTTTCAGTGCCACACACACCCTTCTG SEQ ID CCCCTCCCCTGCCTAGTCCAGGGCTTCACACTGAGCCTTCCTATGACAATAGGGGCCGAA NO: CTGCCACTGGTTTCTGAGGCCTCAGTGTAAAGGGCAAATGCGACACCAATTCCAACAAAC 842 CTGTAAATGTCAATGGCTAAGTAGTAAAAGTTTCTGCAGAGGCCCCAGAGCTGGGATTGA TTCAGTTCCACCTCAGGTTTTTTCCTGAGTGAGAGGGAGAGACGTAACTTTGGAAT RRBP1 ADXCRAG_AF006751_s_at AGAAGAAGTTAACAAGTGACCTGGGGCGCGCCGCCACGAGACTGCAGGAGCTTCTGAAGA SEQ ID CGACCCAGGAGCAGCTGGCAAGGGAGAAGGACACGGTGAAGAAGCTGCAGGAACAGCTGG NO: AAAAGGCAGAGGACGGCAGCAGCTCAAAGGAGGGCACCTCTGT 843 CDC14B ADXCRAG_AF023158_s_at CATTGACGTGGCCTGCGATCTCAGTGACAATGATCTGCTTTCTGGATCTCACTGTTGCCT SEQ ID TTGGTTAGGGAACACAGAGTGCTTCTCCCGCAGCCCTACTGGAACACAGCAGAGTCTGTG NO: CCATGAAGCAGTTACAGAAACAGAATTGAT 845 SVIL ADXCRAD_CA396083_s_at GAAGCTTGAGATCTATCTCACCGACGAAGACTTCGAGTTTGCACTAGACATGACGAGGGA SEQ ID TGAATACAACGCCCTGCCCGCCTGGAAGCAGGTGAACCTGAAGAAAGCAAAAGGCCTGTT NO: CTGAGTGGGGAGACGCCAGAGGAGCCTCACGGTCACGTCCAACAACACCACTGCACCAGG 846 GAAATGGATAT CDC14B ADXCRAG_AF064104_at GTGTGTCAGATGGAGAGATCCCCTTAACCTAAGAGCCTTAAATAGCCCTGAAAGTACACT SEQ ID GGGACGGTTTGCGATGGAATTAAAATTGGAAGTGAATATTTTTAGGTGCTCTTGAAGCTT NO: TCTGGGGACTCAAAATTATCAAAAGTCAGGGACAGTCCGGAGGAAGAGCGTCTGCAAAAC 847 TGGGTTCCTAGAAGTATAGACGGACTTAGCTTTTTGTAGAATTTGGTGAGGAGCAGCGCC TCGTGAGAGCAGAATGGCCTGGCGTGGCCAGTGCTTC CDC14B ADXCRAG_AF064105_at AATTTCTTGGTCTCCGAAAACTCAGCTGTGACTGCTTTCCATTAACAGTTCCAGCTCTAT SEQ ID GTGTTTCCTCTAACGCTAAAGGCACAGCCCCCGGGAATCTACTGCTTCCTAAGAGTCTCC NO: ATGGAGTCTATTTTACAACCTCCTTTCCCTCCATGCTTCCGCGGAGGAGTCTATACTATC 848 TCTATAT LOXL2 ADXCRAG_AF117949_s_at GAAACTTGTCAGAAGGCATAGGAGTTGTGCGAGGGCTGGATGGGAAGTCTAGATTTAAAC SEQ ID AGCCACCAGGCAGCTTATCAAAGCAAGAGGGCATCCGTTCACAGGACAGGGGCTCCCAGC NO: AATTCCCAGTGGCAGTGGGGGGTGGCTGGCCCAAGCCCCAAGTCACCCAGACACAGGGGA 858 CTTCCCCTTGTGTCAACAGCATGCTAGGGCCCAGCAAACTAGAGGGTAGGTAGGACCACC TTGGCACCAA FOXN3 ADXCRAG_AF138861_s_at GGTTCATTTTAGTTTCAGATAGATGGCTTCACCAAAGAACTCTTGAAAGAATACTGATTA SEQ ID GGGAGGGGCAGGGAAGTAGGAGCTTATGGTATATTATAAGGCTGGGAAAAATCTATGATG NO: CAAACCCTTTCCACATAGTACT 865 YPEL5 ADXCRAD_CD103546_s_at GACTTCTGAGTACAGTTAAGTTCCTCCTATTTGCCACTGGGCTGTTGGTTAGAAGCATAG SEQ ID GTAACTGATTAAGTAGGTATGATACTGCATTTGAAATAAGTGGACACAAACTATCCTTTC NO: TCCACCATGGACTCAATCTGAGAACAACAGCATTCATTTCCATTCATTTCCATACTGGCT 868 TTTGATTATATGCAGATTCCTAGTAGCATGCCTTACCTACAGCACTATGTGCATTTGCTG TCACAATAAAGTA CRIM1 ADXCRAG_AF168681_x_at ACTAATGATAATCCATCTCCCTTCGCTGACTCTCTTTTCGGACTCAGCCCGCCTGCATCC SEQ ID AGGTGAAATAAACAGCCGTGTTGCTCACACAAAGCCTGTTTGGTGGTCTCTTCACACGGA NO: CGCACATGAAATTTGGTGCCGTGACTCGGATCGGGGGACCTCCCTTGGGAGATCAATCCC 869 CCTGTCCTCCTGCTCTTTGCTCCATGAGAAAGATCCACCTACGACCTCAGGTCCTCAGAC CGACCAGCCCAAAAAACAT DKK1 ADXCRAG_AF177394_s_at GTTATCTTGACTGACAAATATTCTATATTGAACTGAAGTAAATCATTTCAGCTTATAGTT SEQ ID CTTAAAAGCATAACCCTTTACCCCATTTAATTCTAGAGTCTAGAACGCAAGGATCTCTTG NO: GAATGACAAATGATAGGTACCTAAAATGTAACATGAAAATACTAGCTTATTTTCTGAAAT 870 GTACTATCTTAATGCTTAAATTATATTTCCCTTTAGGCTGTGATAGTTTTTG MAP7D1 ADXCRPD.6828.C1_s_at TTGCCTTGATTTGGTGGGGTACAGTGGATGTGAATACTGTAAATAGCTTGTGCTCAGACT SEQ ID CCTCTGCGTGGAGAGGGTGGGTGCAGGAGGCAGACCCTCCCCCCAAAGCCCCCTGGGGAG NO: ATCTTCCTCTCTCTATTTAACTGTAACTGAGGG 871 CAV2 ADXCRAG_AF260225_at GAAAATAGCAATGTGCTGCTCTAAGCATTAGAGGTTCCCAAGTCTGCGCTTCAGAATGGG SEQ ID ATTATCTGGGAAACCTGGTAGAGAAGACAGTTTGTTTTTCTTTTTAAAAAGTGTTGAGCT NO: GTGGTTTAGGGTATTAAATAATAAAAACTCATCTCTATTTTCCATATCCACATATTTATA 874 ATATTTTACTCTTTATGGGCAAAAATTTATTCTTTCAAACCACCCCCTACTATGCCTCAA CATGTCTATTACATTAAAATTATCTCATATGTAGAGCAAG SYNJ2 ADXCRAG_AF318616_s_at CTTGCAGTGCTGGAAATAGATCTCATTTTTAGGTTTTCTCTTCGTTCCAGATACCAAATA SEQ ID AATGGGACAGAGAATAAAATTTTTGTTAAAATATGTGCTCATCTCCTAAGTAGCTCTTCA NO: GAGTCTGACCGTAAGTAAAAACACACAGAATTGTGTTGACTGGGGGAGGTGAATCACAAA 875 AAAGTTACGAGGAGTTTAAGAGTTAAATATTATTTGATCGTGGCTGTCAAATTTAGTGAA C PPAP2B ADXCRAG_AF480883_at GCTCGTAACACAACTCTCATCTCAGGCTCTTCTAAAGAGCTTTTGTATTCTAAAGAGGAT SEQ ID TTTTCCATCAGAGAGGTAGGAGCTGTAGGAACCCCGAGGGCAGATAAGCAGCCCTCACTC NO: TAGATAAGGTATGCTGGGGGAGCTTACTGAGGGAATCCTGTACACAGCCCACATCAAAGG 878 AAGGCTGAGAATGGCCTGTGGCTCC TXNRD1 ADXCRAG_AJ001050_s_at CAAGTCCACCAGTCTCTGAAATTAGAACAGTAGGCACGGTATGAGATAATCAGGCCTAAT SEQ ID CATGTTGTGATTCTCTTTTCTTAGTGGAGTGGAATGTTCTATCCCCACAAGAAGGATTAT NO: ATCTTATAGACTTGTCTTGTTCAGATTCTGTATTTACCCATTTTATTGAAACATATACTA 880 AGTTCCATGTAT COL6A2 ADXCRAD_CV571242_s_at GAGTCGGCGCACTCCATGCGCAAGCAGAACGTGGTACCCACCGTGCTGGCCTTGGGCAGC SEQ ID GACGTGGACATGGACGTGCTCACCACGCTCAGCCTGGGTGACCGCGCCGCCGTGTTCCAC NO: GAGAAGGACTATGACAGCCTGGCGCAACCCGGCTTCTTCGACCGCTTCATCCGCTGGATC 887 TGCTAGCGCCGCCGCCCGGGCCCCGCAGTCGAGGGTCGTGAGCCCACCCCGTCCATGGTG CTAAGCGGGCCCGGGT PRSS23 ADXCRAG_AL832007_at AAAATAGGCAACCAGAAGCCTTCTGTCAGTGGAGTAGCCATTC SEQ ID NO: 891 PRSS23 ADXCRAG_AL832007_x_at AGAAGCCAGCTGAAGCCCACCAAAACCAAGATGGCCATGAGAGTGACCTCTGGTTGTCCT SEQ ID CACTGCTACACTCCCACCAGCACCATGACAGTTTACAGATGCCATGGCAATGTCAGGAAG NO: TTACCCTATATGGTCTAAAAGGGGAGGCATGAATAATCCACCCCTTGTTTAGCATATAAT 892 CAAGAAATAACCATAAAAATAGGCAACCAGAAGCCTTCTGTCAGTGGAGTAGCCATTCT WDR1 ADXCRAG_AL832280_at ATTAGTTCCCCACGGAGAAGGGATGGATAGTCTGTGCTTCGGGGGTCTAAGGAAGGCTTC SEQ ID CTGCAGGTGCTGGTACCTCCTTAGGTCTGGGGTGGTTCCTTCTAAGTTTCCTTACCCTGC NO: CTGCATCACCTCTGCCTCTTATGACCTCTGTGCAAAGACTGGGAAGGGTCACCCCCAATG 894 GCTGTGAACGAACCTGTTTGTGATTCTAAACAGGGCACGGGACCATCCTACAATAAAAAT TACCCAGCCTAAAATGCCAGTAGTGCCAGTAGTCCCTGTTTAGAA CAST ADXCRAD_BE538471_s_at AAATATCTTCGAGACTTGGGTGTTTGTTAATAACTAATAACTGGAGTAAGCTACAGGATC SEQ ID TAAAGCAGCCCTTTTTACAGTCTAGTTAGGAGAGAGAAAATAATTGCAAATATCCACTTA NO: GAGGCAAAGAAC 895 FLNB ADXCRAG_AL833551_at GTCAGGGACGTTGCCTGGGCCCAAATGTGTAGTGTGGTCTGGGCAGGCAGACCTTTAGGT SEQ ID TTTGCTGCTTAGTCCTGAGGAAGTGGCCACTCTTGTGGCAGGTGTAGTATCTGGGGCGAG NO: TGTTGGGGGTAAAAGCCCACCCTACAGAAAGTGGAACAGCCCGGAGCCTGATGTGAAAGG 900 ACCACGGGTGTTGTAAGCTGGGACACGGAAGCCAAACTGGAATCAAACGCCGACTGTAAA TTGTATCTT PLAUR ADXCRAG_AY194849_at AAATGCAAGCTTCCAGATCACACACTGAACACTAACCTTCTAGTCTTCTCCTAAACTTCA SEQ ID AAGGTTGCAACTATTTTGTTGTTCTAAGGAGACATCCCCACATTTCCCAGCATGCTTTGG NO: GAAAGGAGACGGATAGAAGATAACCTGATGGCCAGAACTCCCTGCATGCACTGCAGTGAG 903 GAATAAGGACAGGAGTGCACTTCCCCTGATGTGCTGGGGACCGGGGATAAAGGCTGGGCT CTATTTCCCGGGATGCCTCAGGACTGTCAGAAAAAGAGACAGAACTACCATTTCAATGGC RYBP ADXCRAG_AY228125_s_at TTGTGAAAACTATGAATCAGGGTATGAAATTCAAAACCTCCACCTGCCCATGCTGCTTGC SEQ ID ATCCCTGGAGAATCTTCTGTGGACATCGACCTCTTAGTGATGCTGCCAGGATAATTTCTG NO: CTTGCCATGGGCATCTGGCCACCAAGGAATTTCGCACCCTGACGATTACTCTTGACACTT 904 TTATGTATTCCATTGTTTTATATGATTTTCCTAACAATC NFIB ADXCRAG_BC001283_s_at CATGATAAGCTAGTTTTATTGGTTTAGTATTCTTGTTGTTTACGCATGGAATCACTATTC SEQ ID CTGGTTATCTCACCAACGAAGGCTAGGAGGCGGCGTCAGAGGTGCTGGGTGACAGAGCCA NO: TGAGCCAGCCATTTTATAAGCACTCTGATTTCTAAAAGTTAAAAAAAATATATGAAATCT 913 CTGTAGCCTTTAGTTATCAGTACAGATTTATTAAATTTCGGCCCTTAACCCAGCCTTTTC CAGTGTGTAACCCAGTTTGA TPM4 ADXCRPD.6315.C1_s_at ATGGCACCAGCTTTTTCAGCTCTCTTATTTTTTCCTTAAGTAGCATTTATTCCTAAGGTA SEQ ID GGCAGGGTATTTCCTAGTAAGCATACTTTCTTAAGACGGAGGCCATTTGGTTCCTGGGAG NO: AATAGGCAGCCCCACACTTTGAAGAATACAGACCCCAGTATCTAGTCGTGGATATAATTA 917 AAACGCTGAAGACCATAACCTTTTGGGTCAACTGTTGGTCAAACTATAG FKBP9 ADXCRAD_CD251162_s_at GCAGAGGCCAGCTGCCGCAAGACAGCAATGACAGTCCACCTGCCGACCTGATTCCTGCAT SEQ ID CATGGAATAACCACATGGCTACCTTCTATCCTCTGTTCCCAAATGGTGGTGGCACTTATC NO: CTGAAGTCGTCAATGATTTCCCTTTGAAACTACTTTATTTTACTAATTTAAACTATTTTG 923 TACTGATGTAGCCCTGAGGTAGTTCATGAAAATGCTGTGCACTCATTCCATGGAATAAAT GTTGGAAAGCTGATCTTTTCTGATATAA ITGA5 ADXCRAD_W52075_s_at GGAGGCCCAGTTCACCCTGATTTAGGAGAAGCCAGGAATTTCCCAGGACCCTGAAGGGGC SEQ ID CATGATGGCAACAGATCTGGAACCTCAGCCTGGCCAGACACAGGCCCTCCCTGTTCCCCA NO: GAGAAAGGGGAGCCCACTGTCCTGGGCCTGCAGAATTTGGGTTCTGCCTGCCAGCTGCAC 926 TGATGCTGCCCCTCATCTCTCTGCCCAACCCTTCCCNCACCTTGGCACCAGACACCCAGG ACTTATTTAA MVP ADXCRAG_BC008932_s_at GAGATGCAGGTAAAACTGCTCCAGTCCCTGGGCCTGAAATCAACCCTCATCACCGATGGC SEQ ID TCCACTCCCATCAACCTCTTCAACACAGCCTTTGGGCTGCTGGGGATGGGGCCCGAGGGT NO: CAGCCCCTGGGCAGAAGGGTGGCCAGTGGGCCCAGCCCTGGGGAGGGGATATCCCCCCAG 927 TCTGCTCAGGCCCCTCAAGCTCCTGGAGACAACCACGTGGTGCCTGTACTGCGCTAACTC CTGATTAATACAATG RRBP1 ADXCRAG_BC009700_x_at ACTCAGAATCAAAGCAAAAAGGCTGAAGGAGCCCCAAACCAGGGCAGAAAGGCAGAGGGA SEQ ID ACCCCAAACCAGGGCAAAAAGACAGAGGGAACCCCAAACCAAGGGAAAAAGGCAGAGGGA NO: ACCCCAAACCAAGGCAAAAAGGCAGAAGGAACCCCAAACCAAGGCAAAAAGGCGGAGGGG 928 GCCCAGAACCAGGGTAAAAAGGTAGATACAACCCCAAACCAGGGGAAAAAGGTGGAGGGG GCCCCAACCCAGGGCAGAAAGGCCGAGGGGGCTCAGAACCAGGCCAAAA AMOTL2 ADXCRAG_BC011454_s_at TCAGCCCCAGGAGCTATTGGTGGGTTTTAGCAGTTTTGTCTTTACCGTTTTTAGTTCTCC SEQ ID TTGATTCTTTGTTTTCTTCCTTTATCGTTTTTAGGTTTGGTATGTGTTGTTTTATTTCCA NO: TGGTTCCTCAAGTTTCCTTTTTAAACATTTGCATTTGCTGGACAATTGCAATTTTTTTTA 930 RNH1 ADXCRAG_BC011500_s_at GCCATGCTCTCACCCTGCATATCCTAGGTTTGAAGAGAAACGCTCAGATCCGCTTATTTC SEQ ID TGCCAG NO: 931 ACTN1 ADXCRAG_BC011987_s_at GGAAAGATTAACTATTTGCACCGAAATGTCTTGTTTTGTTGCGACATAGGAAAATAACCA SEQ ID AGCACAAAGTTATATTCCATCCTTTTTACTGATTTTTTTTTCTTCTATCTGTTCCATCTG NO: CTGTATTCATTTCTCCAATCTCATGTCCATTTTGGTGTGGGAGTCGGGGTAGGGGGTACT 934 CTTGTCAAAAGGCACATTGGTGCATGTGTGTTTGCTAGCTCACTTGTCCATGAAAATATT T CYP1B1 ADXCRAG_BC012049_s_at TTCAGGAAAATAACTTAGACTCTAGTATTTATGGGTGGATTTATCCTTTTGCCTTCTGGT SEQ ID ATACTTCCTTACTTTTAAGGATAAATCATAAAGTCAGTTGCTCAAAAAGAAATCAATAGT NO: TGAATTAGTGAGTATAGTGGGGTTCCATGAGTTATCATGAATTTTAAAGTATGCATTATT 935 AAATTGTAAAACTCCAAGGTGATGTTGTACCTC TMBIM1 ADXCRAG_BC013428_at GGTCCTAAGAGGAAGGTGACTTCTCTCTGTTTGTCTTAAGTTGCACTGGGGGATTTCTGA SEQ ID CTTGAGGCCCATCTCTCCAGCCAGCCACTGCCTTCTTTGTAATATTAAGTGCCTTGAGCT NO: GGAATGGGGAAGGGGGACAAGGGTCAGTCTGTCGGGTGGGGGCAGAAATCAAATCAGCCC 937 AAGGATATAGTTAGGATTAATTACTTAATAGAGAAATCCTAACTATATCACACAAAGGGA TACAACTATAAA MAPK1 ADXCRAD_CF143752_s_at TAAGGTGCCATGGAACAGGCTGTTCCCAAATGCTGACTCCAAAGCTCTGGACTTATTGGA SEQ ID CAAAATGTTGACATTCAACCCACACAAGAGGATTGAAGTAGAACAGGCTCTGGCCCACCC NO: ATATCTGGAGCAGTATTACGACCCGAGTGACGAGCCCATCGCCGAAGCACCATTCAAGTT 943 CGACATGGAAT PLAUR ADXCRAG_BC019258_x_at CAAGTGATCTGTACATCTCAGCTACTCAGGAGGTTGAGTCAGGGGAACCTCTTGAACCC SEQ ID NO: 946 ADAM9 ADXCRAG_BC027996_s_at TGGCTTTTGTTGGTTGTTGGATTGACTGTGATTTAAAATGTTAAAGATGATATAATGCAT SEQ ID CTTGTTCTGCTTCTAGGCTGAAAGGTCACTGAGGCAGAGCTGTTTGTACCTTGTATCCCC NO: TGGAATTTTGCCTAAACATTTGTGTACTCATAGGGTGGTAGGAGATAGTCCGCAGATGGT 952 CTAAAGAATGCCATGTGATACTGTGAGATGCCAAT VIM ADXCRAD_AL046837_s_at TTTTAAACTTGGCTGTATTGTGTACAACTATTATACCATCTTTTATAAACACAGTTTTTT SEQ ID AAGAAATTTCTTTTTGTAAGTTACAACATTCCACTGGATCCTTATATTGCCTGTAGTGGA NO: AGAGGGTCTTGTGTGTCTGCCCCTTCTAGTTTTCACTCATGCAGAAGCAACATAACCTTC 953 TGATTTGCACAATAAATNACATATATTTAGCAGGATTTTTATTTGCCGTGATATATAGGA TAATTTAGTCTTTGGCATGTGGC TPBG ADXCRAG_BC037161_s_at TATTCTCATGTACCTAAGTTGTGGAGAAAATAATTGCATCCTATAAACTGCCTGCAGACG SEQ ID TTAGCAGGCTCTTCAAAATAACTCCATGGTGCACAGGAGCACCTGCATCCAAGAGCATGC NO: TTACATTTTACTGTTCTGCATATTACAAAAAATAACTTGCAACTTCATAACTTCTTTGAC 958 AAAGTAAATTACTTTTTTGATTGCAGTTTATATGAAAATGTACTGATTTTTTTTTAATAA ACTGCATCGAGATCCAACCGACTGAATTGTTAA FNDC3B ADXCRAG_BC039297_s_at AACACAGACTACAGGTTCCGCGTATGTGCGTGTCGTCGCTGTTTAGACACCTCTCAGGAG SEQ ID CTAAGCGGAGCCTTCAGCCCCTCTGCGGCTTTTGTATTACAACGAAGTGAGGTCATGCTT NO: ACAGGGGACATGGGGAGCTTAGATGATCCCAAAATGAAGAGCATGATGCCTACTGATGAA 961 CAGTTTGCAGCCATCATTGTGCTTGGCTTTGCAACTTTGTCCATTTTATTTGCCTTTATA TTACAGTACTTCTTA GALNT2 ADXCRAG_BC041120_s_at AGAGCCCTTCGAGCAAAGCGTGCCGAAGTTAGTTGTCTTCTCTGTGGTGGTCCTTTCTTA SEQ ID TGTCCTCATAAAAGCTCAGATGATGGTATCTGTGAGTATGTTTTGCAAATTCAAAATATA NO: GTTTGGTAATTTTTTTTTCCAGTTGATTTTTAAAAAGAACTGCTGTACAGAGCTTGT 964 ALCAM ADXCRAG_BC041127_s_at TTGGAATAATTATAGTCACTATGACAAAATTACTTTGCCTAATGATAGCATATAGTTAAT SEQ ID GTTACTGTGCAAATAACTGTGCAAATGAATGACTTGAGAAGT NO: 965 MAP1B ADXCRAG_BC046114_s_at TTCAGTGACTGAAAAGGAGGTTCCCAGCAAAGAAGAGCCATCTCCAGTGAAAGCCGAGGT SEQ ID GGCTGAGAAGCAAGCCACAGATGTCAAACCCAAAGCTGCCAAGGAGAAGACGGTGAAAAA NO: GGAAACAAAGGTAAAGCCTGAAGACA 967 AMIGO2 ADXCRAG_BC047595_s_at GTGTCAATACCAAAATGTCTGAGTAACTTCTTAAATCCCTGTTCTAGCAAACTAATATTG SEQ ID GTTCATGTGCTTGTGTATATGTAAATCTTAAATTATGTGAACTATTAAATAGACCCTACT NO: GTACTGTGCTTTGGACATTTGAATTAATGTAAATATATGTAATCTGTGACTTGATATTTT 968 GTTTTATTTGGCTATTTAAAAACATAAATCTAAAATGTCTTATGTTATCAGATTATGCTA TTTTGTATAAAGCACCACTGATAGCA CDC42BPA ADXCRAG_BC050335_x_at GGGAAGATACTGCTTTAGCCTATCACTCCTTATTTTATTTTGTTTGGTTTTATGCCCTCA SEQ ID GTGTCTTAGGGAACTTTTTAAGAGATCCTCTGCTACCAAACAATGATGTGGATTCTTTTG NO: CACAGAAATATTTAAGGTGGGATGGTAAAAAATGTCACAAAAGACTCCTCACCAATACTT 971 TATGTTGATATCACTTAATATTAACCAGACTTTGCTGTATTGCAATA MICALL1 ADXCRAG_BK000466_s_at AGCTGGTGGGTTTTGCCCAAGAAAGGTCACGCGGCACATGCAGGGATTGGAACTCCCAGG SEQ ID CCAGGGCTCTAGGTCGCTCCCACCTTTTCATGTTTCTTTCTGTGGCCATGGGTATAGTGG NO: AAAGACATAAAGCTAAAGCCAACTTTTAATCCTGAATGCACTGCTTGCCAGGTAAATGCC 977 CTTGGTTGTGGTATCTTGTTGAGACTTAGTTTTCACAGAGGGATAATGAACCGTTGCAGA GGTTTATTGAGATCATT LPP ADXCRAG_BX648297_s_at GTAGGGTATGACTTGTGAGTCCACAAGGCCAGCAGTATATATGCTGAATGGACTGCTTAG SEQ ID CAGTAACACACTGGAAAAATCCAAAAAGAATGGATTTCAAGTTGGCAAAAAATGCATTAG NO: AAGTCAGCAGTGTGATGTGGTCAGGAGAACAACCAGAGTGACTGTGGGATGAGGTCTTGG 984 ATAGCTTTGTT CDH11 ADXCRAG_D21254_s_at TTGTTACTGCTGATTCTTGTAAATCTTTTTGCTTCTACTTTCATCTTAAACTAATACGTG SEQ ID CCAGATATAACTGTCTTGTTTCAGTGAGAGACGCCCTATTTCTATGTC NO: 986 TRAM2 ADXCRAD_BM789115_s_at TGGTGCCCTGAGCAACTGATAATGCAAATGTGGACAAAGTGTCTGTTTTCTACTCTAGCC SEQ ID TGTTCATATGGACCAAATTTCAACAAGGAACTCAAGGAAAATTTGTACCTGCCGTATTTA NO: TGCTTTCATGTAAAAAAGGGTTGGGGGGAGGGGTGTCTTTTTGCTTTTGGTGAACTTTTT 988 TTCAAAATCATTTTTCCACTGTTTCTGTCTGGTTTTAAAACAAATTACAGTTTTGTATGG ATTTT VCAN ADXCRAG_D32039_s_at GAAAATGCCAAGACCTTTGGAAAGATGAAACCTCGTTATGAAATCAACTCCCTGATTAGA SEQ ID TACCACTGCAAAGATGGTTTCATTCAACGTCACCTTCCAACTATCCGGTGCTTAGGAAAT NO: GGAAGATGGGCTATACCTAAAATTACCTGCATGAACCCATCTGCATACCAAAGGACTTAT 989 TC DNAJB1 ADXCRAG_D85429_at GTGTCTCACAAAAAAGTGTCAAGCTAAGAGTTGCTTTCCCTTCCCACTGAAACAGTTGAA SEQ ID GCGCTGAAAACAGGCTAGGGGCAGCCCTGCCAGTCCAGGAGAACTTTCTGCAATGACTAG NO: AACGTTCTATATACCGTTTACTTAAACATCTTACAAATTCAATAAAATTAGAATCAGTTC 990 CTCAGTCCTGCCACACTTCAGTTGCTTAGCAGCCACACATGTATGTGGCCAGTGGCAACT GTTGGACAAGTCAAGT MAP1B ADXCRAG_L06237_at AAGAGCCAAGTTCAAAGAACCCTAGCACAAATTTGCTTTGGGATT SEQ ID NO: 991 MAP1B ADXCRAD_BX643299_s_at GAAGTTCTGGCAAGATTGAAGTCTGATATTGCAGTAATGATATTTATTAAAAACCCATAA SEQ ID CTACCAGGAATAATGATACCTCCCACCCCTTGATTCCCATAACATAAAAGTGCTACTTGA NO: GAGTGGGGGAGAATGGCATGGTAGGCTACTTTTCAGGGCCTTGACAAGTACATCACCCAG 992 NGGTATCCTACATACTTCTTTCAAGA JAK1 ADXCRAG_M64174_s_at ATGAGCTGCTGACTTACTGTGATTCAGATTCTAGTCCCATGGCTTTGTTCCTGAAAATGA SEQ ID TAGGCCCAACCCATGGCCAGATGACAGTCACAAGACTTGTGAATACGTTAAAAGAAGGAA NO: AACGCCTGCCGTGCCCACCTAACTGTCCAGATGAGGTTTATCAGCTTATGAGAAAATGCT 996 GGGAATTCCAACCATCCAATCGGACAAGCTTTCAGAACCTTATTGA AHNAK ADXCRAG_M80899_s_at TCTAGCAATGACAGTGGGAATAAGGTTGGCATCCAGCTTCCCGAGGTGGAGCTGTCAGTT SEQ ID TCCACAAAGAAAGAGTAGCAGGCCTTTGTATGTGTGTACATATATATATATATAACAAAA NO: CATCAGCCTTGGGTGGTGTGTTCCTATATAAACTCCAAAGGGAAACACACCGACTGCCTC 999 AGCAATCATGCAAAGA KRT14 ADXCRAG_NG_002781_at ACCAGGTCATATGTGGCGTCTCCTAGGGTACAGAGAGATATTCATTCATTTCCTCACTCA SEQ ID TTTTCATGTGTGTCCATTCATTCACCAGATATTGAGTGCCGCTATGTCAGGCACTATGTT NO: AGGTTAAGGATTCCTAATGTTTTTGTGATCAGGGATTCCTTGGAGAATATTGAAAGCTAT 1000 AGATCTTTCCTTCTGCCCCTACCTTCAAATAAGCA COL5A2 ADXCRAD_CK824374_s_at AATGATGGTGCTAAAATTCTTCCTATAAAATTCCTTAAAAATAAAGATGGTTTAATCACT SEQ ID ACCATTGTGAAAACATAACTGTTAGACTTCCCGTTTCTGAAAGAAAGAGCATCGTTCCAA NO: TGCTTGTTCACTGTTCCTCTGTCATACTGTATCTGGAATGCTTTGTAATACTTGCATGCT 1002 TCTTAGACCAGAACATGTAGGTCCCCTTGTGTCTC CD59 ADXCRAD_BP396775_s_at CCTCGTGGGTTTATTATTACCTCATAGGGACTTTGCCTCCTGACAGCAGTTTATGGGTGT SEQ ID TCATTGTGGCACTTGAGTTTTCTTGCATGCTTGTTAGAGAAACCAAGTTTGTCATCAACT NO: TCTTATTTAACCCCCTGGCTATAACTTCATGGATTATGTTATAATTAAGCCATCCAGAGT 1004 AAAATCTGTTTAGATTATCTTGGAGTAAGGGGGAAAAAATCTGTAATTTTTTCTCCTCAA CTAG PPIC ADXCRAG_NM_000943_s_at CCCTTCCTCAAGTGGTGCTATTTTAAAACTAAAAAAAACTTTGAATTGGCTATTTTTTTA SEQ ID ATGCAATATTTTTTTTCTGAATTCATTATGATCCCCATATTGGGTAATGCTGAACATTTA NO: TCTGAAACAGATGAGGATATTATTATTTTGTATCCAAACAGAAATTCAGATAAAGGGAAA 1006 TTTGACTAGTGTAATCTGAGATATGTCATAGGGATTTCTTTCTGACAAAAGGGTGCTTTG CTGTTCTT GRB10 ADXCRAG_NM_001001549_s_at AAGCTGGCGGTAGATTTGTGATGTCACAGTGCAAACTGCAGTGACTGTAAATTGGCCTGG SEQ ID CGTGTATAAACGTTTTCAGGGAATGCAGAAGGTATTAATGAAGAGACAAAACCTTTATTC NO: CATGTGCTTTGCTTCATTCTGTACATAGCTCTTTGGCTCGTGAACCTAATTGTAAACTTT 1007 CAGGTATTTTTGTACAAATAAGGGACTGATGTTCTGTTTCTTGTAATT CAV2 ADXCRAG_NM_001233_s_at ATAAAACTGTTTGACTTCTCAAGTAACATGACTTCCTTATTTCTGAACAGTACTGGTTAC SEQ ID TTTCAAAATGAATTTTTATTGAGATTTTCCATTAACTATTTTTTTCAAAGACTCAAATTT NO: TGTACCAAGTAAATCCAGGCTTTATGTACAAACATGTTGTTTGTTTTATTTGGGGCTGGG 1009 GGAGGTATATGATGAGCAGACTTCTCGGAATTCATAATAA BCL6 ADXCRAG_NM_001706_s_at TTTTCAGTTTGTATATACCCGTACAACGTGTCCTCACGGTGCCTTTTTTCACGGAAGTTT SEQ ID TCAATGATGGGCGAGCGTGCACCATCCCTTTTTGAAGTGTAGGCAGACACAGGGACTTGA NO: AGTTGTTACTAACTAAACTCTCTTTGGGAATGTTTGTCTCATCCCATTCTGCGTCATGCT 1011 TGTGTTATAACTACTCCGGAGACAGGGTTTGGCTGTGTCTAAACTGCATTACCGCGTTGT AAA LOX ADXCRAD_CV574618_s_at TAGAAGGCAAAGCAAAACTCCCAATGGATAAATCAGTGCCTGGTGTTCTGAAGTGGGAAA SEQ ID AAATAGACTAACTTCAGTAGGATTTATGTATTTTGAAAAAGAGAACAGAAAACAACAAAA NO: GAATTTTTGTTTGGACTGTTTTCAATAACAAAGCACATAACTGGATTTTGAACGCTTAAG 1013 TCATCATTACTTGGGAAATTTTTAATGTTTATTATTTACATCACTTTGTGAATTAACACA GTGTTTCAATTCTGTAATTACATATTTGACTCTT LOXL2 ADXCRAG_NM_002318_s_at CACCCCTTGTTTTTCAAGATACTATTATTATATTTTCACAGACTTTTGAAGCACAAATTT SEQ ID ATTGGCATTTAATATTGGACATCTGGGCCCTTGGAAGTACAAATCTAAGGAAAAACCAAC NO: CCACTGTGTAAGTGACTCATCTTCCTGTTGTTCCAATTCTGTGGGTTTTTGATTCAACGG 1014 TGCTATAACCAGGGTCCTGG NT5E ADXCRAG_NM_002526_at CTTTGAACCACTTTGCAATTGTAGATTCCCAACAATAAAATTGAAGA SEQ ID NO: 1015 NT5E ADXCRAG_NM_002526_s_at GCAGCAAAATAATAGCCTCGGTTCTATGCATATATGGATTGCTATAAAAAATGTCAATAA SEQ ID GATTGTACAAGGAAAATTAGAGAAAGTCACATTTAGGGTTTATTTTTTACACTTGGCCAG NO: TAAAATAGGGTAAATCCTATTAGAAATTTTTTAAAGAACTTTTTTTAAGTTTCCTAAATC 1016 TGTGTGTGTATTGTGAAGTGGTATAAGAAATGACTTTGAACCACT MAPK1 ADXCRAG_NM_002745_s_at TTCTGTGCAGAGATGACTGTCCAAGTGCCACATGCCTACGATTGAAATGAAAACTCTATT SEQ ID GTTACCTCTGAGTTGTGTTCCACGGAAAATGCTATCCAGCAGATCATTTAGGAAAAATAA NO: TTCTATTTTTAGCTTTTCATTTCTCAGCTGTCCTTTTTTCTTGTTTGATTTTTGACAGCA 1017 ATGGAGAATGGGTTATATAAAGACTGCCTGCTAATATGAACAGAAA PSMD2 ADXCRAD_CF130280_s_at ACAGGGTTCCAGACGCATACAACCCCAGTGTTGTTGGCCCACGGGGAACGGGCAGAATTG SEQ ID GCCACTGAGGAGTTTCTTCCTGTTACCCCCATTCTGGAAGGTTTTGTTATCCTTCGGAAG NO: AACCCCAATTATGATCTCTAAGTGACCACCAGGGGCTCTGAACTGTAGCTGATGTTATCA 1018 GCAGGCCATGCATCCTGCTGCCAAGGGTGGACACGGCTGCAGACTTCTGGGGGAATTGTC GCCTCCTGCTCTTTTGTTACTGAGTGAGA VEGFA ADXCRAG_NM_003376_at ACGAAAGCGCAAGAAATCCCGGTATAAGTCCTGGAGCGTTCCCTGTGGGCCTT SEQ ID NO: 1022 VEGFA ADXCRAD_AF091352_s_at GCTGCTGCAATGACGAGGGCCTGGAGTGTGTGCCCACTGAGGAGTCCAACATCACCATGC SEQ ID AGATTATGCGGATCAAACCTCACCAAGGCCAGCACATAGGAGAGATGAGCTTCCTACAGC NO: ACAACAAATGT 1023 PPAP2B ADXCRAD_CD678016_s_at TAAACTGTGTCTCGACCTGTGTTATTTACATTAGCTGCTTAAAAAAGCATTGAGTTAATT SEQ ID TTTTTAAATATCAACTAAAATATCATAGTTCTGTGGTAGACATTGTTTTATAATGAAATA NO: ACTGCAACTAGAGAAAACTGTATAAAAACATTAAATTGTCAGTATTTTTGTAAGGTTCCA 1024 TTTTGTAAAGAGAATAATATTCAAAGACTTTTGTAGCATACAAAGTGAAAACTTGTATCT GCGAAACTATACTTGTATTAAATGTGCTTTT EGFR ADXCRAD_BX378635_s_at TCCTAATCTGTGTGTGCCCTGTAACCTGACTGGTTAACAGCAGTCCTTTGTAAACAGTGT SEQ ID TTTAAACTCTCCTAGTCAATATCCACCCCATCCAATTTATCAAGGAAGAAATGGTTCAGA NO: AAATATTTTCAGCCTACAGTTATGTTCAGTCACACACACATACAAAATGTTCCTTTTGCT 1026 TTTAAAGTAATTTTTGACTCCCAGATCAGTCAGAGCCCCTACAGCATTGTTAA GATA6 ADXCRAG_NM_005257_at ATGCTGTATGTGACTATAGATATTCATATAAAACAAGTGCACGTGAAGTTTGCAAAATGC SEQ ID TTTAAGGCCTTCCTTTCAAAGCATAGTCCTTTTGGAGCCGTTTTGTACCTTTTATACCTT NO: GGCTTATTTGAAGTTGACACATGGGGTTAGTTACTACTCTCCATGTGCATTGGG 1027 FOSL1 ADXCRAG_NM_005438_s_at GTGCCACTTTACCCACCTAGAACACTAACTCACCAGCCCCACTGCCAGCAGCAGCAGGTG SEQ ID ATTGGACCAGGCCATTCTGCCGCCCCCTCCTGAACCGCACAGCTCAGGAGGCGCCCTTGG NO: CTTCTGTGATGAGCTGATCTGCGGATCTCAGCTTTGAGAAGCCTTCAGCTCCAGGGAATC 1028 CAAGCCTCCACAGCGAGGGCAGCTGCTATTTATTTTCCTAAAGAGAGTATTTTTATACAA ACCTACCAAAATGGAATAAAAGGCTTGAAGCT LPP ADXCRAG_NM_005578_at AAATAAGTCATGTGTCCCAGCATAAGGCATCAGGTTGTTAGATGCTGGCATCTCTGCAGC SEQ ID TCAAAGATGTGGGTTCTTTTTCTTGTCATTAACACATTGTTATTTCTGTAGGACCAACTT NO: CTCTGATCAAAATTACTTTTCTGGGTATGTGCTGATTAAGGGGGTGGACTTATCAACACT 1031 ATAATTGTTCCCTATGAAAGATTCCACAGAGATGTTTATGGTGA BASP1 ADXCRAD_CN355199_s_at GCGTTTGATTCTGCCCACAGGGCCTGTGCCAAGGCAATCAGATCTTTATGAGAGCAGTAT SEQ ID TTTCTGTGTTTTCTTTTTAATTTACAGCCTTTCTTATTTTGATATTTTTTTAATGTTGTG NO: GATGAATGCCAGCTTTCAGACAGAGCCCACTTAGCTTGTCCACATGGATCTCAATGCCAA 1034 TCCTCCATTCTTCCTCTCCAGATATTTTTGGGAGTGACAAACATTCTCTCATCCTACTTA GCCTACCTAGATTTCTCATGACGAGTTAATGCATGTCCGTGGTTGGGTGCACCTGTA CORO1C ADXCRAG_NM_014325_s_at GCAAGGGAAAGTTACCCTGATCTTAGTTTGTAGCTTATGACTTATTTAATGAATGGATGC SEQ ID CCAGCCAAGCTCAGAGTAGGCGCCCAAAGCATTGTGGATTATTTTCCTGTTTTGTCTTTT NO: TTTTTTTTTTTTTTTAAGCCATGACATCCCAGAAGAGGACAGTGAATTACTCCTAGGTCG 1041 GCTCTTATAGAGTGGCCATAGTGTTCTGTCAAAA EHD2 ADXCRAD_BX369705_s_at CTCCTTTTCAGGGATGTCGTGGGCGGGGGAGGGGGTTCTTGGTGCTACAGCCCTCTCCCC SEQ ID ACCCCTAAAGGGACGCCGACGCTGTTTGCTGCCTTCACCACATATTAGTGCTTGACCCTG NO: GCAGGGGACCCCATGGAAAAGATGGGGAAGAGCAAAATACATGGAGACGACGCACCCTCC 1043 AGGATGCTCGCTGGGATTCCCACGCCCACCACTGTCCCCCACCCCATGGCTGGGAGGGGC CTCTGAACGGAACAGTGTCCCCACAGAGCGAATAAAGCCAAGGCTTCTTCCCA HK1 ADXCRAG_NM_033497_s_at GTGGGCATAGCATTAGCTGCTTCCTCCCCTCCTGGCACCCACTGTGGCCTGGCATCGCAT SEQ ID CGTGGTGTGTCAATGCCACAAAATCGTGTGTCCGTGGAACCAGTCCTAGCCGCGTGTGAC NO: AGTCTTGCATTCTGTTTGTCTCGTGGGGGGAGGTGGACAGTCCTGCGGAAATGTGTCTTG 1049 TCTTCCATTTGGATAAAAGGAACCAACCAACAAACAATGCCATCACTGGAATTTCCCACC GCTTTGTGAGCCGTGTCGTATGACCTAGTAAACTTTGTACCA COL6A2 ADXCRAG_NM_058175_s_at TGGTGGCCACCGTGTCCCTTGCTGCGGCTGCATCTTCCAGTCTCTCCTCCGTCTTCCAGT SEQ ID GGCCGCTCTCTTTATAAGAACCCTGGTCATTGAATTTAAGGCCCACCCCAAGTCCAGAAT NO: GACCTCGCAAGACCC 1050 MALT1 ADXCRAG_NM_173844_s_at ACATTATACTTCATGGTGATAGACTGAAGGCTGAATGTTTTCCCCTTAAGATTGGGAAGA SEQ ID AGGACAAGGATGTTCACTCGGCACTACTTCTATTCAGCATTGTACTTGAAGTTCTAGCCA NO: CAGCAGTTAGGTTAGGAATTCAAGGTTTGTTCAACA 1053 IL6ST ADXCRAD_CN265168_s_at AACAGTTGGCATGGAGGCTGCGACTGATGAAGGCATGCCTAAAAGTTACTTACCACAGAC SEQ ID TGTACGGCAAGGCGGCTACATGCCTCAGTGAAGGACTAGTAGTTCCTGCTACAACTTCAG NO: CAGTACCTATAAAGTAAAGCTAAAATGATTTTATCTGTGAATTCAGATTTTAAAAAGTCT 1054 TCACTCTCTGAAGATGATCATTTGCCCTTAAGGACAAAAATGAACTGAAGTTTCACATGA GCTATTTCCATTCCAGAATATCTGGGATTCTACTTTAAGCACTA PLOD2 ADXCRAD_BF971357_s_at AACAAAGTTGTTGAGCCTTGCTTCTTCCGTTTTGCCCTTTGTCTCGCTCCTTATTCTTTT SEQ ID TATGGGGGGAGGGTTATTTGCTTTTTTATCTTCCTGGCATAATTTCCATTTTATTCTTCT NO: GAGTGTCTATGTTAACTTCCCTCTATCCCGCTTATAAAAAAATTCTCCAACAAAAATACT 1056 TGTTGACTTGATGTTTTATCACTTCTCTAAGTAAGGTTGA EXT1 ADXCRAG_579639_s_at CGACTTTGAGGAATCCGGCTGAGTGGGGGAGGGGAAGCAAGAAGGGATGGGGGTCAAGCT SEQ ID GCTCTCTCTTCCCAGTGCAGATCCACTCATCAGCAGAGCCAGATTGTGCCAACTATCCAA NO: AAACTTAGATGAGCAGAATGACAAAAAAAAAAAAGGCCAATGAGAACTCAACTCCTGGCT 1058 CCTGGGACTGCACCAGACTGCTCCAAACTCACCTCACTGGCTTCTGTGTCCCAAGACTAG GTTG CYP1B1 ADXCRAD_AV717387_s_at TTTGTGTGTTTTTAGCTGTGACACAACTGTGTGATTAAAAGGTATACTTTAGTAGACATT SEQ ID TATAACTCAAGGATACCTTCTTATTTAATCTTTTCTTATTTTTGTACTTTATCATGAATG NO: CTTTTAGTGTGTGCATAATAGCTACAGTGCATAGTTGTAGACAAAGTACATTCTGGGGAA 1060 ACAACATTTATATGTAGCCTTTACTGTTTGATA VCAN ADXCRAD_CN312093_s_at GGAGCCTTAGAGGTCTTTAATCATTGGTTCGGCTGCTTTTATGTAGTTTAGGCTGGAAAT SEQ ID GGTTTCACTTGCTCTTTGACTGTCAGCAAGACTGAAGATGGCTTTTCCTGGACAGCTAGA NO: AAACACAAAATCTTGTAGGTCATTGCACCTATCTCAGCCATAGGTGCAGTTTGCTTCTAC 1063 ATGATGCTAAAGGCTGCGAATGGGATCCTGATGGAACTAAGGACTCCAATGTCGAACTCT TCTT FOXN3 ADXCRAG_U68723_at TTTTTCTGTCTATCAAAACTATTTGATCCAAGTGAAAAAAAAAAAAAAACTAGAAAGCTA SEQ ID CGGAACCTGCAATGCGGCCG NO: 1072 FOXN3 ADXCRAD_CR735795_s_at TGGACGTTGGACTGTTCATGCGCATCGGGTGTCAGTGACTCATGGAGAAGAAATGGGGTA SEQ ID AATTTTTAGTGATGTTGCTAATCATTGAATTCTGTTCTCTATTAAATTAAGAAAATGTTC NO: CAAAAGCCATAAGCCTGAAGATTGGCCCTGTGCACGCACGCACACACACACACACACACA 1073 CACACACACACACACACACGAAGGAGAGAGAGAGAAAACTGATGGGGAAAACAAGCTGTG TCTTCTTAACTGCCCAAGTGAAAAGCAACCAAGTCCAGGAAATTACAATAGCTGTT NFIB ADXCRAG_U85193_at GGGAATTCATGGATTATTAAGGTCCTTCAGGCCCTTG SEQ ID NO: 1076 NR3C1 ADXCRAG_X03348_s_at AAAGTGTCTTTTTACCTACGCAGTGAAATGTCAGACTGTAAAACCTTGTGTGGAAATGTT SEQ ID TAACTTTTATTTTTTCATTTAAATTTGCTGTTCTGGTATTACCAAACCACACATTTGTAC NO: CGAATTGGCAGTAAATGTTAGCCATTTACAGCAATGCCAAATATGGAG 1078 COL4A2 ADXCRAG_X05562_at CAAAGGCGAGGCTGGATTTTTCGGAATACCCGGTCTGAAGGGTCTGGCTGGTGAGCCAGG SEQ ID TTTTAAAGGCAGCCGAGGGGACCCTGGGCCCCCAGGACCACCTCCTGTCATCCTGCCAGG NO: AATGAAAGACATTAAAGGAGAGAAAGGAGATGAAGGGCCTATGGGGCTGAAAGGATACCT 1079 GGGCGCAAAAGGTATCCAAGGAATGCCAGGCATCCCAGGGCTGTCAGGAATCCCTGGGCT GCCTGGGAGGCCCGGCCACATCAAAGGAGTCAAGGGAGACATCGGAGTCCCT ZNF264 ADXCRAD_BP361385_s_at TCCATTGGGTGGGTTCTTTTGTACACCTTCTGTTTCTTTGCTTATTTTTTAACGCCAAAG SEQ ID AAAGACTCTCAGAGAATAGACAACTATATTCCAAAGTCATGGTTCTCTGGTGGTTTGTCT NO: TGACATTTGAATAGAAATGTTAAACTATCTGGGGGAATAGAAAGCCCACAGTCTTCTGAG 1091 TTGTGCTACACCAATATTTCTATGAACAGATCTTACAACTGAGAGTGATCTGCAGATTTT TCAGAGTCATGTTCTCCATGGAAATGTTTGTAAAATTCCCTAGCTCTCTG MAP1B ADXCRAD_AV721962_s_at TCCAGCACTGGAAAGAAGTGGTCTTGAGCCCAGCTGAGAAGCACTTCACACTCCTCTCTC SEQ ID TTGTTCTGAATGGTGTTTGTGTCAGTCTGCAGCTGTGTATGGTATTATGTCTTA NO: 1094 ALCAM ADXCRAD_CB160126_s_at ATTACCATCGATTCAGTGCCTGGATAAAGAGGAAAGCTTACTTGTTTAATGGCAGCCACA SEQ ID TGCACGAAGATGCTAAGAAGAAAAAGAATTCCAAATCCTCAACTTTTGAGGTTTCGGCTC NO: TCCAATTTAACTCTTTGGCAACAGGAAACAGGTTTTGCAAGTTCAAGGTTCACTCCCTAT 1095 ATGTGATTATAGGAATTGTTTGTGGAAATGGATTAACATACCCGTCTATGCCTAAAAGAT AA PYGL ADXCRAG_Y15233_s_at GTCTTTGCAGACTACGAAGCCTATGTCAAGTGTCAAGATAAAGTGAGTCAGCTGTACATG SEQ ID AATCCAAAGGCCTGGAACACAATGGTACTCAAAAACATAGCTGCCTCGGGGAAATTCTCC NO: AGTGACCGAACAATTAAAGAATATGCCCAAAACATCTGGAACGTGGAACCTTCAGATCTA 1096 AAGATTTCTCTATCCAATGAATCTAAC PTPRK ADXCRAG_Z70660_at TATTGAGCCAGCAGCTGTTGTACCTGTTACACTTGTGCAGAAAGATTTTAATGTGGGGGG SEQ ID TGGGAGACTTTTACATTTGAGAGGTAAAAGTATTTTTTTTATGAAGTTGTGTATCTTAAT NO: AAAAAGAACTGAATTAGTTTTTATTACTATATTAAAGCATCAACATTTCATGCCACATAA 1097 AATTATATTTAATAAGAACCAGATTGAAATGAGAACGTATTGGTGTTTGTACAGTGAACA TGCCACCTTTTTCCATGGTTTCAGGTAGTGCAGCTACCACATGTT LMNA ADXCRIH.3276.C1_s_at CCCAGAACTGCAGCATCATGTAATCTGGGACCTGCCAGGCAGGGGTGGGGGTGGAGGCTT SEQ ID CCTGCGTCCTCCTCACCTCATGCCCACCCCCTGCCCTGCACGTCATGGGAGG NO: 1099 CKAP4 ADXCRIH.293.C1_s_at CTTGTCCCCTCTTAAAGAGCAGTTGTCACCACCTGAACACCAAGGCATTGTATTTTCATG SEQ ID CCCAGTTAACTTATTTACAATATTTAAGTTCTCTGCTTCTGCATTTGGTTGGTTTCCTGA NO: AGCGCAGCCCCTGTGAATAACAGGTGGCTTTTCATGGATGTCTCTAGTCAGAG 1103 CD44 ADXCRAD_CN347079_s_at TCAACAGTCGAAGAAGGTGTGGGCAGAAGAAAAAGCTAGTGATCAACAGTGGCAATGGAG SEQ ID CTGTGGAGGACAGAAAGCCAAGTGGACTCAACGGAGAGGCCAGCAAGTCTCAGGAAATGG NO: TGCATTTGGTGAACAAGGAGTCGTCAGAAACTCCAGACCAGTTTATGACAGCTGATGAGA 1104 CAAGGAACCTGCAGA AHNAK ADXCRIH.2649.C1_s_at GTGGTCCCAGCCAGTTTGGTGCTGACGGTGAGAGGAAATTAGAATCTGTTTGCAAATTGT SEQ ID CCAACCCACCCCCTCAACATGAGGGGCTTCCATTTTCTGTGTTTTGTAAGGGAACTGTTT NO: CCTTCATGCCGCCATGTTCCTGATATTAGTTCTGATTTCTTTTTAACAAATGTTATCATG 1106 ATTAAGAAAATTTCCAGCACTTTAATGGCCAATTAACT RYBP ADXCRIH.2682.C1_at ACATCCCTCAGGCATGTATTCTGGAAATGGAATTCCTGTAACTTCCTGTGTCTGCAGTAT SEQ ID GCCCTACAATTAGTAGGCAGCGTGTAAAAACACTAGTGTAGATTATAAAGATATACATTA NO: AAAGAGGACCAGAAATACTTGGTATTCAGTGGCACAGAAAGCAGGTTAAACAAACAAAAA 1109 GCACAGTGTTACGCTTGCAAGTTTCCATTTGTTTTAATACCACGCAATCTTTCACACTCG TGCGTGTGCGCGCACACAGAGCTTACCTGACTTGCTCTGCTTGAGTCATGCAG MARCKS ADXCRIH.653.C1_s_at AGTGAATAGTCAAAAATCCTGTTAGCAAACTGTTATATATTGCTAAGTTTGTTCTTTTAA SEQ ID CAGCTGGAATTTATTAAGATGCATTATTTTGATTTTATTCACTGCCTAAAACACTTTGGG NO: TGGTATTGATGGAGTTGGTGGATTTTCCTCCAAGTGATTAAATGA 1112 RRAS2 ADXCRIH.3655.C1_at TTCTTTGTCAGTTAAAAGTGAACAGTGAGAATTAAATACTTATCTTTACATATACACAAG SEQ ID GTATGCTATGAAAGCATATCTGCTTACAAACATATAAAAATACTTGTTAACTAGTTTGAT NO: AAGAAAATAATGTATAAAAGTATATAGCAAAAACATTAATCATCTCTGACCCTGGAAAGA 1113 TCAATTCCATATTTTATAT TGFBR2 ADXCRIH.688.C1_s_at AGTCCACGTTCACAAAATGTGAAGGTGTGGAGACACTTACAAAGCTGCCTCACTTCTCAC SEQ ID TGTAAACATTAGCTCTTTCCACTGCCTACCTGGACCCCAGTCTAGGAATTAAATCTGCAC NO: CTAACCAAGGTCCCTTGTAAGAAATGTCCATTCA 1115 SDC4 ADXCRIH.1351.C1_s_at GATGGTGGGATATTTGTGTCTGTGTTCTTATAATATATTATTATTCTTCCTTGGTTCTAG SEQ ID AAAAATAGATAAATATATTTTTTTCAGGAAATAGTGTGGTGTTTCCAGTTTGATGTTGCT NO: GGGTGGTTGAGTGAGTGAATTTTCATGTGGCTGGGTGGGTT 1116 EPHA2 ADXCRIH.2345.C1_s_at TGGCCCAGCGCCAAGTAAACAGGGTACCTCAAGCCCCATTTCCTCACACTAAGAGGGCAG SEQ ID ACTGTGAACTTGACTGGGTGAGACCCAAAGCGGTCCCTGTCCCTCTAGTGCCTTCTTTAG NO: ACCCTCGGGCCCCATCCTCATCCCTGACTGGCCAAACCCTTGCTTTCCTGGGCCTTTGCA 1120 AGATGCTTGGTTGTGTTGAGGTTTT S100A11 ADXCRIH.305.C1_s_at AACTGGACACCAACAGTGATGGTCAGCTAGATTTCTCAGAATTTCTTAATCTGATTGGTG SEQ ID GCCTAGCTATGGCTTGCCATGACTCCTTCCTCAAGGCTGTCCCTTCCCAGAAGCGGACCT NO: GAGGACCCCTTGGCCCTGGCCTTCAAACCCACCCCCTTTCCTTCCAGCCTTTCTGTCATC 1121 ATCTCCACAGCCCACCCATCCCCTGAGCACACTAACCACCTCATGCAGG FLNB ADXCRIH.1727.C1_s_at GGGCCCATGGATTAACGCCCTCATCCCAAGGTCCGTCCCATGACATAACACTCCACACCC SEQ ID GCCCCAGCCAACTTCATGGGTCACTTTTTCTGGAAAATAATGATCTGTACAGACAGGACA NO: GAATGAAACTCCTGCGGCTCTTTGGCCTGAAAGTTGGGAATGGTTGGGGAGAGAAGGCAG 1127 CAGCTTATTGGTGGTCTTTTCACCATTGGCAGAAACAG CRIM1 ADXCRAD_BG621095_s_at AAAAAATTGTAGATGCTTGCTTTTTGTTTTTTCAATCATGGCCATATTATGAAAATACTA SEQ ID ACAGGATATAGGACAAGGTGTAAATTTTTTTATTATTATTTTAACAGATATGATTTATCC NO: TGAGTGCTGTATCTATTACTCTTTTACTTTGGTTCCTGTTGTGCTCTTGTAAAAAGAAAA 1128 ATATAAATTTCCTGAAGAATAAAATAGATATATGGCACTTGGAGTGCATCATAGTTCTAC AGTTTGTTT IGFBP3 ADXCRIH.1767.C1_s_at GATGCTATATGATACAACTGTGGCCATGACTGAGGAAAGGAGCTCACGCCCAGAGACTGG SEQ ID GCTGCTCTCCCGGAGGCCAAACCCAAGAAGGTCTGGCAAAGTCAGGCTCAGGGAGACTCT NO: GCCCTGCTGCAGACCTCGGTGTGGACACACGCTGCATAGAGCTCTCCTTGAAAACAGAGG 1130 GGTCTCAAGACATTCTGCCTACCTATTAGCNNNNNNNNNNNNNNNNNNNNNNNNGGGGGG AAAAGTATTTTTGAGAAGTTTGTCTTGCAATGTATTT PDLIM7 ADXCRIH.3383.C1_s_at ATGCACCCAGCTGTGCCAAGTGCAAGAAGAAGATTACAGGCGAGATCATGCACGCCCTGA SEQ ID AGATGACCTGGCACGTGCACTGCTTTACCTGTGCTGCCTGCAAGACGCCCATCCGGAACA NO: GGGCCTTCTACATGGAGGAGGGCGTGCCCTATTGCGAGCGAGACTATGAGAAGATGTTTG 1132 GCACGAAATGCCATGGCTGTGACTTCAAGATCGACGCTGGGGACCGCTTCCTGGAGGCCC TGGGCTTCAGCTGGCATGACACCTG WDR1 ADXCRIH.1007.C1_at CTTTTCTTTTTCAGTGCAGAAATAAAAGTAAATAATAAGCACGGTGATTGGGA SEQ ID NO: 1135 WDR1 ADXCRAD_BU073170_s_at CATTGTCAGATTTTGTGCTTGATTTTAAGAATGGAATTGTGGGTATCTTTCCTTTTTTTT SEQ ID TAATGTATCTTAACTGTTGCCTGTCAGTGTTTACAAACTAGTGCGTTGACGGCACCGTGT NO: CCAAGTTTTTAGAACCCTTGTTAGCCAGACCGAGGTGTCCTGGTCACCGTTTCACCATCA 1136 TGCTTT IL8 ADXCRIH.2782.C1_at CTGTGTTGGCGCAGTGTGGTCCACTCTCAATCACTCTCAGTTCTTTGATAAATTTGGGGT SEQ ID GGAAAGGTTTGGAGTATGTCTTTATGCACTGACATCTAAGTTCTTTAGCACTCCTTGGCA NO: AAACTGCACCTTCACACAGAGCTGCAGAAATCAGGAAGGCTGCCAAGAGAGCCACGGCCA 1141 GCTTGGAAGTCATGTTTACACACAGTGAGATGGTTCCTTCCGGTGGTTTCTTCCTGGCTC TTGTCCTAGAAGCTTGTGTGCTCCTCG VEGFA ADXCRIH.2785.C1_s_at GAACACCGACAAACCCAGCCCTGGCGCTGAGCCTCTCTACCCCAGGTCAGACGGACAGAA SEQ ID AGACAGATCACAGGTACAGGGATGAGGACACCGGCTCTGACCAGGAGTTTGGGGAGCTTC NO: AGGACATTGC 1142 TNFRSF12A ADXCRIH.3000.C1_at CAAAATAAATATCTCCTCCCCGCTTTGGGGAGTTGGGGGGGTCTGTATCTTAGGGCCAGC SEQ ID CCTCCTAGTGGGCCAGCCCCCTAGTGTTAAAAATAGGTCCCTAACCCCCCAGGGTGACCC NO: CCGTGGTGGAATTTCAGGACATCTGAGTGAGTGGGGCCTAGTGTCAAGTCTGCCCCCCAA 1150 GTCAGCCTGGCCCCCAGGGCCTCTAGGAAGGCCTCGTGC LAPTM4B ADXCRIH.1454.C1_s_at TATATTTGATATACTTCTGCCTAACAACATGGAAAAGGGTTTTCTTTTCCCTGCAAGCTA SEQ ID CATCCTACTGCTTTGAACTTCCAAGTATGTCTAGTCACCTTTTAAAATGTAAACATTTTC NO: AGAAAAATGAGGATTGCCTTCCTTGT 1153 PEA15 ADXCRAD_CX867144_s_at GTGTTTTCCTTTGCACCGATCCCCACCCCAATTCAATCCCGGAAGGGACTTACTTAGGAA SEQ ID ACCCTTCTTTACTAGATATCCTGGCCCCCTGGGCTTGTGAACACCTCCTAGCCACATCAC NO: TACAGTACAGTGAGTGACCCCAGCCTCCTGCCTACCCCAAGATGCCCCTCCCCACCCTGA 1154 CCGTGCTAACTGTGTGTACATATATATTCTACATATATGTATATTAAAACTGCACTGCCA TGTCTGCCCTTT JAK1 ADXCRIH.1478.C1_s_at TTTTCAGTTTGCTTGGAGGTAGCTGGGTAATCAAAAATGTTTAGTCATTGATTCAATGTG SEQ ID AACGATTACGGTCTTTATGACCAAGAGTCTTAAAATCTTTTTGTTATGCTGTTTAGTATT NO: CGTTTGATATTGTTACTTTTCACCTGTTGAGCCCAAATTCAGGATTGGTTCAGTGGCAGC 1156 AATGAAGTTGCCATTTAAATTTGTTCATAGCCTACATCACCAAGGTCTCTGTGTCAAACC TGTGGCCACTCTATATGCACTTTGTTTA CNN3 ADXCRIH.2427.C1_s_at GCATTTGTGATTATATGTGTACTCATTCTCTTACCTAGCGAACAAGATCTTTTCAAAGTG SEQ ID GTGTTTCTAAAAGAGCATGTACAAAAGTGGCCTGTGGACATTTAGGCCTGGGTGATGCAT NO: TTGCTCTTCCTGTTTGTGCCAATGTATCAATGTAAAGTTGCTCTGTTTTCTTCAACTGTA 1157 TTTATTGCTGCATTTCTCAGCATAAACTTATCCCATTGT VIM ADXCRIH.436.C1_at TATTCTGAATCTCATCCTGCAGGCGGCCAATAGTGTCTTGGTAGTTAGCAGCTTCAACGG SEQ ID CAAAGTTCTCTTCCATTTCACGCATCTGGCGTTCCAGGGACTCATTGGTTCCTTTAAGGG NO: CATCCACTTCACAGGTGAGGGACTGCACCTGTCTCCGGTACTCAGTGGACTCCTGCTTTG 1159 CCTGGCGCAGGGCGTCATTGTTCCGGTTGGCAGCCTCAGAGAGTCAGCAAACTTGGATTT CCTCTTCGTGGAGTTTCTTCAAAAGGCAATCTCTTCTTGCAAAGAT COL4A1 ADXCRIH.2482.C1_s_at ATAAAGCTTACATAGTTTTCTTCCTTTGAAAGACTGTGCTGTCCTTTAACATAGGTTTTT SEQ ID AAAGACTAGGATATTGAATGTGAAACATCCGTTTTCATTGTTCACTTCTAAACCAAAAAT NO: TATGTGTTGCCAAAACCAAACCCAGGTTCATGAATATGGTGTCTATTATAGTGAAACATG 1160 TACTTTGAGCTTATTGTTTTTATTCTGTATTAAATATTTTCAGGGTTTTAAACACTAATC ACAAACTGAATGACTTGACTTCAAAAGCAACAACCTTAAA NPC2 ADXCRIH.1839.C1_s_at AGTCTGCTGAGACTCTTGACAGCACCTCCAGCTCTGCTGCTTCAACAACAGTGACTTGCT SEQ ID CTCCAATGGTATCCAGTGATTCGTTGAAGAGGAGGTGCTCTGTAGCAGAAACTGAGCTCC NO: GGGTGGCTGGTTCTCAGTGGTTGTCTCATGTCTCTTTTTCTGTCTTAGGTGGTTTCATTA 1163 AATGCAGCACTTGGT OPTN ADXCRIH.2853.C1_at GACCAGCTCAGGACCCAGGTGGTGAGGCTACAAGCAGAGAAGGCAGACCTGTTGGGCATC SEQ ID GTGTCTGAACTGCAGCTCAAGCTGAACTCCAGCGGCTCCTCAGAAGATTCCTTTGTTGAA NO: ATTAGGATGGCTGAAGGAGAAGCAGAAGGGTCAGTAAAAGAAATCAAGCATAGTCCTGGG 1174 GCCCACGAGAACAGTCTCCACTGGCACGGCATTGTCTAAATATAGGAGCAGATCTGCAGA TGGGGCCCAGAATTACTTCGAACATGAGGAGTTAACTG PLAUR ADXCRIH.1121.C1_at GGTAAGGCTGGTGATCTTCAAGCCAGTCCGATAGCTCAGGGTCCTGTTGGTCTTCTCTGA SEQ ID GTGGGTACAGCTTTTCTCCACCAGCTCCAGCTCTTCTCCTTCTTCCCACAAGCGCACGAT NO: CGTGGTCCTGCAGAGGTCCTGTCCCAGGGCGCACTCTTCCACACGGCAATCCCCGTTGGT 1175 CTTACACTGCATGCACCGCA SVIL ADXCRIH.3823.C1_at GGCATTGCCTAGCTGGAACAAGAAGGCAGTGCTATCTATAGCAGCTGCGGCTTAAGTGCA SEQ ID CATAACAGATACTTTTATTAATTCTGATAACCTCCTGAATGGTGGAAAGAAGTTTCCAAA NO: CAGTTCCCTTGAACATTTACAAAATACACAACTCCGGGACAGCAGTATCTTTAACAATGT 1176 CATGTTCTGAAAACTCTGAT PRSS23 ADXCRIH.833.C1_at CCAGATTTGCTATTGGATTAAAGGAAACTACCTGGATTGTAGGGAGGGGTGACACAGTGT SEQ ID TCCCTCCTGGCAGCAATTAAGGGTCTTCATGTTCTTATTTTAGGAGAGGCCAAATTGTTT NO: TTTGTCATTGGCGTGCACACNNNNNNNNNNNNNNNNNNNNNNNNNNAAGGTGTCTTATAA 1177 TCTTTTACCTATTTCTTACAATTGCAAGATGACTGGCTTTACTATTTGAAAACTGGTTTG TGTATCATATCATATATCATTTTAGCAGTTTGAAGGCATACTTTTGCAT C190rf10 ADXCRIH.3832.C1_s_at AGAGAACAGAGGGTCCAGGGCCCTCCTGGCTCCCAACAGCTTCTCAGTTCCCACTTCCTG SEQ ID CTGAGCTCTTCTGGACTCATGATCGCAGATCCGGGGCACAAAGAGGGTGGGGAACATGGG NO: GGCTATGCTGGGGAAAGCAGCCATGCTCCCCCGACCTCCAGCCGAGCATCCTTCATGAGC 1178 CTGCAGAACTGCTTTCCTATGTTTACCCAGGG GATA6 ADXCRIH.2898.C1_s_at AAGTCACGTCCTCCGTGCGACCGGATTCCTGGTGCGCCCTGGCCCTGGCCTGAGCCCACG SEQ ID CCGCCAGGAGGCAGGGAGGGCTCCGCCGCGGGCCTCACTCCACTCGTGTCTGCTTTTGTG NO: CAGCAGTCCAGACAGTGGCGACTGCGCTGACAGAACGTGATTCTCGTGCCTTTATTTTGA 1180 AAGAGATGTTTTTCCCAAGAGGCTTGCTGAAAGAGTGAGAGAAGATGGAAGGGAAGGGCC AGTGCAACTGGGCGCTTGGGCCACTCCA LGALS1 ADXCRIH.2899.C1_at GAAAGACAGCCTCCCGCTGCTCGGTCCCCCAGGCCCCGCCGTCCTTGCTGTTGCACACGA SEQ ID TGGTGTTGGCGTCGCCGTGGGCGTTGAAGCGAGGGTTGAAGTGCAGGCACAGGTTGTTGC NO: TGTCTTTGCCCAGGTTCAGCACGAAGCTCTTAGCGTCAGGAGCCACCTCGCCTCGCACTC 1181 GAAGGCACTCTCCAGGTTTGAGATTCAGGTTGCTGGCGACCAGACCACAAGCCATGATT PTPRK ADXCRIH.91.C1_at TATAATGTGCTTTCTCCATATAGACATATTTACACTTGAGTCTTTGGCTTATGTTATTTT SEQ ID CTAAAAAGAACTTTAAATGATCCAGCCATCATTGCACATTAAAAGAAAATAAGCCAGTTA NO: TATATATTTATATATTCCCATAGAGATCTGCTACACTGGAAACATATAAAAAACGAACTT 1182 TACTATGAATTTGCACAGCTTTTCTTTTCTTCTTCCTTTTAAGATTCATCAGCTTTCATT TTAGAAAGGGAGCCTCGTGC SLC39A7 ADXCRIH.2110.C1_at AGGGTTAGTTGGTATTCTCATGGCCTGATTTTTTTTGTTTCTATTCCTTTTATATCACTG SEQ ID TGTTTGAATCGAGGGGGAGGGGTGGTAACCGGAAATAAAGATCTCCGATCTTCCGCC NO: 1185 SLC39A7 ADXCRAD_BM796805_s_at ATAGTGTTGGGCACTGTCTGACCATGTTGCATTTGGAAGGCTAAATGGGGCCATGAAGAA SEQ ID GGCTGGAAGGGACAGGTGGTGATGGCAGCCTACCTGGTGTCCCCTACCCCACCTGTTCTC NO: GGAGAACCAAGTTGCTACACAGGAAGTTCTCCAAGGTCCAGTTTCCTTTCTCCCACCAGT 1186 TGGTGGAGGCTTCAGGGAAGACCAGAGTCCTGNACAGAGAGGGTAACAGGAGGAGTCGGG GATAAACATCAAACATCAATCGTGTGTCCTGATTTGGGAGTGAT RRAS ADXCRIH.3859.C1_at GAGGCCTCAAAGTAGGCCACGTGGTGGGAGGCGCCGAAGGCAGAGGCTTCTGATCGGGGG SEQ ID ACCTGGCGCTGTGACTCCAGATCTGCCTTGTTCCCGACCAACACAACGGGGAAGTCGTCG NO: CGGTCCTTGACCCGCAGAATCTGCGTGAAGAGCTTGCCCACCTCGTTGAAACTCTGCCGG 1188 TCATTAATGGCGAACACCAGCAGGAAACCGTGGCCAGCACGCATGTACTGCTCTCTCATG GCCCCGAACTCTTCCTGGCCCGCGGTGTCCAGGGATGTCCAGC PLAU ADXCRIH.107.C1_at TCACTGGGTGGGGTGAGGACCACTCCTTACACTG SEQ ID NO: 1192 PLAU ADXCRIH.107.C1_s_at TAAGTGTGAGTAAGAGCTGGTGTCTGATTGTTAAGTCTAAATATTTCCTTAAACTGTGTG SEQ ID GACTGTGATGCCACACAGAGTGGTCTTTCTGGAGAGGTTATAGGTCACTCCTGGGGCCTC NO: TTGGGTCCCCCACGTGACAGTGCCTGGGAATGTATTATTCTGCAGCATGACCTGTGACCA 1193 GCACTGTCTCAGTTTCACTTTCACATAGATGTCCCTTTCTTGGCCAGTTATCCCTTCCTT TTAGCCTAGTTCATCCAATCCTCACTGGGTGGG MXRA7 ADXCRIH.2503.C1_at ATGGCAACAGCCACACAGTCATTGCCTTCAACACAGAGCCACGTGTCCCCAAACAGCAAT SEQ ID AGTCATGCCCTTGTCCAGGCTGGGATCTAATTGATACAATAGGTCGTTGACTCCCTCCTA NO: GTAGAGCTATCTAGGTTTGTCTGGAAAGTTTCCGACCCTGGCTTATAGGCACCACACCTC 1205 ATGTACTCCTCATGGCTTGGATCTCTGTATTCAGCCTTTGTTCAGTCC CYR61 ADXCRIH.1579.C1_at TACCTAATATCTGAGTGTATGCCATTCGGTATTTTTAGAGGTGCTCCAAAGTCATTAGGA SEQ ID ACAACCTAGCTCACGTACTCAATTATTCAAACAGGACTTATTGGGATACAGCAGTGAATT NO: AAGCTATTAAAATAAGATAATGATTGCTTTTATACCTTCAGTAGAGAAAAGTCTTTGCAT 1207 ATAAAGTAATGTTTAAAAAACATGTATTGAACACGACATTGTATGAAGCACAA HSBP1 ADXCRIH.524.C1_at CCCTTCAATTATAGTTAGTCTTGGTGAAGTAAGATGTTTGTAGACTTTAGAGTTCTTTAA SEQ ID TTCTTGGCACAACGTGACTGTTGAGCTAACACCAAATAGTGTGTTGGCAATACTTTTCAA NO: ATGGCTGAAAACACCTAAAAATTGTTCATTCCGAAATATCTGTCACTGCTCTGTTGCCAA 1211 ACTCAGAATAGAACTTAGACGTATGTCTGAGTCCCTGAGATCACATGCTAAAGTCGATGA AAGTAACCACTGCCACTGTCTGTGTCAGAACTTTACAGTACAG CALU ADXCRAD_CX788634_s_at ATGTCATTGAAAGTGCCTTTAACGAAAGAAATGGTCACTGAATGGGAATTCTCTTAAGAA SEQ ID ACCCTGAGATTAAAAAAAGACTATTTGGATAACTTATAGGAAAGCCTAGAACCTCCCAGT NO: AGAGTGGGGATTTTTTTCTTCTTCCCTTTCTCTTTTGGACAATAGTTAAATTAGCAGTAT 1218 TAGTTATGAGTTTGGTTGCAGTGTTCTTATCTTGTGGGCTGATTTCCAAAACCACATGCT GCTGAATTTACCAGGGATCCTCATACCTCACAATGCAAACCACTTACTACCAG CTSA ADXCRIH.551.C1_at AAAGTGCCCCTGCAGGCCGGGTTCTGCCGCCAGGACTGCCCCCTTCCCAGAGCCCTGTAC SEQ ID ATCCCAGACTGGGCCCAGGGTCTCCCATAGACAGCCTGGGGGCAAGTTAGCACTTTATTC NO: CCGCAGCAGTTCCTGAATGGGGTGGCCTGGCCCCTTCTCTGCTTAAAGAATGCCCTTTAT 1219 GATGCACTGATTCCATCCCAGGAACCCAACAGAGCTCAGGACAGCCCACAGGGAGGTGGT GGACGGACTGTAATTGATAGAT ALCAM ADXCRIH.556.C1_s_at TAAAACAGAATTTGGTAGCACTTACCTCTACAGACACCTGCTAATAAATTATTTTCTGTC SEQ ID AAAAGAAAAACACAGCATGTGTGAGAGACAGTTTGGAAAAATCATGGTCAACATTCCCAT NO: TTTCATAGATCACAATGTAAATCACTATAATACAAATTGGTGTTAAATCCTTTGGGTTAT 1220 CCACTGCCTTAA KDELR3 ADXCRIH.3560.C1_at GTATGTGACCAAAGTCCTTAAGGGAAAGAAGTTAAGTCTTCCAATGCCAATCTGAGGACC SEQ ID TTCAGAGACAGTCTACGCCTTAACAAGCACATGAAGGAAACTATTTTGAATGTTCTCTTT NO: GGCAACTTATCCATAATTTGGGATCAAATGTTAAAACCAGAAAAGTGTTTAGTGTGGATT 1221 TCAGCAAACCTG TIMP1 ADXCRIH.2934.C1_s_at TGCAAACTGCAGAGTGGCACTCATTGCTTGTGGA SEQ ID NO: 1226 TAGLN2 ADXCRIH.1215.C1_at TGGCCTTGCTTCTACAAGTATGCTTCTCCCACAGCTGTGGCTGCAGGAACTTAATTTATA SEQ ID GGGAGGAGCCTGTGGCAGCTGCTGCCCCAGCCACAGCTGCACTGACTGTGCTCACCACAC NO: ATCTGGGGCAGCCTTCCCTGGCAGGGGCCCTCGTGGCTTCTCATTTTCCATT 1230 TAGLN ADXCRIH.1215.C1_x_at TGGCCTTGCTTCTACAAGTATGCTTCTCCCACAGCTGTGGCTGCAGGAACTTAATTTATA SEQ ID GGGAGGAGCCTGTGGCAGCTGCTGCCCCAGCCACAGCTGCACTGACTGTGCTCACCACAC NO: ATCTGGGGCAGCCTTCCCTGGCAGGGGCCCTCGTGGCTTCTCATTTTCCATTCCCTTCAC 1231 TGTGGCTAAGGGGTGGGGTGAGGGGATGGAGAGGGAGGGCTGCCTACCATGGTC COL4A2 ADXCRIH.1229.C1_at ACTGCCCCACGTTGTCCCTGAGATTTAACCCCTCCACTGCTGGGGGTGAGCTGTACTCTT SEQ ID CTGACTGCCCCCTCCTGT NO: 1234 COL4A2 ADXCRAD_BM700172_s_at GGCCCTGCTTTCTACGCCAATGTTATGCCAGCTCCATGTTCTCCCAAATACCGTTGATGT SEQ ID GAATTATTTTAAAGGCAAAACTGTGCTCTTTATTTTAAAAAACACTGATAATCACACTGC NO: GGTAGGTCATTCTTTTGCCACATCCCTATAGACCACTGGGTTTGGCAAAACTCAGGCAGA 1235 AGTGGAGACCTTTCTAGACATCATTGTCAGCCTTGCTACTTGAAGGTACACCCCATAGGG TCGGAGGTGCTGT COL5A2 ADXCRIH.2984.C1_s_at AATTCGGCGTTGAAATTGGGCCAGTTTGTTTTGTGTAAAGTAAGCCAAGACACATCGACA SEQ ID ATGAGCACCACCATCAATGACCACCGCCATTCACAAGAACTTTGACTGTTTGAAGTTGAT NO: CCTGAGACTCTTGAAGTAATGGCTGATCCTGCATCAGCATTGTATATATGGTCTT 1239 PRNP ADXCRIH.1264.C1_s_at CATAGGACAGACTTAGGAGTTTTGTTTAGAGCAGTTAACATCTGAAGTGTCTAATGCATT SEQ ID AACTTTTGTAAGGTACTGAATACTTAATATGTGGGAAACCCTTTTGCGTGGTCCTTAGGC NO: TTACAATGTGCACTGAATCGTTTCATGTAAGAATCCAAAGTGGACACCATTAACAGGTCT 1241 TTGAAATATGCATGTACTTTATATTTTCTATATTTGTAACTTTGCATGTTCTTGTTTTG TMBIM1 ADXCRIH.1270.C1_at GGAGAAGACACATCTTCAGCCTAGTCCCTGCCAAGCCCACCAAGAGCAACAGTTAGTCCC SEQ ID TAGCTCCTCCGTCCCCACCAAGTACCCACACATCCATAGCCAGAGAGGCCACCTGTCTCC NO: AGGACAGAAAGGAAACTGGGCATGTTACTCAAGGGGAAGGAAAGGGGCCTAAAGCCCAGA 1243 CCACAGTCATAGGGCCCAGCCCTCTAGCTTGGAAGGGAGAGCCCAGGATCGGGTGAAAAT GGGGGCTTGCTCCTTAATTGCGATCCC ACTN4 ADXCRIH.2218.C1_at AGAGCAGGAGAGACGGCAGAGATATGTTGCTAGGTGAATATATATTTATATAATAAATCC SEQ ID GTAAGTTAATAAAGTAAATAGTAATTCTCTG NO: 1244 ACTN4 ADXCRIH.2218.C1_s_at ACCATCAACCACCAGGCAGCCAGGCCATCAGCCCACCTCCACCTCTGGAGGGTCCCCAGA SEQ ID GACCCACGCCCGACGCAGACCCGGAGGAGCATCAGCAAGGGGCCCGGGCAGAGAATCGGC NO: TATGTCTTCATTATGAGA 1245 CASK ADXCRIH.3207.C1_s_at GTATCTCATGACCAAATGATGCAAGACATCTCTAATAACGAGTACTTGGAGTACGGCAGC SEQ ID CACGAGGATGCGATGTATGGGACAAAACTGGAGACCATCCGGAAGATCCACGAGCAGGGG NO: CTGATTGCAATACTGGACGTGGAGCCTCAGGCACTGAAGGTCCTGAGAACTGCAGAGTTT 1248 GCTCCTTTTGTTGTTTTCATTGCTGCACCAACTATTACTCCAGGTTTAAATGAGGATGAA TCTCTTCAGCGTCTGCAGAA KCMF1 ADXCRIH.1604.C1_s_at GGTGATTGTAATTTCAGGTCTGTCACTCTTGTTACATTGTGTACATTCAAAAGGAAGAGA SEQ ID GAAAATATATATGATAATCATTTCCACTTAACTAATTTTTACTTCTAGCAGGTAAATGTA NO: GGTAGCAGTGCAGGGGTGATCTCTGCTTCCTGTACCTTGACATGCAAAAGGCTCTCCTAA 1249 TACTCCACATTCAAACTGAAGAGGAAAATTGAAATCTCTAATGAAGCTGCTGTGTGTATT TATGAATATTAATGAATAAAAACTGCTTGGATGGT YES1 ADXCRIH.3214.C1_at GGCAGGAAAGTTGATGGGATTCATTAGGTTTACTGGATGGAGCAGTTCCCTATATAATAC SEQ ID CAATGGAATAGTAAGGGATAAAACCTACATGTGTATTCTT NO: 1250 YES1 ADXCRAD_CX784933_s_at GCAAGTTGGCAGTGGTTCTGGTACTAAAAATTGTGGTTGTTTTTTCTGTTTACGTAACCT SEQ ID GCTTAGTATTGACACTCTCTACCAAGAGGGTCTTCCTAAGAAGAGTGCTGTCATTATTTC NO: CTCTTATCAACAACTTGTGACATGAGATTTTT 1251 MAP1LC3B ADXCRIH.2287.C1_at AGTGGTGTAATTGTGATTTTCCTGTGATACTCCCAAGAAAACTATAAATAGTGAACCCCA SEQ ID TGCAAGTACTGGGAAGCACTAGTCTTTTATCACAGGTTGAACCTGAGGAGGTTTAACTCT NO: TGACATTAGTATCTGTAAAAGAGCGTACGGCTCTTTTTGCTATGTTTTCTCCACAACTGA 1255 CATGCACTTGGTGTGGGAGAATTCCGATGGCTGTCTGACCTAAGAGTGATACTACTATTC AAAATGTGGGTACCTTTTCAGTAATACTGA SCRN1 ADXCRIH.243.C1_at ATAATCGAAATTATGGAGGTTCCTTAGTGCTCAATAATATAAGACCTGTTGTTATTAGAA SEQ ID CGAGTCTTTCTTATAAACTAACAGAGCAGGTATATGCCTGTTAGATCTTAGCTGTGGGGT NO: TCCTTTACTATTGGGTGAATCATTAGGTATAAAAAATAATCATCAACCAGGCCAAATACT 1256 TTGCTTCCTAGCTGATGTCATCCCACATTGGTACAGTGTTATTCATTACTGGGTGGTTCA ACAGGGAAGCCAGTGGGA SCRN1 ADXCRIH.243.C1_s_at GGTTCCTTTACTATTGGGTGAATCATTAGGTATAAAAAATAATCATCAACCAGGCCAAAT SEQ ID ACTTTGCTTCCTAGCTGATGTCATCCCACATTGGTACAGTGTTATTCATTACTGGGTGGT NO: TCAACAGGGAAGCCAGTGGGACCAGTGTGTCTGTCATGAAAC 1257 SEPT7 ADXCRIH.335.C3_s_at TTACACTTTATGGTAAGTAGCAGGGGGGGAAATGCATTTATAGATCATTTCTAGGCAAAA SEQ ID TTGTGAAGCTAATGACCAACCTGTTTCTACCTATATGCAGTCTCTTTATTTTACTAGAAA NO: TGGGAATCATGGCCTCTTGAAGAGAAAAAAGTCACCATTCTGCATTTAGCTGTAT 1260 YWHAZ ADXCRAD_CV571569_s_at TTCTGTCTTGTCACCAACCATTCTTACTTGGTGGCCATGTACTTGGAAAAAGGCCGCATG SEQ ID ATCTTTCTGGCTCCACTCAGTGTCTAAGGCACCCTGCTTCCTTTGCTTGCATCCCACAGA NO: CTATTTCCCTCATCCTATTTACTGCAGCAAATCTCTCCTTAGTTGATGAGACTGTGTTTA 1264 TCTCCCTT YWHAZ ADXCRIH.776.C2_x_at AAATATTTCCTCAGTACTTTGCAGAAAACACCAAACAAAAATGCCATTTTAAAAAAGGTG SEQ ID TATTTTTTCTTTTAGAATGTAAGCTCCTCAAGAGCAGGGACAATGTTTTCTGTATGTTCT NO: ATTGTGCCTAGTACACTGTAAATGCTCAATAAATATTGATGATGGGAGGCAGTGAGTCTT 1265 GATGATAAGGGTGAGAAACTGAAATCCCAAACACTGTTTTGTTGCTTGTTTTATTATGAC CTCAGATTAAATTGGGAAATATTGGCCCTTTTGAATAATTGCCTCGTGC RCN1 ADXCRIH.419.C1_s_at ATACAATGCATTTCCTCAGTGATCACTGATTAGAATGAGTTGGTGGGATCCTTGGGAAGC SEQ ID CAAACGGAGCGGAGTTCTGGATCATGTCCCATCCAGTCCAGTGAATCCACGACCCGCAGA NO: CCTGCCCCCCCGCAACAGCTTATACCATGGAATGAGGACAAGGTGATACTCTGAGCTGTG 1269 GACTGAACTGGCAGACACAACCTGTACAGATTGAAATTTCACCTTGTAA ZFP36L1 ADXCRIH.786.C2_at TCTCAAGACATTCCACTCACAGATTTGAGGTTCTGGATTCCAGGTCTGGAGTTTTCCCAT SEQ ID GTTAATGTAAACAGAACTGGCACACACACATTAAAGATGAATGTAATTATTATTCCTCTT NO: GCTGGTCACTACCGTCGCTTTCTATTTCTCTTTCTTTGTGTGAATTTATTTNNNNNNNNN 1270 NNNNNNNCCTTTTGTAACGACTATTTGCAGTTTAAAATC ZFP36L1 ADXCRIH.786.C2_x_at GAGAAACCCTTTGACTTCCACGTGCCCATCTCAAGACATTCCACTCACAGATTTGAGGTT SEQ ID CTGGATTCCAGGTCTGGAGTTTTCCCATGTTAATGTAAACAGAACTGGCACACACACATT NO: AAAGATGAATGTAATTATTATTCCTCTTGCTGGTCACTACCGTCGCTTTCTATTTCTCTT 1271 TCTTTGTGTGAATTTATTTNNNNNNNNNNNNNNNNCCTTTTGTAACGACTATTTGCAGTT CAV1 ADXCRIH.1095.C2_at TTTATTCCTCCTGCTCATATTGTGATTCTGCCTTTGGGGACTTTTCTTAAACCTTCAGTT SEQ ID ATGANNNNNNNNNCATACACTTATTGGAACTCTGCTTGATTTTTGCCTCTTCCAGTCTTC NO: CTGACACTTTAATTACCAACCTGTTACCTACTTTGACTTTTTGCATTTAAAACAGACACT 1272 GGCATGGATATAGTTTTACTTTTAAACTGTGTACATAACTGAAAATGTGCTATACTGCAT ACTTTTTAA PRSS23 ADXCRIH.795.C1_at GGATCAGAATCATGCCTTCCAATAAAGGCCTTTACACATGTTTTATCAATATGATTATCA SEQ ID AATCACAGCATATACAGAAAAGACTTGGACTTATTGTATGTTTTTATTTTATGGCTCTCG NO: GCCTAAGCACTTCTTTCTAAATGTATCGGAGAAAAAATCAAATGGACTACAAGCACGTGT 1275 TTGCTGTGCTTGCACCTCAGTAAACCTGCATTGTAGCAATTTGTAAGGATATTCAGATGG AGCACTGTCACTTAACATTCTCTGGG ANXA2 ADXCRIH.511.C2_s_at TAGAAAACCAGCTTGCGAATAACAGTCCCCGTGGCCATCCCTGTGAGGGTGACGTTAGC SEQ ID NO: 1276 GJA1 ADXCRIH.1842.C1_at GTGATGGTAATGATATTGTGCAAGTGGATGGAAAAAGAATATACGTATTTGCAAATGCAT SEQ ID GGAAAATCTTATTCTGTGGGCCTTGTCTGAATTTTAAACTGATACCAAGAATAAAAAAAT NO: ATAGTAGCACAAGTCCATTGACACCTGGAGGGTCAGGCCTAGAAAGCTTACCTTCAAAGT 1277 GCAAATTTTAACAATGGAATGTTTTAGCAGGGACTTAAGCCTCGTGC SLC20A1 ADXCRIH.3036.C2_s_at CAGTAGTGGCAGGATCTATTGGCATATTCGGGAGCTTCTTAGAGGGATGAGGTTCTTTGA SEQ ID ACACAGTGAAAATTTAAATTAGTAACTTTTTTGCAAGCAGTTTATTGACTGTTATTGCTA NO: AGAAGAAGTAAGAAAGAAAAAGCCTGTTGGCAATCTTGGTTATTTCTTTAAGATTTCTGG 1282 CAGTGTGGGATGGATGAATGAAGTGGAATGTGAACTTTGGGCAAGTTAAATGGGACAGCC TTCCATGTTCATTTGTCTACCTCTTAACTGAATAAAA JUN ADXCRIH.716.C2_at GATGAAAAGCTGATTACTGTTCAATAAACAGCTTCCTGCCTTT SEQ ID NO: 1287 JUN ADXCRIH.716.C2_s_at CAAACTGCAATAGAGACTGTAGATTGCTTCTGTAGTACTCCTTAAGAACACAAAGCGGGG SEQ ID GGAGGGTTGGGGAGGGGCGGCAGGAGGGAGGTTTGTGAGAGCGAGGCTGAGCCTACAGAT NO: GAACTCTTTCTGGCCTGCCTTCGTTAACTGTGTATGT 1288 DNAJB1 ADXCRIH.815.C2_s_at TGGGGCTTACCAGTGGCCCAGGTAATTTTTTGTTTCATGGACTATGGACTCTTTCAAAGG SEQ ID GATCTGATCCTTTTGAATTTTGCACAGCCCTAGATACAATCCCTTTTGATAAAAGGGTCT NO: TTGCTTCTGATTACAGGAGCACTGTGGAACGTCTGTAAATATGTTTTTATATTTCCATGT 1290 ATAGTTGGTGTACACTCAAAACCTGTCC S100A10 ADXCRIH.249.C2_at GGCAGAAATGAGCAGTTCGCTCCTCCCTGATAAGAGTTGTCCCAAAGGGTCGCTTAAGGA SEQ ID ATCTGCCCCACAGCTTCCCCCATAGAAGGATTTCATGAGCAGATCAGGACACTTAGCAAA NO: TGTAAAAATAAAATCTAACTCTCATTTGACAAGCAGAGAAAGAAAAGTTAAATACCAGAT 1295 AAGCTTTTGATTTTTGTATTGTTTGCATCCCCTTGCCCT SPTBN1 ADXCRIH.820.C2_at CTGTACCTCTCAACTTTTGCCCTATCTGTTAAATATATGCTAT SEQ ID NO: 1296 SPTBN1 ADXCRIH.820.C2_s_at GTTACTCTAATGGTTACTTGCTCGTGCGTTGCCACACTGTGTTATAATTTGCTTCATTTC SEQ ID CTTGCTATTTGATACATAGTGTGCATTTCTCTGTCACTGTAACTATTGTAATGACAAATT NO: TTCATCTTACTGCACAATCAAAATGACATTGATAGGAATGAACTCCAGAGGCTGGGCCTG 1297 AACAGGGAGGTGGTCGCTCAGGCCTGGTGCTCAGTCGTACGACCTGTACCTCTCAA MARCKS ADXCRIHRC.653.C1_at TTTTTGATCCATTATTCCAATTAAGAATGCGTGTCAAAACCTAATTTGTTATTTTTCTAA SEQ ID TGAGTTTAAGATTTGGCATTCAGTTGTTACACATGTGGTTCAATGATTTATCATGAACCC NO: TAAACTGCACACTGCTCAAAAACAGCAAAACAGATGTGCATTAAATGAAATAATGTTTTT 1305 GATACATATCTTAAATTTCAATCAGTTTAGGGTCCTTTGAAGGAAAAGATATCCAGTTAT CGGGTGGCAAAGAGCAGAGGAGGTAAACTCCTCGTGCCG IL8 ADXCRIHRC.2782.C1_s_at AACAATCCTAGTTTGATACTCCCAGTCTTGTCATTGCCAGCTGTGTTGGTAGTGCTGTGT SEQ ID TGAATTACGGAATAATGAGTTAGAACTATTAAAACAGCCAAAACTCCACAGTCAATATTA NO: GTAATTTCTTGCTGGTTGAAACTTGTTTATTATGTACAAATAGATTCTTATAATATTATT 1310 TAAATGACTGCATTTTTAAATACAAGGCTTTATATTTTTAACTTTAAGATGTTTTTATGT GCTCTCCAAATTTTTTTTACTGTTTCTGATTGTATGGAAAT TNFRSF12A ADXCRIHRC.3000.C1_s_at SEQ ID ACTTGGGGGGCAGACTTGACACTAGGCCCCACTCACTCAGATGTCCTGAAATTCCACCAC NO: GGGGGTCACCCTGGGGGGTTAGGGACCTATTTTTAACACTAGGGGGCTGGCCCACTAGGA GGGCTGGCCCTAAGATACAGACCCCCCCAACTCCCCAAAGCGGGGAGGAGATATTTATTT 1311 TG VIM ADXCRAD_CX873552_s_at AAGCAGGAGTCCACTGAGTACCGGAGACAGGTGCAGTCCCTCACCTGTGAAGTGGATGCC SEQ ID CTTAAAGGAACCAATGAGTCCCTGGAACGCCAGATGCGTGAAATGGAAGAGAACTTTGCC NO: GTTGAAGCTGCTAACTACCAAGACACTATTGGCCGCCTGCAGGATGAGATTCAGAATATG 1312 AAGGAGGAAATGGCTCGTCACCTTCGTGAATACCAAGACCTGCTCAATGTTAAGATGGCC CTTGACATTGAGATTGC SVIL ADXCRIHRC.3823.C1_at ACCGGTTGTAAAAACAGTACACATGTCATTTTGTGATATAGGACTCCCAAATAAAAGTAT SEQ ID CAGAATAAACACCTCGTGC NO: 1314 SVIL ADXCRAD_CN402078_s_at GTATCTTCATACACGTTTGGAAATGTTTCCTGCAGCATTAGGTATGACTTGTTCTGAGTA SEQ ID CTGCTTCCGGTGCTAAAATGAACAAAGAATTTGTACTTAATGGCATGGACTCTGGAGAAT NO: CTATGCGAATCAACCTTTCTACCTTAATATCTCCCCAAAAATGTATAGTGCCTTGTTTTT 1315 ATGTACAGTTTATATACAGAAAAGTTTGCTCTGCATTTTTGATGATGGTTTGGAACATTA TCTACAAT LGALS1 ADXCRIHRC.2899.C1_at AACACCATCGTGTGCAACAGCAAGGACGGCGGGGCCTGGGGGACCGAGCAGCGGGAGGCT SEQ ID GTCTTTCCCTTCCAGCCTGGAAGTGTTGCAGAGGTGTGCATCACCTTCGACCAGGCCAAC NO: CTGACCGTCAAGCTGCCAGATGGATACGAATTCAAGTTCCCCAACCGCCTCAACCTGGAG 1317 GCCATCAACTACATGGCAGCTGACGGTGACTTCAAGATCAAATGTGTGGCCTTTGACTGA AATCAGCCAGCCCATGGC PTPRK ADXCRIHRC.91.C1_s_at CAATGCCAGATTCCTGTTTTGCGCATTGTCATGGGATTCTTAAGTGAACCTTTCTAAATG SEQ ID TGGTCTTGTTCACATGCTCCACGTAGCTGTAACTTCACATCATCAGCTTGCAGTTTGTAA NO: TTGACTAAAGCATTCCAGTGTCCTCTTTCTAGATTGCCAGCTCATGACATGGTGCTTATA 1318 AAGA RRAS ADXCRIHRC.3859.C1_at GAGAGAAGCAACCACCACAAGCTCTCGGGACTAGCTGCCTTCGCACCTTGCTGTGTGACC SEQ ID TGAGGCCCTCACTGAGCCTCAATTTCCTCATCTGGGTCTCCCAGGACACATCACATACCC NO: ACCCTTACTTCCTGGCCTCTTCTGGGCTACTGCCACTGTGTGCCTTCTGCCAACGCCTCC 1319 TGTCCCCACCTAAGCCTGGTGGGGGTGAGGGGCTCCGGGTCACTGCTGTATATAACTCCC CTCCCCCAGAAAAATAAATGTCACTGCCAACGTCCTCGTG ACTN4 ADXCRIHRC.2218.C1_at ATATTCACCTAGCAACATATCTCTGCCGTCTCTCCTGCTCTCATAATGAAGACATAGCCG SEQ ID ATTCTCTGCCCGGGCCCCTTGCTGATGCTCCTCCGGGTCTGCGTCGGGCGTGGGTCTCTG NO: GGGACCCTCCAGAGGTGGAGGTGGGCTGATGGCCTGGCTGCCTGGTGGTTGATGGTTTTG 1326 CCTCGT MAP1LC3B ADXCRIHRC.2287.C1_at ATGTATATTCTTAACTGGACTGTCTTGTTTAGACTGTATACATCATATCCGACATTATTG SEQ ID TAACTACCGTGTGATCAGTAAGATTCCTGTAAGAAATACTGCTTTTTAAGAAAAAAAATA NO: ACATGCTGAGGGGTGACCTATATCCCATGTGAGTGGTCACTTTATTTATAGGATC 1327 YWHAZ ADXCRIHRC.776.C2_at TACATGAATTTAATACACGTGTTCTTAACAATTATGCTTGGATTGTTCATGAAAATTTCA SEQ ID TAAGACATTAAACAAAGCTAGCCATCATCTCAAGTTATTTCCCTGTTAACTATTTTTACA NO: GCACATGCATGTTAGGCAAGTATCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN 1328 NNNNNNNNNGTTAAATACATGGGTTTTTGTTTTACTGCTGTGCTTGATATACATGAAGTA ATGCCTCGTGC YWHAZ ADXCRIHRC.776.C2_x_at AAACTTTTATTCCACTTACATGAATTTAATACACGTGTTCTTAACAATTATGCTTGGATT SEQ ID GTTCATGAAAATTTCATAAGACATTAAACAAAGCTAGCCATCATCTCAAGTTATTTCCCT NO: GTTAACTATTTTTACAGCACATGCATGTTAGGCAAGTATCNNNNNNNNNNNNNNNNNNNN 1329 NNNNNNNNNNNNNNNNNNNNNNNNNGTTAAATACATGGGTTTTTGTTTTACTGCTGTGCT TGATATACATGAAGTAATGCCTCGTGC GJA1 ADXCRIHRC.1842.C1_s_at TGAAGACATCTACCAGTTTCTCCAAATGCCTTTTTTAAAACTCATCACAGAAGATTGGTG SEQ ID AAAATGCTGAGTATGACACTTTTCTTCTTGCATGCATGTCAGCTACATAAACAGTTTTGT NO: ACAATGAAAATTACTAATTTGTTTGACATTCCATGTTAAACTACGGTCATGTTCAGCTTC 1330 ATTGCATGTAATGTAGACCTAGTCCATCAGATCATGTGTTCTGGAGAGTGTTCTTTATTC CAST ADXCRIHRC.622.C3_at AGAAGGCATATTCAGAGTTCTTTTTAAATAAATGTTGTTTACTTTTATAGGCATCTTTAA SEQ ID ACTTCTGGATTTTGGTATGCCATTTAAAAATACTTCCAGATACACATGGAAATTAGTAAT NO: ACTGCAGCCGTATCCTTGCAAACACATCTGTCAGTGTCAAAGGTTTCAAGGTTTTTCTTN 1333 NNNNNNNNNNNNNNNNNNNNNNNCACCTATACTGCCCAAATGGGAGGATTAGATACATGG TTAGAAATCCCTCAGGAAA PPIC RDCR013_A07_at CATTTATGCATATTTCTCTATACTGTCTTTTACATGCACAAGACATTTGAAGTAATATAC SEQ ID TGTAAAACTGTACAATTAAAATTATAAATAAAATGTAAGACCATGACATGAAATCCAAAC NO: AGTACATGGATGAATTATAAGAAGATTAGCTAATCTGCTAGCAGTTATCTTTTGTAATAC 1337 TA PPIC RDCR013_A07_x_at GCCTGGCCCAATTACTTTCATTTATGCATATTTCTCTATACTGTCTTTTACATGCACAAG SEQ ID ACATTTGAAGTAATATACTGTAAAACTGTACAATTAAAATTATAAATAAAATGTAAGACC NO: ATGACATGAAATCCAAACAGTACATGGATGAATTATAAGAAGATTAGCTAATCTGCTAGC 1338 AGTTATCTTTTGTAATACT FNDC3B RDCR250_A04_at ATGGATTAACCTCGTTAACAAGAAGAAAAGGCAATTGTGATTTCTAAAGTGGAAAGGCAG SEQ ID GTAGGTTGCAAAGACTCCCCTACACTGAAAATACGATTCTTTTCCATTCTCAGCTGTAAT NO: TGCTGAAAGCTCAAGTAATAGGCTAAGGTAACATACAAGGCCTAAAACCTTATTCCTTTA 1340 TCATTCAGTACTGAACGTTCCTCTAAGAGACTGCACTTTTTCCCGCCACCTCAAAAACAG CCCTGAATCAAGCCTGGCCTGCCCACTTCAGCAACACTAGCCCAGCTACAG MARCKS RDCR156_A02_at GAAGTGAAATAATCATGCCTGCCCTGGCTGCTTCTGTGAGTGGAAGATCATAATTGGAGT SEQ ID GCATGAAAGACTTTGTAAACTGTTAAGTGCTCTATAAACGTTAGCATTTTACTCAATAAA NO: TTTTTATCACACATTCGATGGAATAAGGAAAGAGAATTGAAATAATACAGTTTTTCTTCA 1347 TTGCCTTAGATTATAATTCAGATATAATACAGTTCATTACATTTCATAGTTGTGGCTATT TCAGTAAAT MARCKS RDCR156_A02_x_at AGTGAAATAATCATGCCTGCCCTGGCTGCTTCTGTGAGTGGAAGATCATAATTGGAGTGC SEQ ID ATGAAAGACTTTGTAAACTGTTAAGTGCTCTATAAACGTTAGCATTTTACTCAATAAATT NO: TTTATCACACATTCGATGGAATAAGGAAAGAGAATTGAAATAATACAGTTTTTCTTCATT 1348 GCCTTAGATTATAATTCAGATATAATACAGTTCATTACATTTCATAGTTGTGGCTATTTC AGTAAAT MAPK1 RDCR077_G03_at GTATGTTCAAATAAGCTTTCAGACTAATAGCTTTTTTGGTGTCTAAAATGTAAGCAAAAA SEQ ID TTCCTGCTGAAACATTCTAGTCCTTTCATTTAGTATAAAGA NO: 1349 MAPK1 ADXCRPD.11685.C1_s_at ATTCCCCTTCCTGGTACTGTGGAGTCAGATTGGCATGAAACCACTAACTTCATTCTAGAA SEQ ID TCATTGTAGCCATAAGTTGTGTGCTTTTTATTAATCATGCCTAAACATAATGTAACTGGG NO: CAGAGAATGGTCCTAACCATAGGTACCTATGAAAAGCGCTAGCTATCATGTGTAGTAGAT 1350 GCATCATTGTGGCTCTTCTTACATTTGTAAAAATGTACAGATTAGGTCATCTTAATTCAT ATTA COL5A2 RDCR149_E06_at AAAGGGCAAGCAATAGATTTTTCATGACTGAATAAACTGTAATAATAAAACATATGTCTC SEQ ID AAAGTGTATCACATATGAATTTAGCCTAATTGTTTTCAGTTTCATTCTCAATATTTAGTT NO: TACAACATCATTTTCCCCTAAACTGGTTATATTTTGACCTGTATATCTTAAATTTGAGTA 1356 TTTATATGCCTAAATACATGTGTGAGTTTTGTTTGACTTCCAAGTCCAAACTATAG COL5A2 RDCR149_E06_x_at TGCCCTTAAAAATGTCAGAGTAGTATTATTGATAAAAAGGGCAAGCAATAGATTTTTCAT SEQ ID GACTGAATAAACTGTAATAATAAAACATATGTCTCAAAGTGTATCACATATGAATTTAGC NO: CTAATTGTTTTCAGTTTCATTCTCAATATTTAGTTTACAACATCATTTTCCCCTAAACTG 1357 GTTATATTTTGACCTGTATATCTTAAATTTGAGTATTTATATGCCTAAATACATGTGTGA GTTTTGTTTGACTTCCAAGTCCAAACTATA CAV2 RDCR300_A12_at GGTTCGGCATTCATGTGTATTCCATTCNNNNNNNNNCTCTGTACTTTCTTTTCATACATT SEQ ID TCTTGTCTCTGCAATGAGGCTGAGCGAGACTGTCCCAAATGTGTTTTTATCCTGAGTCTG NO: AGGCAGGCTGAACTTTAATCTGCATGATGTGCTGCAGCTTGCCATCATGTCGGGACAGCA 1364 GATCCAGTCCCTTGAGTAAGCCAGTTGGTCACAGTTTCAGA SDC4 RDCR312_B10_at ACCAAAGGCTACCTTGCCTAAAATGTTAGTGGCTGAGGACCCAAGCCTTCTGCCTCTAGC SEQ ID ACAGTGCTCTAAACTAGGCCCTGAAGGATGTGTCGGGTCAAGCCACTGGGGAAGCATCCG NO: AAGGGATACCACCTAGGCAGTACAGGGAAAAAGAGGAAAGGACCCAGGAGGTTGCTGAGT 1365 CACCGTGTGCCCAGTCACATGCCAGTTTCCTCCCAGGGGCTGCTGAGCTTTCAAGTGCTT CAGGGTGCTGAGCAGTC FNDC3B RDCR337_C02_at TATTTACCATTTTACTATCCAGAGATGATAATCACTCTGCTAACATGTTTTTGATTATAT SEQ ID CCTTCCAGATGGATTTTTCTTTTCTCTACTCTTTCTCTGTCTCTCAGCCTCTGCTTTTAA NO: AGTGGTTTAAAATATGTAATTTTCAGTTTTTAATGATTCTGCTAGGGCGAAAAATTGGCA 1366 GCTACATAGGAAAGTTGCTGAAGCGGAGGCAAGGAATCAAAGATTTATCCTTCTCTGATA TAAAAACTTACCCATTTTTTCAAGTGTAAGGCATATTGCAGCCACTAATA KCTD12 RDCR348_G10_at GGGAGGAAGAACTGGTGAAATGAAGTGAGTGCCTTTGAGAATTGAATGAATTTAA SEQ ID NO: 1367 KCTD12 RDCR348_G10_s_at GTAAAACACCATTCAAGTGTCAGAATCATTATTTTCCACCACTTATCATGGTGCTTGACA SEQ ID AGTCTTCCCAATAAATACTGAATGAAC NO: 1368 PTPRK RDCR460_E08_at AGAAATATGCCTTGCCTTCAGAGAATTTATAGAAAGTCTATCTGTCAGTGCTAGGGTGCT SEQ ID AGGGGCTGGGAGGAGCTGAGAGCAGCTCTAAAGCCAGGAAGCTGGACCTAAAACAGATGG NO: CTATTGAGCGAAGTATTTGAAGCTAGATGATGTGTAAGTAATAATATTCTCTGAGCACCT 1370 CTATTATTATTTTTTAGGTTCTCTGCATCAGAATGAGGAAAGAGATTTAATAAGTTGTGA ATTTTAAATTCATGAGAATGCCAATAGAGACC ANXA2 RDCR471_F01_at CTGTGAGAGCATGAAGCTGCAACAAGTCAGTAGGGGAGCAAACAAATATTGATTCAGATC SEQ ID ACGCCACAGAAGAGACAAGCTGGAGCAAGTGCTGTGTGTCCCTCCTGCTCAGTTTGATCG NO: AGGTCACTGGGCCGAATTCCAGGAATTCTGGGGAATGAGTTGGCCCTGTGACTCAGTCAT 1371 TAATCAAGACCATAAAACCAAGGAGAAGAATATCTGCTTTCAAAAAGGTTCTGATAATAA AGATGCAGTACGTGGGTGGAGGATGGAGTACAGTGGGAACCCCTCTTCTC SDC4 RDCR488_B09_s_at AGTGGCCATTAGCTCCCGTCACCACTGCAACCCAGGGTCCCAGCTGGCTGGGTCCTCTTC SEQ ID TGCCCCCAGTGCCCTTCCCCTTGGGCTGTGTTGGAGTGAGCACCTCCTCTGTAGGCACCT NO: CTCACACTGTTGTCTGTTACTGATTTT 1372 FNDC3B RDCR512_D06_at GAGTATTTGTGAATTAAATCCTTTATGAAAAGGTGTCCCTTGTAAATGATTGGGGCATGT SEQ ID TGCCTCTTTTCCTTCATATTTTTAGTTTCTGCTATTCATAAGAAAATAAGAAAAATACTA NO: ACTTCCCTTAAGAGTAACTACTTAATGTCCAAAAACCCCTCAGGTTCTGCAACTATGATG 1375 CACTGATTTATGATGTTTATTTATATACCTCTCAGAAAATTTGAAATGACCAAGAGATTT ACAAATGCAATGTTCAG FNDC3B RDCR512_D06_x_at GAGTATTTGTGAATTAAATCCTTTATGAAAAGGTGTCCCTTGTAAATGATTGGGGCATGT SEQ ID TGCCTCTTTTCCTTCATATTTTTAGTTTCTGCTATTCATAAGAAAATAAGAAAAATACTA NO: ACTTCCCTTAAGAGTAACTACTTAATGTCCAAAAACCCCTCAGGTTCTGCAACTATGATG 1376 CACTGATTTATGATGTTTATTTATATACCTCTCAGAAAATTTGAAATGACCAAGAGATTT ACAAATGCAATGTTCAGCCAAAAATGTTTTT CD44 ADXCRIHRC.1441.C1_s_at GAAGAAGAAAAGCTCCTGACTAAATCAGGGCTGGGCTTAGACAGAGTTGATCTGTAGAAT SEQ ID ATCTTTAAAGGAGAGATGTCAACTTTCTGCACTATTCCCAG NO: 1379 MYL9 ADXCRIHRC.2136.C2_s_at CCACACAAATGCAAGCTCACCAAGGTCCCCTCTCAGTCCCCTTCCCTACACCCTGACCGG SEQ ID CCACTGCTGCACACCCACCCAGAGCACGCCACCCGCCATGGGAGTGTGCTCAGGAGTCGC NO: GGGCAGCGTGGACATCTGTCCCAGAGGGGGCAGAATCTCCAATAGAG 1381 ACTN4 ADXCRIHRC.2359.C2_s_at AGCAGAGGGCGCCACCACCACCTGACGGCTGGGGACCCACCCAGCCCCTCTCCCCTCTCT SEQ ID GCTCCAGACTCACTTGCCATTGCCAGGAGATGGCCCCAACAAGCACCCCGCTTTTGCAGC NO: AGAGGAGCTGAGTTGGCAGACCGGGCCCCCCTGAACCGCACCCCATCCCACCAGCCCCGG 1383 CCTTGCTTTGTCTGGCCTCACGTGTCTCAGATTTTCTAAG FLNA ADXCRPD.16964.C1_at TGGGCTGTCACTTTTGCTGGCGTCACCCTGTGACTTATCCACGTACACCTCGAAGGGGCT SEQ ID CTTGGCGATGTGCTGGCCAGCAAAGAGCACAGTAACCTTATGAGTCCCCGTCAACTCGGG NO: GACGTACCAGACGGAGAAGGTGCGGTTCTTGTCGTTATTGGCGGTCACTTTTGCCTCCTC 1387 CTGGTGTCCGGCCGGGTCCTCCACGTACACCAGCACCTCTCCCTGGCCAGCACCTCTGGT CTCCACAGTGAACTCTACCCGCTTCTTCACAATGCACGTGATCAAATCCTGTAGAGTC FHL1 ADXCRPD.16965.C1_at GGGCCCTATGAACAGACCATTCCTGGGGACCGAATACCTTGCTTTCCACCTGCAAAAAAA SEQ ID GTCTCCCTGGGAAATCCTGGCCCAACAAAAGAGCTTTGTTNTTTCCCCCCAGCGAACAAA NO: GGGTATTTGTCCCTGAATGTGTGCCAAAAAACACGTGTAAACACTAACAAGGAGGCTCTC 1388 TTGGACCTTCGAAAAAAGGGCAATTGGAAATCTCCGGCCCCTTTTGAGGCCCTTGACTTT CATGGCCCTCATCCCCAGTCGATAAGGG WDR1 ADXCRPD.16980.C1_at GAAGGTGGAGGTCACTCTCCAAAGAAGCATCTCCAACTACTCTTGGGCAAGGCCATCTCT SEQ ID CCAGTAGTCTTACGCATGAGGCTAAACCTCTTCTCTTACCTCAAAGATGGCTTCAGTATC NO: CCTCCCGTTACCTNCAACAGGGCATNGAAATGTACCAAAAGCAACACACAGGAGGCCACA 1390 GTGGGGCTGAGAGGACCCAGGTACACATGCTGTTTCCTGCCTGGTTTCTCCCCACCTCTG CCGTGTGTCATCAACGCTCCT SDC4 ADXCRPD.16987.C1_at GAAACTCTGCCCCTCCGGAACAGGAGGGTGACCCCAGGTCCTGGACAGGTGTCCAGAGTG SEQ ID GTCTGATACCCTTGGCAAACCCCCTGCCCCCTCTCCCTCCAGGCTGCAAACTGTTCAGCA NO: TGAGGCTCCAGCAAATCCCAGCAGGAGAGGTGGGGCTGCCCAGCAACTGGTTCTTGTATA 1391 AACATAAACCCATTCGATAATTAGCAAACAGCCCACTTCTAAGATAAACAAATAGGAGAT TTGGACTCCAAAAGC AHNAK ADXCRPD.16988.C1_at AAATCGGTCGCAGCTAGTGCACTTTGTTCATCATATGTATCTGTGACAGGAACTGAGTCT SEQ ID TAAATCTCCCTGTCTGGCACATGGGTGCGTGAGTGATGTGAGGTCACCGTCTAACGCAGC NO: GTGTAATTAGGTGCTGGGACCAGTTGTGTCCATCCCTGGCTGGTTCCGTCTGTAATGCAA 1392 AGTATAGTGTAGGGCATATGGAGGCAGCCGGTATACATGCATTGATTGACTGTTGATACT TTCCGGATGTAA CAST ADXCRPD.1324.C1_s_at GATCAGCTGAACAGCAGCCATCAGAGAAATCAACAGAACCAAAGACTAAACCACAAGACA SEQ ID TGATTTCTGCTGGTGGAGAGAGTGTTGCTGGTATCACTGCAATATCTGGCAAGCCGGGTG NO: ACAAGAAAAAAGAAACAGAAATCATTAACCCCAGCTGTGCCAGTTGAATCTAAACCGGAT 1395 AAACCATCGGGAAAGTCAGGCATGGATGCTGCTTTGGATGACTTAATAGATACTTTAGGA GGACCTGA FOXN3 ADXCRPD.8652.C1_at TAATCGGATGTCAGGCAGAGAAAACGTCGAGGTCACTCGTCTTCCTGAAGGGCCTTGGAG SEQ ID AAACCGCTGCCCCCGTAACACTGACTCAGTCCACTGGAGACACTAATTCCTGAGCTTTCT NO: GGCTTCTTACTGGGAGGCATGACTGGACCCATTTACGTGAAGGCTCCTGGCCGGAGCGGG 1405 GCACGGGGGTGCGGGGGCGCCGCTGCCCTTCAGCAGGAGCCGACAAACTTTCGCGGGCG RAB31 ADXCRPD.8667.C1_s_at GATTGGATTAAAGACCTGGCACTTCAGTAACTCAGCACGCTTCCACTTCACTCAACTTAA SEQ ID GAGAGTTCATTGACAGTGTTAGGATGTGAAGGCTGGGAAACACTTATTTTGCTTCAAGAG NO: TTCCACTTGGCTCTCCCAAATAGGTACCTCAAAAACTGTTAGCAAGCGGCATTTGGATGT 1406 CTTGACAGGGGCTTTGCAGGGATTTTTAGGGTTTTTTCCACATTGTCCACATTAATGGTT GGCATGATTGTGCTTGCAGGCCAAGAAATGATCATACCCCTTGCCAA EPHA2 ADXCRPD.8668.C1_at ATTGTATACAGCGTCACCTGCGAACAGTGCTGGCCCGAGTCTGGGGAATGCGGGCCGTGT SEQ ID GAGGCCAGTGTGCGCTACTCGGAGCCTCCTCACGGACTGACCCGCACCAGTGTGACAGTG NO: AGCGACCTGGAGCCCCACATGAACTACACCTTCACCGTGGAGGCCCGCAATGGCGTCTCA 1407 GGCCTGGTAACCAGCCGCAGCTTCCGTACTGCCAGTGTCAGCATCAACCA LAMB1 ADXCRPD.11010.C1_at ACTGGCACTGGCCTCCGTTGGGATCACACACGGAACTTAACGAACCCTGAGGGTCGCATT SEQ ID CACAAGCCAGGCCTGTCTGGTGTAACAGGGCAGAAATGCTAAAGATGATATTTCTGCAAA NO: CATCTGTCATCGGGGTTTTCACAAACGCTTCTGCTGTTCTCTAGACATCGGTATCTCTGA 1408 AAGGTTTCCCAGGCACTGTTGGTGACCACCCCATCTCCTGAACCTCCCACGGTGAAGATG TCCAGTGATTTACAGTAT FHL1 ADXCRPD.11024.C1_s_at TGTGCTTTCAAATAACTAACACGAACTTCCAGAAAATTAACATTTGAACTTAGCTGTAAT SEQ ID TCTAAACTGACCTTTCCCCGTACTAACGTTTGGTTTCCCCGTGTGGCATGTTTTCTGAGC NO: GTTCCTACTTTAAAGCATGGAACATGCAGGTGATTTGGGAAGTGTAGAAAGACCTGAGAA 1409 AACGAGCCTGTTTCAGAGGAACATCGTCACAACGAATACTTCTGGAAG IGFBP3 ADXCRPD.2051.C1_at GGCTCCCGAGATGAAACCCGACGTGAACACCACACCCGCGCCCGCCGCACCAATGATCTG SEQ ID ATAACTCTCTAGACAAAATAGGGGGCTCGGTCGGGAGAGTCTGAGCCGCCAAATCATCTC NO: AACACCGCTTGCTGCCTCGGCGCCTCNCTGTCGATGATGACATGCGTACACCTCTCTCCT 1411 CACGACGACAAGGAGCCTTAGGTGGGACGAANACACAACGCGCACGCACCAATCGCGCGA GCATGCACACGTATAAGACCC RAB31 ADXCRPD.2065.C1_at AATGCGCCGGCCTAACAATAGTTATAAAAAATTGGGGGGAGGACAACCTCCCCTTCCCCC SEQ ID TCCCGGATCCCCCGCCCGCCTTTTTTTTCCGCACTATTATCCGCCTCTGCCCCGCCGCCT NO: CAGAATACCTCTATCCCGCCGCGGAGAAATTNATTCGCGCCCCGTATTTTCTGCCCGCCG 1412 CGAACACGCCCGCCAACCAGTATTCTCGGGAAAATAATATAATGGGACTCAAAAACACCG CTCCCCGCCCAAATACGAACGTCGCGGTGGTTATTACTTCTCGCCC ADAMTS1 ADXCRAD_BM930186_s_at TCCAGCAGCTGGTCCAACAGTCGTATCCTGGTGAATGTCTGTTCAGCTCTTCTGTGAGAA SEQ ID TATGATTT NO: 1413 CKAP4 ADXCRAD_CF130614_s_at CAAGGAATGCACAGGTTTCGACTACCAGAAAGGGGAGTCCTTGGGTTCTTTCAAAAAATT SEQ ID CGTGAGGAGAGCTGTCTACAGTGGAATAGGGGGTCTCCCTGGGGAATGCAGGCCAAGTCC NO: TTTTATTTTAACATGATGTCCATGAAGAGGTTTGCCGTCTGGGCAGCCCTGTCGGCAAGG 1414 AGCGTGCATACTGCGTTTGTGTAATTGTTTGCTGTATCTCCCTTCCCTCTGAGCTGTATT GTTCTTTAATGGCTGTCTTGCC FOXN3 ADXCRPD.10462.C1_s_at GTTCTGTTATGTTCATGTAAACCTAAAGAAACAGTGTGGAGGCAGGCGCGATCAGCCGAA SEQ ID CTCTAGGGACTTGGTGTTGCTTGGAAGGCATCCATACCTGCATTTTGCATTCTTCGTATG NO: TAATCATATTGCCAAAGACAAACTATTTCATCATTTATTGTAAATAACACTTTTCCCCAG 1418 ACCTACCATAAAGTTTCTGTGATGTATTGTCTTCCAGTTGCAAT MXRA7 ADXCRPD.17734.C1_at AAAGGCCTCTAACCTGCTGGAAGATAGGGACCAAGTTGAGTATTTTATTTCTTCTGTCTA SEQ ID CAGCATCCAGCATAGTTCTAATTAAATACAATTAGGCAAGTACTCAAATAAGTCTTGCCT NO: AATTATATTTAAAGTAAGTATCCTGCTTAAGTGAGAGAAATTCTTGGCAGATCTTACCTC 1422 TAGTACTATTGTTTAGTGCCAGGATGGAAGGTGAGTCTCTGAATTAGACTTTTTGCTGAA AGAACGCTCCCAGCTGGGCATGCT FOXN3 ADXCRPD.8765.C1_at TCTTGAAGAAGGTACTGCCCGGCCAGATGGGTGGACCTGATGTGCTTTGATATGCCTGAG SEQ ID GACAGGTGGGAGGTGTATTGAACACGTGTGGGTGTGGGTGATAAGGTGTCTTTTTCAAAG NO: CCTGAATTAGATTTTGTCTATACTCTGGGTCTATGCACCACAACGACCCTTTCCCAATAC 1423 TCTGACTCCTCTCTTTGTCCACTTTCTTAAAACACTTATTCAATGATAAATTGTGTCTCA CTGAGTTTTTCCACCCAGTAGGTGCATTTGCAAAAT PTPRK ADXCRPD.11104.C1_at GGCAGTGGATAATCGTCCGGCCTTCCCCTTCCTCGCATTCCTCCTGCCACTTTTCCACCT SEQ ID GAAGTATCAGTTTCAAGAATGACCTTTTGGAACCAGGCACTTCTCGATGAGAAGCCCATC NO: CTAGGTACTGAAACTGTTGCACCATCAGATAACCTTCCTGTGGTCTTGTTAGATTGCATA 1425 TCCTAAAAATCCGGTTGATCACATCACAGTCCATTGAACAAGACATACATTCCACTTGGA TGGGGCCATATCGTAGCATCCCTTCCTCTGGCCAGTACTGAGGGCAGCCCTG ARID5B ADXCRPD.11117.C1_at GATATTCACAAATCCCTTCACAAGGCCCACGTGCGAAGTGAATGATCTGGAGGTGCCTGG SEQ ID GCATCTGTGTTGGAAGGGAGTCAAGACTCACCAGCCAGTCAGTTTGTGGGCTAGAGTTGT NO: CCCACAAAAATCAGGCATGTTCACCTCCCCTCTGGGCCCCTACAGCTGGGACTGATCATA 1427 GCCTCAGATTAGAAGAAATACTGACTTCTAACTCTATAAGCCAGCACTCCTGGGTAAGGA GTGAAGCTCTGTTGGCCATGCC KDELR3 ADXCRPD.11126.C1_at AGAGGAGGGACATTGTTCCAGATTGGGGTTGACTTGCCCATCATGAGTCTTGCCCTCAGG SEQ ID CCTTGGAGAACAATCATTTATGTTTTTTATTTCGTCGGTAAGACACCTTAAGGTTTCTTG NO: TTGCAGTGAGGCACCATCTTTGTGCAGTTGGCCGAGGTTTTTTATGACCTTACAATGGGT 1428 CTTTAAGGGCGATCTATTGATGA ELF4 ADXCRPD.11148.C1_at AGGCCTCCCAGAGAGTAACTTGGAGGTTCCATTTGCTATTGACTGGATTGTGTTTGCTTG SEQ ID AGGAGCCTGTGACCACCCGCAGGGACAGGCAGCCTAGGATAAACTGGACCACCCCTGAGT NO: AAAGCACTCCACTCAGTCCCTTGGTCCCCACCCCTCAGTTAGAACTGCTAGGCTTTGGGG 1430 GATGGGAGGGTGGCAATTATTCTTAACCTCCCGAAATTCCTGATGACCCGATAACAAGGA GGTATTTAGACATAGAATGAGGAGCTAATCTTTTTCCTA VCAN ADXCRPD.2145.C1_at AGGAATGACTCTAGCTACAATAATACACAGTATGTTTAAGCAGGTTCCCTTGGTTGTTGC SEQ ID ATTAAATGTAATCCACCTTTAGGTATTTTAGAGCACAGAACAACACTGTGTTGATCTAGT NO: AGGTTTCTATTTTTCCTTTCTCTTTACAATGCACATAATACTTTCCTGTATTTATATCAT 1431 AACGTGT VCAN ADXCRPD.2145.C1_x_at GGAATGACTCTAGCTACAATAATACACAGTATGTTTAAGCAGGTTCCCTTGGTTGTTGCA SEQ ID TTAAATGTAATCCACCTTTAGGTATTTTAGAGCACAGAACAACACTGTGTTGATCTAGTA NO: GGTTTCTATTTTTCCTTTCTCTTTACAATGCACATAATACTTTCCTGTATTTATATCATA 1432 ACGTGTATAGTGTAAAATGTGAATGACTTTTTTTGTGAATGAAAATCTAAAATCTTTGTA ACTTTTTATATCTGCTTTTGT CETN2 ADXCRPD.2161.C1_at TAAACCGCCGCTTATTTACGCCACAGCGCGCCGTCACACTGTATCTATATTTTGTATTCC SEQ ID CCCCGTCGCGACTCGTATCTTATCATACCCAAAATTANCGCGCCCGCCCCAGCAGCTAGA NO: CACAACCACGACATCGTATATATGGGGCGCTATATTAGTGACATNCTAACAGCTCGCGAG 1434 TTCGGTGCGTCGCCGCCGGGAAG KDELR2 ADXCRPD.1509.C1_at AGAGCTGTGCTGACTATGTTACATCCTAAAAAAACTATATAAAGCAATGGATAATGTCGT SEQ ID TTATGAATTAAGGTGGGAAAATCGGGTTGGAATTGTGTCAATGGACAAAGGCCGGAGGGG NO: CGAAATTAAGTCACTACTCTGACACCTCGGATTTGGGAGAAAATATGCCGCTGCAATAGA 1435 TGGTATTGGAGGAAAAGATGTTTGTGAACAATAAGGGATACGGAAAGATAGCGCCAACAT CAGGAGCAACGTG LPP ADXCRPD.11183.C1_at GAATGACCAACAATTTGGCTTTCCTAGAAAGAGAAGAGAATATCTGAATTCCCTGTAAAC SEQ ID TGGTAAATCCTCTACCATCAGTCCTGAATTCTGAGGGGGCCTGATATTTAAGCAACAAAA NO: CTTAGAAGGTTCCACCTGTTATTCCTAGCTCTGTCACTAAAAATCGTGTCCAAACAGAGG 1437 TAATACGAATGTGTTACCCGTTCCCGAAATTNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNCCCAGAGCACAGAATGGATCCAGTGTAGTAGTGCAGGTGACCA LEPROT ADXCRPD.1565.C1_at TTGCCTGCCAACACAAGGCCGCAGTCCCCATTTGATCACAGCCACACGAGCAAGAATAAC SEQ ID AGGAAATCCAAAGGCAGAAACAACAATTCCAGTAGTGAAGAAATATGCCAGTTCCCGACA NO: GGCACTACTGGTTGCATCTGAGTCATAGGTGACTCTTTTGGCAATGAAATGGGGGATGGG 1442 GGAGATGGCGTGGAAAATCAGGACGAATAAGGGCCAGTAAACGCCATAATCCTCTAAGGC ACATCCCAGCATAAGAAAAGTCAGTCCAATAGCCCCACTGAAGGATAATGGCCCGA CYR61 ADXCRPD.10589.C1_at GGAACCGCATCTTCACAGTCCTGGTCAGCTGGGGCGTGCAGCATCGGCCGTCCACGCAGG SEQ ID AACCGCAGTACTTGGGCCGGTATTTCTTCACACTCAAACATCCAGCGTAAGTAAACCTGA NO: CTGGGTTCGGGGGATATCTTGGTACTTGCTGCATTTCTTGCCCTTCTGTAAGAGAAAGGC 1443 GAGAAGGCAAGTTAGGGGTGATATTTCTCTTTCTTCAAAAAGATGTTCACATCCCAACCA CCTGCCAGGCAACAGTCTACACGTCCCTTAAGGAACTTACTTTCAGGCTGCTGT CDC14B ADXCRPD.9445.C1_at AATATCGAATAGTGCAAATTGTATAATTACAA SEQ ID NO: 1447 CDC14B ADXCRPD.9445.C1_s_at ACAGCGTATATTTCTAATCATATTTTTTAAAGCCAAGAGAACTGGTTGAATGAATGTTTA SEQ ID TTTTCCTGAAGGTATTTTTAAGATAAAGCTTCCTAATGGCGTGTAAACTTTGCATA NO: 1448 EPAS1 ADXCRPD.17826.C1_at CAGTGTAGCCAGTGTGCTCGGCGTCTGAACGTCTCAAAGTGGCCACAGCTGACAATGACA SEQ ID GCTGACAAGGGAGAAGAAAAGGAGTAGCTCGGAGAGGAGGAAGGAGAAGTCCCGGGATGC NO: TGCGCGGTGCCGGCGGAGCAAGGAGACGGAGGTGTTCTATGAGCTGGCCCATGAGCTGCC 1450 EPAS1 ADXCRPD.17826.C1_x_at CAGTGTAGCCAGTGTGCTCGGCGTCTGAACGTCTCAAAGTGGCCACAGCTGACAATGACA SEQ ID GCTGACAAGGGAGAAGAAAAGGAGTAGCTCGGAGAGGAGGAAGGAGAAGTCCCGGGATGC NO: TGCGCGGTGCCGGCGGAGCAAGGAGACGGAGGTGTTCTATGAGCTGGCCCATGAGCTGCC 1451 TCTGCCCCACAGTGTGAGCTCCCATCTGGACATAGTG POFUT2 ADXCRPD.9474.C1_at TGAGGAGGGACAGACAGCTCTTCCTTTCGGAGCCTGGCTAGTCTAGGACATCACCTTGCT SEQ ID GTGTCTTCTCAAGCTTTTAAAATTGACCCTGAACGTGTGACAGGGTCCTATGGTGTTACT NO: CAAAGCTGTGCAGGGTAAATGATGACATATTTATTCTTTTTCCATTTGTTCTAGAAACAG 1452 TGCCTTTTTCATCAGTTGCATTTTCCAGGCTGAGAGCTGTATAAAACATTTTGGACTGTG ACCATGTACCTTCCTTTTTAA COL6A1 ADXCRPD.17873.C1_at TGTGAATGCAAGTGCGGCCCATCGACCTCCTGTTCGTGCTGGACAGCTCAGAGAGCATTG SEQ ID GCTGCAGAACTTCGAGATTGCCAAGGACTTCGTCGTCAAGGTCATCGACCGGCTGAGCCG NO: GCGACGAAGCTGGCTCAAGCTCGAGCCAGGCCAAGTCGTACGCGGGCTGTAGCTGCAGTA 1454 CAGCCACAGCCAAGATGCAGGAGCATGTGAGCCTGCGGCAGCCCCA YPEL5 ADXCRPD.11244.C1_s_at GAAAACTGTACTTTGTACCCTCACATACAAAGGGATCAAATTTGACCTGGTGTTATTTTA SEQ ID GCCCCAAATTTATGACATTACACAATATTAAAATGTAAATGTTTCTTTACCCAAACTACT NO: TCTAGATATTCTAGTATTTGCTTCTGGTGGAATTAAATGACGGTAAAATTGGCTAATTAT 1457 TTGAATGAATGAATGGATGGATGTTTTGCATGCTCACTTTCTAGGTCCTTTGTCTAGAAA GGA RBPMS ADXCRPD.10645.C1_at GCGAGGTTGAGCTGTCATGAACTCTGGAGATGTGTCAACTGACAACACCAGACTGACTTT SEQ ID GGCTTTGACGAAGTCTGAATAGAATTGGTTCCAAATGCCCACTGCCTCCGTCTCCTGTGG NO: GGTGTGGCAGGACGTCTCACAGTGAGCACACGCCATTTGGGAGCTCATGGTATGTGGTCG 1462 GTTTG MALT1 ADXCRPD.2292.C1_at ATTATTTTAATCATCTTCAGTGCACTCCACTGGCTCAATCGTCCTTCCAAGGATGATTTC SEQ ID AAACCTCCTGGCAAACTGGAACGGGAGA NO: 1463 SLC20A1 ADXCRPD.10696.C1_at TATTATCATTGAACTTCGGTAAAGCATTAATTGTGGCATCTTTGTCAGATGTTTAGATAA SEQ ID GATGGTTGCCGTACGCATAGTCTGCATGTTGTATTTTTAGTCTTTGAAGATATGAAGTCA NO: GGTAAGCAACATCCTAACATAGTCTATTTCTTGACATCTCTTACAAACGTAGAGTATAGC 1465 CTATCCTCAGGTGTGTGCTGAAGTTTATATTAGGGCTTTTGGGTACCTTAGAATGTGGGT ATTGCAGTCTTTATTCAGGATGTTATCAGTCACTGGTACAGTTAGTCTTGTTAT MDFIC ADXCRPD.1686.C1_s_at TTTATGTTCATAGTACTTTTCCTCTTGTCTACTCCAGACAGTTATTCCATAAAGCATTTG SEQ ID TATAATTAAAAGGAAAACAGAAAAAGGAAAAGTAGGCAAATGTGAAAATAGTTTCAATAT NO: ATCTTATGATTTCTTAATGTAAAATGTTTTGTTGAAGTATATGGCTATCATGACTAAGTG 1466 CTAGAATTTATAGTTACAGGCGGTGTCCTTTTAAATGTGGAAAGGCTTTTAAAATATTTT AAAACTGGACCTGTATTATCCTGAATACACT SYNJ2 ADXCRPD.17920.C1_at TGAGAGCCGAGTGACCGTTCCTGCAAAAGTTTACCCAGGCCAATT SEQ ID NO: 1467 SYNJ2 ADXCRPD.17920.C1_s_at GAATATCCCCTTCTGACTCATAGTCCAAACTTGTGAAGTCAAAGTTTTCCTCCAGCAAAC SEQ ID AGGAGTTGGCAGTGGGAGACACGGGGGCCATGCTGTCTCGTTTCCGAATGATCTCCTCTC NO: GCAAACCTTTCAGCCAGTCCTTGGTCTTCGGTCTAATCTTCACTGCTCTGCCTTTCACCT 1468 TCATACCGTCCACGTCCAGGACACTGAGAGCCGA POFUT2 ADXCRPD.17928.C1_s_at TTCATCAGCCATGGCGGCTGGCAACGCCGAGGACAGAGCGCCAGCTCTAGAGGCGTGGGG SEQ ID CCTCATTCTGGGCCTGGGACCCTGCGAGGGACGGTCACATGTCCAGCCCAGCTCCCGGCT NO: GGCAGTAGACGGTGACTCCACGGCGACAGAACCTGCATCCACCCGCGCCTGTCGGGTCCG 1469 GGGAGCGGCCCTGGAGGATCACTCCTCAGTAGGTGATCTTCCAGTGGGTGGGTTGCTCAC ACGCCTTCTCTT VCAN ADXCRPD.8962.C1_s_at GATTCATTTCACACTTCTGCAACTACTCAGGCAACCAGACAAGAAAGCAGCACCACATTT SEQ ID GTTTCTGATGGGTCCCTGGAAAAACATCCTGAGGTGCCAAGCGCTAAAGCTGTTACTGCT NO: GATGGATTCCCAACAGTTTCAGTGATGCTGCCTCTTCATTACAGAGCAGAACAAAAGCTC 1471 CCCTGATCCAACTAGCACACTCTCAAATACAGTGTCATATGAGAGGTCCACAGACGGTAG TTTCCAAGACCGTTTCAGGGAATTCGAG RND3 ADXCRPD.11316.C1_at TTCCACAAACTATGTCATCAGGCTCATTTTTCAAAACCAATGTGCACAACACCTGGTCAA SEQ ID ACTTCTGCGTCAACTACATTCCGTGTCAATAAAATGTTTGCTTTGCCAAGGGAGACTCTG NO: AGAAAGTGACCAATATGTAGCAACTGAGAAGTCATTTAAAGGACATCAGA 1472 PLOD2 ADXCRPD.2305.C1_s_at TGAAGGACTTCCTGTTAAAAATGGAACAAGATACATTGCAGTGTCATTTATAGATCCCTA SEQ ID AGTTATTTACTTTTCATTGAATTGAAATTTATTTTGGATGAATGACTGGCATGAACACGT NO: CTTTGAAGTTGTGGCTGAGAAGATGAGAGGAATATTTAAATAACATCAACAGAACAACTT 1473 CACTTTGGGCCAAACATTTGAAAAACTTTTTATAAAAAATTGTTTGATATTTCTTAATGT CTGCTCTGAGCCTTAAAACACAGATT CORO1C ADXCRPD.11328.C1_at CAAGCAATTGCAAAAAACTCTTTTACCACCTGTGACAATATCCCATTTTATCTGCATAAC SEQ ID TTTGGCATCTTACGTCACTGTCTTGTACAGTCTATGCCAACAGTTTCAGTTTTTTCTCTC NO: CTTTTGGGGCGAGGGGAAATTTCATGTGGTCAAATGGCATTACAAAATTACTGAAAAGTC 1475 ACTTTACTTTCCCTAAAATCTTCCAACAGAGAACATGTCAACTGTCAATAAGCACATACA C CNN3 ADXCRPD.2332.C1_at CATATCAAATGGTTTCTAACAGGTATTGGTTTGCCTAATTTTCAAAACAAACCTCCTTGA SEQ ID TCCACGGGGGCCCTTTTGATGAATTACAATGGGGGAACCTCCATTTCCCCTTTACCCGAC NO: GGCGGAACACCACAATTCTTTTTTCCCCAAGCGGGGTTGCTCTCTCTTTACCAAGCAATC 1476 CTTTGGTTACCCAATCACCGTGTGCGCCTTGTGTGGTAACACTTTTTCAACGCGCCCTCA TGCGGAGACGAAATCGCACTCTCTTTGCG ARID5B ADXCRPD.2347.C1_s_at AAATCTTAAAGGCAGACCACGCAAAAAGAAACCATGCCCACAAAGAAGAGATTCATTCAG SEQ ID TGGTGTTAAGGATTCCAACAACAATTCCGATGGCAAAGCCGTTGCCAAGGTGAAATGTGA NO: GGCCAGGTCAGCCTTGACCAAGCCGAAGAATAACCATAACTGTAAAAAAGTCTCAAATGA 1477 AGAAAAACCAAAGGTTGCCATTGGTGAAGAGTGCAGGGCAGATGAACAAGCCTTCTTGG PTRF ADXCRPD.10702.C1_s_at GACAGAGCAGAATGAGCCCTCACCCTGGCTGGGGGTCCAGCACAGGCTGTATCTGCAGAG SEQ ID GGTCCCAGAGGAACGCTGGAGCCAAGAGAAGCCCTGGGAAGGAGGGGTGGGGAACGACAT NO: GCATGTGAGGGATGGCACACTGATGTGTTTATGCACCTGCACACAGGAGCGCATGGCCAT 1478 GGCTT SYNJ2 ADXCRPD.1723.C1_s_at GAAATCTACAAAATCACTGCCACTGACTTTTACCCTCTTCAGGAAGAGGGCCAAGGAGGA SEQ ID GGAACGCCTCATAGCTTTGAAGAAAATCCTCAGCTCGGGGGTGTTCTATTTCTCATGGCC NO: AAACGATGGGTCTCGCTTTGACCTGACTGTCCGCACGCAGAAG 1482 CTNNAL1 ADXCRPD.129.C1_at GACAGACACACTGGGAGTCGTGCTGCGCACCCCCCCTATTATTTTCGCGCACCCAATTTA SEQ ID AAGAGGTGGGCCGGCCGCGCCCACCCGTCCATCACCTCGATATGCACACTACCTCCGCCG NO: TCGGGGCCCTCGCGGCCCGCCATGCTGTTCGCAAACACTCACCGCCCGGCCGCGGGTCCG 1484 CGATGCTGCGCGTGTGTGAGAAGTATGGTGAGCGCGATATGGCGGCAACACCACTGTCGA CTTGTCTCG RABAC1 ADXCRPD.9642.C1_at AACCCGTGTGAGGTGTCTTCTGGGACCTGCCGGCCTCCCGGGCCAGCTGCCCCACCCCTG SEQ ID CCCATGCCTGTCCTGCACGGCTCTGCTGCTCGGGCCCACAGCGCCGTCCCATCACAAGCC NO: CGGGGAGGGATCCCGCCTTTGAAAATAAAGCTGTTATGGGTGTCATTCAGGAAAA 1485 RABAC1 ADXCRPD.9642.C1_x_at GAGGAGCTGCAGATGGAACCCGTGTGAGGTGTCTTCTGGGACCTGCCGGCCTCCCGGGCC SEQ ID AGCTGCCCCACCCCTGCCCATGCCTGTCCTGCACGGCTCTGCTGCTCGGGCCCACAGCGC NO: CGTCCCATCACAAGCCCGGGGAGGGATCCCGCCTTTGAAAATAAAGCTGTTATGGGTGTC 1486 ATTCAGGAAAA GALNT2 ADXCRPD.12003.C1_at CTAGTGCTGTCATGTTGGAGGTGTCTGACCTTTGCACTAAGTTTCCCCACTTACACTAAA SEQ ID TGGGGATAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NO: NNNNNNNNNNNNNNNNNNNNNTAATGCAGAACTACTCACTGCTGCTGGAGTGCGCTGTTA 1487 TATTCTTTATTAGGTCCTCAGACTTTTTCTATGCCTAAGCTTGAGGGTCTCTCTCAGCTG TGTTTTTC EPAS1 ADXCRPD.3002.C1_at ACCTTGTGGGCAGACGACAGGCTGTAGTCCTGGTACTGGGTGGCGTAGCACAGTGGCGGG SEQ ID AACCTGCTCTTGCTGTTCTCCCCGGAACTGATGGCAGATGGAGGCTGTGGCACCGGCAGA NO: TGTCTCAGGGGATGGCCCAGGCCCCTCATGGGGTATCGGGTGAACTTATCATTGGGTACA 1488 TTTGCGCTCAGTGGCTTGTCCGGCATCAAAGGGCAGCTCCCACGCCTGAGGTTCTTCATC CGTTTCCACATCAAATGTGAGGTGCTGCCACCAAGTTGGGTCTCCCGCATACGCAA SVIL ADXCRPD.12020.C1_s_at GCTTCTGGGTGGCCAAACCAGTTACCCAATCTGCTGGAGACCCAAAAGAAGATGAACTCT SEQ ID ATGAAGCAGCCATAATAGAAACTAACTGCATTTACCGTCTCATGGATGACAAACTTGTTC NO: CTGATGACGACTACTGGGGGAAAATTCCGAAGTGCTCCCTTCTGCAACCCAAAGAGGTAC 1489 TGGTGTATGATTTTGGTAGTGAAGTTTACGTATGGCATGGGAAAGAAGTCACATTAGCAC AACGAAA FLNA ADXCRPD.3034.C1_at AGTACAATGAACAGCACGTCCCAGGCAGCCCCTTCACTGCTCGGGTCACAGGTGACGACT SEQ ID CCATGCGTATGTCCCACCTAAAGGTCGGCTCTGCTGCCGACATCCCCATCAACATCTCAG NO: AGACGGATCTCAGCCTGCTCGTACGGCCACTGTGGTCCCGCCCTCGGGCCGCGAGGAGCC 1490 CTGTCTGCTGAAGCGGCTGCGCAATGGCCACGTGCGCATTGCATTCGTGCCCAAGGAG PLAU ADXCRPD.12085.C1_s_at AGAATTCACCACCATCGAGAACCAGCCCTGGTTTGCGGCCATCTACAGGAGGCACCGGGG SEQ ID GGGCTCTGTCACCTACGTGTGTGGAGGCAGCCTCATCAGCCCTTGCTGGGTGATCAGCGC NO: CACACACTGCTTCATTGATTACCCAAAGAAGGAGGACTACATCGTCTACCTGGGTCGCTC 1491 AAGGCTTAACTCCAACACGCAAGGGGAGATGAAGTTTGAGGTGGAAAACCTCATCCTACA CA RAB31 ADXCRPD.2471.C1_at GGTTGTAAAGCCTCATTGTAGACAAGGCCTGAGCATCCACAGAGAAGATACAATGTTTAT SEQ ID ATGAATCCTGGTGTGCCCAAGTGTGATCTACTCTCTTCACTGACTACTCTGAGTGCTGAT NO: GAGAATATATATATTATCCTCTGACTGGCTTGAATAGCTAAGACAATACAGAAAGGTAAC 1496 AGAGTGGTTTCACACCCTCATGTGCTTCTGAAATAAAACCATGGGCTCATTAGTGGGTAG CTCACTATCTGTGGCAA ATP2B4 ADXCRPD.11491.C1_at TTCATTTTTCTTCCCCTCTGCTAGTTTGGAAGTTATATTATACCAAGTTTTTTAGTATTA SEQ ID GCCTAGAAATCTTAACATAAAGACTTCTAATAAGCAATATCTTTAATTTTTTTTNCCTAC NO: CCAATACTAGATCATGAGCATTTTCCCACATCATAAAGAATTGGTCACAAGTCAGCCCCA 1498 AACATAGTCCAGTGGAATCCAATGATA ALCAM ADXCRPD.1829.C1_at AATCCTGGGAAAGAAATCGCTGTGCAGTGTTCTCCCAGAAACCAGGCTTCTGCTTGAAAG SEQ ID AGCAAAGTTTAAAAGTCTAGTCACAAGTAGCCCATATCTGGTCTACTTCAAAAAGTTTCC NO: ATTTATACTACCACCTTAAAAATTTCCTCAAGCATAAAACATGTTTATAAAGTTACAAAT 1499 TTGAATGTAACTAAAGATACATAGACATTTTATTATTACACTTTCATGTACTGCTTGATA A ARID5B ADXCRPD.10890.C1_at GACACACCAACACAGTGAAATACAGTACTTGAGAATTCATGCACCAGGTCAGAAAGTTGT SEQ ID AAAGTTAACATCGAGTTTTAACAAACCCTTCTGTATATGCCCTGATAAACAAGTGAACTT NO: AAGAGCTTCTAGCTAGTAAATAAATAAGTCAGTCCTGTGGCAAATATTACAAGTGTTGAA 1503 TCACTTACTAGAAGAATACTTAATTCCGAAACTCGGTTGGGCTGGTTTTATTTTTTTATC ATGTGGAGTTGCCAAACATTAAACCAGAA TPM4 ADXCRPD.295.C1_at GTGTGGGGGCTGACTAAAGTTTACAATTCCAACTAAAAATCACCCTGCTTCTGGCTTATC SEQ ID TGAATCCCTTACCCACCCCACCCCACCACCCTACTCCTATTTATTCAGCACCACACTACC NO: CAGGAAATACACTAGCAAATTGTGCAATGGAATAAAATCCACACTTTAGATTCTTGCAAC 1505 TGTATCATATGTAATAGTATCACTTTTTCTACATTTTGGCGCAAATAAATTTTTACATAA ACTACGGGAGGCCAAGGGAGCTCGATATAAAAAACATGT NFIB ADXCRPD.9768.C1_s_at TCCATGTCACAAGGGTAAAGCTTACAGTTTACAAACTGGGAACGCCAGGGTGTAGGATAT SEQ ID AAAAACGCACTCTTGAGAAAACAAATGTAATCAGGGTGCTGAAAACTTGCATGGTGCTTT NO: CAGACATTAGCCTTGTTCAACAAATTTCTTGTATTGACAGATCCATAGTGTGCATGGGCA 1507 GACACATTTTGCCTCTATGTCTCTTAAAATTTTAATTAAAAATACTCTTTCCAGTAATCC TAATTTGCACGAAGATATAATGTCCACATTACGTGCCTTGC EHD2 ADXCRPD.3133.C1_at TGGTACAAGAGACAATCCCGGCATTGGACATGGAGTTCGGGCTGATCTGTCCTACCTGAA SEQ ID CACCGCTTCCGTTCCTGGGCTGTCGTCTTCACCGCCTGGTTTTCCATGGAAAGGAAGCCT NO: CCCCAGTGGCCTTTTGAAAAGGCACTGTGGCGTGGTCCGATAAGTCTCTGCAGAGGCACC 1510 AGGGATGCTTTCAGGACACAGCACCCAGAACGGAGGCTCGATGGTTTAAAGTTTGGCTCT GCATACACCTTAGGGTCGCTGACACAATATCTGGACACGACGTCAGACATGATAT FOXN3 ADXCRPD.12156.C1_at CCGAGCTGACGAGTCATAGATGCATAATTGCAAGATATAACCAGTAGGAGAGAGAGAATA SEQ ID CACAAGGAGTATAACCACCATCGGCGGTGCTCTCTCAAAAGGA NO: 1511 FOXN3 ADXCRPD.12156.C1_s_at AAGGTGCAGCACCATAGACACATCGGTTTCGGCTGTTAAAAGATGGATCGTTTTAAAAAC SEQ ID TGTGTTTTCCTTCCTTAATTTTTGGTCAGTGAAGCTAGCACTTGTTTGCTGAACTGTGGA NO: AGAACTGCAAGGTCACACACATTATTCATGATAAAGCAACCGAGCTGACGAGTC 1512 P4HA1 ADXCRPD.11500.C1_at AACCCAGACTACAAGGCAATATAAAACTTTTTTTCAATAGTCTTTTGCACTAATTTTTTT SEQ ID GGCATAATTAAAAGTTGTACACATTTTTCAACTGTTTTACCATCTAAGTTACCAAAACAC NO: AAAATGGCCAATGTAATTATCCGCCTACCAAAGTCCTGATTTTCAGTACTTCAAAATAAA 1513 ACTCATTTCAAAATGTCAATAAAAACAGCACTACCCATTTAAAAGAGACAGAAATAGTCC TTTTCCTAGTTAGTCTATGTAAATCTAAGAAACATTTGTCATCAGCTATCAAAA AHNAK ADXCRPD.3149.C1_at GATGGTCAGCCCGTGGGAGCCACTACCCTGCCAGTTGGGCAGCAGCAGCTCCCGGGTTGT SEQ ID CTCCTCCTTCTCCATCTTTGCAGGATTCCGCTCAGGAGCGAATGCCTTGCCAGGAGCCCG NO: CCCCTCCTTCCTCTCTTCCCCTCAGTCTCTCTCGTCGGGAATCTCGGTCACAACCTGAGG 1515 GCTCAGCCCCAGGGCACGGCCATAGCCGGCGCGAGGCCCAAGGCTGCGGTGCTGCGGCTA CTGGCGGCGACGAGCCCCGTTCCGGGCGGGTCTGGCAGAGAGG LAMB1 ADXCRPD.12165.C1_at TGAAAAGCATACACCCAAGTTTTACTTTTGAAATCCTAAGGTCTTGGTTTTGAAAACCCC SEQ ID AGGCGCTAAGGAAATTACATGTTTTAAAATCCTAAAGGTTGGGGAATTAATATTCTAAAC NO: TTCAAATTTGTGAATAATCATGACGTTATGGGCAAATACATATAAATAAACATATAACCA 1516 GAACACGTCTTTCCCCTTTATCCAATGGAAATACGATCAAGCATCACTCTTAGCAGAAGA TACCAGACACTTGTAGGGACACGAAAAGCGATAT AMOTL2 ADXCRPD.2508.C1_at TTGGGAACCACTTCGGGTGTTGCGATAACACCCCTCCACCCACGTGGGGCATAACCCTGG SEQ ID GGCTACATGCCAACCCCCAGTGGAAACACTTCTCGAACGTTTCCGGGGAGACACATTACA NO: TCAGAGAAAGCCCCTACTGTCGCGGTGTGAGG 1517 AMOTL2 ADXCRPD.2508.C1_x_at CGGAGCTCCCCGAAGTGGCGTTTTGGGAACCACTTCGGGTGTTGCGATAACACCCCTCCA SEQ ID CCCACGTGGGGCATAACCCTGGGGCTACATGCCAACCCCCAGTGGAAACACTTCTCGAAC NO: GTTTCCGGGGAGACACATTACATCAGAGAAAGCCCCTACTGTCGCGGTGTGAGGGCCCCC 1518 CCCACCGTAAAAATCTTTTTGGTGGGGGCGTGGTGGGACCTCTATAATCA YES1 ADXCRPD.12191.C1_at CTGATTATCAGGTTTTGGCTGGGTTTTGTTAACTGCTGAGCTCTTTGAACAAATAAAATA SEQ ID TTTGGNCTACAAGTGCTCTGATTATGAGGTGGGTGAACCTGTAGCCTTGCCAGTCACCCT NO: CCTTTACCACCTTAACAGGTCCTCACTATTTAAAAATCACTGTTTTGAGTTCCCTGTTAG 1519 GAGACTCAGATTCTCCCAATAAGGCATTGCTAT TFE3 ADXCRPD.2523.C1_s_at TTATTGCTCCGCATACTGAGAATCTAGGCCACCCCAACCTCTGTTCCCCACCCAGTTCTT SEQ ID CATTTGGAGGAATCACCCCA NO: 1520 CAPN2 ADXCRPD.2526.C1_at GGCACGAGAATGTACTCTCCTGGCGGCAGCTTGAAGCGGTTGAGCACCTCCCGGAGGTTG SEQ ID ATGAAGGTGTCTGAGCGCTCCCTGGCGCGATTCGTCAGGAAGAAGTTTTTGCTGAGGTGG NO: ATGTTGGTCTGCCCACTTAACTCCTCTGGAACCTCATAGATGCCAAAGCCGATGGTGTGC 1521 ATGTCCTCGCCCATCTTCCTCTGCCGCCGTCGGTGCTTCTGAATGAG ADAM9 ADXCRPD.11545.C1_at CTCCGCACTGCAACTGCTAAAGTTTCTGGAACACGATGCTCCTGAATTCATGATGCAGCT SEQ ID CTTTGCTCCACAGGAACAATCTCTCCCATCATCGTGATTCATTCCAAGATTATGACCCAA NO: TTCATGAGCAACAATGGAAGCAAATGTCTCCACAGTGATTTGTCCAAACACATTAATCCC 1522 GCCTGCGTGGCTCCTTGAACACACTGTTCCCACAAATGCCATTCCTGCAGTTCCACCCCG ACCTTTCTTTAGAACTAGCTGTGTACTGTCA PTPRK ADXCRPD.10919.C1_at CATAATAGTTCCAAGCTAAAAACAACCCAAATGTCTGTCAGCAGTGCAATGTATAAATAA SEQ ID ATGGTGGCATATTCATAAAGTGAAATATTGTACTGCAAATAAATGAAAGAACCATTGCTT NO: TATACAATAACATGAATGAATTTCGCAAACACAATCTTAAGGGAGAGAAACCAGATGCAA 1525 GAGAGTATGTATATATACATTTATATAAATTATGTAAGTTTCAGAAACAGGCAAAACTAA TCAATGATATTAGAAATCAGCATATTATTTACTTGAAGAGGATTTGGGCAACTT CD44 ADXCRPD.11577.C1_s_at AAACAGCATTGCTTTCTGAAATTAGGGCCCAATTAATAATCAGCAAGAATTTGATCGTTC SEQ ID CAGTTCCCACTTGGAGGCCTTTCATCCCTCGGGTGTGCTATGGATGGCTTCTAACAAAAA NO: CTACACATATGTATTCCTGATCGCCAACCTTT 1527 SPTBN1 ADXCRPD.1922.C1_at TCATATAGCATCTTGGTTAGTTTTTCCTTATCTCTATGTACATATCTATCTACTTCTGAC SEQ ID TGTAGATGGGTATATAGATAGATGCCAAAGCTTCTTATGGTTCTGGGGGTAGTATGCATC NO: ATTTATTGGGGTCTCTGCCTTTAA 1532 SPTBN1 ADXCRPD.1922.C1_s_at GTCAGGATAACGTCATATAGCATCTTGGTTAGTTTTTCCTTATCTCTATGTACATATCTA SEQ ID TCTACTTCTGACTGTAGATGGGTATATAGATAGATGCCAAAGCTTCTTATGGTTCTGGGG NO: GTAGTATGCATCATTTATTGGGGTCTCTGCCTTTAAACACATCAAAATTCATTTTAGACA 1533 RAB31 ADXCRPD.1938.C1_s_at AGCCGCCGGTGCTGTTGACCCAAGGGCCGTGGTCCACGGTACTTGAAGAAGCCAGAGCCC SEQ ID ACATCCTGTGCACTGCTGAAGGACCCTACGCTCGGTGGCCTGGCACCTCACTTTGAGAAG NO: AGTGAGCACACTGGCTTTGCATCCTGGAAGACCTGCAGGGGGCGGGGCAGGAAATGTACC 1535 TGAAAAGGATTTTAGAAAACCCTGGGAAAACCCACCACACCACCACAAAATGGCCTTTAG TGTATGAAATGCACATGGA MAPK1 ADXCRPD.10998.C1_at GAGATATCCGTAGATGGTTTATAGAAATGCATTTGACTTTGGTAAACTGATGAATTACTG SEQ ID GAATAAAAAGATGTCCAACAAACTCTTATTCCAGTAATCCCTCTTTAAATTTTTTAAGGA NO: CAAACATATCATCTGAAAATCATGATATTTTGTTTCTTTTCATGACGTAGATATATTTTA 1537 TCTTGTCTTAACTGTGCTGGCCGGACTCTCCATTACAAAGTTGAAGAGCAGTGGTGATAC AGAGGGCATCCCTGACTTGTTCTGATGTTAAAAGGAAAGCTTTTATTGAGTGATAG AHNAK ADXCRPD.9802.C1_at AACATCAAGGCTCCCAAGATCTCGATGCCTGACGTGGATGTGAACCTGAAGGCCCAAGGT SEQ ID GAAGGGTGATGTGGATGTTTCACTACCTAAGGTGGAAGGTGATATGAAAGTGCCAGAGGT NO: AGACATTAAAGGTCCTGAAGGGAAGCTCAAAGGTCCCAAGTTTAAGATGCCTGATGTACA 1539 TTTCAAAAGCCCACAAAGGCTAAGGTCCACATCTGGATGTGA FLNA ADXCRPD.3227.C1_at TTCACCCTGTCTGGGTGGAAGTCCTGGGGCGCGTCACGGATGTCAGCCATGAAGGGGCTG SEQ ID AGGCGGATGTCTTCGCTGTTGCACAGCACGTGAACGGCATACTCGCCAGCCTCCTGCGGC NO: CAGTAGCGCACATCACAGGAGCCGTCGCCCTTGTCGTCACATTCGATCTTAGCCTGCGAT 1542 GGCCCTTCCACCGAGAAGCCCAGCGTGCCCACGTCGTCCCCGATAGCCTCCACCACAAAG TCTGCTGACTTGCCAACGACG SPTBN1 ADXCRPD.3234.C1_at TCCTTGTTTTCTTGGTTAGTGATTCATTTGCATAAACATTAATGATCTCTGCATACTGGT SEQ ID TTGGGGTTTTCTCTTTCCTTCTAACTCTAAAGAAAAAATTTTTGCTGCAGAATTATCCTC NO: AGAAGAGGCTTCCTGGCCTTCATCTACCCTGCAGTCTGACCAAGTATGATAAATTTTAGC 1543 CGTTTTCAAGGAAACATCTCTCTACCCAGGTCATTGCTGTCACTACAGCTTTCAAGTCAC CACACTAATT SEC61A1 ADXCRPD.3290.C1_s_at CAGCCCACGCTTAGGAATGCTTGGCCTCTGGCAGGCAGGCAGCTGTACCCAAGCTGGTGG SEQ ID GCAGGGGGCTGGAAGGCACCAGGCCTCAGGAGGAGCCCCATAGTCCCGCCTGCAGCCTGT NO: AACCATCGGCTGGGCCCTGCAAGGCCCACACTCACGCCCTGTGGGTGATGGTCACGGTGG 1547 GTGGGTGGGGGCTGACCCCAGCTTCCAGGGGACTGTCACTGTGGACGCCAAAATGGCATA ACTGAGATAAGGTGAA NPC1 ADXCRPD.11658.C1_at GTTCTTACGGGTCTGAGCCTCTGGATGCTCTCTCAGATTTCTGCTGTGGATGAAGGGACT SEQ ID CAGCTGCTCGCTGCAGGTCACCTGACCTCCCTCATGCCGTCACCCATCCACTCTGACGGG NO: TGGGTCATATGCAGAAGCTTCTCAGCACCTGGCCAAGTTGTAGCCGATGGTCTGTCCGAA 1548 AATGCTGGTTCACTCTCCACTGGCCAACTGTCTGTCTGCACTGCACTGCCAGTTGCCTCT TGCCTGCGCCATTGCGCTAACATC VCAN ADXCRPD.2656.C1_at CTTTCCTCACACAATTTGGAATCATATAATATAAGTACTTTGTCCCTGATTAAATAATGT SEQ ID GACGGATAGAATGCATCAAGTGTTTATTATGAAAAGAGTGGGAAAAGGATATAGCTTTTT NO: AACCAAAAGGTGTTTTGCCCCATTCCTAAGAAAATGGAGCGGATTAATATAGAAAAATAA 1549 GTGTGGGGCATTTTCTTTCCCTGGTTAAGGGGGAAAATGGTATGTGGGTTTGAACATTTT TCTTCCCCCAATTGC SVIL ADXCRPD.9920.C1_at GTGAGTCAAGAAGGCCCTCCCCTGTCGGCGTTTGATCTCTCCAGCAGCAAACATCGCACA SEQ ID TGGATTCTTGCAGAGCTTCTCCTGCGGCTGTTCCGAAGAATCCTGGGGCTTCCAGGACAC NO: GGGGGCTGTGGTTTAAGCAATAGTTTTCCCAGCAGCTGTCCCCGTCTGCTCGGAAGTGGG 1551 CTCCCCGAACTCTGCCGCTCTTAGTGAAAACTTCCTTTTCATAACATTCTCCACCTCCAC CTTCTCTTCAAAGGGCAGCCTGTCCTCAAGTC CAPN2 ADXCRPD.9976.C1_at TCGGCTCCGGTGACCGAGTACGCGTGCCCCTTCACCAGCTTCTGAAACGTGAATGGCCTC SEQ ID CGAGTCCCCGGCGCTGGTGATGTCGATGGAGCAGCCAAGGAGAGAGCCTTTTTGCAGAGC NO: TTTCTGGATGATCTTGAACAGGTTGGGAGGGGGCTTCTTCAACTCATACCACTCAGCAAT 1552 GCTCCGGTGAAGTCTTCGAAGCCCTCAGTGGTGGCACCCCCTGATAGTGCTTCATAGCAT CCGTTGATCTTGCGTATGCCTTC COL4A1 ADXCRPD.3378.C1_at CTAAGACTACTAAGGCCTTTTATGTAATTTCTTTAAATGTGTATTTCTTAAGAATTCAAA SEQ ID TTTGTAATAAAACTATTTGTATAAAAATTAAGCTTTTATTAATTTGTTGCTAGTATTGCC NO: ACAGACGCATTAAAAGAAACTTACTGCACAAGCTGCTAATAAATTTGTAAGCTTTGCATA 1553 CCTT COL4A1 ADXCRAD_CN256234_s_at ACCTTAAAGGCCGTCATTTCATTAGTATTCCTCATTCTGCATCCTGGCTTGAAAAACAGC SEQ ID TCTGTTGAATCACAGTATCAGTATTTTCACACGTAAGCACATTCGGGCCATTTCCGTGGT NO: TTCTCATGAGCTGTGTTCACAGACCTCAGCAGGGCATCGCATGGACCGCAGGAGGGCAGA 1554 TTCGGACCACTAGGCCTGAAATGACATT SNAPC1 ADXCRPD.2725.C1_at GAAAGAATCCATCCTTAAAGTCAAAAACTAATGATGGAGAAGAAAAAATGGAAGGAAATA SEQ ID CACAAGAAACGGAGAGATGTGAAAGGGCAGAATCATTAGCGAAAATAAAATCAAAGGCCT NO: TTTCAGTTGTCATACAGGCATCCAAATCAAGAAGGCATCATCAAGTCAAACTCGACTCTT 1555 CGGACTCTGATTCTGCATCTGGTCAAGGCAAGTCAAAGCAACTAGGAAAAAAGAGAAGAA AGAAAGAGTGAAACCAGCAGGAAGGAAGATGTCTCTCTAGAATAATAC SPTBN1 ADXCRPD.2749.C1_s_at AGAGAAGCGGTTCAGCCTTTTTGGCAAAAAGAAATGAACTCCTTTCCTTCACCTCCTGCC SEQ ID CTTCTCTTACCTTTTCAGTGAAATTCCAGCATGCAAGCTCAGAACCAACACATTACTCTC NO: TGTGCCTAATGTTCCTCA 1556 AHNAK ADXCRPD.11792.C1_at TCTGGTCCCTCAATGTCAATGTCTGGCCCACTGACATCCACATGTGGCCCTTTAAGGTCC SEQ ID CCTTCCAATGTGGGAACATCTACATCCACCTCTCCTTTTGCCTTGGGGCTCTTCAAGTGT NO: AGATCGAGGTCTGGCATAGAGATTGTGGGAGCTTTAAAGTGCATATCTGGCATCTGGAAC 1559 TTAGAAGTTTTCCACTTGCCATTTGGGCCTTCCACAGCTACTTCTGGCATGCCAG CORO1C ADXCRPD.2786.C1_at AAGTCTTCCTGTTGTACAGTCATCAAAATGACCAGGTTTGTGCTGCAAAGGAGCCAGCAC SEQ ID CATGTGGCTACTGCTTTGATTGTTCTCAGATGAATGTTTATACAAAATAATATCTTATCT NO: TCATTTAGTTTATAAACATACACAGTGCTGTCCCTTTCAAATTAAGGANAAAAACCACAC 1560 ACACAAATACTGCAAAGTAGCAAAATACAAAGGAAAACAAAGCTACTTTTGGTTTTGGCA ACATTAAAAAAGAAAGAAATATAAAAAGCAATGTGGCATTGGTCCCTATTCAT CALU ADXCRPD.558.C1_at GTAAACCAAGTTTTATATTCTGCAATGCGAACAGGTACCTATCTGTTTCTAAATA SEQ ID NO: 1563 CALU ADXCRAD_CN403921_s_at GATAATTTAATAATGCCACCAACTCTGGCTTAGTTAAGTGAGAGTGTGAACTGTGTGGCA SEQ ID AGAGAGCCTCACACCTCACTAGGTGCAGAGAGCCCAGGCCTTATGTTAAAATCATGCACT NO: TGAAAAGCAAACCTTAATCTGCAAAGACAGCAGCAAGCATTATACGGTCATCTTGAATGA 1564 TCCCTTTGAAATTTTTTTTTTGTTTGTTTGTTTAAATCAAGCCTGAGGCTGGTGAACAGT AGCTACACACCCATATTGTGTGTTCTGTGAATGCTAGCTCTCTTGAATTTGGATATT JAK1 ADXCRPD.4023.C1_at TGCATTTATTCAGCTGTCCAGTGTTCTCCAAGAAGCAAACTGGATTTTCTTCTCTACTTT SEQ ID CCAAAGCTACTTCAGAGAAGCGCACTTCCGTGTGCGCCTGGGCCAGGCAGCGCCCCGTCG NO: CTGCGCTGGCTGGGGTCGACCGGCAGGCTCGCTAGGCGGCCAGCCCCGCGGGGCCCCAGC 1568 GTGCGCGCGCCCAGGGCTGAGGAGGGGTCGCGGCGAGGACAGCCGGGACTGGGCGCAGG MAPK1 ADXCRPD.4057.C1_s_at GAATCTGAATGTTTATTCATTATATTGTTACAATTTAACATTAACATTTATTTGTGGTAT SEQ ID TTGTGATTTGGTTAATCTGTATAAAAATTGTAAGTAGAAAGGTTTATATTTCATCTTAAT NO: TCTTTTGATGTTGTAAACGTACTTTTTAAAAGATGGATTATTTGAATGTTTATGGCACCT 1569 GACTTGTNNNNNNNNNNNCTACAAACAAATCCTCTAGAATCATTAAATTGTGTCCCTGTA TTACCAAA TSPAN4 ADXCRPD.13071.C1_at ACCCTGTTTCTGGAAGGCCCTAGCTCAGGTGGCTTCAGGGCCTCCGGACCCCCCCTGGGA SEQ ID GGGGTGGCCACGTGCTGGCTGCGGAACCCAGGGCAGGGGTGGGAGGGGCCTCCAGCACTT NO: TTTATATTTACGTATTCTCCAAAGCAGTGTTCACACGGGAGCCAGCCTGTGCCCCCAGCC 1570 TCCTGGAAAACAGGTTGGCGCTGGAGGAGCCGGGTCTTGGCATCCTGGAGGTGGCCCCAC TGGTCCTGGTGCTCCAGGCGGGGCCGTGGACCCCTCACCTACATTCCATAGTGGGCCC LAMB1 ADXCRPD.12445.C1_at AAGGCCAAGTGCGTGATCTTTGAGAGGTTTTGGTAGGTAAGAAAGGAGGACTCTATGCAT SEQ ID GTGTGATGGCAGTCGGGGGTGGTAATTTGGGAACACTTCATCTACCTTTGTTCCTTTGTT NO: TGTACTGTTTTCTTAAACCTGTGGAATGTTTTCCCACTTCCCCTGCGCAAATCCCACCAG 1576 CCAACAGCTTCTTCAGCTACAACTGTAGCATTCCTCTGCAGTCTCTCCTTTGTCGACTTT CTTTCATAGTGACTGCATCTGACCTATTCTTGCCCTGC PLAUR ADXCRPD.3441.C1_s_at CAGCCCTACAGACTTGCTGTGTGACCTCAGGCCAGTGTGCCGACCTCTCTGGGCCTCAGT SEQ ID TTTCCCAGCTATGAAAACAGCTATCTCACAAAGTTGTGTGAAGCAGAAGAGAAAAGCTGG NO: AGGAAGGCCGTGGGCCAATGGGAGAGCTCTTGTTATTATTAATATTGTTGCCGCTGTTGT 1578 GTTGTTGTTATTAATTAATATTCATATTATTTATTTTATACTTACATAAAGATTTTGTAC CAG IL6ST ADXCRPD.11859.C1_at AAATGCTTGGCCTAGAAGATGACATGCATGAAGACCCCCCAATACCACTGCTGTGTCCTT SEQ ID CAGTATTAATTTTTTCCTTTTTGAACAGGTCCAATGATTTCAGATCTTCTGGAAAAGGCT NO: TATTGTCATTTGCTTCTATTTCCACAACACTTACATCAGTGAAATTGCCATCTGAATACA 1581 TTTGATCTTCCGAATTAAAATTGTGCCTTGGAGGAGTGTGAGGTGACCACTGGGCAATAT GACTCTTTGAAGGATCTGGAACATTAGGCCAGATGTGTAAACAATTAGGTCTCGCTTAT CRIM1 ADXCRPD.11873.C1_at GTCCCTACTGCATAGAAGACACAATTCCAAAGAAGGTGGTGTGCCACTTCAGTGGGAAGG SEQ ID CCTATGCCGACGAGGAGCGGTGGGACCCTTGACAGCTGCACCCACTGCTACTGCCTGCAG NO: GGCCAGACCCTCTGCTCGACCGTCAGCTGCCCCCCTCTGCCTGTGTTAGCCCATCAACGT 1583 GGAAGGAAGTTGCTGCCCATGCGTCCATGTAAGG CRIM1 ADXCRPD.11873.C1_s_at TGCATTGATAGCGTAATTAGCTGTTTCTCTGAGTCCTGCCCTTCTGCATCCTGTGAAAGA SEQ ID CCTGTCTTGAGAAAAGGCCAGTGATGTCCCTACTGCATAGAAGACACAATTCCAAAGAAG NO: GTGGTGTGCCACTTCAGTGGGAAGGCCTATGCCGACGAGGAGCGGTGGGACCCTTGACAG 1584 CTGCACCCACTGCTACTGCCTGCAGGGCCAGACCCTCTGCTCGACCGTCAGCTGCCCCCC TCTGCCTGTGTTAGCCCATCAACGTGGAAGGAAGTTGCTGCCCA P4HA1 ADXCRPD.653.C1_s_at AGTATTTCACTACATCTCAGTTGGTGGGTGTTAAGCTAGAATGGGCTGTGTGATAGGAAA SEQ ID CAAATGCCTTACAGATGTGCCTAGGTGTTCTGTTTACCTAGTGTCTTACTCTGTTTTCTG NO: GATCTGAAGACTAGTAATAAACTAGGACACTAACTGGGTTCCATGTGATTGCCCTTTCAT 1585 ATGATCTTCTAAGTTGATTTTTTTCCTCCCAAGTCTTTTTTAAAGAAAGTATACTGTATT TTACCAACCCCCTCTCTTTTCTTTTAGCTCCTCTGTGGTGAATTAAACGTACTTGAG AXL ADXCRAD_NM_021913_s_at GTTCTAACCCTATACTGTAGTATTCTTTGGGGTGCCCCTCTCCTTCTTAGCTATCATTGC SEQ ID TTCCTCCTCCCCAACTGTGGGGGTGTGCCCCCTTCAAGCCTGTGCAATGCATTAGGGATG NO: CCTCCTTTCCCGCAGGGGATGGACGATCTCCCACCTTTCGGGCCATGTTGCCCCCGTGAG 1586 CCAATCCCTCACCTTCTGAGTACAGAGTGTGGACTCTGGTGCCTCCAGAGGGGCTCAGGT CACATAAAACTT FNDC3B ADXCRAD_BU665386_s_at ACTACTTCTAATCTAATCACTAGAGTTATTATATTCTGTTATGTTTGACCAGAATTATAT SEQ ID GACAAGAACTGGTGACAGTTTAGTGCCTCTGCCCATTGTCCATGATTTACACTAATTGTG NO: AGCAGTCTTCTTA 1587 PPIC ADXCRPD.13145.C1_at CATTTTATCTGCTATAAGGAGAATTTTGGTAGGGCTAAAAGTGGAAGCAGTCCTTATCAG SEQ ID GAAACCCAAACATTTATAACTTTTGGGAATTTCTCACTCCTGGGACTGGCTTTAGAAAGT NO: GATCCAAAATTGTAAGGGGAGATCATCAGTGTTTTGGTCAGCCTGGCAATTTAGTCCACT 1590 TGCTCTGGTGATGGCTGCCCAATTTCTTATTTTTCTTTTGAGAAATCACATCCTTCCCTC ACCCATCTCTAGTCCTTAGGGTGGGCTGACTCTACAGGATGGGTAC FLNB ADXCRPD.13162.C1_s_at AAGGACGGCACGGTCACTGTTAGATATGCCCCCACTGAGGTCGGGCTCCATGAGATGCAC SEQ ID ATCAAATACATGGGCAGCCACATCCCTGAGAGCCCACTCCAGTTCTACGTGAACTACCCC NO: AACAGTGGAAGTGTTTCTGCATACGGTCCAGGCCTCGTGTATGGAGTGGCCAACAAAACT 1591 GCCACCTTCACCATCGTCACAGAGGATGCAGGAGAAGGTGGTCTGGACTTGGCTATTGAG GGCCCCTCAAAA CCND1 ADXCRPD.3501.C1_s_at TCTGTCTGAACCACGCGGGGGCCTTGAGGGACGCTTTGTCTGTCGTGATGGGGCAAGGGC SEQ ID ACAAGTCCTGGATGTTGTGTGTATCGAGAGGCCAAAGGCTGGTGGCAAGTGCACGGGGCA NO: CAGCGGAGTCTGTCCTGTGACGCGCAAGTCTGAGGGTCTGGGCGGCG 1592 CCND1 ADXCRAD_BM551840_x_at TGAGGGACGCTTTGTCTGTCGTGATGGGGCAAGGGCACAAGTCCTGGATGTTGTGTGTAT SEQ ID CGAGAGGCCAAAGGCTGGTGGCAAGTGCACGGNGCACAGCGGAGTCTGTCCTGTGACGCG NO: CAAGTCTGAGGGTCTGGGCGGCGGGCGGCTGGGTCTGTGCATTTCTGGTTGCACCGCGGC 1593 GCTTCCCAGCACCAACATGTAACCGGCATG FTH1 ADXCRPD.13188.C1_at AAGTGCAGGGTCAGTACTCCAGCGCCCTCTCATCAGACAATGAATTCTGACACTGGCTGT SEQ ID AAGTTTTCTGTGCAGTAATACAGATCCTTAAGACATTGCCCCAGGCAATGCCCATAATAT NO: CCTAAAGGTTCCTTGAAGTTAAGTTTCAAGGATCAAGTTTCAGTTTTCTATTTTAGAATA 1594 GAAACATTACTCTTGGGTTCAATCCAGTAGCTCATCTGCCCCCCAGTCTCCTTAGGCACT GATTCCTTCATGCTGTGCTTTGA PTPRK ADXCRPD.13194.C1_at ATCACATGAATATATCTGCCTGACAAAAATTTGGGAAGTCCAGCATCTCTGATTTAAAAA SEQ ID GAAGAAACTATTTGTAATTTTAGTCTCTTGTTCTTAATGCAGGATCTGACCATTGGTTAG NO: TAATGCAACAGCTGCGATTAGCAATGAAGGAAAACTATTTTCAGAGTCTTCTCATGACCT 1595 AGCCACATTAGCAATCTAAAAATACAAACAGGAAAAGTTTTTAAAAGCTTAACCTTTTAT AAAGTGACTAAACTGCATAAGCCATCAGCCACAGA PTPRK ADXCRPD.13198.C1_at CACCGGAGGTAGTTGATAGATCGAGAATACACAAGGACACTCACAGTCACACATAGAACC SEQ ID TAGAAACAACACTCCCCAAAACAGATGTAGATTCAACAAAATACTATAAAAAGCCATAAA NO: GCATATTCAGTATATAATGTTTAAATTGTTCTGACATATATGTTGTTTGTATACCCGCAC 1596 AAATGTTACTGTCATTAAACTAATGATCCTATTTTCTTCTTCTCAAAAAAAGTCCTAGAA ATCTGTTTGTGATGGCTTGATGAAGTTTAGTCACTTTATAAAAGCCACCTTGG KDELR3 ADXCRPD.3569.C1_at TACTTAGGCGAGTACCATTTGCACAATCACTGTTTTACTTATGAGCAGATACAGATATAT SEQ ID CCAAACCCTTACCTACTAGGTATCCTGCTAGGGTTTTCAATTCCAATTCTTGTATTAAGT NO: TTTTTCCTTTCAGTTTTAGGTGCGAAAGTAATCAGTCAATCCAATATCCCCCATCTTTGT 1599 CTTGAAACAAAAACTGTTTTAAGACGTCTACGTTGAATTATTCAGAGAATTAAGCAATAA AAGCTCACACCTTAT VEGFA ADXCRPD.3590.C1_s_at GATTCTGATAAAATAGACATTGCTATTCTGTTTTTTATATGTAAAAACAAAACAAGAAAA SEQ ID AATAGAGAATTCTACATACTAAATCTCTCTCCTTTTTTAATTTTAATATTTGTTATCATT NO: TATTTATTGGTGCTACTGTTTATCCGTAATAATTGTGGGGAAAAGATATTAACATCACGT 1601 CTTTGTCTCTAGTGCAGTTTTTCGAGATATTCCGTAGTACATAT CORO1C ADXCRPD.2994.C1_s_at GAACATTCTGGATAGCAAGCCCACTGCAAACAAGAAGTGCGACCTGATCAGCATCCCCAA SEQ ID GAAAACCACAGACACGGCCAGTGTGCAAAATGAAGCCAAGTTGGATGAGATTTTAAAAGA NO: GATCAAATCTATAAAAGACACAATCTGCAATCAAGATGAGCCGTATTTCCAAGTTAGAAC 1604 AAGCAGATGGCAAAGATAGCAGCCTGAAGGTCCCACC KIF2C ADXCRPD.737.C1_s_at AGCATCCTGCCTGCGTGGACTGGCTGCTAATGGAGAGCTCCCTGGGGTTGTCCTGGCTCT SEQ ID GGGGAGAGAGACGGAGCCTTTAGTACAGCTATCTGCTGGCTCTAAACCTTCTACGCCTTT NO: GGGCCGAGCACTGAATGTCTTGTACTTTAA 1607 TGFBR2 ADXCRPD.4225.C1_s_at AAAGACCAAGGAATAACATTCTGTAGTTCCTAAAAATACTGACTTTTTTCACTACTATAC SEQ ID ATAAAGGGAAAGTTTTATTCTTTTATGGAACACTTCAGCTGTAC NO: 1610 EPAS1 ADXCRPD.4267.C1_s_at TGCACGGCATTACCCCACACAGGGTGGCAGAACTTGAAGGGTTACTGACGTGTAAATGCT SEQ ID GGTATTTGATTTCCTGTGTGTGTTGCCCTGGCATTAAGGGCATTTTACCCTTGCAGTTTT NO: ACTAAAACACTGAAAAATATTCCAAGCTTCATATTAACCCTACCTGTCAACGTAACGATT 1611 TCATGAACGTTATTATATTGTCGAATTCCTACTGACAACATTATAACTGTATGGGAGCTT AACTTTATA SYNJ2 ADXCRPD.4271.C1_s_at TTACTGTACCGCCTGTTGTATCTGGGAGCCTCGTACAGAGGCTCGCACAGCAGTGATCAA SEQ ID GTGTCATCCCTTACGTGACTGGGGGATGTCTGTCCTAAAAGCTGACTGCTAGGATAGTAA NO: GGATCATCTTGCCTGGGCTATGCCACTGTCTTGTTACCAATTAGACATCTGGAATTTCAT 1612 AATTAGTTTTCATTGTCACTGTCAAG JAK1 ADXCRPD.3619.C1_at CAGTTGTTGAAGTGTAGCAGCAGCTTTTTGCAGGGAAAGAGGGAGTTGTATTTATTGCTT SEQ ID CTCCATGACATGGTTCTTTTCTCATTAGTTCATGGGCAAGTCAAGGGAAAGAGACCTAGG NO: TAGCAGCTGAGTCTGTAGCCTACAGATGGCCTGGGCTGGCTTGGCTCAGTCACTTCCCTT 1613 AGTCACTTCCACACATTCCAGAAATT PHACTR2 ADXCRPD.12664.C1_at TTATACCAAGATCAAACAAAGCCATGATTTCTGTTTCACTCTGCATTGGGCTAATTGATG SEQ ID TTTGGACAGTTCAATTCTGATAACAGCAGCGCACACTCTAATTCTCTCTGGGAAGTGAAG NO: GAAACACTGCCCTGTATTTTCCTGACTTCAGGCTTATACTCTGGCAATCTTCCAAAAACT 1614 TCCCATGGCTGCCCATCTTACTTCCAACAATCCCTGAAC PPP4R1 ADXCRPD.4310.C1_s_at ATACCTTGAGGGAAGTCTGCGATGATGAAAGAGATTGTATTGCTGTTTTGGAAAGAATTA SEQ ID GCAGATTGGCCGATGATTCAGAACCAACTGTGAGAGCGGAGCTGATGGAACAGGTGCCTC NO: ACATCGCACTGTTTTGTCAAGAAAACCGGCCTTCAATACCATATGCTTTTTCAAAATTCT 1620 TACTACCTATTGTGGTTAGATACCTTGCAGATCAGAATAATCAGGTGAGGAAAACAAGTC AGGCAGCTTTGCTGGCTCTGTTGGAGCAGGAGCTCATTGAACGATTTGA FLNA ADXCRPD.13338.C1_at GGTAGGCGTCAATGTCACTTACTGGAGGGGATCCCAGCCCTAAGAGCCCTTTCTCAGTGG SEQ ID CAGTATCTCCAAGCCTGGACCTCAGCAAGATCAAGGTGTCTGGCCTGGGAGAGAAGGTGG NO: ACGTTGGCAAAGACCAGGAGTTCACAGTCACAATCAAAGGGTGCTGGTGGTACAAGGCAA 1621 AGTGGCATCCAAGTATTGTGGGCCCCTCGGGTGCAGCGGTGCCCTGCAAGGTGGAGCCAG GCCTGGGGGCTGACAACAGTGTGGTGCGCTTCCTGCCCCGTGAGGAAGGGCCCTATGA CTSA ADXCRPD.13357.C1_at GGGATAGCAAAGATAGATCACTAACAGCGATAGGACCCCAGAGTAGCACAGCAAGCTGGG SEQ ID GGCCCTATGAGACTTCCTGTCAGGACAAGGGAAGCTGAAACTCCGAAAGGCGAAGCCCAG NO: GGTCCTGTGATTGGTGGGGTCAGAATTTGAACCTGGGTTTGTCCCCACCCATGCTGTCCT 1625 GCTATAGGAGGCCTAGGGGTCTGCATCAGCCACGGAGTCTTAAGGGTGAGAAGAGCTTCA TTCATGCCAAAAATGGGCCAGCAGAT ZDHHC7 ADXCRPD.12706.C1_at TTGGTCCGGAGCCACCTGCGGACAAGCGTTCTGCCTGGGTCTTGGCTCTTGGCGTTTCTT SEQ ID TGCAGCTCCATCTCTCCGAGTGCTCCCATCTGATACACGTTTCAAAAGTTCAATTCCAGG NO: GTAGCCAAAAGTGTGAAGCTGCCATGGAGAAGGGCTAAAAAACAACCAGGAACCAAGCAA 1626 CCACT ADAMTS1 ADXCRPD.13363.C1_at TATGATGCGATCACAACCAGCTTTTACACACTGTCCTTGCACACAGACAGAGGTGGAATC SEQ ID TGGGCTACATGGAGTACCATCTACAACCTTGGGCTGCAAAACGAAGAAGTAGCCAATGCC NO: TTTGGCTTGGCAGATGAGCTTGCACCTGTCCTTTGGTGAGACGCCAGCGTACTTGGGAAT 1627 CCATTCCACCGCAGGCCCACTCCCAAAGGAAGCTTTTGAAAACTCGTTGTGTGCTTCACA TT PMP22 ADXCRPD.5015.C1_s_at AAATCATAAAGCCTTCATCACTCCCACATTTTTCTTACGGTCGGAGCATCAGAACAAGCG SEQ ID TCTAGACTCCTTGGGACCGTGAGTTCCTAGAGCTTGGCTGGGTCTAGGCTGTTCTGTGCC NO: TCCAAGGACTGTCTGGCAATGACTTGTATTGGCCACCAACTGTAGATGTATATATGGTGC 1634 CCTTCTGATGCTAAGACTCCAGACCTTTTGT KCMF1 ADXCRPD.14034.C1_at ATTGCCAAGTGGAGATAAAGGTGTCCATTTGGGTAGGGTCAGGAAGCTGTGGTATTCATG SEQ ID CCTCATGGCCTTTCATTTTCTTAGAGCCGTAGGGGTAAAATCATGCCATTTTTTGCCTCT NO: GTGCCTCATAAGTTTGTACTCCTTCCTCCTTTAAAAATCAGCTGTAAGAGCTGGATGTGC 1635 TGTA SPTBN1 ADXCRPD.13403.C1_at GGGCAGACAGGAGGGCATCCTTCTTCCTGTCAACCAGTTCTCTGAACTGGCTCCACCTTG SEQ ID TGTTGAGTTTGTCCTGCTGGGCTTTGATTTCCTTCTCACTTGGGTGGCCGCTGTGCATCA NO: GCTGGCGTGCCATCTGGTTCACCACTGCAACCCGGGAAGCCTGGTTGTTCATTTCTGGTT 1639 CTACGGCTCTCAATCTGTGCTGGATGTACCTCCACGATCCTCCAGCTTCTCTGGGATCTG CATGTTGTTGAGCCACTGCTCCTTCTCGTCGATCCAGAGCTCACGGCATAGC PPAP2B ADXCRPD.13412.C1_s_at ATGTTCTGGCAGGATTTGCTCAAGGAGCCCTGGTGGCCTGCTGCATAGTTTTCTTCGTGT SEQ ID CTGACCTCTTCAAGACTAAGACGACGCTCTCCCTGCCTGCCCCTGCTATCCGGAAGGAAA NO: TCCTTTCACCTGTGGACATTATTGACAGGAACAATCACCACAACATGATGTAGGTGCCAC 1641 CCACCTCCTGAGCTGTTTTTGTAAAATGACTGCTGACAGCAAGTTCTTGCTGCTCTCCAA TCTCATCAGACAGTA PTPRK ADXCRPD.14082.C1_at ACTAATATGTTCAAAGTGCCAGGATTCAGTCCTTTCTGGCTATATAATAGGTAACTGAAA SEQ ID TCAATGCAGTGAGTGTCGTTCTCCTTCATTGTAGGCAGCTGAAGTCTGGCTTTTTCTCCA NO: GGGTCGTGATCTGAAGAGTCCACTATCATATAGGAACCTTGGGGCATCTCGGGTGGTAGA 1647 TAATGAGGCTCTTGAGCACTAACATGCACCCATTCAAAGTCATCATACAGATCCTGGTGG TAATCACAGGCCCCTGGAC MARCKS ADXCRPD.4423.C1_at TTCAACAAAGAAACTCAACAGATCCAAGAGGGGAAACAAAGAGCCTCGGGTTGGTGTAAC SEQ ID GACGGGGCGAGCAGCAGCAGCAGCGGCGGCCAACAGCGGCAGCCTACAGCACACCGGAGG NO: AAGGGGGGTGGGGGTGGTGGAGAGGACAGAACAGAACCGATTAAATACACTCCGGATAAA 1648 AAAATTTTAGTCGAAGAGATCAAAAAGCAGCAGCACAGGAGGGAGGGAAAAAGGGTGGAA AAGTCGAGCACCAAAAAAGGAGCCCCAGT MARCKS ADXCRPD.4423.C1_x_at CCCATGCTGGCTTCTTCAACAAAGAAACTCAACAGATCCAAGAGGGGAAACAAAGAGCCT SEQ ID CGGGTTGGTGTAACGACGGGGCGAGCAGCAGCAGCAGCGGCGGCCAACAGCGGCAGCCTA NO: CAGCACACCGGAGGAAGGGGGGTGGGGGTGGTGGAGAGGACAGAACAGAACCGATTAAAT 1649 ACACTCCGGATAAAAAAATTTTAGTCGAAGAGATCAAAAAGCAGCAGCACAGGAGGGAGG GAAAAAGGGTGGAAAAGTCGAGCACCAAAAAAGGAGCCCCAGT ARID5B ADXCRPD.12803.C1_at GATTCTCTAGTATGTAGGACAGTTTCACAGCCTAGATAAGGTAAGTACAATGCTCAATAT SEQ ID TTTCACAGAACCCAATACTTCAAAGCAAAGCATTTGGCTGGGTAAGCAGTGTATAAGCTC NO: TTTCAACTATGCCATTTATGAGGAACAAAATCCTTAAGTTGCGGATCTACAAAGGAACGT 1652 TCTTTGCACTATTGTGTGCTTGACTGTTTCTTTTTCATTTGTTCCACTAGAATCAGTTAG CTTCAATGTGTAACAACACGCGCG COL5A2 ADXCRPD.12854.C1_at ATGTGCACGTCTTGCTCACGAGCAGTTCTATTATACATTTAGCTAACAAGTAAACAGCAT SEQ ID ATATTACATCATCAACTTGGTGATATAATAAGAAATACTACAGAATTAAAAAACATAATG NO: TGGATCAAATCATCCTTGCTTAAATACATCAAGAACTTCCCAACTACTTAA 1654 COL5A2 ADXCRPD.3875.C1_s_at GGGACCATCCCAAAAGACAAGCCATGCATACAACTTTGGTCATGTATCTCTGCAAAGCAT SEQ ID CAAATTAAATGCACGCTTTTGTCA NO: 1656 FNDC3B ADXCRPD.14126.C1_at ACCATGGCAACGAGGTAGTCTGTTCTATTTTTGGAGTATGAAAGTAGTGCCTTCTTAAAT SEQ ID CTAATAATAAATGAGAGTTCCAGAAAACCAGTGCTTCAAACAAATTTGATTTA NO: 1658 TFE3 ADXCRPD.14170.C1_at CCTTTTGAAGGCACGGCAGAACGAAAGACATCAACAACCTTAATTTGAGCGTCGCAAGGC SEQ ID GATTCCAACATTTACCGACAGGAATCAGGGAACTGGGGCCTCCTCATCCTAGTCCAGTGA NO: CCGGAGA 1660 ID3 ADXCRPD.4520.C1_s_at CCCAAGTTCTAAGGTCTTTTCAGAGCGTGGAGGTGTGGAAGGAGTGGCTGCTCTCCAAAC SEQ ID TATGCCAAGGCGGCGGCAGAGCTGGTCTTCTGGTCTCCTTGGAGAAAGGTTCTGTTGCCC NO: TGATTTATGAACTCTATAATAGAGTATATAGGTTTTGTACCTTTTTTACAGGAAGGTGAC 1661 TTTCTGTAACAATGCGATGTATATTAAACTTT SGCE ADXCRPD.12912.C1_at GTTGGATGTCTGGTGTATGCATGTAATCTCTTTTCCACGCCTTCCCGTCGGCAGCACATG SEQ ID ATATAAAGCAAGTATTAGACAAAAGGACCAGTTGCCACTGCCGAGGGCACAGCCAGTGTA NO: ATCAGGAACTCCGTGTAATAGTCTCTGCTTTTCAAAGAATCAGAAGGGGGTTAGTATTCT 1663 CCCACCATCAGGTAAAATCCCCTCTCCAGGAATTACTTCTTGATAGTGGACCCTTGCTTG TTTATCACCAATG FNDC3B ADXCRPD.13581.C1_at CCGGATTAGAAGCAGTCAGCCTGAATGTATACTGTGTGCTTCTTTTGAGATTTTTCACAG SEQ ID TACAGGTTAAATCCTCTCCAGTGTATTTTGGGTGGAAAAGGTTATCATTTTCATCCTCCT NO: GAATTTCCAAGGTGTAGGTGATCACTTCCTCGGGTGAACAGCCTTCTGGCTTACTCCACT 1667 GCAACGTGACCCATGTGATGCCAGCTCGAACCAGCCTTGGTGCAGAAGGCATCTGAGGGA TATTTCCTAATGTGTAGCACACCACCTCTTGGCTATAACCACTGGTACCAATGTCGTTTC KCMF1 ADXCRPD.13587.C1_at GATGGATATCTTTGTCAGTACATATAATTCTATTTGGTTCTCTTTAATGGTCACATAGTA SEQ ID AGACTTATTATATTAGGGTCAGCAAAGTATGGCCTCTAGACCAAATATGG NO: 1669 LMNA ADXCRPD.3925.C1_s_at TTGAGCTGCCTTCCCTAGCTTTAGACCCTGGGTGGGCTCTGTGCAGTCACTGGAGGTTGA SEQ ID AGCCAAGTGGGGTGCTGGGAGGAGGGAGAGGGAGGTCACTGGAAAGGGGAGAGCCTGCTG NO: GCACCCACCGTGGAGGAGGAAGGCAAGAGGGGGTGGAGGGGTGTGGCAGTGGTTTTGGCA 1671 AACGCTAAAGAGCCCTTGCCTCCCCATTTCCCATCTGCACCCCTTCTCTCCTCCCCAAAT CAATACACTAGTTGTTTCTACCCCTGGC MARCKS ADXCRPD.3926.C1_at AATCCTCCCGTCTCTCCAAAACCATCTCCCCGTCCCCTGACATTGCGGCGCTCTGANNNN SEQ ID NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NO: NNNNNNNNNNNGAGAGAGCTTTTTGGCGCGCGCCTTTCCCCTGGCGCTTTTCTCCCCGGG 1672 AGGATTGTTCTCCACTTTTCGCCCGTCATAGCCTAAATCCG LOXL2 ADXCRPD.4590.C1_at GGGTTGCTCTGGCTTGTACGCTTTCCGGAATCTCGAGGGTCCGTCAGGGCTGAAGACCTG SEQ ID CCCAGGCACACAACTCACCACGGCCGGTAGCCCATTCTCGCAGGTGACATTCTTCATGGG NO: GTCCAGTGACACCTGGGGGCCCAGCTTGCAGCTGGAGATGTGGGCCTCTGTGCCGGTGCA 1674 GTCCATGGAGAATGGCCAGTAGCGCTGCTTCCTCCGTGAAGCACACATTTTGTACACTTT YWHAZ ADXCRPD.12994.C1_at AAAATCTCCCTTCCAATGCCAGGAAATCTCCTCTAACATAATGAATTTCCCACCCCACCA SEQ ID CTATCCCTTACATTTCTTTAAATTCAAGATCACTTTTCTTCTTAAAAAGTAATCAGAGAA NO: TTTATAAACTAAGGGTCCTTAGACCAAACCCCAAAATTATGAACAAGAACTCAATCATTA 1678 AGTATTTGTACATTCACCTCAGTCCTGAAGAATAGCCAACCTGCCACTATACACTCAAAC CACCGTGCTATGTGCTGAGATTTGGGCTTGCCAACCATCTCCGGGAT CCND1 ADXCRPD.3980.C1_s_at GGAGGTGGACCTGGCTTGCACACCCACCGACGTGCGGGACGTGGACATCTGAGGGCGCCA SEQ ID GGCAGGCGGGCGCCACCGCCACCCGCAGCGAGGGCGGAGCCGGCCCCAGGTGCTCCCCTG NO: ACAGTCCCTCCTCTCCGGAGCATTTTGATACCAGAAGGGAAAGCTTCATTCTCCTTGTTG 1679 TTGGTTGTTTTTTCCTTTGCTCTTTCCCCCTTCCATCTCTGACTTAAGCAAAAGA SERPINH1 ADXCRPD.5216.C1_x_at AAACTAGGTGCTGCAGCCCCTGGGACCAGGCACCCCCAGAATGACCTGGCCGCAGTGAGG SEQ ID CGGATTGAGAAGGAGCTCCCAGGAGGGGCTTCTGGGCAGACTCTGGTCAAGAAGCATCGT NO: GTCTGGCGTTGTGGGGATGAACTTTTTGTTTTGTTTCTTCCTTTTTTAGTTCTTCAAAGA 1680 TAGGGAGGGAAGGGGGAACATGAGCCTTTGTTGCTATCAATCCAAGAACTTATTTGTACA NNNNNNNNNNCAATAAAACTTTTCCCACCCCCCTCACACCTCTTCTCCCTAGAATA NT5E ADXCRPD.5241.C1_at CACAGAGTTCTTGAAACCCACGATTCTTCTTCAAATCCAGATGTGTGTGAGCCCCACCTC SEQ ID ATCAACTCTGAAGGCTGAAGGATCAGCTGGAATTTCTGCTGCAGGGTGTCCCTGATAAGC NO: TCAAAAGCATCAGAACGGAGGGAGCTTTCTCCCCTTCTCTCATCTCATTAAAATGAGCTT 1683 TCTTGTTGTGGGGGGTTGGGGAGGGACCTTTAAAACCAAACAATGGTGCCCTCTTATCAT CTTTTNCTGTCCTCCTTTCTCCAAGTTTCCAGAGGG PEA15 ADXCRPD.14289.C1_at AAATCAGCACATTCCTCCTACTTCCCTTTCCTCCACTCCCCCCATATCTTTAAAGTGTGG SEQ ID AAGCAGAAAGGACCTGCATTTTCCTACATTGAGGAGCTGACATAGGGGTAAGGTATGGGA NO: GAGGTAGGTGGATCCAGGGAAAA 1684 PEA15 ADXCRPD.14289.C1_s_at AAAAGCCAGAGTTCCATGTTTGTACTCCTTGTGCTGGACTGTTTCCTGAGTACCAGCAGG SEQ ID TCCCTTTTTGTCTC NO: 1685 PEA15 ADXCRPD.14289.C1_x_at AAATCAGCACATTCCTCCTACTTCCCTTTCCTCCACTCCCCCCATATCTTTAAAGTGTGG SEQ ID AAGCAGAAAGGACCTGCATTTTCCTACATTGAGGAGCTGACATAGGGGTAAGGTATGGGA NO: GAGGTAGGTGGATCCAGGGAAAAGCAGTGGGGACGGAAGGCAAGAGACCACTCAACCCCC 1686 ACCTGGAAGGGGCAAAGAAAAGCCAGAGTTCCATGTTTGTACTCCTTGTGCTGGACTGTT TCCTGAGTACCAGCAGGTCCCTTTTTGT IL6ST ADXCRPD.13648.C1_at GATAGACCATCTAAAGCACCAAGTTTCTGGTATAAAATAGATCCATCCCATACTCAAGGC SEQ ID TACAGAACTGTACAACTCGTGTGGGAGACATTGCCTCCTTT NO: 1687 IL6ST ADXCRPD.13648.C1_x_at ATATGTGTATAGGATTCGCTGTATGAAGGAAGATGGTAAGGGATACTGGAGTGACTGGAG SEQ ID TGAAGAAGCAAGTGGGATCACCTATGAAGATAGACCATCTAAAGCACCAAGTTTCTGGTA NO: TAAAATAGATCCATCCCATACTCAAGGCTACAGAACTGTACAACTCGTGTGGGAGACATT 1688 GCCTCCTTTTGAAGCCAAT GJA1 ADXCRPD.13657.C1_at TTTTAGAATTCTGGTTATCATCGGGGAAATCAAAAGGCTGTGCATGGGAGTTAGAGATGG SEQ ID TGCTTCCCGCCTGCCCCATTCGATTTTGTTCTGCACTGTAATTAGCCCAGTTTTGCTCAC NO: TTGCTTGCTTGTTGTAATTGCGGCAAGAAGAATTGTTTCTGTCGCCAGTAACCAGCTTGT 1689 ACCCAGGAGGAGACATAGGCGAGAGGGGAGCGGTTGGTGAGGAGCAGCCATTGAAATAAG CATATTTTTGAGACCCACAGTCTTTGGCAGGGCTCAGCGCA CD59 ADXCRPD.5301.C1_s_at AACCCACTGGTGCAAGTCCTAGATTCCAAAGGCTGAAGAACCTGGAGTCTGATGTCCAAG SEQ ID AGCAGGAAGAGTGGAAGAAAGCCAGAAGACTCAGCAAACAAGGTAGACAGTGTCTACCAC NO: CACAGTGGCCATACCAAAGAGGCTACCGATTCCTTCCTGCTACCTGGATCCCTGAAGTTG 1692 CCCTGGTCTCTGCACCTTCTAAACCTAGTTCTTAAGAGCTTTCCATTACATGAGCTGTCT CAAAGCCCTCCAATAAA LPP ADXCRPD.5328.C1_s_at GAGCTATAGTACATGTGTGTTATGAATGAAATATGACAGCATGTTCCATACCCCTGCTTT SEQ ID AGCCATCTGTGGGAAACCAGCAAACTGAAAAAGACACCTCTGCAAAATGTGCCTCAAGTC NO: CATTTCTTGGGATCGCTCGTTTGGTGCACTCTCGTGGGAGACAATCAGAGAACAACATAT 1693 ACTTGTGCCTTATTTTCA KCMF1 ADXCRPD.14355.C1_at GGATAACTGCTCTATATGTGGAGAACATTAGAACAAAGGGACCTGAAGTTATATTTCAGT SEQ ID GTCTTAGCGAGGATTTCAGGAACTGCTTGGTATGAAGAGTTGTGTCAGGGTGAGTCTGTT NO: GTACTTCCCCAGCTAGAACAAGTCATCTTTCATCATTTTCATATGTTTGGCTTTGTTTCT 1695 GTAGGTCTCTATCCCTTAGTCTTCATACTGTTTTAAATGCTTATTTACTTATCCTTATTC CCCATTTAGGCTCTAAGCACTAAGTGGGTACTGCAAGTGCTCAAAAATTTTG CDC42BPA ADXCRPD.15053.C1_at TGTACTCCAGCTAGCACAGGCAGACGTGTAAGAGACTTTTGCACTTTATGTACCCATCCT SEQ ID GAGGC NO: 1699 CDC42BPA ADXCRPD.15053.C1_x_at TGTACTCCAGCTAGCACAGGCAGACGTGTAAGAGACTTTTGCACTTTATGTACCCATCCT SEQ ID GAGGCCTTTTCCCCTCTCTCATCCTTTTGCCATGTCCTGTGGT NO: 1700 SPTBN1 ADXCRPD.15064.C1_at GGTATTCCCAGAGCCGGATGACATTGTCCTTCCTCGCTGTGATGCGCTTGATGTCGTGGT SEQ ID AATTATCGGCCTCGAGCTAACTGGCCACGGCTACCACAGCCTGCACACGCTCCTCGTATG NO: CGGCAATGTCTGTCTCAATGGCCTCGTGCTTTTTTGTGGCGGACTCAACTGCAGGAAGGT 1701 CAAACCCAAAGTTGTCCTGAGACACCAGACGCTGCTTTTCGCTCAGCCAAGTCTCCCTCA TAGCTGCATTGCGATCAAATCTGCGGGCGAGCTGTTCCAGT TGFBR2 ADXCRPD.13821.C1_at TTTGTGTCCCACATTCAAATCCTCTCTAGTAATTTCTGCAAAGGTTGAGAAGGCTGGCAT SEQ ID GATGGAGAGAACGGTAACCATGAGGAAAGCTTCTTGGAGTAAAGCACTCCTCTCTCCAAT NO: GCAGAGGGTAAAACTATTAACATATAAGCAAAAGAAACTTGGGCTAACTGAGACCCTTAA 1706 AGGAGTTCCCCTTTAGTCCAATAAAAGGCCAACTTCAAATCTTTACACCAGATAAGGTAG TCAAGATCATATCATATACCCAGAGAATGACTGCTTGTATGGACATTTCCTAC IL6ST ADXCRPD.14481.C1_s_at TGTTTACTAACATATATTGACCAAGTACATCAAGCAGGAGAGATCTTCCTTCATTCTGTT SEQ ID ATAGTCCACATCATTCTAATTTTGCTCAGTTGTTATTAAGAGCATATTCCTAAACCATAC NO: ACTTTTGTTTCAATAAAGTTTTATTTTGTTGAGATGAATAAAATAACAAAGTTATAAGCT 1707 GCATAAGACAAAAGTTCAATT FAM50A ADXCRPD.13832.C1_s_at AATCCAACATTGACAAGAAGTTCTCTGCGCACTACGACGCGGTGGAGGCAGAGCTCAAGT SEQ ID CCAGCACCGTGGGTCTCGTGACCCTGAATGA NO: 1708 FLNB ADXCRPD.13858.C1_s_at ATGCTGTTCGCTTCATCCCTCATGAGAATGGTGTCCACACCATCGATGTCAAGTTCAATG SEQ ID GGAGCCACGTGGTTGGAAGCCCCTTCAAAGTGCGCGTTGGGGAGCCTGGACAAGCGGGGA NO: ACCCTGCCCTGGTGTCCGCCTATGGCACGGGA 1710 HSBP1 ADXCRPD.4853.C1_at CAACTACAGAACCTCCTTTGATCAGGCCAGTAGGTTGTGATGCAGGCTGGAGCCCCCGAA SEQ ID TGCCCCACACACACTGCAGCATTGACCAGACCATCCGAAACCTGCGTCCCTGGTGATGTT NO: CTCAAGCCTCGGAAGTGGCAAATGGAAATGATATGGCCGGTTGCGGTTGTAGGAGAGTTG 1713 TGACTTAGGCAGGAGTCGACCTCCTCAAGTAATGGAACGATTTCAAAGGCAGGCTGCCCT GACCAAAAATATCTGCCATGAATAAAGGTGCCTGAAATCCTGCTATGAA TGFBR2 ADXCRPD.13873.C1_s_at AAACATCAAATATTCCCAGGAAATTGGTTTTATTGGAGAACTCCAGAACCAAGCAGAGAA SEQ ID GGAAGGGACCCATGACAGCATTAGCATTTGACAATCACACATGCAGTGGTTCTCTGACTG NO: TAAAAC 1714 KCMF1 ADXCRPD.14509.C1_at AGCATTGACAGCAATACTGCTTGTGGTATCTGAACTTCAATACAACATGTCTGTTATGGA SEQ ID CTTGCATTTGAAGCCATCACATTTATAGAGTATCTGACTTCTTCATTACTTCTTTAAATA NO: ACTTCCTAAGCATCTGTATCTTGAAAGGCATATTATCACATATTGTTTTCATTTGTCCTT 1717 TACATTTGAGCATTTTAC CDC14B ADXCRPD.5520.C1_at ACTCCTCCGCGGAAGCATGGAGGGAAAGGAGGTTGTAAAATAGACTCCATGGAGACTCTT SEQ ID AGGAAGCAGTAGATTCCCGGGGGCTGTGCCTTTAGCGTTAGAGGAAACACATAGAGCTGG NO: AACTGTTAATGGAAAGCAGTCACAGCTGAGTTTTCCGAGACCAAGAAATTA 1718 CDC14B ADXCRPD.5520.C1_x_at TCGAGAGCAGGCCATTTCCCAAGAAGATGAAGAATGGTGACTGTGTTTTTATTGAAGGAA SEQ ID TTTCAAATGAAGAATAATGTTTAAAATGTGTATATAGAGATAGTATAGACTCCTCCGCGG NO: AAGCATGGAGGGAAAGGAGGTTGTAAAATAGACTCCATGGAGACTCTTAGGAAGCAGTAG 1719 ATTCCCGGGGGCTGTGCCTTTAGCGTTAGAGGAAACACATAGAGCTGGAACTGTTAATGG AAAGCAGTCACAGCTGAGTTTTCCGAGACCAAGAAATTA CCND1 ADXCRPD.13939.C_1_at TTCACATTGTTTGCTGCTATGTGGAGGATCAGTGTTTTGTGTTACAATGTCATATACTGC SEQ ID CATGTACTAGTTTTAGTTTTCTCTTAGAACATTGTATTACAGATGCCNNNNNNNNNNNNN NO: NNNNNNNNNNNATGTGATCAATTTTGACTTAATGTGATTACTGCTCTATTCCAAAAAGGT 1727 TGCTGTTTCACAATACCTCATGCTTC CASK ADXCRPD.4921.C1_at GGGAATTGCTGGTTTCACCATTTCAGATCTGTGTTGTCTAAGAGTATTAACGTTTTAATT SEQ ID AAGCAAAGAAATGATTTTTAATCTGTATGTAATTGTTTTAAAGCACCCATTTTAAGAGAA NO: AATACTGTGCAATGAAGAAACCAGTTTAGGCATTTGCTATAAACTGAAATATTCCAAAAG 1729 AATCATCTATAACAGCCCTGTAAATTCCTTTAAAATGATAACTAACAGGACAGTTTGACC AATTTTTTTTAAATATACTTCCTTTTATGTGTTCAATAATTAAATGCCTTTGGGTCCT FLNB ADXCRPD.6237.C1_at AAATTAGGTCATGGGTCTGGGATCAGATTCTGTGAAGTTACTGAGCTTCAGGACCTGCAT SEQ ID GTGTTTGTGTGCATGTATGTGTCCCCTGTGTATGTGTGAATGAGAGAGGGAAGAAAAAGA NO: AGAAAGAGAAGCTTTACTTGGATATCTGCCTCTATTATGAAGGACTCTCAAGTAACAGCC 1730 TTTTGATGTAAAGAGCAGCTTCCACTGTCTCTGAAACTGCAGCGAGTTGACAGGTGATGC GGCTGCATTTAGGAAGCCTGGACCCTCTAC LPP ADXCRPD.14604.C1_at AATACCGAACTAATGGTCCTTGTCTCAATGACCTGCCTATCCTTTGTCCCTTCATGGGAA SEQ ID TCTTCTCACAGATCAAGTTACTATGATCTACAAGGCCAGTTCCCATAGCCTCGTTCCACT NO: TACACACGATCTTAACCATTTCTGTCCAGTGGGAGTCACCCACTCACCTCCTAAAACCTC 1731 TATGCATGCCCCATACCCCTAGTCATAATACTCTTATACAAATGTTTAACACTTTGCAGT TGAAGACCCAAT JAK1 ADXCRPD.6270.C1_at GGGATGTAACCTGGCTGAGGTGGGAACCTGCACCCGACTTTTGACAACCATCCCTCATGG SEQ ID CCGGTCCACCTGCCTTTGAAGAAGACCTTGAACAAGGTGGCAGGGGTGGCCCCACAAGGC NO: AAGTTTCAGGAACTTTTTCAAAATCCAAGGGGCAAAAAGGGGCCCCTTAACGTTCCTGGC 1735 CACGGTTTCGGGAACGGCAAACCTTCTCCCACACTTGGGGGAGAGACCTCCCTTGAACGC CCCCGCTCTAAAGAAGACA AHNAK ADXCRPD.15294.C1_at CGTTAAAGGGAACACGAGTATCTCTGCGACCGGTC SEQ ID NO: 1736 AHNAK ADXCRPD.15294.C1_s_at AGGTGGTGTCACTGGCTCACCAGAAGCATCAATTTCTGGGTCCAAAGGTGACCTGAAAAG SEQ ID TTCAAAGGCCAGCCTGGGCTCTCTGGAAGGAGAGGCATGAGGCCGAAGCCTCTTCACCGA NO: AAGGCAAATTCTCCTGATTTAAAAGTAAGAAGCCACGGCACCGCTCAAATTCATTCAGTG 1737 ATGAAAGAGAGTTCTCT PPP4R1 ADXCRPD.5630.C1_s_at ACGTATAATGTATGTCTGGTGTTTTTAACTTGATCATGATCAGCTCTGAGGTGCAACTTC SEQ ID TTCACATACTGTACATACCTGTGACCACTCTTGGGAGTGCTGCAGTCTTTAATCATGCTG NO: TTTAAACTGTTGTGGCACAAGTTCTCTTG 1738 GRB10 ADXCRPD.15300.C1_at CAGAGGTGTGAAGGCTCGCCATAGAGGAGGGCTTGTTGAGTGTCACTCCTGGAGCCTACG SEQ ID GAGTCGCAGGGAGGCCTGGCATGGTCAGGTAGACTTGGTAAGGCCTGACTGCTGGGGAAT NO: GTATCCTGCCAATAGATTCCTGGGCCTGGAACAGCTCTTCTTTGGACACATGCCATCCAT 1740 CTTTGGAATAAGACAATCTGGCATTTATGTACCTGGTGGGTTACC HK1 ADXCRPD.6337.C1_s_at ATCGTGCACGGCAGTGGAAGCCAGCTTTTTGATCATGTTGCTGAGTGCCTGGGAGATTTC SEQ ID ATGGAGAAAAGGAAGATCAAGGACAAGAAGTTACCTGTGGGATTCACGTTTTCTTTTCCT NO: TGCCAACAATCCAAAATAGATGAGGCCATCCTGATCACCTGGACAAAGCGATTTAAAGCG 1742 AGCGGAGTGGAAGGAGCAGATGTGGTCAAACTGCTTAACAAAGCCATCAAAAGCGAGGGG ACTATGATGCCAACAT FAM50A ADXCRPD.6370.C1_at TGGGACAAGTACACGATCCGCTGAGCATCCAGGAGGCTGCGCGGCCCCGGCTCCTCAGCT SEQ ID CCCTCAGTGTGCCCCGTGGTGTCACCGGGACTCCAGGCACCCGCTCCCCTGCGACCATGC NO: CAGGCACGCTGGGAGGAGGACGGCAGCTGCTCGTGTCCTGCCCCTGCCACATCAGTGACT 1743 GCTTTATTCTTTTCCAATAAAGAAGTGCACGTGTCAGAGCTGGAGCGCCTGCATTGTGAG AAACCAA FAM50A ADXCRPD.6370.C1_x_at GACAAGTACACGATCCGCTGAGCATCCAGGAGGCTGCGCGGCCCCGGCTCCTCAGCTCCC SEQ ID TCAGTGTGCCCCGTGGTGTCACCGGGACTCCAGGCACCCGCTCCCCTGCGACCATGCCAG NO: GCACGCTGGGAGGAGGACGGCAGCTGCTCGTGTCCTGCCCCTGCCACATCAGTGACTGCT 1744 TTATTCTTTTCCAATAAAGAAGTGCACGTGTCAGAGCTGGAGCGCCTGCATTGTGAGAAA CCAA CD59 ADXCRPD.15392.C1_at GGGCTATTGAGAGTCAGCACCAGCACTGATCATATATAGGATCAGCCTACTGGGGTTGGC SEQ ID CACGTTGTATGTAGCTGCGAATAGCAAGGAGGGGAACAGCAACATCCCTAGGGAAACCGA NO: TCACAGAAAGGCAGCTCACTACCCCACAGTAAAAAGAACCTTGAGTTTCCCAGTTCAGTC 1745 CCCTGCTGGGTGCATGCTACCCCCCTCCTCTCCCAGAGGCTCTGGACCTACACAGCTGCT GAAAAAGAGAAAATGTCCTTACCTACAATGAACCATCACAGGCACCCA RCN1 ADXCRPD.14742.C1_at GTTGCAATTGTCTCTCACTGACGTATTTGAAGGATATTTGAGCTGGAAAGCTCAACCAAA SEQ ID TGATGCGTTTTTGCTAATATGATGACTTCTCCATAGACTTCTTTAGATTTATATATGTTC NO: CTGTGCACTTATCAACCTTCTCATAGTGCCTCCTGGCTTATCATGGCTTTTGAAAGAATA 1746 GAGGATCTTTGTCACTTTGAC ZDHHC7 ADXCRPD.5764.C1_s_at AAGAGCTGCGTCACAGCCAGAGGGACAAAGTGTGGGTGATCCTGGAGACGCCAGTTTCCG SEQ ID AGATTGTTCTGCATATTCATTTGCACATTGTTGTCTGGGTTGGACATGCGTGTGGGCTTC NO: AGTGTGAGGCTTTTAATATGTATATCCTGTTATCAATAAAACAATTATCCAAGTGGTTGA 1747 ATCCTGTGAGACTTGGCAAGTGTGTGCAAATCAAGTATACTTGACTTTTCAACCTCTT CDC42BPA ADXCRPD.16014.C1_s_at AAGAGCCTCTCCCTGGAGAGCACTGACCGCGGGAGCTGGGACCCGTGAGCTGCCTCAGCA SEQ ID CTGGGACCTCTCGCTCTCCGCTCCCTGCCACTCGCCTCCTCTCACTTTCATCTCTTCCCT NO: CCACCTCGCCTGCTCGGCCTGAAAGCCACCAGGGGCTGGCAGCAGTAGCAGGACAGGGAT 1749 TCAGGAGTTCTGACGACACGACTCTCAGATCCACGCCCCCAGCCTAACAGCAACAACAAA GACAGACTTTCC COL4A1 ADXCRPD.7020.C1_at GGACCTAAAGGTGATCCAGGTATAAGTGGAACCCCAGGTGCTCCAGGACTTCCGGGACCA SEQ ID AAAGGATCTGTTGGTGGAATGGGCTTGCCAGGAACACCTGGAGAGAAAGGTGTGCCTGGC NO: ATCCCTGGCCCACAAGGTTCACCTGGCTTACCTGGAGACAAAGGTGCAAAAGGAGAGAAA 1750 GGGCAGGCAGGCCCACCTGGCATAGGCATCCCAGGGCTGCGAGGTGAAAAGGGAGATCAA GGGATAGCGGGTTTCCCAGGAAGCCCTG KCTD12 ADXCRPD.7032.C1_s_at AGATGCAGTCAAAGTCTTTTCAGACATGCCCAAACTTTGAGAATTTCTTCAACCATCTAA SEQ ID TGCTATAAAGATTTTTGTTCTTCCTGTTCACAACCAGTTGTATAACAGAAATACTAGCTA NO: CTGTTTTCCTTCCTGTGTGTGAAGTAATGAATCATTGATTATGTGACTTGTTATGTATTC 1751 AATTA CCND1 ADXCRPD.16054.C1_at ACCAAGTAGCTGTGGGTTGAACCTGGACGTGAGCTGGTTGCAGGGCCGTTGGGTAGAAAA SEQ ID CCAGCATCTCATAAACAGGTCACTACAAAAATAGGAAGAGTATAAAAATAGAATATATTA NO: TGTCACTATTTCGTCTTCTCTTTATAGTAGCGTATCGTAGGAGTGGGACAAGGTGGCCTT 1752 TCCCGACACTGCTACGCTGGTCTGTGCCCGACAAACCTCACCTGATGTTGTACCTGAGTA CGTTACTAAATCCTCAAGACCTTACACACAGC ITGA5 ADXCRPD.16092.C1_at AGGCCACAGGGTTCCCCTCTAAGCTGCAGCTCCGCTCCTCTGGGTTGAACATGGCGGGGA SEQ ID AGATGGTGAGGGAGGCACTAGCGGACACGATGGGGCGGCCCCTGTATACCACAGCCTTGT NO: CCACACCAAAGGACCCCACAATCAGATCAGGATATCCATTGCCATCCAGGTCTCGGCCTC 1754 CTCGAAGGGCAGAGCCAAAGAAGTCTGGGGTGTGGCTGGCTGCCCACAGGGGCTGCAGAA CCTGGGAAGGCTTAGAGCCCA ITGA5 ADXCRPD.16092.C1_x_at GTTGATGCAGGCCACAGGGTTCCCCTCTAAGCTGCAGCTCCGCTCCTCTGGGTTGAACAT SEQ ID GGCGGGGAAGATGGTGAGGGAGGCACTAGCGGACACGATGGGGCGGCCCCTGTATACCAC NO: AGCCTTGTCCACACCAAAGGACCCCACAATCAGATCAGGATATCCATTGCCATCCAGGTC 1755 TCGGCCTCCTCGAAGGGCAGAGCCAAAGAAGTCTGGGGTGTGGCTGGCTGCCCACAGGGG CTGCAGAACCTGGGAAGGCTTAGAGCCCA PRSS23 ADXCRAD_BM979373_s_at AAAAGGACTCATGGCATTATTAATATAATTAGTGCTTTACATGTGTTAGTTATACATATT SEQ ID AGAAGCATATTTGCCTAGTAAGGCTAGTAGAACCACATTTCCCAAAGTGTGCTCCTTAAA NO: CACTCATGCCTTATGATTTTCTACCAAAAGTAAAAAGGGTTGTATTAAGTCAGAGGAAGA 1761 TGCCTCTCCATTTTCCCTCTCTTTATCAGAGGTTCACATGCCTGTCTGCACATTAAAAGC TCTGGGAAGACCTGTTGTAAAGGGACAAGTTGA FKBP9 ADXCRPD.16135.C1_at GGGCCATCATCAGAATTTGCACAGGCTGCTGGGAAGAGCCATGGCTGTCTGCTGGGAACT SEQ ID CTGCTGGGGCAAGCAAGCCCTTTGACTCTCCTGCCCATCTCAAGAATATTT NO: 1762 FKBP9 ADXCRPD.16135.C1_x_at GGGCCATCATCAGAATTTGCACAGGCTGCTGGGAAGAGCCATGGCTGTCTGCTGGGAACT SEQ ID CTGCTGGGGCAAGCAAGCCCTTTGACTCTCCTGCCCATCTCAAGAATATTTCTAA NO: 1763 CASK ADXCRPD.14972.C1_at CTAAAACCACTAGCCAGAGCAGGAGTACATAAACAGCAAAAATAAATCCCGCAGAAAAGG SEQ ID AGATTCTGATTTATAGAGTTGACACATAATATTATTTAAGACACTCAGTTTTCAACAAAA NO: AATTATGAGGCATGCAAAGAAACAAGAAAATATAGCTCACACTTAGAGGGGAAAAGCAAT 1767 CCCATAGAAACTGTTCCTGAGCAAACCCAGATGTTGGACTTACAAGAAAAAGAGTTACCA AATGGAAAGTATCAAT YES1 ADXCRPD.16243.C1_at GTATCAGTGAGGTAACAGCAACCAGACAAAGTGGGTGATAAAATTTGATGGCATTAGATC SEQ ID TACAGCTGGAGGGAACTGTAGGGAAGAGGAATATGTTAGATAACATGCAAAACCCATAAG NO: ATTAGCAAAACAGTTTTTCCTAAAGATTAAATTTTATATGCTTTCACTCTCAACATTAGG 1770 ATACTTCAGTACAAGAGTTTAGATAGTAACCCAACTAAAGTAATACTGATCGCTGAATTT CAAGTGAGCTCAAAGGTCTCCTTCCC VEGFA ADXCRAD_BX116668_s_at CACTGGCAGATGTCCCGGCGAAGAGAAGAGACACATTGTTGGAAGAAGCAGCCCATGACA SEQ ID GCTCCCCTTCCTGGGACTCGCCCTCATCCTCTTCCTGCTCCCCTTCCTGGGGTGCAGCCT NO: AAAAGGACCTATGTCCTCACACCATTGAAACCACTAGTTCTGTCCCCCCAGGAGACCTGG 1771 TTGTGTGTGTGTGAGTGGTTGACCTTCCTCCA CD55 ADXCRPD.7256.C1_at TTCCTTTGTTGCACAAATAGAGTTTGGAAAAAGCCTGTGAAAGGTGTCTTCTTTGACTTA SEQ ID ATGTCTTTAAAAGTATCCAGAGATACTACAATATTAACATAAGAAAAGATTATATATTAT NO: TTCTGAATCGAGATGTCCATAGTCAAATTTGTAAATCTTATTCTTTTGTAATATTTATTT 1772 ATATTTATTTATGACAGTGAACATTCTGATTTTACAT FLNA ADXCRPD.15612.C1_at GCTACACCATTATGGTCCTCTTTGCTGACCAGGCCACGCCCACCAGCCCCATCCGAGTCA SEQ ID AGGTGGAGCCCTCTCATGACGCCAGTAAGGTGAAGGCCGAGGGCCACTGGCACTCAGTCG NO: CACTGGTGTCGAGCTTGGCAAGCCCACCCACTTCACAGTAAATGCCAAAGCTGCTGGCAA 1773 AGGCAAGCTGGACGTCCAGTTCTCAGGACTCACCAAGGGGGATGCAGTGCGAGATGTGGA CATCATCGACCACCATGACAACACCTACACAGTCAAGTACACGCCTGTCCAGT CRIM1 ADXCRPD.15616.C1_at ACAGATGTCACAGCCGTGCTTATTCTTCAGCAATCCAAGTGGACAATACTTGTCACAGAT SEQ ID TATGGGTCTGCACTTCTTGGGCCTTGGGCGGCACTCACAGATCTCACAGTTTTGGGCATC NO: AGTAAGGAAACCGAAGGGACAGTTCAAGGTGCAGCCTTGTTTACGTTCTGAACATAGTTC 1774 CTCGGTGTTTATGCACTCACAGGTCCGACAACCATTGTGATCGCGTTTGAAACCATTAAT GCAGTCCTTCCCTGTCAGAGTGCAGTTTGATACGGTCCCGAC SPTBN1 ADXCRPD.15631.C1_at GAAATCCAGGGTGCACCTAGCCTCGCGATTGACGACATCTTTGAGAAGGAGCCAAAACAT SEQ ID CGTCACTGACAGCAGCAGCCTCAGCGCTGAGGCCATCAGACAGAGGCTTGCCGACCTGAA NO: GCAGCTGTGGGGTCTCCTCATTGAGGAGACAGAGAAACGCCACAGGCGGCTGGAGGAGGC 1775 GCACAGGGCCCAGCAGTACTACTTTGACGCTGCTGAGGACGAAGCCTGGAT FLNB ADXCRPD.15647.C1_at AGGCTTCTGCGGGTCCCAGGATTCGCAGTCTGGGCACAGACCTGGAGCACAGCTGTCTAC SEQ ID CAGGGCTCCCAGGGCTTTGCCGTCTTGCCAGTTCTGGTTAAAGTTGGTGATGGGCAAGTA NO: GGGGATCTTGTTCTGAATCCACCCCAGCAGCCTCTGCTTTGGCGTCTGCTTCTTGGCATC 1776 ATCATCCCCTTCATCCTCNCACACGGCATGGAGATGGAGTAGTGGAGATCAGCGCCACAC AGACCTAGATGAGCTCAGTTCCATCACAATGGCTTGCTATCGATGACACGA PDLIM7 ADXCRPD.15669.C1_at ATGGCTTACCTCACTTCAGGGAGGCTGTGAGAAGCACTCAGAATCTGGATGTGCCTTGGG SEQ ID GGTGGGCCCCACTGGACTTTCCTGGTGGACCTGGTGTGGGGTGTGAGAGGAGGGTGTGTT NO: TGGCTGCAGCAGACAGGAGAATGGAGTTGCCACTCCGCGTGATGGGGATGGCTGTGGGAG 1777 GAGAGGTCCTGGTGGTGAGGGAATCCGGATCTGAGTGCTGTACCCTGGCAAGTCTGAACG CGCAGTGATCGCTCCACTCACGAGAT FNDC3B ADXCRPD.7332.C1_s_at GAGAAGTGCCCTAATTGAATGTGTTTGAATGTTATCCTTGCACAATTCTTTAAATTGAAA SEQ ID GATAAAATGTTTTACCTCACTGTTGGACATACATTCCAAGCTTTTCAACTCTAGGAGAAA NO: AAGAAAATCATGTTTTCCTGTATTGTAAATTTTAGACTATTTCATATACATTGTATTAAA 1780 ACTGCCATATCAATTTTAATGTATAGATTTTGCAAATATTATGCTATATGTAATACCTAA CTGTATCTGTAGTG COL6A1 ADXCRPD.8056.C1_at CTCGGGACCTGTGGTACCCAGGAATGAAAGGAGAA SEQ ID NO: 1789 COL6A1 ADXCRPD.8056.C1_s_at ACGTACCGGCGCAACTTCACGGCGGCTGACTGGGGCCAGAGCCGCGACGCAGAGGAGGCC SEQ ID ATCAGCCAGACCATCGACACCATCGTGGACATGATCAAAAATAACGTGGAGCAAGTGTGC NO: TGCTCCTTCGAATGCCAGCCTGCAAGAGGACCTCCGG 1790 ZDHHC7 ADXCRPD.8057.C1_at CGGGCCTCGGATCCGATCACATAGGACAGTATGCACCTTAAGATCCTGAAGAAACGGCAC SEQ ID AAAATGTTCAAGTGATGTTTAGAAATAACTTGTGAGGGTGCGTCAGGGAAATCATGCAGC NO: CATCAGGAGACAGGCTCCGGGACGTCGAGCATCATCCTCTCCTGGCTGAAAATGACAACT 1791 A IGFBP3 ADXCRPD.17075.C1_at TGCTCTGCATGCTGTAGCAGTGCACGTCCTCCTTCCCCTTGGTGGTGTAGCCTGGGAGAG SEQ ID GCTGCCCATACTTATCCACACACCAGCAGAAGCCCCGCTTCCTGCCTTTGGAAGGGCGAC NO: ACTGCTTTTTCTTATAAAATCCCTTCTTGTCACAGTTGGGAATGTGTACACCCCTGGGAC 1792 TCAGCACATTGAGGAACTTCAGGTGATTCAGTGTGTCTTCCATTTCTCTACGGCAGGGAC CATATTCTGTCTCCCGCTTGGACTCGGAGGAGAAGT PTPRK ADXCRPD.6814.C1_s_at TATAGCATATGATCACTCCAGAGTGATTTTGCAACCCGTAGAGGATGATCCTTCCTCAGA SEQ ID TTATATTAATGCCAACTATATTGATGGCTACCAGAGACCAAGTCATTACATTGCAACCCA NO: AGGTCCCGTTCATGAAACAGTGTATGATTTCTGGAGGATGATTTGGCAAGAACAATCTGC 1797 TTGCATTGTGATGGTTACAAATTTAGTTGAGGTTGGCCGGGTTAAATGCTATAAATATTG GCCTGATGATACTGAAGTTTA NFIB ADXCRPD.15832.C1_s_at TTCTATTAATATCCTCTTGCATGCTTTAGAAGCCAAAGGAAACAGCCCCCACANNNNNNN SEQ ID NNNCCTAAAGCAATGGTTTCAGTTAAGCCAGGCCCATGGCATCTTTGGAGACAGAAAGCT NO: ACCCTTTCCATTCACGGCAACATGACATTCACAATGTGCTTTCCTAAATGGATGGAAAAC 1799 CCCTCAAAAAAGCCCCTCAAATCTGTGTTTCATAAACTGTACTCTTAGCAATAAAGTTTA TTACAGACCTAAAGTATCTGCATAAACCCGGTTAAT EGFR ADXCRPD.15857.C1_s_at TTTGAAACTCAGTATGCTGCCCCTGTCTTGCTGTCATGAAATCAGCAAGAGAGGATGACA SEQ ID CATCAAATAATAAACTCGGATTCCAGCCCACATTGGATTCATCAGCATTTGGACCAATAG NO: CCCACAGCTGAGAATGTGGAATACCTAAGGATAGCACCGCTTTTGTTCTCGCAAAAACGT 1801 ATCTCCTAATTTGAGGCTCAGATGAAATGCATCAGGTCCTTTGGG WNT5A ADXCRPD.6842.C1_s_at GTTTGAACCTAGAATATTGAATTAAAATGCTGTCTCAGTATTTTAAAAGCAAAAAAGGAA SEQ ID TGGAGGAAAATTGCATCTTAGACCATTTTTATATGCAGTGTACAATTTGCTGGGCTAGAA NO: ATGAGATAAAGAT 1802 CDC14B ADXCRPD.8104.C1_s_at AAATTGTTCATTTTACTGGCTCTGATCAGAGAAAACAAGCAAATGCTGCCTTCCTTGTTG SEQ ID GATGCTACATGGTTATATATTTGGGGAGAACCCCAGAAGAAGCATATAGAATATTAATCT NO: TTGGAGAGACATCCTATATTCCTTTCAGAGATGCTGCCTATGGAAGTTGCAATTTCTACA 1804 TTACACTTCTTGACTGTTNTCATGCAGTAAAGAAGGCAATGCAGTATGGCTTCCTTAATT TCAACTCATTTAACCTTGATGAATATGAACACTATGA PDLIM7 ADXCRPD.8148.C1_at GCAAACCGCAGAAGGCCTCCGCCCCCGCCGCGGACCCTCCGCGGTACACCTTTGCACCCA SEQ ID GCGTCTCCCTCAACAAGACGGCCCGGCCCTTTGGGGCGCCCCCGCCCGCTGACAGCGCCC NO: CGCAGCAGAATGGACAGCCGCTC 1808 PDLIM7 ADXCRPD.8148.C1_s_at GAGAATGCGGGTAGCCTCACACACATCGAAGCTCAGAACAAGATCCGGGCCTGCGG SEQ ID NO: 1809 CYP1B1 ADXCRPD.8150.C1_at GCAAGACGTCAACAGGAACCCGCAGGCCCGGCCTGGACACCTGCTGCCCTCACTGGAAGC SEQ ID TTTAACTCCCACTCGAGTCTCTTGGCGTCGTCAGTGCCAGGAGCGCTTGGATTGGGATGG NO: GGACGGAGAAGGGTGCCATCGCTCGCCGAGCCCCGCTGCACCTTGGGGACCTGGCAAAGT 1810 CGAGGTTTCCTCACAGCGTTGAGATTGAGACTGGGGGTCGGTGAGTGGCGTCAATTCCCA TGCCCTTGCGGCCATCTCACAACTGGAGTCGCAGAAGCGCTCGCT COL6A1 ADXCRPD.6917.C1_s_at TGGCTGCACTCAAGACCCTCGAGATTAACGGTGCTAACCCCGTCTGCTCCTCCCTCCCGC SEQ ID AGAGACTGGGGCCTGGACTGGACATGAGAGCCCCTTGGTGCCACAGAGGGCTGTGTCTTA NO: CTAGAAACAACGCAAACCTCTCCTTCCTCAGAATAGTGATGTGTTCGACGTTTTATCAAA 1815 GGCCCCCTTTCTATGTTCATGTTAGTTTTGCTCCTTCTGTGTTTTTTTCTGAACCATATC CATGTTGCTGACTTTTCCA GALNT2 ADXCRPD.7576.C1_s_at GAGGAGAACTCTTGAAATCTCCATTTTCAATCCCTTCGAAATCACGTATGGTTTCCACAA SEQ ID AGCCGAGTCGTGTCACGTGGCAGGTTTACGTCAATAGTCCCTCTCTCTGCTCCTCCATTC NO: GCAAGTGTCTTCCTGGGCCAGACTCCCCTCCACCTCATGTACTTGCTATATTGAGGATGA 1816 AGTTTTCTATGGTGGGACACTAAATATAAAGCTATATAGAGAAAGAATGTACGGTCAGTT CCCTATGGTTT CCND1 ADXCRPD.15960.C1_at TGCCCGACAAACCTCCACTGGATGGTTTGTCACTGGATGGTTTGTTGGGGTGGTGGTCAC SEQ ID AGGCGCAAAGGACATGCACACGGCCACGCTACGCTACTGTAACCAAG NO: 1817 VCAN ADXCRPD.6973.C1_at TTGAAACTGTGCCACTGACCTTTACTTCCTCCTTCTCTACTGGAGCTTTCGTACCTTCCA SEQ ID CTTCTGCTGTTGGTAAAATGGTGGATCTTCTATCAATTTCAATGACAGTACCCACTTCTC NO: CCAATCCTTCGTCGATAATGGAGGAAGCTGTACCAGAAAACTTTTGCACAGCACTGGGAA 1818 GCACTGGAACAACAGAGCTGCTGACTGTGACCAGTTGCTCACCTGAGCCCTCAGCTGAGG ATGTAAACTCTTCCCAGGGGAAGGCTGAAGTGCTGACCATGGTGCTA CREB3L1 ADXCRPD.15997.C1_at TCCCAAAGTTAGGTGGCCCGTCGCAGGCAGCCCCTAGTAGTCTGGCCTCCTCGCCCGCAC SEQ ID AACCCTTCACCCACAGGCCAGGTGCAATCCCGATGCAGGCTCCTGGCCCGACCCTCTACG NO: CGCTCAGGCGGACAGCTAAGGTCTGGCTGAGTCTCCGGCAGGGGCGTTTGGAATGTGACC 1819 GGTCACCCACTCTCGGCCCTGCATTTGCTTGTGCATGCAAGTCCACAGGTGTAGAGGCAC CCGAACCGTGTGCAT CASK ADXCRPD.17222.C1_at CACAGATCTGCTCCATCCATAAATTCGAAAACCATGTAAAGCATTCCATCTGAGCTATAT SEQ ID GTCTCCAATAACTCTACAATGTGTGGATGTTTCAGCATATGACAGATACTGGCTTCCCGC NO: TTTAGATCTTCTGTACTTAACCCTGGACTTGATGTGAACTTGGCTACATCAACAATTTTT 1822 ACAGCAAATTGTTGCCCAGTTTCTCTGTTGATACATCGTCGTACAACACTGAAGGGACCC TTTCCGATCA MICALL1 ADXCRAD_BP398250_s_at ATGGTCATCACTGGTCTGTCTGCTCTGTTGTCTGTTCTTTCCCTGACTCCCTCCCACCGA SEQ ID AGGCCTGATGGCTACTCACCCCTCTGGGATGGCTATGGGAGAGGAGGAGTGATGGGGACC NO: GCCACCTTTTCTGCAGGAAATGTGCCCAGCAGCTCTTGGTCAAAGCACTGTTGCTATAAG 1823 CTATCTCTGGGATGCCTCTAGGCCCCCTTCCCTCTACACACCTCTGGGAAAAGATTACAC TGTATTAACTCTCGAGGAGTTTCCTCACCAA SYNJ2 ADXCRPD.8240.C1_at GCCAATGTGGGACAGAAGAGCAACCCAGGAAATACAAAGCAAGCGCTGTCAAGAGTGAAG SEQ ID CCGAAGCCCCCCTCACACTCTCTAGAGGGGAAGCAGCATCGTGCTGTGATGACCAGGAAG NO: GGATTACCGAGGGTCCGTTACTAGAACACTGAGATCAAACGGAAGATCCAGATGTGTCTA 1824 CAGATGCCAGTCTTTGGGCTGCTACTGTCCTTACAAACTCATGTC LPP ADXCRPD.16626.C1_s_at CTAGATGATTCCAGTGCCCTTCCATCTATCTCTGGAAACTTTCCTCCTCCACCACCTCTT SEQ ID GATGAAGAGGCTTTCAAAGTACAGGGGAATCCCGGAGGCAAGACACTTGAGGAGAGGCGC NO: TCCAGCCTGGACGCTGAGATTGACTCCTTGA 1828 MARCKS ADXCRPD.8271.C1_at CCGTCCTCGGCCTTGGGCGAAGAAGTCGAGGAGGCGGCCGACGCGGCCTCTCCCTCCGCG SEQ ID GCCGTGGGCGAGCCGGGCTCGGCAGCCTCGCCTTCCGCGGGGGCCTCCTTCTCTACCGGG NO: CTGGCCCCGGCCTCGGGGGCAGCGGCGGCTGCCGGCTCACCTTTCGCGGCCGCG 1829 MARCKS ADXCRPD.8271.C1_x_at CCGCTCAGCTTGAAAGACTTCTTGAAGGAAAAGCGCTTCNNNNNNNNNNNCGGGGTCTCG SEQ ID TTGCTGGGCGAGGGCGTGGCCCCGTCCTCGGCCTTGGGCGAAGAAGTCGAGGAGGCGGCC NO: GACGCGGCCTCTCCCTCCGCGGCCGTGGGCGAGCCGGGCTCGGCAGCCTCGCCTTCCGCG 1830 GGGGCCTCCTTCTCTACCGGGCTGGCCCCGGCCTCGGGGGCAGCGGCGGCTGCCGGCTCA CCTTTCGCGGCCGCGAAAGGCGACGCCGCCCCGCTCCCGGCGGACGAGGGCTCCTCCTTG LPP ADXCRPD.16635.C1_at TTAGTTAAGAACATGACCCGAAGAGTGAAAGGTATTTCCTGTTCCAAATAGGAGCCCAGT SEQ ID CTGCATTTTCTACTACATGATTTAGTAGAAAGACACATTGCATTTGAACCATATTTCTTC NO: TGCTAGCCAATTCCATCTTATCTACAACTTTTTGATAATTATTTTGAGAAATAGATCTAG 1831 ATCACAGCCTTCCAATTCCTAGGCCAGGATACTT LIF ADXCRPD.16683.C1_s_at TCACTGAATCACAGAGCCTTTGCGTGAAACAGCTCTGCCAGGCCGGGAGCTGGGTTTCTC SEQ ID TTCCCTTTTTATCTGCTGGTGTGGACCACACCAGGGCCTGGCCGAAGGAAGAGAGAGTTT NO: ACCAAGAGAGATGTCTCCGGGCCCTTATTTATTATTTAAACATTTTTTTAAAAAGCACTG 1833 CTAGTTTACTTGTCTCTCCTC PRSS23 ADXCRPD.10010.C1_at AGGCTACATATGGATCTTGGTCTCATAAAAAATAAGCACTAAAATTAAGTTGAGTTGAGG SEQ ID TTGAGTTTAGAGTTAGTGCTGCTCATGCCACCCTAAGCTTCCAAGTATCATTCAGTCACA NO: TCTTGTTTCCTGCTTTGGGGTTATTTAACAGGTCATTCGTGAGTTATTACATAACTGGAA 1834 CAAAAGCAAGATAGAATCAAAAGAATACTTAGAGCTGGAGTGACATCAGAAACTGTATGC AACCTCCTTATTGTCAGGACGGGAAAAGGCAAGTCTGGGAAGCAATA TMEM158 ADXCRPD.7689.C1_at AACAAATACACAGGATTTGGTCATTTTCTGCCATGAATCTAGGGCACGTGGGTGCCGGGA SEQ ID AGGAGTCGGGCAGGGGGATGCAATAGAGGGGAAAGGGCCCCATTTCCCTCCTCTCCGTCT NO: TCGGAGCTGCGATCCCACCCTCAGTCCAAGGGCTTAAACATCTGCTTTTCGGAACTGGAA 1836 GCGCAGCACAAACCTTG TMEM158 ADXCRPD.7689.C1_x_at AACAAATACACAGGATTTGGTCATTTTCTGCCATGAATCTAGGGCACGTGGGTGCCGGGA SEQ ID AGGAGTCGGGCAGGGGGATGCAATAGAGGGGAAAGGGCCCCATTTCCCTCCTCTCCGTCT NO: TCGGAGCTGCGATCCCACCCTCAGTCCAAGGGCTTAAACATCTGCTTTTCGGAACTGGAA 1837 GCGCAGCACAAACCTTGCTTTTCAAAGGCGCTGGG FHL1 ADXCRPD.10038.C1_at TGCAGAAGAGTCAATCTACCTAAGTTTTCATTTTTAAATTGCAGCCGGACAGAAATTCAC SEQ ID TTTGCTGCAGGGTTGCTTTTTGCTAAATGCTAATATGATCACTGTGTGCCCTTATTTGAG NO: TAATACTGTAAAATGGGAGAAAAGACGGAAGGAGAACTTTAAAGAAGGGAAGGACCACTC 1838 TTCCCCTATTGATGGTATAGGGCAGAAAGTAAGGACACAAAGAACGAGATTCAAATGCCA TTTTACAGGACAGGAGCCCCTGTCAGTTTACAGCTTGAGACACGCGACGGGTACCGAG MAP1LC3B ADXCRPD.1021.C1_at ACCCTGAGTCTTCTCTTCAGGTTCACAGAACCCGCCGCCTTT SEQ ID NO: 1839 MAP1LC3B ADXCRAD_CX870302_s_at ATCCAATCACAGATCATGAAACAGTAGTGTTCCCACCTAGGAGTGTTAGGAAGTTGTGTT SEQ ID TGTGTTTCAAGCAGAAAAACTGAGCTCCAAGTGAGCACATTCAGCTTTGGAAACTATATT NO: ATTTAATGTAGGCTAGCTTGTTTTCAAATTTTAAAAGTTTAAAAATAAAATACTTTGCAT 1840 TCTAAGTTGCCAATAAAATAGACCTTCAAGTTATTTTAATGCTCTTTTCTCACTAATAGG AACTTGTAATTCCAGCAGTAATTTAAAGGCTTTCAG MAP1B ADXCRPD.10066.C1_at GTTTGGGTCAGTCTCCACCTGGGTATGGTATTATGTTTTATAATCCTGCATCACTTCTAT SEQ ID CCTATCCAGTCATATTTAATGTAGAAAATTAGTTTCCAGTGAAAGTAAAATGTAGGGCTT NO: TTATGAAATTTGTGGGCAAAATCCCC 1843 OPTN ADXCRPD.1062.C1_at GAGAATGATGCTTTCGAAGACGGAGGCAGGCAGTCCTTGATGGAGATGCAGAGTCGTCAT SEQ ID GGGGCGAGAACAAGTGACTCTGACCAGCAGGCTTACCTTGTTCAAAGAGGAGCTGAGGAC NO: AGGGACTGGCGGCAACAGCGGAATATTCCGATTCATTCCTGCCCCAAGTGTGGAGAGGTT 1844 CTGCCTGACATAGACACGTTACAGATTCACGTGATGGATTGCATCATTTAAGTGTTGATG TATCACCTCCCCAAAACTGTTGGTA ATP2B4 ADXCRPD.10094.C1_at AGCCATCTTTATACTTAGGGAAGAAAAATTGTTGGGTTCTAGACTTTTTTAATATAAATT SEQ ID TTGTTGATATGGAATTAGGTAAGTTTAAGTGTCTATGTGCATATGTTTTTATATAAGTTT NO: TTTCTATTCAGTTTACTGATCCAACTGGCAGTGGGTAAATATGGCATAAGTTAATAACAC 1845 TTTTCCCCAAAATGGTGCTTTGGATTTGAAAAGGGTCTGATGGGGAGAAGGAGAACGTAT CATCCTAGCTTCCTCTCTTATAAACCTAGAAAAACGGGTAGTAAACTGTGGATAGTCA CNN3 ADXCRPD.1098.C1_s_at AAGAGCAAATGCATCACCCAGGCCTAAATGTCCACAGGCCACTTTTGTACATGCTCTTTT SEQ ID AGAAACACCACTCTGAAAAGATCTTGTTCGCTAGGTAAGAGAATGAGTACACATATAATC NO: ACAAATGCACACTGATCATGACTTTATTTAAAAATTAGCAAACAATACTGTAGAAACATT 1847 GATATGTAAATTTCTAAAATGCTGCATCTTAAATTTAGTTGGCAAAGACCACATTTAGCA ATAAGCATGAGTTTAGTCTTCCATGTAGAAACCAGATA NPC1 ADXCRPD.8331.C1_s_at GCAATAAATTAACTTTGTACACATTTTTATATAAAAAAACAGCAAGTGATTTCAGAATGT SEQ ID TGTAGGCCTCATTAGAGCTTGGTCTCCAAAAATCTGTTTGAAAAAAGCAACATGTTCTTC NO: ACAGTGTTCCCCTAGAAAGGAAGAGATTTAATTGCCAGTTAGATGTGGCATGAAATGAGG 1849 GACAAAGAAAGCATCTCGTAGG FHL1 ADXCRAD_BP325154_s_at GTGATTCCTAGGACTTTTCCTCAAGAGGAAATCTGGATTTCCACCTACCGCTTACCTGAA SEQ ID ATGCAGGATCACCTACTTACTGTATTCTACATTATTATATGACATAGTATAATGAGACAA NO: TATCAAAAGTAAACATGTAATGACAATACATACTAACATTCTTGTAGGAGTGGTTAGAGA 1850 AGCTGATGCCTCATTTCTACATTCTGTCATTAGCTATTATCATCTAACGTTTCAGTGTAT CCTTACAGAAATAAAGCAGCA ELF4 ADXCRPD.7745.C1_s_at TAAGAAATGTCAGCCACGGAAACAACTCTATTATCTGGTGACTTTGGGTAATGTGAATCA SEQ ID GTGCCTGAGGACCTTTGCTGTGTCCTTGGTACAGAACCATCCACTTGACCTAACTACCTC NO: CCCTGGACCGCTCTCGCTCTTCTCTTCTTTGTTAAGCCAACAACTATCACCCTCTCCTAC 1853 TCTTCTTCTCCCTGCCCCCTGGAGGGCACTGTGTTTGGTTGTGCAAATGTATTTACTATG CGTGTTTCCAGCAG LAMB1 ADXCRPD.10103.C1_at GATTTTTCTACTGGTCTCATTGCTGGCCAGTGTCGGTGTAAATTAAATGTGGAAGGAGAA SEQ ID CATTGTGATGTTTGCAAAGAAGGCTTCTATGATTTAAGCAGTGAAGATCCATTTGGTTGT NO: AAATCTTGTGCTTGCAATCCTCTGGGAACAATTCCTGGAGGAAATCCTTGTGATTCCGAG 1854 ACAGGTCACTGCTACTGCAAGCGTCTGGTGACAGGACAGCATTGTGACCATGTGCCTGCC AGAGCACCTGGGGCTTAAGCTATGAGTTGGATGGATTCGCCATGTACTCGACC COL6A2 ADXCRPD.10104.C1_at TTCGTCATCAAACGTGGTCAAACAGGCTGGGTGCCATCGCTAAGGACCCCAAAGTCCGAG SEQ ID ACAGGGACGCGTGTGGGCGTGGTGCAGTACAGCCACGAGGGCACCTTTGAGGGCATCCAG NO: CTGGACGGACGAACGTATCGACTCCC 1855 COL6A2 ADXCRPD.10104.C1_s_at GACCCCGGTCTCACGGAGTGTGACGTCATGACCTACGTGAGGGAGACCTGCGGGTGCTGC SEQ ID GACTGTGAGAAGCGCTGTGGCGCCCTGGACGTGGTCTTCGTCATCGACAGCTCCGAGAGC NO: ATTGGGTACACCAACTTCACACTGGAGAAGAACTTCGTCATCAAACGTGGTCAAACAGGC 1856 TGGGTGCCATCGCTAAGGACCCCAAAGTCCGAGACAGGGACGCGTGTGGGCGTGGTGCAG TACAGCCACGAGGGCACCTTTGAG ADAM9 ADXCRPD.10109.C1_s_at ATTTTCATAGAAATTAGGCTGGAGAAAGAAGGAAGAAATGGTTTTCTTAAATACCTACAA SEQ ID AAAAGTTACTGTGGTATCTATGAGTTATCATCTTAGCTGTGTTAAAAATGAATTTTTACT NO: ATGGCAGATATGGTATGGATCGTAAAATTTTAAGC 1857 ADAM9 ADXCRPD.10110.C1_s_at TTAAGTGTTTAAGTGTTATTCTGAATTTTCTACCTTAGTTATCATTAATGTAGTTCCTCA SEQ ID TTGAACATGTGATAATCTAATACCTGTGAAAACTGACTAATCAGCTGCCAATAATATCTA NO: ATATTTTTCATCATGCACGNNTTAATAATCATCATACTCTAGAATCTTGTCTGTCACTCA 1858 CTACATGAATAAGCAAATATTGTCTTCAAAAGAATGCACAAGAACCACAATTAAGA EGFR ADXCRPD.10120.C1_at GCTGTGGAGCCCTTAAAGATGCCATTTGGCTTGGCTTCCTTGGGAAAGAAGTCCTGCTGG SEQ ID TAGTCAGGGTTGTCCAGGCTAATTTGGTGGCTGCCTTTCTGGGCCCAGTGGCGAGGGCTG NO: TCGAATGTGCTGTTGACACAGGTGGGCTGGACAGTGTTGAGATACTCGGGGTTGCCCACT 1860 GCAGTGCTGTGGGGGTCCTGGTAGTGTGGGTCTCTGCTGGGCGCGGGGTTCAGAGGCTGA TTGTGATAGACAGGATTCTGCACAGAGCCAGCGGCCTT EPAS1 ADXCRPD.10121.C1_at CGAGCCAGCCATGGGCCACGGAGTTGAGGAGCCACAGCACCCAGAGCGAGGCTGGGAGCC SEQ ID TGCCTGCCTTCACCGTGCCCCAGGCAGCTGCCCCGGGCAGCACCACCCCCAGTGCCACCA NO: GCAGCAGCAGCAGCTGCTCCACGCCCAATAGCCCTGAAGACTATTACACATCTTTGGATA 1861 ACGACCTGAAGATTGAAGTGATTGAGAAGCTCTTCGCCATGGACACAGAGGCCAAGGACC AATGCAGTACCCAGACGGATTTCAATGAGCTGGACTTGGAGACACTGGCGAGCTAG GATA6 ADXCRPD.7794.C1_at CCGTACACTCCTCTCTGGTTTTCTTCCTCAAAGGAAATTTATGCATGTAATCCACAAGCC SEQ ID GAAGAACCCATGTTTTTCTTTGGAAAAGGCTACGCCCTTTCAGGGTTTCCTTTTCTCGGC NO: TGTGTTGCCTTCCCATCAGAAGCTGTCTCTTGCCCTCCCCATTATGGGATGTGCGAAATG 1862 AAGGAAAACAGAGACACTGCTGGGCATTTGTCTCCATGAGTTGATCCAATCAGAAATCTT TGACTTTTCACACATGTGTCCAAAAATGAGTG FLNA ADXCRPD.10169.C1_at TCAGGCAACCTGACGGAGACCTACGTTCAGGACCGTGGCGATGGCATGTACAAAGTGGAG SEQ ID TACACGCCTTACGAGGAGGGACTGCACTCCGTGGACGTGACCTATGACGGCAGTCCCGTG NO: CCCAGCAGCCCCTTCCAGGTGCCCGTGACCGAGGGCTGCGACCCCTCCCGGGTGCGTGTC 1867 CACGGGCCAGGCATCCAAAGTGGCACCACCAAC RND3 ADXCRPD.1153.C1_s_at CACTCAGTTCTATGTCTTACAAGCACTTTGTCTTGTCTCTGCAAGAAAATTCGATTCCAG SEQ ID TCATTTCCCATAAAATACAGACATTTTACCAACATAATATGCTTTGATTGATGCAGCATT NO: ATGCTTTGGGCAGTATTACAAAATAGCTGGCGAGTGCTTTCTGTATTT 1868 COL4A2 ADXCRPD.10175.C1_s_at GCTATCAAGGGCCTGATGGACCCCGGGGACCCAAGGGAGAAGCCGGAGACCCAGGGCCCC SEQ ID CTGGACTACCTGCCTACTCCCCTCACCCTTCCCTAGCAAAAGGTGCCAGAGGTGACCCGG NO: GATTCCCAGGGGCCCAAGGGGAGCCAGGAAGCCAGGGTGAGCCAGGAGACCCGGGCCTCC 1869 CAGGTCCCCCTGGCCTCTCCATCGGAGATGGAGATCAGAGGAGAGGCCTGCCGGGTGAGA TGGGACCCAAGGGCTTCATCGGAGACCCCGGCATC LPP ADXCRPD.9098.C1_at GCATCCACAGTGAATGGGATCCCATCCAGGCTGCGGTGGCACATCACCGCAGGGTGAAAC SEQ ID AGGTGAGGATGATTAGGCCTTCCCGGTGGCTCGGAGAATCCGCTCCATGATGGGCTTGGA NO: ACACACATTGCACTGCTCCAGAGTATTAATGTAGCAGGGCTCGCAGTATGCTTTCTTTTC 1872 CACAGCATAAAATGGCTGCCCTCGGAGCTTGTTGTTGAGATGATGCANGTNAAACAATCC ACGTGGAAGACCTGATCCATGGCAGTGCATTCTGTACCTTTCCCAACTA YPEL5 ADXCRPD.17470.C1_at TGGAAAAAGACAACCCAGCAGTTCTGTCCCATCTCAGAAAAAGTTTCCAATCAACACCAA SEQ ID TTATGTGGTGACAAATAACTAGGAATGGTGACATCTTTGGGCCAAGACTGACAAGGAAGA NO: ATGGGCTCTGGTGCTACGGTTCATCTCCAACAAGAATATGGCACACCGGCCAGCACAAGC 1874 CATGCTAACACTGAGCCTTTAGCGCTGGGCACAGATTCAGATCTCTTCTCTGAAGCTAGC AAATCAA ZFP36L1 ADXCRPD.7802.C1_at TCCTTGAAACTTCCCCAAGTGTCTGCACAACTTACCTTTTCCCGACTTCTCTTCGACACT SEQ ID CGGCTCCCTTCGGCAAACCGGGCAGGCCGAGGACATTAGAAATTTGGGACGCACAGAATG NO: TTCAAGCCTAGGATTTTATGTTGCTGTTTTTTTTCCAGCGGNGCGTAGGGTGGGGCGCGG 1875 TGCTGGGGGGACTAGGGAAACTTTTTCCCCAGGAGGACATGGTCTGGCGGGCGCGAGCGC GGCACAATTTAGTGCGTCGCACGCGTCGACACT RRBP1 ADXCRPD.7803.C1_s_at GAGGCGTTTGACGTTCTAGGTTATCCCTCCGCAAGGGGATTCTCTGCCTGGCTTGCTGAT SEQ ID GTCATATCTGGTGGGGAGTGGATTTAGATCTGACACTTTTTCTGCTCTTCAGAAGCAGAA NO: GCACAAGCCCAGTATCCCAATTCTGGTTTAATCTCAAA 1876 MAP1LC3B ADXCRPD.17493.C1_at GAGTCTCATTAGTGTCTGTGTTTACTGAACGCTGCGGACATCTTTTCTATATACAGTAAT SEQ ID TCTTCCACCCTGTCACAACAAAGAGAAGTTGAGTGGCAGGAATGGGAAATCTTTACATGC NO: TTCTTTGGGAAAGAAAAATGCTTATTTGTACATTGTTCTATTGTGTGAGACCTACATAGG 1877 GTTCTGTGTAAGGCCGAGTCAAGCTGTCATCACTTTCCTTGGTAAGTTTGAGAGCTTTAT CTAGCGGACACGTTCTGAAGT CAST ADXCRPD.7890.C1_s_at AGTTAAGGTATCTGGTATCTGCATGTAAAATCTTCAGCTGGTGGATGGTGACTTTTGAAG SEQ ID AACAAAAGGCTTTGGCAACAGAAAACAATTGTTCTGGGTGATTTCTAGAATGGTTTTTGT NO: TGAGTCTCTGAACATCCTAAATATTGGTTTGTTA 1879 CAV1 ADXCRPD.1261.C1_s_at TCAAGTTCCAAGTTGCTAATACAGCAACAATTTATGAATTGAATTATCTTGGTTGAAAAT SEQ ID AAAAAGATCACTTTCTCAGTTTTCATAAGTATTATGTCTCTTCTGAGCTATTTCATCTAN NO: NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTGCA 1881 TGTGGATCAACCATCGCTTTATT CD59 ADXCRPD.18131.C1_s_at GGCAAGCTCTTCACTATGACAGTAAAGGCTCTCTGCCTGCTGCCAAAGCCTGTGACTTTC SEQ ID TAACCTGGCCTCACGCTGGGTAAGCTTAAGGTAGAGGTGCAGGATTAGCAAGCCCACCTG NO: GCTACCAGGCCGACAGCTACATCCTCCAACTGAACCTGATCAACGAAGAGGGATTCATGT 1883 GTCTGTCTCAGTTGGTTCCAAATGAAACCAGGGAGCAGG CORO1C ADXCRPD.18147.C1_at GATATCCAAATAGCTTTATTGGCAAGAATCCACCTCTAGGATGTCCTTCCCGTATTTTGC SEQ ID TTCATCCTTGAAACTAACATCCTAGGAGCAACACATGCTGCCTCTTTTTAAAGGGGCCTG NO: GAGGCGTGGGGCAGACCCTTGAAGGAAGGAAGGAGTTGGTGAGCTGAGATGGTGAATGAG 1886 TTGACATTGTGGGCTATCTTTCAGAATCCGTTTCTGAATCTATGTAGCTACTTGATTACA GTTTGGGCTTCTC VCAN ADXCRPD.18158.C1_at ATTTCAACGACTTCAAGTCCTTCCTGCTTACACAGCCGAACTAAGACCACCTCACTGGTG SEQ ID GAAGACCAAAGAGGCCATTTGCACCTCAGGCTGCTTTCTGACGCCACAGACCTCCAGCAA NO: GCACAAATATTTCAACCTGCACATTAATAGTAGATATTATTCGAGGTCAGCAGA 1887 CDC42BPA ADXCRPD.8518.C1_s_at AAAGCAAGGGCTTCAACAGCCTTAACCAAATATTATTCCCCATAGCCAGTGGAAAATGGA SEQ ID TGTGACAACCCCAGTGCGCAGGCCAGAGTGAGTGAGCCCAGCACGGCGCTCCGACTGGCT NO: TCCTCTCTCAGGTGCTGGATTGTGGGGTTAGTGGCATTTCCAGCTGGATTCCTCCTGTTG 1891 TAGTTGCCATAAGGAAATGAGATGCAGAATCAGAAGGATCTATTTCTACAGAATCATTTC ACCAGTTAAGCACATGAGTAGAGA FLNB ADXCRPD.18190.C1_s_at TGGACTCAAGCTATTGTTCACCTCAGCCTCCCTTTTGTGATTTCTAATTTATTTTTAGTA SEQ ID ATTAACAATGTATTGCTTGTATAAATTTT NO: 1892 LAMB1 ADXCRPD.478.C1_at TTTTAATCACATTTTGTATGGAGTTAAATAAAGTACAGTGCTTTTGTA SEQ ID NO: 1896 LAMB1 ADXCRAD_CN388541_s_at ATGCCAGAAGGAAAGCCGAAATGCTACAAAATGAAGCAAAAACTCTTTTAGCTCAAGCAA SEQ ID ATAGCAAGCTGCAACTGCTCAAAGATTTAGAAAGAAAATATGAAGACAATCAAAGATACT NO: TAGAAGATAAAGCTCAAGAATTAGCAAGACTGGAAGGAGAAGTCCGTTCACTCCTAAAGG 1897 ATATAAGCCAGAAAGTTGCTGTGTATAGCACATGCTTGTAACAGAGGAGAATAAAAAATG GCTGAGGTGACCAAGGTAAAACA KDELR2 ADXCRPD.491.C1_s_at AAGGTCTGGAAGCTCTGTGTAGCCATTCCTTCTGCAGTCATCCTACCCAAGTAAAAGTAA SEQ ID CCTTGGCTATGTTACCACCGTTTTGGTCACCCAGGAGGACATCTTAGCAAGGGTGCCTGC NO: GAGGGAGTGTGGGACTGGGCCTCATCCTCGCCGGCGTTGGAAACCAAGGCCTTGTATGCC 1898 ACGCCTTATGAAGCACTGTTTCACAGTTACTTTCACTTCCCGAA SCRN1 ADXCRPD.2301.C1_at CACGTGCTTCCTTACTAAGGCTGAGAGCTCAACTGAAGACCTTCCCCAATAAATGACAGA SEQ ID TGGCTCTTCAGTCAGGAATGCAGTTAGTGGTTTCATGACAGACACACTGGTCCCACCTGG NO: CTTCCCTGCTGAACCACCCAGTACTGAATAACACCTGTACCAATGTGGGATGACATCAGC 1899 TAGGAAGCAAAGTAATTTGCCTGGTTGATGATTATTTTTTATACCTAATGATTCACCCAA TAGTAAAGGAACCCCACAGCTAAGATC CAPN2 ADXCRPD.6630.C1_s_at TGCGCTTGATCAACTGAACCAGTATGCCAAAACCAGGCATCCAATTTGTAAACCAATTAT SEQ ID GATAAAGGACAAAATAAGCTGTTTGCCACCTCAAAACTTTATGAACTTCACCACCACTAG NO: TGTCTGTCCATGGAGTTAGAGGGGACATCACTTAGAAGTTCTTATAGAAAGGACACAAGT 1900 TTGTTTCCTGGCTTTACCTTGGGAAAATGCTAGCAACATTATAGAAATTTTGCCTTGTTG CCTTATCTTCTTCCAAATGTACTGTTAA FLNA ADXCRPD.3150.C3_at CTCATGGGTCTTGCCCGATGGGCTGGTCACCTGGGCTGTCATATCCTGGATGCTAATTTC SEQ ID AGGGATTTTCAGGCTGAGGTCACAATGACTACCAACGTTGGCCACTGAAGGAGCCCGACG NO: CCTGCGGGTGATGCTCTCTTTCACCCGGCCCTCGCCTGTCACCTTCACAGAGAAGGGGCT 1902 GCCAGGCACGTGCTGGTCGGCAAACTTGATGTTGATGATGTAGTTGCCTGGCTCTGTGGG GCAGTAGGTGACCCTGCACGTCC SEPT7 ADXCRPD.177.C1_s_at ATAAAGGACCGTTTACCTCTTGCTGTGGTAGGTAGTAATACTATCATTGAAGTTAATGGC SEQ ID AAAAGGGTCAGAGGAAGGCAGTATCCTTGGGGTGTTGCTGAAGTTGAAAATGGTGAACAT NO: TGTGATTTTACAATCCTAAGAAATATGTTGATAAGAACACACATGCAGGACTTGAAAGAT 1905 GTTACTAATAATGTCCACTATGAGAACT RAB32 ADXCRPD.4345.C1_at TTTGTCATTGTTGCCATCATATGGAAGATAATGTTTACATCCTTTTAAACATTTTTATAT SEQ ID GACAATTCCTCAGGATTTGGTAAGGCTTCCAAGTTGTAGCTT NO: 1906 RAB32 ADXCRPD.4345.C1_s_at ATGTCATGTTAGCTGGGAGTCTTCCCACATGTGGCACTTCAAAAGGCAGCACCACTGGGC SEQ ID GCCTGCACTTATTTGAAAATGGAACTTTGGGAGAAGTATCCCTGCTAGTGGCTCTGTAAC NO: TTAACAGATGACAATTAGGCTTTT 1907 MARCKS ADXCRPD.2741.C1_at GGGTCTCCTCTCTCGGGCGGCTACTACTCCACACCGAGAGGGAGTGTCTTACAAGGCGGC SEQ ID CGGCGTGCAAACAAAAAAATAATATAACCGNNNNNNNNNNNTCGGTCGCACCTATATTCG NO: AGCAAAGAAAAGCGTGGGTGGTAAAGTATATTCTATAAACACAATTTCCTCGCGCCCACC 1908 ACGGTGGAATACCCACTCCCCATAAAACGGCCGGTGGGAGAAGACTCTCGAACACCGCCC G CD55 ADXCRPD.1207.C1_at TTCTATCTGGGCACACGTGTTTCACGTTGACAGGTTTGCTTGGGACGCTAGTAACCATGG SEQ ID GCTTGCTGACTTAGCCAAAGAAGAGTTAAGAAGAAAATACACACAAGTATACAGACTGTT NO: CCTAGTTTCTTAGACTTATCTGCATATTGGATAAAATAAATGCAATTGTGCTCTTC 1911 LEPRE1 ADXCRAD_CN309928_s_at AGACGGATGGGTGACTAGACCCATGGAGAGGAACTCTTCTGCACTCTGAGCTGGCCAGCC SEQ ID CCTCGGGGCTGCAGAGCAGTGAGCCTACATCTGCCACTCAGCCGAGGGGACCCTGCTCAC NO: AGCCTTCTACATGGTGCTACTGCTCTTGGAGTGGACATGACCAGACACCGCACCCCCTGG 1914 ATCTGGCTGAGGGCTCAGGACACAGGCCCAGCCACCCCCAGGGGCCTCCACAGGCCGCTG CATAACAGCGATACAGTACTTAAGTGTCTGTGTAGACAACCAAAGAATAA LDLR ADXCRPD.1293.C1_s_at CCCTGGTTGCTGTATTTGTTCAGTGACTATTCTCGGGGCCCTGTGTAGGGGGTTATTGCC SEQ ID TCTGAAATGCCTCTTCTTTATGTACAAAGATTATTTGCACGAACTGGACTGTGTGCAACG NO: CTTTTTGGGAGAATGATGTCCCCGTTGTATGTATGAGTGGCTTCTGGGAGATGGGTGTCA 1916 CTTTTTAAACCACTGTATAGAAGGTTTTTGTAGCCTGAATGTCTTACTGTGATCAAT PTRF ADXCRPD.2246.C1_x_at TCTCCCCAGTCACAGCCTGAAGGGAGGCCCCGAGAGCTTCCTCCTTCCCCCCACCTGCTC SEQ ID CTTACCTTCTCTGCCCTGCTTTTTAGAACTGCAGTTCATTGTTTTAAGGGATTGGGGGAG NO: GGAGCCTGGGGACACAAACCTTTTATACAATACAAAGCTTTGCNNNNNNNNNNNNNNNNC 1917 TTCCCTTTTCCCNTTTCTCGGTTCTCTTTTCTCTCCTCTGGAATGGGCTGAAGACCCCTC TGCC FKBP9 ADXCRPD.3075.C1_s_at AGAAGTTTGGGCTGATCGCCAGTGATAGTAAACAAAATCTGTGCAGAGGGCCTTAGCATG SEQ ID GGATGTGTCCAGTATTGAAAAGGCTGCACTGCCAACCATGATTTGTGAGCCTTCTGGGAA NO: ATTTTGTTATTAAAGGAATATATAGTGTCAGACGGAAGTTATAATCATCTTGGAGGAACC 1918 ATAAGAAAAGGTGTCCAGGGTATCTATATAAA S100A11 ADXCRPD.77.C3_at TTCTCACAGGAGTATAAGGTACAGGATAGGGATTATTAATATTCCCATTTGCCAGATGCA SEQ ID GAAACAGACTAAAAGAGGTGAAGTGACCTGCCTAAGGGCCAGACCTGGGCCTTGAACCAA NO: AGGTTTTCCCACTCCTAGTCCAGGGCTCTTTCCATGATATAAGGGGCTATTCAGTTTGGT 1920 AAAGCCAGTGGAACACTTTCTTTCAAGTGTTGCATGCACTTCCCAATAGATAAACT FOXN3 ADXCRPDRC.8652.C1_s_at GAGCCTTCACGTAAATGGGTCCAGTCATGCCTCCCAGTAAGAAGCCAGAAAGCTCAGGAA SEQ ID TTAGTGTCTCCAGTGGACTGAGTCAGTGTTACGGGGGCAGCGGTTTCTCCAAGGCCCTTC NO: AGGAAGACGAGTGACCTCGACGTTTTCTCTGCCTGACATCCGATTATAAGAAGGGGGCCA 1924 TGGAAGATGAAGAGCTGACCAACCTGAACTGGCTGCACGAGAGCAAGAACTTGCTGAAGA GCTTTG LAMB1 ADXCRPDRC.11010.C1_at GCCGATGACTGCGACCCAGTGACTGGGGAGTGCTTGAACTGCCAGGACTACACCATGGGT SEQ ID CATAACTGTGAAAGGTGCTTGGCTGGTTACTATGGCGACCCCATCATTGGGTACAGGAGA NO: TCACTGCCGCCCTTGCCCTTGCCCAGATGGTCCCGACAGTCGGACGCCAGTTTGCCCCGG 1925 AGCTGCAACCAAGATACCTGTTACTTTACTGCTGCCTGTGTTTGTGATCCTGGATACATT GGTTCCAGATGTGACGATCTGTGCCTACAGG FOXN3 ADXCRPDRC.8765.C1_s_at AAAGGGTCGTTGTGGTGCATAGACCCAGAGTATAGACAAAATCTAATTCAGGCTTTGAAA SEQ ID AAGACACCTTATCACCCACACCCACACGTGTTCAATACACCTCCCACCTGTCCTCAGGCA NO: TATCAAAGCACATCAGGTCCACCCATCTGG 1928 ARID5B ADXCRPDRC.11117.C1_at GATTTTTGTGGGACAACTCTAGCCCACAAACTGACTGGCTGGTGAGTCTTGACTCCCTTC SEQ ID CAACACAGATGCCCAGGCACCTCCAGATCATTCACTTCGCACGTGGGCCTTGTGAAGGGA NO: TTTGTGAATATCCAGGAAGAACTTAGAGGACCCCATCTGAGTTCGGATGGTCAGGAAACA 1931 ATCTGGGCAAAAAAGAGGCAGGCATTTCAAAGGAAGGGGCAAGGAAGACTGGCAAACAGA TGGCAAGGC KDELR3 ADXCRPDRC.11126.C1_at GACCTTTTCATCAATAGATCGCCCTTAAAGACCCATTGTAAGGTCATAAAAAACCTCGGC SEQ ID CAACTGCACAAAGATGGTGCCTCACTGCAACAAGAAACCTTAAGGTGTCTTACCGACGAA NO: ATAAAAAACATAAATGATTGTTCTCCAAGGCCTGAGGGCAAGACTCATGATGGGCAAGTC 1932 AACCCCAATCTGGAACAATGTCCCTCCTCTTAG LEPROT ADXCRPDRC.1565.C1_s_at CTGAAGCCCCACTCTGGACCCAGGACATTTTGATGAGATCCAAAGGAGTTGTATGCACAT SEQ ID GAAAGTTTGAGAAGCATCATCATAGAGAAGTAAACATCACACCCAACTTCCTTATCTTTC NO: CAGTGGCTAAACCACTTAACCTCTCTGGGTGTTACCTGCTCATTTGTTT 1933 MALT1 ADXCRPDRC.2292.C1_at GGGTGATGCCCTACGTTTACTGAATTTTCCACTTGGATCCTAGATATTGGATCCCAAAAG SEQ ID ATGGCAAATTAAAGGGCACACCCTGAAAGAAACCTGGGAAGCTAACTTGGGTATTCCAAA NO: GGAATTTTTCCCCAAGGCATTTGCCCTTCTATACCCAAGACTTCAGGTTCCCCTGGCAAA 1935 SYNJ2 ADXCRPDRC.17920.C1_at TAAGAGAATTCCCGCCAAAGGGCCAAAATTGGCCTGGGTAAACTTTTGCAGGAACGGTCA SEQ ID CTCGGCTCTCA NO: 1936 SYNJ2 ADXCRPDRC.17920.C1_s_at GTCACTCGGCTCTCAGTGTCCTGGACGTGGACGGTATGAAGGTGAAAGGCAGAGCAGTGA SEQ ID AGATTAGACCGAAGACCAAGGACTGGCTGAAAGGTTTGCGAGAGGAGATCATTCGGAAAC NO: GAGACAGCATGGCCCCCGTGTCTCCCACTGCCAACTCCTGTTTGCTGGAGGAAAACTTTG 1937 ACTTCACAAGTTTGGACTATGAGTCA POFUT2 ADXCRPDRC.17928.C1_at AATGCTGGAAGTGGCCCCAGCATCCTTCCGCCANNNNNNNNNNNNNNNNNNNNNNNNNNN SEQ ID NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCAGGACAGCTCATTTTATATTATCAAAT NO: CCCGTTCTTTTAACACGCGACAGTCGCGCAGTTTAATCTTCCCTCCCCCCCTATGCCTCG 1938 CCCATTGCCCGTTGGCGGTTATACGCAGTATCCTGATAACGTAGTACCCGCGC EPAS1 ADXCRPDRC.3002.C1_at TGAACGTGCCCGTGCTTGGGAAGCTGCACGCTCCTGCAAGGAGGGGACCTCTTTCAGAGC SEQ ID TCCTGGACCAGGACACTTGAGCCAGGCCTTCTACCTGGCATCA NO: 1941 EPAS1 ADXCRPDRC.3002.C1_x_at GAACAGCAAGAGCAGGTTCCCGCCACTGTGCTACGCCACCCAGTACCAGGACTACAGCCT SEQ ID GTCGTCTGCCCACAAGGTGTCAGGCATGGCAAGCCGGCTGCTCGGGCCCTCATTTGAGTC NO: CTACCTGCTGCCCGAACTGACCAGATATGACTGTGAGGTGAACGTGCCCGTGCTTGGGAA 1942 GCTGCACGCTCCTGCAAGGAGGGGACCTCTTTCAGAGCTCCTGGACCAGGACACTTGAGC CAGGCCTTCTACCTGGCATCA ALCAM ADXCRPDRC.1829.C1_s_at TTCTAGGTATAGAACTATGTTATTGAAAGGAAAAGGAAAACTGGTGTTTGTTTCTTAGAC SEQ ID TCATGAAATAAAAAATTATGAAGGCAATGAAAAATAAATTGAAAATTAAAGTCAGATGAG NO: AATAGGAATAATACTTTGCCACTTCTGCATTATTTAGAAACATACGTTATTGTACATTTG 1947 TAAACCATTTACTGTCTGGGCAATAGTGACTCCGTTTAATAAAAGCTTCCGTAGTGCATT GGTATGGATTAAATGCATAAAATATTCTTAGACTCGATGCTGTATAAAATATTA ARID5B ADXCRPDRC.10890.C1_at TTATACTTTTGTAGACTCTCCTGTGTTGTCCATATTGTATACTTTTGGTGATTCCAGCTA SEQ ID TTTAACCTCTATGTCTCTGCTAAGGTGATTATTTGTATATAGCACTCGGCCCTGTGATAT NO: TATAGAGTTTCCCGTGGAGA 1948 FOXN3 ADXCRPDRC.12156.C1_at GTGAACGATCATTTCTGACTTAACCGTGAGATGCTCACGAGTACCCTTCCTGTTGTTTTG SEQ ID TTAGCATTGAAATCGAGACTATTTATTTGGAATATATACAACAGTGTTTTTCCACTGTAT NO: TTCATTTGCAAAAGTTGAGAACTGCTTTCTCTACCCTTTGCCAAATTAATGAATATCCAA 1953 TATGGGATTTTCAAAGACTCCGATATGGTGAACCTATTAAACCTAGAAATTGTATTCATC CTTTCATGACTGTGGCCTGAGTTCCCCAG AHNAK ADXCRPDRC.3149.C1_s_at TCCTGGCAAGGCATTCGCTCCTGAGCGGAATCCTGCAAAGATGGAGAAGGAGGAGACAAC SEQ ID CCGGGAGCTGCTGCTGCCCAACTGGCAGGGTAGTGGCTCCCACGGGCTGACCATCGCCCA NO: GAGGGACGACTGTGTGTTTGTGCAGGAGGTGACGCAGAACTCCCCTGCGGCCCGCACTGG 1954 GGTGGTCAAGGAGGGGGACCAGATTGTGGGTGCCACCATCTACTTTGACAAGCTGCAGTC GGGTGAGGTGACCCAGCTGCTGAACACCATGG ADAM9 ADXCRPDRC.11545.C1_at AAAAGCCAAGTGTGCCCCAAAGATTGTTCCATGGAAGTGACATTCTACACAGGTGACAGA SEQ ID TTTGG NO: 1955 ADAM9 ADXCRPDRC.11545.C1_x_at GCTCAATGTCAAGTCATCTTTGGCACAAAAGCCAAGTGTGCCCCAAAGATTGTTCCATGG SEQ ID AAGTGACATTCTACACAGGTGACAGATTTGGCAATTGTGGTTACTCTGGCCATGAATACA NO: AGAAGTGTGCCACTGGGAATAGCTTTGTGTGGAAAGCTTCAGTGTGAGAATGTACAAGAG 1956 ATACCTGTATTTGGCATTGTGCCTGCTATTATTCAACACGCCTAGTCGAGGCACCCAATG TTGGG FLNA ADXCRPDRC.3227.C1_at AGAAGACAGGTGTGGCCGTCAACAAGCCAGCAGAGTTCACAGTGGATGCCAAGCACGGTG SEQ ID GCAAGGCCCCACTTCGGGTCCAAGTCCAGGACAATGAAGGCTGCCCTGTGGAGGCGTTGG NO: TCAAGGACAACGGCAATGGCACTTACAGCTGCTCCTACGTGCCCAGGAAGCCGGTGAAGC 1960 ACACAGCCATGGTGTCCTGGGGAGGCGTCAGCATCCCCAACAGCCCCTTCAGGGTGAATG TGGGAGCTGGCAGACACCCCAACAAGGTCAAAGTAT SVIL ADXCRPDRC.9920.C1_at CATGTCTATAAAGAAAGATGGCACTGTTGAAGAAAAGCGGGGAGGAAGATTGGAGAAACA SEQ ID GACTCAGCAGGAGGCAGGAGGGCGGCAGCGCCGCCACAGCCGCACACCCAGAAGCAGGCG NO: TCCCTCATCAGAAGCGT 1963 SVIL ADXCRPDRC.9920.C1_s_at TGGAAGCCCCAGGATTCTTCGGAACAGCCGCAGGAGAAGCTCTGCAAGAATCCATGTGCG SEQ ID ATGTTTGCTGCTGGAGAGATCAAACGCCGACAGGGGAGGGCCTTCTTGACTCACCCAGCA NO: A 1964 CAPN2 ADXCRPDRC.9976.C1_at ACGCGTACTCGGTCACCGGAGCCGAGGAGGTTGAAAGTAACGGAAGCCTACAGAAACTGA SEQ ID TCCGCATCCGAAATCCCTGGGGAGAAGTGGAGTGGACAGGGCGGTGGAATGACAACTGCC NO: CAAGCTGGAACACTATAGACCCAGAGGAGAGGGAAAGGCTGACCAGACGGCATGAAGATG 1965 GAGAATTCTGGATGTCTTTCAGTGACTTCCTGAGGCACTATTCCCGCCTGGAGATCTGTA ACCTGCCGAAGACCCAGCTTGAG CORO1C ADXCRPDRC.2786.C1_s_at AATCAAAGCAGTAGCCACATGGTGCTGGCTCCTTTGCAGCACAAACCTGGTCATTTTGAT SEQ ID GACTGTACAACAGGAAGACTTGAAAAATCACGTGGATTCATATTACCACCGCTCTCATTT NO: CATGGAGTCTTCTGATCAAAAAAGCTCACGTCGTATTTCTTCTTTTCCTTTCTCTTTTCT 1966 AGAAATTGGGTGTTTGTACCAGAATGGAATTTTGCTTCTCGGTTATCCTGTGCTTCAGAT GAT IL6ST ADXCRPDRC.11859.C1_s_at ACACTTCGAGCACTGTCCAGTATTCTACCGTGGTACACAGTGGCTACAGACACCAAGTTC SEQ ID CGTCAGTCCAAGTCTTCTCAAGATCCGAGTCTACCCAGCCCTTGTTAGATTCAGAGGAGT NO: GGCCAGAAGATCTACAATTAGTAGATCATGTAGATGGCGGTGATGGTATTTTTCCCAGGC 1971 AACAGTACTTCAAACAGTACTGCAGTCAGCATGAATCCAGTCCAGATATTTCACATTTTG AAAGGTCAAAGCAAGTTTCATCAGTCAATGAGG ADAMTS1 ADXCRPDRC.13363.C1_at AAAGGCATTGGCTACTTCTTCGTTTTGCAGCCCAAGGTTGTAGATGGTACTCCATGTAGC SEQ ID CCAGATTCCACCTCTGTCTGTGTGCAAGGACAGTGTGTAAAAGCTGGTTGTGATCGCATC NO: ATAGACTCCAAAAAGAAGTTTGATAAATGTGGTGTTTGCGGGGGAAATGGATCTACTTGT 1975 AAAAAAATGATCAGGATCAGTTACTAGTGCGAAACCTGGATATCATGATATCATCACAAT TCCAACTGGAGCCACCAACATCGAAGTG SPTBN1 ADXCRPDRC.13403.C1_at CAGTACATGTTTCTGCGGCAGCGGCTGCAGGCTCTGGACACTGGATGGAACGAGCTCCAC SEQ ID AAGATGTGGGAGAACAGACAAAATCTCCTATCCCAGTCACATGCCTACCAGCAGTTCCTC NO: AGAGACACGAAGCAAGCCGAAGCCTTTCTTAACAACCAGGTAAGGTTTGTTCCTGCCTTT 1979 GCTTCCTTTCGGTGAAAGCAGCGCTGGCTGCCTTTTGAAATGTTTTGGCTGGGGCAGCTG GTTTAAACCACACCCTGTATGGAATATATGGATAATTTAGAGACCGCGATG PTPRK ADXCRPDRC.14082.C1_s_at GGATTCACGGGTAGAGATTGGCTTCGGGCTGAGCTAGCAGTGAGCACCTTTTGGCCCAAT SEQ ID GAATATCAGGTAATATTTGAAGCTGAAGTCTCAGGAGGGAGAAGTGGTTATATTGCCATT NO: GATGACATCCAAGTACTGAGTTATCCTTGTGATAAATCTCCTCATTTCCTCCCGTCTAGG 1980 GGATGTAGAGGTGAATGCAGGGCAAAACGCTACATTTCAGTGCATTGCCACAGGGAGAGA TG MARCKS ADXCRPDRC.4423.C1_s_at CGTTACACCAACCCGAGGCTCTTTGTTTCCCCTCTTGGATCTGTTGAGTTTCTTTGTTGA SEQ ID AGAAGCCAGCATGGGTGCCCAGTTCTCCAAGACCGCAGCGAAGGGAGAAGCCGCCGCGGA NO: GAGGCCTGGGGAGGCGGCTGTGGCCTCGTCGCCTTCCAAAGCGAACGGACAGGAGAATGG 1981 CCACGTGAAGGTAAACGGCGAC ARID5B ADXCRPDRC.12803.C1_at ACCACCTGGCAATACAGTCCACTTTCTGGTTTCTTTTATTGTGGGAAGTAAATGGTCAAG SEQ ID CTGCTCAGGCAGTGAAAAGATGTGGAGAATGTCCGTTGTCATTCTTGCCACTGTATTCCA NO: TTTGCTACCGAGATATAACATTAAGGTGGACACATTTTCTAACTGTATTAATTAAAAGTC 1985 AATGGATACAGAGAGTGGATTTTCTCCCCAAGTCCCATCCCTGCTGAAGACCGCTTGGAT GACTCCCCAACCCACTGTGCCCCTCCCGCAACACTACCAGTAACAACAACGCG SGCE ADXCRPDRC.12912.C1_at TATTAAGTGTATACCCTATAATCGACATTCTC SEQ ID NO: 1991 SGCE ADXCRPDRC.12912.C1_s_at TCCACCCTGTGACTGGGGAAATCATTACCTCCTTTACACACTAGACAACTATGATAGCAC SEQ ID TAACATGCCATTGATGCAAACGCAGCAGAACTTGCCACATCAGACT NO: 1992 SGCE ADXCRPDRC.12912.C1_x_at GGGAAATCATTACCTCCTTTACACACTAGACAACTATGATAGCACTAACATGCCATTGAT SEQ ID GCAAACGCAGCAGAACTTGCCACATCAGACTCAGATTCCCCAACAGCAGACTTACAGGTA NO: AATGGTATCCCTGAAGAAAGAAAACTGACTGAAGCAATGAATTTATAATCAGACTCATAT 1993 AGCAGTTACATCACATTTCTTTTCTCTTCCTATAATGCATGAGCTTTTCTGTCATATGTT ATGCATGTTGCAGTATTAAGTGTATACCCTATAATCGACATTCTC FNDC3B ADXCRPDRC.13581.C1_at TTTATTCAAATCCAATAGCAAGCTCTGTTTTCTAATATAGTAAATGTCTTTATAGTAATA SEQ ID GTGAGTAATCATCAATTCTAAAGATAGAATTATTATTACAATAAACAAACTTTAGTCACA NO: TATTGGCAGTTT 1994 FNDC3B ADXCRPDRC.13581.C1_s_at TGGCTTTAGTGTCAAATGGGATCCCCCTAAGGACAATGGTGGTTCAGAAATCCTCAAGTA SEQ ID CTTGCTAGAGATTACTGATGGAAATTCTG NO: 1995 LOXL2 ADXCRPDRC.4590.C1_s_at ACCGTCTGCGACGACAAGTGGGACCTGGTGTCGGCCAGTGTGGTCTGCAGAGAGCTGGGC SEQ ID TTTGGGAGTGCCAAAGAGGCAGTCACTGGCTCCCGACTGGGGCAAGGGATCGGACCCATC NO: CACCTCAACGAGATCCAGTGCACAGGCAATGAGAAGTCCATTATAGACTGCAAGTTCAAT 1997 GCCGAGTCTCAGGGCTGCAACCACGAGGAGGATGCTGGTGTGAGATGCAACACCCCTGCC AT GJA1 ADXCRPDRC.13657.C1_at GCCTATGTCTCCTCCTGGGTACAAGCTGGTTACTGGCGACAGAAACAATTCTTCTTGCCG SEQ ID CAATTACAACAAGCAAGCAAGTGAGCAAAACTGGGCTAATTACAGTGCAGAACAAAATCG NO: AATGGGGCAGGCGGGAAGCACCATCTCTAACTCCCATGCACAGCCTTTTGATTTCCCCGA 2000 TGATAACCAGAATTCTAAAAAAACTAGCTGCTGGACATGAATTACAGCCACTAGCCACTT GTGGACCAGCGCCTTTCACAGTTCGTAGGGAT SPTBN1 ADXCRPDRC.15064.C1_at CTGCAGTTGAGTCCGCCACAAAAAAGCACGAGGCCATTGAGACAGACATTGCCGCATACG SEQ ID AGGAGCGTGTGCAGGCTGTGGTAGCCGTGGCCAGTTAGCTCGAGGCCGATAATTACCACG NO: ACATCAAGCGCATCACAGCGAGGAAGGACAATGTCATCCGGCTCTGGGAATACCTACTGG 2002 ACCTGCTCAGGGCCCGGAGACAGCGGCTCGAGATGAACCTGGGGCTGCAGAAGATATTCC AGGAAATGCTCTCCTTATGTGCTA LAMB1 ADXCRPDRC.14422.C1_at GTCAGCCTTGCCAGTGTCACAACAACATTGACACGACAGACCCAGAAGCCTGTGACAAGG SEQ ID AGACTGGGAGGTGTCTCAAGTGCCTGTACCACACGGAAGGGGAACACTGTCAGTTCTGCC NO: CGGTTTGGATACTATGGTGATGCCCTCCGGCAGGACTGTCGAAAGTGTGTCTGTAATTAC 2003 CTGGGCACCGTGCAAGAGCACTGTAACGGCTCTGACTGCCAGTGCGACAAAGCCCACTGG TCAGTGCTTGTGTCTTCCTAATGTGATCGGGCAGAAACTGTGACCGCTGTGTATTC TGFBR2 ADXCRPDRC.13821.C1_s_at ATGCCAGCCTTCTCAACCTTTGCAGAAATTACTAGAGAGGATTTGA SEQ ID NO: 2005 TGFBR2 ADXCRPDRC.13821.C1_x_at CAGCCTTCTCAACCTTTGCAGAAATTACTAGAGAGGATTTGAATGTGGGACACAAAGGTC SEQ ID CCATTTTGCACGTTAGAAAATTTGTGTCCACAAGGACAAGAACAAAGTANTGAGCTTTAA NO: AGCTCCATAGGAAACTTGTTAAATCAACAAGAGAAGTGTTAATGCTGCAAGTANTCCTCN 2006 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCAAGCCAAAATAGGAATATTAAGAN GAGGGGACTGGGTANGTGAGAATATCAGCTCCGGTTTGGGATGGTG FAM50A ADXCRPDRC.6370.C1_at ACTGCTGCATGGTGTTGCCCTTTCTCATCTTGACTGTCCGCCGGTGCCCAGAGCCATCCC SEQ ID AGTAGCTGAAGGTGATCTCGATCTCCTCACTCTTGATCTTCTCCTGCTTGGCTTCCCACT NO: CCTGCCGCAGCTCTTCCCGAAGCCGATTCTCCTCCTCCTCACGGTCTCGATCAGGCAAGA 2010 AGCTTGTGTCAACGTCTGGGT CD59 ADXCRPDRC.15392.C1_at ATCTTTCCCCTTGCGGTACTAATCTATTGGCGCACAAGGAGGGCGTCACAGTGCT SEQ ID NO: 2011 CD59 ADXCRPDRC.15392.C1_s_at GTAGTGAGCTGCCTTTCTGTGATCGGTTTCCCTAGGGATGTTGCTGTTCCCCTCCTTGCT SEQ ID ATTCGCAGCTACATACAACGTGGCCAACCCCAGTAGGCTGATCCTATATATGATCAGTGC NO: TGGTGCTGACTCTCAATAGCCCCAC 2012 CCND1 ADXCRPDRC.16054.C1_at GTAGTGACCTGTTTATGAGATGCTGGTTTTCTACCCAACGGCCCTGCAACCAGCTCACGT SEQ ID CCAGGTTCAACCCACAGCTACTTGGTTTGTGTTCTTCTTCATATTCTAAAACCATTCCAT NO: TTCCAAGCACTTTCAGTCCAATAGGTGTAGGAAATAGCGCTGTTTTTGTTGTGTGTGCAG 2013 GGAGGGCAGTTTTCTAATGGAATGGTTTGGGAATATCCATGTACTTGTTTGCAAGCAGGA CTTTGAGGCAAGTG PPP4R1 ADXCRPDRC.6469.C1_s_at GAATATCTTTATCAACTTCAGGAGTTTTTGGTGACAGATAATAGTAGAAATTGGCGGTTT SEQ ID CGAGCTGAACTGGCTGAACAGCTGATTTTACTTCTAGAGTTATATAGTCCCAGAGATGTT NO: TATGACTATTTACGTCCCATTGCTCTGAATCTGTGTGCCGACAAAGTTTCTTCTGTTCGT 2014 TGGATTTCCTACAAGTTGGTCAGCGAGATGGTGAAGAAGCTGCACGCGGCAACACCACCA ACGTTCGGAGTGGACCTCATC CRIM1 ADXCRPDRC.15616.C1_s_at AGTGCAGACCCATAATCTGTGACAAGTATTGTCCACTTGGATTGCTGAAGAATAAGCACG SEQ ID GCTGTGACATCTGTCGCTGTAAGAAATGTCCAGAGCTCTCATGCAGTAAGATCTGCCCCT NO: TGGGTTTCCAGCAGGACAGTCACGGCTGTCTTATCTGCAAGTGCAGAGAGGCCTCTGCTT 2018 CAGCTGNGCCACCCATCCTGTCGGACACTTGTCTCACCGTGGATGGTCATCATCATAAAA ATGAGGAGAGCTGGCACGATGNGTGCCGNGAATGCTACTGTCTCAATGGACGGG FLNB ADXCRPDRC.15647.C1_at CGAACTCAACCCGAAGAAAGCCAGGGCCTATGGCAGAGGAATCGAGCCCACTGGAAACAT SEQ ID GGTGAAGCAGCCAGCCAAGTTCACTGTGGACACCATCAGCGCCGGGCAAGGAGACGTGAT NO: GGTGTTTGTTGAGGACCCAGAAGGGAACAAAGAGGAGGCACGAGTGACCCCTGACAGTGA 2019 CAAGAACAAGACATACTCTGTGGAGTATCTGCCCAAGGTCACCGGGCTACTACAAAGTCA CAGTCCTCTTGCAGGACAGCACATCTCCGAA IGFBP3 ADXCRPDRC.17075.C1_at TTTTCTTGTCGGCTTCCTATCAGAATATTCAGAG SEQ ID NO: 2020 IGFBP3 ADXCRPDRC.17075.C1_s_at TTGAATGGTAAACTTGAGCATCTTTTCACTTTCCAGTAGTCAGCAAAGAGCAGTTTGAAT SEQ ID TTTCTTGTCGGCTTCCTATCAGAATATTCAGAGACTCGAGCACAGCACCCAGACTTCATG NO: CGCCCGTGGAATGCTCACCACATGTTGGTCGAAGCGGCCGACCACTGACTTTGTGACTTA 2021 GGCGGCTGTGTTGCCTATGTAGA CASK ADXCRPDRC.17222.C1_at TTGAAATCGTAAAGCGAGCTGACGCTGGTTTTGTGTACAGTGAAGCTGTAGCCAGCCATT SEQ ID ATATGAGACAGATACTGGAAGCTCTACGCTACTGCCATGATAATAACATAATTCACAGGG NO: ATGTGAAGCCCCACTGTGTTCTCCTTGCCTCAAAAGAAAACTCGGCACCTGTTAAACTTG 2029 GAGGCTTTGGGTAGCTATTCATTAGGGGAGTCTGGACTTGTAGCTGGGAGACGTGTTGGA ACACC SYNJ2 ADXCRPDRC.8240.C1_at TCGGCTTCACTCTTGACAGCGCTTGCTTTGTATTTCCTGGGTTGCTCTTCTGTCCCACAT SEQ ID TGGCTCATTGCCATCTGTCCCTTGTCCATGCTTCCTTACAAAGTGGACCTTTTTCCTCCG NO: CCTCTTCCCTGTTCAGATGCTCCTCGACTTAAAATGGGGTTACATCCCAATAAACCCATC 2030 GTAAGTTGAAAAATAGCGTGTCAAAACTGCATCTCATACACCTAACCTAGCAAACGTCAT GGTCTCGCTGACCTTGAACACACTCAGAACACATACATTAGCCTACGGCT MARCKS ADXCRPDRC.8271.C1_s_at GAAGGCGAGGCTGCCGAGCCCGGCTCGCCCACGGCCGCGGAGGGAGAGGCCGCGTCGGCC SEQ ID GCCTCCTCGACTTCTTCGCCCAAGGCCGAGGACGGGGCCACGCCCTCGCCCAGCAACGAG NO: ACCCCGNNNNNNNNNNNGAAGCGCTTTTCCTTCAAGAAGTCTTTCAAGCTGAGCGGCTTC 2032 TCCTTCAAGAAGAACAAGAAGGAGGCTGGAGAAGGCGGTGAGGCTGAGGCGCCC TMEM158 ADXCRPDRC.7689.C1_s_at GATTAAATTGCTATTGCTGTAGTAAGAGAAGCTCTTTGTATCTGAACATAGTTGTATTTG SEQ ID AAATTTGTGGTTTTTTAATTTATTTAAAATTGGGGGGAGGGCATGGGAAGGATTTAACAC NO: CGATATATTGTTACCGCTGAAAATGAACTTTATGAACCTTTTCCAAGTTGATCTATCCAG 2034 TGACGTGGCCTGGTGGGCGTTTCTTCTTGTACT FHL1 ADXCRPDRC.10038.C1_at AGTATTACTCAAATAAGGGCACACAGTGATCATATTAGCATTTAGCAAAAAGCAACCCTG SEQ ID CAGCAAAGTGAATTTCTGTCCGGCTGCAATTTAAAAATGAAAACTTAGGTAGATTGACTC NO: TTCTGCATGTTTCTCATAGAGCAGAAAAGTGCTAATCATTTAGCCACTTAGTGATGTAAG 2035 CAAGAAGCATAGGAGATAAAACCCCCACTGAGATGCCTCTCATGCCTCAGCTGGGACCCA GCTTGAGACCCGCGA EGFR ADXCRAD_CV574329_s_at GGAAGCCAAGCCAAATGGCATCTTTAAGGGCTCCACAGCTGAAAATGCAGAATACCTAAG SEQ ID GGTCGCGCCACAAAGCAGTGAATTTATTGGAGCATGACCACGGAGGATAGTATGAGCCCT NO: AAAAATCCAGACTCTTTCGATACCCAGGACCAAGCCACAGCAGGTCCTCCATCCCAACAG 2037 CCATGCCCGCATTAGCTCTTAGACCCACAGACTGGTTTTGCAACGTTTACACCGACTAGC CAGGAAGTACTTCCACCTCGGGCACATTT LPP ADXCRPDRC.9098.C1_s_at AGGAGACTGTCCGTATTGTGGCTTTGGATCGAGATTTCCATGTTCACTGCTACCGATGCG SEQ ID AGGATTGCGGTGGTCTCCTGTCTGAAGGAGATAACCAAGGCTGCTACCCCTTGGATGGGC NO: ACATCCTCTGCAAGACCTGCAACTCTGCCCGCATCAGGGTGTTGACCGCCAAGGCGAGCA 2040 CTGACCTTTAGATTCAGTCACCTGTTCAGCCG YPEL5 ADXCRPDRC.17470.C1_s_at GAATCTGTGCCCAGCGCTAAAGGCTCAGTGTTAGCATGGCTTGTGCTGGCCGGTGTGCCA SEQ ID TATTCTTGTTGGAGATGAACCGTAGCACCAGAGCCCATTCTTCCTTGTCAGTCTTGGCCC NO: AAAGATGTCACCATTCCTAGTTATTTGTCACCACATAATTGGTGTTGATTGGAAACTTTT 2041 TCTGAGATGGGACAGAACTGCTGGGTTGTCTTTTTCCATGTAACT ZFP36L1 ADXCRPDRC.7802.C1_at GGAAGTTTCAAGGAGACCGCCAGCTCAAGATGGAAACCGCGGCCCGGGCGCTAAGAACGG SEQ ID GCTTCAGCTCCCGCTGGCAAAAAGAGAAAGTCGAGCCCGCCTTCCTGCCCAACAAAAAAC NO: AACAACATGACAACAAGAACCCCGGAGGGAGTGGAATGAGTGACGTCACAGCCGCGCTCT 2042 GAGGCTGACAAAGGAGGGGGCGCGCCCCTCCCGCTCTGCGCCCGCGCGGCCCCGGAGAGG GGGCGCCTGAAGCGCCGGGTAGGGAAGTCAGCCGACTTGAAACTTTTCCTCTT JUN ADXCRPDRC.3805.C1_s_at AACTTGTGCGCGCAGCCCAAACTAACCTCACGTGAAGTGACGGACTGTTCTATGACTGCA SEQ ID AAGATGGAAACGACCTTCTATGACGATGCCCTCAACGCCTCGTTCCTCCCGTCCGAGAGC NO: GGACCTTATGGCTACAGTAACCCCAAGATCCTGAAA 2045 SCRN1 ADXCRAD_CK001870_at AGATGGAAATGCTATTGGCGGGAATATATAAAAAAAAAGAATCTTCTGTTCTGCATGG SEQ ID NO: 2046 SCRN1 ADXCRAD_CK001870_s_at GAGCAGCAGGTCATGTGCACATGCCGTTGCAGCACAAGCTTATGCTTCCCGTAGCCGTGG SEQ ID CTTTTCATTCTGCACAGTCCCAGGTCCCAGCTCCCCTCTTATGGTTTCTGTCATAATGTG NO: CTTTATCTGATTGACTCCAAACATCCCGAAATGTCACCTGCAGATTTCTCGTGGGAACCA 2047 ATATGTACATGTT FLNA ADXCRPDRC.3150.C3_s_at GTCTCGTCAGCAACCACAGCCTCCACGAGACATCATCAGTGTTTGTAGACTCTCTGACCA SEQ ID AGGCCACCTGTGCCCCACAGCATGGGGCCCCGGGTCCTGGGCCTGCTGACGCCAGCAAGG NO: TGGTGGCCAAGGGCCTGGGGCTGAGCAAGGCCTACGTAGGCCAGAAGAGCAGCTTCACAG 2048 TAGACTGCAGCAAAGC FLNA ADXCRPDRC.16964.C1_at AAAAGTGACCGCCAATAACGACAAGAACCGCACCTTCTCCGTCTGGTACGTCCCCGAGTT SEQ ID GACGGGGACTCATAAGGTTACTGTGCTCTTTGCTGGCCAGCACATCGCCAAGAGCCCCTT NO: CGAGGTGTACGTGGATAAGTCACAGGGTGACGCCAGCAAAAGTGACAGCCCAAGGTCCCG 2051 GCCTGGAGCCCAGTGGCAACATCGCCAACAAGACCACCTACTTTGAGATCTCCACGGCAG GAGCTGGCAC SPTBN1 ADXCRPDRC.1211.C4_at CAGGGCTTGTAACCTTACCCGTCTGTAGAGAACTTCTGGGCGGAGGCATTGACACCTCTC SEQ ID ACCCGCTCTGCCTGGATGCCAATGTCTGCTTCAACCAGGGTGTGCTTCTGTAACAGGTCT NO: TCCACACCAAGTAAGTGTTTGCCATAGTCTTGAGACAATACTAGCACCTTCATTTCATCC 2052 ATCCAGTCCATAATGTAGAGCATTTCCTGGAATATCTTCTGAAGCCCCAGGTTAATCTGA ACCGCTGGTTTCCGGGC SPTBN1 ADXCRPDRC.5087.C2_s_at GAGAGGATCATTTACATCCGGGAGCAGTGGGCCAACCTAGAGCAGCTCTCGGCCATTCGG SEQ ID AAGAAGCGCCTGGAGGAGGCCTCCCTGCTGCACCAGTTCCAGGCAGATGCTGATGACATT NO: GATGCCTGGATGCTGGACATCCTCAAGATTGTCTCCAGCAGCGACGTGGGCCACGATGAG 2055 TATTCCACACAGTCTCTGGTCAAGAAACACAAGGACGTGGCGGAAGAGATCGCCAATTAC AGGCCCACCCTTGACACGCTGCACGAACAAGCCAG ATP2B4 ADXCRPDRC.5728.C1_s_at TGGAAGGAGATGAGCTCCCATAACTGAATTGGCCTTTGGTTCATGTTTTCTCCCCATATG SEQ ID TATATATGCCATATGTGAATATGCCATATATATGTGCCCACAAATCTATCTACGTTGTTC NO: TTTTCAAATTAGCACGCAGATAGGAATTTTGAGTTTCTTCTTCTTTTAGTAACTAGTATA 2056 ACAAGCACTGGTATTTT LAMB1 ADXCRPDRC.10237.C2_at CTGTGGTGGTCTGGTTACTGTTGCACACAACGCCTGGCAGAAAGCCATGGACTTGGACCA SEQ ID AGATGTCCTGAGTGCCCTGGCTGAAGTGGAACAGCTCTCCAAGATGGTCTCTGAAGCAAA NO: ACTGAGGGCAGATGAGGCAAAACAAAGTGCCTGAAAGACATTCTGTTGAAGACAAATGCT 2057 ACCAAAGAAAAAATGGACAAGAGCAATGAGGAGCTGAGAAATCTAATCAAGCAACATCAG AAACTTTTTTGACCCAGGATGTAGGAACTGGTCTCTGGCCCAGAGA TGFBR2 ADXCRPDRC.12527.C1_s_at AGAGCTGCTGCCCATTGAGCTGGACACCCTGGTGGGGAAAGGTCGCTTTGCTGAGGTCTA SEQ ID TAAGGCCAAGCTGAAGCAGAACACTTCAGAGCAGTTTGAGACAGTGGCAGTCAAGATCTT NO: TCCCTATGAGGAGTATGCCTCTTGGAAGACAGAGAAGGACATCTTCTCAGACATCAATCT 2059 GAAGCATGAGAACATACTCCAGTTCCTGACGGCTGAGGAG PDLIM7 ADXCRSS.Hs#S5951004_s_at TGGCAGCACCTGCTTACTTACCACTCATGGTGCAAGATGACACTTCAGCCTCCGCCAAAA SEQ ID TGCTCACCTTCCAGCCAGCAGGAAGTCGGAAGGAGAAGAAAGGGGACAGAGCCCCATGGC NO: GTCCATCCTTAGAGGATGCTGCCACCTGAACCTCTGCTTT 2060 LPP ADXCRSS.Hs#S1294625_at TGAAGGTCTTCAGCAAAAATTTGGACTGTAAACACAGCTTGGCATTATCAGCATTCTGTT SEQ ID AAGTTCAAAGAAGAGATAGTTACAACAAATACAGCTTGCTTTATTTCTGAAACAAAACTG NO: TGCACATATTTGTGGCCATACTACTAATTAACCTGTAGATTGTTCCTTTCATCTATTCAG 2063 CGTGTTTTTCTGCCCCCTGTTACAACAGTGTTGGGTTACTTTTCCCATATGGACTATATT TAAACAGTTCCCTTATAGGCATTAGAG NT5E ADXCRSS.Hs#S1299958_at ATTGAACAGAGAATCTACCCCAAAGCTGTGAGCTTAATTACTCTCAAGCTCCGGGGTCAA SEQ ID AGAGATCTGGTGTCCATTCTTATCACGTCTCCCTTTTTGCGGGGATGGTGCCTGTTAATT NO: TATTCAGCTTCTTCGACGCGGTTTCCCTTTCAATAAGATTGAGATAAAGCATTTTTCGAA 2064 AGATCTAGATTGAGATAAAGCATTCTTTGAAAGATCTAGCAGTAAA CRIM1 ADXCRSS.Hs#S1805720_s_at GAAGATGTTTGTCTGAGCATCCCATGAGGTAAGCAGCCCCATGGAAGGACCAGCTGCATC SEQ ID CAGCAAAGGGCTCCAGGTCCCTGACGTAGTTGACGGTGATGGCAGAAGTAAATCTTTGTA NO: TTCTTGCAGAGACTTTGTTTTTCTGTCATTCCACAGCAGCTCAGCATACTCTAATAAACG 2065 TCCTCCTCTTCCCCTTCGTAGCATTCTGGGACTAATCAGGGTTTCATCTGCTCACATATT GTAGCGATGGGTTC CD44 ADXCRSS.Hs#S1228681_at TGCATTCCATTCCTTGTGTCTTAAAAGCAGACTGCAGTGTAGCTGAAGCAACCTTCTATT SEQ ID CATGCCAAAGTGCTTTATTCTGTGACTATACCTTGTATTGAGCTCTAAAACCTCAGAGAG NO: CTTTAAACTGGTTTTGCCTTTATAGAAAGGTTAAGTCCATTTGTGCATTACAGCTTTTAT 2068 TCTGTGTGTGTGTGCATACTTAAATTAAAATGGAAATTTATTTGTTAGGTTAGTTTCTCC CAGAATTGCTCCTGGCAAAGAG CD55 ADXCRSS.Hs#S2874822_at GTAAAAAGGAGATAGGTCACATCATCTAAAGAATTAAAACAGACAATTTAATAACAGCAT SEQ ID TAAATTAATAGTTTTCTTATTAATGGGAAAAACGGACAGGCATTAGGGCAGCTTAGAAAT NO: AACTCAAGTTTGTATAAATTCCACAACTAGT 2073 CD55 ADXCRSS.Hs#S2874822_x_at TATTTTTCTACAAGACTGACTCATTTAGTGAGTTAAAGAATATTTACATGCTTTAACTTA SEQ ID TAATAGGCTTAAGTAATATTCTTAATTTAAGTAGAAAAATTGTAGAGGGTAAAAAGGAGA NO: TAGGTCACATCATCTAAAGAATTAAAACAGACAATTTAATAACAGCATTAAATTAATAGT 2074 TTTCTTATTAATGGGAAAAACGGACAGGCATTAGGGCAGCTTAGAAATAACTCAAGTTTG TATAAATTCCACAACTAGTTTTCTGAACAGT CD55 ADXCRSS.Hs#S2948409_at TTGGTGAATATCCTTGTACTGTATATTTTCATATTATTGGAGGTATATCTTCAGAGTTCA SEQ ID TTTCTAGATGTGAGACTGGTGGATCAAAGGGTAAATGCGTATGTGTGGGGTTTTTTTTAG NO: ATATTGGAAAATTCCCCTATAAAATGGCCGTATCAGTTTGCATTCCCACCAATAATATAT 2075 AAAAACATCTGATTTTCCACAGCCACACCAATAGGAAGTCTGGTCACATGAAAACCACAT TCTCAACATAACTAGAAGACAAAGCACCTACTTCAAATTGCCTATAAG RCN1 ADXCRSS.Hs#S1371296_at AGCTCCACAGCTGGCCTAGGTTTCACAAATTTCCCACTGAACTCCACTGAGGTACCCTAA SEQ ID ATGCTAGCCCAGAGCAAACTTCAGGCTGGGAACCCACTTTTGTCATCTCTAGACCAGATG NO: GTCCCAAACCAGGACAGCATCCCAGTGGGGAACTTCAAAAACACCTCCAAGCTATCCCCA 2077 GTGTTTAAAAAAGTTTCACCCTTGTAGTCCATTTATCTGGGAGGAGGTCATACAGGCTAA CTCTAGATTTCTTTCTTTGTTTTGGGCTGGAATTCTAACAGCTTC LAMB1 ADXCRSS.Hs#S1582622_at CAGAAACCCTGGGAGCAGCATGGTGGAGTAGAAAAGTATGAGCTGGGCATTAGACGGGCT SEQ ID GGGCTTTGAGTTTTGGCTTTGTTGCTTGTGTACTTCAGTTAGGATTTCTTAGTTGCAAGC NO: AGCCCAAAACAGCTCTGGCCAGCCTCACCATGCCTTGGCTATGATAAAAGCCATAAAGAG 2078 GAATGGCACCGCTCCTTGATGCTTGTTGGCAGCAAGTACCTGGAATTATGCTCCCACCAA GACTGCATGCATGG PHACTR2 ADXCRSS.Hs#S1584468_s_at AGAAGACCAGCGACAAATTTAGAGAAACCTCGGCAGTATTAGAAAGGAAGATATCCACAC SEQ ID GACAAAGTAGAGAGGAGCTGATAAGAAGGCGAGTGCTTAAGGAATTGCCTGATCAAGATG NO: GAGATGTAACAGTTAACTTTGAAAATTCAAACGGGCACATGATACCCATCGGAGAGGAAT 2079 CTACCCGAGAGGAAAATGTAGTAAAGTCTGAAGAAGGTAATGGCTCTGTATCTGAAAAAA CACCACCTCTGG COL5A2 ADXCRSS.Hs#S11048343_at GAGGGCACACCTGAGAAGTCATTCCGCTACATGAACTCTGTTATTTTCCTTATCCCTTAT SEQ ID TTTTTCCTCCCCTTCACATCCAAATCTTTCAAGTCCGCCATCAAGTCTGATGTGCATCCT NO: CTTTGAAACCTTTTTGAACATCATAGACATATTTTTTCTCTTTTCTCTAAAAGGTAGCAC 2083 TTCCTCTTTCTTTAACACATTTAGCACACAATAAATCCTTTTATTTATTGCCCACTGTTT TCTAAATAACATTTATTGTAAATGTCATTGATTATTTAGTTATATCATATGCTCCTTGA SEPT7 ADXCRSS.Hs#S1914581_at GGGCCCAGAGTTTGCTCCCAGGGAATCTAATGAACCACCTGGAATCAAACATTTGGAGAG SEQ ID AAGGCCAGTCACTTTTATCGGAACGTCAGATGGTCATGGACCCTCAAGAATGATTGAAGA NO: AATTTGTAAGCCCAGTTAAAACATCCACAGTCTTCTTTCCTCAGTGCAAAAGTTGCCCTT 2088 TTTGATATCTCATATTTAGAGTAAAAAAATTTCGTTAATAAGAGATCCTCT ZDHHC7 ADXCRSS.Hs#S1917518_at TGTATTATATGATCTGAACCCTGGGGAACATCTATAAAGTGGGGACGTCCCAGAGACCTG SEQ ID CGGCCTTTTCCACCTGAGAAGGTGCCTCAGCCGATTCAAATAAGAGGATGTTCCTGTGTT NO: CCCTTCCCAAGAGGATCTACCAGGAACTTCAGCGACAGCTGTTCCCAGGACACCCTTTAT 2089 TTTATGCTGGGAGGCATCGTCCTCCGTGGACCACTCATTTGGGGTTAGCTGCCTGTAGAA CCGATTCCTGGGACAAACCCGTTGTCACGTATCCACAGAATGG FNDC3B ADXCRSS.Hs#S1917639_at ACGATCAACGGTGTGACTGTTGGGTGGTTGAATTGAAACTTAGGAGTGTATGATGTTCAT SEQ ID ATGTTCCCACTTGATCTTTCTCAGGAGTGTTTGTACATACAGCCTCCCTGTCTCCCCTTC NO: CTCCATCCCTTCCCAGTCATTTCTAGTAACCACTGAACACTGTATGAGGTGGAAAGTCCA 2090 TCATGTAGTAGAGAAAAAGATTCAAGCATCTCACCTAAAGTTGTCTATGAAGTTTTCAAA AGCAAATATAATGATCTCCTTGTGCCAGTGGACTTCTTTGGTTTAT ZCCHC14 ADXCRSS.Hs#S1918747_at AATCGGCTAGCAGGCTTTGTTTCTGCAGGCACCACAAACTCTATTCCAGGAGTCTTCTTG SEQ ID GGACACCCTATTATGAACAAGGCATCGCTGCTTCAGAGCCAGGGACCCCATCTCTTACTG NO: TCGGCCATGCAACAAAAGATCAGACCAGAAAGGGCTCACCTGGATTGATCACAGAAGACA 2091 TTTAGGCTAAAAAGTTTCAGATTTACCTCCCACTGCAGCTATGACCAGACCCTCATCCCC TAGGCACCTGGTATCTGCCCAACTGAACTTCAC PPP4R1 ADXCRSS.Hs#S1919443_at CCAGGATTCTTAAATGTTACCTTCTCTAACTAATATATATGGCTTGACTATCTAGACTTA SEQ ID TACTTAACAGGTATTTACATCTTTGAACACAGAACAGCTGATGGAGAAAGAAGCATTATA NO: AATAATATACATAAACTCAGTTGGTACAGATAATCCGTAATTGTTAATGTTGAACTTGTC 2094 TAAATGCTATATGTAATATCTTGCATCAGTAAGATAAAGTAATTATCCTTTCATATCGTT TTTTCCCACCAAATAAACAATAAAGGACCGAAATATCAAGGG PPP4R1 ADXCRSS.Hs#S1919443_x_at GAAGTCCCAGGATTCTTAAATGTTACCTTCTCTAACTAATATATATGGCTTGACTATCTA SEQ ID GACTTATACTTAACAGGTATTTACATCTTTGAACACAGAACAGCTGATGGAGAAAGAAGC NO: ATTATAAATAATATACATAAACTCAGTTGGTACAGATAATCCGTAATTGTTAATGTTGAA 2095 CTTGTCTAAATGCTATATGTAATATCTTGCATCAGTAAGATAAAGTAATTATCCTTTCAT ATCGTTTTTTCCCACCAAATA COL4A2 ADXCRSS.Hs#S2731998_at TGAAATATACAAGTGAGTTCACCAAACTCATAAAAATGTCCTTAAAATGATAAAATGGAG SEQ ID AACTTGGGGGTCCCAACAAAGAGGAATTAAGGCCTGGATCATGATTACCTCTGTTTTCCA NO: TGTGACTTTGAAAGCAGCAGGGCTGGAGCCAAGTTGGCCCTGCTCCCTCCTAGGGACAGC 2098 AGGGTTGATGTCCACCTCCATTTCCATTTGCTTCTGTCCAGCCGGCAGGCTTGGCGGCCC CTCCTGGCTCTGGAGCTTTAATACTTTCTTATTCTATCCGATCAGCG LPP ADXCRSS.Hs#S1921588_at GATTCAGTGGGCAACTGTGGCAATAGTTCTTGGCTAACCTGGTCACTATGGAAGTTCTTT SEQ ID CCGTGGAAAAAGATTCTCCATCCTTCAATTTGAGATAAGATTTACTAATTGAGACCTCAT NO: TTGTATCTGATTTTAATCTTTGCATCATTTTAGTTTTAATAAACTAACTTTCCAACTTAC 2104 CAGATTTTCGGGTTGACAAAGACCATTATTTAGAGAAACACAGGCAAAGGAAAGTCTAAA AGCTTTGGCTGGAATTTCAACTGCTTCTGGTCCAGAAT CREB3L1 ADXCRSS.Hs#S2306153_at AAGCAACGTTGCACATCAGCTCCACTTGGACATCATGAGTATCACGCTGAGCATGAGCTT SEQ ID GCACCAGCCCTGACATTGTGGGACATGTGACTGCCAGGCGCTTGTGTCTCAGCTATGACA NO: TCAGAAGCCCCTCTGCAGGGTCAGAACGACAGTTGACATCTGGGTAGCCAATTCCTGGGT 2107 GCTGCCTCATCTAGACACCACAGAGGCCCAGCTCCTTTACCAGCCTCGGCCTTGGCATAG ACATCA LPP ADXCRSS.Hs#S2732094_at CAAAAATTCCTGCATATACCCACTCAGGAAATATTTTCCCAAATCTTCTCCATCTCAACT SEQ ID CTGTGAGGCATTGGAAGAGGTGCTTTTAGGCATAGACTGATGCACTCTATATATGATGTC NO: TCGCCCTCCAGGGCAGCACACAGTTTAGTGAGGTAAATGTCTCATGAATATTCCACAAGA 2109 TCCACCTTGATAATGCTCTAACGTTACTCATAGAGGGCTGAATGTGGAAAGATGCTTTCG TCTGGTGGCAAA FNDC3B ADXCRSS.Hs#S1927775_at AGGACTTTGGTAACAGAACATTCTGTCACCATTAACTTTTGCTTGACATTGGATTATTTC SEQ ID TAAATACAGTTTGGCTGTCTTCTGATCGGACATTTTCAGAGGAAATGAAGTTAGGTTAAA NO: CAAATACTACGTGAAAGGCTACATTTGATTTTGACAGCCAAGAATGTTTCCTGGGTATGG 2110 AGTTTTATGAAGAATCTCCTATTTGCTCTGGTTAATTTGATATTGCATTGCCCATAGTTA CAGAGTACAGTCCCCATCTGTACATCACCTACCTATTTC RYBP ADXCRSS.Hs#S1924603_at TCCATAGTATTTTAAGCTCCGTAAGGAACAGGGACCTGGTCTGTCTTTATACCACTGTAC SEQ ID ACCAAGAGCGCAAATGGCTGTGTGCTCAATAAAAACTTGTCAAATGACCACAACTACCCA NO: GGTAATTTACTTTAAGGTCACCAAGTACACATAAGATCAAGTCACCACCAATAAATCAGT 2113 AAGTCCAATGAAACAGTAAACACAAAATAAATTATTACTCTGTTCCTGGGTAAAATGATC TTAAATTGTACCAGCTTTCAGCTTGGAAGGTTTGA PLAUR ADXCRSS.Hs#S1925412_at ATGGATGAATGTGTGGACGAATAGATAGATGAAAGAATGGATGGATGGATAAATGGGTAG SEQ ID ATGAATGGAATGGGTGGATGGATAGGTAATTGTACTGATGGGAGAAGACTTGTCTTGCTC NO: CCATCAGCCCCCTGAGTAGCTGGGGTTATAGGTGCACGCCACCACACCCAGCTAATTTTT 2114 GTAATTTTTTGTAGAGACAGGGTTTCACCATGGTGGCCAGGCTTGCTCTCATACTCCTGA CCTCAGTGGTCTCCTCCTCAC PLAUR ADXCRSS.Hs#S1925412_x_at ATGGATGAATGTGTGGACGAATAGATAGATGAAAGAATGGATGGATGGATAAATGGGTAG SEQ ID ATGAATGGAATGGGTGGATGGATAGGTAATTGTACTGATGGGAGAAGACTTGTCTTGCTC NO: CCATCAGCCCCCTGAGTAGCTGGGGTTATAGGTGCACGCCACCACACCCAGCTAATTTTT 2115 GTAATTTTTTGTAGAGACAGGGTTTCACCATGGTGGCCAGGCTTGCTCTCATACTCCTGA CCTCAGTGGTCTCCT FLNB ADXCRSS.Hs#S1926534_at GTCAGGCTCACATCTGAAACATGTTTAAACAGCTAATGGAGCTGAGCAACTAAAAGCTAA SEQ ID ATGAGTTTCTATGCTGGGCTGCCTATGAGACAAGGTCACAATAGTTACCAAGTATAATAA NO: CTATTATTAAGAGACCCTGGCAGTCCCAATAAAAGTAGGTCCTAAAAACTTTTAAGAGAC 2117 AGAAAGTGGCTGGAACACCTCCATGCCGTGGTTGACCAAACATATTTCTAGCACAAGGGA GACTGCAAACCACAATGAGACTCAATGAGACCTTCATTTAATGTGGGACACAG LPP ADXCRSS.Hs#S1908923_at TGCCCTTTTTTGTGCCTGGGCTTCATCCTTGGAATGTTTTACCTCATGGGCCATGAGACG SEQ ID GCTGCCTGCTGAAACCCAAACTATAGATATCCCTGTTCCCATTTAGGGGAAAGAGCCTGG NO: TTTGCTATATTCTCATAGGCTTGGCTGACTGTATATTTCTGAACCAGTCATTGAAGCCAA 2119 GAGAATGGGATTATGGTAATATGAACCACTATTCTCCTGAAACTGAATTTGGACATAGTC CCATCCAAACCTCATGGTACTTACACAGTGG NR3C1 ADXCRSS.Hs#S1907985_at GGGACTAATGTAGCCTTGCTTCTGAGATGTGGCCCCTAGGTCTCTACTGAATGCCCGGCA SEQ ID TATTTAATTAGATCTTTCTTTCCTCTATGGCCTCAAGGGATTTCACCCTAAGTATGCACA NO: AATTTTTATTCAGCCGAAGACTGTACAGATTTCTGGAGGCCTTTCTTTGTGTACCTCCTT 2121 CGTTTCCAGTAGTCTGACCCATAAATTGTACAGATTTCTG LAMB1 ADXCRSS.Hs#S1908684_at TCTTGGGAAGACTCATAGGCCTTTTCTAGTAGAATCTTACCTAGCATCAGCCCTCATAAA SEQ ID TTTGCTGATGTAATTTTAAGTTATACTTTCTAGCTGCTGGAACACGCATGAGCGAGTGTC NO: TATCCTATTTCCTCAAAGTTGCTCAACTTGCTTAAGAAATACATAACTGCATATTGGACA 2122 TCAGAAGTGCTTGGTTCTAGCTGGGGGAAAAGGATGGTTAATTCCCCCCTAAAGCATCAT TGTTTTGCAATCGAGTGAATCGGATGGATTCTCCTTCCCAG LPP ADXCRSS.Hs#S1910599_at GAAGACAACAACAGGTAAACGAGAAAATCCTTGGAAAAGAACACCGTTAATTTACAATAG SEQ ID TATATGTCTCTCTCTGGCCAACGTACTTTGTTTCATGACACTACTGGCATCATCCATCCC NO: AAATACTTTCGGTCGCTGTGTGTTTCAGACTCTGAAAAACCTTCAAATAACACAATAAAA 2123 CCTGCTCCTCTTTTCCTTTAATCTTACATAAAGGCAGTTCTCTTAAGTCTATAGTCAAAG C FNDC3B ADXCRSS.Hs#S1910605_at TAAATGAAGACACCTAACGGTTTGAAACCTTCTGGCTCTGAGGAGAGGAAGAGGGTCCCC SEQ ID AGATACAGGTTTCAATTCCTTACCATTTAGTCTGGTTCCATTGATCAGGGGTTCAGTTTT NO: CTCACCTTAAAATAAGAGGATTAGAACAGATAATTTCTAAAATTATTTTTACCACCCCTT 2124 TTCTCTTTTCTTTCTTTAATTCCTGTGGCGTTCTCTGCAGTTTATATGTCCCTAATTTTA TG LDLR ADXCRSS.Hs#S1911522_at TTGGCAGAACTTTCTGGCTTTTCCCCCTTCATGTTACGTGGGTCATTGAGGCTTGGCTAG SEQ ID CAAGCGTCACTATGTGTTCAGCCTCACGGGGCGGGGATCACAGGATCACGGGGATCACGA NO: CCAGCGGGAATCACAGCGGCTTGCCAGTGTGTGTGCCAGGTGGCTAGCCCTCGGTAGGGA 2125 CAGCCTCCCTGACTGTGCGTGACAAACCCGAAGAGGTAGCACCATCCCCACTTTGTAATG CCTCCTGGTCAA MAP7D1 ADXCRSS.Hs#S1907164_at GGCTTAATGTGATTTGCTCCATAACACTGTGCCAATGACATTTCATCAGGGTTGGCAAAA SEQ ID TTGTGAAGAAAATATTTGTATTCAGGGTCAATAGTGTGCCGGGTCACAAGAGGAGTTCCA NO: AACTTCTTGTTTGCCTCTTGAGAAGTTTTTCTTGTTGAGCTGCTGGAGTAAACACTCATT 2126 ATTATTTTTATTAACTTCTACCTGTGTGGCTTAGTCCAGGAAGCTGCCCAAACACTATTG AGATGGAGTTGTTTTGCTTCTCTTCAAATGTTTATCTTTT SPTBN1 ADXCRSS.Hs#S1929015_at AAGCCAAAGACGATGTAAGTTTCTAAATGTTATTTCTCTCCACTACTTAGGAGTTTGCAA SEQ ID GTGTTTGTGTGATGATGGGCTTTATTCAGAAAGTTCTTCATGTAAATGATGATCAGTGAT NO: GGTTTCTATCACTGGGCTCCAGTCACCAGCACTAGAAGGTGTTTGGTTCTGTCTCTAGAA 2127 GGCAGTGAATATGATCTCACTGTCCCTTTGCCGTGGCAGGATCCCTTAAAGTCGATGGAA TCTTTGCCTGT PPAP2B ADXCRSS.Hs#S524340_at TGACTGATAGCTGCCGCTTATGGTTACTTAGTAAAAACTCCTGTTGCTAAATGGCTCAAA SEQ ID TGGATGTCTGTGTGTTTATTTTGCCATCTAATACAAAGCATAAATTTTTCTTACTCCAGT NO: AGCTCATCAAACCCTTGAATCTTTCATCATAAGCACATTGAGGCAGGAACTATGCCTGTG 2129 CCATCCTCACACCTTTGCAAGTGGCACTCAATAAATGTTTCTCAAGTATTGTTCAGACTC AGTGAGGGTCACATCCCCAGGAGGAA LAMB1 ADXCRSS.Hs#S2732721_at TTTTTCCAGGGCTCTAATCACTACTCTGTTAAATTCCTCAAACTTGTAATGCCCCAAGGC SEQ ID TTGATTTTTTCCAGATAATGGCTCTATCGTTGCACATACCCTGATTCTGTCAGGATGTGT NO: CATTGGCAAAAGTAGCTTTCTCTGCCAAAGCTTTCTGACCGTTGGCTCCATCTTAGCGTT 2130 GTTAGCAGGAAAGGCCTGCTACCCAGAGTCAGAGTCAATCAGAGAATAGTTCATGTGGTC CTTAGAACTTTACTCCT FLNB ADXCRSS.Hs#S2733261_at GATGTCAAGACCACTACCTTTAGGCACAGAACATTCTACTAAGATTTCCATTTTTGTGTA SEQ ID AGGTTAATTTTAATCCCTAGGATTTCAAAATTCTCTCTTTCAGGATCCTGCTCACCCTAT NO: CTTCACTATTGCATACCTGAAACTTCAAATCACCTCTCTCTATAAAAATTTAAGGGTGGA 2131 GACCACAGTCATTGCTTCAAAGGCATCAAAGTAGAACATATCTAGAAGCTAACTGCATTT CAACCAAAATATTGATGAAAATTTATTACAAACTAGTCTCTCTCCAGA ARID5B ADXCRSS.Hs#S4463141_at CTGTGTTCAGCAGTGGGTTTACATGGGTGAACATGACAGCACCTGCTCTCAGGGAGCTCC SEQ ID CACCCCTATCCTCCATTGATGGAGAAAACAGATGAGACTCCAGACCAAGGAGGAGTTGGT NO: GGCTCCCAAAGAAACAGTGGAGCCCAGGGGATGAATAATTAAAACGTAAAGCACATCCCA 2134 GAGCTCAGCACTTTGAAGGTGTTTATGTCCCAGCTCTGAAAAAGATGTTCTGTATTTCAT CTCTGAGTCTGAGATTCTAAAAGCTATGGTTGGTACA ARID5B ADXCRSS.Hs#S3010218_at ATGACTTCAATGACGAATCCTACTGGCATAACATCTATGGTTTCACCAACTCTTAGCAGT SEQ ID GATCTTTGGTTCCAGATTCATGTGAAAAGCCAAGAACCGCTTTCCACAATTTGTCTTGTC NO: ATGACTCTCCGGCTCCATATTTTAAGAAGCAGTCTACACTAGCCCTTGAATCTAGACTCT 2138 AATTTTTTAAGATACAAAGGAAATCATTAAGCCCCGGAATATTAGTAGAATATACGGCAA TATGGATCAAGTAATCCAAAGTATTAGCAATGGTGCAAGAGGCTGTCA FNDC3B ADXCRSS.Hs#S2978758_at ATGTGAGAGTGCTTTGCAGTTGGAAAGTGCTGTAGGAACCCTGAATTCATCTGAAACTGT SEQ ID AGCTTAGTGTTTAAATGATGTCTGTTATTACTTTTTTGAATAGTCTGGAGTGCTTGTTAA NO: AGAAAAAATTATTCTGTGATATTTGTTGAATGAAGCACAGTGAGGAAGACTTTACTCAGG 2142 GCCCTTGTAATAGCTATAGGGACCACTGCAATAGGGTCTTGCAGTGGGGGAGAGAGAATA GGCTCAATTCTGAATACATCATCATGGGCAAGTGGG GALNT2 ADXCRSS.Hs#S2734613_at AATGTGGCATGGGTTCCAAAGCTCTGTGATTTTCCTATACTGAAAGATTTCTCCCAACCA SEQ ID TGGAGGAGCCTAACAATTCAGTCTTCAGGGTCTCTAACAGCACTGACACACTGGATGTTA NO: ATTACATTGTGATTGGAGCTTCCTTCCCAGACACTCCAGTGTACTACTTTCCTCCTTTAC 2145 AGCCTCTCTTCTAACTGCCAATAAAAGAGTCCTCATGAGCTCAGCTCCAGCACAGATAAG ACTGACAGAAGGTTCCGAGGTTGGCATTTGCAAAATCGCATGAGCAT PHACTR2 ADXCRSS.Hs#S2978384_at ATCTGGGAAGATTCTTAGAACCTATAATATTAAACATTTCTGTAGCAAACATGATTATTT SEQ ID GCTCTAAGTGGAATAAGTAAAGATTTTTAATAGCGTCACGTCACTTCAAGTTATGACACT NO: AAATGCATTTTGGAGCGAAACTTACAAAAAACAATATTTTTAAAACTTTCTGGATTTTAG 2146 ACTTGTGAGTAAAGATTAGATTTTATATAAATCGCATTGTGAGTTAGGGAGTGCTTAATG GACTGGCCTTGGAAGCCAGTCAGTATTTATGGCAAGTCAGTGCGTAT PTPRK ADXCRSS.Hs#S2979568_at TGCTGTGTTAGCAACTGACGTACAATAAAGTTGAATTCACCCGAATATCTAAGTCTTAAA SEQ ID AGATAAATGCAAGTAGCTGGTAGCTGATTTAGGCACCAGTAACAGAAGTGAACACCTAAA NO: AAGTAAATGCTATCACAGGTAGGAACATGTGAGTGACCCTGATTACTTGTCAGTAGGAAA 2148 AGATGTGGAGTGCAGGCATATTCTCTTTCTACTTTGGATCAGCAATCAGATTCACTCACA GATCATCGATTC KDELR3 ADXCRSS.Hs#S3732256_at GGCTTAACCAGCTAGACATTCCTCTAAATACATACGTAACAAAAATTGATGGCAGGAGAT SEQ ID TTTATTGGGATCACTGGATACCTACACTCAACAGGCAGAACTTGGCTAATTCCATTTATA NO: CCACTACTGAGACAGTGAAGACAAATTAAGAATCAGAACAGGAAGCACATAGCATAGGGA 2149 TACCCGTGTCAGCGACATATTTAATATGCCCCTCAGCTTAAGACTCAATACTGAACAGAC CAAAAGGCCACCTCAATTGCCGCTCCCGCCACACTTGCTATTGAAACT SLC20A1 ADXCRSS.Hs#S2981378_at ATGAGAATATCCAGCAAACCAGTCCTAAATGACTGATTACTGAAGATCAGATATAACTAA SEQ ID TGACTTCAGTAGTTGAGGTCAGTATTAATTCCAGCATTTTTAGCATAGACAGGAGAAAGG NO: GAAGGAGATGATCATATTATCAGTGGATCCTGTGAAGACTAAAGAGGAAAGGTCTGTAGT 2151 GATTTAGAATCTGAGCAGGTCTCTTTGGTTGAAAAACTATCTAGGTTAACTCAGCGTACA CTAGCCTGCAGCCTTCTGA OPTN ADXCRSS.Hs#S2984022_at AGAAGAGAGTAACCCGGTATAACTGGGACCAGCTTAAAGGAACTGCTTTCCATAACATTC SEQ ID TCCAACTAATTCTACACTAGTGAACAAGCACAGCTGGTCCTGGGTACCCCAGTGCCTAGC NO: TCCTCCATGCTTCCTATGGAACGTGTGGAGACTCAGTGAGGCTCTGGAGAGGCCAGCTTA 2153 CAATGTACACACCCACGTTCTCCAAACAGTCACTGTGTAGCTTATAACACAACACAAAAA TTCTCGGAA CAPN2 ADXCRSS.Hs#S2984172_at GAGCCACCACGGGTAGCAAAGTGAACTTCCCCCGAATCACGGTTAAGCCCCCTGGGCCAC SEQ ID ATGGAGCTGTCATCTGCAGTTTTTCCCACCTCGGAGGCCTGACCCTGTGCTCTCCATAAT NO: CAATGAGTAGATGTGGCCCTTTATGTTCCCTGAGGCTTCCCTGACTGCTCATTAAAAGGA 2154 TCTGCTCAGTCCTAGTGAATTGATTTACTTTGCCACAGTCCTTGAAGGATGCTACAGATC AAAAGGTGTCCAGGAAAGTGATCTTAAAGATGCTGACACTACTCCCAGTT EGFR ADXCRSS.Hs#S2984803_at CGCATTGCGTGGGCACAGGAATCTCAATAGCTGGCCCCAGAGCAGAAGCAGAGAAGGTGT SEQ ID GAAGGCCTGGACTCTTCTGAGCTTGAGGTCAGGGGATCTACTTGCACATTAGAGTTATTT NO: AAATGAGGAAAATGCATGCCCTTTTTGAATCGATGTTGTCAAGCCTTTCTTTTCCTAGGA 2155 GAATCTTTCGATTCCCAGCATGGGGAAAGCATGTTTTCAGGTATTAAAATGAGTAAGGTT GTAACAGTTACCATGAATCCACATGTTGTGCCCCATTCTAAATCAAGTA RBPMS ADXCRSS.Hs#S2984882_at ATCCTTTGATTGGATCTAGCCTCCAGCTCAATATACCTTCCTCAATTGGCCTACAAGAAG SEQ ID AAAAAGATCTGAAGCTCAGCATAATGCTGGCTTTAGCCAGAAGAATCCAGCCTTTAAGCC NO: ATCTATATGTGTAGCCATGAAGGACCTTCTAATATGCCTTGTGAGCCCTTATGGGGCCAC 2156 CTCACAGCCACAATTTATGCCCACGTGTCAGCCTCACAGACTCAGG COL4A2 ADXCRSS.Hs#S2984630_at TTTTCTCTAAACGAAGGCTTTCTGCACAAAAGGTAAAAGAAATCCAACTGTTTGGCCCAT SEQ ID TTAAAATCAAGTCACTGAAGTTTCTCTGAGCTCAATCACACTCTTCATCTCTGAGGTTCA NO: TCTCTGTTCTTACCACATGATAACGTGAAAAAATAGTTTCTTAAAGAGCTGGCCCCATCA 2159 TCTCCAGAAATGATGTTAGGGAAGGTCCGTGGAAGGCACAGGCCTGCAGTACTGAAGGCA GAGGCATAACTGCCAACCACAATG LPP ADXCRSS.Hs#S2984275_at GTAGCAGAAGCAGGACTGGAACCCAGAACCCAAGTTGGACCACTAGACTGGTGCCTCTCC SEQ ID CTAAGCCCACTCTGCCTCTTCCATGTCTGTGAATGAGCTTACCACTCCTAGCTATGCAAA NO: ACTGCATAGAACCATTTCAGCAAGAGGCTCAGGTAGCATTAAAGAAGTTCCCACCTCAAC 2160 GATGTCAATTTTTTGTTACTGTTGTCTTGAGGAAGCATGTTTGCTTTTAAACGCTCCCAA ATTAAAAGCCATTCTCAGCCTTCCTACAATTGTATG EPHA2 ADXCRSS.Hs#S3000558_at TGAGCAGTGTTTCAGCGCCCAGAGAGACACTGTGGAGAAGGTCCACCAGGATGCCTACCT SEQ ID GCCTTACACAAGAGCCTAACTTTGGCACACCTGTGGCACACCTGTGGAGAGCTGTTCTGG NO: CCCCGGTTGTCTGGCAGGCCTGGGCTACTCCGAGCAGGGTAACTGGGGCACAGAAGCTGC 2169 ACCTCCGGCTATACCCTGGTTTTTCCAGTTCCTGATGCCCGCCCCTCAGGTGGCAGCATG AGGTGACTCAGGGACAGACGCACTTATCGTGACGCAAGTCCACCCTGTCGAGTG FNDC3B ADXCRSS.Hs#S3003052_at TTTCTTCCTACTCCAGGGATCTCCTCCCTTCCCCAGGGTTGAAGCAATGCACACTGAAGT SEQ ID ATTAATAGTAGTGATCAGCACCTTCAAGACAGCAGGACCCTTCTGTTGCCTTCTGGCTGT NO: GGTGTGATGTCCTAGGGCCTGTGGTGCATAAGCAGGTGGAATCTAAGCACTGACCCTGGT 2170 CATTCTACATATAAGAGGAAGAGGACTAGGAAAGCTCGACAAATGCTGTTCTCCTCTTCA TGGCAAAGCCTTGCTCTTTGGAATCCTTATCTGCATTTAAAA MVP ADXCRSS.Hs#S3017763_at GTGAAATAAGCCACTGACCAGTAAACAACTGAGGCTTAAACCAGCATGCCAGCTCAGGTG SEQ ID GGGAGCCCCCAGCACTGGTTATATTCCCTAGATTCCTCACTGGATAGGAAAGTTGGGCCT NO: CAGGCACTCTTCCCTCCTCTGCAGTCAAACAGTGCAGATGAAGAGCCAGGCTCTGTTCCC 2174 AGTGCTTTATGTGCTAACTTGGTTGATAATGTTATCCATTCTCATTTTGTAGATGAGGAA ACAGGCACAGGGTGGTCAAGGGACTTGTTCAAATCACTGATCCCATAAGGG MALT1 ADXCRSS.Hs#S3002450_at GAATTGTGTTTGTTCATCCGTTAAATACTTACTAAGCTCCTGCTCTCTATGCCAGGAACA SEQ ID CACAATTAAATTAATGTTAGACCATCTCTGCCCTTACAGAACTCCTTAGCTTCTTGGAGG NO: TAGTACCATATCAGTCAGGAGCAGAAATCCTAGCTGCTTTCTTTCGTATATATCATAACA 2176 TTTAATTGTATTTTATATTATACTATTGGTTACAAATATTTTTTATATATCAGGATATAC TTCAGACAGCATT GALNT2 ADXCRSS.Hs#S3741276_at GGGAGCCAGACAGTAGACATGAAGTCAGTTATGTCGTGTGCAGAAAGGTGCTGTGTGCTG SEQ ID TGGAAAAAATAGAGCAGTGTATGGGGATTAGGGATGAGGGCGGAAGGATAGTTGCAGTAT NO: TAAAGTGGTGATCACGTAGGCTCATGGGGAAGGCAGGATTGGAGCTGAGACTAAGAGGGA 2179 GCCATTGTGGTTCCCTCTGCTTCAGAGGTAGCCCCTGGTTTCATCTTCGTCCAGCCTCTT TTTCGGTGATCTCTCTACTC AHNAK ADXCRSS.Hs#S3016566_s_at GGGTAGCATCACTGGCCCCAGTGTGGAAGTTCAGGCCCCTGACATTGATGTTCAGGGGCC SEQ ID TGGGAGCAAACTGAATGTGCCCAAGATGAAAGTCCCCAAGTTCTCTGTATCAGGTGCAAA NO: GGGAGAGGAAACTGCGATTGATGTGACACTGCCTACAGGTGAAGTGACTGTTCCTGGGGT 2180 CTCTGGGGATGTCAGCCTGCCTGAGATTGCTACTGGTGGGCTGGAAGGAAAGATGAAGGG TACTAAAGTGAAGACTCCTGAAATGATTATTCAGAAACCTAAAATCTCCATGGG TGFBR2 ADXCRSS.Hs#S3019327_at ACCAGTTTGGAGGACTACGTGCACAGATGAAGCCAAACCTCTGGCCCATCATCTATTCCA SEQ ID CCCTTCACGTCCCTCATGCCCGGGTTCCACTGGAACCCAGCGGCCTCACACATCCTTTTG NO: GCTTACAAATTTCCTAGCTGGTGACCATTCTCCACCACCTCCCCCCAAGTTTTACCATTC 2182 TCTATTGGTGCCCTACAACGGCTCCACCCTTGGAAATAAGGCCGGGTCTAAATGTTACTT TTTCTAGTGGGCCTTCCTGGATTATCCATCCCACGGTGATTCCTTT TIMP1 ADXCRSS.Hs#S2992355_at GAGGGACAGGTGATCACACGGTATTGGACACAGGGAAAGGGAGCAGCCAGAATTTGTAAG SEQ ID GGAGCAGTCTCGGGCTTGGGGAAATAGCAAGAGAGATCAGGGACAGCCCTTAGGGTTGGG NO: GAGCAGCCACAGGGACACAGAATAGCCAGAGGGAGCAAGAAACAAGCCCACGATTTAGGG 2183 AATGGCCCCGGGAAGGATCTCCCGTTGGAGGTCAGGGTCCAGGCACTCACTGTGCATTCC TCACAGCCAACAGTGTAGGTCTTGGTGAAGCCC GALNT2 ADXCRSS.Hs#S2992100_at TTTGAGGCCCACCAGCTGATTCTGAGAACCTCCTGCACCACCATGGAAAAGGGATTCCCT SEQ ID AGCCTTCTACTAACCAAATACCCCAGAAGATACGATTTCAGCTAAAAAAGATAGTGGTTC NO: CATTAACCTTAGGAGCCAGGAGGCGAGACCCTGATCCGGGGCGCTCTCTGCCACCTACCG 2184 CCAGAGCCAACCTCCCTGCCTCCCTCGGAACCCCCAACACCCCAGAACCTCATGACCCTT GCAGAGCCAGCCTGCTGCCTCCTTTGAAGAGAACCATAAGAGAAGCTTCAGG TPM4 ADXCRSS.Hs#S2991999_at GTCGGAATGGAGTGCCACAGATGAACCACAAGAGGAAGAAAAAAACACGTGAGCAAACAA SEQ ID AGCACAGACTAGGAGAAAGCTGTGTTCCATGTGAACCAGATGAAGAAAACCAAAGATCTA NO: TGGAGTTTGATCTCTAAGTGGTTTGAGGTTCTGCAGGGTGGATTAGCCACAATGAAGCTT 2186 CAAAACAGTGGTAACCAGAAGTGACAGAGCTTCCCCCCACTGGTCCCCACCCCTCAGTAA ATTTCGGGATATCCAATGACG PPP4R1 ADXCRSS.Hs#S624701_at CAATGTGTTATGTTTTCAGATGACTTACGTATGTTTTTGTTCATCAGTATTTTAAAAAAT SEQ ID AATCACCTGTTTGTGAAAATAATGGTTTTGAAAACAGCATTATGATGAGAGGGAACTTCG NO: TAATTTCATGAGAATGTAGATGGTGACTGTTTAAGTGGGAGCTCACATAGGCATTAACAT 2188 CACCCTCCTTTTGCACAGTCCTTTTAAGTCTCCTGTTAAACATCTTTTATTGTGTGTATT TAAAGGCACACAGATGCTTTTTCCTGTATTCATCTTACAAATTTACCTACATA SYNJ2 ADXCRSS.Hs#S756942_at GGGCCATTCAATAGTGTATCTTATAAGATAAAAGGTGAGGTGTCAACATTTGGAATTATT SEQ ID TTATTCCTAAATAGCACATGAATTATTTTGTGACTACTTAAAGCAGATTAATAGAGTTGG NO: TTTGCCGAGAGGCAGGGATGAGCTGTTCTTGGTCAATATCAACACTGAAGGCAGGGCAAT 2189 ATTTGTACCCCCTCCTGAAACCAAGTCCTTGAGCTCAAACATTCCAGCTTTTTGCTCATT ACTCATCATCCTAGAACTGGATTTGTAAGAATCATCTCTTTAAGAGTGT PTPRK ADXCRSS.Hs#S794492_at GACCTTATTATTTCTCAGTTTACATACCAATACTCTCCTATACATACACAATATACTAAG SEQ ID AGGAATACTGTTGTCTTCGTACCCAAATTACACATAAACAGATAAAAACTGACTTTTGCC NO: ATCCCTTTGCAAATGTTGTAGCAAATTCTAATGTTCTCAGGCCACGCTGGTTCATGATCC 2190 GAGAATCTGAGACAGTTATAGTCGAAATGTCATAGGAGGCAGGCGTGGTGGCTTGCCCTG TAATTCAGCACTTGGGAGGTCCCTTGGACGA ARID5B ADXCRSS.Hs#S797577_at ACTAGATCTGTTTTTCCTGACCTGAACACCATACACCTGTTGAGTTCACTAAGTACTTTG SEQ ID GGGTTTCCAAAATGATTGAGGAGGTGCTAATTAAAGAATCAACATTTAACGTTTTCAATG NO: ATCCACCACCTATTTGATATTAACCACATCCTTCCACGGGATTGAGTTATAACTAATCCA 2191 GCCTTCAACTGGGGCAGTAAGAAGTGCTGAACCAGCAATACAAAAAGCTAGAGTTCTAAT CTTGGTTTGGTTGCTAACTTGCTAGGTGACCCTCAGTTTCTACC FHL1 ADXCRSS.Hs#S3747393_at TGCAGCTCCCTTTGCCAAGGCATTTCCTATAGAATCCTGCCACCCAAAAGGTACCAAATA SEQ ID TGAGTTTCTATTAGCTTTCAACTTCTTTAAACATATGCTAATTTGTTCCTCTCCCCCGAA NO: AAAGAGATTTGCACGGGTAAATAGATAGCAATTATTTCATTTGTGCAGGAAATACAAGAA 2193 TTGAGACTACTTTCTAAAACTATCCACAAACATGGTTATTGTGCTAGCAAACTTCCAGCG TAATTTAGAGAGAAAGAATGAGAGAAAATAAATGAGCAGTTGCCTGGTACTCAC WDR1 ADXCRSS.Hs#S3747394_at ACTTGGACCTGAGGATGGCCCCAAACTCCCTTGGCTCCTCTACAAAATCAGGGCACTTTT SEQ ID CAGGGAGGACAGCGTCCCACGATGGCCACTTATTTATGTGGTCTGTCCTTTGCAACAGTC NO: TCCGCAACAGCCTTCCATTGAATTCTGTCTCATTGGACACCTTTCTGGGGACTGGGGACA 2194 GGGTAGGCCTGGGCCCGCAGGTTCTCAGCTTGCAGCTGACAGGGCACGGACAATGTGCCA GGCAGGAGCGGAGGCCCTTGCCAACTGATT PHACTR2 ADXCRSS.Hs#S3747744_at AGGGTAACCTCTCTCATGATTCATTACCTCCCACCGGCTCTCTCCCATGACATATGGGGA SEQ ID TTATGGGAACTACAATTCAAGATAAGATTTGGATGGGAATACAGCCAAACCATATCAAAG NO: AGTATATTATGATCCATGCTGATATGAAGGAAAATTATTCTGCCTTGGTATGAGATGGAT 2195 TGTGAAAGAGAAGGACAAGATTTGCTGATTTATTCAAAACATATTTACTGCATGCTTACA ATATACTGGCCCTCTTCTAATCAA PHACTR2 ADXCRSS.Hs#S3747744_x_at AGGGTAACCTCTCTCATGATTCATTACCTCCCACCGGCTCTCTCCCATGACATATGGGGA SEQ ID TTATGGGAACTACAATTCAAGATAAGATTTGGATGGGAATACAGCCAAACCATATCAAAG NO: AGTATATTATGATCCATGCTGATATGAAGGAAAATTATTCTGCCTTGGTATGAGATGGAT 2196 TGTGAAAGAGAAGGACAAGATTTGCTGATTTATTCAAAACATATTTACTGCATGCTTACA ATATACTGGCCCTCTTCTAATCAA LPP ADXCRSS.Hs#S3748577_at ATGGCAGTGAGCATTTATTCCGGGCTGAGTTTTACACTACCCATACTGTCTCTAACTCTC SEQ ID CCAACACTCCCACAAGGCAGGTGCTATTATCCCCATTTTACTTTTGAGAAAATTAAGGCC NO: TAAAGAAGTGAGAAAGCTTGTCCAAACCGCTATAGCTCTTGGGCAAAGGCATTAGTGACC 2197 AATGTGTATTTGACTCCAAAGCCCAGGATGTTAGCCACAGTGCAGGGCTACTATCCTTTT ATACAATCTGTCAGGCTTCTTCCATCCGTGGCATGTATTCATCTA ZCCHC14 ADXCRSS.Hs#S3747057_at GGGTTTACTAGGCTACAATCTCTACTCCTGAACTGGAAAATGTTCACAATAAATAGGTCA SEQ ID GGAAAAAAAGGAATGATTTCACTGGTTAATGTGTACTCATAGGCACTGCCCACACAACGG NO: TGTGTTTTCCACTTTCAGTACAGTCCCACCTTTCTTTTCCTCTGCTATTTTCTTCAGCCA 2198 GCCACAGGGTTAAGAGCATTAGCTCTGGCTTTGAATCCCAGCTGACCTCAGGAAAATTTC TTATCTGTGACTCAGTTCTCCCATCTGAGTGAGCTC LAMB3 ADXCRSS.Hs#S3745344_at GTGAGTAATGCGGTGGCCCCAAGGTGGTGCTGAAATATCCTTCCTCAACAAAGAAGATAA SEQ ID GCAGCAAATGTTTTGAGGGTGGCCACAGGGGTCATTACTGGTGGGAATTCAGGAAAGTCA NO: GCAAGGGGAGCTGGCGAGGGTGTTTCCGTCCCTTCTCAAGAGTCCGTGTGGCTGTGTGAA 2202 CAGTGGGACATCAGGGATTTCTCCCCAGGCCTACTTTTCAGGATTCCCTCTACCTA ACTN1 ADXCRSS.Hs#S3748482_at GGCACAGAGGAAACCCGCTGAGCCTGCTTCCTTAGTTCTGGCAGATGGGTCAGCCCCCAC SEQ ID AGGACTCAGGATTCAATTTAGCCCGGGGTTCTGGCTCCATCTCCCACAGTGCCGGTGCCA NO: GTGTGCTCCTAAGTACTGTTTGTGCAAACCTGGCTCTGACTGAGACAAGGAGCCTTAGGA 2203 GTAGTAGGGACAGGAGACACAGCAAACTAGGGCTCAGA FNDC3B ADXCRSS.Hs#S3748224_at GATTGCCTAGGAGGACACTGTCCTCAGTCTTTGGGGCTAGAAGGTTGAAGAGAAGTAAAC SEQ ID TTTGACTGAATTATCCTTCTCATAGAGTTTAACAGGCACAGTGGAAATTCCTAGGCCGAT NO: TTCACTCTCATATAACACTGTTGGCAGGAGAATGGGTAGCATGGGAGAGTATCAGCGATA 2204 CCAGAATCTGACCAGAAGGACAATGTACAAGAAAAGGTAGGGACTTTCTGAAGGCATTTT TGGTGGCCGTTGGTGGGGATTAGGTATACAGCACAGATTAGACTG FLNB ADXCRSS.Hs#S3748946_at ATTCTTTGTCAGGAGAGTTTTGTGAATTTCTGTTTAGTGGCAAGTTGTAGAAACCACTTG SEQ ID AAACTGCTTAAAGGCAAAAGAGGGAGCCACTTGTCCCAGTAACTGAGACATCCCAGAGCC NO: GACTGCCCCCAAGCATTACTTGGTCCCAAGTTTCAAACGGGTCTTCAGGGTTTGATCTCT 2205 CTCCTCATCTCCAGTCTGCTTCATTCATTTTGGCTCTATGTGGTGGCAGAAGGGCTTCTG GCATCTCTGGACCTTTATGCCTCCCAGGT COL4A1 ADXCRSS.Hs#S3748447_at AAGGATTTAAACCAACCTGTGCAATGCGAGTGTGTTCAGATACCTGGAGCCAGCCTTTGG SEQ ID AACCTGCTGGATCAAAACCAACGTGTGCTCTGTGGGGCCCCTGAAACACGAATCCTCTGT NO: GGGGTTGATTGAGAAAGGATTCACAGGCTTCAAGTCCCAGCAAGATTTATTTGCTAGAAT 2206 TCAAGCAAATCTTTACGAAAGGGAGTTCTCATGGATGAGGCCACTGTTGGGGGCTGGGCC AGGACTAGATGGAGCCATGGATTCCA NT5E ADXCRSS.Hs#S3735513_at TTCCCTCTGGCAAGGAAAGACTCAGATAAAATTCCCCATGACTTCTAAAGGTGCTCCTGG SEQ ID GCATTACTTTTCATTGTTTTTCCTGGGGATGCTGTTTCCTCAGAATGTCGTTGTATTATA NO: GTACATTCCTTAAGGGATATGGTTTTCATTTTCCTGAATGTTGCTCCTTTCTCTCATTTT 2207 ACCAGCAACTTGTTACTCCCTTTCACTTTCAGACTCTTTTCTCTCTTTCCCTTCTCCTTC AGCAACTTCTCTCCCCATTGAAGTTAGAAGT ZCCHC14 ADXCRSS.Hs#S3734556_at GCTTTAGCTGCCAAGTTTCTGTTACTTGTATTTTTTAAAAACATGCTACTCCGATAGGTA SEQ ID TTTCTGTTACTTCTAAGTCACAGAATGACACTGATAAATCATACATCAAAATAGACTATT NO: AAATCTTTAATGTTCAAATACAATTTTTCTAGAAAAGTAAAACGCAGAAGGCTGGAAGGT 2208 GTGACCGGCACTCCACTCTGGCCTTGCTCCTTAACTGCAAAGTCACACCTGCTGACTGGG CGCTTACCCTACCCCGACACCAGGAGGATGCCAGTCTACGCCTCGAAA FTH1 ADXCRSS.Hs#S3729871_at TCCCTTTTCTGGATTCTCAAGCAGTTACTTTCACGGTCAGAACACGCAGCTATTATGATT SEQ ID GAAAACTTAAAAGGGCAACAATTTCAGTCTTGCTTCTAGGGCTAGACAGGAACTTGGCAA NO: ACATCTGTGGCCTGTTCAGCAAAGGATGTTAATATTTAAGAATCTTGTCTTGGGCTGGGT 2211 GT FTH1 ADXCRSS.Hs#S3729871_s_at TCAGATATTTCCCTTTATTCCAGATTTCCTGGACACTTTCACCCAATTATAAACACCCCA SEQ ID CTTCAGCCCCAATCACGTGGGAGGAAGTGTAACTTCCCTTTTCTGGATTCTCAAGCAGTT NO: ACTTTCACGGTCAGAAC 2212 FTH1 ADXCRSS.Hs#S3729871_x_at ATTTCCCTTTATTCCAGATTTCCTGGACACTTTCACCCAATTATAAACACCCCACTTCAG SEQ ID CCCCAATCACGTGGGAGGAAGTGTAACTTCCCTTTTCTGGATTCTCAAGCAGTTACTTTC NO: ACGGTCAGAACACGCAGCTATTATGATTGAAAACTTAAAAGGGCAACAATTTCAGTCTTG 2213 CTTCTAGGGCTAGACAGGAACTTGGCAAACATCTGTGGCCTGTTCAGCAAAGGATGTTAA TATTTAAGAATCTTGTCTTGGGCTGGGTGT COL4A2 ADXCRSS.Hs#S3736483_at CTTCCAGGCTGTTAGGAGTCTCACAGGCTCATCCGAAAACCAATTCATGCTCCTGAGCTT SEQ ID CATGGGTTCGCCTGCCAGTGGAGGCCTAGCCTCCATCTCGCTTAGGATGCCTGATGTGGG NO: CTGATGGCAGAATCAGGGGAGCGACACCTGCTTCCCACACCACAGAGAAGCCTCTTCGGG 2214 CTGGGGTTGGCAGCAGGGACTAACGACAATGCCATAAACAGATAAACAGTGAATGCACCG AGTCACAGTTTTAACCCGCATTCT PHACTR2 ADXCRSS.Hs#S3740773_at ACACACACAGATCCCAACAAGAATGGACACTGATGGGTGAGGACAGCTGCTCCCTGAGGA SEQ ID GATGGCCACTGGGCACTGTTGGCACATCATTCTGGGAAATTTCAGTTTAGAGCTTATTAG NO: AAGAGACCCAGACACTAAAGGTCAAAGGCGGGACATGAGGAGCACAGGGAGAGGGATGTC 2215 TATTGGCATTCAGAGATCTGTTATACTGTCAACTAAACCGCTCTCTGAATTTGAGCATTA TGGTCATACAT MVP ADXCRSS.Hs#S4460147_at TTCACTTTCCATAGTGGGAGTCTCGGGTTTGAAGTAAGGAGATTAAACAAACGGTCCCAC SEQ ID CCTCAGTACCACTCATCGATCG NO: 2218 EGFR ADXCRSS.Hs#S3896483_at TCAAGGAAAACTCTACGTCCAAGTAAACTCAAGATATCAGGAAATAAGATTAAAAAGGAG SEQ ID TGTGGGGCTGCCACTGACATTTTAAAATCTCCTCTTTGTATTCTCTATTTTCAGAAAACA NO: ATTTCAACATCAAGCATGAAGTTTATGATGAATATAGGAAATAGAAAGGATGGTGAGGAT 2220 TGAGGATTTGTCTGTGGGAAATTATTATTGTTCTGATATTTTAAAACAGAAGAGCCAAAC CAAAACAACTGTTCTTTTGACTAAAAAGGTGATGAGAGATTTTTAGTGTCCCCA CD44 ADXCRSS.Hs#S3898008_at GTGAAACCAAAAGAACGCAGGCAAGAAACAGAACAGGAGGGGGAGGGCGACTAAAACATA SEQ ID CACTACCAGGGGAAGAAGAAAAAGTGGCCGCAGCCCCAGGAGGAAAATAAAGAAAAGGAA NO: CCCACCACCTAGAAGACAGACATAATAAAAAAGAACACGCCGAGCATGCACGCGTCAAAA 2222 ACAAAAGAAGAAGGAGAAAACAAGCACCGCACGAGGTGAAGTCATTTGTGAAGGAAACGC ACAACACAATATGTGCGGGGAGGAAAAATAAGAGCGATACCACCCTCACG COL5A2 ADXCRSS.Hs#S821070_at TCCTTTGGGTCCTGAAGAACCTACAGGACCCCGTTCTCCTTGAGCACCTTTGGGCCAGGT SEQ ID AAACCATCAGAGCCTGGAAAACCACGATTGGCAAGAGCACCCTTTCTTCCAATGGCCCTG NO: GAAGAACAACTGTTCCTGAGGTCACTCTGGGAACCCTTTTGCCTTCTTTAGCGGGTGGGC 2223 CTATCGGACCTGGATACATGTGGCCTGGTTC NR3C1 ADXCRSS.Hs#S821188_at AATGAGCAAGCGTAGTTCACTAAATATAAAGGAGTTTGTTAAAACCAGACAGTAATAGCT SEQ ID ATAAAAGGCACAACTTCCCTTTTCTGATATACACTTGTAAACTTTTTTTCAGGTTTCCAT NO: GCATAAATCAAAAATGCTATCCTAACTATACAGGGGGGGGATACACCAACAGAAAGTCTA 2224 GAAAATTTCATCCAGCCAACTGTGTAAAAAAGTATGAAGAGAAAGTTCCTCACACAGACT TTGGGCACTGGTGGTTTAGGTGGCATCCATCTTTGACTGT TGFBR2 ADXCRSS.Hs#S849165_at GGGCATTTCTTAATTGCTCCTCAGTTCTAAGTGTCCCTCAGAATGCCTCAGATATTTGCT SEQ ID TTGACTCAGCAGAAGAAGGGAAGATCGTGGCCAGAGATAGCCTGAACCCTGCGAGAGGAG NO: GTTAGAAAGCAGAAAGCCCTCTGCCAGCCAGGTGGGTACCAATGGTCGTTCCTAGGATGA 2225 GACCTCATGTAACAGAGCCCAGGCAGTCCTGGGGAACTGGACATAGCTGGTGATTGGCAA CAAGTTGATGGCCTGAGACCTTTGACACT CAPN2 ADXCRIH.1382.C1_at GTATCTGGACCTCAAAATTATGGGAACATTTACTTAAACGGATGATCATAGCTGAAAATA SEQ ID ATGATACTGTCAATTTGAGATAGCAGACGTTTCACACATCAAGTAAAAGATTTGCATATC NO: ATTATACTAAATGCAAATGAGTCGCTTAACCCTTGACCAGGTCAAAGAAAAGCTTT 2233 CAPN2 ADXCRIH.1382.C2_s_at TGGCTCTGTTTCTCAGTACTTTGAAGTTATAACTAATCTGCCTGAAGACTTCTCATGATG SEQ ID GAAAATCAGCCAAGGACTAAGCTTCCATAGAAATACACTTTGT NO: 2234 CD44 ADXCRIH.1441.C1_at CATCAAGAACAGACAAGGGTGTGTAGCGGTTTACAAATACAGCCATAAAAAAGTCAAACA SEQ ID GGATCTACATGGCATCATCATTCCCCTTGGCCAATCCT NO: 2235 CD44 ADXCRIH.1441.C1_s_at AATCGGACACCCTGACTGATGAATAAATGCCACAAAGGACTTGCCAAGTGGGAGAAAATA SEQ ID TGAGGTTAGAGGATAAAGCCAGTACTCTCTTGTTTGGTCATAAACTTGCCTATCTGGTGA NO: TAAGATTCCAATGATGGGAATCCCTTTAACCTTTTGAGGGACTCCCCAGGCACTTAACTC 2236 ATCCTAAATAGCAACTGCATCAAGAACAGACAAGGGTGTGTAGCGGTTTACAAATACAGC CATAAAAAAGTCAAACAGGATCTACATGGCATCA CD44 ADXCRIH.1441.C2_s_at ATGGTCCATTCACCTTTATGTTATAGATATGTCTTTGTGTAAATCATTTGTTTTGAGTTT SEQ ID TCAAAGAATAGCCCATTGTTCATTCTTGTGCTGTACAATGACCACTGTTATTGTTACTTT NO: GACTTTTCAGAGCACACCCTTCCTCTGGTTTTTGTATATTTATTGATGGATCAATAATAA 2237 TGAGGAAAGCATGATATGTATATTGCTGAGTTGAAA IL8 ADXCRIH.1699.C2_at TAAGAGCTCCACAAGTCTGCTTGTACGTAGTTATGTAGATTTACCTGAATATTTATCAAT SEQ ID TCATTTGTTTTCCATTCTTTCTCATGTTATGTCTCAGGCCTTTTATACCAGTTTCTTTCT NO: GCCACAAAGACATCCTTAGAATTTAGTTTAGTGATGGTCTGGTGAAGACAAATTTTCTCA 2238 TTGGTTGTCCAAAGGAAGATTAATTCCAAGTTTGTTCTTGAGAGGTATTTTTGCTGGCAT ATGTTCAATTTGTCATAATATTTGTCAATTGTAAACTGTTGTGCAC CD63 ADXCRIH.1914.C1_s_at TAATGTTACTGTGGGCTGTGGGATTAATTTCAACGAGAAGGCGATCCATAAGGAGGGCTG SEQ ID TGTGGAGAAGATTGGGGGCTGGCTGAGGAAAAATGTGCTGGTGGTAGCTGCAGCAGCCCT NO: TGGAATTGCTTTTGTCGAGGTTTTGGGAATTGTCTTTGCCTGCTGCCTCGTGAAGAGTAT 2239 CAGAAGTGGCTACGAGGTGATGTAGGGGTCTGGTCTCCTCAGCCTCCTCATCTGGGGGAG TGGAATAGTATCCTCCAGGTTTTTC FHL2 ADXCRIH.1926.C1_at TTGTGATAGTTCAGTCCCAGGGAAAGAGAAAACTCGCCCTAGGCCCTAGGTGGGAAGATG SEQ ID GTTTGAAATTTTTGTAATCGAGTAAGGCACACCCAAATGTAAAAATCCTTTTGAATGATG NO: CCTTTATAAATCTTTCTCTCACTGTCTATTTAAGTGCAATTAACATATGTCACGAACTTG 2240 AAAGTTTTCTAAACTCAATAAGGTAATGACCAGTTGTTATTTACAGCTCTGTAACCTCCC GTTGCGTCAAGTCTAAACCAAGATTATGTGAC FHL2 ADXCRIH.1926.C1_s_at CGCCCTAGGCCCTAGGTGGGAAGATGGTTTGAAATTTTTGTAATCGAGTAAGGCACACCC SEQ ID AAATGTAAAAATCCTTTTGAATGATGCCTTTATAAATCTTTCTCTCACTGTCTATTTAAG NO: TGCAATTAACATATGTCACGAACTTGAAAGTTTTCTAAACTCAATAAGGTAATGACCAGT 2241 TGTTATTTACAGCTCTGTAACCTCCCGTTGCGTCAAGTCTAAACCAAGATTATGTGACTT GCAATAAAGTTATTCAGA FHL2 ADXCRIH.1926.C2_at CGCTTCACAGCTCGCGATGACTTTGCCTACTGCCTGAACTGCTTCTGTGACTTGTATGCC SEQ ID AAGAAGTGTGCTGGGTGCACCAACCCCATCAGCGGACTTGGTGGCACAAAATACATCTCC NO: TTTGAGGAACGGCAGTGGGCATAACGACTGCTTTAACTGTAAGAAGTGCTCCCTCTCACT 2242 GGTGGGGCGTGGCTTCCTCACAGAGAGGGACGACATCCTTGTGCCCCGACTGTGGGAAAG ACATCTGAATCAACACAGAGAAGTTGCTGCTTGTGATCTCCCACACGAATTTTTATGTT FHL2 ADXCRIH.1926.C2_s_at TCAGCGGACTTGGTGGCACAAAATACATCTCCTTTGAGGAACGGCAGTGGGCATAACGAC SEQ ID TGCTTTAACTGTAAGAAGTGCTCCCTCTCACTGGTGGGGCGTGGCTTCCTCACAGAGAGG NO: GACGACATCCTTGTGCCCCGACTGTGGGAAAGACATCTGAA 2243 MYL9 ADXCRIH.2136.C2_at TAGTCGTCTTTATCCTTGGCGCCATGTTTGAGGATGCGGGTGAACTCCACGTATTTGAAG SEQ ID TTGCCTTTCTTATCATGGGTGCCTCCCGGTACATCTCGTCCACTTCCTCATCTGTGAAGC NO: GGTCACCCATGGTGGTGAGCAGCTCCCGGAGGTGGTCCTCATGGGATGAAACCTGAGGCT 2251 TTCCTCGTCGAAGCAGGCAAGGGCGTTGCGAATCACATCCTCGGGGGTGCGTGCCGTTCA GCTTCTTCC ACTN4 ADXCRIH.2359.C1_s_at TTGGGGAGACTTGGGGCCAGCGCTTCTGGTCTGGTAAATATGTATGATGTGTTGTGCTTT SEQ ID TTTAACCAAGGAGGGGCCAGTGGATTCCCACAGCACAACCGGTCCCTTCCATGCCCTGGG NO: ATGCCTCACCACACCCAGGTCTCTTCCTTTGCTCTGAGGTCTCTTCAAGGCCTCCCCAAT 2256 CCAGGCCAAAGCCCCATGTGCCTTGTCCA ACTN4 ADXCRIH.2359.C2_at TCAGAGCAAAGGAAGAGACCTGGGTGTGGTGAGGCATCCCAGGGCATGGAAGGGACCGGT SEQ ID TGTGCTGTGGGAATCCACTGGCCCCTCCTTGGTTAAAAAAGCACAACACATCATACATAT NO: TTACCAGACCCGAAGCGCTGGCCCCAAGTC 2257 ACTN4 ADXCRIH.2359.C2_x_at AGGCCTTGAAGGGACCTCAGAGCAAAGGAAGAGACCTGGGTGTGGTGAGGCATCCCAGGG SEQ ID CATGGAAGGGACCGGTTGTGCTGTGGGAATCCACTGGCCCCTCCTTGGTTAAAAAAGCAC NO: AACACATCATACATATTTACCAGACCCGAAGCGCTGG 2258 ID1 ADXCRIH.2765.C1_at GCACTGGCGAGGAGAGGGCGCTCCTCTCTGCACACCTACTAGTCACCAGAGACTTTAGGG SEQ ID GGTGGGATTCCACTCTTGTGTTTCTATTTTTTGAAAAACAGACATTTTAAAAAATGGTCA NO: CGTTTGGTGCTTCTCAGATTTCTGAGGAAATTGCTTTGTATTGTATATTACATGATCACC 2261 GACTGAAAATATTGTTTT RBPMS ADXCRPD.1301.C1_at TGAGGCAAAGCCCAACACACCTGTCTTTTGTCCACTTCTCCAGCAAATTAGATTTGTCTC SEQ ID TGGGAATGTGTTTGTAACATACCAACCTACTGCAGACCAGCAGAGGGAGCTCCCATGTTG NO: AATTTGTTTGTTAGCTATTTTCCCCCCTTTCACAAAAACTATTTCTTGACGACCTTTGAG 2269 AGATTTCAATAA RBPMS ADXCRPD.1301.C2_at AGGCTACTTCTCAGGGCTGGAAGTCCCGTCAGTTCTGCTGAATACTATGTCCCAGGTGTG SEQ ID TGATGGCGGCTGCAATCTGTCTTGTGGGTATTAATGCAATCTTCAGTGGTGGCTACTGTT NO: CTCTAGCTTGTTCTACAAAACT 2270 NPC2 ADXCRPD.1525.C1_at AAAAATTCTTGTCCCCGCCGCTATGTGGAACACCCACTCCCCACAACACCTAGTGTACTG SEQ ID CTCAACAAACACTTGATTTTCGCCCATGCGGGCAACTCTTANNNNNNNNNNNNNNNNNNN NO: NNNGGCGAGATAAATATACTTTCCCGCCGCGGGAGGAAAAACACGCGCCGGNGAAAAAAA 2271 TTAATTTCTTTAATTATTCGCCACCCCATTTATAACACACAAGAGCGGGGGGGACCACAC CCCCCCGCCGGGTGTTGTGGGCGCACACAAAAGAATATATT LMNA ADXCRAD_CD620845_s_at CACGCCTACCGCAAGCTCTTGGAGGGCGAGGAGGAGAGGCTACGCCTGTCCCCCAGCCCT SEQ ID ACCTCGCAGCGCAGCCGTGGCCGTGCTTCCTCTCACTCATCCCAGACACAGGGTGGGGGG NO: CAGCGTCACCAAAAAGCGCAAACTGGAGTCCACTGAGAGCCGCAGCAGCTTCTCACAGCA 2272 CGCACGCACTAGCGGGCGCGT ZCCHC14 ADXCRPD.3467.C1_s_at CCTTCACAGCTTCTATTGGACATATTTTCTTTTTAGGAATGAAGGAAAATTCTCCCATTT SEQ ID TTGAGCCATTCTTTTGTCAATTCTACAAAATTGCATGTAACTTTATAAATATTTTTAAAA NO: GATATAGTTTTGTAAATATTTAATATTCCGCTAATTTGATTTTGAATTGTAAATGTCAAG 2278 TATTCTGTTTTTGGGGTTTTTATGTTTTATTATACTTTGTTAAAAAGGACAAATTGTACA TTTTTAGAATG SPTBN1 ADXCRPD.5087.C1_at GGTTTCCATCCACGATGTCATGGGACCCCATGTTCTCAAGATGGACTCTCTGCTCCTTCA SEQ ID GGAACTGAAGGGCCTTGTCCACATTCTCTAAGCAGTGGATGCGCATTCGTCCCTTGGTGG NO: GTTTAGGCAGCCTCTCTCCAGAGAGGACCTCCAGCAGCTTGATGAGCATCCGTCCATCTC 2283 GAAGGTCAGTGTACAGGTCTGTGATCCGGCAGGACACACGGGCAAGGTGGGAATTGACCC ACTTGGTGAAGGTCTTCTTCTGCACGGC ATP2B4 ADXCRPD.5728.C2_at ATGGGAGCTCATCTCCTTCCATCTCTCCTAATCAAGAGCAAAGGGAACAGCAGGCCTAAC SEQ ID AGCAGGGTTGGGAAGGCAAA NO: 2284 ATP2B4 ADXCRPD.5728.C2_x_at CAATAGTCAATCTTTGGTTTTTCTTTTTGGTACAAAAATACCAGTGCTTGTTATACTAGT SEQ ID TACTAAAAGAAGAAGAAACTCAAAATTCCTATCTGCGTGCTAATTTGAAAAGAACAACGT NO: AGATAGATTTGTTGGCACATATATATGGCATATTCACATATGGCATATATACATATGGGG 2285 AGAAAACATGAACCAAAGGCCAATTCAGTTATGGGAGCTCATCTCCTTCCATCTCTCCTA ATCAAGAGCAAAGGGAACAGCAGGCCTAACAGCAGGGTTGGGAAGGCAAA MAPK1 ADXCRPD.6501.C1_s_at CTTTATTCACAATCTTAGGTCTCAAATATTCTGTCAAACCCTAACAAAGAAGCCCCGACA SEQ ID TCTCAGGTTGGATTCCCTGGTTCTCTCTAAAGAGGGCCTGCCCTTGTGCCCCAGAGGTGC NO: TGCTGGGCACAGCCAAGAGTTGGGAAGGGCCGCCCCACAGTACGCAGTCCTCACCACCCA 2286 GCCCAGGGTGCTCACACTCACCACTCCTGTGGCTGAGGAAGGATAGCTGGCTCATCCTCG GAAAACAGACCCACATCTCTATTCTTGCCCTGAAATACG TMBIM1 ADXCRPD.6583.C1_at CCTCGCCTAATTTTCACCACAAAGATTTTCTTCCACCCCGTTCTCTCCTCTTCCTGTCGG SEQ ID TTTTACGGCCTCTCACGGCGTGGCCATGCCGCTCACTATCACGGACACCCATAAGCCCCT NO: CACATATATTCTTCCCCCCAAAACACTCACTGAGAGTTTTGTTCCCCCCTATATCAGACC 2287 CCCATATATCGCGGTTCTGCCGCCGCCTTTATTGCACGCTGG ZYX ADXCRPD.7105.C1_s_at TGACCCAGGACCCAACATGGTCTAGGGATGCAGGATCCCCGCCCTGGGGTCTGGTCCTCG SEQ ID CCCATCCTGCAGGGATTGCCCACCGTCTTCCAGACACCCCACCTGAGGGGGGCACCAGGT NO: TTAGTGCTGCTGCTTTCACTGCTGCACCCGCGCCCTCGGCCGGCCCCCCGAGCAGCCTTT 2288 GTACTCTGCTTGCGGAGGGCTGGG COL6A2 ADXCRPD.9074.C1_at ACAGCGCCCGCAAGTTGAGGTCATCGTCCCGAGGGTCGTGGCGCCCGTCCGTGATGACTA SEQ ID CCGCAAACACACGTGTCTTCTGGCGCCGGCTCTCCTTGATGAGGCGGTCGTAGGCAAACT NO: TGAGGGCTGAGGGTGTCCAGGTGCCACCTGCAATCCACTCGAGGTTCTCGACAGCCTCCA 2292 TTGAAGCTCGACAGGGAGTCGATATGTTCGTCGTCCAGCTGGATGCACTCAAAGGTGCCC TCGTGCTGTACT LAMB1 ADXCRPD.10237.C1_at GAGAATCCAGTTCTTTGGCTGTGCTGTTGCTTTGGGAAGTTGTGTCAGATAATTTCACTT SEQ ID CTACTTGAGCCATCATTTCTGTAACATCTTTAATCAGTTTCTCTGCTTCCTCAAAGAGAT NO: TCCCTATGTTTTTCAGTGGCTCTGCTGCGGGGCTCTGCGCCAGGATGTCTTTTATCTCGC 2296 TGACTTTCCTCTCCACCGAGTCCACAGTCTCACGGTAAGGCCCGATCACACCACTGATCT TCAGGCCTTGCTTTCTCCAGGAATCTGTGTGTCCTGTTGGCAGCA ZDHHC7 ADXCRPD.11267.C1_at GCCAGTGTTGTTTAGGCAGTGTAACATTTACCGGCTGTGTACAGCAAACAAGCTATTTTT SEQ ID TAGAAACCGACGTTTCAGGGAAGAGGGGAGAGAGCCGCGGGGTCCTGCCCGTGGTTACTA NO: TGAATGTATTGCTGTTGGAGGACATCTCGATCCAAAGAACAGCCGTTCCTGTGCGGCCCT 2299 TCGTTGCCCTAAAGCTTTCATTTTTTAAAGAAATAAAGAGTGCTTGAGGGCCTTGGAACT ZDHHC7 ADXCRPD.11267.C2_at TGGGCTGGCGCCTAGTAGGATTCTTGCTCTGAGCCAATACATTACTGCCACTCGGGGTTA SEQ ID TTCACGGACCACGTTATAACCACACTTCCTCTTAGTCCGCACGAATGCCAGTGATTTTTC NO: ACCTCCGCATAACTGTAATCCTGTTGATCTTCCTGTGCCTTGAGGGTCTTCTGTTTTTCA 2300 CTTTCACTGCAGTTATGTTTGGCACCCAAATCCACTCCATATGCAACGACGAGACGGTAA GCTTTGTTCTCGGCTGTGTGGACTTCA ZDHHC7 ADXCRPD.11267.C3_x_at GGGAACCGAGTCTGTGCAAAGCCTCCTGCTTGTGAGTGTGGGGTAGGCACATGGGGGAGG SEQ ID GTCAGCCTGGCTGGGAGTCCTCAGCAGTTTGCTCCTCTTTGCTGACAAGCGCACTTGCCC NO: CTTCCTCCTCTGCGCTCAGACTCTACAGCTACTCAGCAGTCCAGCTTCTGCTCCCACCCC 2301 GCTCCTGCTCCTGCGGAAAAGGCCCCAGAAGCCTGGAGAGCTGGAGGCGGCCAGGAAGTC AGGGTAGAAGGTGTGTGCAGGGCGTGCTCCTGCCTGGTGACAGAAGTC TGFBR2 ADXCRPD.12527.C2_at TGGCAGGAGCCTGATGCCGGTCAACTTGAAATATGACTAGCAACAAGTCAGGATTGCTGG SEQ ID TGTTATATTCTCTAAAGCCTGGGGTCTTCATCACATGAGCAGATTCCCAGCCAGTGTTTT NO: GACAAGTGCTCCTTTGCAATCGATTGTTTGAACCTATATGTCTGATTTTACATCTACCTT 2306 CTGAGAA JAK1 ADXCRAD_CN418378_at TCCACAGATTATCAAGTCCTTCTCCTGCAACAAATGCCCAAGTCATTTTTTAAAAATTTC SEQ ID TAATGAAAGAAGTTTGTGTTCTG NO: 2311 JAK1 ADXCRAD_AL555086_s_at ACAACAAGACCATTTGTGACAGCAGCGTGTCCACGCATGACCTGAAGGTGAAATACTTGG SEQ ID CTACCTTGGAAACTTTGACAAAACATTACGGTGCTGAAATATTTGAGACTTCCATGTTAC NO: TGATTTCATCAGAAAATGAGATGAATTGGTTTCATTCGAATGACGGTGGAAACGTTCTCT 2312 ACTACGAATGATGGTGACTGGGAATCTTGGAATCCAGTGGAGGCATAAACCAAATGTTGT T NT5E ADXCRAD_BX404438_s_at TTGTGGGAATCGTTGGATACACTTCCAAAGAAACCCCTTTTCTCTCAAATCCAGGGACAA SEQ ID ATTTAKTGTTTGAAGATGAAATCACTGCATTACAACCTGAAGTAGATAAGTTAAAAACTC NO: TAAATGTGAACAAAATTATTGCACTGGGACATTCGGGTTTTGAAATGGATAAACTCATCG 2316 CTCAGAAAGTGAGGGGTGTGGACGTCGTGGTGGGAGGACACTCCAACACATTTCTTT ULK2 ADXCRAD_BP319713_at GAGCTTTTCCATTTGGTGCTCCAATGTCTCCTGCTGGACCCATCTGCCTAGTGGAAGGCA SEQ ID GCAAAATTTCAAGAAACAGGTGAGGTTGAGCAGCTTGGTGCAACCCCATGGG NO: 2317 ULK2 ADXCRAD_BP319713_x_at AGAGAAGACTGTCGGCGCTCTGCCATAGCACCGCAACCGTGTGAGCAGCAGGCTCATCCC SEQ ID GTGGACCGGTGGTGGGAACGTGAGGAAGAGGGGAAGGAAGGAAGAGCTTTTCCATTTGGT NO: GCTCCAATGTCTCCTGCTGGACCCATCTGCCTAGTGGAAGGCAGCAAAATTTCAAGAAAC 2318 AGGTGAGGTTGAGCAGCTTGGTGCAACCCCATGGGGCCCTGGAGTTGGAGCTCAACAGCA ATGGATTTCAGA RBPMS ADXCRAD_CD172092_at AGCTTTCCAGAAAACCTCCTTCTGACTTAAAACTCTTTTAGGTTGGACAGAAATTCCTGT SEQ ID CCTTGATAAAGAACCACCTAGAAGCAGCCCCCAGCGAGGGGTTCTTGAAAAGTCA NO: 2325 RBPMS ADXCRAD_CD172092_x_at AGGTTTCATTTGTCTTTCTGCATGTGTAATTCAGCCTTTAAATTTTAAATTTTTAAAAAT SEQ ID TATTANGCTGGACAGGCAGAGTTTTCGTTTGCCTGTTTTGCTCANTGTTTGTTTACAAGG NO: CTGGGTGAAATAAACAGCTTTCCAGAAAACCTCCTTCTGACTTAAAACTCTTTTAGGTTG 2326 GACAGAAATTCCTGTCCTTGATAAAGAACCACCTAGAAGCAGCCCC CD44 ADXCRAD_CV026388_at AATGCCTTTGATGGACCAATTACCATAACTATTGTTAACCGTGATGGCACCCGCTATGTC SEQ ID CAGAAAGGAGAATACAGAACGAATCCTGAAGACATCT NO: 2327 CD44 ADXCRAD_CV026388_x_at GTATGACACATATTGCTTCAATGCTTCAGCTCCACCTGAAGAAGATTGTACATCAGTCAC SEQ ID AGACCTGCCCAATGCCTTTGATGGACCAATTACCATAACTATTGTTAACCGTGATGGCAC NO: CCGCTATGTCCAGAAAGGAGAATACAGAACGAATCCTGAAGACATCTACCCCAGC 2328 PTRF ADXCRAD_AL545542_at GCTCCTTCCCTAGGAGCATGGGTGGCACGTGCC SEQ ID NO: 2330 PTRF ADXCRAD_AL545542_x_at AGGGTGCCGGCCCTGCCACCAAGTTGAGAGCTGGAGGGGAGGTGGGGAGAGAACATCACA SEQ ID GAGCAGCCAGCCCTGGTTCACTCCTGGSAGTTTCTTCTCAAGCTCCTTCCCTAGGAGCAT NO: GGGTGGCACGTGCCTGTTGGTCTCAGC 2331 MAPK1 ADXCRAD_BQ889971_x_at AAAAGTAGCCGGCCGTGGCGGTGTGCGCCTGTGG SEQ ID NO: 2332 SEPT7 ADXCRAD_BF855173_at AAGGTACTTAGAGCTCTTACTTTCTAAGTACAGAACACCCTAGACAATTCAAGGCATCTT SEQ ID AATCTCCATCAAGAACAAAAAAAAAAATAATTTTGGTCATGCGGTTAAATCCATCATTAG NO: GGATAAAACGGGTGCAAATGGGTCAAAGGGATCCAACAAACACGGATGTCCAAGCGGGCA 2333 TATGGGCAACTATTACGTTAACGGGGGGTCAATAGAGAGTTAAAAAGATCTTCCCTTTCT TCTGGTTCTTTTCCAGGGTTCTGGAAGAGTTCTGGT PDLIM7 ADXCRD_BU927740_at AGGCAGGAAAAATCGCTTTGATCCTGAAAAGGTGG SEQ ID NO: 2334 WDR1 ADXCRAD_CV811638_s_at GGGACTAGAGTTTAACTGCAGCGGAACATGTCATTTCTCTATTTCTGTGACGCGCCCCCA SEQ ID TGCCCCCACCCCACCACAAGAGGCAGGAGGGCCCAGTCATGACCCTCGTCTCTGCAGGGT NO: GTCTGTACACGTTCTTCTGAAAGCTTTAGACAGTAACAGTTTGCACATGAAAAATAAAGC 2335 GAGCACCTAAACAATGTGGTGGAGCATAACTAAAACCCACAGCCC YWHAZ ADXCRAD_BM461687_s_at TGAATGGACTTTTCAACTACTTTCTCTACAGCTTTTCATGTAAATTAGTCTTGGTTCTGA SEQ ID AACTTCTCTAAAGGAAATTGTACATTTTTTGAAATTTATTCCTTATTCCCCTCTGGNCAG NO: CTAATGGGCTCTTACCAAGTTTAAACACAAAATTTATCATAACAAAAATACTACTAATAT 2336 AACTACTGGTTCCATGTCCCATGATCCCCTCTCT SPTBN1 ADXCRAD_BI823572_s_at TTAAGACTGATTCTGGAGGTCCATCAGTTCTCAAGAGACGCCAGTGTGGCCGAGGCCTGG SEQ ID CTGCTTGGACAGGAGCCGTACCTATCCAGCCGAGAGATAGGCCAGAGCGTGGACGAGGTG NO: GAGAAGCTCATCAAGCGCCACGAGGCATTTGAAAAGTCTGCAGCAACCTGGGATGAGAGG 2238 TTCTCTGCCCTGGAAAGGCTGACTACATTGGAGTTACTGGAAGTGCGCAGACAGCAA CALU ADXCRAD_BP380290_s_at GAATGCTGATGGTTTCATTGATCTAGAAGAGTATATTGGTGACATGTACAGCCATGATGG SEQ ID GAATACTGATGAGCCAGAATGGGTAAAGACAGAGCGAGAGCAGTTTGTTGAGTTTCGGGA NO: TAAGAACCGTGATGGGAAGATGGACAAGGAAGAGACCAAAGACTGGATCCTTCCCTCAGA 2344 CTATGATCATGCAGAGGCAGAAGCCAGGCACCTGGTCTATGAATCAGACCAAAACAAGGA TGGCAAGCTTACCAAGGAGGAGATCGTTGACAAGTATGACTTAT FLNA ADXCRAD_CN332899_at TGACCTCTCGGCTTTCACTTGGGCAGAGGGAGCCATTTGGTGGCGCTGCTTGTCTTCTTT SEQ ID GGTTCTGGGAGGGGTGAAGGATGGGGGTCCTGTACACAACCACCCA NO: 2347 FLNA ADXCRAD_CN332899_x_at TGACCTCTCGGCTTTCACTTGGGCAGAGGGAGCCATTTGGTGGCGCTGCTTGTCTTCTTT SEQ ID GGTTCTGGGAGGGGTGAAGGATGGGGGTCCTGTACACAACCAC NO: 2348 EPAS1 ADXCRAD_BQ228942_at TTTCACTCTCCTCCGTCTGGTTTTGGCACTAGGTATTTCTAACGCCCGCGACACTAATTT SEQ ID ACAAAATGGGAATTTACCTGGCGAAAACTTGCCCACGGCTCACCCAAGCAAGGGGCCTTT NO: TTTTCTGGAGATGGCTCCCTTTAATTATCCCCAATTTTTTAAAGGGACCCCACTTGGTTT 2349 AAGCCTGGTTTCTAAAAAGGTGCCTTAAAATTTGTGGAGGGATTTTTTTTTCCCCCCCAC CCCTCCAAAGGGCTCTCCAGCAGTTCAAATTAGCCCGGCGGG CD59 ADXCRAD_CX784253_s_at GAGCTAACGTACTACTGCTGCAAGAAGGACCTGTGTAACTTTAACGAACAGCTTGAAAAT SEQ ID GGTGGGACATCCTTATCAGAGAAAACAGTTCTTCTGCTGGTGACTCCATTTCTGGCAGCA NO: GCCTGGAGCCTTCATCCCTAAGTCAACACCAGGAGAGCTTCTCCCAAACTCCCCGTTCCT 2353 GCGTAGTCCGCTTTCTCTTGCTGCCACATTCTAAAGGCTT CD59 ADXCRAD_CN431378_s_at GATAGCAGGGCATGAAAACTTAGAGAGGTACAAGTGGCTGAAAATCGAGTTTTTCCTCTG SEQ ID TCTTTAAATTTTATATGGCTTTGTTATCTTCCACTGGAAAAGTGTAATAGCATACATC NO: 2354 CD59 ADXCRAD_BP343697_s_at TGCTAACTCCTAGCTGACTCAGCATAGATTGTATAAAATACCTTTGTAACGGCTCTTAGC SEQ ID ACACTCACAGATGTTTGAGGCTTTCAGAAGCTCTTCTAAAAAATGATACACACCTTTCAC NO: AAGGGCAAACTTTTTCCTTTTCCCTGTGTATTCTAGTGAATGAATCTCAAGATTCAGTAG 2355 ACCTAATGACATTTGTATTTTATGATCTTGGCTGTATTTAATGGCATAGGCTGACTTTTG CAGATGGAGGAATTTCTTGATTAA CKAP4 ADXCRAD_CX752475_at AGCAGATTACCTCAGAATCCTGTCTGGTGGCAGAATTCAGTAAAAAAAAAAAGTGGGTGG SEQ ID GGGACCTTTCTTTCAGTGCTTAAGAAATATTTACTTTTTTGTCTGCGAATTTTGAATACC NO: CATGCTCATTGACGTTAGCCAACGCCCTTATAGAGAGACTGGCTCTGAGATCCGTAGGCC 2356 CAGGCGCTCTCACTTGACAGATACCGGTAGG RRBP1 ADXCRAD_CB159041_at TAAACACTATCCTGGGCGCAGCCCCGGGCCACCGCCGAGTGACGCCAAAGCCCTGGTTGA SEQ ID CTCTGACAGCCCCGTGGGTGTGTGGGAGGCCGGGCGCTCTGGGGTCTGTCTGTCAGT NO: 2360 RRBP1 ADXCRAD_CB159041_s_at AAAGCCCTGGTTGACTCTGACAGCCCCGTGGGTGTGTGGGAGGCCGGGCGCTCTGGGGTC SEQ ID TGTCTGTCAGTGCAATCGTTTAGTGTTTTTTCAGTGGGGCGGGGCGGGAAGCGGGTGGGA NO: CCGGGCAGCCAGTTCTCAAAGGCTGTGGGGCCGACTGGAGGCCACAGCCCCTCACCCCTA 2361 GACGTTGCCAACCAGAACTGACGTG RRBP1 ADXCRAD_BQ778389_at TGGTGGTGAGTTTTCGCCATCTCCTTGCGCTGGTTGGCTAGGGCTTCTTCATATGACGTT SEQ ID TCCTTCATGGAGAAAGTCGACACCAGGAAGATGCCAATGGCAGAAACAACCATGAATCCT NO: CCAAAGACCACAACCCCCAAGGTTTGAGTGTCGTAAATATCCATCCTGGCTTGCTTTC 2362 RRBP1 ADXCRAD_BQ931525_at CCATGAGAGAACAAGTCTCCTTAGAGCCACAAGAAGTAGACCCTTCCCAGAGCCCCCAGT SEQ ID TTTGTAAAATGAAACCCTGTGCTCCCCATTTT NO: 2363 RRBP1 ADXCRAD_BQ931525_x_at CCATGAGAGAACAAGTCTCCTTAGAGCCACAAGAAGTAGACCCTTCCCAGAGCCCCCAGT SEQ ID TTTGTAAAATGAAACCCTGTGCTCCCCATTTTGGATAAACCACTAATCCCG NO: 2364 ATP1B1 ADXCRAD_BP311263_s_at GAAGTTAAGAGCTGATCACAAGCACAAATCTTTCCCACTAGCCATTTAATAAGTTAAAAA SEQ ID AAGATACAAAAACAAAAACCTACTAGTCTTGAACAAACTGTCATACGTATGGGACCTACA NO: CTTAATCTATATGCTTTACACTAGCTTTCTGCATTTAATAGGTTAG 2367 FHL1 ADXCRAD_CX872156_s_at CACTTACCAGGATCAGCCCTGGCATGCCGATTGCTTTGTGTGTGTTACCTGCTCTAAGAA SEQ ID GCTGGCTGGGCAGCGTTTCACCGCTGTGGAGGACCAGTATTACTGCGTGGATTGCTACAA NO: GAACTTTGTGGCCAAGAAGTGTGCTGGATGCAAGAACCCCATCACTGGG 2369 PPP4R1 ADXCRAD_BG291984_at CCCACAGTACCGAGAAACACAAGAGGCACAACACACAAGACCAAGAACACAAAGGAGGGC SEQ ID GGGCGCCACAAAGTAGACACCAAGCAGGAGGCGACAAGAACACAGGACCACAGAGTGTAC NO: AAAAAAGAGGCCCTACATAGCGACAGAAATACACGAGAGCAGACGGGCCCGAGATCACAC 2370 GCAGACGGCGAAAAGCAGAGTGGGGCCTGAGAAGACACATCCCGCGGGAGATCACAGACC A MARCKS ADXCRAD_CD110028_at CAACGGCAGCGTCCCGGCCCGCCGAACAAAGAGGAAGCCCGCGGGCCGCCGGGAAGCGGG SEQ ID GGGCGGCCTTCACCCCTCCCTCGGGCCCGAAAAAAGGGTGAAGTCGGGTCCCGCCGAACC NO: GCCATGCCCTCCCTAAAGG 2374 MARCKS ADXCRAD_AV732105_at GAATGTACTTTGCTTTACAAAATGCTATAACTCTGCTTAGGNGTCTATTTTCTTGAGCCA SEQ ID CTAAAGCGAAAATAATGT NO: 2375 MARCKS ADXCRAD_AV732105_s_at ATTTTAAACTCAACCAAGCTGTGATAAGTGGAATGGTTACTGTTTATACTGTGGTATGTT SEQ ID TTTGATTACAGCAGATAATGCTTTCTTTTCCAGTCGTCTTTGAGAATAAAGGAAAAAAAA NO: TCTTCAGATGCAATGGTTNTGTGTAGCATCTTGGCTATCATGTTTTGGAAATACTGGAGA 2376 AGCTTTGACCAATT RYBP ADXCRAD_BM931122_at CTAAAGTGTCAGTTGGTGGTTTTGTGAACTGGTCAAAAATTCACAGGTCTTAAATGTTTT SEQ ID GGGGGAAATTTATATTGGACACTGCTCTTTGTCTAGCAAATAAAAGATGTTAATATATTC NO: CTGTTACTGGCATGTGCACGACTATGTTATTAGAAGCCACTTTATCATTTTCCTGCTTTA 2378 AATAGAAATGTCTATTTATGAATTCTGCTTGTAGTTTTTTCAC NR3C1 ADXCRAD_CA392568_at GTGCCTTTTATAGCTATTACTGTCTGGTTTTAACAATTTCCTTTATATTTAGTGAACTAC SEQ ID GCTTGCTCATTTTTTCTTACATAATTTTTTATTCAAGTTATTGTACAGCTGTTTAAGATG NO: GGCAGCTAGTTCGTAGCTTTCCCAAATAAACTCTAAACATTAATCAATCATCTGTGTGAA 2379 AATGGGTTGGTGCTTCTAACCTGATGGCACTTAGCTATCAGAAGACCACAAAAATTGACT CAAATCTCCAGTATTCTTG NR3C1 ADXCRAD_BQ433598_at GGTTACTTTCACATACAGCCCTCCCCCAGCAGTTGAATGACAACAGAAGCTTCAGAAGTT SEQ ID TGGCAATAGTTTGCATAGAGGTACCAGCAATATGTAAATAGTGCAGAATCTCATAGGTTG NO: CCAATAATACACTAATTCCTTTCTATCCTACAACAAGAGTTTATTTCCAAATAAAATGAG 2380 GACATGTTTTTGTTTTCTTTGAATGGGCTTTTGAATGTTATTTGTTATTTTCAGAATTTT GGAGAAATTATTTAATAAAAAAACAATCATTTGGCTTTTTGAATGCTC LDLR ADXCRAD_CX873479_at GAGGCAGAGCCTGAGTCACCGGTCACCCTTAATATTTATTAAGTGCCTGAGACACCCGGT SEQ ID TACCTTGGCCGTGAGGACACGTGGCCTGCACCCAGGTGTGGCTGTCAGGACACCAGCCTG NO: GTGCCCGTCCTCCCGACCCCTACCCACTTCCATTCCCGTGGTCTCCTTGCACTTTCTCAG 2385 TTCAGAGTTGTACACTGTGTACATTTGGCATTTGTGTTATTATTTTGCACTGTTTTCTGT CGTGTGTGTTGGGGATGGGATCCCAGGCCAGGGAAAGCCCGTGTCAATGAATGCCG CYP1B1 ADXCRAD_BQ939150_at CCGCGCAGCCGCCAAAGTCTCGAGGGCCACGTGCTGAGCGAAGCGCGCGAANCTGGTGGC SEQ ID CCTTCTGGGGGCCCGCANCGCGGACGGGGCCTTCCTCCGACCCAGGGCGCTGAACCGTCC NO: TGGCCGTGGCCAACCTCTTGAATGGCCGTGGGGTTTCGGCTGGCGCTAACNCCCCAACAA 2391 ACCCCAAGTCCCGGGGAGTCGCTCCCCCACACAACAAAAAG CYP1B1 ADXCRAD_BX104039_s_at AAAGCTGTGTTTATATGGAAGAAAGTAAGGTGCTTGGAGTTTACCTGGCTTATTTAATAT SEQ ID GCTTATAACCTAGTTAAAGAAAGGAAAAGAAAACAAAAAACGAATGAAAATAACTGAATT NO: TGGAGGCTGGAGTAATCAGATTACTGCTTTAATCAGAAACCCTCATTGTGTTTCTACCGG 2392 AGAGAGAATGTATT CRIM1 ADXCRAD_CD101810_at AAATAGAATTGACCTCCAGCCCGGATTAGGCATAAATTTTG SEQ ID NO: 2396 CRIM1 ADXCRAD_CD101810_x_at GGTGTTCTACCTGTTTGCATCAAAGGAAAAAAAGATTTTTTTTCCAAGGGCCAATTTTTT SEQ ID TATCTTTTCCCAAAAAAAATTTGTTAATGGAACATTTACAAAAATAGAATTGACCTCCAG NO: CCCGGATTAGGCATAAATTTTGGTTGGGA 2397 ACTB ADXCRAD_CD514490_x_at CACCCCACTTCTCTCTAAGGAGAATGGCCCAGTCCTCTCCCAAGTCCACACAGGGGAGGT SEQ ID GATAGCATTGCTTTCGTGTAAATTATGTAATGCAAAATTTTTTTAATCTTCGCCTTAATA NO: CTTTTTTATTTTGTTTTATTTTGAATGATGAGCCTTCGTGCCCCCCCTTCCCCCTTTTTT 2399 GTCCCCCAACTTGAGATGTATGAAGGCTTTTGGTCTCCCTGGGAGTGGGTGGAGGCAGCC AGGGCTTACCTGTACACTGACTTGAGACCAGTTGAATAAAAGTGCACACCTT LPP ADXCRAD_BM456598_at TTGTCTTGGAAGTATCTCATAGGTCTTTAAATGAGTAAAACATTTTTATGCCAGAAGGTG SEQ ID ATATAATGGATGTTAGTGTTTTTTATTGGATTTTACAGGAGTTTTAGTCAGATAATGAGG NO: ACAGAGACCTCCACTTGAATTCTTTACCACCATTTCAGCAATATTTTTTTAATGGCCTTT 2400 CACTTGGATTTTGGCTTAAATAAGGGCCCCGAACAAGATCCAAAACTTTGTGTCCTCAGG GAAGGGCCATTAATA LPP ADXCRAD_BM456598_x_at TTGTCTTGGAAGTATCTCATAGGTCTTTAAATGAGTAAAACATTTTTATGCCAGAAGGTG SEQ ID ATATAATGGATGTTAGTGTTTTTTATTGGATTTTACAGGAGTTTTAGTCAGATAATGAGG NO: ACAGAGACCTCCACTTGAATTCTTTACCACCATTTCAGCAATATTTTTTTAATGGCCTTT 2401 CACTTGGATTTTGGCTTAAATAAGGGCCCCGAACAAGATCCAAAACTTTGTGTCCTCAGG GAAGGGCCATTAATA LOXL2 ADXCRAD_CF619371_at CCATGGTGGGTCTGCCCGCCAGCTGGGCCTTGGGAATTCGCCCACCAAACGCCTTTCAAG SEQ ID AAAACCTTGGTTATTGGGCCCCGGAAGATGTTCAACAGCCCAACAA NO: 2405 BCL6 ADXCRAD_BM454297_at GCGCCCCTTTTTTTATGTGACGAGCAAAACCCTCCTTTCTCCCTG SEQ ID NO: 2406 FNDC3B ADXCRAD_CK126145_at TTTCATAGTGTCACCTAATCTGCGTAAAGCCGCCGCTTCCTTTATGAGGGTAATGCTTCA SEQ ID GCAACTGATAAATACTTGATGGTTGGACAACCCACTAAAGCATGAAAATGTTTTTGGAAT NO: TGGAGCATGCTTATGACCTAAACGCAAAAATTAACACATGCTCTTTTTTCGT 2409 CAV2 ADXCRAD_BM804910_at TAAAAACAAAACCGTGCGCATTGTGGGCCCCCCTTT SEQ ID NO: 2412 ELF4 ADXCRAD_AW970249_at CCAGTTTATTAATGCCAGTTTCCCGATGGTTGGAAAGGAACCATTTTG SEQ ID NO: 2415 EPHA2 ADXCRAD_BU174123_at GACAGAGGGTGTCAAACATTCGTGAGCTGGGGACTCAGGGACCGGTGCTGCAGGAGTGTC SEQ ID CTGCCCATGCCCCAGTCGGCCCCATCTCTCATCCTTTTGGATAAGTTTCTATTCTGTCAG NO: TGTTAAAGATTTGTTTTGTTGGACATTTTTTTCGAATCTTAATTTATTATTTTTTTTATA 2416 TTTATTGTTAGAAAATGACTTATTTCTGCTCTGGAATAAAGTTGCAGATGATTCAAA CDC42BPA ADXCRAD_BM048315_at CTTTATAAGAGATCCTCTGTACCAAAACAATGA SEQ ID NO: 2417 CDC42BPA ADXCRAD_BM048315_s_at ATGAAAACAAAATGACTTGTCTTTTTATTTGATAGTGTAATATCATTCATTTTATAAATT SEQ ID TTTTAGGGTTTTTCTCGTTGTAATATTGTACAGTTTTGCATGGCCTGGTGTGATCATTTT NO: TTGGTTAGAATATAATGCTGACAAATGTGGATGGAGGGGAAGATACTGTTTAGCCTATCA 2418 CTCCTTATTTTATTTTGTTTGGTTTTATGCCCTCAGTG PHACTR2 ADXCRAD_BX119839_s_at AAGTCAGATGTAATGTGACCCTAGAAAACTGTAGCAAGCTTCAGAAATAAATCTTTTGAT SEQ ID CTTTCCCTATCTTGATTAGATCCAAAGTCAAAGCAACCATACTTCACCTAGAGAAGACAG NO: TATTGGCAATCATGACACCTGTAATAAAAACTTGAATCCAAAGTCAAAACTTAAGCAAGA 2420 TACAAATGTGCTGCCTGCAGTTAGTCCTGCATGGGAATAAGGACTAGTTAT ULK2 ADXCRAD_CK818454_s_at AGTTGGTGACCTAAAGGCTTGTTAGTGATGTGGAGTTCCTACATGCAGTGAGTGGAAAAT SEQ ID GAAGTTCGTTTTCTCTTAGGAAAATGGGCAGCTGTCTTCTGCCTAATGTGTATTTTTCAT NO: GTTAATTCTGACAGTTCACCAAATAGCTAGTCATGGAGAATGCAGGCAGTTAACTTAATA 2421 TCCCTCCAGGAATGGTTCTACGTTGTGTATTATTTGGTTTCTTTTACTTACCTGCTTGAA TACT AURKA ADXCRAD_BM790362_at GCCCTGACCCCGATCAGTTAAGGAGCTGTGCAATAACCTTCCTAGTACCTGAGTGAGTGT SEQ ID GTAACTTATTGGGTTGGCGAAGCCTGGTAAAGCTGTTGGAATGAGTATGTGATTCTTTTT NO: AAGTATGAAAATAAAGATATATGTACAGACTTGTATTTTTTCTCTGGTGGCATTCCTTTA 2422 GGAATGCTGTGTGTCTGTCCGGCACCCCGGTAGGCCTGATTGGGTTTCTAGTCCTCCTTA ACCACTTATCTCCCATATGAGAGTGTG F3 ADXCRAD_BU941055_at GGAATTGTTACTGGTGTACTTATTCTATCTTCCATTTTATTATTTATGTACAATTTTGGT SEQ ID GTTTGTATTA NO: 2425 F3 ADXCRAD_BU941055_x_at GGAATTGTTACTGGTGTACTTATTCTATCTTCCATTTTATTATTTATGTACAATTTTGGT SEQ ID GTTTGTATTAGCTC NO: 2426 LDOC1 ADXCRAD_CN356531_s_at GCCGTTCAGCCTGGTTAGTTTTCTACCTACTCCGAGTGTCCTCCCCTGCCCCACCAGATT SEQ ID GCTGCAGGGGCGCGGTGTGCCTGGCAGCCAAATTGTTGACACTTCTTTTTTCCTATGCAC NO: TGGTTTTACACAGCTGTCATTTTTCTTTCAAAATTGCAGCAGTCCCACAGATGTGTGCAT 2427 TTGGACAAATAGTACTTAAAAACAAAACAAACAAGCACTCAGCCCAGCTCCTCAATACTA CCTGGAAAAAGCATTGGCA CD44 ADXCRAD_BP233968_at TGAATGGGTCCATTTTGCCCTTCCATAGCCTAATCCCTGGGCATTGCTTTCCACTGAGGT SEQ ID TGGGGGTTGGGGTGTACTAGTTACACATCTTCAACAGACCCCCTCTAGAAATTTTTCAGA NO: TGCTTCTGGGAGACACCCAAAGGGTGAAGCTATTTATCTGTAGTAAACTATTTATCTGTG 2428 TTTTTGAAATATTAAACCCTGGATCAGTCCTTTGATCAGTATAAT PPIC ADXCRAD_AL540607_s_at GAAAAGTCATTGATGGGATGACAGTGGTGCACTCCATAGAGCTCCAAGCAACTGATGGGC SEQ ID ATGACCGTCCACTCACC NO: 2429 IL6ST ADXCRAD_AV662263_s_at CTGATGTAAGTGTTGTGGAAATAGAAGCAAATGACAAAAAGCCTTTTCCAGAAGATCTGA SEQ ID AATCATTGGACCTGTTCAAAAAGGAAAAAATTAATACTGAAGGACACAGCAGTGGTATTG NO: GGGGGTCTTCATGCATGTCATCTTCTAGGCCAAGCATTTCTAGCAGTG 2434 SPTBN1 ADXCRAD_CX872934_at ACTAGAATTATCTCAAACGTACAATATAATGTATTTCAGCAAAAAAAAAAAAAATTGAAA SEQ ID TTACAGATTATTTAAAACAGTATCAGTTTTCTATTCCTTCTTGTATACCGACATTCTTAA NO: CCGTCATAGCAGTTGATGCAAAAAAGCCGCATGTCGTGTGTTAGTAAGTGATGCCAGATA 2437 CAAATGGTTTGGTCTGTAGAGTTAATGTGGAGCTGCACTGTGGCTGCAGCAAGATCATAA TATGCGATCTGTTTAATAAAGGTTAGCC FOXN3 ADXCRAD_BP254636_s_at CATCTTGTGGCTCCCCAGTGGTCAGCGGAGACCCCAAGGAGGATCACAACTACAGCAGTG SEQ ID CCAAGTCCTCCAACGCCCGGAGCACCTCGCCCACCAGCGACTCCATCTCCTCCTCCTCCT NO: CCTCAGCCGACGACCACTATGAGTTTGCCACCAAGGGGAGCCAGGAGGGCAGCGAGGGCA 2438 GCGAGGGGAGCTTTCGGAGCCACGAGAGCCCCAGCGACACGGAAGAGGACGACA MXRA7 ADXCRAD_BX099460_at TGATCACCCCACTGGCAGGACAATTCACAGTTCTTGAGCAAACTGAGTTAGGGAGGGTAT SEQ ID GCTAACGACAGAACCTATGCAAGTTCTTAGAAATATTTTTTGTTTGCTGAAATAAAGCTC NO: AATCAACACACTACCTTAAAAAAAAGTGGGAGCAGTGGCATTTCCATGCCTCATGCTCAC 2442 CATCATGAGGTTAACTTCCCGCCGTCGCCTCTTGCCTGCCAGGGGTTTTTCGGGAGCCCC TCTCTGTTCCACTCTGATTCCTTTTGNTTCTTTGCTGACCATTCACTCTCTG NT5E ADXCRAD_BM704188_at GGAGAAAGCTCCCTCCGTTCTGATGCTTTTGAGCTTATCAGGGACACCCTGCAGCAGAAA SEQ ID TTCCAGCTGATCCTTCAGCCTTCAGAGTTGATGAGGTGGGGCTCACACACATCTGGATTT NO: GAAGAAGAATCGTGGGTTTCAAGAACTCTGTGGTCTCTTAAGCATTGGTATTCCACAGCT 2446 ACACTTCCCTGATACTTTGCACTCAGTAATGACAA PHACTR2 ADXCRAD_CA944993_s_at GTGGGTATAAATATCTACAAGTATACACACATATGTACTTGTATTCCACTATTGTAACCT SEQ ID GAAAGAAAGACTATGTATTCCCTTTTTTAATTCCGTACTGGTATTTGTGTTATTTAAAAA NO: GCAAAATTCTGCTCTATTTAGTTGTATAATATTAGAGGATACTTTGCTGTGCACAATTCC 2451 A CRIM1 ADXCRAD_AI651806_s_at ACATTTTCTTTTCACGTTAAGCATACTGGGTATCTGTGTCTTTCACAACAAGCATTTTTA SEQ ID AAAGAAAACTCAATGCACAAATGGGTTAATTAGTATAAAAGTGCTAAGGGCTGTTTGAAA NO: AGTTACCACTATAGTATACAGTCAGTTATATTTGAGGCATACTACAACAAACTTCCAGCT 2454 TATTGTGGACAATATTCCAGTAGTTGTTTCAAACCATTGTTTGAAAAAAAAAAAAAAAAA ATCCAGGAGCTGATTAGTGATGCAG CDH11 ADXCRAD_BG435621_at ACAAACTAGTGGTGGGGGCACAGCAGAGCCCACGAAAAGAAGTTTTGT SEQ ID NO: 2458 CD44 ADXCRAD_BM840380_s_at GAGATCACTTCCAGCCTAATGTGCATTTGGCTGGAATATGGTTGTCTCAGAATAACATCA SEQ ID TGCACTCGGGCTTTTATACTTCTGCCTTTAGGGGACTGTGGCAGCATGGCATGGGTCAAG NO: AAGTACTTCTCCTTCATCTTCCTTTGATGTCGGTAACTCATCCTTTCTGCACTGCGGGAG 2459 TTGTTAATGCTTTTGTGTCCTCCAGTTCACATGCTGATTGCTAAGAAGAAAATGAGCATG AGTGAACCCAAAGCTGCTGAAACATTCTGCGTTTATGCAACTTCCTTG P4HA1 ADXCRAD_CD013931_at ATGACAGATGATTTTGTTCAGGAATTTTGCTGTTTTTCTTAGTGCTAATACCTTGCCTCT SEQ ID TATTCCTGCTACAGCAGGGTGGTAATATTGGCATTCTGATTAAATACTGTGCCTTAGGAG NO: ACTGGAAGTTTAAAAATGTACAAGTCCTTTCAGTGATGAGGGAATTGATTTTTTTTAAAA 2463 GTCTTTTTCTTAGAAAGCCAAAATGTTTGTTTTTTTAAGATTCTGAAATGTGTTGTGACA ACAATGACCTATTTATGATCTTAA PRSS23 ADXCRAD_BU164591_at AAAAAACTGGGCTGTTCAATCTCCTTTCCATTTTTAAAAACCTATTTTGAAAAAAGCTAA SEQ ID AAAAAAACTATTATGGCCTCCCTTTAGGGGGGGTTTATTTTTAATCCCCCGCTTTTTTTA NO: TTCACTTTTTAAAAATTAAAAAGTTAAAAAAAAAAATGGAAGCACCCCTGGCTAAAAAAT 2464 ZNF264 ADXCRAD_BM504879_s_at GTGTGTGTACATATGGACCACTTCAAGCTACACACACACACACACACACATATACACGTG SEQ ID TATGAATATATATATATGGCTATAAGTGGTGCGACTTGCAGGTACTCCCTTTGTTCACCT NO: TTGTAAAGATGTTATTGCCAGTTCAGTGTGTATTTCTATAGTATATATGTAAACAATTTG 2465 TCATCCTTTTGTTGCTGCTTTTGAAACTAGTTCATGGCTTCAGTGG MALT1 ADXCRAD_BU164882_s_at ATTTTAGTAGAAGTAATGTGCCAGTAGAGACAACTGATGAAATACCATTTAGTTTCTCTG SEQ ID ACAGGCTCAGAATTTCTGAAAAATGACCTCCTTGTTTTTGAAAGTTAGCATAATTTTAGA NO: TGCCTGTGAAATAGTACTGCACTTACATAAAGTGAGACATTGTGAAAAGGCAAATTTGTA 2466 TATGTAGAGAAAGAATAGTAGTAACTGTTTCATAGCAAACTTCAGGACTTTGAGATGTTG AAATTAC FLNB ADXCRAD_BP358943_s_at TGCTATAGCGCCATTCCCAAGGCATCCTCGGACGCCAGCAAGGTGACCTCTAAGGGGGCA SEQ ID GGGCTCTCAAAGGCCTTTGTGGGCCAGAAGAGTTCCTTCCTGGTGGACTGCAGCAAAGCT NO: GGCTCCAACATGCTGCTGATCGGGGTCCATGGGCCCACCACCCCCTGCGAGGAGGTCTCC 2468 ATGAAGCATGTAGGCAACCAGCAATACAACGTCACATACGTCGTCAAGGAGAGGGGCGAT TATGTGCTGGCTGTGAAGTGGGGGGAGGAACACATCCCTGGCAGCCCT ACTN1 ADXCRAD_CX871590_s_at TCTCCTGCCTGGGTTCGGTTTCAGCTCCCAGCCTCCACCCGGGTGAGCTGGGGCCCACGT SEQ ID GGCATCGATCCTCCCTGCCCGCGAAGTGACAGTTTACAAAATT NO: 2469 PTRF ADXCRAD_BU186765_at TTCCATTGAACCCAAAGGTCCGCAACACCTGCCTCCCAGGCCTGGGGCGGAAAAAATTGA SEQ ID AACACCTCCTCTCCACCTTGAATGGGAGCCTTCAAGGG NO: 2474 PTRF ADXCRAD_BU186765_x_at TCTACTAAGCCGAAACCCATCTCTACTAAAATTACCAAAATTTNCCTGGGCATGATTGCG SEQ ID CATGCCTGTAAATCCAGCTACTTTTGGAGGCTTGAGGGGGGCAGCAATTGCTTGAACCTG NO: GGGAAGGGGGCAGGTTTCCATTGAACCCAAAGGTCCGCAACACCTGCCTCCCAGGCCTGG 2475 GGCGGAAAAAATTGAAACACCTCCTCTCCACCTTGAATGGGAGCCTTCAAG FOXN3 ADXCRAD_BM995629_s_at CCGTGTAGGTCTATTGGCCAGCCAAGGTCAGACGACCCTAAGCATCAATAGTAAACCTCT SEQ ID TGGTCTTCTGATTGCTTTATCACTTTTTTTTTTTTTCTGTAAAACAAAACAAAACTCAGA NO: AATGTTACAGAATCAGAGTATTAAAAAATGTACAAGTGTATATGCTTCCCAGACACACAT 2480 GGATACATTTTTCCTCCACATTTTCACCATGGCAGTATTAAGTAGTGAGTGTGAATGACA CAGCATGAAACTGGTTACTGAATCAGCTATGAGCTCAGATGGCCTCAAC TUBB6 ADXCRAD_BP390113_at AACAGCAGAGAATTGCGGGTTCTACCCAGTCAGAAGATCACACCATGGAGACTTTCTACT SEQ ID AGAGGACTTGAAAGAGAACTGAGGGGCCACAAAATAAACTTCACCTTCCATTAAGTGTTC NO: AAGCATGTCTGCAAATTAGGAGGGAGTTAGAAACAGTCTTTTTCATCCTTTGTGATGAAG 2491 CCTGAAATTGTGCCGTGTTGCCTTATATGAATATGCAGTATGGGACTTTGAAATAATGAT TCATAATAAAATACTAAACGTGTGTCTTCAA NFIB ADXCRAD_BX442437_at TACAACAAAGTGACATCACTACACTTGTTTTGCTGCATTTATTATCATTTTAAATCTTTA SEQ ID CCATTTTTATGACAAAATATTTTGTACTCCAGACGAAGAAAAATGTGTGACATCATGGAT NO: TTTTTAGACAGTTATACCTTTATCTCMCATTTATAAAGCATATCATGGCTGTGTATAGTT 2492 GC NFIB ADXCRAD_BU902064_at ATGTTGGTTTAACTGCACCCTCCTGNAGGTAGATTTATTTATTAAAAATACTGGTTGCAT SEQ ID CAAGACCCATAGGGTGTACAAAAGGTCTATAAAATCTGCATTATAGAGAAAAAGAGGCAN NO: GCAAATCCATGTCCCAAGGTAAAAGCTACAGTTTACAACTGGGAACCCCAGGGTGAAGAT 2493 ATAAAACCCCCTCTTGAAAACAAATTGAAACAGGGGCTGAAAACTTGCGTGGGGCTTCAA AATTACCCTGGTCAAAATTTCCTGATTG GRB10 ADXCRAD_BG258819_at AAGATCAGCGGAAACGTTGAAAATAACTGGAATGATCATCTGGGGTGGGCCGCTACGAAC SEQ ID AGAACCGCAAACAGGATGGCATGAATCTTGCCCTGGATATCTGACATTACACGGACTGTC NO: ACTAACGATGACACC 2496 FHL1 ADXCRAD_BP361024_at GACTGTGTCAAGAGTGAGCCACCCAGTCTCTAAAGCTAGGAAGCCCCCAGTGTGCCACGG SEQ ID GAAACGCTTGCCTCTCACCCTGTTTCCCAGCGCCAACCTCCGGGGCAGGCATCCGGGTGG NO: AGAGAGGACTTGTCCCTCGTGGGTGGTGGTTCTTTATAGAA 2502 ACTB ADXCRAD_BM476291_at CCCAAGTCACACAGGGGAAGGTGATAGCATTGGCTTTCGGGGAAATTATGTAATGCAAAA SEQ ID ATTTTTTTAAATCTTCGGCCTAAATACCTTTTTTAATTTGGGTTTTATTTTGAATGGAGG NO: AAGCCTTTCCTGC 2504 ACTB ADXCRAD_BM476291_x_at CCCCACTCTCTCTAAAGAGAATGGCCCAGTCCTCTCCCAAGTCACACAGGGGAAGGTGAT SEQ ID AGCATTGGCTTTCGGGGAAATTATGTAATGCAAAAATTTTTTTAAATCTTCGGCCTAAAT NO: ACCTTTTTTAATTTGGGTTTTATTTTGAATGGAGGAAGCCTTTCCTGCCCCCCCCTTTCC 2505 CCCTTTTTTTGTCCCCCCAACTTGAGAAGGATTGAAAAGCTTTTTGGC WDR1 ADXCRAD_BE740367_at ATACCGGCTGGCCACGGGAAGCGATGATAACTGCGCGGCATTCTTTGAGGGACCCCCATT SEQ ID CAAGTTCAAGTTCACAGTTGGCGACCACAGCCGCTTGTCAACTGTGTGCGATTCTCTCCT NO: GATGGGAACAGATTTGCCACAGCCAGTGCTGACGGCCAGATATACATCTATGACGGGAAG 2506 ACTGGGGAGAAGGTGTGCGCGCTGGGCGGAAGCAAGGCCCACGACGGTGGGATTTACGCA ATTAGTTGGAGTCCCGACAGCACCCATTTGCTTT GRB10 ADXCRAD_BI833263_at GGGCGCGGCGCCAAAAAGCAGACCCCGAAGAGAGAGCCGCATAGGCACAAGAGGCCACAG SEQ ID CCAGATACCAACGGACAACAAGCTGGGCAAACAAATGGCGACACGACCGACGGAAAAAAC NO: CACGAGGAGACACAGCCAACCCAGACGACAAACCCGAGACACGCCGCCCACAAGACAGGG 2507 AACCACAAGCACCCCGACCGGGAGGCACACTCAAAGGACGCCGCACCCACCCACACAGGC AGGAGAGCGCCGACCGCGGCAACAAGAGCACCCAGA IL6ST ADXCRAD_AU280467_s_at GATAACAGTTACTCCAGTATATGCTGATGGACCAGGAAGCCCTGAATCCATAAAGGCATA SEQ ID CCTTAAACAAGCTCCACCTTCCAAAGGACCTACTGTTCGGACAAAAAAAGTAGGGAAAAA NO: CGAAGCTGTCTTAGAGTGGGACCAACTTCCTGTTGATGTTCAGAATGGATTTATCAGAAA 2508 TTATACTATATTTTATAGAACCATCATTGGAAATGAAACTGCTGTGAATGTGGATTCTTC CCACACAGAATATACATTGTCCTCTTTGACTAGTG CASK ADXCRAD_AW959845_s_at CTACATTCCGTTCATGGGGCACACCCAGGGGAATAAGAATAAAATGCTATTATGACTAAG SEQ ID TTGTAAACCTATGCACATCCCTTGCATTTTGGGCAACTTTAT NO: 2509 NFIB ADXCRAD_BP382229_s_at GAAGTCCAAGCCACAATGATCCTGCCAAGAATCCTCCAGGTTACCTTGAGGGTAGTTTTG SEQ ID TAAAATCTGGAGTCTTCAATGTATCAGAACTTGTAAGAGTATCCAGAACGCCCATAACCC NO: AAGGAACTGGAGTCAACTTCCCAATTGGAGAAAT 2510 VEGFA ADXCRAD_AI557291_at ATCCAGAAACCTGAAATGAAGGAAGAGGAGACTCTGCGCAGAGCACTTTGGGTCCGGAGG SEQ ID CGAGACTCCGGCGGAA NO: 2511 VEGFA ADXCRAD_AI557291_s_at ATTCCCGGGCGGGTGACCCAGCACGGTCCCTCTTGGAATTGGATTCGCCATTTTATTTTT SEQ ID CTTGCTGCTAAATCACCGAGCCCGGAAGATTAGAGAGTTTTATTTCTGGGATTCCTGTAG NO: ACACACCCACC 2512 LAMB1 ADXCRAD_CN388523_s_at GAAACCTTGTTCAACGCGTCCCAGCGCATCAGCGAGTTAGAGAGGAATGTGGAAGAACTT SEQ ID AAGCGGAAAGCTGCCCAAAACTCCGGGGAGGCAGAATATATTGAAAAAGTAGTATATACT NO: GTGAAGCAAAGTGCAGAAGATGTTAAGAAGACTTTAGATGGTGAACTTGATGAAAAGTAT 2513 AAAAAAGTAGAAAATTTAATTGCCAAAAAAACTGAAGAGTCAGCTGATGCCAGAAGGAA PLAU ADXCRAD_CX787154_at AGAGACTGGGAAGATAGGCTCTGCACAGATGGATTTGCCTGTGCCACCCACCAGGGTGAA SEQ ID CGACAATAGCTTTACCCTCAGGCATAGGCC NO: 2514 PLAU ADXCRAD_CX787154_s_at GCCAGGCGTCTACACGAGAGTCTCACACTTCTTACCCTGGATCCGCAGTCACACCAAGGA SEQ ID AGAGAATGGCCTGGCCCTCTGAGGGTCCCCAGGGAGGAAACGGGCACCACCCGCTTTCTT NO: GCTGGTTGTCATTTTTGCAGTAGAGTCATCTCCATCAGCTGTAAGAAGAGACTGGGAA 2515 MDFIC ADXCRAD_BE878413_at GGACACCATAGCAGACAAGATAAAGAGGCAAGAAATTGTCCACGATCAAAAAGAGACTAT SEQ ID ATACGACAGTGAGAAAGAGGGTAGCCTATAAGATAGCAAACGGAGGGTGACAACAATCTA NO: TTAATGAACAATATTTAACAGAGGGAGCACAAATAGCAGGATAAAACAACGGGTGAGAAT 2516 AAAAAAGTGGAGTAGAAAAAGAGATTAGTAGTACGAGAGAAAATAGGGGTGGAAAACCCA CAGTAATAGAACAA ZFP36L1 ADXCRAD_BU073871_s_at AATATATTATTCTTCAACGACATTTTTTGTAACTTTACACTTTTTTGGTTATTTTATTTT SEQ ID AAAAAAATGAAAAATTAATTTAAAAAAATGCAAAAAACTGTTGGATTATTTATTTTAGAA NO: ATTCCCCCCTTTGTGTTGGACTGCAAATTGAGTTTCTTTCTCTTTAGGCCTTTCACAACT 2519 AGGACTGAGAATGTATGTAAAAGTTCTGTGACAGTACAGAAGGAAAACAACTTTTTATGT ATAGCTTCTA LMNA ADXCRAD_BI770050_at AGAGAAGTTATTTTCGTACAGGTGGTTTTATACCTGAAGGGAATAAACGACAATGCAAAA SEQ ID ATAAACAGATCCGAGCCTCTATCTCAGTACATGTTGTCAGGCCGATAATGTCCGACCTCG NO: CGTTTCGTTTTGCCCGTGTTTCCCGTGAAGCGTCGGAATTCGGCCTTGAAAACCAATAAG 2520 GGAATTCCTTTAGAAGCCAGGGCTGAAAGGGGTAGCGTAAGTAAAGAGGTCAACCTGCGA GGTATCATGACCTTGTAGGTTGGCCCGC COL6A1 ADXCRAD_CX781062_at GGGCTCAGCCCTGAGTTGGCATCACCTGCGCAGGGCCCTCTGGGGCTCAGCCCTGAGCTA SEQ ID GTGTCACCTGC NO: 2521 CDC14B ADXCRAD_BM842156_at ACGCCCGGGAACACACACTGTGCTGGGGAGGAAGTGGGCCTAGGAGGGCCTGCAGGTCCA SEQ ID GGCAGCTGTAGAGCTGCTAGAAGCTGGGGTGTTGCTCTCCCCGCTTTCTCATAGACACAG NO: AGGTACTGTCTGCCTGTTGTCACACAGTTCATATGCTCGCTTGAGATGGAATCTGAACCT 2522 TGGTCCCAGGATCTGTGCTTTTTCCCACTTTGCCACACTGTCTAAGGTGGCTTTGAACTG GAACCCAAGTGCAAATAAAGGTTGGTATTCGCTCCT ATP2B4 ADXCRAD_CN299966_at ACAAATGGTGATATCAAAGCAACGTATACCCCAGTCCAGTGTGTGTTGCCATAATTTGCA SEQ ID ATTCAGCTTAACAGTGCACCCAATCTATATTTGCATTTTG NO: 2523 IGFBP3 ADXCRAD_CD512795_at AGCTCTTTAAAGGGCAAAAGCTTATTTCCACTNCTCATCCTTTTGTCCTCCTTTAGCACA SEQ ID ATGGTAAAAAAGAATAAGTAATATCCGAACCAGGGAAGGGAGGGAATGGGCTTTGTCTGG NO: GGGAAGCCCAATCCAGGGACAA 2524 IGFBP3 ADXCRAD_CD512795_s_at GACAGGGAGAGTCAGCCTCCACATTCAGAGGCATCACAAGTAATGGCACAATTCTTCGGA SEQ ID TGACTGCAGAAAATAGTGTTTTGTAGTTCAACAACTCAAGACGAAGCTTATTTCTGAGGA NO: TAA 2525 KCTD12 ADXCRAD_BQ881289_at TTTGTTTAATACATGTGGACCATGAACAGTATTCATTCTCCTTTTTCAATGATATGCTGT SEQ ID AGAAAATATTCCTTGAAGATGTGAGATTTAAAAATTTTTCCCTTTCAATGTTGGTTTAAT NO: TGAATTTCCTAACTTGGGTTTTTTTGATTGATAGCCCAGTGATAAATCCTAATACTAGAC 2526 AAAATTTGTCTTCTCTTTTTCAACCAGAGCCCAAATATAATGGCCTGGAATAAAGGGGAA CCTTACTGCCTTCTCTTTGA KCTD12 ADXCRAD_BQ881289_x_at CATGTGGACCATGAACAGTATTCATTCTCCTTTTTCAATGATATGCTGTAGAAAATATTC SEQ ID CTTGAAGATGTGAGATTTAAAAATTTTTCCCTTTCAATGTTGGTTTAATTGAATTTCCTA NO: ACTTGGGTTTTTTTGATTGATAGCCCAGTGATAAATCCTAATACTAGACAAAATTTGTCT 2527 TCTCTTTTTCAACCAGAGCCCAAATATAATGGCCTGGAATAAAGGGGAACCTTACTGCCT TCTCTTTGAGGAAA MAPK1 ADXCRAD_CX757452_at TTCAGTGTTGCTTTCCTCTTGATCAGCGTGTCTGAATGACAGTCAGGTTCAGGTGTGCTG SEQ ID ACACAGAATGCTCACAGGCTCACTTGCCG NO: 2531 RRAS2 ADXCRAD_CX788826_at GTTTGCCAAGCTGAAGCTACAGGTTGTGAAATAATTTTTAACTTTTGGAATCATACTGCC SEQ ID TACTGTTACTCTAAATAGAAATATAGGGTTTTTTTTAATGTGAATTTTTGCCTATCTTTA NO: AACATTTCAATGTCAGCCTTTGTTAACCTTAAATACACTGAATTGAATCTACAAAAGTGA 2536 ACCATCTCAGACCTTTACTGATACTACAACTTTTGTTTTCTGATGGCCAAAATACCAAAT GCCTGTTGTATTTATGGATTAAA ARID5B ADXCRAD_BG285011_at CTCTATGCTCTGTAAGGTGATTATTTGTATATAGCAACATGGCCCAGTGATATTATATAG SEQ ID TTTCCCAATGGAGAGGTTATTGAGTAACCTTTGCATTAGTTTAAACACTACCAGAAGAAT NO: GCTGAGCCAACTATAAACACTCAATTTTGTATGTTTTCCAAATTGGTACTTATTACTGCT 2537 TTTGATACTGTATTACGTGCCAATAGTTTCCCAATCACATAGCAGGCAAGAGATATTTTG TACTTTCTGATCCACTGTAATATTTA NFIB ADXCRAD_CA430617_at GCCTGTTCAATTTCACAGTCTCTGTTGAGTTCAGTTGTAAATATGTTTCAAATGACATTT SEQ ID TCTTGGGAAAAAAAATCTCTACAACATTGTAGAATGTGAGGGGTAACTACATCCCAGGCA NO: TAGGTTTCTCAAAGCTGCAGTAGATTATGTCTTCATCAAGCTGTTAATTTGTGCTTATAT 2542 CATATAGAACTTTTAGCATCCTG NFIB ADXCRAD_BQ068224_s_at TATGGCTTTTTATGCATCCTTCATCGAGGGCATTGAAGTTGCATGGACTGATAAAAGTTG SEQ ID ATGCNAAACAAGAAAGAAACAAACAAAAAAAAAAAAACCAGCAAAATGTTTACCCAAAAA NO: CTCAAACAAATGAGCAGTGCCTGTT 2543 CREB3L1 ADXCRAD_BM850478_at CCCACTGTACAGAGACCAAGAACAGAAATTGTTTGTAAATAATGAACCTTATTTTTTATT SEQ ID ATTGCCAATCCCCTAAGATATTGTATTTTACAAATCTCCCTCTTCCCTTCGCCCCTCCCT NO: TGTTTTATATTTTATGAAGTTAGTGCGGGCTTTGCTGCTCCCTGGCCCAGGAAAGAGGGA 2546 CTCCCTGACCCTCACCTGGCACCCCCCTGCTGCTGCCCAAGCCGCTGGGCCTTTTTAATT GCCAAACTGCTCTCTTCATCAGCTCAGCACATGCTTTAAGAAA TUBB3 ADXCRAD_CX870071_at GAAGGTGGCCGTGTGTGACATCCCGCCCCGCGGCCTCAAGATGTCCTCCACCTTCATCGG SEQ ID GAACAGCA NO: 2550 TUBB3 ADXCRAD_CX870071_x_at GTGGATCCCCAACAACGTGAAGGTGGCCGTGTGTGACATCCCGCCCCGCGGCCTCAAGAT SEQ ID GTCCTCCACCTTCATCGGGAACAGCACGGCCATCCAGGAGCTGTTCAAGCGCATCTCCGA NO: GCAGTTCACGGCCATGTTCCGGCGCAAGGCCTTCCTGCACTGGTACACGGGCGAGGGCAT 2551 GGACGAGATGGAGTTCACCGAGGCCGAGAGCAACATGAACGACCTGGTGTCCGAGTACCA GCAGTACCAGGACGCCACGGCCGAGGAAGAGGGCGAGATGTACGAAGACGA CREB3L1 ADXCRAD_BU528167_at GATTCAACTGCCCACGGATTCAAGCCAAACCCTCTGGAAGCGGAACCCAGTTCCTCCAAG SEQ ID TGACACCCGGAGGAACTGGTGCCAGATGCCTCCGACGCCCCCCCATAGACCATGGGCAGG NO: GACAGCGAACGGGTTCCCAGAAGTCCCCCGCTTTCTTTGCCCCCCCTACGGGCCCTGTTC 2552 AAGGGCCATGG PDLIM7 ADXCRAD_CN278331_at TCTGCCCACGTGCTCAACGTGCAGTCGTAGCCCGGCCCTCTCCAGCCGGCTGCCCTCTCT SEQ ID GCCTCCCTCTTTCTGTTCCTCCTGCCCAGGGCACCCCCTTAGTGCCTCCAGCTTCTGCCT NO: ACCTCACCCCCCCTTTCGTGCCCCTGGCCTGAGCCTCCTGCTGGCCTGGCCCTGGCCGCC 2560 CACCTGGGTTCATCTGACACTGCCTTCCCTCTTTGCCCTGTGGTACTGCTGTCTGCCAGG TCTGTGCTGCCTTGGGCATGGAATAAACATTCTCA PDLIM7 ADXCRAD_CN278331_x_at TCTGCCCACGTGCTCAACGTGCAGTCGTAGCCCGGCCCTCTCCAGCCGGCTGCCCTCTCT SEQ ID GCCTCCCTCTTTCTGTTCCTCCTGCCCAGGGCACCCCCTTAGTGCCTCCAGCTTCTGCCT NO: ACCTCACCCCCCCTTTCGTGCCCCTGGCCTGAGCCTCCTGCTGGCCTGGCCCTGGCCGCC 2561 CACCTGGGTTCATCTGACACTGCCTTCCCTCTTTGCCCTGTGGTACTGCTGTCTGCCAGG TCTGTGCTGCCTTGGGCATGGAATAAACATTCT PDLIM7 ADXCRAD_CD366841_at GATGCGGAAGGAACGCGACTGGCCTGTCCCCGGCCGCGGCCGCCAGTCCTCTGTGTTCTC SEQ ID CATCAGCCGCTGCTTGCTGGCATCTGGGACCAGCGGTCGGAGCGGCTGTCCATTCTGCTG NO: CGGGGCGCTGT 2562 PDLIM7 ADXCRAD_CD366841_s_at CTGTGTTCTCCATCAGCCGCTGCTTGCTGGCATCTGGGACCAGCGGTCGGAGCGGCTGTC SEQ ID CATTCTGCTGCGGGGCGCTGTCAGCGGGCGGGGGCGCCCCANAGGGCCGGGCCGTCTTGT NO: TGAGGGAGACGCTGGGTGCACAGGTGTACCGCGGAGGGTCCGCGGCGGNGGCGGAGGCCT 2563 TCTGCGGTTTGCTCTGAACCGGCTGGGCCCTGCTGAG PDLIM7 ADXCRAD_CD366841_x_at GGAAGGAACGCGACTGGCCTGTCCCCGGCCGCGGCCGCCAGTCCTCTGTGTTCTCCATCA SEQ ID GCCGCTGCTTGCTGGCATCTGGGACCAGCGGTCGGAGCGGCTGTCCATTCTGCTGCGGGG NO: CGCTGTCAGCGGGCGGGGGCGCCCCANAGGGCCGGGCCGTCTTGTTGAGGGAGACGCTGG 2564 GTGCACAGGTGTACCGCGGAGGGTCCGCGGCGGNGGCGGAGGCCTTCTGCGGTTTGCTCT GAACCGGCTGGGCCCT LMNA ADXCRAD_AV703605_at TCTACCGCGGGTTTATACTGGATGAAAAACTCATGCCAACACCAAAAAGCAAACTCCAGG SEQ ID GGGTTCCCCGTACCCAATAGGGCCCATGGTGAGTCGGCCCACAATTAACTTGCCCTTCTA NO: TTACAACCGTCTAGTCTTGCGAAAACCCCTGCGGTTACCCACCCTAAATGGCCTTGCAGA 2565 ACTTCCCCCTTTTGCCCGATTGCCGTAACATCCAAACAGGCCCCTACCGATCTGCCCTTC CAACAAATGGGCAACCCTTAATGGGCGAAT CDC42BPA ADXCRAD_BU508210_at GAAATTTTGAATAACCTATATACACAAATAAAAACACGGGCAGGCCGCCTCTTAGAAGAA SEQ ID TTCCCTCCAAGGGGGCCCAAACTTTACGCGGTACCCCACCTTTTCTTTGGTAAAAAGAGG NO: GGCCCCCTATTAGAGGAGCCGGCATTTTTAACGTTAAGGGACTGGGGCCGGACTATTTTA 2567 TAAAGTCTGTGGTAACTGGGAAAAAACTGCCCAACCTTGGGAAACCTTTCGTGAAAGGAA AACTTTTACTTTTGGGGGGTGAGCGCAATAATATGTGGCCACACACTTCCTTCC MAP1B ADXCRAD_BG164365_at TTGGGCCCCATTTCAGAAAATCTCAGACTCTAAACCACCAGTGATTGCCCTAGCATGCTC SEQ ID CAGAATTGTCCCGCACTTAGTCACTCTGGTTCGATTACTGTTGCGAAACCAGTCCCCCAT NO: TATGACAATACCCAGCGGGGTCTTTGGTAACATGGCCGAGATGAATCAAAACGGGCCCTT 2568 CGGGCACGTTAAACCTGCTACTAAACAGGATGGGTAAAACACTCCAGGCAAACACCAGCG AAAGATT IL8 ADXCRAD_BG340548_at ACTCTGGACATCAGCAGCACGCGGGGCTTCCCATTCAGTCCTGAGAGGGGGGGAAGTACG SEQ ID GCAGCCACCTCTCACAGGTGGCTGGTGCTTCCAAGGAGGTCATGCCGGGCACACGCCAAC NO: CCGTGGTGTGCGCAGTCACGCCCCGAGGACAAGAAAAAACGGCCTTCCACTGTTGGCTGA 2570 GCTGC S100A10 ADXCRAD_BG675291_at TGACTTTCAATTCCTGGCCGTTGGTCTGTTGTTCTCAAGAATTCCAAAAGACCCTCTTTG SEQ ID GTGGTGGGACCAACACATATGTAAGGCACCGTGCAACCAGGTTTAATCGAAGTGACCAAG NO: TGAGGGCATCACGAAAGCTTTCTTCACCCCCATAATGGGAGGGCAGCACACAATAGCTGT 2579 CAGACACCTATTGGTGACGTCACCCTGCTACGGACGGGCAAAAAATTCGCACACAATCGA AGAACCCACCTCCTGATAGAAGTTTCCCAGACGCTCGTTAGAATCGTGCCCA RAB31 ADXCRAD_AL552789_s_at GACCGACTGGGTATCTAGCTTACTGTTTTAACATCATTGTTGAAACCAGACCCTGTAGTC SEQ ID CAGTGGTGCTGCCCTGTTGTGCAAACTGCTCCTTTTTCTCGTGTTTTTGTAAAGAGCTTC NO: CATCTGGGCTGGACCCAGTTCTTGCACATACAAGACACCGCTGCAGTCAGCTAGGACCTT 2580 TCCGCCATGTATTCTATTCTGTAGTAAAGCATTTCCATCAACAATGCCTAATTGTATCTG TTATTTTTGGTTTAACACACACTGATTCATACT GALNT2 ADXCRAD_CO405530_at GCAACTGAGTGACTCTCACCTACCACCGACTGGGGAGTGGTAAAAGCACTTGACGGATGC SEQ ID CTGGCAACTTAAGACCTGCTGGAAGAGGGGCACAATGCCCCCGGAGCGAGAAAACCCTGA NO: ATCTCATTTCATCCCTTCAATCCGTATGTTTCACAACCCCAACTTTCACTGGCAGTTACT 2581 TAAAGTCCTCTCCTGCTCTCTTCCAAGTGTTCTAGGCAAACCCTC MVP ADXCRAD_BP354622_s_at CTTGTGAGCCCTGGGCTTAGGAGTCACCATGGCAACTGAAGAGTTCATCATCCGCATCCC SEQ ID CCCATACCACTATATCCATGTGCTGGACCAGAACAGCAACGTGTCCCGTGTGGGAGGTCG NO: GGCCAAAGACCTACATCCGGCAGGACA 2583 PTPLA ADXCRAD_CD299090_at ATCTCTGCAAAACAAGTGCTTTTTCCAGAATAACCAAGATTTACTGAGTCCAAGTTTTTA SEQ ID ATAACAAGAAATAAACAACCTTTGTGAAAATAATCATGGGATTGGTATGGGTTTT NO: 2585 PTPLA ADXCRAD_CD299090_s_at ATTATTTTCTTCTTATAACCATGGCATCATATATACCTTTGTTTCCACAACTCTATTTTC SEQ ID ATATGTTACGTCAAAGAAGAAAG NO: 2586 LRP12 ADXCRAD_BP368157_s_at GATTGTTTTCATCCTGATACTGTAGTTCACTGTAGAAATGTGGCTGCTGAAACTCATTTG SEQ ID ATTGTCATTTTTATCTATCCTATGTTAAATGGTTTGTTTTTACAAAATAATACCTTATTT NO: TAATTGAAACGTTTATGCTTTTGCCAACACATCTTGTAACTTAATAT 2589 MAPK1 ADXCRAD_AA467802_s_at CTCTCTCTGCAGGAGTGCTAATCACTGTGGCTTCTGTTAAGAATTCCCAACTTGATCTCT SEQ ID CTCCTGATGCTGCTGGAAGGATGGAACCGTCATCTCCTCCATCTGAATCACTGACAGGCA NO: TTCTTAGATTTTTAAATCAGGATGCTGAAAACTATCTTTGTCCCTTACCTCCACCTTCTT 2590 TTTGTACCTCCCAGACCCAGGCCCACCTCTCACGTTTATAAGGTCTAGGTCAAGAATACA AATGGAGCCCTACATACCATTA CD55 ADXCRAD_AA632649_at CATCAGAAAGATTCCCAGGCTGGCTACTTCGGGATGACCCTTGCATTTTTTATTGAAATC SEQ ID ATTTCTGAATCTTTTTTCCCCACTAGCTTTTAAGACATAGGAACTATATCTTGTTCAGCT NO: TTGCACTTCCAATTATAAAAAAATGCCTGGCGTGTGTTAGGCACTCAGAAAATGTTTGAA 2593 CTGAACCAATGGTGTGTGTGTCTCTGCACACTCTAAGTTAGTGTAAATCAGAACAGCTTG TTGTTGCTGCTTGTTTTGATCAAG COL5A2 ADXCRAD_CN415190_s_at TACAACAGTTTAGGTTTAAGATGACCAATGACAATGACCACCTTTGCAGAAAGTAAACTG SEQ ID ATTGAATAAATAAATCTCCGTTTTCTTCAATTTATTTCAGTGTAATGAAAAAGTTGCTTA NO: GTATTTATGAGGAAATTCTTCTTCCTGGCAGGTAGCTTAAAGAGTGGGGTATATAGAGCC 2594 ACAACACATGTTTATTTTGCTTGGCTGCAGTTGAAAAAATAGAAATTAGTGCCCTTTTTG TGACCTCTCATTCCAAGATTGTC NFIB ADXCRAD_AW975114_at CTGAGGGTTGGCATGAATGCTTTTCTTTTTCACGTGTAACATTAGGTTCAGACATATATG SEQ ID TGTGCAGTGCATTGCTGTAATGTGTGCACATGGTAAGAACACATATGTCTCAATACCATG NO: CTGTATCGCTCAATAGCCTGACAGATGTATATGGGTGAATTCATTCATTGCCCTCTCTGG 2598 TGATTAGTAGCACTTTGAAAATGATGTCGTAATTTGGCAAACT KCMF1 ADXCRAD_CN402369_at AAGACTGTTGACCACTTGAATTTCTTTGGTGTTAGTGGATTAACCTAACCATTACTCTGA SEQ ID GA NO: 2601 KCMF1 ADXCRAD_CN402369_x_at GGTCTTTCAAACACATCTGCACATAAGTCACACATTTCAATAAAGCATTTTCAAGACTGT SEQ ID TGACCACTTGAATTTCTTTGGTGTTAGTGGATTAACCTAACCATTACTCTGAGATTTTAT NO: ATCTCTAATCCAGTATTTTTTTTCTTTTTATGCTAAACATGGGAGATCCTGGTTTTGTGT 2602 GAATGCATTATTTTGGATGTGAGAAATAAATGCCAATTATATGTACTTTCCCTTTTCTGC ACAA ADAMTS1 ADXCRAD_CN354195_at CTGCCAGTTGCAAATTTGATAGGATAGTTAGTGAGGATTATTAACCTCTGAGCAGTGATA SEQ ID TAGCATAATAAAGCCCCGGGCATTATTATTATTATTTCTTTTGTTACATCTATTACAAGT NO: TTAGAAAAAACAAAGCAATTGTCAAAAAAAGTTAGAACTATTACAACCCCTGTTTCCTGG 2604 TACTTATCAAATACTTAGTATCATGGGGGGTTGGGAAATGAAAAGTAGGAGAAAAGTGAG ATTTTACTAAGACCTGGTTTA ADAMTS1 ADXCRAD_CN354195_x_at CTGCCAGTTGCAAATTTGATAGGATAGTTAGTGAGGATTATTAACCTCTGAGCAGTGATA SEQ ID TAGCATAATAAAGCCCCGGGCATTATTATTATTATTTCTTTTGTTACATCTATTACAAGT NO: TTAGAAAAAACAAAGCAATTGTCAAAAAAAGTTAGAACTATTACAACCCCTGTTTCCTGG 2605 TACTTATCAAATACTTAGTATCATGGGGGGTTGGGAAATGAAAAGTAGGAGAAAAGTGAG ATTTTACTAAGACCTGGTTTA PEA15 ADXCRAD_CN347927_at TGAACTGTCCTTCCATTTGGGATATGTTACATTAGAGTGAGAGAGAGAATAAGGAGCCTT SEQ ID TCTTATGGAAGAAATGGGAGAAGAGAGACAGGGTTCTTTTCAGCAGAGTCTAGTAGTTTC NO: TCTGTAAGGCAAAATAATCTAAAAAGACTAACCTGCCCACCCACTCCTTATATTGCTGTG 2608 AGATTGCCCCTATCTTGTGCTCTTCTGTCTGCAGTGTGCACGGCCTTGTTCTAACCC RRBP1 ADXCRAD_CN262594_s_at CACAGTGAAGCATCTCGAAGAGATTGTAGAGAAGCTAAAAGGAGAACTTGAAAGTTCGGA SEQ ID CCAGGTGAGGGAGCACACGTTGCATTTGGAGGCAGAGCTGGAAAAGCACATGGCGGCCGC NO: 2610 MARCKS ADXCRAD_CD103045_at TGAGGGAGGTTTACAGCACTACAGGTCTTGAGTTAAGAAGGAAAGAGGAAAAAGAAAAAA SEQ ID CCCCCATACCCCGATTTAAAAAAAAAAAAAACCGATCCTTAGTCTTTAGAAGTTCCATTT NO: AAACCCATAGGGAACCTTTTCCCCTTAATCCTCATGGTTAAGCCTGTACCCAGTTCCAG 2612 OPTN ADXCRAD_BQ719953_at TTTGGCTTCATTTAAGCTGTATACTTAGTCATATATCTTTCATTAGTTCTATGGATATGA SEQ ID GCAGATCCCTTTACTGGAGCCCAGTATGTGCTGTGTGAGTTAGAAGTCATTCTTGCTGAG NO: AAGGTGAATAGGTAGGGATTTGCCTTGTTTTGTAAGTCTACAATTTGCCAAGAGTAAATA 2614 ACACTGGACCAGCTGT LPP ADXCRAD_CX867590_at TCTTGATGGGCCTTTTGTCCCAGGACTTCCACATTT SEQ ID NO: 2618 YES1 ADXCRAD_BQ439982_at TTCTCATTGAATGCACCTATTAATCGTTTTAGTTGCTATTCATATTCTCATTCGTTTTTT SEQ ID AAAAATGATATATTCCTGATTTATTCTTCCATTGAGAAAAAATGTTCAGTTACTTGTAAC NO: TACTGAGCAGAATTAATCAATCCCTTTATAA 2619 PHACTR2 ADXCRAD_CA390198_s_at ATCCTTTAGTGCCTCAGAAGATGAAGGCCACAGGGAATACCAAGCCAATGACTCTGACTC SEQ ID GGACGGGCCTATCTTGTACACCGATGATGAGGACGAAGACGAAGATGAGGATGGCAGTGG NO: AGAAAGTGCTTTGGCAAGTAAAATACGCCGGAGGGATACTCTTGCTATCAAACTTGGCAA 2622 CAGACCATCTAAGAAAGAACTAGAGGACAAAAACATCTTGCAGCGTACATCTGAAGAAGA GAGGCAGGAAATCCGACAACAAATTGGA MARCKS ADXCRAD_BM557039_at AAAATAGCTTTTGAGGATTAACGCAAAAATAAAATAACTCCTTGTACCAGGTCCAGAAAT SEQ ID TGGCCTATTAAAACCTGAATTTGGGCAGTATTTTATAATGGGCCATTTGGCTTGTGGGTT NO: ACAAAA 2623 ATP2B4 ADXCRAD_BQ223439_s_at CCCCATTCAGGTCATGGTAGAATCTACTCCTTGGTAGTCACTTGTCATTTTTANAGAAAT SEQ ID GATGACAATCCTCTTGGCATCACCCCACCCCACATTCTCCCCGATGGTCCTCTCCTGAAT NO: TCTGGATTTTGTCCTACAAGTCTGTGCCATTTATAA 2627 RRAS2 ADXCRAD_CX783318_s_at AACGGCCAGGAAAAGCCCTCATCTTCTCTTTCTCTCCTCAGTTTACATCTTGTTGGTACC SEQ ID TTTCTAGCCTTAGACAAATGATCACCATGTTAGCCTTAGACCAAGAAGCTGGCTAGTCCT NO: TTCTGTGAAGCTAATACAATGGTCATTTCCAGACAAATTTAAAGGAAACACTAAGGCTGC 2639 TTCAAAGATTATCTGATTCCTTTAAAATATATGTCTATATACACAGACATGCTCTTTTTT TAAGTGCTTACATTTTAATAGAGATGAATCAGTTTTGGAATCTAAGCTGTTTGCC CCND1 ADXCRAD_BQ436873_at AAAAATAGTATTTGCATAACCCTGAACGGTGGGGGAAGAGGGGTGTGCTACANATGATAG SEQ ID AGGGATTTTATACCCCAATTATCAACTCCGTTTTTATATTAATG NO: 2640 PTRF ADXCRAD_BI869786_at GGTGTATCCCGGTATTTGGTGTACAAACAGTTGGTCCCATTATTGAAGTCGCACTTTTAT SEQ ID ATACACACATAGTACGATGTCAACCGTTGTTTTACACACCGCTGGAGATCGGGCAAAACA NO: CGCGAACAGACACGGGGCGAAACCTCGGGCAGAAGCGCACCCCAACATCACAGAGGGGGC 2642 TGAACACCAAGGCGCAAAACTCAACCATAAAGCGAGATTAAAGACAGACGAGGGCACAAA GTAAAACCTGTACACGCGCCAACACGGGACACAA WNT5A ADXCRAD_BU627790_at AGTGGGCTGAATATTCCTTAGGGACTCAATTAATAAGTACTGTCATTTCTAATAGGCATG SEQ ID GGTTTCCATTCTGCAGAATGAACTAAGAAAAGAGAAACATTGCTGATGCTTCTGAGTTTT NO: GAATATCTC 2645 WNT5A ADXCRAD_BU627790_x_at GATATGAAAGCCAACCTGCCTAAGGGGGGTATGAAAGATGTGTATCTTTCCAAACTTTTA SEQ ID AAACAACGTAAGTCTGAGATAAGAACATATTTGATGGCACTGTTTGGAAAGAGGTGTCCT NO: TATTAAAAAAAAAAAAAAAAAAAAAGCTATCTATGTAGTGGGCTGAATATTCCTTAGGGA 2646 CTCAATTAATAAGTACTGTCATTTCTAATAGGCATGGGTTTCCATTCTGCAGAATGAACT AAGAAAAGAGAAACATTGCTGATGCTTCTGAGTTTTGAATAT KIF2C ADXCRAD_CV804054_at GCAGCCTGAAAAGCAGGCTAGCAGACAAATAAACAGCAAGAAAACGGCCCCATTGACGAC SEQ ID TGGCAATAAAAAT NO: 2651 KIF2C ADXCRAD_CV804054_s_at CTGGAGACCTTTGTGAACAAAGCGGAATCTGCTCTGGCCCAGCAAGCCAAGCATTTCTCA SEQ ID GCCCTGCGAGATGTCATCAAGGC NO: 2652 COL4A2 ADXCRAD_BM546367_at CCTGGAAGGCCACAAGCTTAACCACTTTCGCACAAACCCCATGTTAACCACTGGCNACTT SEQ ID TTCCAATGGCCACAGAACCAACTCACCATTGGTTCA NO: 2656 COL4A2 ADXCRAD_BM546367_x_at TGGAAGGCCACAAGCTTAACCACTTTCGCACAAACCCCATGTTAACCACTGGCNACTTTT SEQ ID CCAATGGCCACAGAACCAACTCACCATTGGTTCA NO: 2657 IL6ST ADXCRAD_BQ887381_at AGGGATTTTTACCACATGAAAGTCATTCCAGTGGACCCTAACCTCCTTATTGGTGGAAGG SEQ ID TTAGTG NO: 2658 IL6ST ADXCRAD_BQ887381_s_at TTTTACTATGGATCAGTCGGCACTCGGGAACAGCAGCAAGGAAAAAAAGCAAATTTCATT SEQ ID CACATGTTC NO: 2659 IL6ST ADXCRAD_BQ887381_x_at TTTTACTATGGATCAGTCGGCACTCGGGAACAGCAGCAAGGAAAAAAAGCAAATTTCATT SEQ ID CACATGTTCTGGGTTCATACCTCTTCTCTACCTAATTGGTCATTTTAAATTTCCAGCCTT NO: ATTCCCTGGATAAGGGATTTTTACCACATGAAAGTCATTCCAGTGGACCCTAACCTCCTT 2660 ATTGGTGGAAGGTTAGTG RRAS2 ADXCRAD_BU929840_at GTATTCCCTGCTAGATATTGATTGTTATTTCAAGTATTAAGTGTAAGCTTTTAATGGATA SEQ ID ATTAGTATAACTGTGGATGGCATCTGATTTTGTTTTTAATTCTGTGGATTGTGTTTAAGC NO: AATTCAATAGTATGTTCCTGATTTTGAGATGCTAAGTGGTATTGCACAGTTGTCACTTTA 2662 TCAAGTGTGTACAACAGTCCCATGAAGTTTATAGAGCATACCCTTGTATAGCTTCAGGTG CTAGA PRNP ADXCRAD_CX762421_at ATAACATTGGTTATCTGGACTATTTTGGACTAGTGCACAGGTGAGCTAAACAATCTAGAC SEQ ID ATCTGAATACTTGCTGGATCTCTGCTCTCACACTAAGTCATACTATGCTACTATAAATCA NO: ACTATAAGAATCATTAGAACGAACTCGCAG 2673 PRNP ADXCRAD_CX762421_s_at CTCTTTGTCCCGGATAGGCTAATCAATACCCTTGGCACTGATGGGCACTGGAAAACATAG SEQ ID AGTAGACCTGAGATGCTGGTCAAGCCCCCTTTGATTGAGTTCATCATGAGCCGTTGCTAA NO: TGCCAGGCCAGTAAAAGTATAACA 2674 SPTBN1 ADXCRAD_AW028717_at CTTGCCTTAAAGCAGCATACTTATTTTTTGTTTATTTATTGTGAGCTTTNTACTTTATTA SEQ ID AGATTNTACAGCGAAACCCTTACATGAGTAATTGAAATG NO: 2675 SPTBN1 ADXCRAD_AW028717_s_at TGAAGTTCACTACCATTTGTCAAGAATCACCCTTTCCAAATCCTCTGGGTTTTGACTTTT SEQ ID TGGCTTCCACTTCACCCAAAATGTTAAAATTTTTACTTAATTCATAGCCTTCCTTGGTTT NO: CATATTTGTTTGCATTTAATTCATGTTTGAGTCTCTTAACTGATGGATGCCCACTTGCCT 2676 TAAAGCAG SYNJ2 ADXCRAD_BF875753_at TCATAGGGAGAAGAGCGCTGCTTGTGGCAGGGTGGCGTGTGGCTGTCATTAAAGTGCGTT SEQ ID CCTTTAATGAGCGCTCAGGGCTCCCAGGGGCCTGCTGCTATGCCATGGGGTGGGGCTGCC NO: AGCAGGGCAGGGGGTTGATCCCATCACATCTCCCCAGACACATCCTCAGGAAACCACCTC 2677 AAAACCACCTAAGAACAAAGGAAGTTATCACACTGGGGACAGGGACACGGGTCAGAGTTC AGCTACGCTGGAATGGAA SYNJ2 ADXCRAD_BF875753_x_at TTTCCTCACCACACTTCATAGGGAGAAGAGCGCTGCTTGTGGCAGGGTGGCGTGTGGCTG SEQ ID TCATTAAAGTGCGTTCCTTTAATGAGCGCTCAGGGCTCCCAGGGGCCTGCTGCTATGCCA NO: TGGGGTGGGGCTGCCAGCAGGGCAGGGGGTTGATCCCATCACATCTCCCCAGACACATCC 2678 TCAGGAAACCACCTCAAAACCACCTAAGAACAAAGGAAGTTATCACACTGGGGACAGGGA CACGGGTCAGAGTTCAGCTACGCTGGAATGGAA MAP7D1 ADXCRAD_BU178034_x_at GTAAATAGCTTGTGCTCAGACTCCTCTGCGTGGAGAAGGTGGGTGCANGAGGCAGACCCT SEQ ID CCCCCCAAAGCCCCCTGGGGAGATCTTCCTCTCTCTATTTAACTGTAACTGAGGGGGGAT NO: CCCCAGGTCTGGGGGATGGGGGACAACCTTGGGGCCACAGGATACTGGGTTTGCTTCAGG 2681 GGGTACCCATGGCCCCCCTGCCCTCGGCCTGGGAATCAGTGGNTACTGGCATCTGAATTA AAATGTTCTTCCCCGA LRP12 ADXCRAD_BP262656_s_at AAACGAAACGAGTGATGATGAGGCTTTGTTACTTTGTTAGGTACGAATCACATAAGGGAG SEQ ID ATTGTATACAAGTTGGAGCAATATCCATTTATT NO: 2687 PHACTR2 ADXCRAD_AV721683_at TATTAGAAAAGTTGAATCGCATGACTACATTTATACAGGGGAAATTCAAGCATTTGTGTG SEQ ID TGAATTAAATGCTTCGTTAATAGGATAAGCAGGTGATTCATTTGGAACTTATGGGATGCA NO: GCATAACCAGGTGAAATCTAATGGTGATTTATTTCCAAAGACCACCAGGTTTGTTCAAGT 2690 GCATTGCTAGTCTGTGTTTGTGTTTAACCCATGCAACAATCCTCATGACAGTAACAAGGA TTATGACCAAT CORO1C ADXCRAD_BU181829_at GGTATTTGCCCTGGGGGGATCCTGATACCCTGGGCTG SEQ ID NO: 2692 PHACTR2 ADXCRAD_CN369598_at AAAAGGTCCAGTTTTACAGCCTGCAATTAATTCAGGGCTGCGTTGGCATTAAAAAAGAAA SEQ ID ATATATATATATATATATATATATATATATATATATATGTATATTATATATACAGTAGCT NO: TACACTTAAAAGAGGAAAAATTTGCATTAACATTGCATATTCTGATATGTACCATATTAA 2693 CACATAACAGGCATTTTATTTATGCTTCATAGAATCAGACAGACACAACTTTCAAAA JUN ADXCRAD_NM_002228_s_at CAGCCCACTGAGAAGTCAAACATTTCAAAGTTTGGATTGTATCAAGTGGCATGTGCTGTG SEQ ID ACCATTTATAATGTTAGTAGAAATTTTACAATAGGTGCTTATTCTCAAAGCAGGAATTGG NO: TGGCAGATTTTACAAAAGATGTATCCTTCCAATTTGGAATCTTCTCTTTGACAATTCCTA 2694 GATAAAAAGATGGCCTTTGCTTATGAATATTTATAACAGCATTCTTGTCACAATAAATGT LOXL2 ADXCRAD_BI825165_at GGAATAACAAGAAAGATCTATGAACAGAACACAAACAAACACAGCAAGCTAACAAAA SEQ ID NO: 2695 CASK ADXCRAD_CX786970_at TGGTCCCTAGAGACTACCTAGTTGTAGTGTGACCTACATTTATAATTATTGTCATGTCCG SEQ ID AATAGATAGGAGGAGAAAAACAATTACACACTAATTTAAAGAGACAGTATCTTTTTTAAT NO: CAGTTCTCCTAAACTTTAATAAAATGTATCTTTAAATGTATGTATTATTCAATCCTTTGG 2696 AATGTTATATTTTTGGAAATCATAGCTTTTTA MGAT1 ADXCRAD_BP302925_at AAAATCAGTGCCCTCCCTGTTGCTCTAGGAGGCTCCTGCTGGCTTGGTAGAAGACAGAAT SEQ ID TCGATCTGCCTGTCCCTTTTTCCCCTGGGGTTTGACACACAGGCTCCTCTCAGCATGAGG NO: TGGAGCAGTGACCAGGTGGAGCAGTGACCAGGACGCCTCTGGCCCAGTGCTGCCCAGCCT 2697 CCCCGCCCGCTCCCAGGCGCCCCATGTCCTCACAGGCCAGGACGCCATGGCAGGATGGAG AGGACTTGGTGGATTTTT MGAT1 ADXCRAD_BP302925_x_at AAAATCAGTGCCCTCCCTGTTGCTCTAGGAGGCTCCTGCTGGCTTGGTAGAAGACAGAAT SEQ ID TCGATCTGCCTGTCCCTTTTTCCCCTGGGGTTTGACACACAGGCTCCTCTCAGCATGAGG NO: TGGAGCAGTGACCAGGTGGAGCAGTGACCAGGACGCCTCTGGCCCAGTGCTGCCCAGCCT 2698 CCCCGCCCGCTCCCAGGCGCCCCATGTCCTCACAGGCCAGGACGCCATGGCAGGATGGAG AGGACTTGGTGGATTTTTGTTTCTTGCCTGACCTCAGTTTCATGAAAGAA AMOTL2 ADXCRAD_BU580920_at GTGTCTGTATGTTTAAGTTATCGTAAATATTTAAAATGTAAACATGGCTGTTTTGTTATG SEQ ID CCACCCTGTACCAGGATTG NO: 2699 AMOTL2 ADXCRAD_BU580920_x_at TTAAAGTATTTTTTGTGCTGTGAACATTTTCTGCCAAAGACCATGATGTGTGTCTGTATG SEQ ID TTTAAGTTATCGTAAATATTTAAAATGTAAACATGGCTGTTTTGTTATGCCACCCTGTAC NO: CAGGATTGCTG 2700 HK1 ADXCRAD_BG675101_at AAAAATAGAGGCTCACCCCAGTCTCGTCGGCAACAGGGGGGCCCCCAAAGAGGAGGGCAT SEQ ID ATATAGACGCCACGCGAGCGGCGGCTATAAACCACACGCTGCAGGGGGAAACACGCCGCA NO: CCTAGCGCCCTGGGGAAGACGCCCATACATGAGGGCGGGGCCACACGTGGGACACACACT 2702 CACCGAAAATTAGCGCCGGGGGAACAACAATGCGGGGTAGCGGGCAACACAGCGGAGGGC GCGGGAAGAAATGCCACGGGCATATGAGCCATAACCG PYGL ADXCRAD_BQ933107_at TTGGTTTTGTAAGCTAACAAATCTATAATAATTTGAGTATCCCCGGGGAATG SEQ ID NO: 2703 PDLIM7 ADXCRAD_CN298673_at ATCAACCTGGAAGGAAAGACCTTCTACTCCAAGAAGGACAGGCCTCTCTGCAAGAGCCAT SEQ ID GCCTTCTCTCATGTGTGAGCCCCTTCTGCCCACAGCTGCCGCGGTGGCCCCTAGCCTGAG NO: GGGCCTGGAGTCGTGGCCCTGCATTTCTGGGTAGGGCTGGCAATGGTTGCCTTA 2706 CDH11 ADXCRAD_CX866982_s_at GGGTCCCTGAGCTCCCTAGAGTCGGCCACCACAGATTCAGACTTGGACTATGATTATCTA SEQ ID CAGAACTGGGGACCTCGTTTTAAGAAACTAGCAGATTTGTATGGTTCCAAAGACACTTTT NO: GATGACGATTCTTAACAATAACGATACAAATTTGGCCTTAAGAACTGTGTCTGGCGTTCT 2709 CAAGAATCTAGAA TUBB3 ADXCRAD_CN295380_at GGGCCCCAAGTGAAGCTGCTCGCAGCTGGAGTGAGAGGCAGGTGGCGGCCGGGGCCGAAG SEQ ID CCAGCAGTGTCTAAACCCCCGGAGCCATCTTGCTGCCGACACCCTGCTTTCCCCTCGCCC NO: TAGGGCTCCCTTGCCGCCCTCCTGCAGTATTTATGGCCTCGTCCTCCCCACCTAGGCCAC 2710 GTGTGAGCTGCTCCTGTCTCTGTCTTATTGCAGCTCCAGGCCTGACGTTTTACGGTTTTG TTTTTTACTGGTTTGTGTTTATATTTTCGGGGATACTTAATAAATCTATTGCTGTCAGA NT5E ADXCRAD_BG611920_at TAAAAATTGGACAGATTAGCCCAAAAAAAGACACAATCACAACAAACAAAACAAAAACTA SEQ ID TTGTTGGCGGCACTGTGCGCCCCAAAGAAACTCTGTAAAACACCTAGCGGTTAGGCACAG NO: CGGCCCCATAGGAAAGCGAACATGTGCAAACATGTCCCCAGAAAAACCCGGAACAAAAAA 2714 ACGGCGCGGAAACGCACCCAAAAAACACGCCCGGGGAACCGCGGTTTTGGACAAACCAGA GACATCACAACAAAA LIF ADXCRAD_BU175373_at GCACATGGGCCTTGGGGTGACAAATTCCCTCCTTTGGATGAATGTACCCCTGGGGGGGAT SEQ ID GGTTTCATACTGGAAGGATTAATTTTTTATTTCATTCCCATGGGCCATAATTCTAAAAAT NO: 2715 LIF ADXCRAD_BU175373_x_at TTTCCACTGAAAAGCACATGGGCCTTGGGGTGACAAATTCCCTCCTTTGGATGAATGTAC SEQ ID CCCTGGGGGGGATGGTTTCATACTGGAAGGATTAATTTTTTATTTCATTCCCATGGGCCA NO: TAATTCTAAAAAT 2716 JUN ADXCRAD_AJ712294_s_at AGGAAGCGCATGAGGAACCGCATCGCTGCCTCCAAGTGCCGAAAAAGGAAGCTGGAGAGA SEQ ID ATCGCCCGGCTGGAGGAAAAAGTGAAAACCTTGAAAGCTCAGAACTCGGAGCTGGCGTCC NO: ACGGCCAACATGCTCAGGGAACAGGTGGCACAGCTTAAACAGAAAGTCATGAACCACGTT 2719 AACAGTGGGTGCCAACTCATGCTAACGCAGCAGTTGCAAACATTTTGA TGFBR2 ADXCRAD_BI334991_at TGTACTCATGTTTTACCAACTCCGGAATGTGAATGCTATAATACTCTTTTTATATCACAA SEQ ID AGGTCCTCAAGCACTTTATTTCTATTCTAATGCATTGGTGTGTCCTTTTACCATTAACTC NO: ACAACTGTTTCCTCCAGACTGGATTACAGCAAATACTCCTGGGTCAAAACAAA 2720 LAMB3 ADXCRAD_CB122452_s_at TACTATGCCACCTGCAAGTGATGCTACAGCTTCCAGCCCGTTGCCCCACTCATCTGCCGC SEQ ID CTTTGCTTTTGGTTGGGGGCAGATTGGGTTGGAATGCTTTCCATCTCCAGGAGACTTTCA NO: TGTAGCCTAAAGTACAGCCTGGACCACCCCTGGTGTGTAGCTAGTAAGATTACCCTGAGC 2721 TGCAGCTGAGCCTGAGCCAATGGGACAGTTACACTTGACAGACAAAGATGGTGGAGATTG GCATGCCATTGAAACTAAGAGCTCTCAAGTCAAGGAA YWHAZ ADXCRAD_CX870884_at TCTATTATGAGATTCTGAACTCCCCAGAGAAAGCCTGCTCTCTTGCAAAGACAGCTTTTG SEQ ID ATGAAGCCATTGCTGAACTTGATACATTAAGTGAAGAGTCATACAAAGACAGCACGCTAA NO: TAATGCAATTACTGAGAGACAACTTGACATTGTGGACATCGGATACCCAAGGAGACGAAG 2722 CTGAAGCAGGAGAAGGAGGGGAAAATTAACCGGCCTTCCAACTTTTGTCTGCCTCATTCT AAAATTTACACAGTAGACCATTTGTCATCCATGCTGTCCCACAAATAGTTTT GATA6 ADXCRAD_BX384651_s_at AAATTGCCTTTCTCTATTTGTTAAGAATTTTTATACAAGAACACCAATATACCCCCTTTA SEQ ID TTTTACTGTGGAATATGTGCTGGAAAAATTGCAACAACACTTTACTACCTAACGGATAGC NO: ATTTGTAAATACTCTAGGTATCTGTAAACACTCTGATGAAGTCTGTATAGTGTGACTAAC 2725 CCACAGGCAGGTTGGTTTACATTAATTTTTTTTTTTGAATGGGATGTCCTATGGAAACCT ATTTCACCAGAGTTT NFIB ADXCRAD_BQ672667_at AGTTCAGGCCTCTGGGATCAACCCCAGACTGGGCCAGAATGTTAGTGAAGGTTTTATTGT SEQ ID GCCCGGTTGGAGGATAACGTTCTTTGGGTACTTTTTGTGGGTTGCAAATGAACTCAATTG NO: CCACAAGTTTTAAACTGGTGTAAATCAAGCTTGACTTAATGTGATTGTTACTGTTATATC 2727 CAGCCTATACTGCTAGCAGCTGCTCATACTGCAGTCAATTACTGGAAGCGGATATATTTC CTATGCAAAA ZFP36L1 ADXCRAD_CX782083_at TCCCGGAGCCTCTGCCCATGGCGGGGTGGAGACCCGGAACCAGCAGCCCCCTCCACTGGC SEQ ID GACACAACTGCACCTTCCCTCATTTCAGTCTCCCGCACACTTATTCCTCCTCCCCTCTTC NO: CCGGTGGCACCTCTCCACCT 2731 ZFP36L1 ADXCRAD_CX782083_s_at TTCTTCCCGATCTGAACCCCTGTTGACTAATCTTGCCTGGGTTTGTGTAGGTCTGCAGGA SEQ ID AGGA NO: 2732 COL4A1 ADXCRAD_CX761316_s_at AGCCGCTGCCAAGTCTGTATGAGAAGAACATAATGAAGCCTGACTCAGCTAATGTCACAA SEQ ID CATGGTGCTACTTCTTCTTCTTTTTGTTAACAGCAACGAACCCTAGAAATATATCCTGTG NO: TACCTCACTGTCCAATATGAAAACCGTAAAGTGCCTTATAGGAATTTGCGTAACTAACAC 2733 ACCCTGCTTCATTGACCTCTACTTGCTGAAGGAGAAAAAGACAGCGATAAGCTTTTCATA GTGGCATACCAAATGGCACTTTTGA LDLR ADXCRAD_BX113541_x_at AACTCAGCTGGACTTTTCTTGCTTTAATAACAGCTTTATTGAGATACAATTCACATATCA SEQ ID CGAAATTCTTTTTAAAAATTTTACAGTTCAGGCCGGGCGCGGTGGCTCATGCCTGTAATC NO: CCAACACTTTGGGAGGCTGAGGCTGGCGGGTCACCTGANGTCAGGAGTTCGAGACCAGCT 2735 TGGCCAGCATGGCAAAATCCCGTCTCCACTA ACTN1 ADXCRAD_BM714793_at AAGAGAATTTATGTGGCTTCTCATTTTTAAATCCCCTCAGAGGTGTGACTAGTCTCTTTA SEQ ID TCAGCACACACTTAAAAAATTTTTAATATTGTCTATTAAAAATAGGACAAACTTGGAGAG NO: TATGGACAACTTTGATATTGCTTGGCACAGATGGTATTAAAAAA 2737 RYBP ADXCRAD_BU151619_at AAGGTTATCAACCACACATCCAGTCCTGACATGGAGCTTTTCAGTGTTTGGAGACATTTC SEQ ID TCAATCCCCTGCTGTGGTAGGAACTCCAGTGGTGAACGGCTTGCGCGCCTGCAGCCAGAG NO: TTGCAGGGAAAGCTCGTACTTACTGCGAGCAGCATGTAATCTTTTTTCTTCCTGGACATA 2738 AAGATAGCTTGAGTAAACTGTTCTATTTCATTCTCTTCACTCTTTTTACTGTCTTGCAAA AA TRAM2 ADXCRAD_BM700086_s_at AGGCTGTGTCATTGGCAGGGCTTCACATGCAGGAGGCCTCTCTCAGGTGAGTCCAGGTTA SEQ ID AACTGTTGAGTTGTGGCTTCAACAGATATGTATGGCATGCTGGGATGTGCCAGGTGCCTG NO: CGTTGTGCCAGTTGCTGGAGAGGTAGTGTGAGCAGAGCAGCTGAAATCTTGCCATCAAGC 2739 AACCCTCATTCTCATGCCTGTAGGTTTCCATTGCTCTGTCCCAGGACACTTGCGTGCCAG AGACGCCACAACTTCATGTCCCTGTCTCTTGCAA CDC14B ADXCRAD_AW021718_at AGACTTTTATCTAACCTGCACTCATGTACAGATTATTAAAAGTTTTAAAATGTAACTGAT SEQ ID CAGTATTGATCAATCATTGTCTTGATT NO: 2742 SEC61A1 ADXCRAD_BQ711397_at TCCTGGCACTGGCAAAAAGAACTGTGAAAGTGAAATTTTATTCAGCCGACTGCCCAAAAA SEQ ID GTGGGAAATGGGAATAGGATTGTCCCCCAGTGTCCATGGTAACTTTTGTTTTAACCTTTG NO: CACCTTCTCAGTGGCTGTATGGCGGCTGCAACCGGCCTCACCTGTTTTCCCCCCAAAGGG 2746 GATTTCTCCACCTCTTGGTTGGAAACACCAA CRIM1 ADXCRAD_C16716_s_at CTTCTAGCCGTCAAACTCTGATCGACTTACACTTAAGACTGTGTCTTTGGTAGCCTACCC SEQ ID TATTCCACTTTTATTACAAAGGCAGCTCTTAAGACATAAATCCATCTCTTCAGGCTCGAA NO: CTGCAAAACACACGTCGAGAGGTGACAATGTTGGGACTGTCAAAAAGAACTTAAAGAGTG 2751 GGATAACCAGCCGGGC CASK ADXCRAD_BP254716_at TCCTCAGGAGCAGTCTCACAGGTGCTGGACAGCCTGGAAGAGATTCATGCGCTTACAGAC SEQ ID TGCAGTGAAAAGGACCTGGATTTTCTACACAGTGTTTTCCAGGATCAGCATCTTCACACA NO: CTACTAGATCTGTATGACAAAATTAACACAAAGTCTTCACCACAAATCAGGAATCCTCCA 2753 AGCGATGCAGTACAGAGAGCCAAAGAGGTATTGGAAGAAATTTCATGTTACCCTGAGAAT ADAM9 ADXCRAD_NM_001005845_at TTTGTGTCTCCTAGTAGCTTCCTACTCAACTATTTATAATCTCATTAATTAAAAAGTTAT SEQ ID AATTTTAGATAAAAATTCTAGTCAAATTTTTACAGATATTATCTCACTAATTTTCAGACT NO: TTTGCCAAAGTGTGCACAATGGCTTTTTGTTAATAAAGAACAGATTAGTTTTGAAGAAGG 2758 CA ADAM9 ADXCRAD_NM_001005845_x_at TACTTGAAATTCTCTTTTGTGTCTCCTAGTAGCTTCCTACTCAACTATTTATAATCTCAT SEQ ID TAATTAAAAAGTTATAATTTTAGATAAAAATTCTAGTCAAATTTTTACAGATATTATCTC NO: ACTAATTTTCAGACTTTTGCCAAAGTGTGCACAATGGCTTTTTGTTAATAAAGAACAGAT 2759 TAGTTTTGAAGAAGGCAAAAATTTCAGTTTTCTGAAGACAGCATGTTAT PHACTR2 ADXCRAD_NM_014721_at TAACCACAAGACCTCTCTATAATGGTAAATGTAAGACATCACCATTTTATCACTCAAAGT SEQ ID ATGTTATTGAAAGTTTCTATTTGGTTGATAAAAGGAACAATTTTTTCCCACTTTTGATGC NO: CTGTGATGCAATTTTTTATTGCCTACAATGAGATACACTTAGTACAAAAAATGAAAATCT 2761 GGTATTTCAAAATTGCATTTCTTGTATAATAGGTCAGATTTATTAACTACTCATACTTTT TCTTTACACTAATCGATACATTTA PHACTR2 ADXCRAD_NM_014721_x_at TAACCACAAGACCTCTCTATAATGGTAAATGTAAGACATCACCATTTTATCACTCAAAGT SEQ ID ATGTTATTGAAAGTTTCTATTTGGTTGATAAAAGGAACAATTTTTTCCCACTTTTGATGC NO: CTGTGATGCAATTTTTTATTGCCTACAATGAGATACACTTAGTACAAAAAATGAAAATCT 2762 GGTATTTCAAAATTGCATTTCTTGTATAATAGGTCAGATTTATTAACTACTCATACTTTT TCTTTACACTAATCG EGFR ADXCRAD_NM_201283_at ATCACAGGTTTGAGCTGAATTATCACATGAATATAAATGGGAAATCAGTGTTTTAGAGAG SEQ ID AGAACTTTTCGACATATTTCCTG NO: 2765 EGFR ADXCRAD_NM_201283_s_at AATGCTACGAATATTAAACACTTCAAAAACTGCACCTCCATCAGTGGCGATCTCCACATC SEQ ID CTGCCGGTGGCATTTAGGGGTGACTCCTTCACACATACTCCTCCTCTGGATCCACAGGAA NO: CTGGATATTCTGAAAACCGTAAAGGAAATCACAG 2766 ULK2 ADXCRAD_NM_014683_at AAGTGATTGGCCTAAAGTCAGGAACTAGGCAAGTGGTCAAGCCATGCTTTGTGACTTTCA SEQ ID AGTTAATTCTTCTTGTTCTTGTATATTAAAGGTCTTGGGGTAGATGGTGTGTGTGAAACA NO: GTGAAGTCTCAACAGCAGAAAAGAACAAAATGTAAATTCATGAATAATGGTTCTGGTTAT 2771 ACTTCCATTATCAAGGCTAATTAAGAGATTTTGCCTTGAGTATAGCAATAATAAACAAAT GCTTTATGTTTCCCT NT5E ADXCRAD_BC015940_at TTCTTTACACAGGTAATTGTTTCAAAAGGATTGCATGGGCCAGGATGTCCAGATAAGCAC SEQ ID TGTGTCTCTTTTGCCTTTGTAACTGTTATTACTCTTTTTACTGCTATTTAATATGTAATG NO: TATATTATATGATCTATAATATATATGTAATATACATTAAATGGGAACATGTGCAAATCT 2778 TACAAAA LPP ADXCRAD_AL833171_at TTGGCCTATTCTGGACTGCAAATAGCATTGCCAAGCACTTCCCTTAAATAACTTCTCTTT SEQ ID TTTGCAGGACTATCCTCTCAGCCCTGCCAAAACCCCATCACCTACTCTTTCTTTACTACT NO: TTGCCTATTTAATGCTGGAATTTTTATTTAAACTGTAGCTGATTTACTGAAGGTAATTAA 2784 GTGCTTTCATGCTGTAGATCTCCTGCTAGACTACAGGCTGTACTTGGGAGTGAGAGTGAA CCAAATGTAA CRIM1 ADXCRAD_BC016339_s_at AAGAATCTTCACTTGGGTGCAGCCTGTTATCTCTGTAATCTACCTGGAGGTGACCCATAT SEQ ID CTAGGAGAAAAAAAATTATAAGCATTTATTACCTAAACCAGAATTGTTAAGGATTATTTT NO: AATGACATTGCAAATAGAGATCAGCAACTTGGTTTTATTGCTTCCCAGTTTTTTGAGGCT 2786 AAAAATGTGATTAAAATCTAATGTTGATCCAAAGAGCTCTTAGTAGAGAGCAGAGCGCTT A ZNF264 ADXCRAD_AL832061_x_at AGGCATGATGGCAGGCACCTCTAATCCCAGCTACTCAGGAAGCTGAGGCATGAGAATCGC SEQ ID TTGAACCCAGGAGGTGGAGGTTGCAGTGAGCTGACAGCGTGCCACTCTACTCCAGCCTTG NO: GTGATAGAGTGAGACTCCA 2787 LDLR ADXCRAD_BC021296_s_at GTCCCTGCTGTTTAGATGTCGTGTTGTAGGAGCCTGTTGCTCAGCCTCCCGAGTAGCTGG SEQ ID GATTACAGGTGCCTGCCACCACACCCAGCTAACGTCTCTACTAAAAATACAAAAAATTAG NO: CCGGGCGTGGTGGCGGGCACCTGTAGTCCCAGCTACTCGGGAGGCCGAGGCAGGAGAATG 2788 GTGTGAACCCGGGAGGCGGAGCTTGCCGTCAGCCAAGATAGCGCCACTGCATTCCCGCAG CGAAAGAGCGAGAC MDFIC ADXCRAD_BC040713_at TTCAGCAGATCCAGGACTGCCGCAGCTCTCTGAACAAGCGTGCACTTACTCCATTTCATC SEQ ID TT NO: 2789 MDFIC ADXCRAD_BC040713_s_at CTGTTTCTTGTTGGCTCCTCTACCACCCGGTTGATAATTCAGGTTTCTGTGACCAGTAGC SEQ ID TTTGGAATGGCTTATGCTTGTTTTCA NO: 2790 MDFIC ADXCRAD_BC040713_x_at ACAGCCCAGGGTCTCTTCAGCAGATCCAGGACTGCCGCAGCTCTCTGAACAAGCGTGCAC SEQ ID TTACTCCATTTCATCTTTCTGTTTCTTGTTGGCTCCTCTACCACCCGGTTGATAATTCAG NO: GTTTCTGTGACCAGTAGCTTTGGAATGGCTTATGCTTGTTTTCAAT 2791 PLAUR ADXCRAD_AF087989_at TTAGCTGGGCATCAGGCATCGTGCACAATCCTGTACTCCCGGCTACTTGTGAGGCCGAGG SEQ ID TAGGAGGATTGTTTGAGCCTGGGAGGTCAAGGCTGCAGTAAGCTATGATTGCACCACTGC NO: ATCCTGGTTGACAGAGCAAGATTCTGTAAGTAAGTAAATAAAATAAATAAATAAATAAAT 2792 AAATATAGCAAGCTGGTTTGGAGTGAGGAATATTAA PLAUR ADXCRAD_AF087989_x_at TTAGCTGGGCATCAGGCATCGTGCACAATCCTGTACTCCCGGCTACTTGTGAGGCCGAGG SEQ ID TAGGAGGATTGTTTGAGCCTGGGAGGTCAAGGCTGCAGTAAGCTATGATTGCACCACTGC NO: ATCCTGGTTGACAGAGCAAGATTCTGTAAGTAAGTAAATAAAATAAATAAATAAATAAAT 2793 AAATATAGCAAGCTGGTTTGGAGTGAGGAATAT CAST ADXCRAD_AK026822_at TGGCCCACACATCAAAGTCCTCGAGTTTAGGACTGAAGAAAAGTCTGCTTTTGTAGAAAA SEQ ID TGTGTATGCTTCATGTTCTCTTTTACCAGACAATGAGAATAACTCATACTGATTCCTCAT NO: TTTTCCTTGACTTCCAGGAATGTCTGTGATAAATTCAGGGGACAATTGCGAGAATTATCC 2794 TCAGCCATAAGTCCCTCACATGGTTATCACCTGTCCATTATGTATCTTTTTGTCCTTCAT TTTAACATTTCTTTTATACATGGATCTTA ZNF264 ADXCRAD_AL833343_x_at TTGAAGTGAACTGAGATCTCGCCACTGCACTCCAGCCTGGGTAACAGAGCTACTCTGTCT SEQ ID CAACAACAACAACA NO: 2796 WNT5A ADXCRAD_NM_003392_s_at CAGATTGTTCCTTTTTAGTGACTCATGTTTATGAAGAGAGTTGAGTTTAACAATCCTAGC SEQ ID TTTTAAAAGAAACTATTTAATGTAAAATATTCTACATGTCATTCAGATATTATGTATATC NO: TTCTAGCCTTTATTCTGTACTTTTAATGTACATATTTCTGTCTTGCGTGATTTGTATATT 2804 TCACTGGTT SEPT7 ADXCRAD_AI831470_at ATTAAGTTTATCCTTTTCTCCATCTTTTCTTTCTTGCCACCTAATGAAGGAAATGTCTCC SEQ ID AAGGTCTTTTTGACTAATAGAAACTAAATGTATAACTCGACATCTAGAAGGGTTTCAAGA NO: TAGTAGATATGTCTGCTGGGATGTTTTGTCATTACCCTGCCCAATGTTGCGACGCTAGGA 2805 GTTTCCTTGACACTACATTATAAATAAGGCCCAACCTGTTAGCAAAAATATCACATTCCC TAATTTTCTCTCCTTTAACTGTGTGTAATTTATCCAGGCATGTCTTTAGTTCAG BCL6 ADXCRAD_AW264036_at AGGATCGCTGCCTGCGCTGCGCTGGCCGCCGGGGATTCACCCGGGGAGGCGGGGCCGCTG SEQ ID GGGAAGGCTCGCGGGGAATACAGCACACTTTCCCCTAAATCCCTCGTCCGCGCCGAGTGC NO: AGGGCTCTCAGAGTTCACCTAGTCCCACCTCTCACCCACAACAGTTTATAAATGGGGAAG 2806 GTCAGACAAGTTAGTAGCAGAGCTGGGTCTAGAACCCAGGAGTTCGAATACAATCCGAGG CTCATATCGAGACTTTAAGTTGTCCGATTCCGAAGTTTATTTGCT AURKA ADXCRAD_NM_003158_at GTTAAGGCACACCTGCTGAGTAAAACAAATATTTCTTGTGTAGCGTTCTTAGGAATCTGG SEQ ID TGTCTGTCCGGCCCCGGTAGGCCTGTTGGGTTTCTAGTCCTCCTTACCATCATCTCCATA NO: TGAGAGTGTGAAAATAGGAACACGTGCTCTACCTCCATTTAGGGATTTGCTTGGGATACA 2810 GAAGAGGCCATGTGTCTCAGAGCTGTTAAGGGCTTATTTTTTTAAAACATTGGAGTCATA GCATGTGTGTAAACTT EGFR ADXCRAD_AA678124_at AGCTGGACGCCTCTCTGACAATTGTGGCTCTGGTGGTGAACCCCTCGGTGTCTCTTCTGC SEQ ID ACCTCTCAAGGCTGCAAAGTGCCAAATACTCTTTTCCAACCAGCTCCCGAATTCCCCCCT NO: CCATCTGGGACTGCATGTCCTGCTTAGCGATTTCAAGCAATGATTTCACCTTTTCATAGA 2813 CAAGGACATTGTCTCATCAGGGCTTGACCATCACTCTGATTTCCAATGCTGACAGCCAAG TGGAGGTTT NR3C1 ADXCRAD_AI934556_at GATGAATGTGCGCTTTGGAAATGTTTAAATAGATATGAAATGATTAAATAAAATCACAGT SEQ ID CTTGTGCAACATCCATAGCTTACAGTTATTTGGCAACTATGAAACCACAGTTACTAATGG NO: AATTAAGACTTTNTAAAAAATTGCAAATGTACTTATTTGTATATGAAAGAGGTATTCAGC 2815 TATTAACTCAGTATTTAATAAACATTGATATGTAATTTTTACTTGAAATGGCCTAAGGTT TATAATACCAACTAGTTCATAGAGCTTTTTT ACTN1 ADXCRAD_M95178_at GACGTCAGCCTGTACAGGCTCCCAGGGGTGGCGTCAAATGCTATTGAAATTGCGCTGAAT SEQ ID CGTATGCTTTTTCC NO: 2816 ACTN1 ADXCRAD_M95178_x_at GTGCGCCGTGCCCACAGATGTGAAATGAATGTAATCTAATAGAAGCCTAATCAGCCCACC SEQ ID ATGTTCTCCACTGAAAAATCCTCTTTCTTTGGGGTTTTTCTTTCTTTCTTTTTTGATTTT NO: GCACTGGACGGTGACGTCAGCCTGTACAGGCTCCCAGGGGTGGCGTCAAATGCTATTGAA 2817 ATTGCGCTGAATCGTATGCTTTTTCCTTTTGA EGFR ADXCRAD_AU147861_at AAGGACCCTGAAAAATGACTTCTCATTTCCTGCCTGCAGAAAAGAGAAATATTAGGATAG SEQ ID TGTTGTGTGCAAAAAAATGCAAGCTTGCAATGAGAGATGCAGAGTGTGAGGGAGAGAGGC NO: ACGAAGGGGGTGGAGAAAAAAGACAGAGAATTTGAGGTTGACTCACGGCTTTGAAGGGAA 2818 AACAGGAAGANGAAGAAAGTCTGTCTNCCATGGGTCGGCAACCCACACTTTACACATTTT EGFR ADXCRAD_AU147861_x_at ATGACTTCCTGAAGGACCCTGAAAAATGACTTCTCATTTCCTGCCTGCAGAAAAGAGAAA SEQ ID TATTAGGATAGTGTTGTGTGCAAAAAAATGCAAGCTTGCAATGAGAGATGCAGAGTGTGA NO: GGGAGAGAGGCACGAAGGGGGTGGAGAAAAAAGACAGAGAATTTGAGGTTGACTCACGGC 2819 TTTGAAGGGAAAACAGGAAGANGAAGAAAGTCTGTCTNCCATGGGTCGGCAACCCACACT TTACACATTTTTTCCATGGG AHNAK ADXCRAD_AA523289_at GGCATTTTCACCTTGGGCATCTTCAGGTGCCAGTCTGGGCCATGAACATCCACATCTGGG SEQ ID GCATCAATGTCCACTTTGGGGCCCTTGATGTCAACTTCAGGGNGCTTTAGATCACCTTCC NO: ATCTTAGGCAGAGAAACATCCACATCTCCTTTCACCTTAGGGCCTTTCAGATGCAAATCA 2821 AAGTCAGGCATGGAGATCTTGGGGGGCTTTGATGTTCATCTCTGGCATCTGTATTTAGGG CCTTCAGTTCGCATCTGGACTTCATATTCA RRBP1 ADXCRAD_BE646396_at GAGCAGAGCACATACCTGGTCCGAACTTACAAGTCTCCTTATAGCTTCTCTACAATCTC SEQ ID NO: 2822 RRBP1 ADXCRAD_BE646396_s_at GCAGGTCTGCACAGGGCCCGTGGCTGGGTCTCAGGGTCCTCTGAGGTAGTCAATGTCTCT SEQ ID CATTAAGGAAAAACAGGATGGACAAGATCCCTTGGCTTGAGAGAGAATGCCTCTCTTAAG NO: GCACACGGTCCATGAGGAAGAAATCAGTGAAGTGTCCTCTGCATTAACGTCACTTTCAAA 2823 GAAGCTCCCNGGACATGAGAAAGAGTTCTCTGAGCAGAGCACATA CAPN2 ADXCRAD_AK023851_s_at AGAATGGCAGTTGTCAGTCCTGTCCGTGTAACAGAGGAGTGAAGTGGTGAGGAGGGCAGG SEQ ID TCTAAGGCACTGGCAGCTCTTTTCCATGGATTTTGAACTCTGGAGGAAGGCAGCAACTAA NO: ATAACTGTCTCATTCTGCTATTATGCATTGTATTAGCAAAGTGAAAATATAGTCTATCTG 2826 GTTACAAATAACACTAACTTGCTTAAAACTTTACATATCCTAGGAAATATCTCTACCCCT AGATTGCAATGTAGAGTCAACCCCATCT COL5A2 ADXCRAD_AU144167_at ATTCATGTATATGAGACCTGCTCTACTTCAAAGCTGTAATCTTCTTAGTTGATAAACAAT SEQ ID ATTCTTAAACAAATGCCTTGTAAGGATTCTTAGTAAATGCAGCAGGGCAATTGCTATAGA NO: CCAGTGCATCCTCAGGAGGCCTGGTTCCGGCCATTGCTAACAGGTTTATAAATGGTTTAT 2827 TAAAAAGAGGATAGGTCTCTCACAATGAAATTCGCTAA COL5A2 ADXCRAD_AU144167_x_at ATTCATGTATATGAGACCTGCTCTACTTCAAAGCTGTAATCTTCTTAGTTGATAAACAAT SEQ ID ATTCTTAAACAAATGCCTTGTAAGGATTCTTAGTAAATGCAGCAGGGCAATTGCTATAGA NO: CCAGTGCATCCTCAGGAGGCCTGGTTCCGGCCATTGCTAACAGGTTTATAAATGGTTTAT 2828 TAAAAAGAGGATAGGTCTCTCACAATGAAATTCGCTAA LDLR ADXCRAD_S70123_at GAGGATGAGGTCCACATTTGCCACAACCAGGACGGCTACAGCTACCCCTCGAGACAGATG SEQ ID GTCAGTCTGGAGGATGACGTGGCGTGAACATCTGCCTGGAGTCCCGCCCCTGCCCAGAAC NO: CCTTCCTGAGACCTCGCCGGCCTTGTTTTATTCAAAGACAGAGAAGACCAAAGCATTGCC 2832 TGCCAGAGCTTTGTTTTATATATTTATTCATCTGGGAGGCAGAACAGGCTTCGGACAGTG CCCA PTRF ADXCRAD_AI282511_s_at CTTACTTGGGCAGAAATGTATTACTTATTGTGCCTATTTTCTTT SEQ ID NO: 2833 GALNT2 ADXCRAD_AA604126_at TAGGCTATGGGCTACCCAGATCTGCTGCAAGTGTTACATAGAACATTTCGTGTAAAGCAC SEQ ID ACGGCCCGGTGCCTGGCTCGTAGGAGGCACTCAGTAAACGGCGGTGATATTACAGACACA NO: AAACACGAGGCTGATGTCTCCCTCAC 2836 GALNT2 ADXCRAD_AA604126_s_at TGGGCAGACTTGTCAGGTGGTCTAATGTGAACAAAGCCACAGCCACGGGGAAGAACAACG SEQ ID TGCTTCAGAACCAGATCCAAACCTCAGCCCACCTCTGCCAGGTGCTGGCTTTCAGGCAAG NO: ACTCTCTCTGAAGCTCGATTTGCCCTTTGGTAGGCTATGGGCTACCCAGATCTGCTGCAA 2837 GTGTTACATAGAACATTTCGTGTAAAGCACACGGCCCGGTGCCTGGCTCGTAGGAGGCAC TCAGTAAA WDR1 ADXCRAD_AW770902_at TTCCCAGTCTTTGCACAGAGGTCATAAGAGGCAGAGGTGATGCAGGCAGGGTAAGGAAAC SEQ ID TTATAAGGAACCACCCCAGACCTAAGGAGGTACCAGCACCTGCAGGAAGCCTTCCTTAGA NO: CCCCCGAAGCACAGACTATCCATCCCTTCTCCGTGGGGAACTAATGTCTCTCAAACACAG 2839 TGTACATATGGTTCACTGGAATCCCCTTCTTGGAGCTCTCTCCTTCTGGAATATTAGTTT CTACATGGCCACCATTATAGTCTTTCACTCTACAG ALCAM ADXCRAD_BE502785_at TACTCGCTTTAGAAAAGTGTCCTGAGCAGTGCACTATTCATCTTTCTAATAACATGAAAG SEQ ID TGAAATAGAAAAAAAAAAAAATACATGGGCCACTGGCAAATGCAGGATGCAGACTATTTG NO: GGATGTTTTATGGAAACAGGCATGACTGCAAACACTTGGTTTGCACTTGGTTTGATTCAT 2840 ACAACGATCGAGAAGTGTGGATGGTTTCTGGAAAGTGCCTTCTAAGCTGAAA FNDC3B ADXCRAD_N32832_at GGGCATCTGATACAGGACGTTCTAACCCACAGGGCACTCGCACATGGGTAGGATGTGACT SEQ ID TCTATGTACTGCTCTGCTCTCACAGAGGCCACTCAACAGTGTAACACCAAAGTACATACA NO: TGGCATTCAAAAAGGAAAAGCAAATTATGCTTTCCAAGCGGCAGTGTGTTTTACCTTATC 2846 AAAATCATCTGAGCAGTCAAGATGACCAAGCAGTCCATTT LPP ADXCRAD_AI079544_at GACCTAAAACTGTCTCCAGGACACAAGGCTATTCCAAGCAACATTAAGAGAGAGCTCTGT SEQ ID AGGAAAAGAGGGTCTTGTCAACACAATTCTCAGAATAA NO: 2852 LPP ADXCRAD_AI079544_s_at GGACTCACAAGTCATACCCTACTAAACACCCATCAGATGGACTTGTCTACTTTATTGAGA SEQ ID AACAACAGAAGATAGACCTGCAAGTCCAGCTGTTCATCTACCTCCACCCCACAGCCCAAG NO: CCACATTCCCACCCTTTGTGGATGAAGCTCAGGGATGCAGATCCCATTCCAAGATCC 2853 SEPT7 ADXCRAD_N39126_at CAACAGAAAGATGGACTAAATATAAAGGGGGGAATTCCTGGACCTCCTTTGGGTGGCTAG SEQ ID ACTGGTANGTCATAGGCTAAGCCGGAAGGGTGG NO: 2855 SEPT7 ADXCRAD_N39126_s_at AAACAAGTACAATATCCTGGCATAAAACTATCTTTCAGACAAAATCCACCTGCTGTGTAT SEQ ID TAAAAAATGTAATACTTGAAAACTTCCTGCCTTGGGAGAGACTAAACCCGATTCATAATA NO: CAAA 2856 PDLIM7 ADXCRAD_AI825846_at GCAGGCCCGGATCTTGTTCTGAGCTTCGATGTGTGTGAGGCTACCCGCATTCTCGCCATC SEQ ID GATGCTCAGCACCCAGTCACCCACGGACACTCCGGCCTGCGCCGCTTTGCCCCCAGGAGT NO: GAGCCGGGAAATGGAGAGGGGCACATTGAAGTCCTTGCCCCCTTGCAGCCGGAAGCCCCA 2857 AGGTGCTGGCCCCTCCAGCACTACTTTGAAGGAATCCATGA SERPINH1 ADXCRAD_NM_004353_at GAGCCTTTGTTGCTAATCAAATCCGGGACTTGTTTGTACG SEQ ID NO: 2858 WDR1 ADXCRAD_AF274954_at GTAAGTTTAAAGCACCTGATTGGGAGTGTTTTGCGTGTTCGGAATCACTTGTAATGTTGG SEQ ID CTGAGACAATCCTTCCTTGCACTTTGAAACACTTTGAGCCTTTAAGAGATAGCCTGAGAA NO: 2862 NFIB ADXCRAD_U70862_at AAATGCATCAAGATATAGGTGTCCTTGCATTACCAACAATCCATAGTAAAACAATCATTT SEQ ID TACAAAGCCGCATACCAAAAGTAGACTAAAGTTTGAGCTGTCACAGATGGTAGGTCATTT NO: CCAAACTTGGCCTGGTGGGAGGAAAAATGGCCTGCAGATAGCCAGGTGACAGACTGTTAC 2863 CTGAGGTTTGTTATATAAATGTGGGACTTAATAAACTGCTATGAGCT PTPRK ADXCRAD_AU145587_at TGCTGGGCTGTTCTCTACCGAATACCATAAAACTGAATATTGTTCACCACTATGGTCGAT SEQ ID CTTTCTAACTTTAAAGAGTACACAACTGAACTCAATTACTCCAAAGATATGTGAAAACAC NO: AGAAAAATGACCCCTGTTAAAAGAGTAAACCTAGCTTTTGNTTTACTTTCCTTTTATATA 2864 AAAAAAGATGTACAGGGTTCTCTTCT CDC14B ADXCRAD_AK024886_at GAACATTTGGGTTTTCAATCAGAAGGTTTGTGACAGCAAAGTCATTGGAATAAATCTTTC SEQ ID TTCTTGTGGAGATGAAATATGTGGCTAGTCTTCGTGAGGCAGTCACCAATTAATCAACTT NO: CAGAAAAATAGAACCAAGCAGAATACTGAGGAGGGGTGCGTTACAGGAAATAAAAATGCT 2865 ATCAGAGGGCAACCCGCTCTGGTC CDC14B ADXCRAD_AK024886_x_at TAGACAGTCCCTGTTGATGAACATTTGGGTTTTCAATCAGAAGGTTTGTGACAGCAAAGT SEQ ID CATTGGAATAAATCTTTCTTCTTGATGGAGATGAAATATGTGGCTAGTCTTCGTGAGGCA NO: GTCACCAATTAATCAACTTCAGAAAAATAGAACCAAGCAGAATACTGAGGAGGGGTGCGT 2866 TACAGGAAATAAAAATGCTATCAGAGGGCAACCCGCTCTGGTC ARID5B ADXCRAD_AI289774_at GTATAATAATTCTGTCTGCCTTGTCCAGCAGTAATTGCCAGGACTCAATGGGTTGATACA SEQ ID AATGAAGTAGCATGTCAGAATTAGCTATCATGATCATTGTTATTTCTTCTCTAAATTGGT NO: GTTTTCCAAACCGTGGCATGCAGAGATGATTTTAGATGGTTCACAGGTAGACTTTTAA 2871 CRIM1 ADXCRAD_AA642418_s_at GACTTATACTCATGAGGTCTACCTACAGTCCATTCCCATTTAGGGGAAGAGAAAGGAGAG SEQ ID GAAATGGCCAAGAAGTCCATAAGAAGTGGACAGTGCTTTAACTTTTTCAAGTTTTGCTAA NO: CATATTTTATGTAAGTTATTCAATACCCCCATATTAAAGAGCAGCAGCTATTAAACACCA 2873 ACATTTATTAGCTGCTGGAAAGTAATAAATAACTTCAGCTAGTCCCCTTCAGTTTCCATA AAATTATAAAACCAACCATTTGACGTGAAAAAGCAGTTT FNDC3B ADXCRAD_AA703239_at TGACAAAGCCACTCCAATTTTGCTGGCCAAAAGGAAAAGTGTCCCGGGCACAAGGGCTGA SEQ ID GTTAATGGAGAGCAAGTGGTAATTATCTGCTCTATTAGATCCCTCTTCCTCCAGCCCAAT NO: TTCATGGGAGGCTTGGTTTATAAAACACTGGCTGTCTGACTAAACCTCAACAACAGATTA 2874 ACCATAAATGCATTCCTGGAATTTACGTTCTTCCCGCCTCAGTGTTGTGTAAAATTATCA GGGAACACAGACCCACAGGGTCAGGA VCAN ADXCRAD_BF590263_at ACATACTGTGTATTATTGTAGCTAGAGTCATTCCTTCTAAGCCAAAGGAGGTTTTATAAA SEQ ID AAAGAATCAATATTGGGCCAATCCCTTTGTGCCCTTTTTCTCTTTTTCTATGTGCATTTT NO: ATTTTTTGTCTACTCTTCTTCAAGTTGCTCTAAACTGAAATTAGGGAAGGAGTCTCACTT 2877 TCCATTACAGGTTTTTCTTTAAACATTAAATTAAGTGGATAAGGATTCAAAGTCATC SYNJ2 ADXCRAD_AK026758_at GGCACCTCTGGAGAGTTAGGACCCAGGCCTGCTCTCAGCACAATGAGAGGAAAACTAACC SEQ ID CTGAACTCCCTGCCACCCCCCACCCCTGGCCCCTGGAATGTGTTAGAGTGTAGAT NO: 2884 SYNJ2 ADXCRAD_AK026758_x_at GGCACCTCTGGAGAGTTAGGACCCAGGCCTGCTCTCAGCACAATGAGAGGAAAACTAACC SEQ ID CTGAACTCCCTGCCACCCCCCACCCCTGGCCCCTGGAATGTGTTAGAGTGTAGATTTGGA NO: AAAGAAACCTGCGCCAGGCATGGTGCC 2885 CDC42BPA ADXCRAD_AK027000_at AGGAGACTCCTAGAGTGGTCCCAATGGAAACCAATGAGGGCTTGGGATGCAGCAGGGGCA SEQ ID GAAGGAGAGAAGATGGTAGATTCTCCAGATATATTTTCAGAGTTAAAAGCAGTAAGACTT NO: GATGATGAATTAGTCATGGAAAAGTAAGGGAGAGAGTTAAAGATGACTCCCAGACTTCCT 2886 GCTAGGGCCTTAGTATGATACCATTTACTCCCATTTACCACCGTTTAAGAAGGGGCTGAG GCAGGACATTCCACGCATGTCCAAAGGTCCCGAGGTAGCAA NFIB ADXCRAD_T90642_s_at CTTTGACCCTGCACAATGACCTTTGCATCAGCCAAACTCATTGCCATGACAACTCTTTGT SEQ ID ACTGTGTCCGTGCCACAGATCTGTTGGTCACAT NO: 2887 EGFR ADXCRAD_AU156822_x_at CCATGGCAATCTGTCTTGCTGCTGTGCAGTCCTTCCCTGGGTGGCTGCAGGGGCAAACAC SEQ ID AGGGTTTGTNGGTCCTGGGTCTTATAAAAATCAGGTACAAATTGACACNTNTATTTAAAA NO: GGANAAATTGCCAAATGANACAAAATGTTTTCCTTATGCAAATTTCAT 2890 BCL6 ADXCRAD_AI733564_at GGGCGCGGAGTGGAGATTGGCTCTCTGAGGTGGTCAGGGGCCCTGTGACAGCTTGGGACT SEQ ID TTCAGCACCTGGTTTGGGGTCATTTATCTGCTCAACTGTCAGACCCCCCACCCCCAAACC NO: CCAGCCACCAACACAACCATCGTAGAAGGGAACACAACACAGAGGGTCTTTTTTCA 2891 KCMF1 ADXCRAD_R53065_at TCGTCAGTGTGATATTTTCCAAGGTAAGTCTGAATCGTGAGTGGTCAGCACACATGGTGG SEQ ID GCTGCTATCCGATAGGACAATTCAACAGACACTGCTAATTAGCATACTATATATTTAAAA NO: ATGGACTTTTATGGGGAAACTAGTGTCTTGTTAATTGTCATGAAAGGTTCTCGTGGGCAA 2892 AATTAAATGGATTCAAGGCTGGCCAGAATAGCTTTCATGACTAGGGGGTAAGAATCCATG AACTTTCCTTCAGTCCCTAGCGACAGTGGCTGAGG MAPK1 ADXCRAD_AA088464_at AATAAAAACCTCAGCTGAAAAGCTAATAACTCCAGAATGCAGGTTGAAAGCAAGCTTAAA SEQ ID GGTCATCTAGGCTGGGGTCAGTAGCTCACGCCTGCAATCCCAACACCCTGGGAGGCCCAG NO: GTGAGAGGACCGCTCGAGCCCNGGAGGTAAAGGCCGCAGCGAGCTATGACCGCGCCACTG 2893 CACACCAGCCTGTGCCACAAAGTAGA MAPK1 ADXCRAD_AA088446_x_at AATAAAAACCTCAGCTGAAAAGCTAATAACTCCAGAATGCAGGTTGAAAGCAAGCTTAAA SEQ ID GGTCATCTAGGCTGGGGTCAGTAGCTCACGCCTGCAATCCCAACACCCTGGGAGGCCCAG NO: GTGAGAGGACCGCTCGAGCCCNGGAGGTAAAGGCCGCAGCGAGCTATGACCGCGCCACTG 2894 CACACCAGCCTGTGCCACAAAGTAGA MICALL1 ADXCRAD_W46406_at ACAGAGCAGACAGACCAGTGATGACCATGGGCGGGACGAAGCCTCTTCCCTGGACCGGGG SEQ ID TGGCAGAGGAAAGCCTAAGTGAGGGGTCAGACTATAAACGTTAAGGAACCCGAGATNAGC NO: ACCTGCTTCAAGTGCACCCTTCCTACCTNACAACCAGGGACCAGAACTGCAANCTTTGGG 2898 GACAGCACTTGGGAGCAGCTAACAGAGCACTCACCTGCCCCAAGANGGCCGTCGCAGCCC TGGTCCTGGCAAGGGAAGCT EHD2 ADXCRAD_AI417917_at GAGCAGATCACCTGAATTGCGAGTCGAGACCAGCT SEQ ID NO: 2899 EHD2 ADXCRAD_AI417917_s_at TGGCCCAGCAATCCTTAAGTCCAGATTACCAGCTGTGGGGAGGCTTCCAGGGGGCCAGGA SEQ ID GCAGGCTTGGCAGTTCCAGCCACAGACACGTGGGTGAGGACGGAAATATCTCCAAGGGGG NO: CACAGTAT 2900 EHD2 ADXCRAD_AI417917_x_at GGCCCAGCAATCCTTAAGTCCAGATTACCAGCTGTGGGGAGGCTTCCAGGGGGCCAGGAG SEQ ID CAGGCTTGGCAGTTCCAGCCACAGACACGTGGGTGAGGACGGAAATATCTCCAAGGGGGC NO: ACAGTATCAGAGGAGCAGGATGGAAGGGCTTTTCTGCCTGCTACGGATCCTTTTAAAGAA 2901 ATGGTGTGAAGCCGGCCGGNGCTCATGCCTGAATCCCATCACTTTGGAGGCCGAGCGAGC AGATCACCTGAATTGCGAGTCGAGACCAGCTGCCAAC

Sequencing

Expression levels of biomarkers may be determined using sequencing technologies, such as next generation sequencing platforms (e.g., RNA-Seq), as described in Mortazavi et al., Nat. Methods 5: 621-628, 2008, hereby incorporated by reference. Sequencing methods for expression profiling offer broader dynamic range than microarray and offer the possibility of quantifying sequences for which pre-designed probes are not available (e.g., novel transcripts, novel splice variants, or low-abundance transcripts). RNA-Seq is a robust technology for monitoring expression by direct sequencing the RNA molecules in a sample. In certain embodiments, this methodology includes fragmentation of RNA to an average length of, e.g., 200 nucleotides, conversion to cDNA by random priming, and synthesis of double-stranded cDNA (e.g., using the Just cDNA DoubleStranded cDNA Synthesis Kit from Agilent Technology). Then, the cDNA is converted into a molecular library for sequencing by addition of sequence adapters for each library (e.g., from Illumina®/Solexa), and the resulting 50-100 nucleotide reads are mapped onto the genome.

Exemplary sequencing platforms suitable for use according to the invention include, but are not limited to, 454 pyrosequencing, Illumina sequencing by synthesis, SOLiD sequencing, Ion Torrent sequencing, and PacBio RS sequencing.

Other systems

Expression levels of biomarkers may, alternatively, be determined using any other methods known in the art. For example, biomarker expression may be assayed using a NanoString nCounter system. In this system, a capture probe and reporter probe are hybridized to a target nucleic acid (e.g., a biomarker of the invention). The capture probe is used to immobilize the probe/target complex for isolation and data collection, and the reporter probe carries a combination of fluorescent moieties representing a “color code,” which can be identified and tabulated to count the number of such target molecules present in the original solution. In some embodiments, biomarker expression is assayed using a protein array to measure the expression of one or more polypeptide gene products (e.g., proteins, protein fragments, protein complexes, or peptides) of the biomarker genes. The protein array can include protein binding moieties (e.g., antibodies, antibody fragments, scFvs, or other protein binding agents) capable of detectably binding to such polypeptide gene products, such as those described herein.

Methods of Treatment

The diagnostic methods of the present invention permit the assessment of whether a given subject is likely to be sensitive or resistant to treatment with a target drug, and can therefore be used to direct the subject's treatment. Exemplary target drugs include chemotherapeutic agents, such as 5-FU, capecitabine, tegafur, irinotecan, oxaliplatin, cetuximab, leucovorin, SN-38, everolimus, temsirolimus, bleomycin, lomustine, depsipeptide, carboplatin, bortezomib, erlotinib, gemcitabine, mitoxantrone, cisplatin, busulfan, epirubicin, arsenic trioxide, bendamustine, vincristine, fulvestrant, teniposide, adriamycin, decitabine, estramustine, etoposide, azaguanine, aclarubicin, mitoxantrone, mitomycin, paclitaxel, taxotere, dexamethasone, ara-c, methylprednisolone, methotrexate, methyl-gag, belinostat, carboplatin, idarubicin, melphalan, IL4-PR38, valproic acid, all-trans retinoic acid (ATRA), cytoxan, topotecan, suberoylanilide hydroxamic acid (SAHA, vorinostat), leukeran, fludarabine, vinblastine, dacarbazine, hydroxyurea, tegafur, daunorubicin, mechlorethamine, streptozocin, carmustine, mercaptopurine, dactinomycin, tretinoin, ifosfamide, tamoxifen, floxuridine, thioguanine, PSC 833, herceptin, bevacizumab, celecoxib, iressa, anastrozole, letrozole, rituximab, radiation, and histone deacetylase (HDAC) inhibitors, as well as prodrugs, derivatives, metabolites, enantiomers, and analogs thereof. A subject found to be sensitive to a target drug according to the methods of the invention may be preferentially selected for treatment with the target drug or drug combinations including the target drug. Thus, the present invention further features methods of treatment that leverage the improved understanding of the subject's drug responsiveness profile to improve outcomes. For example, a subject can be identified as sensitive to a target drug by determining the expression level of one or more biomarkers of sensitivity and/or resistance in a biological sample obtained from the subject, and subsequently administered the target drug (e.g., alone or as part of a combination therapy). Alternatively, a subject can be, e.g., identified as resistant to a target drug by determining the expression level of one or more biomarkers of sensitivity and/or resistance in a biological sample obtained from the subject, and subsequently administered a drug other than the target drug or a combination therapy predicted to have a greater effect than administration of the target drug alone. In some embodiments, the level of expression of one or more biomarkers of sensitivity to a target drug are assayed in a sample from a subject. In other embodiments, the level of expression of one or more biomarkers of resistance to a target drug are assayed in a sample from a subject. In still other embodiments, the level of expression of one or more biomarkers of sensitivity and the level of expression of one or more biomarkers of resistance to a target drug are assayed in a sample from a subject.

Administration and Dosage of Target Drugs

Routes of administration, frequency of administration, and/or dosage of target drugs (e.g., 5-FU, irinotecan, or oxaliplatin) will vary from individual to individual, and may be readily established using standard techniques. Once a patient has been determined to be responsive to one or more target drugs, according to the methods described herein, the target drug(s) of the invention can be administered to the patient by the usual means known in the art, for example, by injection, intravenously, orally, subcutaneously, intraperitoneally, intramuscularly, by infusion, by infiltration, by irrigation, intra-articularly, by inhalation, topically, rectally, vaginally, cutaneously, nasally, transdermally, or by ocular administration and the like. In certain embodiments, the target drug is administered intravenously. In particular embodiments, 5-FU, irinotecan, and/or oxaliplatin are administered by intravenous injection. For administration by injection, infiltration, or infusion, a target drug may be suspended or dissolved, as known in the art, in a vehicle suitable for injection, infiltration, or infusion. Such vehicles include, e.g., isotonic saline, buffered or unbuffered, and the like. Depending on the intended use, they also may contain other ingredients, including other active ingredients, such as isotonicity agents, sodium chloride, pH modifiers, colorants, preservatives, antibodies, enzymes, antibiotics, antifungals, antivirals, other anti-infective agents, and/or diagnostic aids such as radio-opaque dyes, radiolabeled agents, and the like, as known in the art. Compositions including a target drug may include a simple solution or suspension of the target drug or a pharmaceutically acceptable salt of the target drug, in distilled water or saline. Alternatively, a target drug may be delivered by other means, such as intranasally, by inhalation, or in the form of liposomes, nanocapsules, vesicles, and the like. Compositions for intranasal administration usually take the form of drops, sprays containing liquid forms (solutions, suspensions, emulsions, liposomes, etc.) of the active compounds. Administration by inhalation generally involves formation of vapors, mists, dry powders or aerosols, and again may include solutions, suspensions, emulsions and the like containing the active therapeutic agents.

Administration of a target drug of the invention to a subject can be performed according to, e.g., courses of therapy standard in the art. A target drug can be administered at a frequency of, for example, at least once hourly, once daily, twice daily, once weekly, once every two weeks, once every three weeks, once every four weeks, once monthly, once every two months, once every three months, once every six months, or once every year. The administration can be repeated at such a frequency for a certain period of time, followed by a period without treatment. In certain embodiments, a target drug is administered once daily for up to four days. In particular embodiments, the administration is repeated every 30 days or every month. Such repeated administrations can occur over a course of therapy lasting a specified length of time (e.g., at least 1 week, 2 weeks, 3 weeks, 1 month, 2 months, 3 months, 6 months, 8 months, 10 months, 12 months, 18 months, 24 months, 36 months, 48 months, or 60 months). In certain embodiments, administration of a target drug is repeated for at least 12 months or 60 months.

A subject may be monitored or assessed according to the methods of the invention before, during, or after treatment. For example, a subject may be assessed for target drug responsiveness between administrations of the target drug. Multiple assessments can be performed over the course of therapy, and the results combined to determine change in responsiveness of the subject to the target drug over time. Each of the assessments can involve determining the expression level of the same biomarkers of responsiveness, or can involve determining the expression level of different biomarkers (e.g., selecting one or more distinct biomarkers per assessment, or varying only a subset of the biomarkers tested between individual assessments).

A suitable dose or therapeutic amount of a given target drug is generally an amount of a compound that, when administered as described above, is capable of treating a disease (e.g., by killing or slowing the growth of cancers or cancer cells). In general, an appropriate dosage and treatment regimen provides the active compound(s) in an amount sufficient to provide therapeutic and/or prophylactic benefit. In certain embodiments, a dose includes about 0.1-5000 mg of the active ingredient (e.g., a target drug), for example, about 0.1 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 10 mg, 12 mg, 15 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg, 80 mg, 85 mg, 90 mg, 100 mg, 125 mg, 130 mg, 150 mg, 175 mg, 180 mg, 200 mg, 250 mg, 300 mg, 350 mg, 370 mg, 400 mg, 450 mg, 500 mg, 600 mg, 700 mg, 800 mg, 900 mg, 1000 mg, 1500 mg, 2000 mg, 2500 mg, 3000 mg, 4000 mg, or 5000 mg of the active ingredient. In particular embodiments, the dosage is 800 mg per day. Dosage may vary from subject to subject. For example, a drug may be administered in a particular amount per amount of a subject's body weight, e.g., milligram per kilogram of the subject's body weight (mg/kg), or a drug may be administered in a particular amount per amount of a subject's body surface area, e.g., milligrams per square meter of the subject's body surface area (mg/m²). Body surface area can be estimated, for example, based on a subject's height and weight.

Therapeutic and/or prophylactic effect (e.g., benefit) can be monitored by establishing an improved clinical outcome (e.g., more frequent remissions, complete or partial, longer disease-free survival, decreased morbidity, or an improvement in one or more standard tests or assays known in the art for the assessment of the disease, condition, or disorder status) in treated patients as compared to non-treated patients.

A therapeutic amount of a target drug described herein refers to an amount effective to yield the desired therapeutic response, such as, for example, an amount effective to delay the growth of a cancer or to cause a cancer to shrink or not metastasize. If what is administered is not the target drug but an enantiomer, prodrug, salt, or metabolite of the target drug, then the term “therapeutically effective amount” means an amount of such material that produces in the patient the same blood concentration of the active component of the target drug in question that is produced by the administration of a therapeutically effective amount of the target drug itself.

Target drugs, such as those described herein, may be used alone or in combination with one or more additional therapeutic agents suitable for treatment of a particular indication. For example, a target drug of the invention may be co-administered to a subject who has, or is at risk for developing, cancer with conventional anti-cancer therapeutic regimens such as surgery, irradiation, chemotherapy and/or bone marrow transplantation (autologous, syngeneic, allogeneic, or unrelated) or in combination with conventional therapeutic regimens to treat age-related cataracts, spinal injuries, wounds or congenital defects. Such combination therapies are described in further detail below.

Subjects that can be treated with a target drug as described herein, and/or the pharmaceutically acceptable salts, prodrugs, enantiomers, and metabolites of such compounds, according to the methods of the invention include, for example, patients that have been diagnosed as having any of the diseases or disorders described herein. As used herein, a “patient” or a “subject” refers to any animal (e.g., a mammal), preferably a human. The sensitivity and/or resistance of a subject to treatment with a target drug can be determined using the devices and methods of the invention, e.g., by measuring the expression level of one or more biomarkers of sensitivity and/or resistance to the target drug (e.g., 5-FU, irinotecan, or oxaliplatin). A subject may be suffering from, in remission from, or susceptible to developing a cancer (e.g., a colon cancer). Accordingly, pharmaceutical compositions including a target drug may be used to prevent the development or progression of a cancer or other disorder, or delay its appearance or reappearance, or to treat a patient afflicted with a cancer. A cancer or other disorder treatable by the methods of the invention may be diagnosed using the diagnostic methods described herein and/or by criteria generally accepted in the art. In the case of cancer, target drugs may be administered either prior to or following surgical removal of primary or other tumors and/or treatment such as administration of radiotherapy or conventional chemotherapeutic drugs, or bone marrow transplantation (autologous, allogeneic, or syngeneic).

5-fluorouracil

5-fluorouracil (5-FU) is an antineoplastic suicide inhibitor commonly used as a chemotherapeutic agent in the treatment of cancer (e.g., colon cancer, rectal cancer, anal cancer, breast cancer, esophageal cancer, stomach cancer, pancreatic cancer, and skin cancer). 5-FU can be administered to a subject in, e.g., its active form, or administered in the form of a prodrug, such as capecitabine or tegafur. The effective dosage and maximally-tolerated dosage of 5-FU can vary dramatically from subject to subject. As such, there is a need for methods, such as those described herein, for assessing a subject's responsiveness (e.g., sensitivity or resistance) to 5-FU treatment.

5-FU is generally administered to subjects intravenously. 5-FU packaged for intravenous administration is commonly available in 50 mL or 100 mL packages containing 50 mg/mL of 5-FU dissolved in saline solution (water, pH adjusted to 8.6 to 9.4 with sodium hydroxide). The daily dosage of 5-FU delivered to a subject generally depends on the subject's weight, e.g., 12 mg 5-FU daily per kilogram subject weight (mg/kg), but is not to exceed 800 mg per day. A standard dosage regimen for 5-FU includes, e.g., intravenous administration of 12 mg/kg once daily for four successive days, followed by 6 mg/kg on the 6^(th), 8^(th), 10^(th), and 12^(th) days unless toxicity occurs. Subjects identified as “poor risk” may be, e.g., administered only 6 mg/kg daily for 3 days, followed by 3 mg/kg on the 5^(th), 7^(th), and 9^(th) days unless toxicity occurs. A maintenance dosage of 10-15 mg/kg per week can be administered as a single dose when toxic signs from an initial dosage regimen have subsided. A course of treatment can be repeated, e.g., every 30 days after the last day of the previous round of treatment. Such repetition can occur up to, e.g., 9 to 45 times over periods of about 12 to 60 months.

5-FU can also be administered orally (e.g., in the form of the produg capecitabine, which is enzymatically converted to 5-FU upon ingestion) for the treatment of, e.g., colon cancer, rectal cancer, breast cancer, gastric cancer, or esophageal cancer. In some embodiments, capecitabine is orally administered in the form of tablets. In certain embodiments, each tablet contains 150 mg capecitabine or 500 mg capecitabine. In particular embodiments, tablets are administered twice daily, once in the morning and once in the evening (e.g., after a meal), for a course of 14 days, followed by no treatment for 7 days. This cycle of 14 days and 7 days can be, e.g., repeated every 3 weeks. The total daily dosage of capecitabine administered to a subject can be, e.g., 2500 mg/m². Another 5-FU prodrug, tegafur, is used to treat, for example, stomach cancer, breast cancer, gall bladder cancer, lung cancer, colon cancer, rectal cancer, cancer of the head and neck, liver cancer, or pancreatic cancer. In certain embodiments, tegafur is administered alongside one or more additional therapeutic agents (e.g., gimeracil, oteracil, and/or uracil). The combination of tegafur and uracil can be, for example, orally administered at a daily dosage of 300-400 mg/mg² in cycles of, e.g., 5 days of treatment followed by 2 days off treatment, or at a daily dosage of 300-600 mg/mg² in cycles of, e.g., 28 days of treatment followed by one week off treatment. In certain embodiments, tegafur and uracil can be administered on a long term basis (e.g., for about 6 months up to about 11 years).

5-FU treatment can be combined with other cancer treatments. For example, 5-FU can be administered in combination with leucovorin, irinotecan, and/or oxaliplatin. In certain embodiments, leucovorin is administered intravenously at 200 mg/m² over a minimum of 3 minutes, followed by intravenous administration of 5-FU at 370 mg/m²; or leucovorin is administered intravenously at 20 mg/m² followed by intravenous administration of 5-FU at 425 mg/m². Such treatments can be performed daily for, e.g., a five day course of treatment. A course of treatment may be repeated at, e.g., four week intervals for two courses, followed by repetition at, e.g., 4-5 week intervals. 5-FU and leucovorin are generally administered separately to avoid precipitation. In some embodiments, 5-FU can be administered in combination with irinotecan, e.g., in a FOLFIRI regimen, as described in detail below. In alternate embodiments, 5-FU can be administered in combination with oxaliplatin, e.g., in a FOLFOX regimen, such as the FOLFOX4 regiment described in detail below.

Irinotecan

Irinotecan, a topoisomerase I inhibitor, is a chemotherapeutic agent commonly used in the treatment of cancers (e.g., colon cancer, rectal cancer, pancreatic cancer, ovarian cancer, glioblastoma, or lung caner). In the body, irinotecan is converted into its metabolite, SN-38, which has significantly greater potency as a topoisomerase inhibitor than irinotecan. Irinotecan monotherapy can include, for example, 125 mg/m² intravenous infusion over 90 minutes on each of days 1, 8, 15, 22, followed by 2 weeks off treatment. Alternatively, irinotecan monotherapy can include, e.g., 350 mg/m² intravenous infusion over 30-90 minutes, administered once every three weeks. Irinotecan is often administered in combination with other chemotherapeutic agents (e.g., 5-FU and/or leucovorin). In certain embodiments, irinotecan is administered in combination with 5-FU and leucovorin, e.g., in a FOLFIRI regimen. An exemplary FOLFIRI cycle includes, in order, (i) intravenous co-administration of irinotecan (180 mg/m² over 90 minutes) with leucovorin (400 mg/m² (or 2×250 mg/m²) over 120 minutes, (ii) intravenous administration of 5-FU (400-500 mg/m² bolus), and (iii) intravenous administration of 5-FU (2400-3000 mg/m² intravenous infusion over 46 hours). Such a cycle can be repeated, e.g., every two weeks. An alternate FOLFIRI regimen can include, for example, a 180 mg/m² intravenous infusion of irinotecan over 30-90 minutes, followed by infusion with leucovorin and 5-fluorouracil, on each of days 1, 15, and 29, with the subsequent cycle beginning on day 43. A FOLFIRI cycle can also include, e.g., 125 mg/m² intravenous infusion of irinotecan over 90 minutes, followed by bolus doses of leucovorin and 5-fluorouracil, on each of days 1, 8, 15, and 22. Dosages can vary from cycle to cycle or from subject to subject, as required.

Oxaliplatin

Oxaliplatin is a platinum-based antineoplastic agent commonly used to treat cancers (e.g., colon cancer and rectal cancer). Oxaliplatin can be administered as a monotherapy, e.g., by intravenous administration of 130 mg/m² over two hours, once every three weeks. More commonly, however, oxaliplatin is given in combination with, e.g., 5-FU and/or leucovorin. For example, the FOLFOX4 regimen is a two-day regimen recommended for, e.g., stage III colon cancer. On day 1 of FOLFOX4, simultaneous administration of 85 mg/m² of oxaliplatin and 200 mg/m² of leucovorin by intravenous infusion over two hours, followed by 400 mg/m² 5-FU delivered as an intravenous bolus over 2-4 minutes, followed by 600 mg/m² of 5-FU as a 22-hour, continuous intravenous infusion. On day 2 of FOLFOX4, 200 mg/m² of leucovorin is administered by intravenous infusion over two hours, followed by a 400 mg/m² 5-FU bolus given intravenously over 2-4 minutes, followed by 600 mg/m² of 5-FU as a 22-hour, continuous intravenous infusion. Such two-day cycles can be repeated about 12 times, once every two weeks. Dosages can vary from cycle to cycle or from subject to subject, as required.

Combination Therapies

Once a patient is assessed to be responsive to one or more target drugs, according to the methods of the invention, one or more of the target drug(s) (e.g., 5-FU, irinotecan, or oxaliplatin, or an analog thereof) can be administered in combination with one or more additional therapies, including but not limited to therapeutic agents (e.g., compounds, pharmaceuticals, or compositions), treatments, therapies, medical procedures, and combinations thereof. Such therapies can also be administered in lieu of treatment with the target drug (e.g., 5-FU, irinotecan, or oxaliplatin, or analog thereof), if the subject is, for example, identified as resistant to the target drug according to the methods of the invention. Methods, devices, and kits of the present invention can be used to determine the responsiveness of a subject to such combination therapies. In such combination therapies, target drugs of the invention may be formulated with or administered concurrently with, prior to, or subsequent to, one or more other desired therapies. The particular combination of therapies to employ in a combination regimen will take into account compatibility of the desired therapeutics and/or procedures and the desired therapeutic effect to be achieved. It will also be appreciated that the therapies employed may achieve a desired effect for a condition, disease, or disorder, or they may achieve different effects (e.g., control of any adverse effects).

In general, for use in treatment, the target drugs described herein may be used alone, as mixtures of two or more agents, or in combination with other agents, compounds, and/or pharmaceuticals. Examples of other agents that can be combined with the compounds described herein include agents that are known to be used for the treatment of cancer (e.g., colon cancer). Other potential agents to combine with the compounds described herein can include agents for the treatment of different yet associated or related symptoms or indications. Depending on the mode of administration, the agents may be formulated into suitable compositions to permit facile delivery. Each component of a combination therapy may be formulated in a variety of ways that are known in the art. For example, the first and second agents of the combination therapy may be formulated together or separately. The target drug of the present invention and additional agent may be suitably administered to the patient at one time or over a series of treatments.

The combination therapy may provide “synergy” and prove “synergistic,” i.e., the effect achieved when the active ingredients used together is greater than the sum of the effects that results from using the ingredients separately. A synergistic effect may be attained when the active ingredients are: (1) co-formulated and administered or delivered simultaneously in a combined, unit dosage formulation; (2) delivered by alternation or in parallel as separate formulations; or (3) by some other regimen. When delivered in alternation therapy, a synergistic effect may be attained when the compounds, agents, and/or treatments are administered or delivered sequentially, e.g., by different injections in separate syringes. Suitable dosages for any of the above co-administered agents are those presently used and may be lowered due to the combined action (synergy) of a compound of the present invention and other co-administered agents or treatments.

Each component of a combination therapy, as described herein, may be formulated in a variety of ways that are known in the art. For example, the first and second agents of the combination therapy may be formulated together or separately. The individually or separately formulated agents can be packaged together as a kit. Non-limiting examples include, but are not limited to, kits that contain, e.g., a liquid in a container (e.g., a bag or a vial), two pills, a pill and a powder, a suppository, two topical creams, etc. The kit can include optional components that aid in the administration of the unit dose to patients, such as vials for reconstituting powder forms, syringes for injection, customized IV delivery systems, inhalers, etc. Additionally, the unit dose kit can contain instructions for preparation and administration of the compositions. The kit may be manufactured as a single use unit dose for one patient, multiple uses for a particular patient (at a constant dose or in which the individual compounds may vary in potency as therapy progresses); or the kit may contain multiple doses suitable for administration to multiple patients (“bulk packaging”). The kit components may be assembled in cartons, blister packs, bottles, tubes, and the like. Two or more components may be mixed together in a liquid, tablet, capsule, or other vehicle, or may be partitioned.

Exemplary therapies that can be combined with target drugs of the present invention can include, for example, drugs (e.g., chemotherapeutic agents) and/or non-pharmacological therapies (e.g., surgery or radiation therapy). Chemotherapeutic agents suitable for, e.g., combination with target drugs of the present invention (in particular, 5-FU, irinotecan, and/or oxaliplatin) may include, for example, one or more of the following: 5-FU, capecitabine, tegafur, irinotecan, oxaliplatin, cetuximab, leucovorin, SN-38, everolimus, temsirolimus, bleomycin, lomustine, depsipeptide, carboplatin, bortezomib, erlotinib, gemcitabine, mitoxantrone, cisplatin, busulfan, epirubicin, arsenic trioxide, bendamustine, vincristine, fulvestrant, teniposide, adriamycin, decitabine, estramustine, etoposide, azaguanine, aclarubicin, mitoxantrone, mitomycin, paclitaxel, taxotere, dexamethasone, ara-c, methylprednisolone, methotrexate, methyl-gag, belinostat, carboplatin, idarubicin, melphalan, IL4-PR38, valproic acid, all-trans retinoic acid (ATRA), cytoxan, topotecan, suberoylanilide hydroxamic acid (SAHA, vorinostat), leukeran, fludarabine, vinblastine, dacarbazine, hydroxyurea, tegafur, daunorubicin, mechlorethamine, streptozocin, carmustine, mercaptopurine, dactinomycin, tretinoin, ifosfamide, tamoxifen, floxuridine, thioguanine, PSC 833, herceptin, bevacizumab, celecoxib, iressa, anastrozole, letrozole, rituximab, radiation, and histone deacetylase (HDAC) inhibitors.

Methods for Identifying Biomarkers of Drug Sensitivity or Resistance

The invention features methods for identifying biomarkers of sensitivity or resistance to a drug of interest (e.g., 5-FU, irinotecan, or oxaliplatin). Such methods can involve, for example, an algorithm based on growth inhibition values (GI50) of cell lines (e.g., NCI60 cell lines) subjected to treatment with a drug (e.g., 5-FU, irinotecan, oxaliplatin, or a metabolite thereof), followed by measurement of gene expression (e.g., using an Affymetrix HG-U133A array).

In certain embodiments, the gene expression measurements of NCI60 cancer cell lines are obtained from a publically available database (e.g., the National Cancer Institute and the Massachusetts Institute of Technology). Each dataset is normalized so that sample expression measured by different chips could be compared. The preferred method of normalization is the logit transformation, which is performed for each gene yon each chip:

logit(y)=log [(y−background)/(saturation−y)],

where background is calculated as the minimum intensity measured on the chip minus 0.1% of the signal intensity range: min−0.001*(max−min), and saturation is calculated as the maximum intensity measured on the chip plus 0.1% of the signal intensity range: max+0.001*(max−min). The resulting logit transformed data is then z-transformed to mean zero and standard deviation 1.

Next, gene expression is correlated to cancer cell growth inhibition. Growth inhibition data (GI50) of the NCI60 cell lines in the presence of any one of thousands of tested compounds is obtained from the NCI. The correlation between the logit-transformed expression level of each gene in each cell line and the logarithm of GI50 (the concentration of a given compound that results in a 50% inhibition of growth) can be calculated, e.g., using the Pearson correlation coefficient or the Spearman Rank-Order correlation coefficient. Instead of using GI50s, any other measure of patient sensitivity to a given compound may be correlated to a subject's gene expression levels. Since a plurality of measurements may be available for a single gene, the most accurate determination of correlation coefficient can be, e.g., the median of the correlation coefficients calculated for all probes measuring expression of the same gene.

The median correlation coefficient of gene expression measured on a probe to growth inhibition or patient sensitivity is calculated for all genes, and genes that have a median correlation above, e.g., 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 0.95, or 0.99 can be used as biomarker genes. Preferably, the correlation coefficient of a biomarker gene will exceed 0.3. This can be repeated for multiple drug compounds to be tested. The result is a list of marker genes that correlates to sensitivity for each drug tested. Such methods are further described in PCT Publication No. WO 2011/135459, which is incorporated herein in its entirety.

Devices and Kits

The present invention features devices and kits for determining the expression level of one or more biomarkers of sensitivity and/or resistance to a target drug. Devices of the invention can include, for example, microarrays, protein arrays, or chips containing one or more probes suitable for hybridization to one or more biomarkers of interest. Kits of the invention can include, for example, reagents for microarray analysis of gene expression, reagents for sequencing (e.g., Sanger sequencing or next generation sequencing), and/or reagents for PCR-based techniques, as well as instructions for their use. Exemplary next generation sequencing platforms suitable for use with the present invention include the MiSeq and HiSeq platforms (Illumina), the SOLiD platform (Applied Biosystems), Roche 454 pyrosequencing, Ion Torrent/Ion Proton (Life Technologies), PacBio RS, Oxford Nanopore, and other NGS platforms known in the art.

A device or kit of the invention may include pre-designed probes and/or primers targeting the one or more biomarkers of interest such as those described herein (see, e.g., Tables 1-6). Such probes can be, e.g., oligonucleotide probes identical to or sharing at least 85%, 90%, 95%, or 99% identity to the one or more biomarkers or to a nucleic acid complementary to the one or more biomarkers (e.g., the probe includes at least about 5, 10, 15, or 20 contiguous nucleic acid residues that are complementary to the one or more biomarkers). The probes can be complementary to, e.g., at least 5, 8, 12, 20, 30, 40, 60, 80, 100, 150, or 200 consecutive nucleotides (or nucleotide analogs) of the one or more of the biomarkers. The probes may be, e.g., 5-20, 25, 5-50, 50-100, or over 100 nucleotides long, and may be deoxyribonucleic acids (DNA) or ribonucleic acids (RNA). Consecutive nucleotides within the probes (e.g., 5-20, 25, 5-50, 50-100, or over 100 consecutive nucleotides) may also appear as consecutive nucleotides in one or more of the biomarkers described herein beginning at or near, e.g., the first, tenth, twentieth, thirtieth, fortieth, fiftieth, sixtieth, seventieth, eightieth, ninetieth, hundredth, hundred-fiftieth, two-hundredth, five-hundredth, or one-thousandth nucleotide of one or more of the biomarkers listed in one or more of Tables 1-6 (e.g., NT5E). In certain embodiments, devices of the present invention can include microarrays having one or more oligonucleotide probes, as described in detail below.

Probes that may be employed on devices (e.g., microarrays) of the invention include oligonucleotide probes having sequences complementary to or identical to (or sharing at least 85%, 90%, 95%, or 99% identity to) any of the target biomarker sequences described herein (e.g., NT5E). Additionally, probes employed on devices (e.g., microarrays) of the invention may also include proteins, peptides, or antibodies that selectively bind any of the oligonucleotide probe sequences or their complementary sequences. Exemplary biomarkers of drug sensitivity and resistance are listed in Tables 1-6 alongside exemplary Affymetrix probes useful for detecting the associated biomarkers.

Any of the devices or kits described herein can be adapted to include a solid support. Exemplary solid supports include a glass or a polymer surface, including one or more of a well, a plate, a wellplate, a tube, an array, a bead, a disc, a microarray, a protein array, or a microplate. In particular, the solid support can be adapted to allow for automation of any one of the methods described herein (e.g., PCR, microarray, next generation sequencing, or NanoString). Alternatively, microfluidics or microdroplets could be used (e.g., for polony-based sequencing or 454 pyrosequencing).

Devices

Devices of the present invention can be useful, e.g., for detecting the level of expression of at least one biomarker of responsiveness (e.g., sensitivity or resistance) to a target drug (e.g., 5-FU, irinotecan, or oxaliplatin). In some embodiments, the device includes at least one single-stranded nucleic acid (e.g., a probe) having at least 85% sequence identity (e.g., 85%, 90%, 95%, 97%, 98%, 99%, or 100% sequence identity) to a nucleic acid sequence that is complementary or identical to at least 5 consecutive nucleotides of one or more biomarkers, in which the at least one single-stranded nucleic acid is sufficient for the detection of the level of expression of the one or more biomarkers. The device may detect the expression level of a given biomarker by specific hybridization between the single-stranded nucleic acid and the biomarker (e.g., an mRNA, genomic DNA, or non-coding RNA), a nucleic acid encoding the biomarker (e.g., an mRNA), or a complementary nucleic acid thereof. In certain embodiments, the device includes a microarray. In alternate embodiments, the device includes reagents and materials for next generation sequence (e.g., sequencing by synthesis). In further embodiments, the device includes NanoString reagents and at least one nCounter cartridge. In additional embodiments, the device includes a protein array, which contains one or more protein binding moieties (e.g., proteins, antibodies, nucleic acids, aptamers, affibodies, lipids, phospholipids, small molecules, labeled variants of any of the above, and any other moieties useful for protein detection as well known in the art) capable of detectably binding to the polypeptide gene product(s) of one or more biomarkers of sensitivity and/or resistance (e.g., those shown in Tables 1-6) to treatment with a target drug (e.g., 5-FU, irinotecan, or oxaliplatin). In some embodiments, the target drug is 5-FU and the biomarker is selected from the biomarkers of Table 1 or 2. In alternate embodiments, the target drug is irinotecan and the biomarker is selected from the biomarkers of Table 3 or 4. In other embodiments, the target drug is oxaliplatin and the biomarker is selected from the biomarkers of Table 5 or 6.

Kits

Kits of the present invention can be used for diagnosing the responsiveness of a subject to a treatment for cancer (e.g., 5-FU, irinotecan, or oxaliplatin, or an analog thereof) and/or for treating the subject for cancer. Kits of the invention can include reagents and/or materials for, e.g., collecting and/or purifying nucleic acids from biological samples (such as those obtained from a subject to be treated with a target drug of the invention), reagents for amplifying such nucleic acids to produce an amplified sample, and/or at least one device of the invention as described herein. Reagents for amplifying nucleic acids may include, e.g., PCR reagents, including but not limited to DNA polymerase, RNA polymerase, PCR buffer, magnesium chloride solutions, nucleic acid primers (e.g., primers designed to target particular biomarkers of responsiveness to a target drug of interest), and/or any other PCR reagents as are well known in the art. In some embodiments, a kit of the invention includes one or more probes capable of detecting one or more biomarkers of responsiveness to a target drug of interest. Such probes can, for example, include nucleic acids capable of hybridizing to the biomarker based on nucleic acid sequence complementarity. In certain embodiments, a probe has at least 85% sequence identity (e.g., 85%, 90%, 95%, 97%, 98%, 99%, or 100% sequence identity) to a nucleic acid sequence that is complementary or identical to at least 5 (e.g., at least 15) consecutive nucleotides of one or more biomarkers. The probes can be attached a solid surface, such as a microarray. In certain embodiments, the kit includes NanoString capture probes, NanoString reporter probes, and/or one or more nCounter cartridges. In certain embodiments, the kit includes reagents for next generation sequencing, including but not limited to poly(T) oligonucleotides, dye terminators, sequencing adapters, adapter ligation reagents, reverse transcriptase, primers (e.g., random primers), DNA-cleaving enzymes, polymerases, and/or any combination thereof. In alternate embodiments, the kit includes a protein array and/or reagents for detection of the polypeptide gene products of one or more biomarkers of responsiveness, such as those described herein.

The invention further includes kits for administering one or more target drugs, including but not limited to 5-FU, irinotecan, and oxaliplatin, as well as analogs thereof, such as prodrugs, derivatives, metabolites, enantiomers, and combinations thereof. For example, 5-FU prodrugs that can be included in kits of the invention include capecitabine and tegafur. Such kits may contain a composition or formulation of the target drug in question, or an enantiomer, prodrug, metabolite, or pharmaceutically acceptable salt thereof, together with the customary items for administering the therapeutic ingredient as are known in the art. In certain embodiments, a kit for administering a target drug may further include any of the reagents, materials, kits, or devices described above.

The following examples are intended to illustrate, rather than limit, the invention.

EXAMPLES Example 1 Predicting Drug Responsiveness to 5-FU in Various Cancer Patient Populations

An mRNA-based predictor of responsiveness to 5-FU developed according to the methods of the invention was applied to 3522 patients having a variety of cancers, from each of whom we have a pre-treatment measurement of gene expression with an Affymetrix array of either type U133A or U133Plus2. When the patients were grouped by indication (e.g., a particular cancer exhibited by the patient), it was possible to compare the indications and identify particular cancer types predicted to be more sensitive to 5-FU (FIG. 1). In an analysis of 27 different cancer indications, it was predicted that chronic myelogenous leukemia—chronic phase, acute lymphoblastic leukemia, colon cancer, hepatocellular carcinoma, and multiple myeloma were most sensitive to 5-FU. In a similar analysis of 62 cancer drugs approved by the FDA, the indication for which 5-FU treatment was approved by the FDA was (in 13 cases) predicted by our drug response predictor as “most sensitive” to 5-FU treatment (out of the 28 indications examined in our preclinical analysis). In 33 cases, the indication approved was among the top five predictions. This indicates that our pre-clinical prediction of indication sensitivity can successfully predict the indication that is later approved by the FDA. Also, in prior analyses of drugs tested in such studies, we have found that a difference in predicted sensitivity translated to a difference in clinical response rate. Table 13 ranks all 27 indications according to their predicted mean sensitivity to 5-FU.

TABLE 13 27 indications ordered by rank of their mean predicted sensitivity to 5-fluorouracil. The reference cites the publication of the trial from which the samples were obtained. Rank Abbrev. Full name Reference 1 CMLCP Chronic myelogenous leukemia - cronic Bruennert phase 2 ALL Acute lympho-blastic leukemia Ross (2003); Holleman 3 Colon Colon Cancer Smith; Khambata-Ford 4 HCC Hepatocellular Carcinoma Liao 5 MM Multiple Myeloma Agnelli 6 AML Acute myelogenous leukemia Metzeler; Lubbert; Ross (2004) 7 DLBCL Diffuse Large B cell lymphoma Hummel; Lenz 8 eso Esophageal cancer Kimchi 9 MDS Myelodysplastic syndrome Mills 10 CLL Chronic lymphocytic leukemia Ouilette 11 ERpos ERpos breast cancer Hess 12 PTCL Peripheral T-cell lymphoma Piccaluga 13 Breast Breast cancer Hess; Zhang 14 ovary Ovarian Cancer Bild; Denkert 15 Bladder Bladder Cancer Dyrksjot 16 RCC Renal Cell Carcinoma Lenburg 17 Hodgkin Hodgkin's lymphoma VanLoo; Steidl; Chetaille 18 Cervix Cervical cancer Scotto 19 pancreas Pancreatic cancer Gautier 20 NSCLC Non small cell lung cancer Bild 21 Prosta Prostate cancer Wanf 22 CTCL Cutaneous T-Cell lymphoma Shin 23 Melan Melanoma Xu 24 SCCHN Squamous Cell Carcinoma of the Head Slebos and Neck 25 glioma Glioma Freije 26 GIST Gastrointestinal Stromal Tumor Yamaguchi; Ostrowski; Astolfi 27 Sarcom Sarcoma Barretina

Subgroup Analysis in Non-Small Cell Lung Cancer (NSCLC)

The predicted sensitivity to 5-FU was compared among different subgroups of NSCLC. A dataset of 226 primary adenocarcinomas with corresponding mutation statuses was obtained from Japan (see PMID: 22080568). FIG. 2 shows the predicted sensitivity to 5-FU for each sample, according to mutation status. A Wilcoxon rank test was run to compare the three mutation subgroups to wild type: EGFR P-value: 0.27, KRAS P-value: 0.032, ALK fusion P-value: 0.091.

Subgroup Analysis in Breast Cancer

The predicted sensitivity to 5-FU was compared among different subgroups of breast cancer. A dataset of 243 breast cancer specimens was obtained (Hess, 2006). FIG. 3 shows the predicted sensitivity to 5-FU for each specimen, according to ER, HER2, and PR status. A Wilcoxon rank test was run to compare the three receptor subtypes to their wild type counterpart: ERpos versus ERneg P-value: 0.11, PRpos versus PRneg P-value: 0.8, HER2pos versus HER2neg P-value: 0.24, triple negative versus not triple negative P-value: 0.048.

Drug Combinations

The strategy behind drug combination therapy is to exploit multiple targets in, e.g., anticancer treatment and thereby increase response. As drug similarity is revealed according to the present invention, it can be used for selecting drugs for combination therapy by selecting drugs that show little similarity. Here, the predictor of response to 5-FU was compared to other drug response predictors in order to identify candidates for combination treatment. If a patient predicted to be responsive to 5-FU was likewise predicted to be responsive to a given combination drug candidate, then that drug would be considered as a poor candidate, as in such a case, a trial comparing the drug with or without combination with 5-FU would be predicted to provide little difference between the two arms. Conversely, it is predicted that a trial comparing a good combination candidate (e.g., a drug having different predictors of responsiveness from 5-FU) with or without 5-FU will give greater response rate in the 5-FU arm, because patients that fail therapy with the good combination candidate are likely to respond to 5-FU.

The analysis has to be performed on specific patients with a specific disease. It is not certain that the pattern would be the same if another disease is chosen. We decided to use 243 breast cancer specimens from a published cohort (Hess, 2006). If other indications are to be considered, it is possible to repeat the analysis in a different indication and see if the results change. Candidate drugs were selected according to the following criteria: (1) FDA approved, (2) NCI60 growth inhibition data available, with more than 2 sensitive cell lines, (3) in vitro correlation between prediction and cell line test set greater than 0.15. A total of 52 anticancer drugs met these criteria, and response predictors were thus developed for these drugs using the same procedure as was used for the 5-FU predictor. The Pearson correlation between the predicted sensitivity to the drug and to 5-FU was calculated using the 243 breast cancer patients. The most promising candidate drugs would have a negative CC, meaning that their predicted sensitivity in breast cancer is negatively correlated with sensitivity to 5-FU. The 95% confidence interval was calculated based on the 243 patients.

TABLE 14 Candidate combination drugs sorted according to Pearson correlation to 5-FU in breast cancer. Pearson Rank Drug CC 95% C.I. 1 Afinitor (everolimus) −0.74 −0.79 −0.674 2 Temsirolimus (Torisel) −0.63 −0.703 −0.552 3 Bleomycin −0.55 −0.628 −0.45 4 Lomustine −0.46 −0.555 −0.356 5 Depsipeptide (ISTODAX) −0.42 −0.516 −0.307 6 Carboplatin −0.35 −0.457 −0.236 7 Bortezomib −0.32 −0.431 −0.205 8 Erlotinib (tarceva) −0.32 −0.426 −0.199 9 Gemcitabine (Gemzar) −0.32 −0.424 −0.197 10 Gemcitabine (Gemzar) −0.32 −0.424 −0.197 11 Mitoxantrone −0.31 −0.423 −0.196 12 Cisplatin −0.2 −0.317 −0.0748 13 Busulfan −0.16 −0.277 −0.0317 14 Epirubicin (epiadriamycin) −0.16 −0.276 −0.0301 15 Arsenic trioxide (Trisenox) −0.15 −0.27 −0.0238 16 bendamustine (Treanda) −0.14 −0.261 −0.0141 17 Irinotecan −0.14 −0.257 −0.0104 18 Vincristine −0.12 −0.241 0.00706 19 Fulvestrant −0.098 −0.222 0.0277 20 Teniposide −0.096 −0.219 0.0306 21 Adriamycin −0.091 −0.215 0.0349 22 5-Aza-2′-deoxycytidine (decitabine) −0.037 −0.163 0.0888 23 Estramustine −0.0074 −0.133 0.119 24 Leukeran (Chlorambucil) 0.0033 −0.123 0.129 25 Melphalan 0.006 −0.12 0.132 26 Hydroxyurea 0.014 −0.112 0.14 27 Ixabepilone (Ixempra) 0.018 −0.108 0.143 28 Procarbazine (Matulane) 0.032 −0.094 0.157 29 Sorafenib (Nexavar) 0.033 −0.093 0.158 30 Thiotepa (Thioplex) 0.045 −0.0813 0.17 31 Vinblastine (velban) 0.045 −0.0812 0.17 32 Daunorubicin 0.048 −0.0781 0.173 33 Vinorelbine (Navelbine) 0.049 −0.0776 0.174 34 Dacarbazine 0.053 −0.0738 0.177 35 Valrubicin (Valstar) 0.064 −0.0626 0.188 36 Carmustine 0.083 −0.0432 0.207 37 Exemestane 0.11 −0.0172 0.232 38 Tamoxifen 0.15  0.022 0.268 39 Eribulin 0.18  0.0519 0.296 40 Fludarabine 0.18  0.0541 0.298 41 Iressa 0.2  0.0815 0.323 42 Ara-C (Cytarabine hydrochloride) 0.25  0.13 0.366 43 Mechlorethamine 0.26  0.134 0.37 44 Idarubicin 0.29  0.173 0.404 45 Gleevec (Imatinib) 0.36  0.247 0.466 46 Lapatinib (Tykerb) 0.38  0.269 0.484 47 Taxotere (docetaxel) 0.41  0.303 0.512 48 Asparaginase (Elspar) 0.44  0.332 0.536 49 Thioguanine 0.45  0.348 0.548 50 Clofarabine (Clolar) 0.48  0.372 0.567 51 Nilotinib (Tasigna) 0.48  0.374 0.569 52 Mercaptopurine 0.5  0.398 0.588 53 Vorinostat (SAHA) 0.66  0.576 0.721 54 Paclitaxel (Taxol) 0.69  0.616 0.749 55 Oxaliplatin 0.72  0.654 0.776 56 Pralatrexate (Folotyn) 0.72  0.658 0.779 57 Methotrexate 0.85  0.811 0.882 58 5-Fluorouracil (5-FU) 0.99  0.992 0.995 95% C.I. = 95% confidence interval. CC = correlation coefficient.

The drugs Afinitor (everolimus), Temsirolimus (Torisel), Bleomycin, and Lomustine were predicted to be good candidates for combination therapy with 5-FU in breast cancer. FIG. 4 shows the predicted sensitivity of 243 breast cancer patients to 5-FU and to Afinitor (everolimus). For the drugs Vectibix and Bevacizumab, NCI60 in vitro data was absent. For the drugs Cetuximab and Xeloda, NCI60 data was of poor quality or inconclusive. The drugs Pemetrexed, Temozolomide, Mitomycin, Topotecan, Streptozocin, Herceptin, Anastrozole and Letrozole failed in our internal quality criteria.

Example 2 Predicting Survival in Colon Cancer Patients Treated with 5-FU

A clinical dataset of 232 pre-treatment fresh frozen colorectal cancer surgical biopsies was downloaded from Gene Expression Omnibus under accession number GSE17538. The biopsies were analyzed using the Affymetrix HG-U133-Plus_2 array type. The expression of NT5E was determined by reading the intensity of Affymetrix probeset 203939_at, which is predicted to be more highly expressed in 5-FU-resistant patients. Patients were predicted sensitive to 5-FU if the expression of NT5E was below the population median. Patients were predicted resistant if expression of NT5E was above the population median. As shown in FIG. 5, there was a statistically significant difference in survival between the predicted-sensitive group and the predicted-resistant group after months of adjuvant chemotherapy with 5-FU, with the predicted-sensitive group showing a significantly higher rate of survival than the predicted-resistant group (p=0.006).

If using more genes from Tables 1 and 2 than NT5E to predict sensitivity, the prediction can be performed as follows:

Prediction=mean(genes from Table 1)−mean(genes from Table 2)

Example 3 Predicting FOLFIRI Treatment Response in Colon Cancer Patients

A dataset of 40 formalin-fixed paraffin embedded (FFPE) colorectal cancer patient biopsies analyzed on the Almac Colorectal Cancer DSATM array type was downloaded from ArrayExpress under accession number E-MEXP-3549. The advantage of the Almac array compared to the HG-U133_Plus_2 array used in Example 2 is that the Almac array can use FFPE samples instead of fresh frozen samples. Fresh frozen samples are not routinely stored in surgical or pathological practice, but storing FFPE samples is standard procedure, and has been done for more than 100 years. Thus, the Almac array is logistically easier to incorporate into existing clinical practice than the HG-U133_Plus_2 array. All patients were treated with 5-FU and irinotecan (FOLFIRI).

The NT5E gene for 5-FU resistance was mapped to corresponding Almac probesets ADXCRAG_NM_002526_at (SEQ ID NO: 1015), ADXCRAG_NM_002526_s_at (SEQ ID NO: 1016), ADXCRPD.5241.C1_at (SEQ ID NO: 1683), ADXCRSS.Hs#S1299958_at (SEQ ID NO: 2064), ADXCRSS.Hs#53735513_at (SEQ ID NO: 2207), ADXCRAD_BX404438_s_at (SEQ ID NO: 2316), ADXCRAD_BM704188_at (SEQ ID NO: 2446), ADXCRAD_BG611920_at (SEQ ID NO: 2714), ADXCRAD_BC015940_at (SEQ ID NO: 2778) by using the file A-AFFY-101.adf.txt associated with the Almac array.

The PRF1 gene for irinotecan sensitivity was mapped to corresponding Almac probesets ADXCRAD_BQ654088_at (SEQ ID NO: 2314), ADXCRAD_BQ654088_x_at (SEQ ID NO: 2315), ADXCRAD_A1445650_at (SEQ ID NO: 2881).

FIG. 6 shows the predicted sensitivity to FOLFIRI based on the expression of the Almac probesets, based on the following algorithm:

Prediction=mean(PRF1 Almac probesets)−mean(NT5E Almac probesets)

normalized to a scale of 0 to 100 in the patients, when grouped according to clinical response to adjuvant chemotherapy with 5-FU and irinotecan. The population median was used as a cutoff between sensitive and resistant patients. The correlation between clinical response (CR=4,PR=2,SD=2,PD=1) and predicted sensitivity was evaluated with a Pearson correlation and gave a one-sided p-value of 0.004 and a correlation coefficient (CC) of 0.40.

If using more genes from Tables 1, 2, 3 and 4 to predict sensitivity, the genes can be mapped to the matching Almac probesets by lookup in file A-AFFY-101.adf.txt associated with the Almac array and available from ArrayExpress at http://www.ebi.ac.uk/arrayexpress/files/A-AFFY-101/A-AFFY-101.adf.txt. The prediction is then performed as follows:

Prediction=mean(probesets matching Table 1/3)−mean(probesets matching Table 2/4)

Example 4 Predicting FOLFOX Treatment Response in Colon Cancer Patients

A clinical dataset of 17 pre-treatment fresh frozen colorectal cancer surgical biopsies was downloaded from Gene Expression Omnibus under accession number GSE19860. The biopsies have been analyzed using the Affymetrix HG-U133-Plus_2 array type. All patients were treated adjuvantly with mFOLFOX6 (5-FU and oxaliplatin). The expression of NT5E was determined by reading the intensity of Affymetrix probeset 203939_at that is predicted higher expressed in 5-FU resistant patients. The expression of MRPL16 was determined by reading the intensity of Affymetrix probeset 217980_s_at that is predicted to be higher expressed in oxaliplatin sensitive patients.

FIG. 7 shows the predicted sensitivity to FOLFOX based on the following algorithm:

Prediction=217980_s_at−203939_s_at

normalized to a scale of 0 to 100 in the patients when grouped according to clinical response to adjuvant chemotherapy with FOLFOX. The population median was used as a cutoff between sensitive and resistant patients. A t-test of difference in predicted sensitivity between responders and non-responders gave a statistically significant one-sided p-value of 0.015.

Example 5 Predicting 5-FU Treatment Responsiveness and Adjusting Subsequent Treatment

The diagnostic methods of the present invention can be used to predict the responsiveness of a subject (e.g., a subject suffering from or susceptible to colon cancer or breast cancer) to treatment with 5-FU or a prodrug for 5-FU, such as capecitabine or tegafur. A biological sample (e.g., a tumor biopsy) may be obtained from the subject through methods well known in the art. The sample may be frozen and/or prepared, e.g., by formalin fixation and paraffin embedding. mRNA can be isolated from the sample and a gene expression profile determined, e.g., using a microarray platform such as the Almac Colorectal Cancer DSATM array or the Affymetrix HG-U133-Plus_2 array. Alternatively, specific biomarkers of resistance and/or sensitivity to 5-FU can be measured, e.g., by microarray, sequencing, or PCR-based techniques, such as those described herein. For example, the expression levels of the 5-FU resistance biomarkers NT5E, CNN3, ACTN1, FLNA, and/or ATP2B4 can be determined. The expression levels of the 5-FU sensitivity biomarkers APRT, GSR, TUFM, MRPS2, and/or MTHFD2 can also be determined. An elevated level of one or more of the biomarkers of resistance and/or sensitivity can indicate the responsiveness of the subject to treatment with 5-FU. For example, an elevated level of one or more 5-FU resistance biomarkers in the subject, relative to a control (e.g., the population median) can indicate that the subject is resistant to 5-FU treatment. Alternatively, for example, an elevated level of one or more 5-FU sensitivity biomarkers in the subject, relative to a control (e.g., the population median) can indicate that the subject is sensitive to 5-FU treatment. Furthermore, the relative expression levels of 5-FU resistance and sensitivity biomarkers can indicate the responsiveness of the subject to 5-FU treatment.

If a subject is predicted to be sensitive to 5-FU treatment, then subsequent treatment of the subject can be altered, e.g., to include 5-FU and/or a prodrug thereof (e.g., capecitabine or tegafur), or to decrease dosage, frequency of administration, and/or length of treatment with 5-FU and/or a prodrug thereof (e.g., capecitabine or tegafur). Conversely, if a subject is predicted to be resistant to 5-FU treatment, then subsequent treatment of the subject can be altered, e.g., to omit 5-FU and/or a prodrug thereof (e.g., capecitabine or tegafur), or to increase dosage, frequency of administration, and/or length of treatment with 5-FU and/or a prodrug thereof (e.g., capecitabine or tegafur). Furthermore, a subject predicted to be resistant to 5-FU can be administered drugs other than 5-FU, such as irinotecan, oxaliplatin, and/or another chemotherapeutic agent as described herein.

Example 6 Predicting Irinotecan Treatment Responsiveness and Adjusting Subsequent Treatment

The diagnostic methods of the present invention can be used to predict the responsiveness of a subject (e.g., a subject suffering from or susceptible to colon cancer or breast cancer) to treatment with irinotecan. A biological sample (e.g., a tumor biopsy) may be obtained from the subject through methods well known in the art. The sample may be frozen and/or prepared, e.g., by formalin fixation and paraffin embedding. mRNA can be isolated from the sample and a gene expression profile determined, e.g., using a microarray platform such as the Almac Colorectal Cancer DSATM array or the Affymetrix HG-U133-Plus_2 array. Alternatively, specific biomarkers of resistance and/or sensitivity to irinotecan can be measured, e.g., by microarray, sequencing, or PCR-based techniques, such as those described herein. For example, the expression levels of the irinotecan sensitivity biomarkers PRF1, GZMB, PTPRC, PTPRC, and/or PTPRCAP can be determined. The expression levels of the irinotecan resistance biomarkers CCND1, LGALS3, INPP4B, TMEM97, and/or TCF7L2 can also be determined. An elevated level of one or more of the biomarkers of resistance and/or sensitivity can indicate the responsiveness of the subject to treatment with irinotecan. For example, an elevated level of one or more irinotecan resistance biomarkers in the subject, relative to a control (e.g., the population median) can indicate that the subject is resistant to irinotecan treatment. Alternatively, for example, an elevated level of one or more irinotecan sensitivity biomarkers in the subject, relative to a control (e.g., the population median) can indicate that the subject is sensitive to irinotecan treatment. Furthermore, the relative expression levels of irinotecan resistance and sensitivity biomarkers can indicate the responsiveness of the subject to irinotecan treatment.

If a subject is predicted to be sensitive to irinotecan treatment, then subsequent treatment of the subject can be altered, e.g., to include irinotecan or to decrease dosage, frequency of administration, and/or length of treatment with irinotecan. Conversely, if a subject is predicted to be resistant to irinotecan treatment, then subsequent treatment of the subject can be altered, e.g., to omit irinotecan or to increase dosage, frequency of administration, and/or length of treatment with irinotecan. Furthermore, a subject predicted to be resistant to irinotecan can be administered drugs other than irinotecan, such as 5-FU, capecitabine, tegafur, oxaliplatin, and/or another chemotherapeutic agent as described herein.

Example 7 Predicting Oxaliplatin Treatment Responsiveness and Adjusting Subsequent Treatment

The diagnostic methods of the present invention can be used to predict the responsiveness of a subject (e.g., a subject suffering from or susceptible to colon cancer or breast cancer) to treatment with oxaliplatin. A biological sample (e.g., a tumor biopsy) may be obtained from the subject through methods well known in the art. The sample may be frozen and/or prepared, e.g., by formalin fixation and paraffin embedding. mRNA can be isolated from the sample and a gene expression profile determined, e.g., using a microarray platform such as the Almac Colorectal Cancer DSATM array or the Affymetrix HG-U133-Plus_2 array. Alternatively, specific biomarkers of resistance and/or sensitivity to oxaliplatin can be measured, e.g., by microarray, sequencing, or PCR-based techniques, such as those described herein. For example, the expression levels of the oxaliplatin sensitivity biomarkers MRPL16, ANP32A, SRSF2, PDSS1, and/or PRIM1 can be determined. The expression levels of the oxaliplatin resistance biomarkers LPP, RHOC, CAPN2, FLNA, and/or WDR1 can also be determined. An elevated level of one or more of the biomarkers of resistance and/or sensitivity can indicate the responsiveness of the subject to treatment with oxaliplatin. For example, an elevated level of one or more oxaliplatin resistance biomarkers in the subject, relative to a control (e.g., the population median) can indicate that the subject is resistant to oxaliplatin treatment. Alternatively, for example, an elevated level of one or more oxaliplatin sensitivity biomarkers in the subject, relative to a control (e.g., the population median) can indicate that the subject is sensitive to oxaliplatin treatment. Furthermore, the relative expression levels of oxaliplatin resistance and sensitivity biomarkers can indicate the responsiveness of the subject to oxaliplatin treatment.

If a subject is predicted to be sensitive to oxaliplatin treatment, then subsequent treatment of the subject can be altered, e.g., to include oxaliplatin or to decrease dosage, frequency of administration, and/or length of treatment with oxaliplatin. Conversely, if a subject is predicted to be resistant to oxaliplatin treatment, then subsequent treatment of the subject can be altered, e.g., to omit oxaliplatin or to increase dosage, frequency of administration, and/or length of treatment with oxaliplatin. Furthermore, a subject predicted to be resistant to oxaliplatin can be administered drugs other than oxaliplatin, such as 5-FU, capecitabine, tegafur, irinotecan, and/or another chemotherapeutic agent as described herein.

Other Embodiments

All publications, patents, and patent applications mentioned in the above specification are hereby incorporated by reference to the same extent as if each individual publication, patent or patent application was specifically and individually indicated to be incorporated by reference in its entirety. Various modifications and variations of the described methods, pharmaceutical compositions, and kits of the invention will be apparent to those skilled in the art without departing from the scope and spirit of the invention. Although the invention has been described in connection with specific embodiments, it will be understood that it is capable of further modifications and that the invention as claimed should not be unduly limited to such specific embodiments. Indeed, various modifications of the described modes for carrying out the invention that are obvious to those skilled in the art are intended to be within the scope of the invention. This application is intended to cover any variations, uses, or adaptations of the invention following, in general, the principles of the invention and including such departures from the present disclosure come within known customary practice within the art to which the invention pertains and may be applied to the essential features herein before set forth. 

What is claimed is: 1-551. (canceled)
 552. A method of testing a tumor sample of a subject having a known cancer type and for which responsiveness to treatment with 5-fluorouracil (5-FU), irinotecan, or oxaliplatin is unknown, said method comprising: (a) contacting the tumor sample from the subject comprising one or more nucleic acid molecules with a device comprising: (i) single-stranded nucleic acid molecules capable of specifically hybridizing with the nucleotides of one or more biomarkers of resistance to 5-fluorouracil (5-FU), irinotecan, or oxaliplatin selected from the biomarkers of Table 2, Table 3, or Table 5, respectively; and/or (ii) single-stranded nucleic acid molecules capable of specifically hybridizing with the nucleotides of one or more biomarkers of sensitivity to 5-fluorouracil (5-FU), irinotecan, or oxaliplatin selected from the biomarkers of Table 1, Table 4, or Table 6, respectively; and (b) detecting a level of expression of the one or more biomarkers of resistance and/or the one or more biomarkers of sensitivity by performing microarray analysis or quantitative reverse transcriptase polymerase chain reaction (qRT-PCR).
 553. The method of claim 552, further comprising, prior to step (a) or (b), providing said tumor sample from said subject.
 554. The method of claim 552, wherein said method further comprises (c) calculating a difference score for the subject by subtracting the mean expression levels of the one or more biomarkers of resistance from the mean expression levels of the one or more biomarkers of sensitivity.
 555. The method of claim 552, further comprising administering 5-FU, irinotecan, or oxaliplatin to said subject, wherein the subject has been determined to be responsive 5-FU, irinotecan, or oxaliplatin, respectively.
 556. The method of claim 552, wherein said device comprises: (i) said single-stranded nucleic acid molecules capable of specifically hybridizing with the nucleotides of the one or more biomarkers of resistance to 5-fluorouracil (5-FU), irinotecan, or oxaliplatin; and (ii) said single-stranded nucleic acid molecules capable of specifically hybridizing with the nucleotides of the one or more biomarkers of sensitivity to 5-fluorouracil (5-FU), irinotecan, or oxaliplatin.
 557. A method of treating cancer in a subject in need thereof comprising: (a) performing the method of claim 552; and (b) administering 5-FU, irinotecan, or oxiplatin to said subject.
 558. A method of treating cancer in a subject in need thereof comprising administering 5-FU, irinotecan, or oxiplatin to said subject, wherein the subject has been determined to be responsive to 5-FU, irinotecan, or oxiplatin according to a method comprising: (a) contacting a tumor sample from the subject comprising one or more nucleic acid molecules with a device comprising: (i) single-stranded nucleic acid molecules capable of specifically hybridizing with the nucleotides of one or more biomarkers of resistance to 5-fluorouracil (5-FU), irinotecan, or oxaliplatin selected from the biomarkers of Table 2, Table 3, or Table 5, respectively; and/or (ii) single-stranded nucleic acid molecules capable of specifically hybridizing with the nucleotides of one or more biomarkers of sensitivity to 5-fluorouracil (5-FU), irinotecan, or oxaliplatin selected from the biomarkers of Table 1, Table 4, or Table 6, respectively; and (b) detecting a level of expression of the one or more biomarkers of resistance and/or the one or more biomarkers of sensitivity by performing microarray analysis or quantitative reverse transcriptase polymerase chain reaction (qRT-PCR).
 559. The method of claim 558, wherein said device comprises: (i) said single-stranded nucleic acid molecules capable of specifically hybridizing with the nucleotides of the one or more biomarkers of resistance to 5-fluorouracil (5-FU), irinotecan, or oxaliplatin; and (ii) said single-stranded nucleic acid molecules capable of specifically hybridizing with the nucleotides of the one or more biomarkers of sensitivity to 5-fluorouracil (5-FU), irinotecan, or oxaliplatin.
 560. The method of claim 558, further comprising administering one or more additional therapies to said subject, wherein said one or more additional therapies is administered: (a) concurrently with said administration of 5-FU, irinotecan, or oxaliplatin; or (b) separately from said administration of 5-FU, irinotecan, or oxaliplatin; or (c) prior to with said administration of 5-FU, irinotecan, or oxaliplatin; or (d) after with said administration of 5-FU, irinotecan, or oxaliplatin.
 561. The method of claim 560, wherein said one or more additional therapies is administered within 1 week of said administration of 5-FU, irinotecan, or oxaliplatin.
 562. The method of claim 560, wherein said one or more additional therapies comprises one or more additional therapeutic agents, surgery, or radiation therapy.
 563. The method of claim 562, wherein said one or more additional therapies comprises one or more additional therapeutic agents, wherein said 5-FU, irinotecan, or oxaliplatin is administered alone or in admixture with said one or more additional therapeutic agents.
 564. The method of claim 563 wherein said one or more additional therapeutic agents is selected from: (a) the group consisting of: 5-FU, irinotecan, oxaliplatin, cetuximab, leucovorin, SN-38, everolimus, temsirolimus, bleomycin, lomustine, depsipeptide, carboplatin, bortezomib, erlotinib, gemcitabine, mitoxantrone, cisplatin, busulfan, epirubicin, arsenic trioxide, bendamustine, vincristine, fulvestrant, teniposide, adriamycin, decitabine, and estramustine; or (b) everolimus, temsirolimus, bleomycin, or lomustine; or (c) leucovorin and at least one of 5-FU, irinotecan, or oxaliplatin.
 565. The method of claim 558, wherein said 5-FU, irinotecan, or oxaliplatin is administered to said subject intravenously, orally, intraperitoneally, intramuscularly, topically, rectally, cutaneously, subcutaneously, nasally, intracerebroventricularly, intraparenchymally, intrathecally, intracranially, ocularly, via inhalation, or through the skin.
 566. The method of claim 565, wherein said 5-FU, irinotecan, or oxaliplatin is administered to said subject: (a) once daily; and/or (b) once daily, for up to four years; and/or (c) once weekly, once every other week, or once every three weeks; and/or (d) in six week cycles; and/or (c) repeated 30 days after the completion of the previous administration; and/or (d) repeated for at least 12 to 60 months.
 567. The method of claim 558, wherein said 5-FU, irinotecan, or oxaliplatin is administered in dosage form, wherein: (a) said daily dose of 5-FU is up to 800 mg; or (b) said daily dose of irinotecan is up to 125 mg/m², 180 mg/m², or 350 mg/m²; or (c) said daily dose of oxaliplatin is up to 85 mg/m².
 568. The method of claim 558, wherein said step (a) or (b) occurs: (a) prior to said administration; or (b) concurrent with said administration; or (c) after said administration; and/or (d) multiple times.
 569. The method of claim 552, wherein: (a) said treatment is 5-FU and said biomarker of resistance is NT5E; or (b) said treatment is irinotecan and said biomarker of sensitivity is PRF1; or (c) said treatment is oxaliplatin and said biomarker of sensitivity is selected from MRPL16 and at least a second biomarker of sensitivity selected from the biomarkers of Table
 5. 570. The method of claim 569, wherein said second biomarker of sensitivity is selected from the group consisting of: ANP32A, SRSF2, PDSS1, PRIM1, HNRNPA1, NDUFAB1, GLTSCR2, RNPS1, and ICAM2.
 571. The method of claim 569, wherein said biomarker of sensitivity is selected from MRPL16 and said biomarker of resistance is selected from one or more of the biomarkers of Table
 6. 572. The method of claim 571, wherein said biomarker of resistance is selected from the group consisting of: LPP, RHOC, CAPN2, FLNA, WDR1, FLNA, ACTN1, CNN3, FLNA, and ACTN1.
 573. The method of claim 552, wherein the device is a microarray.
 574. The method of claim 552, wherein the device is for performing a qRT-PCR reaction.
 575. The method of claim 552, wherein: (a) said treatment is 5-FU and said one or more biomarkers of resistance is selected from the group consisting of: NT5E, CNN3, ACTN1, FLNA, ATP2B4, CYR61, LGALS1, RHOC, RAB32, and TMEM158; and/or said one or more biomarkers of sensitivity is selected from the group consisting of: APRT, GSR, TUFM, MRPS2, MTHFD2, WDR59, ANP32B, PMM2, STOML2, and NDUFAB1; or (b) said treatment is irinotecan and said one or more biomarkers of sensitivity is selected from the group consisting of: PRF1, GZMB, PTPRC, PTPRC, PTPRCAP, PDE4DIP, ACAP1, PTPRC, S1PR1, and DOCK2; and/or one or more biomarkers of resistance is selected from the group consisting of: CCND1, LGALS3, INPP4B, TMEM97, TCF7L2, SFN, LAPTM4B, LSR, SFN, and TMEM97; or (c) said treatment is oxaliplatin and said one or more biomarkers of sensitivity is selected from the group consisting of: MRPL16, ANP32A, SRSF2, PDSS1, PRIM1, HNRNPA1, NDUFAB1, GLTSCR2, RNPS1, and ICAM2; and/or one or more biomarkers of resistance is selected from the group consisting of: LPP, RHOC, CAPN2, FLNA, WDR1, FLNA, ACTN1, CNN3, FLNA, and ACTN1.
 576. The method of claim 575, wherein: (a) the level of expression of said one or more biomarkers of sensitivity in said subject is statistically the same as the level of expression of said one or more biomarkers of sensitivity in a control subject sensitive to said treatment and wherein the subject is sensitive to said treatment; or (b) the level of expression of said one or more biomarkers of resistance in said subject is statistically different from the level of expression of said one or more biomarkers of resistance in a control subject resistant to said treatment and wherein the subject is sensitive to said treatment; or (c) the level of expression of said one or more biomarkers of sensitivity in said subject is statistically different from the level of expression of said one or more biomarkers of sensitivity in a control subject sensitive to said treatment and wherein the subject is resistant to said treatment; or (d) the level of expression of said one or more biomarkers of resistance in said subject is statistically the same as the level of expression of said one or more biomarkers of resistance in a control subject resistant to said treatment and wherein the subject is resistant to said treatment.
 577. The method of claim 576, wherein said level of expression in said subject is significantly higher or significantly lower than in said control.
 578. The method of claim 552, wherein responsiveness of the subject to combination treatment with oxaliplatin and 5-FU is unknown; and wherein the biomarker of sensitivity for oxaliplatin is MRPL16.
 579. The method of claim 578, wherein said one or more biomarkers of resistance to 5-FU is selected from the group consisting of: NT5E, CNN3, ACTN1, FLNA, ATP2B4, CYR61, LGALS1, RHOC, RAB32, and TMEM158.
 580. The method of claim 578, wherein the method further comprises calculating a difference score for the subject by subtracting the mean expression level of MRPL16 from the mean expression levels of said one or more biomarkers of resistance to 5-FU.
 581. The method of claim 552, further comprising determining the expression level of one or more additional biomarkers, wherein said one or more additional biomarkers is selected from the group consisting of: carcinoembryonic antigen (CEA), BRAF, KRAS, Fas-ligand, p53, Ki-67, thymidylate-synthase, dihydropyrimidine dehydrogenase, thymidine phosphorylase, microsatellite instability (MIS), and 18q allelic loss of heterozygosity (LOH18q):
 582. The method of claim 552, wherein said method further comprises, prior to step (a) or (b), amplifying said nucleotides of said one or more biomarkers of resistance and/or said one or more biomarkers of sensitivity from said tumor samples, wherein, optionally, prior to said amplification, said nucleotides are subjected to reverse transcription.
 583. The method of claim 552, wherein step (a) and (b) are performed using the same tumor sample or two or more different tumor samples.
 584. The method of claim 552, wherein the tumor sample is: (a) formalin-fixed paraffin embedded (FFPE) tissue; and/or (b) fresh frozen tissue; and/or (c) obtained from a tumor or a tumor biopsy.
 585. The method of claim 552, wherein the cancer has been resected from said subject.
 586. The method of claim 552 wherein said cancer is selected from the group consisting of: colorectal cancer, leukemia, myeloma, myelodysplastic syndrome, lymphoma, cervical cancer, prostate cancer, esophageal cancer, melanoma, glioma, pancreatic cancer, ovarian cancer, gastrointestinal stromal tumor, sarcoma, breast cancer, ER-positive cancer, bladder cancer, head and neck cancer, lung cancer, metastatic cancer, oral cavity cancer, uterine cancer, testicular cancer, skin cancer, thyroid cancer, brain cancer, stomach cancer, intra-epithelial cancer, bone cancer, biliary tract cancer, eye cancer, liver cancer, larynx cancer, kidney cancer, gastric cancer, blastoma, polycythemia vera, chordoma, synovioma, mesothelioma, adenocarcinoma, sweat gland carcinoma, sebaceous gland carcinoma, cystadenocarcinoma, bile duct carcinoma, choriocarcinoma, epithelial carcinoma, ependymoma, pinealoma, acoustic neuroma, schwannoma, meningioma, pituitary adenoma, nerve sheath tumor, cancer of the small intestine, cancer of the endocrine system, cancer of the penis, cancer of the urethra, cutaneous or intraocular melanoma, a gynecologic tumor, solid tumors of childhood, and neoplasms of the central nervous system.
 587. The method of claim 586, wherein: (a) said colorectal cancer is selected from the group consisting of: adenocarcinoma, gastrointestinal carcinoid tumor, primary colorectal lymphoma, leiomyosarcoma, colorectal melanoma, and squamous cell carcinoma; or (b) said breast cancer is medullary carcinoma; or (c) said leukemia is acute myeloid leukemia, acute lymphoid leukemia, chronic myeloid leukemia, chronic lymphocytic leukemia, acute myeloblastic leukemia, acute promyelocytic leukemia, acute myelomonocytic leukemia, acute monocytic leukemia, acute erythroleukemia, or chronic leukemia; or (d) said myeloma is multiple myeloma; or (e) said lymphoma is diffuse large B-cell lymphoma, cutaneous T-cell lymphoma, peripheral T-cell lymphoma, Hodgkin's lymphoma, non-Hodgkin's lymphoma, Waldenstrom's macroglobulinemia, or lymphocytic lymphoma; or (f) said glioma is oligodendroglioma; or (g) said pancreatic cancer is adenosquamous carcinoma, signet ring cell carcinoma, hepatoid carcinoma, colloid carcinoma, islet cell carcinoma, or pancreatic neuroendocrine carcinoma; or (h) said ovarian cancer is ovarian adenocarcinoma or embryonal carcinoma; or (i) said sarcoma is fibrosarcoma, myxosarcoma, liposarcoma, chondrosarcoma, osteogenic sarcoma, angiosarcoma, endotheliosarcoma, lymphangiosarcoma, lymphangioendotheliosarcoma, leiomyosarcoma, Ewing's sarcoma, or rhabdomyosarcoma; or (j) said head and neck cancer is squamous cell carcinoma of the head and neck; or (k) said lung cancer is non-small cell lung carcinoma, large cell carcinoma, bronchogenic carcinoma, or papillary adenocarcinoma; or (l) said testicular cancer is seminoma or embryonal carcinoma; or (m) said skin cancer is squamous cell carcinoma or basal cell carcinoma; or (n) said thyroid cancer is papillary carcinoma or medullary carcinoma; or (o) said brain cancer is astrocytoma or craniopharyngioma; or (p) said liver cancer is hepatocellular carcinoma or hepatoma; or (q) said kidney cancer is renal cell carcinoma or Wilms tumor; or (r) said blastoma is nephroblastoma, medulloblastoma, hemangioblastoma, neuroblastoma, or retinoblastoma.
 588. The method of claim 575, wherein: (a) the level of expression of said NT5E is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 94, 1015, 1016, 1683, 2064, 2207, 2316, 2446, 2714, or 2778; and/or (b) the level of expression of said CNN3 is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 95, 1157, 1476, or 1847; and/or (c) the level of expression of said ACTN1 is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 96, 934, 2203, 2469, 2737, 2816, or 2817; and/or (d) the level of expression of said FLNA is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 97, 1387, 1490, 1542, 1621, 1773, 1867, 1902, 1960, 2048, 2051, 2347, or 2348; and/or (e) the level of expression of said ATP2B4 is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 98, 1498, 1845, 2056, 2284, 2285, 2523, or 2627; and/or (f) the level of expression of said APRT is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 1 or 1201; and/or (g) the level of expression of said GSR is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 2, 907, 1148, 1722; and/or (h) the level of expression of said TUFM is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 3 or 1146; and/or (i) the level of expression of said MRPS2 is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 4 or 839; and/or (j) the level of expression of said MTHFD2 is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 5 or 1189; and/or (k) the level of expression of said PRF1 is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 209, 2314, 2315, or 2881; and/or (l) the level of expression of said GZMB is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 210, 1681, or 1682; and/or (m) the level of expression of said PTPRC is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 211, 212, 1020, 1632, 1675, 1998, 1999, 2535, 2636, or 2797; and/or (n) the level of expression of said PTPRCAP is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 213, 1645, or 1646; and/or (o) the level of expression of said CCND1 is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 354, 1592, 1593, 1679, 1727, 1752, 1817, 2013, or 2640; and/or (p) the level of expression of said LGALS3 is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 355, 1299, 1334, 1335, or 2069; and/or (q) the level of expression of said INPP4B is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 356, 919, 1453, 1616, 1617, 2199, 2386, 2625, or 2626; and/or (r) the level of expression of said TMEM97 is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 357, 966, 2532, or 2566; and/or (s) the level of expression of said TCF7L2 is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 358, 955, 1536, 1852, 2081, 2099, 2171, 2192, 2219, 2539, 2575, 2665, or 2880; and/or (t) the level of expression of said MRPL16 is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 399 or 1144; and/or (u) the level of expression of said ANP32A is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 400, 1921, 2357, 2358, 2736, 2799, or 2800; and/or (v) the level of expression of said SRSF2 is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 401; and/or (w) the level of expression of said PDSS1 is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 402, 862, or 2058; and/or (x) the level of expression of said PRIM1 is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 403, 2266, or 2267; and/or (y) the level of expression of said LPP is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 579, 984, 1031, 1437, 1693, 1731, 1828, 1831, 1872, 2040, 2063, 2104, 2109, 2119, 2123, 2160, 2197, 2400, 2401, 2618, 2784, 2852, or 2853; and/or (z) the level of expression of said RHOC is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 580; and/or (aa) the level of expression of said CAPN2 is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 581, 1521, 1552, 1900, 1965, 2154, 2233, 2234, or 2826; and/or (bb) the level of expression of said FLNA is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 582, 584, 587, 1387, 1490, 1542, 1621, 1773, 1867, 1902, 1960, 2048, 2051, 2347, or 2348; and/or (cc) the level of expression of said WDR1 is detected and wherein the single-stranded nucleic acid molecule is a probe capable of detecting a nucleic acid having the sequence of SEQ ID NO. 583, 894, 1135, 1136, 1390, 2194, 2335, 2506, 2839, or 2862; and/or
 589. The method of claim 588, wherein: (a) said probe for NT5E comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 94, 1015, 1016, 1683, 2064, 2207, 2316, 2446, 2714, or 2778; and/or (b) said probe for CNN3 comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 95, 1157, 1476, or 1847; and/or (c) said probe for ACTN1 comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 96, 934, 2203, 2469, 2737, 2816, or 2817; and/or (d) said probe for FLNA comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 97, 1387, 1490, 1542, 1621, 1773, 1867, 1902, 1960, 2048, 2051, 2347, or 2348; and/or (e) said probe for ATP2B4 comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 98, 1498, 1845, 2056, 2284, 2285, 2523, or 2627; and/or (f) said probe for APRT comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 1 or 1201; and/or (g) said probe for GSR comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 2, 907, 1148, 1722; and/or (h) said probe for TUFM comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 3 or 1146; and/or (i) said probe for MRPS2 comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 4 or 839; and/or (j) said probe for MTHFD2 comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 5 or 1189; and/or (k) said probe for PRF1 comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 209, 2314, 2315, or 2881; and/or (l) said probe for GZMB comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 210, 1681, or 1682; and/or (m) said probe for PTPRC comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 211, 212, 1020, 1632, 1675, 1998, 1999, 2535, 2636, or 2797; and/or (n) said probe for PTPRCAP comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 213, 1645, or 1646; and/or (o) said probe for CCND1 comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 354, 1592, 1593, 1679, 1727, 1752, 1817, 2013, or 2640; and/or (p) said probe for LGALS3 comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 355, 1299, 1334, 1335, or 2069; and/or (q) said probe for INPP4B comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 356, 919, 1453, 1616, 1617, 2199, 2386, 2625, or 2626; and/or (r) said probe for TMEM97 comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 357, 966, 2532, or 2566; and/or (s) said probe for TCF7L2 comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 358, 955, 1536, 1852, 2081, 2099, 2171, 2192, 2219, 2539, 2575, 2665, or 2880; and/or (t) said probe for MRPL16 comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 399 or 1144; and/or (u) said probe for ANP32A comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 400, 1921, 2357, 2358, 2736, 2799, or 2800; and/or (v) said probe for SRSF2 comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 401; and/or (w) said probe for PDSS1 comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 402, 862, or 2058; and/or (x) said probe for PRIM1 comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 403, 2266, or 2267; and/or (y) said probe for LPP comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 579, 984, 1031, 1437, 1693, 1731, 1828, 1831, 1872, 2040, 2063, 2104, 2109, 2119, 2123, 2160, 2197, 2400, 2401, 2618, 2784, 2852, or 2853; and/or (z) said probe for RHOC comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 580; and/or (aa) said probe for CAPN2 comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 581, 1521, 1552, 1900, 1965, 2154, 2233, 2234, or 2826; and/or (bb) said probe for FLNA comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 582, 584, 587, 1387, 1490, 1542, 1621, 1773, 1867, 1902, 1960, 2048, 2051, 2347, or 2348; and/or (cc) said probe for WDR1 comprises a sequence comprising at least 5 continuous nucleotides and at least 75% identity to a sequence complementary to SEQ ID NO. 583, 894, 1135, 1136, 1390, 2194, 2335, 2506, 2839, or
 2862. 590. A method of assessing the responsiveness of a subject to treatment with 5-FU, irinotecan, or oxaliplatin, comprising: (a) determining a level of expression of one or more biomarkers of sensitivity in one or more biological samples obtained from said subject; or (b) determining a level of expression of one or more biomarkers of resistance in one or more biological samples obtained from said subject; wherein said one or more biomarkers of sensitivity comprises a gene determined to have at least a 0.25 Pearson correlation between the mRNA expression level of said gene and growth inhibition of a cultured cell exposed to said 5-FU, irinotecan, or oxaliplatin, and/or said one or more biomarkers of resistance comprises a gene determined to have at least a −0.25 Pearson correlation between the mRNA expression level of said gene and growth inhibition of a cultured cell exposed to said 5-FU, irinotecan, or oxaliplatin; and wherein the levels of expression of said biomarker of sensitivity or said biomarker of resistance indicate whether said subject is responsive to said treatment. 